Updated on 2023/04/13

写真a

 
KOYANAGI Mitsumasa
 
Organization
Graduate School of Science Department of Biology Professor
School of Science Department of Biology
Title
Professor
Affiliation
Institute of Science
Affiliation campus
Sugimoto Campus

Position

  • Graduate School of Science Department of Biology 

    Professor  2022.04 - Now

  • School of Science Department of Biology 

    Professor  2022.04 - Now

Degree

  • D.sci ( Kyoto University )

Research Areas

  • Life Science / Animal physiological chemistry, physiology and behavioral biology  / Photobiology

  • Life Science / Genetics  / Molecular Evolution

Research Interests

  • Photobiology

  • Evolution

  • Optogenetics

  • Non-visual photoreception

  • Photoreceptor

  • GPCR

  • Sensory system

  • Light sensing

  • Vision

  • Color vision

Research subject summary

  • 動物は光を視覚や生物時計のリセットなど様々な形で利用しています。私は、光感覚の進化や多様性に興味をもって研究を行っています。動物はいつから光感覚を持ったのか?、最初はどのようなシステムだったのか?。また、私たちは視覚以外にも光や色を感じて何かに利用しているのではないか?といった疑問にDNAやタンパク質の解析からアプローチしています。

Research Career

  • Origin and diversity of the animal photoreception.

    photoreception, rhodopsin  Individual

    2005.04 

  • Functional analyses of non-image-forming color vision.

    non-visual, rhodopsin, color vision  Individual

    2006.04 

Professional Memberships

  • THE ZOOLOGICAL SOCIETY OF JAPAN

  • 日本進化学会

  • 日本比較生理生化学会

  • 日本分子生物学会

Committee Memberships (off-campus)

  • 近畿支部委員   日本動物学会  

    2017 - Now 

  • ZDW委員   日本動物学会  

    2016 - Now 

  • 庶務幹事   日本比較生理生化学会  

    2021 - Now 

  • 評議員   日本比較生理生化学会  

    2017 - Now 

  • 第90回大会実行委員   日本動物学会  

    2018 - 2019 

  • 第40回大会実行委員   日本比較生理生化学会  

    2017 - 2018 

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    日本比較生理生化学会

  • 男女共同参画委員   日本動物学会  

    2012 - 2020 

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Awards

  • 大阪市立大学教員活動表彰 特別表彰

    2018   大阪市立大学  

  • JSPS Award

    2017  

  • Promotion Award of the Zoological Society of Japan

    KOYANAGI Mitsumasa

    2013  

  • Nature Industry Award of Osaka Science and Technology Center

    2012  

  • Promotion Award of the Photobiology Association of Japan

    2012  

  • Yoshida Prize for Young Researchers of the Japanese Society for Comparative Physiology and Biochemistry

    2006  

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Job Career (off-campus)

  • JST   PRESTO Researcher (Concurrent)

    2013.10 - 2017.03

  • Osaka University   Graduate School of Science   Assistant Professor

    2004.04 - 2006.03

  • Japan Society of Promotion for Sciences   Postdoctoral Research Fellow (PD)

    2002.04 - 2004.03

  • Kyoto University   Graduate School of Science   Postdoctoral Fellow

    2001.04 - 2002.03

Education

  • Kyoto University   Doctor's Course   Graduated/Completed

    1997.04 - 2001.03

  • Kyoto University   Master's Course   Graduated/Completed

    1995.04 - 1997.03

  • Kyoto University     Graduated/Completed

    1991.04 - 1995.03

Papers

  • Whale shark rhodopsin adapted to deep-sea lifestyle by a substitution associated with human disease Reviewed

    Kazuaki Yamaguchi, Mitsumasa Koyanagi, Keiichi Sato, Akihisa Terakita, Shigehiro Kuraku

    Proceedings of the National Academy of Sciences   120 ( 13 )   2023.03

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    Authorship:Lead author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1073/pnas.2220728120

  • Multiple opsins in a reef-building coral, Acropora millepora Reviewed International coauthorship

    Benjamin M. Mason, Mitsumasa Koyanagi, Tomohiro Sugihara, Makoto Iwasaki, Vladlen Slepak, David J. Miller, Yusuke Sakai, Akihisa Terakita

    Scientific Reports   13 ( 1 )   2023.01

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    Abstract

    Opsins, light-sensitive G protein-coupled receptors, have been identified in corals but their properties are largely unknown. Here, we identified six opsin genes (acropsins 1–6) from a coral species Acropora millepora, including three novel opsins (acropsins 4–6), and successfully characterized the properties of four out of the six acropsins. Acropsins 1 and 6 exhibited light-dependent cAMP increases in cultured cells, suggesting that the acropsins could light-dependently activate Gs-type G protein like the box jellyfish opsin from the same opsin group. Spectral sensitivity curves having the maximum sensitivities at ~ 472 nm and ~ 476 nm were estimated for acropsins 1 and 6, respectively, based on the light wavelength-dependent cAMP increases in these opsins-expressing cells (heterologous action spectroscopy). Acropsin 2 belonging to the same group as acropsins 1 and 6 did not induce light-dependent cAMP or Ca<sup>2+</sup> changes. We then successfully estimated the acropsin 2 spectral sensitivity curve having its maximum value at ~ 471 nm with its chimera mutant which possessed the third cytoplasmic loop of the Gs-coupled jellyfish opsin. Acropsin 4 categorized as another group light-dependently induced intracellular Ca<sup>2+</sup> increases but not cAMP changes. Our results uncovered that the Acropora coral possesses multiple opsins coupling two distinct cascades, cyclic nucleotide and Ca<sup>2+</sup>signaling light-dependently.

    DOI: 10.1038/s41598-023-28476-5

    Other URL: https://www.nature.com/articles/s41598-023-28476-5

  • High-performance optical control of GPCR signaling by bistable animal opsins MosOpn3 and LamPP in a molecular property-dependent manner Reviewed

    Mitsumasa Koyanagi, Baoguo Shen, Takashi Nagata, Lanfang Sun, Seiji Wada, Satomi Kamimura, Eriko Kage-Nakadai, Akihisa Terakita

    Proceedings of the National Academy of Sciences   119 ( 48 )   2022.11

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    Authorship:Lead author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1073/pnas.2204341119

  • Optogenetic manipulation of Gq- and Gi/o-coupled receptor signaling in neurons and heart muscle cells

    Hanako Hagio, Wataru Koyama, Shiori Hosaka, Aysenur Deniz Song, Janchiv Narantsatsral, Koji Matsuda, Tomohiro Sugihara, Takashi Shimizu, Mitsumasa Koyanagi, Akihisa Terakita, Masahiko Hibi

    2022.10

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    Publishing type:Research paper (scientific journal)  

    Abstract

    G protein-coupled receptors (GPCRs) transmit extracellular signals into the cell depending on the type of G protein. To analyze the functions of GPCR signaling, we developed optogenetic tools using animal G protein-coupled bistable rhodopsins that can be controlled into active and inactive states by light irradiation. We expressed Gq- and Gi/o-coupled bistable rhodopsins in hindbrain reticulospinal V2a neurons, which are involved in locomotion, or in cardiomyocytes of zebrafish. Light stimulation of the reticulospinal V2a neurons expressing Gq-coupled spider Rh1 resulted in an increase in the level of cytoplasmic Ca<sup>2+</sup>and evoked swimming behavior. Light stimulation of cardiomyocytes expressing the Gi/o-coupled mosquito Opn3, pufferfish TMT opsin, or lamprey parapinopsin induced cardiac arrest, and the effect was suppressed by treatment with pertussis toxin or barium, suggesting that Gi/o-dependent regulation of inward-rectifier K<sup>+</sup>channels controls cardiac function. These data indicate that these rhodopsins are useful for optogenetic control of GPCR-mediated signaling in neurons and cardiomyocytesin vivo.

    Impact statement

    Animal G protein-coupled bistable rhodopsins can regulate Gq and Gi-mediated signaling in a light-dependent manner in neurons and cardiomyocytes, making them useful for analyzing roles of GPCR signalingin vivo.

    DOI: 10.1101/2022.10.25.513732

  • Expression of a homologue of a vertebrate non-visual opsin Opn3 in the insect photoreceptors. Reviewed

    Mitsumasa Koyanagi, Hayato Honda, Hirohisa Yokono, Ryu Sato, Takashi Nagata, Akihisa Terakita

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences   377 ( 1862 )   20210274 - 20210274   2022.10( ISSN:09628436

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    Authorship:Lead author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    Insect vision starts with light absorption by visual pigments based on opsins that drive Gq-type G protein-mediated phototransduction. Since Drosophila, the most studied insect in vision research, has only Gq-coupled opsins, the Gq-mediated phototransduction has been solely focused on insect vision for decades. However, genome projects on mosquitos uncovered non-canonical insect opsin genes, members of the Opn3 or c-opsin group composed of vertebrate and invertebrate non-visual opsins. Here, we report that a homologue of Opn3, MosOpn3 (Asop12) is expressed in eyes of a mosquito Anopheles stephensi. In situ hybridization analysis revealed that MosOpn3 is expressed in dorsal and ventral ommatidia, in which only R7 photoreceptor cells express MosOpn3. We also found that Asop9, a Gq-coupled visual opsin, exhibited co-localization with MosOpn3. Spectroscopic analysis revealed that Asop9 forms a blue-sensitive opsin-based pigment. Thus, the Gi/Go-coupled opsin MosOpn3, which forms a green-sensitive pigment, is co-localized with Asop9, a Gq-coupled opsin that forms a blue-sensitive visual pigment. Since these two opsin-based pigments trigger different phototransduction cascades, the R7 photoreceptors could generate complex photoresponses to blue to green light. This article is part of the theme issue 'Understanding colour vision: molecular, physiological, neuronal and behavioural studies in arthropods'.

    DOI: 10.1098/rstb.2021.0274

    PubMed

  • Squalomix: shark and ray genome analysis consortium and its data sharing platform. Reviewed

    Osamu Nishimura, John Rozewicki, Kazuaki Yamaguchi, Kaori Tatsumi, Yuta Ohishi, Tazro Ohta, Masaru Yagura, Taiki Niwa, Chiharu Tanegashima, Akinori Teramura, Shotaro Hirase, Akane Kawaguchi, Milton Tan, Salvatore D'Aniello, Filipe Castro, André Machado, Mitsumasa Koyanagi, Akihisa Terakita, Ryo Misawa, Masayuki Horie, Junna Kawasaki, Takashi Asahida, Atsuko Yamaguchi, Kiyomi Murakumo, Rui Matsumoto, Iker Irisarri, Norio Miyamoto, Atsushi Toyoda, Sho Tanaka, Tatsuya Sakamoto, Yasuko Semba, Shinya Yamauchi, Kazuyuki Yamada, Kiyonori Nishida, Itsuki Kiyatake, Keiichi Sato, Susumu Hyodo, Mitsutaka Kadota, Yoshinobu Uno, Shigehiro Kuraku

    F1000Research   11   1077 - 1077   2022( ISSN:20461402

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    The taxon Elasmobranchii (sharks and rays) contains one of the long-established evolutionary lineages of vertebrates with a tantalizing collection of species occupying critical aquatic habitats. To overcome the current limitation in molecular resources, we launched the Squalomix Consortium in 2020 to promote a genome-wide array of molecular approaches, specifically targeting shark and ray species. Among the various bottlenecks in working with elasmobranchs are their elusiveness and low fecundity as well as the large and highly repetitive genomes. Their peculiar body fluid composition has also hindered the establishment of methods to perform routine cell culturing required for their karyotyping. In the Squalomix consortium, these obstacles are expected to be solved through a combination of in-house cytological techniques including karyotyping of cultured cells, chromatin preparation for Hi-C data acquisition, and high fidelity long-read sequencing. The resources and products obtained in this consortium, including genome and transcriptome sequences, a genome browser powered by JBrowse2 to visualize sequence alignments, and comprehensive matrices of gene expression profiles for selected species are accessible through https://github.com/Squalomix/info.

    DOI: 10.12688/f1000research.123591.1

    PubMed

  • Whale shark rhodopsin adapted to its vertically wide-ranging lifestyle Reviewed

    Kazuaki Yamaguchi, Mitsumasa Koyanagi, Keiichi Sato, Akihisa Terakita, Shigehiro Kuraku

    2021.10

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    Publishing type:Research paper (scientific journal)  

    <title>Abstract</title>Spectral tuning of visual pigments often facilitates adaptation to new environments, and it is intriguing to study the visual ecology of pelagic sharks with expanded habitats. The whale shark, which dives into the deep sea of nearly 2,000 meters besides near-surface filter-feeding, was previously shown to possesses the ‘blue-shifted’ rhodopsin (RHO). In this study, our spectroscopy of recombinant whale shark RHO mutants revealed the dominant effect of the novel spectral tuning amino acid site 94, which is implicated in congenital stationary night blindness of humans, accounting for the blue shift. Thermal decay profiling revealed the reduction of the thermal stability of whale shark RHO, as typically observed for cone opsins, which was experimentally shown to be achieved by the site 178, as well as 94. The results suggest that these two sites cooperatively enhance the visual capacity in both the deep sea and the sea surface, enabling exceptionally wide vertical migration of this species.

    DOI: 10.1101/2021.10.01.462724

  • Insights into the evolutionary origin of the pineal color discrimination mechanism from the river lamprey Reviewed

    Wada Seiji, Kawano-Yamashita Emi, Sugihara Tomohiro, Tamotsu Satoshi, Koyanagi Mitsumasa, Terakita Akihisa

    BMC BIOLOGY   19 ( 1 )   188 - 188   2021.09

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    Publishing type:Research paper (scientific journal)  

    BACKGROUND: Pineal-related organs in cyclostomes, teleosts, amphibians, and reptiles exhibit color opponency, generating antagonistic neural responses to different wavelengths of light and thereby sensory information about its "color". Our previous studies suggested that in zebrafish and iguana pineal-related organs, a single photoreceptor cell expressing both UV-sensitive parapinopsin and green-sensitive parietopsin generates color opponency in a "one-cell system." However, it remains unknown to what degree these opsins and the single cell-based mechanism in the pineal color opponency are conserved throughout non-mammalian vertebrates. RESULTS: We found that in the lamprey pineal organ, the two opsins are conserved but that, in contrast to the situation in other vertebrate pineal-related organs, they are expressed in separate photoreceptor cells. Intracellular electrophysiological recordings demonstrated that the parietopsin-expressing photoreceptor cells with Go-type G protein evoke a depolarizing response to visible light. Additionally, spectroscopic analyses revealed that parietopsin with 11-cis 3-dehydroretinal has an absorption maximum at ~570 nm, which is in approximate agreement with the wavelength (~560 nm) that produces the maximum rate of neural firing in pineal ganglion cells exposed to visible light. The vesicular glutamate transporter is localized at both the parietopsin- and parapinopsin-expressing photoreceptor terminals, suggesting that both types of photoreceptor cells use glutamate as a transmitter. Retrograde tracing of the pineal ganglion cells revealed that the terminal of the parietopsin-expressing cells is located close enough to form a neural connection with the ganglion cells, which is similar to our previous observation for the parapinopsin-expressing photoreceptor cells and the ganglion cells. In sum, our observations point to a "two-cell system" in which parietopsin and parapinopsin, expressed separately in two different types of photoreceptor cells,  contribute to the generation of color opponency in the pineal ganglion cells. CONCLUSION: Our results indicate that the jawless vertebrate, lamprey, employs a system for color opponency that differes from that described previously in jawed vertebrates. From a physiological viewpoint, we propose an evolutionary insight, the emergence of pineal "one-cell system" from the ancestral "multiple (two)-cell system," showing the opposite evolutionary direction to that of the ocular color opponency.

    DOI: 10.1186/s12915-021-01121-1

    PubMed

  • Visual and nonvisual opsin genes of sharks and other nonosteichthyan vertebrates: Genomic exploration of underwater photoreception Reviewed

    Yamaguchi Kazuaki, Koyanagi Mitsumasa, Kuraku Shigehiro

    JOURNAL OF EVOLUTIONARY BIOLOGY   34 ( 6 )   968 - 976   2021.06( ISSN:1010-061X

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    Vision of sharks embraces various biological and ecological themes ranging from predation and adaptation to deep-sea life. However, behavioural and genetic studies have been limited by their elusive lifestyles, repeatedly reported declines of wild populations, and their unique life-history traits including low fecundity and enhanced longevity. Sharks have also not been actively studied on the cellular and molecular levels, because of additional difficulties in cell culture, tissue collection and genome sequencing. A recent study circumvented some of these obstacles by means of genome informatics thereby portrayed the variation of visual opsin gene repertoires among elasmobranchs (sharks and rays) and spectral shifts of the rhodopsin pigment. Comprehensive surveys in whole-genome sequences are also revealing the repertoires of nonvisual opsins with unknown functions. This review is aimed to summarize existing studies on shark opsins with an emphasis on genomic investigation of gene repertoires and to provide insights into the better understanding of underwater ecology of marine megafauna with in vitro experimentation.

    DOI: 10.1111/jeb.13730

    PubMed

  • Functional identification of an opsin kinase underlying inactivation of the pineal bistable opsin parapinopsin in zebrafish Reviewed

    Shen Baoguo, Wada Seiji, Nishioka Haruka, Nagata Takashi, Kawano-Yamashita Emi, Koyanagi Mitsumasa, Terakita Akihisa

    ZOOLOGICAL LETTERS   7 ( 1 )   2021.02( ISSN:2056-306X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40851-021-00171-1

  • Optogenetic Potentials of Diverse Animal Opsins: Parapinopsin, Peropsin, LWS Bistable Opsin Reviewed

    Koyanagi Mitsumasa, Saito Tomoka, Wada Seiji, Nagata Takashi, Kawano-Yamashita Emi, Terakita Akihisa

    OPTOGENETICS: LIGHT-SENSING PROTEINS AND THEIR APPLICATIONS IN NEUROSCIENCE AND BEYOND, 2ND EDITION   1293   141 - 151   2021.01( ISBN:978-981-15-8762-7

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/978-981-15-8763-4_8

  • From extraocular photoreception to pigment movement regulation: a new control mechanism of the lanternshark luminescence Reviewed

    Duchatelet Laurent, Sugihara Tomohiro, Delroisse Jerome, Koyanagi Mitsumasa, Rezsohazy Rene, Terakita Akihisa, Mallefet Jerome

    SCIENTIFIC REPORTS   10 ( 1 )   10195 - 10195   2020.06( ISSN:2045-2322

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    The velvet belly lanternshark, Etmopterus spinax, uses counterillumination to disappear in the surrounding blue light of its marine environment. This shark displays hormonally controlled bioluminescence in which melatonin (MT) and prolactin (PRL) trigger light emission, while α-melanocyte-stimulating hormone (α-MSH) and adrenocorticotropic hormone (ACTH) play an inhibitory role. The extraocular encephalopsin (Es-Opn3) was also hypothesized to act as a luminescence regulator. The majority of these compounds (MT, α-MSH, ACTH, opsin) are members of the rapid physiological colour change that regulates the pigment motion within chromatophores in metazoans. Interestingly, the lanternshark photophore comprises a specific iris-like structure (ILS), partially composed of melanophore-like cells, serving as a photophore shutter. Here, we investigated the role of (i) Es-Opn3 and (ii) actors involved in both MT and α-MSH/ACTH pathways on the shark bioluminescence and ILS cell pigment motions. Our results reveal the implication of Es-Opn3, MT, inositol triphosphate (IP3), intracellular calcium, calcium-dependent calmodulin and dynein in the ILS cell pigment aggregation. Conversely, our results highlighted the implication of the α-MSH/ACTH pathway, involving kinesin, in the dispersion of the ILS cell pigment. The lanternshark luminescence then appears to be controlled by the balanced bidirectional motion of ILS cell pigments within the photophore. This suggests a functional link between photoreception and photoemission in the photogenic tissue of lanternsharks and gives precious insights into the bioluminescence control of these organisms.

    DOI: 10.1038/s41598-020-67287-w

    PubMed

  • The non-visual opsins expressed in deep brain neurons projecting to the retina in lampreys Reviewed

    Kawano-Yamashita Emi, Koyanagi Mitsumasa, Wada Seiji, Saito Tomoka, Sugihara Tomohiro, Tamotsu Satoshi, Terakita Akihisa

    SCIENTIFIC REPORTS   10 ( 1 )   9669 - 9669   2020.06( ISSN:2045-2322

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    Publishing type:Research paper (scientific journal)  

    In lower vertebrates, brain photoreceptor cells express vertebrate-specific non-visual opsins. We previously revealed that a pineal-related organ-specific opsin, parapinopsin, is UV-sensitive and allows pineal wavelength discrimination in lampreys and teleost. The Australian pouched lamprey was recently reported as having two parapinopsin-related genes. We demonstrate that a parapinopsin-like opsin from the Japanese river lamprey exhibits different molecular properties and distribution than parapinopsin. This opsin activates Gi-type G protein in a mammalian cell culture assay in a light-dependent manner. Heterologous action spectroscopy revealed that the opsin forms a violet to blue-sensitive pigment. Interestingly, the opsin is co-localised with green-sensitive P-opsin in the cells of the M5 nucleus of Schober (M5NS) in the mesencephalon of the river and brook lamprey. Some opsins-containing cells of the river lamprey have cilia and others an axon projecting to the retina. The opsins of the brook lamprey are co-localised in the cilia of centrifugal neurons projecting to the retina, suggesting that cells expressing the parapinopsin-like opsin and P-opsin are sensitive to violet to green light. Moreover, we found neural connections between M5NS cells expressing the opsins and the retina. These findings suggest that the retinal activity might be modulated by brain photoreception.

    DOI: 10.1038/s41598-020-66679-2

    PubMed

  • Letter to the editor

    Kuraku Shigehiro, Yamaguchi Kazuaki, Terakita Akihisa, Koyanagi Mitsumasa

    VISUAL NEUROSCIENCE   37   E009   2020( ISSN:0952-5238

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1017/S0952523820000073

    PubMed

  • Spectral tuning mediated by helix III in butterfly long wavelength-sensitive visual opsins revealed by heterologous action spectroscopy Reviewed

    Saito Tomoka, Koyanagi Mitsumasa, Sugihara Tomohiro, Nagata Takashi, Arikawa Kentaro, Terakita Akihisa

    ZOOLOGICAL LETTERS   5 ( 1 )   2019.12( ISSN:2056-306X

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1186/s40851-019-0150-2

  • Co-expression of opsins in the eye photoreceptor cells of the terrestrial slug Limax valentianus Reviewed

    Matsuo Ryota, Koyanagi Mitsumasa, Nagata Akane, Matsuo Yuko

    JOURNAL OF COMPARATIVE NEUROLOGY   2019.06( ISSN:0021-9967

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1002/cne.24732

  • The counterion-retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation Reviewed International coauthorship

    Nagata Takashi, Koyanagi Mitsumasa, Tsukamoto Hisao, Mutt Eshita, Schertler Gebhard F. X., Deupi Xavier, Terakita Akihisa

    COMMUNICATIONS BIOLOGY   2   2019.05

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/s42003-019-0409-3

  • The Two-Photon Reversible Reaction of the Bistable Jumping Spider Rhodopsin-1. Reviewed International coauthorship

    Ehrenberg D, Varma N, Deupi X, Koyanagi M, Terakita A, Schertler GFX, Heberle J, Lesca E

    Biophysical journal   116 ( 7 )   1248 - 1258   2019.04( ISSN:0006-3495

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.bpj.2019.02.025

    PubMed

  • Shark genomes provide insights into elasmobranch evolution and the origin of vertebrates Reviewed

    Hara Yuichiro, Yamaguchi Kazuaki, Onimaru Koh, Kadota Mitsutaka, Koyanagi Mitsumasa, Keeley Sean D., Tatsumi Kaori, Tanaka Kaori, Motone Fumio, Kageyama Yuka, Nozu Ryo, Adachi Noritaka, Nishimura Osamu, Nakagawa Reiko, Tanegashima Chiharu, Kiyatake Itsuki, Matsumoto Rui, Murakumo Kiyomi, Nishida Kiyonori, Terakita Akihisa, Kuratani Shigeru, Sato Keiichi, Hyodo Susumu, Kuraku Shigehiro

    NATURE ECOLOGY & EVOLUTION   2 ( 11 )   1761 - 1771   2018.11( ISSN:2397-334X

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/s41559-018-0673-5

  • Color opponency with a single kind of bistable opsin in the zebrafish pineal organ Reviewed

    Wada Seiji, Shen Baoguo, Kawano-Yamashita Emi, Nagata Takashi, Hibi Masahiko, Tamotsu Satoshi, Koyanagi Mitsumasa, Terakita Akihisa

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   115 ( 44 )   11310 - 11315   2018.10( ISSN:0027-8424

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1073/pnas.1802592115

  • Convergent evolution of tertiary structure in rhodopsin visual proteins from vertebrates and box jellyfish Reviewed International coauthorship

    Gerrard Elliot, Mutt Eshita, Nagata Takashi, Koyanagi Mitsumasa, Flock Tilman, Lesca Elena, Schertler Gebhard F. X., Terakita Akihisa, Deupi Xavier, Lucas Robert J.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   115 ( 24 )   6201 - 6206   2018.06( ISSN:0027-8424

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1073/pnas.1721333115

  • An all-trans-retinal-binding opsin peropsin as a potential dark-active and light-inactivated G protein-coupled receptor Reviewed International coauthorship

    Nagata Takashi, Koyanagi Mitsumasa, Lucas Robert, Terakita Akihisa

    SCIENTIFIC REPORTS   8   2018.02( ISSN:2045-2322

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/s41598-018-21946-1

  • Expression and light-dependent translocation of beta-arrestin in the visual system of the terrestrial slug Limax valentianus Reviewed

    Matsuo Ryota, Takatori Yuka, Hamada Shun, Koyanagi Mitsumasa, Matsuo Yuko

    JOURNAL OF EXPERIMENTAL BIOLOGY   220 ( 18 )   3301 - 3314   2017.09( ISSN:0022-0949

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1242/jeb.162701

  • Vertebrate Bistable Pigment Parapinopsin: Implications for Emergence of Visual Signaling and Neofunctionalization of Non-visual Pigment Invited Reviewed

    Koyanagi Mitsumasa, Kawano-Yamashita Emi, Wada Seiji, Terakita Akihisa

    FRONTIERS IN ECOLOGY AND EVOLUTION   5   2017.04( ISSN:2296-701X

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.3389/fevo.2017.00023

  • Absorption Characteristics of Vertebrate Non-Visual Opsin, Opn3 Reviewed International coauthorship

    Sugihara Tomohiro, Nagata Takashi, Mason Benjamin, Koyanagi Mitsumasa, Terakita Akihisa

    PLOS ONE   11 ( 8 )   2016.08( ISSN:1932-6203

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1371/journal.pone.0161215

  • Coral opsins: photosensitivity and partial characterization of five opsins from Acropora millepora Reviewed

    Mason B. M., Miller D. J., Koyanagi M., Terakita A.

    INTEGRATIVE AND COMPARATIVE BIOLOGY   56   E139 - E139   2016.03( ISSN:1540-7063

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  • Retinal Attachment Instability Is Diversified among Mammalian Melanopsins Reviewed International coauthorship

    Tsukamoto Hisao, Kubo Yoshihiro, Farrens David L., Koyanagi Mitsumasa, Terakita Akihisa, Furutani Yuji

    JOURNAL OF BIOLOGICAL CHEMISTRY   290 ( 45 )   27176 - 27187   2015.11( ISSN:0021-9258

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    DOI: 10.1074/jbc.M115.666305

  • Activation of Transducin by Bistable Pigment Parapinopsin in the Pineal Organ of Lower Vertebrates Reviewed

    Kawano-Yamashita Emi, Koyanagi Mitsumasa, Wada Seiji, Tsukamoto Hisao, Nagata Takashi, Terakita Akihisa

    PLOS ONE   10 ( 10 )   2015.10( ISSN:1932-6203

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    DOI: 10.1371/journal.pone.0141280

  • Diversification of non-visual photopigment parapinopsin in spectral sensitivity for diverse pineal functions Reviewed

    Koyanagi Mitsumasa, Wada Seiji, Kawano-Yamashita Emi, Hara Yuichiro, Kuraku Shigehiro, Kosaka Shigeaki, Kawakami Koichi, Tamotsu Satoshi, Tsukamoto Hisao, Shichida Yoshinori, Terakita Akihisa

    BMC BIOLOGY   13   2015.09( ISSN:1741-7007

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    DOI: 10.1186/s12915-015-0174-9

  • Green-sensitive opsin is the photoreceptor for photic entrainment of an insect circadian clock Reviewed

    Komada Sayaka, Kamae Yuichi, Koyanagi Mitsumasa, Tatewaki Kousuke, Hassaneen Ehab, Saifullah A. S. M., Yoshii Taishi, Terakita Akihisa, Tomioka Kenji

    ZOOLOGICAL LETTERS   1   2015.02( ISSN:2056-306X

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    DOI: 10.1186/s40851-015-0011-6

  • Optogenetic potentials of diverse animal opsins Reviewed

    Akihisa Terakita, Takashi Nagata, Tomohiro Sugihara, Mitsumasa Koyanagi

    Springer Japan Optogenetics: Light-Sensing Proteins and their Applications   77 - 88   2015.01

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    Animal opsin-based pigments are light-activated G-protein-coupled receptors (GPCRs), which drive signal transduction cascades via G proteins. Thousands of animal opsins have been identified, and molecular phylogenetic and biochemical analyses have revealed that opsin-based pigments have basically diversified in selective activation of G proteins (Gs, Gq, Gi, Go, and transducin). Here, we discuss the optogenetic potentials of diverse animal opsins, particularly Gq-coupled spider opsin, Gs-coupled jellyfish opsin, and Gi/Go-coupled mosquito opsin 3 (Opn3). After absorbing light, these purified opsin-based pigments do not release the chromophore retinal, indicating the bleach-resistant nature of their photoproducts. In addition, unlike vertebrate visual opsin-based pigments that have been conventionally used for optogenetic applications, the stable photoproducts of spider opsin- and mosquito Opn3-based pigments revert to their original dark states upon subsequent light absorption, which indicates their photoregeneration ability. Mammalian cultured cells that express spider opsin exhibit light-induced increases in Ca&lt
    sup&gt
    2+&lt
    /sup&gt
    levels, and jellyfish opsin- and mosquito Opn3-expressing cells exhibit light-dependent increases and decreases in cyclic adenosine monophosphate (cAMP) levels, respectively. These findings indicate that these pigments control different second messengers, Ca&lt
    sup&gt
    2+&lt
    /sup&gt
    and cAMP, in mammalian cultured cells, suggesting that these bleach-resistant opsins have an optogenetic potential.

    DOI: 10.1007/978-4-431-55516-2_6

  • 増大特集 生命動態システム科学 Ⅲ.合成生物学 4.オプトジェネティクス (4)細胞内情報伝達分子の時空間的に精密な制御 Reviewed

    小柳 光正

    生体の科学   65 ( 5 )   522 - 523   2014.10( ISSN:03709531

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    DOI: 10.11477/mf.2425200070

  • Distribution of Mammalian-Like Melanopsin in Cyclostome Retinas Exhibiting a Different Extent of Visual Functions Reviewed

    Sun Lanfang, Kawano-Yamashita Emi, Nagata Takashi, Tsukamoto Hisao, Furutani Yuji, Koyanagi Mitsumasa, Terakita Akihisa

    PLOS ONE   9 ( 9 )   2014.09( ISSN:1932-6203

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    DOI: 10.1371/journal.pone.0108209

  • Diversity of animal opsin-based pigments and their optogenetic potential Reviewed

    Koyanagi Mitsumasa, Terakita Akihisa

    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS   1837 ( 5 )   710 - 716   2014.05( ISSN:0005-2728

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    DOI: 10.1016/j.bbabio.2013.09.003

  • The evolution and diversity of pineal and parapineal photopigments Reviewed

    Emi Kawano-Yamashita, Mitsumasa Koyanagi, Akihisa Terakita

    Springer US Evolution of Visual and Non-Visual Pigments   1 - 21   2014.01

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    Pineal and related organs are major extraocular photoreceptors in nonmammalian vertebrates. The pineal organ contains several types of photoreceptor cells, which contribute to regulating light-dependent melatonin secretion and the neural light response, including irradiance detection and wavelength discrimination. Visual opsins and pineal-specific opsins have been identified from the pineal and related organs in a wide variety of non-mammalian vertebrates. Pinopsin and parapinopsin are key opsins for understanding melatonin secretion in the chicken pineal organ and wavelength discrimination in the lamprey pineal organ, respectively. Interestingly, parapinopsin has the molecular characteristics of both vertebrate and invertebrate opsin-based pigments, making it an important photopigment for understanding the molecular evolution of vertebrate visual opsins. In this chapter, we discuss the opsin-based pigments functioning in the pineal and related organs with a focus on parapinopsin.

    DOI: 10.1007/978-1-4614-4355-1_1

  • "非視覚"型光受容タンパク質Opn3とそのGPCR研究への応用 Reviewed

    小柳 光正, 寺北 明久

    公益社団法人 日本薬学会 ファルマシア   50 ( 9 )   893 - 895   2014( ISSN:0014-8601

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    動物は光を視覚のみならず概日リズムの光同調などの視覚以外(非視覚)の役割にも利用している.動物の中には光を眼に限らず脳や皮膚などでも受容するものもいるが,ヒトを含むほ乳類では眼が唯一の光受容器官であると考えられてきた.ところが1999年に,視物質であるロドプシンに類似した新規の光受容タンパク質遺伝子(オプシン)がマウスの小脳で発現していることが報告され,この定説が覆る可能性が出てきた.<br>本稿では,この新規オプシンOpn3について私たちの最近の研究成果を中心に紹介するとともに,Opn3のGタンパク質共役型受容体(G protein‐coupled receptor:GPCR)研究への応用の可能性について述べたい.

    DOI: 10.14894/faruawpsj.50.9_893

    CiNii Article

  • 1P243 Analysis of molecular properties of various opsins by bioluminescence monitoring of second-messengers in cultured cells(18A. Photobiology:Vision & Photoreception,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014)) Reviewed

    Nagata Takashi, Sugihara Tomohiro, Koyanagi Mitsumasa, Terakita Akihisa

    Seibutsu Butsuri   54 ( 1 )   S181   2014

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    DOI: 10.2142/biophys.54.S181_3

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  • Homologs of vertebrate Opn3 potentially serve as a light sensor in nonphotoreceptive tissue Reviewed

    Koyanagi Mitsumasa, Takada Eiichiro, Nagata Takashi, Tsukamoto Hisao, Terakita Akihisa

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   110 ( 13 )   4998 - 5003   2013.03( ISSN:0027-8424

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1073/pnas.1219416110

  • 3P251 Molecular properties of animal bistable rhodopsins and their optogenetic potential(18A. Photobiology: Vision & Photoreception,Poster) Reviewed

    Sugihara Tomohiro, Koyanagi Mitsumasa, Terakita Akihisa

    Seibutsu Butsuri   53 ( 1 )   S253   2013

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    DOI: 10.2142/biophys.53.S253_4

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  • Expression of UV-Sensitive Parapinopsin in the Iguana Parietal Eyes and Its Implication in UV-Sensitivity in Vertebrate Pineal-Related Organs Reviewed

    Wada Seiji, Kawano-Yamashita Emi, Koyanagi Mitsumasa, Terakita Akihisa

    PLOS ONE   7 ( 6 )   2012.06( ISSN:1932-6203

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    DOI: 10.1371/journal.pone.0039003

  • Depth Perception from Image Defocus in a Jumping Spider Reviewed

    Nagata Takashi, Koyanagi Mitsumasa, Tsukamoto Hisao, Saeki Shinjiro, Isono Kunio, Shichida Yoshinori, Tokunaga Fumio, Kinoshita Michiyo, Arikawa Kentaro, Terakita Akihisa

    SCIENCE   335 ( 6067 )   469 - 471   2012.01( ISSN:0036-8075

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    DOI: 10.1126/science.1211667

  • 2PT190 1YS1015 A novel depth perception mechanism based on image defocus in a spider(The 50th Annual Meeting of the Biophysical Society of Japan,Early Research in Biophysics Award Candidate Presentations,Early Research in Biophysics Award) Reviewed

    Nagata Takashi, Koyanagi Mitsumasa, Tsukamoto Hisao, Saeki Shinjiro, Isono Kunio, Shichida Yoshinori, Tokunaga Fumio, Kinoshita Michiyo, Arikawa Kentaro, Terakita Akihisa

    Seibutsu Butsuri   52   S138   2012

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    DOI: 10.2142/biophys.52.S138_3

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  • Beta-Arrestin Functionally Regulates the Non-Bleaching Pigment Parapinopsin in Lamprey Pineal Reviewed

    Kawano-Yamashita Emi, Koyanagi Mitsumasa, Shichida Yoshinori, Oishi Tadashi, Tamotsu Satoshi, Terakita Akihisa

    PLOS ONE   6 ( 1 )   2011.01( ISSN:1932-6203

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    DOI: 10.1371/journal.pone.0016402

  • Diversity of opsin-based photopigment: insight into the evolution of photoreceptor cell and phototransduction cascade Reviewed

    Koyanagi Mitsumasa

    GENES & GENETIC SYSTEMS   85 ( 6 )   455 - 455   2010.12( ISSN:1341-7568

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  • Evolution and Mechanism of Spectral Tuning of Blue-Absorbing Visual Pigments in Butterflies Reviewed

    Wakakuwa Motohiro, Terakita Akihisa, Koyanagi Mitsumasa, Stavenga Doekele G., Shichida Yoshinori, Arikawa Kentaro

    PLOS ONE   5 ( 11 )   2010.11( ISSN:1932-6203

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    DOI: 10.1371/journal.pone.0015015

  • Identification and characterization of a protostome homologue of peropsin from a jumping spider Reviewed

    Nagata Takashi, Koyanagi Mitsumasa, Tsukamoto Hisao, Terakita Akihisa

    JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY   196 ( 1 )   51 - 59   2010.01( ISSN:0340-7594

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    DOI: 10.1007/s00359-009-0493-9

  • 3P275 ハエトリグモロドプシンの吸収スペクトル特性と奥行き知覚メカニズムとの関係の解析(光生物-視覚・光受容,第48回日本生物物理学会年会) Reviewed

    Nagata Takashi, Koyanagi Mitsumasa, Tsukamoto Hisao, Isono Kunio, Arikawa Kentaro, Terakita Akihisa

    一般社団法人 日本生物物理学会 生物物理   50 ( 2 )   2010( ISSN:0582-4052

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    DOI: 10.2142/biophys.50.S194_1

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  • The Magnitude of the Light-induced Conformational Change in Different Rhodopsins Correlates with Their Ability to Activate G Proteins Reviewed

    Tsukamoto Hisao, Farrens David L., Koyanagi Mitsumasa, Terakita Akihisa

    JOURNAL OF BIOLOGICAL CHEMISTRY   284 ( 31 )   20676 - 20683   2009.07( ISSN:0021-9258

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    DOI: 10.1074/jbc.M109.016212

  • 第4回アジア・オセアニア光生物学会議(AOCP)印象記 Reviewed

    小柳 光正

    日本比較生理生化学会 比較生理生化学   26 ( 2 )   72 - 74   2009.04( ISSN:09163786

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  • Identification and characterization of a visual pigment expressed in posterior median eyes of jumping spiders Reviewed

    Nagata Takashi, Koyanagi Mitsumasa, Isono Kunio, Yama-shita Shigeki, Tokunaga Fumio, Arikawa Kentaro, Terakita Akihisa

    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   151 ( 4 )   449 - 449   2008.12( ISSN:1096-4959

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    DOI: 10.1016/j.cbpb.2008.09.005

  • Jellyfish vision starts with cAMP signaling mediated by opsin-G(s) cascade Reviewed

    Koyanagi Mitsumasa, Takano Kosuke, Tsukamoto Hisao, Ohtsu Kohzoh, Tokunaga Fumio, Terakita Akihisa

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   105 ( 40 )   15576 - 15580   2008.10( ISSN:0027-8424

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1073/pnas.0806215105

  • Expression and comparative characterization of Gq-coupled invertebrate visual pigments and melanopsin Reviewed

    Terakita Akihisa, Tsukamoto Hisao, Koyanagi Mitsumasa, Sugahara Michio, Yamashita Takahiro, Shichida Yoshinori

    JOURNAL OF NEUROCHEMISTRY   105 ( 3 )   883 - 890   2008.05( ISSN:0022-3042

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    DOI: 10.1111/j.1471-4159.2007.05184.x

  • Relationships between the diversity of the opsins and that of photoreceptive systems Reviewed

    KOYANAGI Mitsumasa

    THE JAPANESE SOCIETY FOR COMPARATIVE PHYSIOLOGY AND BIOCHEMISTRY, Dobutsu seiri   25 ( 2 )   50 - 57   2008.04( ISSN:09163786

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    Animals use light information not only for vision but for non-visual functions, such as circadian entrainment and pupillary light response. Opsins, underling molecules of these photoreceptions, are diversified. We aimed to reveal relationships between the diversity of opsins and that of photoreceptive systems by biochemical and spectroscopic analyses of varied opsins. We cloned seven opsins from amphioxus (<I>Branchiostoma belcheri</I>) and succeeded in functional expression of amphioxus homologues of the Go-coupled opsin and the perospin, whose molecular properties have been largely unknown, in HEK293 cells. Spectroscopic analyses revealed that the Go-coupled opsin and the peropsin bind 11-cis and all-trans retinals, respectively as a chromophore. The results strongly suggest that the physiological function of peropsin is a retinal photoisomerase, while 11-cis configuration is necessary for the Go-coupled opsin. We also demonstrated that the amphioxus homologue of melanopsin, which functions as the circadian photopigment in the photosensitive retinal ganglion cells in mammals, is considerably similar to invertebrate visual pigments in biochemical and photochemical properties for the first time. This finding suggested the evolutionary linkage between invertebrate rhabdomeric visual cells and vertebrate photosensitive retinal ganglion cells. We also showed that the parapinopsin is the UV pigment in the lamprey (<I>Lethenteron japonica</I>) pineal and is the bistable pigment having photointerconvertible two stable states, that is, the original and the G-protein-activating states. The bistable nature of the parapinopsin can account for the photorecovery of the pineal UV-sensitivity by background green light. Our approach could provide cues to understand the evolution of physiological functions.

    DOI: 10.3330/hikakuseiriseika.25.50

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  • Molecular evolution of arthropod color vision deduced from multiple opsin genes of jumping spiders Reviewed

    Koyanagi Mitsumasa, Nagata Takashi, Katoh Kazutaka, Yamashita Shigeki, Tokunaga Fumio

    JOURNAL OF MOLECULAR EVOLUTION   66 ( 2 )   130 - 137   2008.02( ISSN:0022-2844

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    DOI: 10.1007/s00239-008-9065-9

  • Gq-coupled rhodopsin subfamily composed of invertebrate visual pigment and melanopsin Reviewed

    Koyanagi Mitsumasa, Terakita Akihisa

    PHOTOCHEMISTRY AND PHOTOBIOLOGY   84 ( 4 )   1024 - 1030   2008( ISSN:0031-8655

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    DOI: 10.1111/j.1751-1097.2008.00369.x

  • Molecular evolution of arthropod color vision deduced from multiple opsin genes of jumping spiders

    Journal of Molecular Evolution / Springer-Verlag New York Inc.   66   130 - 137   2008

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  • Immunohistochemical characterization of a parapinopsin-containing photoreceptor cell involved in the ultraviolet/green discrimination in the pineal organ of the river lamprey Lethenteron japonicum Reviewed

    Kawano-Yamashita Emi, Terakita Akihisa, Koyanagi Mitsumasa, Shichida Yoshinori, Oishi Tadashi, Tamotsu Satoshi

    JOURNAL OF EXPERIMENTAL BIOLOGY   210 ( 21 )   3821 - 3829   2007.11( ISSN:0022-0949

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    DOI: 10.1242/jeb.007161

  • A relationship between visual pigments and color vision in jumping spiders Reviewed

    Nagata Takashi, Koyanagi Mitsumasa, Yamashita Shigeki, Tokunaga Fumio, Terakita Akihisa

    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   148 ( 3 )   344 - 345   2007.11( ISSN:1096-4959

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    DOI: 10.1016/j.cbpb.2007.07.042

  • Molecular basis for the photoreception of a primitive animal, box jellyfish Reviewed

    Koyanagi Mitsumasa, Takano Kousuke, Tokunaga Fumio, Otsu Kozo, Terakita Akihisa

    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   148 ( 3 )   345 - 345   2007.11( ISSN:1096-4959

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    DOI: 10.1016/j.cbpb.2007.07.044

  • Comparative biochemical analysis of invertebrate visual pigments and melanopsin Reviewed

    Terakita Akihisa, Tsukamoto Hisao, Koyanagi Mitsumasa, Sugahara Michio, Yamashita Takahiro, Shichida Yoshinori

    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   148 ( 3 )   345 - 345   2007.11( ISSN:1096-4959

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    DOI: 10.1016/j.cbpb.2007.07.043

  • 2P334 無脊椎動物ロドプシンにおけるレチナールシッフ塩基周辺のアミノ酸相互作用についての変異体解析(光生物学(視覚と光受容),口頭発表,第45回日本生物物理学会年会) Reviewed

    永田 崇, 塚本 寿夫, 小柳 光正, 寺北 明久

    一般社団法人 日本生物物理学会 生物物理   47 ( 0 )   2007( ISSN:0582-4052

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    DOI: 10.2142/biophys.47.S196_3

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  • Immunohistochemical characterization of a parapinopsin-containing photoreceptor cell involved in the ultraviolet/green discrimination in the pineal organ of the river lamprey Lethenteron japonicum.

    Journal of Experimental Biology / The Company of Biologists   210   3821 - 3829   2007

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  • 2P335 Detection of structural changes involved in activation of diverged rhodopsins using site-directed fluorescence labeling(Photobiology-vision and photoreception,Oral Presentations) Reviewed

    Tsukamoto Hisao, Koyanagi Mitsumasa, Terakita Akihisa

    Seibutsu Butsuri   47   S196   2007

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    DOI: 10.2142/biophys.47.S196_4

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  • Comparative analyses of melanopsin with invertebrate visual pigmetns Reviewed

    Terakita Akihisa, Koyanagi Mitsumasa, Tsukamoto Hisao, Shichida Yoshinori

    ZOOLOGICAL SCIENCE   23 ( 12 )   1198 - 1198   2006.12( ISSN:0289-0003

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  • Diversity of the vertebrate non-visual pigment parapinopsins Reviewed

    Koyanagi Mitsumasa, Terakita Akihisa, Tsukamoto Hisao, Terakita Akihisa

    ZOOLOGICAL SCIENCE   23 ( 12 )   1198 - 1198   2006.12( ISSN:0289-0003

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  • Relationships between the diversity of opsins and that of photoreceptive systems Reviewed

    Koyanagi Mitsumasa

    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   145 ( 3-4 )   402 - 402   2006( ISSN:1096-4959

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    DOI: 10.1016/j.cbpb.2006.10.006

  • Expression analyses of visual pigments in the four-layered retina of jumping spider Reviewed

    Nagata Takashi, Koyanagi Mitsumasa, Yamashita Shigeki, Tokunaga Fumio

    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   145 ( 3-4 )   408 - 408   2006( ISSN:1096-4959

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.cbpb.2006.10.022

  • Diversity of non-visual pigment parapinopsin in lower vertebrates Reviewed

    Terakita Akihisa, Koyanagi Mitsumasa, Shichida Yoshinori

    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY   145 ( 3-4 )   421 - 422   2006( ISSN:1096-4959

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.cbpb.2006.10.086

  • 1P431 Mutational analyses of active state of bistable rhodopsins(17. Light driven system,Poster Session,Abstract,Meeting Program of EABS &BSJ 2006) Reviewed

    Tsukamoto Hisao, Terakita Akihisa, Koyanagi Mitsumasa, Shichida Yoshinori

    一般社団法人 日本生物物理学会 生物物理   46 ( 2 )   2006( ISSN:0582-4052

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    DOI: 10.2142/biophys.46.S254_3

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  • Cephalochordate melanopsin: evolutionary linkage between invertebrate visual cells and vertebrate photosensitive retinal ganglion cells. Reviewed

    Koyanagi M, Kubokawa K, Tsukamoto H, Shichida Y, Terakita A

    Current biology : CB   15 ( 11 )   1065 - 1069   2005.06( ISSN:0960-9822

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    DOI: 10.1016/j.cub.2005.04.063

    PubMed

  • Cephalochordate melanopsin: Evolutionary linkage between invertebrate visual cells and vertebrate photosensitive retinal ganglion cells.

    Curr. Biol.   15 ( 11 )   1065 - 1069   2005

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  • 1P278 Comparative analyses of cephalochordate melanopsin with Gq-coupled invertebrate rhodopsin Reviewed

    Terakita A., Koyanagi M., Tsukamoto H., Kubokawa K., Shichida Y.

    Seibutsu Butsuri   45   S101   2005

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    DOI: 10.2142/biophys.45.S101_2

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  • Counterion displacement in the molecular evolution of the rhodopsin family.

    Nat. Struct. Mol. Biol.   3   284 - 289   2004

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  • Bistable UV pigment in the lamprey pineal.

    Proc. Natl. Acad. Sci. USA   101 ( 17 )   6687 - 6691   2004

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  • Amphioxus homologs of Go-coupled rhodopsin and peropsin having 11-cis- and all-trans-retinals as their chromophores.

    FEBS Lett.   531 ( 3 )   525 - 528   2002

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  • Extensive gene duplication in the early evolution of animals before parazoan-eumetazoan split demonstrated by G proteins and protein tyrosine kinases from sponge and hydra.

    J. Mol. Evol.   48   646 - 653   1999

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    Publishing type:Research paper (scientific journal)  

  • Ancient gene duplication and domain shuffling in the animal cyclic nucleotide phosphodiesterase family.

    FEBS Lett.   436   323 - 328   1998

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    Publishing type:Research paper (scientific journal)  

  • Phospholipase C cDNAs from sponge and hydra: antiquity of genes involved in the inositol phospholipid signaling pathway.

    FEBS Lett.   439   66 - 70   1998

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    Publishing type:Research paper (scientific journal)  

  • Sponge Pax cDNA related to Pax-2/5/8 and ancient gene duplications in the Pax family.

    J. Mol. Evol.   47   640 - 648   1998

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    Publishing type:Research paper (scientific journal)  

  • Intermittent divergence of the protein tyrosine kinase family during animal evolution.

    FEBS Lett.   412   540 - 546   1997

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    Publishing type:Research paper (scientific journal)  

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Books and Other Publications

  • 感覚と応答の生物学 Reviewed

    小柳 光正( Role: Joint author ,  第3章、第4章)

    放送大学教育振興会  2023.03 

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    Book type:Textbook, survey, introduction

  • 光と生命の事典

    日本光生物学協会光と生命の事典編集委員会, 日本光生物学協会( Role: Joint author ,  No.127)

    朝倉書店  2016  ( ISBN:9784254171617

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    Book type:Dictionary, encyclopedia Participation form:Corresponding Author

  • Optogenetics : light-sensing proteins and their applications

    八尾 寛, 神取 秀樹, 小泉 周( Role: Joint author ,  p77-88)

    Springer  2015  ( ISBN:9784431555155

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    Book type:Scholarly book

  • Evolution of visual and non-visual pigments

    Hunt David M.( Role: Joint author ,  p1-21)

    Springer  2014  ( ISBN:9781461443544

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    Book type:Scholarly book

  • ウニ,ナマコから脊椎動物へ

    針山 孝彦, 小柳 光正, 嬉 正勝, 妹尾 圭司, 小泉 修, 日本比較生理生化学会( Role: Sole author)

    共立出版  2012  ( ISBN:9784320057203

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    Book type:Scholarly book

    CiNii Books

  • 昆虫とクモの仲間

    針山 孝彦, 小柳 光正, 嬉 正勝, 妹尾 圭司, 小泉 修, 日本比較生理生化学会( Role: Joint editor)

    共立出版  2012  ( ISBN:9784320057197

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  • ゾウリムシ,ヒドラ,貝,エビなど

    針山 孝彦, 小柳 光正, 嬉 正勝, 妹尾 圭司, 小泉 修, 日本比較生理生化学会( Role: Joint editor)

    共立出版  2012  ( ISBN:9784320057180

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    Book type:Scholarly book

  • ウニ,ナマコから脊椎動物へ

    針山 孝彦, 小柳 光正, 嬉 正勝, 妹尾 圭司, 小泉 修, 日本比較生理生化学会( Role: Joint editor)

    共立出版  2012  ( ISBN:9784320057203

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    Book type:Scholarly book

  • 昆虫とクモの仲間

    針山 孝彦, 小柳 光正, 嬉 正勝, 妹尾 圭司, 小泉 修, 日本比較生理生化学会( Role: Sole author)

    共立出版  2012  ( ISBN:9784320057197

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    Book type:Scholarly book

    CiNii Books

  • ゾウリムシ,ヒドラ,貝,エビなど

    針山 孝彦, 小柳 光正, 嬉 正勝, 妹尾 圭司, 小泉 修, 日本比較生理生化学会( Role: Sole author)

    共立出版  2012  ( ISBN:9784320057180

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    Book type:Scholarly book

    CiNii Books

  • 進化 : 分子・個体・生態系

    Barton Nicholas H., Briggs D. E. G., Eisen Jonathan A., Goldstein David B., Patel Nipam, 宮田 隆, 星山 大介( Role: Joint translator ,  第2章)

    メディカル・サイエンス・インターナショナル  2009  ( ISBN:9784895926218

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    Book type:Scholarly book

  • 見える光,見えない光 : 動物と光のかかわり

    日本比較生理生化学会, 寺北 明久, 蟻川 謙太郎( Role: Joint author ,  光センサーの進化)

    共立出版  2009  ( ISBN:9784320056879

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    Responsible for pages:p22-31   Book type:Scholarly book

  • 生きものなんでも相談

    日本動物学会( Role: Joint author ,  p35)

    大阪公立大学共同出版会  2009  ( ISBN:9784901409605

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    Book type:Scholarly book

  • 昆虫ミメティックス : 昆虫の設計に学ぶ

    下澤 楯夫, 針山 孝彦( Role: Joint translator ,  p208-214)

    エヌ・ティー・エス  2008  ( ISBN:9784860431976

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    Book type:Scholarly book

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MISC

  • 動物の最初の視覚系を探る Invited

    小柳 光正

    細胞工学   34 ( 1 )   2015

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  • 【生命動態システム科学】 合成生物学 オプトジェネティクス 細胞内情報伝達分子の時空間的に精密な制御 Reviewed

    小柳 光正

    (公財)金原一郎記念医学医療振興財団 生体の科学   65 ( 5 )   522 - 523   2014.10( ISSN:0370-9531

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  • 【GPCR研究の熱い潮流】 "非視覚"型光受容タンパク質Opn3とそのGPCR研究への応用 Reviewed

    小柳 光正, 寺北 明久

    (公社)日本薬学会 ファルマシア   50 ( 9 )   893 - 895   2014.09( ISSN:0014-8601

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  • “非視覚”型光受容タンパク質Opn3とそのGPCR研究への応用 Reviewed

    小柳 光正、寺北 明久

    ファルマシア   50 ( 9 )   2014

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    Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Kind of work:Single Work  

  • 細胞内情報伝達分子の時空間的に精密な制御 Invited

    小柳 光正

    生体の科学   65 ( 5 )   2014

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  • ハエトリグモはピンぼけ像を使って奥行きを知覚する Invited

    小柳 光正、寺北 明久

    生物の科学 遺伝   67 ( 1 )   101 - 106   2013.01

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  • クモに学ぶピンぼけ量にもとづく距離測定システム Invited

    小柳 光正、寺北 明久

    工業材料   11月号   48 - 52   2013

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    Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Kind of work:Single Work  

  • Evolution and diversity of opsins Reviewed

    A. Terakita, E. Kawano-Yamashita, M. Koyanagi

    WIREs Membrane Transport and Signaling   1   104 - 111   2012

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  • ピンボケ度で距離を知るハエトリグモの目 Invited

    小柳 光正

    natureダイジェスト   6月号   22 - 24   2012

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  • ピンぼけ像を利用したハエトリグモの奥行きの知覚 Invited

    永田 崇、小柳 光正、寺北 明久

    ライフサイエンス 新着論文レビュー   2012

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  • 視覚の分子基盤の進化・多様性:動物の多様なロドプシンとシグナル伝達系の比較から何がわかるか Invited

    小柳 光正、寺北 明久

    細胞工学   30 ( 3 )   288 - 294   2011.03

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  • 視覚の分子基盤の進化・多様性 動物の多様なロドプシンとシグナル伝達系の比較から何がわかるか Reviewed

    小柳 光正, 寺北 明久

    (株)学研メディカル秀潤社 細胞工学   30 ( 3 )   288 - 294   2011.02( ISSN:0287-3796

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    著者等は、多様なロドプシン類の機能に関わる分子特性の解明に成功した。ロドプシン類が機能する光受容細胞の進化や脊椎動物の視覚の進化に関する下記の知見を紹介した。1)ロドプシン類の多様性、2)動物の多様な光受容細胞、3)感桿型光受容細胞と光感受性神経節細胞との進化的つながり、4)二胚葉動物の視細胞に存在する新奇光シグナル伝達系、5)対イオンの変位と脊椎動物視物質の進化。

  • Molecular Evolution and Functional Diversity of Opsin-Based Photopigments Reviewed

    T. Nagata, M. Koyanagi, A. Terakita

    Photobiological Sciences Online   2010

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  • オプシンファミリーの分子進化と機能多様性 Invited Reviewed

    小柳 光正

    比較生理生化学   25   50 - 57   2008

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  • Investigation of the non-visual pigment parapinopsins in lower vertebrates

    Akihisa Terakita, Mitsumasa Koyanagi, Yoshinori Shichida

    ZOOLOGICAL SCIENCE   22 ( 12 )   1474 - 1474   2005.12( ISSN:0289-0003

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    Publishing type:Research paper, summary (international conference)  

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Presentations

  • Analyses of light-dependent behavior involving pineal photoreceptions using zebrafish larvae. Domestic conference

    Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    2022.11 

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  • Investigation of spectroscopic properties and spectral tuning of anthozoan opsins in a reef-building coral Domestic conference

    Sakai, Y, M. Koyanagi, A. Terakita

    2022.11 

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    Presentation type:Oral presentation (general)  

  • Investigation of neural activity changes derived from extraocular photoreception in the whole brain of larval zebrafish by calcium imaging Domestic conference

    2022.11 

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    Presentation type:Oral presentation (general)  

  • Spectroscopic and immunohistochemical characterization of a mammalian non-visual opsin Opn3 Domestic conference

    2022.11 

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  • Reproduction of early processes in the evolution of photosensory system by short-term selection of C. elegans optogenetically rendered photosensitive Domestic conference

    Ryu Sato, Takashi Nagata, Taizo Kawano, Shinichi Miyazaki, Yu Hayashi, Akihisa Terakita, Mitsumasa Koyanagi

    2022.11 

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    Presentation type:Oral presentation (general)  

  • Analysis of light-dependent behaviors with a pineal opsin, parapinopsin-mutant zebrafish Domestic conference

    2022.11 

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    Presentation type:Oral presentation (general)  

  • Diversity of animal opsins and molecular property-based optical control of GPCR signaling by bistable opsins Invited International conference

    Mitsumasa Koyanagi

    2022.11 

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    Presentation type:Oral presentation (invited, special)  

  • Visualization of neural pathways based on the molecular property of a pineal opsin and its contribution to light-dependent behavior using zebrafish larvae International conference

    Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    2022.11 

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  • Investigation of bioluminescence-based opsin activation for analyzing biological function of non-visual opsins International conference

    Makoto Iwasaki, Seiji Wada, Takashi Nagata, Tomohiro Sugihara, Mitsumasa Koyanagi, Akihisa Terakita

    2022.10 

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  • Investigation of spectroscopic properties and spectral tuning of anthozoan opsins in a reef-building coral International conference

    Sakai, Y, M. Koyanagi, A. Terakita

    19th International Conference on Retinal Proteins  2022.10 

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  • Investigation of neural activity changes derived from extraocular photoreception in the whole brain of larval zebrafish by calcium imaging. International conference

    2022.10 

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    Presentation type:Oral presentation (general)  

  • Investigation of the spectral tuning of the jumping spider rhodopsin that underlies the depth perception from image defocus International conference

    Ryu Sato, Takashi Nagata, Akihisa Terakita, Mitsumasa Koyanagi

    2022.10 

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  • Development of bistable optical control tools based on a Gs-coupled opsin Domestic conference

    Akinari Sakayori, Yusuke Sakai, Mitsumasa Koyanagi, Akihisa Terakita, Hisao Tsukamoto

    2022.09 

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  • Spectroscopic study of photoisomerization mechanism of Jellyfish Opsin having counterion at different position Domestic conference

    Shino Inukai, Kota Katayama, Mitsumasa Koyanagi, Akihisa Tereakita, Hideki Kandori

    2022.09 

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  • Investigation of spectral properties and spectral tuning mechanisms of anthozoan-specific opsins from a reef-building coral Domestic conference

    2022.09 

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  • 視覚ロドプシンとは逆向きの異性化反応を示すハエトリグモペロプシンの光異性化機構解析 Domestic conference

    犬飼 紫乃, 片山 耕大, 杉原 智博, 小柳 光正, 寺北 明久, 神取 秀樹

    第16回分子科学討論会  2022.09 

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  • 松果体オプシン欠損個体を用いたゼブラフィッシュの光依存的行動の解析 Domestic conference

    和田清二, 小柳光正, 寺北明久

    日本動物学会第93回早稲田大会  2022.09 

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  • ハエトリグモのピンぼけ像にもとづく奥行き知覚を支えるロドプシンの吸収極大波長制御メカニズムの解析 Domestic conference

    佐藤龍, 永田崇, 寺北明久, 小柳光正

    日本動物学会第93回早稲田大会  2022.09 

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  • 造礁サンゴの花虫綱特異的オプシンが駆動するシグナル伝達特性に関する解析 Domestic conference

    岩崎誠, 酒井祐輔, 小柳光正, 寺北明久

    日本動物学会第93回早稲田大会  2022.09 

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  • 造礁サンゴで発現する花虫綱特異的オプシンにおける吸収スペクトルの制御メカニズムの解析 Domestic conference

    酒井祐輔, 小柳光正, 寺北明久

    日本動物学会第93回早稲田大会  2022.09 

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  • 非視覚オプシンの機能解明のための「発光遺伝学」的解析法の開発の試み Domestic conference

    岩崎誠, 和田清二, 永田崇, 杉原智博, 小柳光正, 寺北明久

    第22回日本光生物学協会年会  2022.08 

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  • 造礁サンゴで発現する花虫綱特異的オプシンの吸収波長特性 Domestic conference

    酒井祐輔, 小柳光正, 寺北明久

    第22回日本光生物学協会年会  2022.08 

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  • ゼブラフィッシュを用いた松果体オプシンの関わる光依存的行動の解析 Domestic conference

    和田清二, 小柳光正, 寺北明久

    第22回日本光生物学協会年会  2022.08 

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  • 平板動物のGPCRの解析によるオプシンの起源の探求 Domestic conference

    髙橋 直樹, 寺北 明久, 小柳光正

    日本進化学会第24回沼津大会  2022.08 

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  • 造礁サンゴで発現する花虫綱特異的オプシンの分子特性解析 Domestic conference

    酒井祐輔, 小柳光正, 寺北明久

    日本動物学会近畿支部研究発表会  2022.05 

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  • ゼブラフィッシュを用いた松果体光情報が伝達される脳領域の解析 Domestic conference

    和田清二, 小柳光正, 寺北明久

    日本動物学会近畿支部研究発表会  2022.05 

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  • Spectroscopic characterization of anthozoa-specific opsins found in a reef-building coral Domestic conference

    Yusuke Sakai, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第43回札幌大会  2021.12 

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  • Five opsins sensitive to blue to green lights are co-expressed in the eye photoreceptors of the terrestrial slug Limax Domestic conference

    Ryota Matsuo, Mitsumasa Koyanagi, Tomohiro Sugihara, Yuko Matsuo, Akihisa Terakita

    日本比較生理生化学会第43回札幌大会  2021.12 

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  • Transmission of light information generated in the pineal organ to the midbrain in zebrafish Domestic conference

    Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第43回札幌大会  2021.12 

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  • Molecular properties of opsin-like GPCRs identified in a primitive multicellular animal Domestic conference

    Naoki Takahashi, Akihisa Terakita, Mitsumasa Koyanagi

    日本比較生理生化学会第43回札幌大会  2021.12 

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  • Comparative investigation of G protein activation ability of a non-visual opsin, zebrafish Opn3 Domestic conference

    Taishi Shirata, Tomohiro Sugihara, Takashi Nagata, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第43回札幌大会  2021.12 

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  • A possible regulation of cone light responses by melanopsin distributed to horizontal cells in the larval zebrafish Domestic conference

    Momoka Mano, Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第43回札幌大会  2021.12 

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  • Toward detection of neural activity changes in the zebrafish brain derived from extraocular photoreceptions Domestic conference

    Yuya Namikoshi, Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第43回札幌大会  2021.12 

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  • オプシン欠損変異体を用いたゼブラフィッシュ松果体光応答の解析 Domestic conference

    和田清二, 小柳光正, 寺北明久

    日本動物学会第92回オンライン米子大会  2021.09 

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  • 造礁性のウスエダミドリイシがもつ多様なオプシン類の光受容特性の解析 Domestic conference

    酒井祐輔, 塚本寿夫, 小柳光正, 寺北明久

    日本動物学会第92回オンライン米子大会  2021.09 

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  • 深海での光受容に特化したジンベエザメの視覚 Domestic conference

    山口和晃, 小柳光正, 佐藤圭一, 寺北明久, 工樂樹洋

    日本動物学会第92回オンライン米子大会  2021.09 

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  • 原始的な多細胞動物に存在するオプシン様GPCRの解析 Domestic conference

    髙橋直樹, 寺北明久, 小柳光正

    日本動物学会第92回オンライン米子大会  2021.09 

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  • 非視覚オプシンゼブラフィッシュOpn3のGタンパク質活性化能の解析 Domestic conference

    白田泰士, 杉原智博, 永田崇, 小柳光正, 寺北明久

    日本動物学会第92回オンライン米子大会  2021.09 

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  • ゼブラフィッシュ網膜におけるメラノプシン発現水平細胞の光に対する応答の解析 Domestic conference

    真野桃歌, 和田清二, 小柳光正, 寺北明久

    日本動物学会第92回オンライン米子大会  2021.09 

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  • ハエトリグモのユニークな奥行き知覚メカニズムを支えるロドプシンの吸収極大波長制御機構の解析 Domestic conference

    佐藤龍, 永田崇, 寺北明久, 小柳光正

    日本動物学会第92回オンライン米子大会  2021.09 

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  • 哺乳類の非視覚オプシンOpn3の分子特性の解析 Domestic conference

    高草大悟, 杉原智博, 寺北明久, 小柳光正

    日本動物学会第92回オンライン米子大会  2021.09 

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  • 松果体オプシン、パラピノプシン変異ゼブラフィッシュを用いた光依存的な行動の解析 Domestic conference

    山本悠貴, 斉藤智香, 和田清二, 小柳光正, 寺北明久

    日本動物学会第92回オンライン米子大会  2021.09 

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    Presentation type:Poster presentation  

  • 有袋類の非視覚オプシンに着目した哺乳類の光受容の変遷 Domestic conference

    小柳光正, 高草大悟, 清成寛

    日本進化学会第23回東京大会  2021.08 

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  • 造礁サンゴがもつ多様なオプシン類の光受容特性の解析 Domestic conference

    酒井祐輔, 小柳光正, 寺北明久

    日本動物学会近畿支部研究発表会  2021.05 

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  • 非視覚オプシンの解析のための選択的活性化法の開発 Domestic conference

    岩崎 誠, 和田清二, 永田崇, 杉原智博, 小柳光正, 寺北明久

    日本動物学会近畿支部研究発表会  2021.05 

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  • Functional analysis of melaonpsin expressed in retinal horizontal cells of zebrafish Domestic conference

    Momoka Mano, Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    Functional analysis of melaonpsin expressed in retinal horizontal cells of zebrafish  2020.11 

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  • Toward a new method for selective activation of a non-visual opsin Domestic conference

    Makoto Iwasaki, Tomohiro Sugihara, Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    Toward a new method for selective activation of a non-visual opsin  2020.11 

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  • Investigation of opsins in the reef-building coral, Acropora tenuis, exhibiting a light-response behavior at the larval stage Domestic conference

    Investigation of opsins in the reef-building coral, Acropora tenuis, exhibiting a light-response behavior at the larval stage  2020.11 

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  • Investigation of opsin-like GPCRs identified in a primitive multicellular animal Domestic conference

    Investigation of opsin-like GPCRs identified in a primitive multicellular animal  2020.11 

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  • Histological investigation of deep brain photoreceptors in the larval and adult lampreys Domestic conference

    Histological investigation of deep brain photoreceptors in the larval and adult lampreys  2020.11 

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  • Comparative investigation of G protein activation ability of members of a non-visual opsin, Opsin3 group. Domestic conference

    Taishi Shirata, Tomohiro Sugihara, Mitsumasa Koyanagi, Akihisa Terakita

    2020.11 

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  • 奥行き知覚を支えるハエトリグモのロドプシンの分子進化 Domestic conference

    小柳光正, 永田崇, 寺北明久

    日本進化学会第22回大会  2020.09 

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  • 造礁サンゴAcropora tenuisの幼生における光応答的な遊泳行動と成体の分布パターンへの影響 Domestic conference

    酒井祐輔, 加藤輝, 小山宏史, Alyson Kuba, 高橋弘樹, 藤森俊彦, 服田昌之, Andrew Negri, Andrew Baird, 上野直人

    日本進化学会第22回大会  2020.09 

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  • ゼブラフィッシュにおける松果体光応答:「色検出」とその脳投射 Invited Domestic conference

    和田清二, 沈宝國, 山下(川野) 絵美, 永田崇, 日比正彦, 保智己, 小柳光正, 寺北明久

    日本動物学会第91回大会  2020.09 

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  • 奥行き知覚を支えるハエトリグモ視物質の特徴的な吸収スペクトルの獲得 Domestic conference

    小柳光正, 永田崇, 寺北明久

    日本動物学会第91回大会  2020.09 

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  • ゼブラフィッシュ網膜におけるメラノプシンの視覚への関与に関する解析 Domestic conference

    真野桃歌, 和田清二, 小柳光正, 寺北明久

    日本動物学会第91回大会  2020.09 

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  • ゼブラフィッシュ松果体の色検出を担う光受容タンパク質の不活性化機構の解析 Domestic conference

    沈宝国, 和田清二, 西岡春香, 杉原智博, 永田崇, 橘木修志, 山下(川野)絵美, 小柳光正, 寺北明久

    日本動物学会第91回大会  2020.09 

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  • ゼブラフィッシュにおける松果体光情報の処理に関わる脳部位候補の解析 Domestic conference

    和田清二, 小柳光正, 寺北明久

    日本動物学会第91回大会  2020.09 

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  • ゼブラフィッシュの幼魚の明暗環境に関する嗜好性の決定における松果体opsinであるparapinopsinを基盤とした比色機序の寄与についての評価(Evaluating contribution of pineal opsin, parapinopsin-based color opponency to preference for dark and light in zebrafish larvae) Domestic conference

    Saito Tomoka, Wada Seiji, Shen Baoguo, Nakata Genki, Koyanagi Mitsumasa, Terakita Akihisa

    比較生理生化学  2020.04  日本比較生理生化学会

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  • 動物の視覚光センサータンパク質・ロドプシンにおける発色団のプロトン化に関する変異体解析 Domestic conference

    永田 崇,小柳 光正,塚本 寿夫,Eshita Mutt,Gebhard F. X. Schertler,Xavier Deupi,寺北明久

    物性研短期研究会「理論タンパク質物性科学の最前線:理論と実験との密な協働」  2020.02 

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    Presentation type:Poster presentation  

    Venue:柏・東京大学物性研究所  

  • Jumping spider Rh-1 as a possible model of bistable rhodopsins for structural, functional and optogenetic studies Domestic conference

    Akihisa Terakita, Mitsumasa Koyanagi, Tomohiro Sugihara, Takashi Nagata

    CREST「光の特性を活用した生命機能の時空間制御技術の開発と応用」第4回領域会議  2020.01 

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    Presentation type:Poster presentation  

    Venue:東京・東京大学  

  • 動物の双安定型ロドプシンを用いたGPCRシグナル伝達の光操作 Invited Domestic conference

    小柳 光正

    Promega Dynamic Connection 2019  2019.12 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:福岡・ハーバービレッジ  

  • Evaluating contribution of pineal opsin, parapinopsin-based color opponency to preference for dark and light in zebrafish larvae Domestic conference

    Tomoka Saito, Seiji Wada, Baoguo Shen, Genki Nakata , Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第41回東京大会  2019.11 

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    Venue:東京・東京大学  

  • Optical regulation of intracellular signaling using bistable animal opsins Domestic conference

    Mitsumasa Koyanagi, Seiji Wada, Baoguo Shen, Takashi Nagata, Akihisa Terakita

    日本比較生理生化学会第41回東京大会  2019.11 

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    Venue:東京・東京大学  

  • A signaling pathway of “color information” generated in parapinopsin-expressing pineal photoreceptor cells to brain neurons in zebrafish Domestic conference

    Seiji Wada, Baoguo Shen, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第41回東京大会  2019.11 

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    Venue:東京・東京大学  

  • サメを知らずに脊椎動物を語れるかーゲノムから視覚を探る Invited Domestic conference

    工樂 樹洋,山口 和晃,小柳 光正,寺北 明久

    基礎生物学研究所セミナー「異分野融合による次世代光生物学研究会」  2019.11 

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    Presentation type:Oral presentation (invited, special)  

    Venue:岡崎・岡崎コンファレンスセンター  

  • 板鰓類のゲノム解析:「サメらしさ」に分子から迫る Domestic conference

    工樂 樹洋,原 雄一郎,山口 和晃,野津 了,小柳 光正,寺北 明久,喜屋 武樹,西田 清徳,兵藤 晋,佐藤 圭一

    基礎生物学研究所セミナー「異分野融合による次世代光生物学研究会」  2019.11 

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    Presentation type:Poster presentation  

    Venue:岡崎・岡崎コンファレンスセンター  

  • 動物のオプシンの起源の探索 Domestic conference

    小柳 光正,高橋 直樹,寺北 明久

    基礎生物学研究所セミナー「異分野融合による次世代光生物学研究会」  2019.11 

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    Venue:岡崎・岡崎コンファレンスセンター  

  • 松果体におけるオプシンの分子特性と波長識別 Invited Domestic conference

    和田 清二,沈 宝國,山下(川野) 絵美,永田 崇,日比 正彦,保 智己,小柳 光正,寺北 明久

    基礎生物学研究所セミナー「異分野融合による次世代光生物学研究会」  2019.11 

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    Presentation type:Oral presentation (invited, special)  

    Venue:岡崎・岡崎コンファレンスセンター  

  • 動物の光受容タンパク質の解析から生態・進化を探る Invited Domestic conference

    小柳 光正

    第四回軟骨魚類研究会  2019.10 

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    Presentation type:Oral presentation (invited, special)  

    Venue:沖縄・琉球大学熱帯生物圏研究センター瀬底研究施設  

  • Light regulation of cell responses by animal rhodopsins Invited International conference

    Mitsumasa Koyanagi

    9th Asia and Oceania Conference on Photobiology   2019.09 

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    Presentation type:Oral presentation (invited, special)  

    Venue:Crowne Plaza Qingdao Ocean Spring Resort, Qingdao, China  

  • 動物の双安定型ロドプシンを用いた細胞内シグナル伝達の光操作 Invited Domestic conference

    小柳 光正

    日本動物学会第90回大会  2019.09 

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    Venue:大阪・大阪市立大学全学共通教育棟  

  • ハエトリグモの視物質の吸収スペクトルと奥行き知覚メカニズムの進化との関係 Domestic conference

    小柳 光正,永田 崇,斉藤 智香,寺北 明久

    日本動物学会第90回大会  2019.09 

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    Presentation type:Oral presentation (general)  

    Venue:大阪・大阪市立大学全学共通教育棟  

  • ゼブラフィッシュ松果体における色情報検出を担う光受容体 Invited Domestic conference

    和田 清二,沈 宝國,山下(川野) 絵美,永田 崇,日比 正彦,保 智己,小柳 光正,寺北 明久

    日本動物学会第90回大会  2019.09 

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    Presentation type:Oral presentation (invited, special)  

    Venue:大阪・大阪市立大学全学共通教育棟  

  • ゼブラフィッシュ松果体における非感色性光応答を担う光受容タンパク質の解析 Domestic conference

    和田 清二,沈 宝國,山下(川野) 絵美,永田 崇,日比 正彦,保 智己,小柳 光正,寺北 明久

    日本動物学会第90回大会  2019.09 

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    Venue:大阪・大阪市立大学全学共通教育棟  

  • ゼブラフィッシュにおいて松果体光受容タンパク質が関わる光点灯時の遊泳活性の制御 Domestic conference

    中田 玄樹,和田 清二,小柳 光正,寺北 明久

    日本動物学会第90回大会  2019.09 

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    Venue:大阪・大阪市立大学全学共通教育棟  

  • ゼブラフィッシュ松果体における波長検出に関わる光受容タンパク質パラピノプシンの不活性化機構の解析 Domestic conference

    沈 宝国,和田 清二,永田 崇,山下(川野) 絵美,小柳 光正,寺北 明久

    日本動物学会第90回大会  2019.09 

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    Venue:大阪・大阪市立大学全学共通教育棟  

  • サメのゲノム配列から明らかとなった生息水深への視覚の適応 Domestic conference

    山口 和晃,小柳 光正,原 雄一郎,野津 了,佐藤 圭一,寺北 明久,工樂 樹洋

    日本動物学会第90回大会  2019.09 

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    Venue:大阪・大阪市立大学全学共通教育棟  

  • 無顎類ヤツメウナギの脳深部に存在する新規光受容器官の非視覚オプシンに着目した組織学的解析 Domestic conference

    山下(川野) 絵美,由良 南々帆,小柳 光正,和田 清二,寺北 明久,保 智己

    日本動物学会第90回大会  2019.09 

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    Presentation type:Oral presentation (general)  

    Venue:大阪・大阪市立大学全学共通教育棟  

  • 無脊椎動物視覚ロドプシンにおける対イオン−プロトン化シッフ塩基間相互作用の変異体解析 Domestic conference

    永田 崇,小柳 光正,塚本 寿夫,Eshita Mutt,Gebhard F. X. Schertler,Xavier Deupi,寺北 明久

    ISSPワークショップ「レチナールタンパク質の光機能発現の物理と化学」  2019.09 

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    Venue:柏・東京大学物性研究所  

  • Color dependent light regulation of cell responses by a non-visual bistable opsin parapinopsin International conference

    Mitsumasa Koyanagi, Seiji Wada, Baoguo Shen, Takashi Nagata, Akihisa Terakita

    2019 ESP-IUPB World Congress  2019.08 

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    Venue:Crowne Plaza Barcelona Fira Center, Barcelona, Spain  

  • オプシンファミリーに近縁なGPCRに着目したオプシンの起源の探索 Domestic conference

    小柳 光正,高橋 直樹,寺北 明久

    日本進化学会第21回大会  2019.08 

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    Venue:札幌・北海道大学  

  • Spectral tuning in butterfly long wavelength-sensitive visual opsins International conference

    Tomoka Saito, Mitsumasa Koyanagi, Tomohiro Sugihara, Takashi Nagata, Kentaro Arikawa, Akihisa Terakita

    FASEB SRC The Biology & Chemistry of Vision  2019.06 

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    Presentation type:Poster presentation  

    Venue:Steamboat springs, Colorado, U.S.A.  

  • Chromatic response with a single kind of opsin in the zebrafish pineal organ International conference

    Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    FASEB SRC The Biology & Chemistry of Vision  2019.06 

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    Venue:Steamboat springs, Colorado, U.S.A.  

  • 動物の光受容の分子基盤の多様性と進化 Invited Domestic conference

    小柳 光正

    総合研究大学院大学先導科学研究科公開セミナー  2019.05 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:葉山・総合研究大学院大学先導科学研究科  

  • ゼブラフィッシュ松果体に発現する非視覚光受容タンパク質による行動の制御 Domestic conference

    中田 玄樹,藤井 耀,和田 清二,小柳 光正,寺北 明久

    2019年度動物学会近畿支部研究発表会  2019.05 

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    Venue:兵庫・甲南大学フロンティアサイエンス学部  

  • 板鰓類3種のゲノム解析:「サメらしさ」に分子から迫る Domestic conference

    原 雄一郎,山口 和晃,野津 了,小柳 光正,喜屋武 樹,寺北 明久、西田 清徳,兵藤 晋,佐藤 圭一,工樂 樹洋

    平成31年度日本水産学会春季大会  2019.03 

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    Venue:東京・東京海洋大学  

  • Detection of “color changes” with a single kind of opsin in the zebrafish pineal organ International conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Masahiro Hibi, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    10th OCARINA International Symposium  2019.03 

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    Venue:大阪・大阪市立大学学術情報センター  

  • Contribution of parapinopsin molecular property to cellular light responses in the zebrafish pineal organ International conference

    Baoguo Shen, Seiji Wada, Emi Kawano-Yamashita, Mitsumasa Koyanagi, Akihisa Terakita

    10th OCARINA International Symposium  2019.03 

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    Venue:大阪・大阪市立大学学術情報センター  

  • Animal opsins: non-visual functions and optogenetic applications International conference

    Akihisa Terakita, Mitsumasa Koyanagi

    10th OCARINA International Symposium  2019.03 

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    Venue:大阪・大阪市立大学学術情報センター  

  • Behavioral investigation of non-visual photoreception with pineal-specific opsin- knockout zebrafish International conference

    Genki Nakata, Seiji Wada, Mitsumasa Koyanagi and Akihisa Terakita

    10th OCARINA International Symposium  2019.03 

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    Venue:大阪・大阪市立大学学術情報センター  

  • Evaluation of the pineal wavelength discrimination based on a pineal-specific opsin parapinopsin in the zebrafish behaviours International conference

    Tomoka Saito, Seiji wada, Baoguo Shen, Takashi Nagata, Mitsumasa Koyanagi and Akihisa Terakita

    10th OCARINA International Symposium  2019.03 

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    Venue:大阪・大阪市立大学学術情報センター  

  • A nobel type of opsin with optogenetic potential: animal opsin-based photopigment as a potential dark-active and light-Inactivated G protein-coupled receptor International conference

    Takashi Nagata, Mitsumasa Koyanagi, Robert Lucas, Akihisa Terakita

    10th OCARINA International Symposium  2019.03 

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    Venue:大阪・大阪市立大学学術情報センター  

  • ゼブラフィッシュ松果体の単一オプシンによる色情報検出 Invited Domestic conference

    和田 清二,沈 宝國,山下(川野)絵美,永田 崇, 日比 正彦, 保 智己, 小柳 光正,寺北 明久

    第13回バイオイメージングフォーラム&基礎生物学研究所重点共同利用 合同シンポジウム  2019.02 

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    Venue:岡崎・岡崎コンファレンスセンター  

  • Optical regulation of GPCR signalings using bistable animal opsins Invited International conference

    Mitsumasa Koyanagi

    1st International Symposium on Interdisciplinary Approaches to Integrative Understanding of Biological Signaling Networks  2019.02 

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  • 板鰓類の視覚を司る遺伝子と生息環境の関係を探る Domestic conference

    山口 和晃,小柳 光正,原 雄一郎,寺北 明久,工樂 樹洋

    板鰓類シンポジウム2018  2018.12 

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    Venue:長崎・長崎大学文教スカイホール  

  • Relationship between absorption spectra of spider rhodopsins and evolution of depth perception mechanism Domestic conference

    Mitsumasa Koyanagi, Takashi Nagata, Tomoka Saito, Yu Maekawa, Gen Suwa, Akihisa Terakita

    日本比較生理生化学会第40回大会  2018.11 

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    Venue:神戸・神戸大学先端融合研究環統合研究拠点コンベンションホール  

  • Opsins involved in the visual function of the terrestrial slug Limax Domestic conference

    Ryota Matsuo, Mitsumasa Koyanagi, Tomohiro Sugihara, Akihisa Terakita, Haruka Hishiyama, Yuko Matsuo

    日本比較生理生化学会第40回大会  2018.11 

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    Presentation type:Poster presentation  

    Venue:神戸・神戸大学先端融合研究環統合研究拠点コンベンションホール  

  • Histochemical investigation of non-visual opsin-expressing photoreceptor cells in the larval and adult lamprey brains Domestic conference

    Emi Kawano-Yamashita, Satoshi Tamotsu, Mitsumasa Koyanagi, Seiji Wada, Akihisa Terakita

    日本比較生理生化学会第40回大会  2018.11 

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    Presentation type:Poster presentation  

    Venue:神戸・神戸大学先端融合研究環統合研究拠点コンベンションホール  

  • Relationship between pineal wavelength discrimination involving parapinopsin and natural light conditions in the zebrafish Domestic conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Masahiko Hibi, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第40回大会  2018.11 

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    Presentation type:Poster presentation  

    Venue:神戸・神戸大学先端融合研究環統合研究拠点コンベンションホール  

  • Comparative investigation of light responses of pineal photoreceptor cells containing different types of opsins with transgenic zebrafish Domestic conference

    Baoguo Shen, Seiji Wada, Emi Kawano-Yamashita, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第40回大会  2018.11 

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    Venue:神戸・神戸大学先端融合研究環統合研究拠点コンベンションホール  

  • Histochemical investigation of phototransduction-related gene expression in zebrafish pineal photoreceptor cells Domestic conference

    Haruka Nishioka, Takashi Nagata, Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第40回大会  2018.11 

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    Presentation type:Poster presentation  

    Venue:神戸・神戸大学先端融合研究環統合研究拠点コンベンションホール  

  • Contribution of a pineal opsin to light-suppressed melatonin secretion and light-regulated locomotor activity in zebrafish pineal organ Domestic conference

    Genki Nakata, Seiji Wada, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第40回大会  2018.11 

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    Presentation type:Poster presentation  

    Venue:神戸・神戸大学先端融合研究環統合研究拠点コンベンションホール  

  • Functionality of bistable animal opsins for optogenetic regulation of cellular signal transductions Invited International conference

    Mitsumasa Koyanagi

    18th International Conference on Retinal Proteins  2018.09 

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    Presentation type:Oral presentation (invited, special)  

    Venue:Hockley Valley Resort, Ontario, Canada  

  • Peropsin as a potential light-inactivated G protein-coupled receptor International conference

    Takashi Nagata, Mitsumasa Koyanagi, Robert Lucas, Akihisa Terakita

    18th International Conference on Retinal Proteins  2018.09 

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    Presentation type:Poster presentation  

    Venue:Hockley Valley Resort, Ontario, Canada  

  • Color opponency with a bistable pigment parapinopsin in the zebrafish pineal organ International conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Masahiko Hibi, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    18th International Conference on Retinal Proteins  2018.09 

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    Presentation type:Poster presentation  

    Venue:Hockley Valley Resort, Ontario, Canada  

  • Dark-active and light-inactivated G protein-coupled receptors based on an animal opsin, peropsin Invited Domestic conference

    Takashi Nagata, Mitsumasa Koyanagi,Robert Lucas and Akihisa Terakita

    日本生物物理学会第56回年会  2018.09 

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    Presentation type:Oral presentation (invited, special)  

    Venue:岡山・岡山大学津島キャンパス  

  • クモの視物質の吸収スペクトルと奥行き知覚メカニズムの進化との関係 Domestic conference

    小柳 光正,永田 崇,斉藤 智香,前川 優,諏訪 元,寺北 明久

    日本動物学会第89回大会  2018.09 

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    Presentation type:Poster presentation  

    Venue:札幌・札幌コンベンションセンター  

  • 松果体におけるパラピノプシンの寄与する光応答と自然光との関わり Domestic conference

    和田 清二,沈 宝國,山下(川野)絵美,永田 崇, 日比 正彦, 保 智己, 小柳 光正,寺北 明久

    日本動物学会第89回大会  2018.09 

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    Presentation type:Poster presentation  

    Venue:札幌・札幌コンベンションセンター  

  • 幼生期及び成体期のヤツメウナギにおける非視覚オプシンが発現する脳深部光受容器官の組織学的解析 Domestic conference

    山下(川野)絵美,保 智己,小柳 光正,和田 清二,寺北 明久

    日本動物学会第89回大会  2018.09 

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    Presentation type:Poster presentation  

    Venue:札幌・札幌コンベンションセンター  

  • 光で不活性化される Gタンパク質共役受容体としての特徴を持つペロプシン Invited Domestic conference

    永田 崇,小柳 光正,Robert Lucas,寺北 明久

    日本動物学会第89回大会  2018.09 

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    Presentation type:Poster presentation  

    Venue:札幌・札幌コンベンションセンター  

  • 遺伝子導入ゼブラフィッシュを用いたオプシンの分子特性が寄与する松果体の光応答の解析 Domestic conference

    沈 宝國,和田 清二,山下(川野)絵美,小柳 光正,寺北 明久

    日本動物学会第89回大会  2018.09 

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    Presentation type:Poster presentation  

    Venue:札幌・札幌コンベンションセンター  

  • ゼブラフィッシュ松果体における波長識別を担う光受容体 Invited Domestic conference

    和田 清二,沈 宝國,山下(川野)絵美,永田 崇, 日比 正彦, 保 智己, 小柳 光正,寺北 明久

    日本動物学会第89回大会  2018.09 

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    Presentation type:Oral presentation (invited, special)  

    Venue:札幌・札幌コンベンションセンター  

  • ナメクジの視覚機能に関わるオプシンの解析 Domestic conference

    松尾 亮太,小柳 光正,杉原 智博,寺北 明久,西山 春佳,松尾 優子

    日本動物学会第89回大会  2018.09 

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    Presentation type:Poster presentation  

    Venue:札幌・札幌コンベンションセンター  

  • チョウの生殖行動を制御する光受容体 Domestic conference

    塚本 寿夫,内山 博允,秋山 時穂,小柳 光正,古谷 祐詞,寺北 明久,蟻川 謙太郎

    日本動物学会第89回大会  2018.09 

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    Presentation type:Poster presentation  

    Venue:札幌・札幌コンベンションセンター  

  • Analyses of pineal photoresponses using opsin-deficient and -replaced zebrafish mutants Domestic conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Masahiko Hibi, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    第24回小型魚類研究会  2018.08 

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    Presentation type:Poster presentation  

    Venue:名古屋・名古屋大学野依記念学術交流館  

  • サメのオプシン遺伝子レパートリーと生息環境との関係を探る Domestic conference

    山口 和晃,小柳 光正,原 雄一郎,寺北 明久,工樂 樹洋

    日本進化学会第20回大会  2018.08 

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    Presentation type:Oral presentation (general)  

    Venue:東京・東京大学駒場Iキャンパス  

  • クモのロドプシンの分子進化と奥行き知覚メカニズムの関係 Domestic conference

    小柳 光正,永田 崇,斉藤 智香,寺北 明久

    日本進化学会第20回大会  2018.08 

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    Presentation type:Poster presentation  

    Venue:東京・東京大学駒場Iキャンパス  

  • 全トランスレチナール結合オプシン・ペロプシンの光不活性化型GPCRとしての性質 Domestic conference

    永田 崇,小柳 光正,Robert Lucas,寺北 明久

    第20回日本光生物学協会年会  2018.08 

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    Presentation type:Oral presentation (general)  

    Venue:京都・京都大学北部構内理学研究科セミナーハウス  

  • ゼブラフィッシュ松果体における1種類のオプシンに基づく波長検出応答 Domestic conference

    和田 清二,沈 宝國,山下(川野)絵美,永田 崇, 日比 正彦, 保 智己, 小柳 光正,寺北 明久

    第20回日本光生物学協会年会  2018.08 

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    Presentation type:Oral presentation (general)  

    Venue:京都・京都大学北部構内理学研究科セミナーハウス  

  • 動物の光受容タンパク質の多様性とその活用術 Invited Domestic conference

    小柳 光正

    大阪大学生命機能研究科研究交流会(FBSコロキウム)189   2018.06 

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    Presentation type:Oral presentation (invited, special)  

    Venue:大阪・大阪大学吹田キャンパス  

  • 不可視光線環境下におけるゼブラフィッシュのparapinopsinが関与する松果体光感応の解析(Investigation of the pineal photoresponse involving parapinopsin in the zebrafish under blight light conditions) Domestic conference

    Wada Seiji, Shen Baoguo, Kawano-Yamashita Emi, Nagata Takashi, Tamotsu Satoshi, Koyanagi Mitsumasa, Terakita Akihisa

    比較生理生化学  2018.04  日本比較生理生化学会

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    Presentation type:Oral presentation (general)  

  • Color opponency with a single kinds of bistable opsin in the zebrafish pineal organ International conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Masahiro Hibi, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    9th OCARINA International Symposium  2018.03 

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    Presentation type:Poster presentation  

    Venue:大阪・大阪市立大学学術情報センター  

  • Characterization of arrestin binding to parapinopsin, a photopigment involved in pineal wavelength discrimination International conference

    Takashi Nagata, Mitsumasa Koyanagi, Emi Kawano-Yamashita, Seiji Wada, Akihisa Terakita

    9th OCARINA International Symposium  2018.03 

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    Presentation type:Poster presentation  

    Venue:大阪・大阪市立大学学術情報センター  

  • Investigation of amino acid residues involved in spectral tuning of butterfly long-wavelength-sensitive opsins International conference

    Tomoka Saito, Mitsumasa Koyanagi, Tomohiro Sugihara, Kentaro Arikawa, Akihisa Terakita

    9th OCARINA International Symposium  2018.03 

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    Presentation type:Poster presentation  

    Venue:大阪・大阪市立大学学術情報センター  

  • Contribution of parapinopsin “bistability” to light-responses in the zebrafish pineal organs International conference

    Baoguo Shen, Seiji Wada, Emi Kawano-Yamashita, Mitsumasa Koyanagi, Akihisa Terakita

    9th OCARINA International Symposium  2018.03 

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    Presentation type:Poster presentation  

    Venue:大阪・大阪市立大学学術情報センター  

  • Estimating spectral sensitivities of various opsins based on biochemical responses of cultured cells expressing opsins International conference

    Tomohiro Sugihara, Takashi Nagata, Benjamin Mason, Mitsumasa Koyanagi, Akihisa Terakita

    9th OCARINA International Symposium  2018.03 

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    Presentation type:Poster presentation  

    Venue:大阪・大阪市立大学学術情報センター  

  • 動物の非視覚光受容タンパク質の多様性と光操作への応用 Invited Domestic conference

    小柳 光正

    日本比較生理生化学会第39回大会  2017.11 

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    Presentation type:Oral presentation (invited, special)  

    Venue:福岡・福岡大学  

  • Characterization of an opsin, peropsin, distributing to the spider brain and eyes Domestic conference

    Takashi Nagata, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第39回大会  2017.11 

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    Presentation type:Poster presentation  

    Venue:福岡・福岡大学  

  • Investigation of amino acid residues involved in spectral tuning of butterfly long-wavelength-sensitive opsins Domestic conference

    Tomoka Saito, Mitsumasa Koyanagi, Tomohiro Sugihara, Kentaro Arikawa, Akihisa Terakita

    日本比較生理生化学会第39回大会  2017.11 

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    Presentation type:Poster presentation  

    Venue:福岡・福岡大学  

  • Investigation of the pineal photoresponse involving parapinopsin in the zebrafish under blight light conditions Domestic conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    日本比較生理生化学会第39回大会  2017.11 

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    Venue:福岡・福岡大学  

  • Detergent-free approach to spectral tuning mechanisms of long-wavelength-sensitive opsins in butterfly International conference

    Tomoka Saito, Mitsumasa Koyanagi, Tomohiro Sugihara, Kentaro Arikawa, Akihisa Terakita

    The 8th Asia & Oceania Conference on Photobiology  2017.11 

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    Presentation type:Poster presentation  

    Venue:Seoul, Korea  

  • Diversity of animal rhodopsins and their potentials for optical regulation of cell signaling Domestic conference

    Mitsumasa Koyanagi, Baoguo Shen, Takashi Nagata, Lanfang Sun, Seiji Wada, Satomi Kamimura, Eriko Kage-Nakadai, Akihisa Terakita

    第9回光操作研究会  2017.10 

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    Venue:仙台・東北大学  

  • ゼブラフィッシュ松果体の光応答におけるパラピノプシンの分子特性“双安定性”の寄与についての解析 Domestic conference

    沈 宝國, 和田 清二, 山下(川野)絵美, 小柳 光正, 寺北 明久

    日本動物学会第88回大会  2017.09 

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    Presentation type:Oral presentation (general)  

    Venue:富山・富山県民会館  

  • ゼブラフィッシュ松果体におけるメラトニン分泌の光制御に関わるオプシンの解析 Domestic conference

    寺北 明久, 和田 清二, 藤井 耀, 小柳 光正

    日本動物学会第88回大会  2017.09 

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    Presentation type:Oral presentation (general)  

    Venue:富山・富山県民会館  

  • ゼブラフィッシュ松果体の波長識別応答における光受容タンパク質パラピノプシンの分子特性の重要性 Domestic conference

    和田 清二, 沈 宝國, 山下(川野)絵美, 永田 崇, 保 智己, 小柳 光正, 寺北 明久

    日本動物学会第88回大会  2017.09 

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    Presentation type:Oral presentation (general)  

    Venue:富山・富山県民会館  

  • 松果体波長識別応答に関わる光受容タンパク質パラピノプシンのアレスチン結合に関する解析 Domestic conference

    永田 崇, 小柳 光正, 山下(川野)絵美, 和田 清二, 小澤 岳昌, 寺北 明久

    日本動物学会第88回大会  2017.09 

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    Presentation type:Oral presentation (general)  

    Venue:富山・富山県民会館  

  • パラピノプシンの双安定性に着目した細胞応答の波長依存的な光制御 Domestic conference

    小柳 光正, 沈 宝國, 永田 崇, 孫 蘭芳, 和田 清二, 上村 了美, 中台(鹿毛)枝里子, 寺北 明久

    日本動物学会第88回大会  2017.09 

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    Presentation type:Oral presentation (general)  

    Venue:富山・富山県民会館  

  • Contribution of a molecular property of a pineal opsin parapinopsin to cellular responses Domestic conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    第55回生物物理学会年会  2017.09  (一社)日本生物物理学会

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    Venue:熊本・熊本大学黒髪北地区  

  • 有袋類に着目した哺乳類の進化過程で失われた非視覚系光受容タンパク質の機能解析 Domestic conference

    小柳 光正, 冨田 和志, 清成 寛, 寺北 明久

    日本進化学会第19回大会  2017.08 

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    Presentation type:Poster presentation  

    Venue:京都・京都大学吉田キャンパス  

  • 松果体オプシンパラピノプシンの分子特性の細胞応答への寄与(Contribution of a molecular property of a pineal opsin parapinopsin to cellular responses) Domestic conference

    Wada Seiji, Shen Baoguo, Kawano-Yamashita Emi, Nagata Takashi, Tamotsu Satoshi, Koyanagi Mitsumasa, Terakita Akihisa

    生物物理  2017.08  (一社)日本生物物理学会

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  • Molecular properties of animal non-visual opsins and their optogenetic potentials International conference

    Baoguo Shen, Takashi Nagata, Seiji Wada, Satomi Kamimura, Eriko Kage-Nakadai, Robert J. Lucas, Gebhard F. X. Schertler, Mitsumasa Koyanagi, Akihisa Terakita

    17th HFSP Awardees Meeting  2017.07 

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    Presentation type:Poster presentation  

    Venue:Lisbon, Portugal  

  • Optical regulation of cell signaling using bistable animal opsins International conference

    Mitsumasa Koyanagi, Baoguo Shen, Takashi Nagata, Lanfang Sun, Seiji Wada, Satomi Kamimura, Eriko Kage-Nakadai, Akihisa Terakita

    2017 FASEB SUMMER RESEARCH CONFERENCES  2017.06 

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    Presentation type:Poster presentation  

    Venue:Steamboat springs, Colorado, U.S.A.  

  • ナメクジの網膜におけるβアレスチンの発現と光依存的な細胞内局在変化 Domestic conference

    松尾 亮太, 鷹取 由佳, 濱田 俊, 小柳 光正, 松尾 優子

    日本動物学会九州支部・九州沖縄植物学会・日本生態学会九州地区 2017三学会合同大分大会  2017.05 

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    Venue:大分・大分大学  

  • Functional properties of diverse animal rhodopsins and their potentials for optical regulation of cell signaling Invited International conference

    Mitsumasa Koyanagi

    International Symposium on Biophysics of Rhodopsins  2017.05 

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  • Mutational analysis of the Schiff base counterion in Jumping spider rhodopsin, an invertebrate Gq-coupled rhodopsin International conference

    Takashi Nagata, Mitsumasa Koyanagi, Hisao Tsukamoto, Eshita Mutt, Xavier Deupi, Gebhard Schertler, Akihisa Terakita

    International Symposium on Biophysics of Rhodopsins  2017.05 

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    Presentation type:Poster presentation  

    Venue:Science Seminar House in Kyoto University, Kyoto Japan  

  • Investigation of wavelength discrimination involving bistable parapinopsin in the zebrafish pineal organ International conference

    Seiji Wada, Baoguo Shen, Emi Kawano-Yamashita, Takashi Nagata, Satoshi Tamotsu, Mitsumasa Koyanagi, Akihisa Terakita

    International Symposium on Biophysics of Rhodopsins  2017.05 

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    Presentation type:Poster presentation  

    Venue:Science Seminar House in Kyoto University, Kyoto Japan  

  • Amino acid residues involved in Spectral tuning that accounts for difference in absorption maxima between two kinds of butterfly long-wavelength-sensitive opsins International conference

    Tomoka Saito, Mitsumasa Koyanagi, Tomohiro Sugihara, Kentaro Arikawa, Akihisa Terakita

    International Symposium on Biophysics of Rhodopsins  2017.05 

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    Presentation type:Poster presentation  

    Venue:Science Seminar House in Kyoto University, Kyoto Japan  

  • 光遺伝学で活躍するタンパク質分子の生物物理学研究の展望 GPCR情報伝達調節のための双安定性動物のオプシンを基盤とした色素の光遺伝学的な可能性(Perspective in Biophysical studies on protein molecules applicable for optogenetics Optogenetic potentials of bistable animal opsin-based pigments for regulating GPCR signalings) Domestic conference

    Koyanagi Mitsumasa

    生物物理  2016.10  (一社)日本生物物理学会

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  • アレスチンと双安定性のオプシンとの光依存的な結合と解離(Light-dependent association and dissociation of arrestin with bistable opsins) Domestic conference

    Nagata Takashi, Koyanagi Mitsumasa, Yamashita-Kawano Emi, Lucas Robert, Terakita Akihisa

    生物物理  2016.10  (一社)日本生物物理学会

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  • Potential of bistable pigments for optical control of cell signaling Invited International conference

    KOYANAGI Mitsumasa

    22nd International Congress of Zoology & 87th meeting of Zoological Society of Japan  2016 

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    Venue:Okinawa, Japan  

  • Optogenetic potentials of bistable animal opsin-based pigments for regulating GPCR signalings Invited Domestic conference

    KOYANAGI Mitsumasa

    Optogenetic potentials of bistable animal opsin-based pigments for regulating GPCR signalings  2016 

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  • Optical control of cell signaling using bistable animal opsin-based pigments Invited International conference

    KOYANAGI Mitsumasa

    17th International Conference on Retinal Proteins  2016 

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    Venue:Potsdam, Germany  

  • 受容タンパク質の意外な使い方~ピンぼけ像を使った奥行き知覚~ Invited Domestic conference

    小柳 光正

    49回光学五学会関西支部連合講演会  2015 

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  • Introduction of animal rhodopsins and their optogenetic potentials Invited Domestic conference

    KOYANAGI Mitsumasa

    Introduction of animal rhodopsins and their optogenetic potentials  2015 

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  • 培養細胞内2次メッセンジャーの発光モニタリングを利用した多様なオプシン類の分子特性解析の試み(Analysis of molecular properties of various opsins by bioluminescence monitoring of second-messengers in cultured cells) Domestic conference

    Nagata Takashi, Sugihara Tomohiro, Koyanagi Mitsumasa, Terakita Akihisa

    生物物理  2014.08  (一社)日本生物物理学会

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  • Wavelength sensitivity and depth perception mechanism in a jumping spider Invited International conference

    KOYANAGI Mitsumasa

    International Society for Behavioral Ecology Conference (ISBE2014)  2014 

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    Venue:New York, USA  

  • Molecular properties of diverse and engineered bistable pigments and their optogenetic potential Invited International conference

    KOYANAGI Mitsumasa

    17th International Conference on Retinal Proteins  2014 

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    Venue:Nagahama, Japan  

  • Diversity and evolution of arthropod vision revealed by the molecular basis of jumping spider vision Invited Domestic conference

    KOYANAGI Mitsumasa

    Diversity and evolution of arthropod vision revealed by the molecular basis of jumping spider vision  2014 

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    Presentation type:Oral presentation (invited, special)  

  • 双安定性のロドプシン類の分子特性とそれらの光遺伝学への応用の可能性(Molecular properties of animal bistable rhodopsins and their optogenetic potential) Domestic conference

    Sugihara Tomohiro, Koyanagi Mitsumasa, Terakita Akihisa

    生物物理  2013.09  (一社)日本生物物理学会

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    Presentation type:Oral presentation (general)  

  • 分子進化学的・分子生理学的アプローチによる動物の光受容の分子基盤の研究 Invited Domestic conference

    小柳 光正

    日本動物学会第84回大会  2013 

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    Presentation type:Oral presentation (invited, special)  

  • 光受容タンパク質の性質と視覚機能の意外な関係~ハエトリグモのピンぼけ像に基づく奥行き知覚~ Invited Domestic conference

    小柳 光正

    9回北大若手研究者交流会  2013 

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    Presentation type:Oral presentation (invited, special)  

  • Functional diversity of pineal photopigment parapinopsin Invited International conference

    KOYANAGI Mitsumasa

    6th Asia and Oceania Conference on Photobiology (AOCP)  2013 

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    Presentation type:Oral presentation (invited, special)  

    Venue:Sydney, Australia  

  • 受容タンパク質に着目した動物の光受容系の進化と多様性の研究 -ハエトリグモのピンぼけ像に基づく新規奥行き知覚メカニズム- Invited Domestic conference

    小柳 光正

    17回日本光生物学協会年会  2012 

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    Presentation type:Oral presentation (invited, special)  

  • 光受容タンパク質の分子進化と生理機能との連関 Invited Domestic conference

    小柳 光正

    日本進化学会第14回大会  2012 

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    Presentation type:Oral presentation (invited, special)  

  • Diversity and evolution of opsin-based pigments in non-visual function Invited International conference

    KOYANAGI Mitsumasa

    8th International Congress of Comparative Physiology and Biochemistry (ICCPB2011)  2011 

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    Presentation type:Oral presentation (invited, special)  

    Venue:Nagoya, Japan  

  • 受容タンパク質の多様性と光受容システムの進化 Invited Domestic conference

    小柳 光正

    日本遺伝学会第82回大会  2010 

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    Presentation type:Oral presentation (invited, special)  

  • 松果体における色識別と 光受容タンパク質の進化・多様性 Invited Domestic conference

    小柳 光正

    日本動物学会第81回大会  2010 

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    Presentation type:Oral presentation (invited, special)  

  • 受容タンパク質の進化と光受容の分子メカニズムの多様性 Invited Domestic conference

    小柳 光正

    11回光生物シンポジウム  2010 

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    Presentation type:Oral presentation (invited, special)  

  • Diverged members of rhodopsin family - molecular properties and functions. II - A new member from jellyfish Invited International conference

    KOYANAGI Mitsumasa

    13th Congress of the European Society for Photobiology  2009 

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    Presentation type:Oral presentation (invited, special)  

    Venue:Wroclaw, Poland  

  • 多様なロドプシン類の性質と光スイッチへの適性 Invited Domestic conference

    小柳 光正

    生理学研究所研究会  2009 

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    Presentation type:Oral presentation (invited, special)  

  • Diversity and evolution of the animal phototransduction cascade Invited International conference

    KOYANAGI Mitsumasa

    4th Asia and Oceania Conference on Photobiology (AOCP)  2008 

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    Presentation type:Oral presentation (invited, special)  

    Venue:Varanasi, India  

  • オプシンから見た光受容システムの進化 Invited Domestic conference

    小柳 光正

    日本進化学会第9回大会  2007 

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    Presentation type:Oral presentation (invited, special)  

  • ナメクジウオが語る脊椎動物の光受容系の進化 Invited Domestic conference

    小柳 光正

    東京大学海洋研究所共同利用研究集会  2007 

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    Presentation type:Oral presentation (invited, special)  

  • 光受容タンパク質の機能多様性の生理生化学的、進化学的研究 Invited Domestic conference

    小柳 光正

    日本比較生理生化学会第28回大会  2006 

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    Presentation type:Oral presentation (invited, special)  

  • 双安定性UV光受容分子の創造 Invited Domestic conference

    小柳 光正

    CREST領域第4回若手研究討論会  2005 

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    Presentation type:Oral presentation (invited, special)  

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Grant-in-Aid for Scientific Research

  • ロドプシンを用いたGPCR関連生理機能の新しい探索ストラテジー

    Grant-in-Aid for Challenging Research (Pioneering)/(Exploratory)  2022

  • 眼の進化におけるシンギュラリティ現象の解析

    Grant-in-Aid for Scientific Research on Innovative Areas  2022

  • 機能未知眼外光受容タンパク質に着目した哺乳類の脳内光受容の解明

    Grant-in-Aid for Scientific Research(B)  2022

  • 眼の進化におけるシンギュラリティ現象の解析

    Grant-in-Aid for Scientific Research on Innovative Areas  2021.04

  • A new strategy for investigating GPCR-based physiologies by using rhodopsins

    Grant-in-Aid for Challenging Research (Pioneering)/(Exploratory)  2020.07

  • 機能未知光受容タンパク質に着目した脊椎動物の脳内光受容とその多様性の解明

    Grant-in-Aid for Scientific Research(B)  2018.04

  • 光刺激を用いたシグナル伝達の時空間的に精密な制御

    Grant-in-Aid for Scientific Research on Innovative Areas  2017.04

  • 入力系の再構成によるオーファン受容体の出力の解析

    Grant-in-Aid for Scientific Research(B)  2016.07

  • Study on a non-visual photoreception lost in the course of mammalian evolution

    Grant-in-Aid for Challenging Research (Pioneering)/(Exploratory)  2015.04

  • Investigation of the diversity of visual and non-visual UV reception in jumping spiders

    Grant-in-Aid for Scientific Research(B)  2014.04

  • Functional analysis of genetic variation in melanoposin, a non-visual photoreceptor protein for circadian photoentrainment and its implication for phenotype

    Grant-in-Aid for Challenging Research (Pioneering)/(Exploratory)  2011

  • Investigation of the pineal wavelength discrimination in lower vertebrates

    Grant-in-Aid for Young Scientists(A)  2010.04

  • Functional analyses of rhodops in-related non-visual photopigments at molecular and neural levels.

    Grant-in-Aid for Young Scientists(B)  2008

  • Photoreceptome解析による動物の光受容システムの進化及び多様性の研究

    Grant-in-Aid for Scientific Research on Priority Areas  2006

  • Photoreceptome研究による動物の光受容システムの起源及び多様性の解明

    Grant-in-Aid for Scientific Research on Priority Areas  2005

  • 頭索類ナメクジウオにおける7つのロドプシン類似光受容蛋白質の機能多様性の解明

    Grant-in-Aid for JSPS Fellows  2002

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Contract research

  • 光の色を使った細胞内情報伝達因子の時空間的に精密な制御

    科学技術振興機構  2013.10

Other subsidies, etc.

  • 光受容タンパク質を用いた新しいGPCR研究ストラテジーの確立

    大学  2020.04

  • 光受容タンパク質を利用した生理応答の遠隔光操作

    大学  2019.04

  • 動物の光受容タンパク質を用いた生体ダメージのない生理応答の光操作

    大学  2018.04

Outline of education staff

  • 生命機能に重要な役割を果たすタンパク質について、その多様性を系統的に理解することを目指す。

Charge of on-campus class subject

  • 生物分子機能学演習

    2021     Graduate school

  • 前期特別研究

    2021     Graduate school

  • 後期特別研究

    2021     Graduate school

  • 特別研究

    2021     Undergraduate

  • 専門生物学演習

    2021     Undergraduate

  • 専門生物学実験B

    2021     Undergraduate

  • 生物学実験B

    2021     Undergraduate

  • 生体高分子機能学特論Ⅰ

    2021   Weekly class   Graduate school

  • 生物化学II

    2021   Weekly class   Undergraduate

  • 生命と進化

    2021   Weekly class   Undergraduate

  • 生物化学II

    2020     Undergraduate

  • 専門生物学実験B

    2020     Undergraduate

  • 専門生物学演習

    2020     Undergraduate

  • 特別研究

    2020     Undergraduate

  • 後期特別研究

    2020     Graduate school

  • 前期特別研究

    2020     Graduate school

  • 生物分子機能学演習

    2020     Graduate school

  • 生体高分子機能学特論Ⅰ

    2020     Graduate school

  • 生命と進化

    2020     Undergraduate

  • 生物学実験B

    2020     Undergraduate

  • 生物化学II

    2019     Undergraduate

  • 専門生物学演習

    2019     Undergraduate

  • 特別研究

    2019     Undergraduate

  • 後期特別研究

    2019     Graduate school

  • 前期特別研究

    2019     Graduate school

  • 生物分子機能学演習

    2019     Graduate school

  • 生体高分子機能学特論Ⅰ

    2019     Graduate school

  • 生命と進化

    2019     Undergraduate

  • 生物学実験B

    2019     Undergraduate

  • 専門生物学実験B

    2019     Undergraduate

  • 専門生物学演習

    2018     Undergraduate

  • 特別研究

    2018     Undergraduate

  • 後期特別研究

    2018     Graduate school

  • 前期特別研究

    2018     Graduate school

  • 生物分子機能学演習

    2018     Graduate school

  • 生体高分子機能学特論Ⅰ

    2018     Graduate school

  • 生命と進化

    2018     Undergraduate

  • 生物学実験B

    2018     Undergraduate

  • 専門生物学実験B

    2018     Undergraduate

  • 生物化学II

    2018     Undergraduate

  • 専門生物学演習

    2017     Undergraduate

  • 前期特別研究

    2017     Graduate school

  • 後期特別研究

    2017     Graduate school

  • 特別研究

    2017     Undergraduate

  • 生物分子機能学演習

    2017     Graduate school

  • 生体高分子機能学特論Ⅰ

    2017     Graduate school

  • 生命と進化

    2017     Undergraduate

  • 生物学実験B

    2017     Undergraduate

  • 専門生物学実験B

    2017     Undergraduate

  • 生物化学II

    2017     Undergraduate

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Charge of off-campus class subject

  • 感覚と応答の生物学

    2023.04
    -
    Now
    Institution:The Open University of Japan

Faculty development activities

  • FD活動への貢献  2022

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    学科内の多数回のFD関連会議に出席し、意見交換を行った。

  • FD活動への貢献  2021

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    学科内の多数回のFD関連会議に出席し、意見交換を行った。

  • FD活動への貢献  2020

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    学科内の多数回のFD関連会議に出席し、意見交換を行った。

  • FD活動への貢献  2019

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    学科内の多数回のFD関連会議に出席し、意見交換を行った。

  • FD活動への貢献  2018

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    学科内の多数回のFD関連会議に出席し、意見交換を行った。

  • FD活動への貢献  2017

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    学科内の多数回のFD関連会議に出席し、意見交換を行った。

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Number of papers published by graduate students

  • 2022

    Number of graduate students presentations:3

Social Activities

  • 第5回アカデミックカフェ

    Role(s): Lecturer

    大阪市立大学学術研究支援部研究推進課  2021.10

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    Audience: Junior high school students, High school students, University students, Graduate students, Teachers, Researchesrs, General public, Media

    Type:Science cafe

    Number of participants:105(人)

  • 市立高校による研究室見学

    Role(s): Host, Lecturer, Official expert, Performer

    2021.11

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    Audience: High school students

    Type:University open house

    Number of participants:15(人)

  • 第15回サイエンスカフェ高槻

    Role(s): Lecturer

    2018.05

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    Audience: Schoolchildren, Junior high school students, High school students, University students, General public

    Type:Science cafe

  • 動物が光を受け取るしくみと意外な使い道

    Role(s): Lecturer

    第15回サイエンスカフェ高槻  2018.05

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    Type:Lecture

Foreigner acceptance

  • 2022

    foreigners accepted :2

    International Students :0

  • 2021

    foreigners accepted :1

    International Students :0

  • 2020

    foreigners accepted :0

    International Students :1

  • 2019

    foreigners accepted :0

    International Students :1

  • 2018

    foreigners accepted :1

    International Students :1

  • 2017

    foreigners accepted :1

    International Students :1

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International exchange activities

  • オプシンの光遺伝学的利用と構造・機能に関する共同研究

    Field category :Research

    Country name :UK   2017 - Now

  • オプシンの光遺伝学的利用と構造・機能に関する共同研究

    Field category :Research

    Country name :USA   2017 - Now

  • オプシンの光遺伝学的利用と構造・機能に関する共同研究

    Field category :Research

    Country name :France   2017 - Now

  • オプシンの光遺伝学的利用と構造・機能に関する共同研究

    Field category :Research

    Country name :Belgium   2017 - Now

  • オプシンの多様性と構造多様性に関する共同研究

    Field category :Research

    Country name :Switzerland   2017 - Now

Job title

  • Manager within the university

    Researcher  2015.04

Other

  • Job Career

    2022.04 - Now

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    Osaka Metropolitan University Graduate School of Science Professor

  • Job Career

    2019.10 - 2022.03

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    Osaka City University Graduate School of Science Professor

  • Job Career

    2015.04 - Now

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    Osaka City University OCARINA Researcher (Concurrent)

  • Job Career

    2010.10 - 2019.09

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    Osaka City University Graduate School of Science Associate Professor

  • Job Career

    2006.04 - 2010.09

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    Osaka City University Graduate School of Science Lecturer