Updated on 2024/07/12

写真a

 
SHOJI Tetsuo
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Associate Professor
School of Medicine Department of Medical Science
Title
Associate Professor
Affiliation
Institute of Medicine
Profile
1985年 大阪市立大学医学部 卒業 1987年 国立循環器病センター研究所病因部(山本 章部長) 1991年 大阪市立大学医学部大学院 修了(医学博士) 1992年 米国ペニントン医学生物学研究所(G.A.Bray所長) 2012年 大阪市立大学大学院医学研究科 老年血管病態学 准教授 2016年 同 血管病態制御学 准教授 2018年 同 血管病態制御学 研究教授、現在に至る

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Associate Professor  2022.04 - Now

  • School of Medicine Department of Medical Science 

    Associate Professor  2022.04 - Now

Degree

  • Doctor of Medicine, Doctor of Philosophy ( Osaka City University )

Research Areas

  • Life Science / Metabolism and endocrinology  / Metabolic Science

  • Life Science / Nephrology  / Internal Medicine of Kidney

Research Interests

  • dyslipidemia

  • Mineral metabolism

  • chronic kidney disease

  • diabetes mellitus

  • atherosclerosis

  • vascular changes

  • Cognitive function

Research subject summary

  • Metabolic alterations in lipids and minerals affecting vascular changes in patients with diabetes mellitus and/or chronic kidney disease

Research Career

Professional Memberships

  • 日本動脈硬化学会

      Domestic

  • 日本糖尿病学会

      Domestic

  • 日本透析医学会

      Domestic

  • Japanese Society of Nephrology

      Domestic

  • European Renal Association-European Dialysis Transplantation Association

      Overseas

  • American Society of Nephrology

      Overseas

  • International Society of Nephrology

      Overseas

▼display all

Committee Memberships (off-campus)

  • 透析患者における心血管合併症の評価と治療に関するガイドライン(2011)作成委員会   日本透析医学会  

  • 慢性腎臓病に伴う骨・ミネラル代謝異常の診療ガイドライン(2012)作成委員会   日本透析医学会  

  • 慢性腎臓病の脂質管理のためのKDIGO診療ガイドライン(2012)作成委員会   KDIGO  

  • 動脈硬化性疾患予防ガイドライン(2012)作成委員会   日本動脈硬化学会  

  • エビデンスに基づくCKD診療ガイドライン(2013)作成委員会   日本腎臓学会  

  • 脳心血管病予防に関する包括的リスク管理チャート(2015)作成委員会   脳心血管病予防に関する包括的リスク管理合同会議  

  • 動脈硬化性疾患予防ガイドライン(2017)作成委員会   日本動脈硬化学会  

  • 脳心血管病予防に関する包括的リスク管理チャート(2019)作成委員会   脳心血管病予防に関する包括的リスク管理合同会議  

  • 動脈硬化性疾患予防ガイドライン(2022)作成委員会   日本動脈硬化学会  

    2020.02 - 2022.07 

  • 専門委員   独立行政法人医薬品医療機器総合機構  

    2019.06 - 2023.03 

▼display all

Awards

  • 日本透析医学会学会賞(木本賞)受賞

    2002  

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    Country:Japan

  • 大阪市医学会市長賞

    2004  

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    Country:Japan

  • Osaka City University Medical School Dean Award of Excellence

    2019.03  

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    Country:Japan

  • 日本透析医学会学会賞(木本賞)

    2019.06  

Education

  • Osaka City University     Graduated/Completed

    1979.04 - 1985.03

  • Osaka City University   Doctor's Course  

    - 1991

Papers

  • Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial. Invited Reviewed

    J-DAVID Investigators, Shoji T, Inaba M, Fukagawa M, Ando R, Emoto M, Fujii H, Fujimori A, Fukui M, Hase H, Hashimoto T, Hirakata H, Honda H, Hosoya T, Ikari Y, Inaguma D, Inoue T, Isaka Y, Iseki K, Ishimura E, Itami N, Ito C, Kakuta T, Kawai T, Kawanishi H, Kobayashi S, Kumagai J, Maekawa K, Masakane I, Minakuchi J, Mitsuiki K, Mizuguchi T, Morimoto S, Murohara T, Nakatani T, Negi S, Nishi S, Nishikawa M, Ogawa T, Ohta K, Ohtake T, Okamura M, Okuno S, Shigematsu T, Sugimoto T, Suzuki M, Tahara H, Takemoto Y, Tanaka K, Tominaga Y, Tsubakihara Y, Tsujimoto Y, Tsuruya K, Ueda S, Watanabe Y, Yamagata K, Yamakawa T, Yano S, Yokoyama K, Yorioka N, Yoshiyama M, Nishizawa Y

    JAMA   320 ( 22 )   2325 - 2334   2018.12( ISSN:0098-7484

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1001/jama.2018.17749

    PubMed

  • The heart and vascular system in dialysis. Invited Reviewed

    Wanner C, Amann K, Shoji T

    Lancet (London, England)   388 ( 10041 )   276 - 84   2016.07( ISSN:0140-6736

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1016/S0140-6736(16)30508-6

    PubMed

  • Association of Kidney Function with Serum Levels of Cholesterol Absorption and Synthesis Markers: The CACHE Study CKD Analysis. Invited Reviewed

    Shoji T, Akiyama Y, Fujii H, Harada-Shiba M, Ishibashi Y, Ishida T, Ishigaki Y, Kabata D, Kihara Y, Kotani K, Kurisu S, Masuda D, Matoba T, Matsuki K, Matsumura T, Mori K, Nakagami T, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Yoshida H

    Journal of atherosclerosis and thrombosis   29 ( 12 )   1835 - 1848   2022.12( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.63311

    PubMed

  • Comparative Effects of Etelcalcetide and Maxacalcitol on Serum Calcification Propensity in Secondary Hyperparathyroidism: A Randomized Clinical Trial. Invited Reviewed

    Shoji T, Nakatani S, Kabata D, Mori K, Shintani A, Yoshida H, Takahashi K, Ota K, Fujii H, Ueda S, Nishi S, Nakatani T, Yoshiyama M, Goto K, Hamada T, Imanishi M, Ishimura E, Kagitani S, Kato Y, Kumeda Y, Maekawa K, Matsumura T, Nagayama H, Obi Y, Ohno Y, Sai Y, Sakurai M, Sasaki S, Shidara K, Shoji S, Tsujimoto Y, Yamakawa K, Yasuda H, Yodoi S, Inaba M, Emoto M

    Clinical journal of the American Society of Nephrology : CJASN   16 ( 4 )   599 - 612   2021.04( ISSN:1555-9041

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.2215/CJN.16601020

    PubMed

  • Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. Invited Reviewed

    Shoji T, Emoto M, Shinohara K, Kakiya R, Tsujimoto Y, Kishimoto H, Ishimura E, Tabata T, Nishizawa Y

    Journal of the American Society of Nephrology : JASN   12 ( 10 )   2117 - 2124   2001.10( ISSN:1046-6673

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1681/ASN.V12102117

    PubMed

  • Multicenter randomized controlled trial of intensive uric acid lowering therapy for CKD patients with hyperuricemia: TARGET-UA. Invited Reviewed

    Yamamoto T, Kasahara M, Ueshima K, Uemura S, Kashihara N, Kimura K, Konta T, Shoji T, Mima A, Mukoyama M, Saito Y

    Clinical and experimental nephrology   2024.03( ISSN:1342-1751

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10157-024-02483-w

    PubMed

  • Differential associations of fetuin-A and calcification propensity with cardiovascular events and subsequent mortality in patients undergoing hemodialysis. Invited Reviewed

    Mori K, Shoji T, Nakatani S, Uedono H, Ochi A, Yoshida H, Imanishi Y, Morioka T, Tsujimoto Y, Kuro-O M, Emoto M

    Clinical kidney journal   17 ( 3 )   sfae042   2024.03( ISSN:2048-8505

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work   International / domestic magazine:International journal  

    DOI: 10.1093/ckj/sfae042

    PubMed

  • Patient-reported difficulty in activities of daily living and corresponding muscle weakness in elderly patients undergoing haemodialysis. Reviewed

    Matsufuji S, Shoji T, Lee S, Hoshio A, Tanaka R, Fujimoto K, Watanuki H, Nishimura M, Tsujimoto Y, Morioka T, Mori K, Emoto M

    Nephrology (Carlton, Vic.)   2024.02( ISSN:1320-5358

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work   International / domestic magazine:International journal  

    DOI: 10.1111/nep.14279

    PubMed

  • 【ガイドライン改訂で変わる 糖尿病関連腎臓病(DKD)診療】(第2章)糖尿病関連腎臓病の治療 薬物療法 脂質管理 Invited

    庄司 哲雄

    jmed mook   ( 90 )   59 - 63   2024.02

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    Publishing type:Research paper (scientific journal)  

    <ポイント>▼日本動脈硬化学会診療ガイドラインでは,糖尿病性腎症(糖尿病関連腎臓病)患者における脂質管理目標値はLDL-C<100mg/dL,Non-HDL-C<130mg/dL,空腹時トリグリセライド(triglyceride;TG)<150(非空腹時で<175)mg/dL,HDL-C≧40mg/dLと示されている。▼LDL-C,Non-HDL-C管理には,スタチン単独あるいはスタチン・エゼチミブ併用が推奨されている。▼腎機能が低下した患者のTG管理目的には,n-3系多価不飽和脂肪酸製剤あるいは選択的ペルオキシソーム増殖剤活性化受容α(peroxisome proliferator-activated receptor alpha;PPARα)モジュレーターが考慮される。(著者抄録)

  • Prosthesis use and the change in activities of daily living following below-knee amputation in patients undergoing hemodialysis. Invited Reviewed

    Yamazaki H, Matsufuji S, Nishikawa A, Ashida M, Yamaguchi M, Sato M, Tanimura N, Tsujimoto Y, Ubai T, Shoji T

    Hemodialysis international. International Symposium on Home Hemodialysis   28 ( 1 )   107 - 116   2024.01( ISSN:1492-7535

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hdi.13116

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  • Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022. Invited Reviewed

    Okamura T, Tsukamoto K, Arai H, Fujioka Y, Ishigaki Y, Koba S, Ohmura H, Shoji T, Yokote K, Yoshida H, Yoshida M, Deguchi J, Dobashi K, Fujiyoshi A, Hamaguchi H, Hara M, Harada-Shiba M, Hirata T, Iida M, Ikeda Y, Ishibashi S, Kanda H, Kihara S, Kitagawa K, Kodama S, Koseki M, Maezawa Y, Masuda D, Miida T, Miyamoto Y, Nishimura R, Node K, Noguchi M, Ohishi M, Saito I, Sawada S, Sone H, Takemoto M, Wakatsuki A, Yanai H

    Journal of atherosclerosis and thrombosis   2023.12( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.GL2022

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  • Serum Fibroblast Growth Factor 23 Levels are Associated with Vascular Smooth Muscle Dysfunction in Type 2 Diabetes(タイトル和訳中) Invited Reviewed

    Natsuki Yuka, Morioka Tomoaki, Kakutani Yoshinori, Yamazaki Yuko, Ochi Akinobu, Kurajoh Masafumi, Mori Katsuhito, Imanishi Yasuo, Shoji Tetsuo, Inaba Masaaki, Emoto Masanori

    Journal of Atherosclerosis and Thrombosis   30 ( 12 )   1838 - 1848   2023.12( ISSN:1340-3478

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  • Association of Serum Levels of Cholesterol Absorption and Synthesis Markers with the Presence of Cardiovascular Disease: The CACHE Study CVD Analysis(タイトル和訳中) Reviewed

    Katsuki Shunsuke, Matoba Tetsuya, Akiyama Yusuke, Yoshida Hiroshi, Kotani Kazuhiko, Fujii Hisako, Harada-Shiba Mariko, Ishibashi Yutaka, Ishida Tatsuro, Ishigaki Yasushi, Kabata Daijiro, Kihara Yasuki, Kurisu Satoshi, Masuda Daisaku, Matsuki Kota, Matsumura Takeshi, Mori Kenta, Nakagami Tomoko, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yoshida Hisako, Tsutsui Hiroyuki, Shoji Tetsuo

    Journal of Atherosclerosis and Thrombosis   30 ( 12 )   1766 - 1777   2023.12( ISSN:1340-3478

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    Authorship:Last author   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work   International / domestic magazine:International journal  

    Repository URL: http://hdl.handle.net/10466/0002000940

  • 【病因・病態生理から読み解く腎・泌尿器疾患のすべて】腎移植関連 生活習慣病 腎移植患者における脂質異常症 Invited

    中舎 璃乃, 庄司 哲雄

    腎と透析   95 ( 増刊 )   586 - 593   2023.12( ISSN:0385-2156

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    Publishing type:Research paper (scientific journal)  

  • Serum Values of Cholesterol Absorption and Synthesis Biomarkers in Japanese Healthy Subjects: The CACHE Study HEALTHY Analysis(タイトル和訳中) Invited Reviewed

    Ishibashi Yutaka, Yoshida Hiroshi, Kotani Kazuhiko, Akiyama Yusuke, Fujii Hisako, Harada-Shiba Mariko, Ishida Tatsuro, Ishigaki Yasushi, Kabata Daijiro, Kihara Yasuki, Kurisu Satoshi, Masuda Daisaku, Matoba Tetsuya, Matsuki Kota, Matsumura Takeshi, Mori Kenta, Nakagami Tomoko, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yano Shozo, Yoshida Hisako, Shoji Tetsuo

    Journal of Atherosclerosis and Thrombosis   30 ( 10 )   1336 - 1349   2023.10( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

  • 透析患者の日常生活動作(ADL) Invited Reviewed

    松藤 勝太, 庄司 哲雄, 李 寿恵, 山口 勝生, 辻本 吉広, 繪本 正憲

    大阪透析研究会会誌   40 ( 2 )   99 - 105   2023.09( ISSN:0912-6937

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    Publishing type:Research paper (scientific journal)  

  • 【CKD-MBDの新しい潮流】CKD-MBD治療 CKD-MBD管理の新たな知見 カルシウム受容体作動薬と血清石灰化傾向 Invited Reviewed

    庄司 哲雄

    腎と透析   95 ( 3 )   405 - 410   2023.09( ISSN:0385-2156

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    Publishing type:Research paper (scientific journal)  

    <文献概要>はじめに カルシウム受容体作動薬は副甲状腺細胞膜のカルシウム受容体(calcium-sensing receptor:CaS-R)に結合して,細胞外カルシウム濃度が高いようにシグナルを入れることにより,副甲状腺ホルモン(parathyroid hormone:PTH)の分泌を抑制する薬剤である。あたかもカルシウムのようにふるまうためカルシミメティクスとも呼ばれ,二次性副甲状腺機能亢進症(secondary hyperparathyroidism:SHPT)治療に用いられている。本稿では,SHIPT治療下におけるカルシウム受容体作動薬と活性型ビタミンD製剤[あるいはビタミンD受容体作動薬(vitamin D receptor activator:VDRA)]の位置づけを考えるうえで,血清石灰化傾向(serum calcification propensity:T50)への影響の違いなどを概説する。

  • Association between Familial Hypercholesterolemia and Serum Levels of Cholesterol Synthesis and Absorption Markers: The CACHE Study FH Analysis(タイトル和訳中) Invited Reviewed

    Matsuki Kota, Harada-Shiba Mariko, Hori Mika, Ogura Masatsune, Akiyama Yusuke, Fujii Hisako, Ishibashi Yutaka, Ishida Tatsuro, Ishigaki Yasushi, Kabata Daijiro, Kihara Yasuki, Kotani Kazuhiko, Kurisu Satoshi, Masuda Daisaku, Matoba Tetsuya, Matsumura Takeshi, Mori Kenta, Nakagami Tomoko, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yoshida Hiroshi, Yoshida Hisako, Shoji Tetsuo

    Journal of Atherosclerosis and Thrombosis   30 ( 9 )   1152 - 1164   2023.09( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

  • 動脈硬化性疾患予防ガイドライン2022のエッセンス Invited Reviewed

    庄司 哲雄

    循環器内科   94 ( 2 )   175 - 178   2023.08( ISSN:1884-2909

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    Publishing type:Research paper (scientific journal)  

  • Serum Fibroblast Growth Factor 23 Levels are Associated with Vascular Smooth Muscle Dysfunction in Type 2 Diabetes. Invited Reviewed

    Natsuki Y, Morioka T, Kakutani Y, Yamazaki Y, Ochi A, Kurajoh M, Mori K, Imanishi Y, Shoji T, Inaba M, Emoto M

    Journal of atherosclerosis and thrombosis   2023.05( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.64000

    PubMed

  • Association of Serum Levels of Cholesterol Absorption and Synthesis Markers with the Presence of Cardiovascular Disease: The CACHE Study CVD Analysis. Invited Reviewed

    Katsuki S, Matoba T, Akiyama Y, Yoshida H, Kotani K, Fujii H, Harada-Shiba M, Ishibashi Y, Ishida T, Ishigaki Y, Kabata D, Kihara Y, Kurisu S, Masuda D, Matsuki K, Matsumura T, Mori K, Nakagami T, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Tsutsui H, Shoji T

    Journal of atherosclerosis and thrombosis   2023.04( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.64119

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  • Serum phosphate as an independent factor associated with cholesterol metabolism in patients undergoing hemodialysis: a cross-sectional analysis of the DREAM cohort. Reviewed

    Okute Y, Shoji T, Shimomura N, Tsujimoto Y, Nagata Y, Uedono H, Nakatani S, Morioka T, Mori K, Fukumoto S, Imanishi Y, Emoto M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   38 ( 4 )   1002 - 1008   2023.03( ISSN:0931-0509

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1093/ndt/gfac222

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    Repository URL: http://hdl.handle.net/10466/0002000412

  • Trajectory of Serum Albumin Prior to Death in Patients Receiving Hemodialysis. Invited Reviewed

    Suzuki Y, Harada M, Matsuzawa R, Hoshi K, Koh YM, Aoyama N, Uemura K, Yamamoto S, Imamura K, Yoshikoshi S, Kamiya K, Yoshida A, Shoji T, Matsunaga A

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   33 ( 2 )   368 - 375   2023.03( ISSN:1051-2276

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/j.jrn.2022.07.007

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  • Serum Values of Cholesterol Absorption and Synthesis Biomarkers in Japanese Healthy Subjects: The CACHE Study HEALTHY Analysis. Invited Reviewed

    Ishibashi Y, Yoshida H, Kotani K, Akiyama Y, Fujii H, Harada-Shiba M, Ishida T, Ishigaki Y, Kabata D, Kihara Y, Kurisu S, Masuda D, Matoba T, Matsuki K, Matsumura T, Mori K, Nakagami T, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yano S, Yoshida H, Tetsuo S

    Journal of atherosclerosis and thrombosis   2023.02( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.63943

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  • 【プライマリ・ケアにも役立つ続発性内分泌代謝異常の診断・治療】CKD・ネフローゼ症候群による脂質異常症 Invited Reviewed

    庄司 哲雄

    糖尿病・内分泌代謝科   56 ( 2 )   164 - 168   2023.02( ISSN:2435-1946

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    Publishing type:Research paper (scientific journal)  

  • Association between Familial Hypercholesterolemia and Serum Levels of Cholesterol Synthesis and Absorption Markers: The CACHE Study FH Analysis. Invited Reviewed

    Matsuki K, Harada-Shiba M, Hori M, Ogura M, Akiyama Y, Fujii H, Ishibashi Y, Ishida T, Ishigaki Y, Kabata D, Kihara Y, Kotani K, Kurisu S, Masuda D, Matoba T, Matsumura T, Mori K, Nakagami T, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Yoshida H, Shoji T

    Journal of atherosclerosis and thrombosis   2023.01( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.63899

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  • T50(血清石灰化傾向) 石灰化ストレスの指標 Invited Reviewed

    庄司 哲雄, 仲谷 慎也, 上殿 英記, 永倉 優, 永田 友貴, 森岡 与明, 森 克仁, 繪本 正憲

    腎臓内科   17 ( 1 )   104 - 111   2023.01( ISSN:2435-1903

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    Publishing type:Research paper (scientific journal)  

  • 【慢性腎臓病における血管石灰化の病態と治療】基礎と臨床の両面から Fetuin-Aと血管石灰化 Invited Reviewed

    森 克仁, 仲谷 慎也, 上殿 英記, 庄司 哲雄

    腎臓内科   17 ( 1 )   15 - 20   2023.01( ISSN:2435-1903

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  • Improvement in the mobility of a patient with fibroblast growth factor 23-related hypophosphatemic osteomalacia and decompensated liver cirrhosis in response to burosumab: a case report. Invited Reviewed

    Toi N, Imanishi Y, Nagata Y, Kurajoh M, Morioka T, Shoji T, Shinto Y, Emoto M

    Endocrine journal   2022.12( ISSN:0918-8959

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1507/endocrj.EJ22-0520

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  • Association of Kidney Function with Serum Levels of Cholesterol Absorption and Synthesis Markers: The CACHE Study CKD Analysis(和訳中) Invited Reviewed

    Shoji Tetsuo, Akiyama Yusuke, Fujii Hisako, Harada-Shiba Mariko, Ishibashi Yutaka, Ishida Tatsuro, Ishigaki Yasushi, Kabata Daijiro, Kihara Yasuki, Kotani Kazuhiko, Kurisu Satoshi, Masuda Daisaku, Matoba Tetsuya, Matsuki Kota, Matsumura Takeshi, Mori Kenta, Nakagami Tomoko, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yoshida Hisako, Yoshida Hiroshi

    Journal of Atherosclerosis and Thrombosis   29 ( 12 )   1835 - 1848   2022.12( ISSN:1340-3478

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  • 【透析患者の認知症-診断・予防・治療・見合わせ・CKM】透析患者の認知症の危険因子とその予防 Invited Reviewed

    庄司 哲雄

    臨床透析   38 ( 13 )   1614 - 1623   2022.12( ISSN:0910-5808

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    <文献概要>透析患者の認知症あるいは認知機能低値に関連する因子の同定は予防に役立つ可能性がある.年齢,糖尿病,脳卒中既往,教育歴は認知症・認知機能に関連する.透析年数が長いと認知症が少ない,あるいは認知症になるリスクが低いという報告がある.高血圧や収縮期血圧は関連を示さないが,拡張期血圧低値が認知機能低値と関連する.CKD-MBD治療歴のない患者はCKD-MBD治療歴のある患者に比較し認知症新規発症リスクが高い.

  • 【透析患者の認知症-診断・予防・治療・見合わせ・CKM】透析患者における認知症の疫学と特徴 Invited Reviewed

    佐々木 けやき, 庄司 哲雄

    臨床透析   38 ( 13 )   1601 - 1607   2022.12( ISSN:0910-5808

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    <文献概要>認知症は成因によって,脳血管障害が原因となる血管性認知症,神経変性を背景とする変性性認知症(アルツハイマー型,レビー小体型認知症など)に大別される.一般住民における有病率は,アルツハイマー型認知症が最多であり,血管性認知症,レビー小体型認知症/認知症を伴うパーキンソン病と続く.透析患者を含めた慢性腎臓病では一般住民に比べて認知機能障害の有病率が高く,血管障害との関連が想定されてきたが,認知症病型別の詳細な報告は少ない.透析年数と認知症発症との間に負の関連性が認められるなど,透析患者における認知症の実態・成因についてさらなる情報蓄積が必要である.

  • Associations of time-dependent changes in phosphorus levels with cardiovascular diseases in patients undergoing hemodialysis: results from the Japan Dialysis Active Vitamin D (J-DAVID) randomized clinical trial. Invited Reviewed

    Koshi-Ito E, Inaguma D, Ishii H, Yuzawa Y, Kabata D, Shintani A, Inaba M, Emoto M, Mori K, Morioka T, Nakatani S, Shoji T

    Clinical kidney journal   15 ( 12 )   2281 - 2291   2022.12( ISSN:2048-8505

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    DOI: 10.1093/ckj/sfac172

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  • Nutritional Disorder Evaluated by the Geriatric Nutritional Risk Index Predicts Death After Hospitalization for Infection in Patients Undergoing Maintenance Hemodialysis. Invited Reviewed

    Machiba Y, Mori K, Shoji T, Nagata Y, Uedono H, Nakatani S, Ochi A, Tsuda A, Morioka T, Yoshida H, Tsujimoto Y, Emoto M

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   32 ( 6 )   751 - 757   2022.11( ISSN:1051-2276

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    DOI: 10.1053/j.jrn.2022.01.008

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  • Reduced Risk of Progression from Non-Severe to Severe COVID-19 in Hospitalized Dialysis Patients by Full COVID-19 Vaccination. Invited Reviewed

    Ichii M, Kurajoh M, Okute Y, Ihara Y, Imai T, Morioka T, Mori K, Shoji T, Tsujimoto Y, Ubai T, Emoto M

    Journal of clinical medicine   11 ( 21 )   2022.10( ISSN:2077-0383

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    DOI: 10.3390/jcm11216348

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  • Acute Kidney Injury and Remission of Proteinuria in Minimal Change Disease. Invited Reviewed

    Yamamoto R, Imai E, Maruyama S, Yokoyama H, Sugiyama H, Takeda A, Uchida S, Tsukamoto T, Tsuruya K, Akai Y, Nitta K, Fukunaga M, Hayashi H, Shoji T, Masutani K, Konta T, Katafuchi R, Nishio S, Wada T, Goto S, Tamai H, Shirasaki A, Nagai K, Nishino T, Yamagata K, Kazama JJ, Hiromura K, Yasuda H, Sofue T, Fujimoto S, Mizutani M, Naruse T, Hiramatsu T, Morozumi K, Sobajima H, Saka Y, Ishimura E, Ito T, Ichikawa D, Shigematsu T, Sato H, Narita I, Yoshitaka I, Japan Nephrotic Syndrome Cohort Study investigators

    Kidney international reports   7 ( 10 )   2283 - 2288   2022.10

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    DOI: 10.1016/j.ekir.2022.07.173

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  • Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis. Invited Reviewed

    Matsumura T, Ishigaki Y, Nakagami T, Akiyama Y, Ishibashi Y, Ishida T, Fujii H, Harada-Shiba M, Kabata D, Kihara Y, Kotani K, Kurisu S, Masuda D, Matoba T, Matsuki K, Mori K, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Yoshida H, Shoji T

    Journal of atherosclerosis and thrombosis   2022.09( ISSN:1340-3478

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    DOI: 10.5551/jat.63725

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  • Effects of alfacalcidol on cardiovascular outcomes according to alkaline phosphatase levels in the J-DAVID trial. Invited Reviewed

    Oka T, Sakaguchi Y, Isaka Y, Ishii H, Kabata D, Shintani A, Nakatani S, Morioka T, Mori K, Inaba M, Emoto M, Shoji T

    Scientific reports   12 ( 1 )   15463   2022.09

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    DOI: 10.1038/s41598-022-19820-2

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  • Associations of cardiovascular disease and blood pressure with cognition in hemodialysis patients: The Osaka Dialysis Complication Study. Invited Reviewed

    Shoji T, Fujii H, Mori K, Nakatani S, Nagata Y, Morioka T, Inaba M, Emoto M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   37 ( 9 )   1758 - 1767   2022.08( ISSN:0931-0509

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    DOI: 10.1093/ndt/gfab247

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  • Complete Right Bundle Branch Block as a Predictor of Cardiovascular Events in Type 2 Diabetes. Invited Reviewed

    Ono K, Uchimoto S, Miyazaki M, Honda N, Mori K, Morioka T, Imai T, Shoji T, Emoto M

    Journal of clinical medicine   11 ( 15 )   2022.08( ISSN:2077-0383

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    DOI: 10.3390/jcm11154618

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  • Associations of Serum Insulin-Like Growth Factor 1 with New Cardiovascular Events and Subsequent Death in Hemodialysis Patients: The DREAM Cohort. Invited Reviewed

    Nakaya R, Shoji T, Nagata Y, Nakatani S, Mori K, Morioka T, Tsujimoto Y, Emoto M

    Journal of atherosclerosis and thrombosis   29 ( 8 )   1153 - 1165   2022.08( ISSN:1340-3478

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    DOI: 10.5551/jat.62992

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  • Associations of Serum Insulin-Like Growth Factor 1 with New Cardiovascular Events and Subsequent Death in Hemodialysis Patients: The DREAM Cohort(和訳中) Invited Reviewed

    Nakaya Rino, Shoji Tetsuo, Nagata Yuki, Nakatani Shinya, Mori Katsuhito, Morioka Tomoaki, Tsujimoto Yoshihiro, Emoto Masanori

    Journal of Atherosclerosis and Thrombosis   29 ( 8 )   1153 - 1165   2022.08( ISSN:1340-3478

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  • Factors associated with atrial fibrillation in Japanese patients with type 2 diabetes mellitus: a cross-sectional study. Invited Reviewed

    Honda N, Ochi A, Uchimoto S, Kakutani Y, Yamazaki Y, Morioka T, Shoji T, Inaba M, Emoto M

    Diabetology international   13 ( 3 )   503 - 512   2022.07( ISSN:2190-1678

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    DOI: 10.1007/s13340-021-00563-w

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  • 日本人2型糖尿病患者における心房細動の関連因子 横断研究(Factors associated with atrial fibrillation in Japanese patients with type 2 diabetes mellitus: a cross-sectional study) Invited Reviewed

    Honda Natsuki, Ochi Akinobu, Uchimoto Sadahiko, Kakutani Yoshinori, Yamazaki Yuko, Morioka Tomoaki, Shoji Tetsuo, Inaba Masaaki, Emoto Masanori

    Diabetology International   13 ( 3 )   503 - 512   2022.07( ISSN:2190-1678

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    日本人2型糖尿病(T2D)患者における心房細動(AF)の有病率とその関連因子を横断研究により検討した。T2D患者899例(男性518例、女性381例、平均69.0±12.1歳)を対象に、AF診断をシングルポイント標準12誘導心電図所見で行い、AF併存および非併存患者における年齢、性別、糖尿病期間、糖化ヘモグロビン、BMI、推算糸球体濾過率、アルブミン尿またはタンパク尿、ビグアニドの使用、高血圧の有無などの臨床パラメータを分析した。AF併存患者は53例(5.9%)(男性35例、女性18例、平均77.1±9.3歳)であった。年齢と共にAF有病率は高くなり、80歳以上の患者では男女ともにAF罹患率は8%以上であった。また全体的なAF有病率は女性よりも男性で高い傾向があり、さらにアルブミン尿やタンパク尿が進行しeGFRが低下するほど有病率が高くなった。多重ロジスティック回帰分析では、高齢、男性、eGFR低下が、AF併存と独立かつ有意に関連していたが、アルブミン尿やタンパク尿とAFには有意な関連が見られなかった。当該患者では、AFは腎機能低下と密接な関連があった。

  • 新型コロナウイルスワクチン接種後に発症した劇症1型糖尿病の1例(New-onset fulminant type 1 diabetes after severe acute respiratory syndrome coronavirus 2 vaccination: A case report) Invited Reviewed

    Sasaki Keyaki, Morioka Tomoaki, Okada Natsumi, Natsuki Yuka, Kakutani Yoshinori, Ochi Akinobu, Yamazaki Yuko, Shoji Tetsuo, Ohmura Takashi, Emoto Masanori

    Journal of Diabetes Investigation   13 ( 7 )   1286 - 1289   2022.07( ISSN:2040-1116

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    症例は45歳女性で、生来健康で糖尿病診断歴はなかった。新型コロナウイルスワクチン(BNT162b2)の1回目接種2日後に全身倦怠感と口渇を自覚した。同6日後に悪心と腹痛が出現し、同8日後に高血糖のため当院を紹介受診した。来院時検査で随時血糖344mg/dL、HbA1c 7.6%、アニオンギャップ開大(25.6mEq/L)を伴う代謝性アシドーシス、ケトン血症を認め、糖尿病性ケトアシドーシスの診断で入院となった。血清膵酵素高値、インスリン分泌枯渇、および膵島関連自己抗体陰性の所見から劇症1型糖尿病と診断した。HLA解析において、日本人劇症1型糖尿病の疾患感受性アレルDQB1*04:05およびDQB1*04:01が確認された。抗体検査で1型糖尿病関連ウイルスの感染は認められなかった。劇症1型糖尿病の遺伝的素因を有する場合には、新型コロナウイルスワクチン接種が発症の誘因となる可能性があると考えられた。

  • 【腎疾患におけるサルコペニア・フレイルの病態と臨床】サルコペニア・フレイルの発症機序とビタミンD Invited Reviewed

    奥手 祐治郎, 庄司 哲雄

    腎臓内科   16 ( 1 )   31 - 37   2022.07( ISSN:2435-1903

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  • New-onset fulminant type 1 diabetes after severe acute respiratory syndrome coronavirus 2 vaccination: A case report. Invited Reviewed

    Sasaki K, Morioka T, Okada N, Natsuki Y, Kakutani Y, Ochi A, Yamazaki Y, Shoji T, Ohmura T, Emoto M

    Journal of diabetes investigation   13 ( 7 )   1286 - 1289   2022.07( ISSN:2040-1116

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    DOI: 10.1111/jdi.13771

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  • Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study. Invited Reviewed

    Yamamoto R, Imai E, Maruyama S, Yokoyama H, Sugiyama H, Takeda A, Uchida S, Tsukamoto T, Tsuruya K, Akai Y, Nitta K, Fukunaga M, Hayashi H, Masutani K, Wada T, Konta T, Katafuchi R, Nishio S, Goto S, Tamai H, Shirasaki A, Shoji T, Nagai K, Nishino T, Yamagata K, Kazama JJ, Hiromura K, Yasuda H, Mizutani M, Naruse T, Hiramatsu T, Morozumi K, Sobajima H, Saka Y, Ishimura E, Ichikawa D, Shigematsu T, Sofue T, Fujimoto S, Ito T, Sato H, Narita I, Isaka Y, JNSCS Investigators

    Scientific reports   12 ( 1 )   9782   2022.06

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    DOI: 10.1038/s41598-022-13067-7

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  • 【腎代替療法のすべて】(第9章)透析患者の合併症 脂質異常症 Invited Reviewed

    庄司 哲雄

    腎と透析   92 ( 増刊 )   563 - 568   2022.06( ISSN:0385-2156

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  • Time to remission of proteinuria and incidence of relapse in patients with steroid-sensitive minimal change disease and focal segmental glomerulosclerosis: the Japan Nephrotic Syndrome Cohort Study. Invited Reviewed

    Yamamoto R, Imai E, Maruyama S, Yokoyama H, Sugiyama H, Takeda A, Tsukamoto T, Uchida S, Tsuruya K, Shoji T, Hayashi H, Akai Y, Fukunaga M, Konta T, Nishio S, Goto S, Tamai H, Nagai K, Katafuchi R, Masutani K, Wada T, Nishino T, Shirasaki A, Sobajima H, Nitta K, Yamagata K, Kazama JJ, Hiromura K, Yasuda H, Mizutani M, Akahori T, Naruse T, Hiramatsu T, Morozumi K, Mimura T, Saka Y, Ishimura E, Hasegawa H, Ichikawa D, Shigematsu T, Sato H, Narita I, Isaka Y, Japan Nephrotic Syndrome Cohort Study investigators

    Journal of nephrology   35 ( 4 )   1135 - 1144   2022.05( ISSN:1121-8428

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    DOI: 10.1007/s40620-022-01279-z

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  • 【予防医学からみた腎疾患診療】CKDの発症・進展と合併症を防止するための治療戦略と目標値 脂質異常症 Invited Reviewed

    庄司 哲雄

    腎と透析   92 ( 5 )   913 - 917   2022.05( ISSN:0385-2156

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  • Generation of Ultralong Liposome Tubes by Membrane Fusion beneath a Laser-Induced Microbubble on Gold Surfaces. Invited Reviewed

    Kojima C, Noguchi A, Nagai T, Yuyama KI, Fujii S, Ueno K, Oyamada N, Murakoshi K, Shoji T, Tsuboi Y

    ACS omega   7 ( 15 )   13120 - 13127   2022.04

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    DOI: 10.1021/acsomega.2c00553

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  • New-onset Type 1 Diabetes after COVID-19 mRNA Vaccination. Invited Reviewed

    Yano M, Morioka T, Natsuki Y, Sasaki K, Kakutani Y, Ochi A, Yamazaki Y, Shoji T, Emoto M

    Internal medicine (Tokyo, Japan)   61 ( 8 )   1197 - 1200   2022.04( ISSN:0918-2918

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    DOI: 10.2169/internalmedicine.9004-21

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  • COVID-19 mRNAワクチン接種後の新規発症1型糖尿病(New-onset Type 1 Diabetes after COVID-19 mRNA Vaccination) Invited Reviewed

    Yano Masahiro, Morioka Tomoaki, Natsuki Yuka, Sasaki Keyaki, Kakutani Yoshinori, Ochi Akinobu, Yamazaki Yuko, Shoji Tetsuo, Emoto Masanori

    Internal Medicine   61 ( 8 )   1197 - 1200   2022.04( ISSN:0918-2918

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    症例は51歳女性で、mRNA-1273 SARS-CoV-2ワクチンを初回接種した28日後、全身性疲労、口渇、多尿、多飲が出現した。発症後2日目に2回目のワクチン接種を行うと、症状が著明に悪化した。3kgの体重減少に気づいたため、発症後12日目にかかりつけ医を受診し、その2日後(初回ワクチン接種後6週目)に高血糖が判明して(随時血糖455mg/dL)、紹介来院した。来院時の所見では、軽度の脱水が示唆された。検査所見からHbA1c高値の高血糖が判明し、アニオンギャップ増加を伴う代謝性アシドーシスとケトン血症が認められたことから、糖尿病性ケトアシドーシスと診断した。精査の結果、内因性インスリン分泌の枯渇、インスリン自己抗体陽性、甲状腺自己免疫が判明した。1型糖尿病を惹起すると考えられる最近のウイルス感染の徴候は認めなかったことから、SARS-CoV-2ワクチン誘発性免疫が示唆された。ヒト白血球抗原クラスII遺伝子型分類の結果、DRB1*09:01-DQB1*03:03ハプロタイプのホモ接合が判明し、急性発症1型糖尿病と診断した。

  • 【ネフローゼ症候群update】合併症と対策 脂質異常症・耐糖能異常 Invited Reviewed

    仲谷 慎也, 庄司 哲雄

    腎と透析   92 ( 4 )   760 - 764   2022.04( ISSN:0385-2156

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  • Fluorescence Colour Control in Perylene-Labeled Polymer Chains Trapped by Nanotextured Silicon. Invited Reviewed

    Takao R, Ushiro K, Kusano H, Yuyama KI, Shoji T, Linklater DP, Ivanova E, Juodkazis S, Tsuboi Y

    Angewandte Chemie (International ed. in English)   61 ( 11 )   e202117227   2022.03( ISSN:1433-7851

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    DOI: 10.1002/anie.202117227

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  • リポ蛋白だけでは語れない脂質異常症 Invited Reviewed

    庄司 哲雄

    西宮市医師会医学雑誌   ( 27 )   9 - 13   2022.03( ISSN:1341-2574

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    リポ蛋白を中心に語られてきた脂質異常症は、血液中の「あぶら」の異常により何らかの病気のリスクを高めている状態である。スタチンやエゼチミブはLDL-C低下療法として脂質異常症の治療に用いられるが、それ以外のリポ蛋白では語れない機序が病態に影響している可能性がある。コレステロール吸収亢進が心血管リスクと関連する機序として、Niemann-Pick C1-Like 1を介したオキシステロール吸収の影響が背後に隠れている可能性がある。

  • Role of adiponectin in the relationship between visceral adiposity and fibroblast growth factor 23 in non-diabetic men with normal kidney function. Invited Reviewed

    Natsuki Y, Morioka T, Fukumoto S, Kakutani Y, Yamazaki Y, Ochi A, Kurajoh M, Mori K, Shoji T, Imanishi Y, Inaba M, Emoto M

    Endocrine journal   69 ( 2 )   121 - 129   2022.02( ISSN:0918-8959

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    DOI: 10.1507/endocrj.EJ21-0185

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  • 腎機能正常の非糖尿病男性における内臓脂肪と線維芽細胞増殖因子23の関連性におけるアディポネクチンの役割(Role of adiponectin in the relationship between visceral adiposity and fibroblast growth factor 23 in non-diabetic men with normal kidney function) Invited Reviewed

    Natsuki Yuka, Morioka Tomoaki, Fukumoto Shinya, Kakutani Yoshinori, Yamazaki Yuko, Ochi Akinobu, Kurajoh Masafumi, Mori Katsuhito, Shoji Tetsuo, Imanishi Yasuo, Inaba Masaaki, Emoto Masanori

    Endocrine Journal   69 ( 2 )   121 - 129   2022.02( ISSN:0918-8959

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    MedCity21健康診断レジストリに登録され、包括的健康診断を行った腎機能正常の非糖尿病成人189例(男性94例、女性95例、中央値52歳)を対象に、血清線維芽細胞増殖因子23(FGF23)と内臓脂肪および血清アディポネクチン(ADPN)の関連を横断的に検討した。男性は女性に比べて血清FGF23が有意に高値で、CT上の内臓脂肪面積(VFA)が有意に大きく、血清ADPNが有意に低値であった。男性において、血清FGF23はVFAと正相関し、これは年齢、推算糸球体濾過量、カルシウム・リン・intact副甲状腺ホルモン・1,25ジヒドロキシビタミンDの血清レベルを調整後も有意性が維持された。血清ADPNを共変量に含めた場合、血清ADPNは男性における血清FGF23の独立した決定因子であったが、VFAは決定因子ではなかった。ADPNは、男性における内臓脂肪とFGF23の関連性に重要な役割を有することが示唆された。

  • 腎機能障害を伴うネフローゼ症候群に対する低密度リポタンパク質アフェレーシスの良好な治療効果(Favorable therapeutic efficacy of low-density lipoprotein apheresis for nephrotic syndrome with impaired renal function) Invited Reviewed

    Muso Eri, Sakai Soichi, Ogura Youske, Yukawa Susumu, Nishizawa Yoshiki, Yorioka Noriaki, Saito Takao, Mune Masatoshi, Sugiyama Satoshi, Iino Yasuhiko, Hirano Tsutomu, Hattori Motoshi, Watanabe Tsuyoshi, Yokoyama Hitoshi, Sato Hiroshi, Uchida Shunya, Wada Takashi, Shoji Tetsuo, Oda Hiroaki, Mori Kiyoshi, Kimura Hideki, Ito Osamu, Nishiyama Akira, Maruyama Shoichi, Inagi Reiko, Fujimoto Shoichi, Tsukamoto Tatsuo, Suzuki Yusuke, Honda Hirokazu, Babazono Tetsuya, Tsuruya Kazuhiko, Yuzawa Yukio

    Therapeutic Apheresis and Dialysis   26 ( 1 )   220 - 228   2022.02( ISSN:1744-9979

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    腎機能障害を伴う薬物抵抗性ネフローゼ症候群(NS)に対する低密度リポタンパク質アフェレーシス(LDL-A)の効果を調べた前向き多施設コホート研究(POLARIS)の症例を対象に、治療前の推算糸球体濾過量(eGFR)別に、LDL-A治療効果を事後分析で評価した。当該研究におけるLDL-Aの45件を治療直後の短期有効性、43症例を治療2年後の長期有効性の評価に用いた。当該45件の患者群はeGFRに従って、腎機能正常群17件(N群)、中程度障害14件(M群)、重度障害14件(S群)に層別化して検討した。再発、巣状分節状糸球体硬化症、シクロスポリンA治療症例の割合はM群で低い傾向、抗凝固薬の使用はS群で高い傾向が見られた。LDL-A後ではタンパク尿(UP)と腎機能の有意な改善はN群とM群で見られ、S群では腎機能の有意な改善は見られなかったがUPの改善傾向が認められた。LDL-A治療後2年における治療成績をeGFRが30mL/min/1.73m2以上の群とそれ以下の群で比較した。その結果、両群のほとんどの症例が末期腎不全に移行していなかった。腎機能が30mL/min/1.73m2に低下した場合でも、LDL-Aが治療効果を有することが示唆された。

  • Favorable therapeutic efficacy of low-density lipoprotein apheresis for nephrotic syndrome with impaired renal function. Invited Reviewed

    Muso E, Sakai S, Ogura Y, Yukawa S, Nishizawa Y, Yorioka N, Saito T, Mune M, Sugiyama S, Iino Y, Hirano T, Hattori M, Watanabe T, Yokoyama H, Sato H, Uchida S, Wada T, Shoji T, Oda H, Mori K, Kimura H, Ito O, Nishiyama A, Maruyama S, Inagi R, Fujimoto S, Tsukamoto T, Suzuki Y, Honda H, Babazono T, Tsuruya K, Yuzawa Y

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   26 ( 1 )   220 - 228   2022.02( ISSN:1744-9979

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    DOI: 10.1111/1744-9987.13694

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  • Association between Levocarnitine Treatment and the Change in Knee Extensor Strength in Patients Undergoing Hemodialysis: A Post-Hoc Analysis of the Osaka Dialysis Complication Study (ODCS). Invited Reviewed

    Matsufuji S, Shoji T, Lee S, Yamaguchi M, Nishimura M, Tsujimoto Y, Nakatani S, Morioka T, Mori K, Emoto M

    Nutrients   14 ( 2 )   2022.01

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    DOI: 10.3390/nu14020343

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  • Dialysate calcium, alfacalcidol, and clinical outcomes: A post-hoc analysis of the J-DAVID trial. Invited Reviewed

    Iseki K, Kabata D, Shoji T, Inaba M, Emoto M, Mori K, Morioka T, Nakatani S, Shintani A

    PloS one   17 ( 9 )   e0273195   2022

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    DOI: 10.1371/journal.pone.0273195

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  • Association of Reduced Free T3 to Free T4 Ratio with Lower Serum Creatinine in Japanese Hemodialysis Patients. Invited Reviewed

    Inaba M, Mori K, Tsujimoto Y, Yamada S, Yamazaki Y, Emoto M, Shoji T

    Nutrients   13 ( 12 )   2021.12

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    DOI: 10.3390/nu13124537

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  • 血液透析中の患者における心血管イベントと総死亡率の予測因子としての遊離トリヨードチロニン低値 DREAMコホート(Low Free Triiodothyronine Level as a Predictor of Cardiovascular Events and All-Cause Mortality in Patients Undergoing Hemodialysis: The DREAM Cohort) Invited Reviewed

    Yamazaki Yuko, Shoji Tetsuo, Miyashima Masako, Nagata Yuki, Kakutani Yoshinori, Ochi Akinobu, Morioka Tomoaki, Nakatani Shinya, Mori Katsuhito, Tsujimoto Yoshihiro, Emoto Masanori

    Journal of Atherosclerosis and Thrombosis   28 ( 10 )   1071 - 1082   2021.10( ISSN:1340-3478

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    遊離トリヨードチロニン(FT3)低値が血液透析中の患者における心血管疾患イベントの独立予測因子であるかどうかを調べた。血液透析中の慢性腎疾患患者を対象に、血清FT3、遊離チロキシン、甲状腺刺激ホルモン値を測定した。5年間の経過観察を行い、心血管疾患の新規発症、死亡日と死亡原因を評価した。438例をFT3値の三分位で最低FT3群171例(男性56.7%、中央値63歳)、中等度FT3群103例(男性68.0%、中央値63歳)、最高FT3群164例(男性68.3%、中央値57歳)に分けた。経過観察期間中、154例が新規に心血管疾患を発症し、86例があらゆる原因で死亡した。Kaplan-Meier分析では低FT3値が新規心血管イベントとあらゆる原因による死亡に対する抗リスクと関連した。FT3と新規心血管疾患イベントの逆相関は、年齢、性別、血液透析期間、糖尿病性腎症、高血圧、脂質異常症、喫煙の補正後も有意であったが、以前の心血管疾患、N末端プロ脳性ナトリウム利尿ペプチドの補正後では有意ではなかった。FT3は総死亡率と独立に関連しなかった。

  • 【糖尿病性腎臓病(DKD)】DKDの治療 糖尿病性腎臓病における脂質管理 Invited Reviewed

    庄司 哲雄

    腎と透析   91 ( 4 )   665 - 671   2021.10( ISSN:0385-2156

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  • Incoherent Optical Tweezers on Black Titanium. Invited Reviewed

    Hashimoto S, Uenobo Y, Takao R, Yuyama KI, Shoji T, Linklater DP, Ivanova E, Juodkazis S, Kameyama T, Torimoto T, Tsuboi Y

    ACS applied materials & interfaces   13 ( 23 )   27586 - 27593   2021.06( ISSN:1944-8244

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    DOI: 10.1021/acsami.1c04929

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  • Association of Zinc Deficiency with Development of CVD Events in Patients with CKD. Invited Reviewed

    Nakatani S, Mori K, Shoji T, Emoto M

    Nutrients   13 ( 5 )   2021.05

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    DOI: 10.3390/nu13051680

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  • Effects of fetuin-A-containing calciprotein particles on posttranslational modifications of fetuin-A in HepG2 cells. Invited Reviewed

    Uedono H, Mori K, Ochi A, Nakatani S, Miki Y, Tsuda A, Morioka T, Nagata Y, Imanishi Y, Shoji T, Inaba M, Emoto M

    Scientific reports   11 ( 1 )   7486   2021.04

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    DOI: 10.1038/s41598-021-86881-0

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  • Difficulty in activities of daily living and falls in patients undergoing hemodialysis: A cross-sectional study with nondialysis controls. Invited Reviewed

    Matsufuji S, Shoji T, Yano Y, Tamaru A, Tsuchikura S, Miyabe M, Kishimoto H, Tsujimoto Y, Emoto M

    Hemodialysis international. International Symposium on Home Hemodialysis   2021.03( ISSN:1492-7535

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    DOI: 10.1111/hdi.12930

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  • Suppression of thyrotropin secretion during roxadustat treatment for renal anemia in a patient undergoing hemodialysis. Reviewed

    Ichii M, Mori K, Miyaoka D, Sonoda M, Tsujimoto Y, Nakatani S, Shoji T, Emoto M

    BMC nephrology   22 ( 1 )   104   2021.03

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    DOI: 10.1186/s12882-021-02304-2

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  • Formation of Single Double-Layered Coacervate of Poly(N,N-diethylacrylamide) in Water by a Laser Tweezer. Invited Reviewed

    Matsumoto M, Asoh TA, Shoji T, Tsuboi Y

    Langmuir : the ACS journal of surfaces and colloids   37 ( 9 )   2874 - 2883   2021.03( ISSN:0743-7463

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    DOI: 10.1021/acs.langmuir.0c03009

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  • Oxidative Stress and Inflammation as Predictors of Mortality and Cardiovascular Events in Hemodialysis Patients: The DREAM Cohort. Invited Reviewed

    Sasaki K, Shoji T, Kabata D, Shintani A, Okute Y, Tsuchikura S, Shimomura N, Tsujimoto Y, Nakatani S, Mori K, Shioi A, Inaba M, Emoto M

    Journal of atherosclerosis and thrombosis   28 ( 3 )   249 - 260   2021.03( ISSN:1340-3478

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    DOI: 10.5551/jat.56069

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  • 血液透析患者の死亡率および心血管イベントの予測因子としての酸化ストレスと炎症 DREAMコホート(Oxidative Stress and Inflammation as Predictors of Mortality and Cardiovascular Events in Hemodialysis Patients: The DREAM Cohort) Invited Reviewed

    Sasaki Keyaki, Shoji Tetsuo, Kabata Daijiro, Shintani Ayumi, Okute Yujiro, Tsuchikura Shoko, Shimomura Naoko, Tsujimoto Yoshihiro, Nakatani Shinya, Mori Katsuhito, Shioi Atsushi, Inaba Masaaki, Emoto Masanori

    Journal of Atherosclerosis and Thrombosis   28 ( 3 )   249 - 260   2021.03( ISSN:1340-3478

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    derivative of reactive oxygen metabolite(d-ROM)から血液透析患者の臨床成績を予測できるかどうか、d-ROMと臨床成績との関連がC反応性蛋白質(CRP)に非依存的かどうかを調べた。血液透析患者から血液検体を採取して、d-ROMアッセイを実施した。総死亡率と新規心血管疾患(CVD)イベントを評価した。血液透析患者517例(男性62.9%、中央値61歳)を解析した。d-ROMはCRPと正に関連した。5年間の経過観察期間中、107例が死亡し、190例が新規CVDイベントを経験した。Kaplan-Meier解析では高d-ROMと高CRPは死亡率とCVDイベントの高リスクを予測した。CRP以外の潜在的交絡因子を補正したコックス比例ハザード回帰分析では、d-ROMsは総死亡率と有意に関連したが、CRPを補正するとこの関連は有意ではなくなった。同じモデルでCRPは総死亡率と有意な関連を示したが、d-ROMsを補正するとこの関連は有意ではなくなった。新規CVDイベントを転帰として分析するとCRPは有意な予測因子であったが、d-ROMは有意な予測因子ではなかった。

  • 【サルコペニア・フレイルの栄養療法・運動療法】CKD存在下のサルコペニア・フレイルの栄養療法・運動療法 サルコペニアとビタミンD Invited Reviewed

    奥手 祐治郎, 庄司 哲雄

    腎と透析   90 ( 3 )   441 - 448   2021.03( ISSN:0385-2156

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  • 腎臓内科学 活性型ビタミンDは透析患者の心血管イベントを抑制するか? Invited Reviewed

    庄司 哲雄

    医歯薬出版(株) 医学のあゆみ   276 ( 7 )   727 - 728   2021.02( ISSN:0039-2359

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  • Laser-Induced Transfer of Noble Metal Nanodots with Femtosecond Laser-Interference Processing. Invited Reviewed

    Nakata Y, Tsubakimoto K, Miyanaga N, Narazaki A, Shoji T, Tsuboi Y

    Nanomaterials (Basel, Switzerland)   11 ( 2 )   2021.01( ISSN:2079-4991

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    DOI: 10.3390/nano11020305

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  • Low Free Triiodothyronine Level as a Predictor of Cardiovascular Events and All-Cause Mortality in Patients Undergoing Hemodialysis: The DREAM Cohort. Invited Reviewed

    Yamazaki Y, Shoji T, Miyashima M, Nagata Y, Kakutani Y, Ochi A, Morioka T, Nakatani S, Mori K, Tsujimoto Y, Emoto M

    Journal of atherosclerosis and thrombosis   2020.12( ISSN:1340-3478

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    DOI: 10.5551/jat.60624

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  • Albuminuria rather than glomerular filtration rate is associated with vascular endothelial function in patients with type 2 diabetes. Invited Reviewed

    Kakutani Y, Morioka T, Mori K, Yamazaki Y, Ochi A, Kurajoh M, Fukumoto S, Shioi A, Shoji T, Inaba M, Emoto M

    Journal of diabetes and its complications   34 ( 12 )   107702   2020.12( ISSN:1056-8727

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    DOI: 10.1016/j.jdiacomp.2020.107702

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  • 【350人に1人 一般内科医が診る人工透析患者】高齢化の進む透析患者への対応 透析患者の認知症 Invited Reviewed

    庄司 哲雄

    (株)診断と治療社 診断と治療   108 ( 11 )   1469 - 1473   2020.11( ISSN:0370-999X

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    <Headline>1 透析患者では、認知症・認知機能低下が高頻度に認められる。2 透析患者では、血管性認知機能障害の機序が多いと想定されている。3 認知症予防とともにQOLの維持改善も重要である。(著者抄録)

  • Visceral adiposity is associated with the discrepancy between glycated albumin and HbA1c in type 2 diabetes. Invited Reviewed

    Maruo S, Motoyama K, Hirota T, Kakutani Y, Yamazaki Y, Morioka T, Mori K, Fukumoto S, Shioi A, Shoji T, Inaba M, Emoto M

    Diabetology international   11 ( 4 )   368 - 375   2020.10( ISSN:2190-1678

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    DOI: 10.1007/s13340-020-00431-z

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  • 【高齢者動脈硬化予防の新展開】動脈硬化性疾患予防のための高齢者CKD管理 Invited Reviewed

    庄司 哲雄

    (株)メディカルレビュー社 Pharma Medica   38 ( 10 )   29 - 33   2020.10( ISSN:0289-5803

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    <文献概要>はじめに 慢性腎臓病(chronic kidney disease:CKD)は心血管疾患(cardiovascular disease:CVD)の高リスク病態であり,リスク低下のためにさまざまな取り組みがなされている。本稿では,CKDにおけるCVDリスク管理について,高齢者を意識して概説を行う。

  • 【評価・処方の"いま"を押さえる 見直し!脂質異常症】(5章)各疾患・ライフステージの心血管イベントリスク・治療の違いを知ろう! 慢性腎臓病を合併した脂質異常症患者をどのように管理しますか? Invited Reviewed

    庄司 哲雄

    (株)日本医事新報社 jmed mook   ( 70 )   160 - 164   2020.10

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    <Point>▼慢性腎臓病(CKD)では、心血管疾患(CVD)のリスクが高い。▼CKDステージが進んだ患者では、動脈硬化性CVD(ASCVD)とともに非動脈硬化性CVD(non-ASCVD)リスクが高まる。▼CKDでは、蛋白尿や腎機能低下に伴いリポ蛋白代謝に異常が認められる。▼CKDでは、多価不飽和脂肪酸プロフィールやコレステロール合成・吸収に変調をきたす。▼CKDステージが進むと、スタチン中心の脂質低下療法で低下できるCVDリスクが小さくなる。▼CKDステージが進むと、CVDリスクにはLDLコレステロール(LDL-C)よりトリグリセライド(TG)の関連がより強く認められる。▼一般診療では、診療ガイドラインや添付文書に沿った治療を心がける。(著者抄録)

  • 【腎疾患コンサルテーション】慢性腎臓病(CKD) CKD患者の動脈硬化はどの程度検索が必要か 保存期、RRT期 Invited Reviewed

    庄司 哲雄

    (株)東京医学社 腎と透析   89 ( 4 )   587 - 590   2020.10( ISSN:0385-2156

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  • 【糖脂質代謝連関と老年病】臨床 透析患者の脂質異常症 Invited Reviewed

    庄司 哲雄

    (株)メディカルレビュー社 The Lipid   31 ( 2 )   154 - 159   2020.10( ISSN:0915-6607

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    血液透析患者は慢性腎臓病の最も進んだステージにあり、心血管疾患(CVD)死亡のリスクが非常に高い。その危険因子として脂質異常症が想定されてきたが、進んだステージのCKDほどLDL-C値とCVDリスクの関連は乏しいことが示されている。脂質関連の危険因子としては変成リポ蛋白、コレステロール合成・吸収マーカー、脂肪酸プロフィールなどの関連が示されている。(著者抄録)

  • 【動脈硬化進行予防のための肥満・脂質異常診療戦略】動脈硬化予防のための肥満・脂質異常の治療 スタチンとエゼチミブ Invited Reviewed

    宮島 雅子, 庄司 哲雄

    (株)診断と治療社 診断と治療   108 ( 10 )   1363 - 1367   2020.10( ISSN:0370-999X

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    <Headline>1 動脈硬化性疾患の予防においては、患者の絶対リスクを評価し、保有するリスクファクタープロフィールを考慮して、包括的リスク管理を行うことが推奨されている。2 スタチンは、コレステロール合成経路の律速酵素であるHMG-CoA還元酵素の阻害薬であり、高LDL-C血症に対する第一選択薬と位置づけられている。様々な臨床研究でスタチンによるCVDリスク低下が繰り返し確認されている。3 エゼチミブは、小腸で発現しコレステロールの吸収を司っているトランスポーター蛋白であるNPC1L1に結合することで、小腸からのコレステロール吸収を阻害する。スタチンと併用することで、さらなるLDL-C低下が可能であり、CVDイベント発症リスクをさらに低下できるとの介入研究が報告されている。(著者抄録)

  • 2型糖尿病において内臓脂肪はグリコアルブミンとHbA1cの乖離に関連する(Visceral adiposity is associated with the discrepancy between glycated albumin and HbA1c in type 2 diabetes) Invited Reviewed

    Maruo Saori, Motoyama Koka, Hirota Tomoe, Kakutani Yoshinori, Yamazaki Yuko, Morioka Tomoaki, Mori Katsuhito, Fukumoto Shinya, Shioi Atsushi, Shoji Tetsuo, Inaba Masaaki, Emoto Masanori

    Diabetology International   11 ( 4 )   368 - 375   2020.10( ISSN:2190-1678

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    2型糖尿病患者123例(男性68例、女性55例、平均61.3±13.7歳)を対象として、2型糖尿病患者における内臓脂肪面積(VFA)とグリコアルブミン(GA)およびGA/HbA1cとの関連性について横断的に検討した。VFAはデュアルインピーダンス法、GAおよびHbA1cは酵素法により測定した。単回帰分析により、BMIはGA、GA/HbA1cと有意な負の関連が認められたが、HbA1cと有意な関連は認められなかった。VFAはGAおよびGA/HbA1cと有意な負の関連を示した。また、重回帰分析にてVFAがGA/HbA1cの独立した寄与因子であった。GAは血糖コントロールの有用な指標であるが、2型糖尿病においては内臓脂肪の影響も考慮する必要性が示唆された。

  • Better remission rates in elderly Japanese patients with primary membranous nephropathy in nationwide real-world practice: The Japan Nephrotic Syndrome Cohort Study (JNSCS). Invited Reviewed

    Yokoyama H, Yamamoto R, Imai E, Maruyama S, Sugiyama H, Nitta K, Tsukamoto T, Uchida S, Takeda A, Sato T, Wada T, Hayashi H, Akai Y, Fukunaga M, Tsuruya K, Masutani K, Konta T, Shoji T, Hiramatsu T, Goto S, Tamai H, Nishio S, Shirasaki A, Nagai K, Yamagata K, Hasegawa H, Yasuda H, Ichida S, Naruse T, Fukami K, Nishino T, Sobajima H, Tanaka S, Akahori T, Ito T, Terada Y, Katafuchi R, Fujimoto S, Okada H, Ishimura E, Kazama JJ, Hiromura K, Mimura T, Suzuki S, Saka Y, Sofue T, Suzuki Y, Shibagaki Y, Kitagawa K, Morozumi K, Fujita Y, Mizutani M, Shigematsu T, Furuichi K, Fujimoto K, Kashihara N, Sato H, Matsuo S, Narita I, Isaka Y

    Clinical and experimental nephrology   24 ( 10 )   893 - 909   2020.10( ISSN:1342-1751

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    DOI: 10.1007/s10157-020-01913-9

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  • Microanalysis of Single Poly(N-isopropylacrylamide) Droplet Produced by an Optical Tweezer in Water: Isotacticity Dependence of Growth and Chemical Structure of the Droplet. Invited Reviewed

    Ushiro K, Shoji T, Matsumoto M, Asoh TA, Horibe H, Katsumoto Y, Tsuboi Y

    The journal of physical chemistry. B   124 ( 38 )   8454 - 8463   2020.09

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    DOI: 10.1021/acs.jpcb.0c06932

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  • Association between Serum Zinc and Calcification Propensity (T<sub>50</sub>) in Patients with Type 2 Diabetes Mellitus and In Vitro Effect of Exogenous Zinc on T<sub>50</sub>. Invited Reviewed

    Nakatani S, Mori K, Sonoda M, Nishide K, Uedono H, Tsuda A, Emoto M, Shoji T

    Biomedicines   8 ( 9 )   2020.09

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    DOI: 10.3390/biomedicines8090337

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  • 【腎臓と他臓器連関を考える-CKDにおける包括的治療戦略を目指して】臓器連関の実態 心腎連関 血管の観点から Invited Reviewed

    庄司 哲雄

    (株)南江堂 内科   126 ( 2 )   185 - 188   2020.08( ISSN:0022-1961

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    <文献概要>▼慢性腎臓病は心血管疾患の高リスク病態であり,「心腎連関」として知られている.▼その中心となる血管障害は,動脈の壁肥厚,内腔狭窄,壁硬化,血管石灰化として捉えることができる.▼ランダム化比較試験(RCT)の結果からは,厳格な血圧管理や脂質管理による腎予後の改善は示されていない.

  • 糖尿病における上腕血圧左右差およびその末梢動脈疾患との選択的関連(Inter-Arm Blood Pressure Difference in Diabetes Mellitus and Its Preferential Association with Peripheral Artery Disease) Invited Reviewed

    Miyashima Masako, Shoji Tetsuo, Kakutani Yoshinori, Yamazaki Yuko, Ochi Akinobu, Morioka Tomoaki, Shinohara-Mitsuki Kayo, Fukumoto Shinya, Shioi Atsushi, Inaba Masaaki, Emoto Masanori

    (一社)日本動脈硬化学会 Journal of Atherosclerosis and Thrombosis   27 ( 8 )   780 - 788   2020.08( ISSN:1340-3478

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    自動血圧測定器を用いて両上腕血圧を測定した被験者を、糖尿病患者1316例と非糖尿病患者1264例に分類し、上腕血圧の左右差(IAD)に対する糖尿病の関与と、心血管疾患との関連を横断研究により検討した。糖尿病患者は非糖尿病患者と比べてIADの値が大きく、10mmHg以上のIADの有病率が有意に高かったが、交絡因子を補正後に有意差はなくなった。心血管疾患のリスク因子で補正後のモデルにおいて、冠動脈疾患、脳卒中、末梢動脈疾患のうち、末梢動脈疾患のみがIADと有意に関連した。特に若年の患者では、末梢動脈疾患とIADの相関が顕著であった。糖尿病はIADの独立関連因子ではなかった。

  • 【症例で学ぶ!腎泌尿器診療ガイドラインの使い方】(第8章)代謝性疾患 脂質異常症 Invited Reviewed

    庄司 哲雄

    (株)東京医学社 腎と透析   88 ( 増刊 )   384 - 389   2020.06( ISSN:0385-2156

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  • 【透析患者の脳血管障害】脳血管障害の危険因子とその管理 脂質異常症 Invited Reviewed

    庄司 哲雄

    (株)日本メディカルセンター 臨床透析   36 ( 6 )   561 - 566   2020.06( ISSN:0910-5808

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    <文献概要>脳卒中は出血性と虚血性に区別され,病態が異なる.脂質異常症と関連するのは脳梗塞で,血液透析患者でも総コレステロール,トリグリセライド,non-HDL-C高値でオッズが高い.一方,脳出血はトリグリセライド低値でオッズが高い.脂質低下療法を実施して血液透析患者の脳卒中リスクが抑制できるかについては,エビデンスが乏しい.

  • Electrophoretic Adhesion of Conductive Hydrogels. Invited Reviewed

    Asoh TA, Nakamura M, Shoji T, Tsuboi Y, Uyama H

    Macromolecular rapid communications   41 ( 12 )   e2000169   2020.06( ISSN:1022-1336

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    DOI: 10.1002/marc.202000169

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  • Incidence of remission and relapse of proteinuria, end-stage kidney disease, mortality, and major outcomes in primary nephrotic syndrome: the Japan Nephrotic Syndrome Cohort Study (JNSCS). Invited Reviewed

    Yamamoto R, Imai E, Maruyama S, Yokoyama H, Sugiyama H, Nitta K, Tsukamoto T, Uchida S, Takeda A, Sato T, Wada T, Hayashi H, Akai Y, Fukunaga M, Tsuruya K, Masutani K, Konta T, Shoji T, Hiramatsu T, Goto S, Tamai H, Nishio S, Shirasaki A, Nagai K, Yamagata K, Hasegawa H, Yasuda H, Ichida S, Naruse T, Nishino T, Sobajima H, Tanaka S, Akahori T, Ito T, Terada Y, Katafuchi R, Fujimoto S, Okada H, Ishimura E, Kazama JJ, Hiromura K, Mimura T, Suzuki S, Saka Y, Sofue T, Suzuki Y, Shibagaki Y, Kitagawa K, Morozumi K, Fujita Y, Mizutani M, Shigematsu T, Kashihara N, Sato H, Matsuo S, Narita I, Isaka Y

    Clinical and experimental nephrology   24 ( 6 )   526 - 540   2020.06( ISSN:1342-1751

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    DOI: 10.1007/s10157-020-01864-1

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  • Reference Intervals of Serum Non-Cholesterol Sterols by Gender in Healthy Japanese Individuals. Invited Reviewed

    Yoshida H, Tada H, Ito K, Kishimoto Y, Yanai H, Okamura T, Ikewaki K, Inagaki K, Shoji T, Bujo H, Miida T, Yoshida M, Kuzuya M, Yamashita S

    Journal of atherosclerosis and thrombosis   27 ( 5 )   409 - 417   2020.05( ISSN:1340-3478

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    DOI: 10.5551/jat.50187

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  • J-DAVID試験で目指したことと得られたこと Invited Reviewed

    庄司 哲雄

    (有)科学評論社 腎臓内科   11 ( 5 )   571 - 575   2020.05( ISSN:2435-1903

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  • 健康な日本人における血清非コレステロールステロールの男女別基準値(Reference Intervals of Serum Non-Cholesterol Sterols by Gender in Healthy Japanese Individuals) Invited Reviewed

    Yoshida Hiroshi, Tada Hayato, Ito Kumie, Kishimoto Yoshimi, Yanai Hidekatsu, Okamura Tomonori, Ikewaki Katsunori, Inagaki Kyoko, Shoji Tetsuo, Bujo Hideaki, Miida Takashi, Yoshida Masayuki, Kuzuya Masafumi, Yamashita Shizuya

    (一社)日本動脈硬化学会 Journal of Atherosclerosis and Thrombosis   27 ( 5 )   409 - 417   2020.05( ISSN:1340-3478

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    血清中の非コレステロールステロール濃度とその基準範囲を測定するための手法について検討した。健常者260名(男性109名;平均35.8±10.7歳、女性151名;平均35.9±11.0歳)とシトステロール血症患者14例を対象とした。シトステロール血症患者はABCG5/ABCG8遺伝子の二重病因性突然変異を有する女性患者4例(平均9.5±8.2歳)とABCG5/ABCG8遺伝子のヘテロ接合性突然変異を保有10例(男性4例、平均41.5±25.5歳、女性6例、平均47.5±13.8歳)であった。シトステロール、カンプエステロール、ラソステロールの空腹時血清中濃度を実用的および高感度ガスクロマトグラフィーで、定量の下限値0.2μg/mLで測定した。シトステロール、カンプエステロールは男性よりも女性で有意に高く、ラソステロールは女性よりも男性で有意に高かった。シトステロール、カンプエステロール、ラソステロールの基準範囲は男性では0.99〜3.88μg/mL、2.14〜7.43μg/mL、0.77〜3.60μg/mL、女性では1.03〜4.45μg/mL、2.19〜8.34μg/mL、0.64〜2.78μg/mLであった。シトステロール、カンプエステロールの血清中濃度はシトステロール血症患者が94.3±47.3μg/mLで、健常者(66.3±36.6μg/mL)よりも高かった。

  • 【CKD-MBD】Ca受容体作動薬と活性型VD製剤の選択と併用 Invited Reviewed

    仲谷 慎也, 上殿 英記, 森 克仁, 庄司 哲雄

    (有)科学評論社 腎臓内科   11 ( 5 )   518 - 526   2020.05( ISSN:2435-1903

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  • 心腎連関(Series No.3) 慢性腎臓病の心血管疾患と脂質異常症 Invited Reviewed

    庄司 哲雄, 中舎 璃乃

    (株)学樹書院 臨床医のための循環器診療   ( 32 )   34 - 36   2020.03( ISSN:1348-2351

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  • Plasmonic Manipulation of DNA using a Combination of Optical and Thermophoretic Forces: Separation of Different-Sized DNA from Mixture Solution. Invited Reviewed

    Shoji T, Itoh K, Saitoh J, Kitamura N, Yoshii T, Murakoshi K, Yamada Y, Yokoyama T, Ishihara H, Tsuboi Y

    Scientific reports   10 ( 1 )   3349   2020.02

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    DOI: 10.1038/s41598-020-60165-5

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  • The Inhibitory Roles of Vitamin K in Progression of Vascular Calcification. Reviewed

    Shioi A, Morioka T, Shoji T, Emoto M

    Nutrients   12 ( 2 )   2020.02

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    DOI: 10.3390/nu12020583

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  • Inter-Arm Blood Pressure Difference in Diabetes Mellitus and Its Preferential Association with Peripheral Artery Disease. Reviewed

    Miyashima M, Shoji T, Kakutani Y, Yamazaki Y, Ochi A, Morioka T, Shinohara-Mitsuki K, Fukumoto S, Shioi A, Inaba M, Emoto M

    Journal of atherosclerosis and thrombosis   2019.12( ISSN:1340-3478

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    DOI: 10.5551/jat.52886

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  • Plasma omentin levels are inversely associated with atherosclerosis in type 2 diabetes patients with increased plasma adiponectin levels: a cross-sectional study. Reviewed

    Nishimura M, Morioka T, Hayashi M, Kakutani Y, Yamazaki Y, Kurajoh M, Mori K, Fukumoto S, Shioi A, Shoji T, Inaba M, Emoto M

    Cardiovascular diabetology   18 ( 1 )   167   2019.12

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    DOI: 10.1186/s12933-019-0973-3

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  • リポ蛋白だけでは語れないCKDの脂質異常とCVD Invited Reviewed

    庄司 哲雄

    (一社)大阪府内科医会 大阪府内科医会会誌   28 ( 2 )   136 - 140   2019.12( ISSN:1881-669X

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    慢性腎臓病では、蛋白尿、腎機能、基礎疾患として糖尿病を有するかどうかでリポ蛋白の代謝の変化が理解できる。また、腎機能(eGFR)が低い患者ほどコレステロール合成マーカーが低値でコレステロール吸収マーカーが高値になることから、肝臓での合成が低下し小腸からの吸収が高まると考えられている。その背後に、慢性腎機能低下に伴うPPARα不全が想定されている。コレステロール吸収の亢進は総死亡高リスクの予測因子であり、スタチンによるCVDイベント抑制の効果修飾因子でもある。(著者抄録)

  • アデノシンはアデノシンA3受容体を介して大動脈平滑筋細胞の石灰化を減弱する(Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A3 Adenosine Receptor) Invited Reviewed

    Fujimoto Kenta, Shioi Atsushi, Miki Yuya, Kakutani Yoshinori, Morioka Tomoaki, Shoji Tetsuo, Emoto Masanori, Inaba Masaaki

    東北ジャーナル刊行会 The Tohoku Journal of Experimental Medicine   249 ( 4 )   275 - 283   2019.12( ISSN:0040-8727

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    ヒト大動脈血管平滑筋細胞(HASMC)石灰化に対するアデノシンシグナル伝達の抑制作用を調べた。HASMCをオンコスタチンM(OSM)と骨形成分化培地(ODM)で処理することにより、骨芽細胞分化とマトリックス石灰化をさせた血管石灰化in vitroモデルを利用した。検討の結果、アデノシンはALP活性と組織非特異的アルカリホスファターゼ(TNAP)mRNAの発現を大幅に抑制した。代謝的に安定した類似体である2-クロロアデノシン(CADO)は、TNAPのmRNA発現を有意に抑制したが、Runt関連転写因子2(RUNX2)および骨シアロタンパク質(BSP)-IIのmRNA発現は抑制しなかった。CCPA(A1 AR選択的アゴニスト)、CGS21680(A2a AR選択的アゴニスト)、BAY60-6583(A2b AR選択的アゴニスト)はHASMC石灰化とALP活性を阻害しなかったのに対し、IB-MECA(A3 AR-選択的アゴニスト)はin vitroの石灰化とALP活性の両方を用量依存的に減少させた。さらに、IB-MECAはTNAPのmRNA発現も有意に抑制したが、RUNX2およびBSP-IIのmRNA発現は抑制しなかった。また、A3 ARをノックダウンすると、HASMCの石灰化およびALP活性におけるアデノシン、CADO、IB-MECAの阻害作用が大幅に遮断された。以上のデータから、A3 AR活性化がHASMC石灰化に対するアデノシンシグナル伝達の抑制作用を媒介することが示唆された。

  • CKD-MBD治療 何が確かで何が不確かなのか Invited Reviewed

    庄司 哲雄

    (公社)日本透析医会 日本透析医会雑誌   34 ( 3 )   509 - 511   2019.12( ISSN:0914-7136

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  • Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A<sub>3</sub> Adenosine Receptor. Reviewed

    Fujimoto K, Shioi A, Miki Y, Kakutani Y, Morioka T, Shoji T, Emoto M, Inaba M

    The Tohoku journal of experimental medicine   249 ( 4 )   275 - 283   2019.12( ISSN:0040-8727

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    DOI: 10.1620/tjem.249.275

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  • 【動脈硬化診療のすべて】(II章)動脈硬化を識る 危険因子・関連疾患とその予防・治療 慢性腎臓病 Invited Reviewed

    庄司 哲雄

    (公社)日本医師会 日本医師会雑誌   148 ( 特別2 )   S116 - S119   2019.10( ISSN:0021-4493

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  • Oncostatin M induces C2C12 myotube atrophy by modulating muscle differentiation and degradation. Invited Reviewed

    Miki Y, Morioka T, Shioi A, Fujimoto K, Sakura T, Uedono H, Kakutani Y, Ochi A, Mori K, Shoji T, Emoto M, Inaba M

    Biochemical and biophysical research communications   516 ( 3 )   951 - 956   2019.08( ISSN:0006-291X

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    DOI: 10.1016/j.bbrc.2019.06.143

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  • 【透析患者における認知症】透析患者の認知症の疫学 Invited Reviewed

    佐々木 けやき, 庄司 哲雄

    扶桑薬品工業(株) 透析フロンティア   29 ( 3 )   2 - 6   2019.08( ISSN:0917-2114

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  • 【脂質異常症 基礎と臨床UPDATE-食事療法を正しく理解するために】CKD・透析患者における脂質異常 Invited Reviewed

    庄司 哲雄

    臨床栄養   135 ( 1 )   45 - 50   2019.07( ISSN:0485-1412

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  • 【全身性疾患と腎update】(第2章)代謝性疾患 脂質代謝障害・循環器専門医の視点より Invited Reviewed

    庄司 哲雄

    腎と透析   86 ( 増刊 )   163 - 165   2019.06( ISSN:0385-2156

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  • 脳心血管病予防に関する包括的リスク管理チャート2019年版について Invited Reviewed

    寺本 民生, 荒井 秀典, 磯 博康, 野出 孝一, 松本 昌泰, 飯田 真美, 小熊 祐子, 井上 茂, 永富 良一, 庄司 哲雄, 楽木 宏実, 曽根 博仁, 宮崎 滋, 神崎 恒一, 脳心血管病協議会, 一般社団法人日本疫学会, 特定非営利活動法人日本高血圧学会, 一般社団法人日本循環器学会, 一般社団法人日本腎臓学会, 一般社団法人日本総合健診医学会, 一般社団法人日本体力医学会, 一般社団法人日本痛風・核酸代謝学会, 一般社団法人日本糖尿病学会, 一般社団法人日本動脈硬化学会, 一般社団法人日本内科学会, 一般社団法人日本脳卒中学会, 一般社団法人日本肥満学会, 一般社団法人日本老年医学会, 一般社団法人日本神経学会, 一般社団法人日本医学会連合, 公益社団法人日本医師会

    日本内科学会雑誌   108 ( 5 )   1024 - 1074   2019.05( ISSN:0021-5384

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  • 【ナゾ解き生化学おもしろ講座 イラストでわかる5大栄養素のはたらき】脂質のはたらき Invited Reviewed

    庄司 哲雄

    Nutrition Care   12 ( 4 )   342 - 346   2019.04( ISSN:1882-3343

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  • Impact of diabetes on sarcopenia and mortality in patients undergoing hemodialysis. Invited Reviewed

    Mori K, Nishide K, Okuno S, Shoji T, Emoto M, Tsuda A, Nakatani S, Imanishi Y, Ishimura E, Yamakawa T, Shoji S, Inaba M

    BMC nephrology   20 ( 1 )   105   2019.03

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    DOI: 10.1186/s12882-019-1271-8

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  • JNK and ATF4 as two important platforms for tumor necrosis factor-α-stimulated shedding of receptor for advanced glycation end products. Invited Reviewed

    Miyoshi A, Koyama S, Sasagawa-Monden M, Kadoya M, Konishi K, Shoji T, Inaba M, Yamamoto Y, Koyama H

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology   33 ( 3 )   3575 - 3589   2019.03( ISSN:0892-6638

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    DOI: 10.1096/fj.201701553RR

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  • Steno-Stiffness Approach for Cardiovascular Disease Risk Assessment in Primary Prevention. Invited Reviewed

    Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A, Collaborative Group for J-BAVELs (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies)

    Hypertension (Dallas, Tex. : 1979)   73 ( 3 )   508 - 513   2019.03( ISSN:0194-911X

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    DOI: 10.1161/HYPERTENSIONAHA.118.12110

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  • Plasma omentin levels are associated with vascular endothelial function in patients with type 2 diabetes at elevated cardiovascular risk. Invited Reviewed

    Hayashi M, Morioka T, Hatamori M, Kakutani Y, Yamazaki Y, Kurajoh M, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Emoto M, Inaba M

    Diabetes research and clinical practice   148   160 - 168   2019.02( ISSN:0168-8227

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    DOI: 10.1016/j.diabres.2019.01.009

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  • 【スタチンを使いこなす!18のクリニカル・パールズ】スタチンを誰にどのように使うのか? 慢性腎臓病(CKD)患者に対するスタチン処方にはどんなメリット・注意点がありますか? Invited Reviewed

    庄司 哲雄

    Modern Physician   39 ( 2 )   182 - 185   2019.02( ISSN:0913-7963

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    <ポイント>●軽度〜中等度CKDではスタチンによる心血管イベントの相対リスク低下が大きい。●eGFRが低いほどスタチンによる心血管イベントの相対リスク低下が小さくなる。●透析患者に新たにスタチン単独、あるいはスタチン・エゼチミブ併用を開始することは推奨されていない。●スタチンによる腎保護効果について、現時点では十分なエビデンスはない。●CKDでスタチンを用いる場合、薬物相互作用に注意する。(著者抄録)

  • 【慢性腎臓病における心血管障害】総論 CKDにおけるCVDの疫学と病態 動脈硬化の病態総論 Invited Reviewed

    庄司 哲雄

    腎と透析   86 ( 1 )   11 - 15   2019.01( ISSN:0385-2156

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  • 【腎と栄養・代謝】腎と脂質 Invited Reviewed

    庄司 哲雄

    腎臓内科・泌尿器科   9 ( 1 )   22 - 26   2019.01( ISSN:2188-9147

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  • 【脂質異常症 新たな時代に入った脂質異常症治療をふまえて】日常診療に必要な具体的知識とその活用 CKDと脂質異常症 成因と治療 Invited Reviewed

    庄司 哲雄

    Medical Practice   36 ( 1 )   85 - 90   2019.01( ISSN:0910-1551

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  • Regional variations in immunosuppressive therapy in patients with primary nephrotic syndrome: the Japan nephrotic syndrome cohort study. Invited Reviewed

    Yamamoto R, Imai E, Maruyama S, Yokoyama H, Sugiyama H, Nitta K, Tsukamoto T, Uchida S, Takeda A, Sato T, Wada T, Hayashi H, Akai Y, Fukunaga M, Tsuruya K, Masutani K, Konta T, Shoji T, Hiramatsu T, Goto S, Tamai H, Nishio S, Shirasaki A, Nagai K, Yamagata K, Hasegawa H, Yasuda H, Ichida S, Naruse T, Fukami K, Nishino T, Sobajima H, Tanaka S, Akahori T, Ito T, Yoshio T, Katafuchi R, Fujimoto S, Okada H, Ishimura E, Kazama JJ, Hiromura K, Mimura T, Suzuki S, Saka Y, Sofue T, Suzuki Y, Shibagaki Y, Kitagawa K, Morozumi K, Fujita Y, Mizutani M, Shigematsu T, Kashihara N, Sato H, Matsuo S, Narita I, Isaka Y

    Clinical and experimental nephrology   22 ( 6 )   1266 - 1280   2018.12( ISSN:1342-1751

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    DOI: 10.1007/s10157-018-1579-x

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  • Laser trapping/confocal Raman spectroscopic characterization of PLGA-PEG nanoparticles. Invited Reviewed

    Yang J, Zhang RN, Liu DJ, Zhou X, Shoji T, Tsuboi Y, Yan H

    Soft matter   14 ( 40 )   8090 - 8094   2018.10( ISSN:1744-683X

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    DOI: 10.1039/c8sm01364k

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  • 【CKD-MBDのリン管理 栄養・薬物療法の実践力を身につける】リン吸着薬・カルシウム受容体作動薬・ビタミンD製剤を使いこなす!プロが教える"知識"と"ノウハウ" 活性型ビタミンD製剤 Invited Reviewed

    庄司 哲雄

    薬局   69 ( 11 )   3186 - 3189   2018.10( ISSN:0044-0035

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    <Key Points>◎活性型ビタミンD製剤(VDRA)は二次性副甲状腺機能亢進症、低カルシウム血症の治療に用いる。◎投与開始や用量調整の目安は、診療ガイドラインや添付文書を参考にする。◎血清リン、Ca値は月2回、VDRA投与中のintact PTH値は月1回程度モニターする。◎検査結果はそのトレンドをみて、治療の変更を判断する。◎VDRA投与で心血管アウトカムが改善するというランダム化比較試験によるエビデンスはない。(著者抄録)

  • Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017. Invited Reviewed

    Kinoshita M, Yokote K, Arai H, Iida M, Ishigaki Y, Ishibashi S, Umemoto S, Egusa G, Ohmura H, Okamura T, Kihara S, Koba S, Saito I, Shoji T, Daida H, Tsukamoto K, Deguchi J, Dohi S, Dobashi K, Hamaguchi H, Hara M, Hiro T, Biro S, Fujioka Y, Maruyama C, Miyamoto Y, Murakami Y, Yokode M, Yoshida H, Rakugi H, Wakatsuki A, Yamashita S, Committee for Epidemiology and Clinical Management of Atherosclerosis

    Journal of atherosclerosis and thrombosis   25 ( 9 )   846 - 984   2018.09( ISSN:1340-3478

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    DOI: 10.5551/jat.GL2017

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  • 肥満2型糖尿病患者における血漿レプチン値と睡眠の質との正の関連(Positive association of plasma leptin with sleep quality in obese type 2 diabetes patients) Invited Reviewed

    Hirota Tomoe, Morioka Tomoaki, Yoda Koichiro, Toi Norikazu, Hayashi Noriyuki, Maruo Saori, Yamazaki Yuko, Kurajoh Masafumi, Motoyama Koka, Yamada Shinsuke, Shoji Tetsuo, Emoto Masanori, Inaba Masaaki

    Journal of Diabetes Investigation   9 ( 5 )   1100 - 1105   2018.09( ISSN:2040-1116

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    2型糖尿病患者におけるレプチンと睡眠の質との関連を調べた。2011年10月〜2016年7月に当施設に入院した2型糖尿病患者182例(男性100例、女性82例、年齢中央値61歳)を対象に、空腹時血漿レプチン値を測定し、単一チャネル脳波で睡眠構造を評価した。最初の睡眠周期中のデルタパワーを用いて解析した。肥満群は113例、非肥満群は69例であった。未調整解析では肥満群で血漿レプチン値とデルタパワーで評価した熟睡に対するパラメータとの間に正の関連があった。年齢、BMI、無呼吸低呼吸指数といった潜在的交絡因子の補正後、多変量解析では肥満群で血漿レプチン値はデルタパワーと正の関連を示したが、総睡眠時間とは関連しなかった。非肥満群ではデルタパワーも総睡眠時間もレプチン値とは関連しなかった。

  • 日本動脈硬化学会(JAS) アテローム性動脈硬化性疾患予防ガイドライン2017(Japan Atherosclerosis Society(JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017) Invited Reviewed

    Kinoshita Makoto, Yokote Koutaro, Arai Hidenori, Iida Mami, Ishigaki Yasushi, Ishibashi Shun, Umemoto Seiji, Egusa Genshi, Ohmura Hirotoshi, Okamura Tomonori, Kihara Shinji, Koba Shinji, Saito Isao, Shoji Tetsuo, Daida Hiroyuki, Tsukamoto Kazuhisa, Deguchi Juno, Dohi Seitaro, Dobashi Kazushige, Hamaguchi Hirotoshi, Hara Masumi, Hiro Takafumi, Biro Sadatoshi, Fujioka Yoshio, Maruyama Chizuko, Miyamoto Yoshihiro, Murakami Yoshitaka, Yokode Masayuki, Yoshida Hiroshi, Rakugi Hiromi, Wakatsuki Akihiko, Yamashita Shizuya, Ninomiya Toshiharu, Hozawa Atsushi, Hasegawa Koji, Yamato Hiroshi, Abe Takaaki, Emoto Masanori, Kashihara Naoki, Saiki Atsuhito, Tomiyama Hirofumi, Hashimoto Jun-ichiro, Hosomi Naohisa, Yamazaki Yoshimitsu, Bujo Hideaki, Inoue Ikuo, Inoue Shigeru, Sawada Susumu, Sone Hirohito, Hiro Sadatoshi, Funabashi Tohru, Matsumoto Masayasu, Ohtsuki Toshiho, Kitagawa Kazuo, Kitazono Takanari, Terayama Yasuo, Tomimoto Hidekazu, Toyoda Kazunori, Harada-Shiba Mariko, Nohara Atsushi, Ohta Takao, Ogura Masatsune, Ohtake Akira, Inagaki Kyoko, Ohira Hideo, Okazaki Hiroaki, Okamoto Yoshihisa, Kanamori Kenta, Kameyama Noriko, Kurano Makoto, Komamura Kazuo, Satoi Keiko, Sato Kayoko, Shigeshiro Kentaro, Sugiyama Daisuke, Suzuki Reiko, Sekiguchi Haruki, Takase Satoru, Takanashi Mikio, Takegami Misa, Tamura Yukinori, Tsutsui Wao, Hyakutake Aiko, Hirata Aya, Hirayama Satoshi, Fukushima Yoshifumi, Miida Takashi, Yamada Yoko, Watanabe Takuya, Tsuchihashi Takuya, Momomura Shin-ichi, Yoshizumi Tohru, Kuzuya Masafumi, Kozaki Koichi, Masuzaki Hiroaki, Masuda Daisaku, Morizane Toshio, Noto Hiroshi, Iso Hiroyasu, Node Koichi, Hirata Kenichi, Okada Koichi, Fukutake Katsuyuki, Nagatomi Ryoichi, Miyamoto Susumu, Kasuga Masato, Shirai Kohji, Furukawa Taiji, Akishita Masahiro, Committee for Epidemiology and Clinical Management of Atherosclerosis

    Journal of Atherosclerosis and Thrombosis   25 ( 9 )   846 - 984   2018.09( ISSN:1340-3478

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  • Positive association of plasma leptin with sleep quality in obese type 2 diabetes patients. Invited Reviewed

    Hirota T, Morioka T, Yoda K, Toi N, Hayashi N, Maruo S, Yamazaki Y, Kurajoh M, Motoyama K, Yamada S, Shoji T, Emoto M, Inaba M

    Journal of diabetes investigation   9 ( 5 )   1100 - 1105   2018.09( ISSN:2040-1116

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    DOI: 10.1111/jdi.12826

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  • 腹腔内遊離ガスや門脈ガス血症を伴う腸管気腫症を合併した血液透析患者の2症例 Invited Reviewed

    下村 菜生子, 田畑 勉, 森本 章, 岩田 愛, 細見 由佳, 藤原 木綿子, 岸本 博至, 西澤 良記, 辻本 吉広, 庄司 哲雄, 絵本 正憲, 稲葉 雅章

    日本透析医学会雑誌   51 ( 8 )   509 - 515   2018.08( ISSN:1340-3451

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    血液透析患者に腹腔内遊離ガスや門脈ガス血症を伴った腸管気腫症を合併した2症例を経験したので報告する。症例1は65歳、女性。8年間の腹膜透析後に、血液透析に移行した。被嚢性腹膜硬化症の前期が疑われ、プレドニゾロンが開始された。ステロイドによる血糖上昇に対し処方されたα-グルコシダーゼ阻害薬(α-glucosidase inhibitor:α-GI)服用後、腹満感が出現した。腹部CTにて遊離ガス像を伴う腸管気腫症と診断され、原因薬剤であるα-GIの中止にて改善をみた。症例2は76歳、女性。62歳時に血液透析導入、75歳時に出血性直腸潰瘍の既往あり。腹痛、嘔吐出現、腹部CTで門脈内ガスと腸管気腫像がみられた。断食と抗菌薬治療にて、症状は軽快しCTにおける門脈内ガス、腸管気腫像は消失した。消化管穿孔や腸管壊死を除外できれば、遊離ガスや門脈内ガスを伴っていても腸管気腫症に対しては、保存的治療が選択肢の一つである。(著者抄録)

  • 紅麹のLDL-C低下効果 境界域高LDL-C血症の健常人を含むランダム化比較試験の層別解析 Invited Reviewed

    庄司 哲雄, 福井 充, 藤井 比佐子

    アンチ・エイジング医学   14 ( 4 )   533 - 541   2018.08( ISSN:1880-1579

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    【目的】健常人における紅麹の低比重リポ蛋白コレステロール(LDL-C)低下効果をLDL-C前値別に検討した。【方法】本研究は、健常人を対象に、8週間のプラセボ、紅麹100mg、紅麹200mgの摂取によるLDL-C低下作用を検証した二重盲検ランダム化比較試験の事後解析である。LDL-C前値により層A(120〜139mg/dL、境界域高LDL-C血症、n=21)、層B(140〜159mg/dL、n=22)、層C(≧160mg/dL、n=21)に層別した。摂食後のLDL-C値(主要評価項目)を試験食3群間で比較した(分散分析)。また、LDL-C変化量(副次評価項目)も比較した(摂食前LDL-C値、年齢、性別で調整した共分散分析)。【結果】摂取後のLDL-C値(単位mg/dL)は、層Aのプラセボ群、紅麹100mg群、紅麹200mg群の順に、137±20、114±11、108±14であり、有意差が認められた(p=0.008)。LDL-C変化量(mg/dL)は、+5±21、-16±8、-20±15で有意差が認められた(p=0.035)。層Bでも試験食3群間でLDL-C値に有意差が認められたが、層Cでは有意ではなかった。これらの結果は、高トリグリセライド血症症例を除外した場合も、LDL-C変化量の解析でも同様であった。【結論】紅麹100mg、200mgの摂取によるLDL-C低下効果は、LDL-C前値が120〜139mg/dL(境界域高LDL-C血症)の健常人および140〜159mg/dLの群において有意であった。(著者抄録)

  • 【放っておくとこわいCKD-MBD 透析患者のリン・カルシウム代謝異常】リン・カルシウム代謝異常を理解するための予備知識 ホルモン 活性型ビタミンD Invited Reviewed

    辻本 吉広, 庄司 哲雄

    透析ケア   24 ( 8 )   694 - 695   2018.08( ISSN:1341-1489

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  • 【放っておくとこわいCKD-MBD 透析患者のリン・カルシウム代謝異常】リン・カルシウム代謝異常のプロセス ビタミンD活性化障害 Invited Reviewed

    辻本 吉広, 庄司 哲雄

    透析ケア   24 ( 8 )   708 - 709   2018.08( ISSN:1341-1489

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  • 【動脈硬化予防のための脂質異常症治療最前線】高リスク病態に対する積極的脂質低下と管理目標 Invited Reviewed

    庄司 哲雄

    日本医師会雑誌   147 ( 5 )   986 - 986   2018.08( ISSN:0021-4493

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  • Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: An individual participant data meta-analysis. Invited Reviewed

    Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A, collaborative group for the Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies to examine the significance of the Ankle-Brachial Index (J-BAVEL-ABI)

    Atherosclerosis   275   141 - 148   2018.08( ISSN:0021-9150

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    DOI: 10.1016/j.atherosclerosis.2018.05.048

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  • Plasma polyunsaturated fatty acid profile is associated with vascular endothelial function in patients with type 2 diabetes. Invited Reviewed

    Morioka T, Emoto M, Imamura S, Kakutani Y, Yamazaki Y, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Inaba M

    Diabetes & vascular disease research   15 ( 4 )   352 - 355   2018.07( ISSN:1479-1641

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    DOI: 10.1177/1479164118774314

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  • Local Melting of Gold Thin Films by Femtosecond Laser-Interference Processing to Generate Nanoparticles on a Source Target. Invited Reviewed

    Nakata Y, Murakawa K, Miyanaga N, Narazaki A, Shoji T, Tsuboi Y

    Nanomaterials (Basel, Switzerland)   8 ( 7 )   2018.06( ISSN:2079-4991

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    DOI: 10.3390/nano8070477

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  • Simultaneously Measured Interarm Blood Pressure Difference and Stroke: An Individual Participants Data Meta-Analysis. Invited Reviewed

    Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A, collaborative group for J-BAVEL-IAD (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies to Examine the Significance of Inter-Arm Blood Pressure Difference)

    Hypertension (Dallas, Tex. : 1979)   71 ( 6 )   1030 - 1038   2018.06( ISSN:0194-911X

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    DOI: 10.1161/HYPERTENSIONAHA.118.10923

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  • Correlation analysis of monocyte subsets and insulin resistance considering fetuin-A involvement in patients with type 2 diabetes. Invited Reviewed

    Maruo S, Mori K, Motoyama K, Nakamura M, Kawarabayashi R, Kakutani Y, Yamazaki Y, Morioka T, Shoji T, Inaba M, Emoto M

    Clinical and translational medicine   7 ( 1 )   9   2018.03( ISSN:2001-1326

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    DOI: 10.1186/s40169-018-0187-4

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  • 著明な高血糖を合併した2型糖尿病血液透析患者の2例 Invited Reviewed

    宮部 美月, 田畑 勉, 土蔵 尚子, 下村 菜生子, 西澤 良記, 辻本 吉広, 庄司 哲雄, 絵本 正憲, 稲葉 雅章

    日本透析医学会雑誌   51 ( 3 )   223 - 228   2018.03( ISSN:1340-3451

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    著明な高血糖を合併した2型糖尿病血液透析患者の2例を経験したので報告する。症例1(65歳、男性)は、入院時血糖値972mg/dLと著明な高血糖を示すも有効血漿浸透圧は292mOsm/LでありHHSの基準を満たさなかった。インスリン治療と血液透析にて、高血糖は速やかに改善した。症例2(90歳、女性)は、遷延性意識障害にて経管栄養がされており、入院時の血糖値994mg/dL、有効血漿浸透圧321mOsm/LとHHSの基準を満たした。入院当日の血液透析は施行せず、インスリン治療のみで血糖コントロールを行ったが、血糖値が改善するのに時間を要し、多くのインスリン量を必要とした。同程度の著しい高血糖であっても、発症前の飲水が可能かによって、高浸透圧血症において異なった病態を示した。また、血液透析はインスリン治療と併用にて高血糖を速やかに改善した。(著者抄録)

  • Low sleep quality is associated with progression of arterial stiffness in patients with cardiovascular risk factors: HSCAA study. Invited Reviewed

    Kadoya M, Kurajoh M, Kakutani-Hatayama M, Morimoto A, Miyoshi A, Kosaka-Hamamoto K, Shoji T, Moriwaki Y, Inaba M, Koyama H

    Atherosclerosis   270   95 - 101   2018.03( ISSN:0021-9150

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    DOI: 10.1016/j.atherosclerosis.2018.01.039

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  • 血漿可溶性レプチン受容体値は2型糖尿病患者における膵β細胞機能障害と関連する(Plasma soluble leptin receptor levels are associated with pancreatic β-cell dysfunction in patients with type 2 diabetes) Invited Reviewed

    Morioka Tomoaki, Emoto Masanori, Yamazaki Yuko, Kurajoh Masafumi, Motoyama Koka, Mori Katsuhito, Fukumoto Shinya, Shioi Atsushi, Shoji Tetsuo, Inaba Masaaki

    Journal of Diabetes Investigation   9 ( 1 )   55 - 62   2018.01( ISSN:2040-1116

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    2型糖尿病患者における血漿可溶性レプチン受容体(Ob-R)値とインスリン耐性および膵β細胞機能の関連を調べた。2型糖尿病患者283例(男性60.1%、平均61±12歳)に対して、血漿可溶性Ob-R値およびレプチン値をELISA法で測定した。インスリン抵抗性指数(HOMA-IR)、β細胞機能のホメオスタシスモデルアセスメント(HOMA-β)、Cペプチドインデックスを計算した。血漿レプチン中央値は3.4ng/mL、可溶性Ob-R中央値は23.6ng/mLであった。血漿レプチン値はHOMA-IR、HOMA-β、Cペプチドインデックスと強く且つ正に関連した。血漿可溶性Ob-R値はHOMA-β、Cペプチド指標と強く且つ負に関連したが、HOMA-IRとは弱く関連した。血漿可溶性Ob-R値、血漿レプチン値、スルホニル尿素の使用、年齢、性別、BMI、および他の共変量を含む多変量解析では、可溶性Ob-R値はHOMA-β、Cペプチドインデックスと独立に負に関連したが、HOMA-IRには有意に関連しなかった。可溶性Ob-Rが肥満と循環レプチン値から独立して、膵β細胞のインスリン分泌機能に影響を及ぼす因子の一つであることが示唆された。

  • Altered Serum n-6 Polyunsaturated Fatty Acid Profile and Risks of Mortality and Cardiovascular Events in a Cohort of Hemodialysis Patients. Invited Reviewed

    Kuwamura Y, Shoji T, Okute Y, Yamazaki Y, Motoyama K, Morioka T, Mori K, Fukumoto S, Tsujimoto Y, Shioi A, Emoto M, Inaba M

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   28 ( 1 )   54 - 63   2018.01( ISSN:1051-2276

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    DOI: 10.1053/j.jrn.2017.07.001

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  • Plasma soluble leptin receptor levels are associated with pancreatic β-cell dysfunction in patients with type 2 diabetes. Invited Reviewed

    Morioka T, Emoto M, Yamazaki Y, Kurajoh M, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Inaba M

    Journal of diabetes investigation   9 ( 1 )   55 - 62   2018.01( ISSN:2040-1116

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    DOI: 10.1111/jdi.12657

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  • 【心血管疾患予防を見据えたミネラル代謝異常の管理】 Invited Reviewed

    庄司 哲雄

    Astellas Square: 明日の医療を考える   13 ( 6 )   4 - 10   2017.12( ISSN:1880-0319

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  • 【透析療法のNew Concept-各種ガイドラインに基づく診療のポイント】<合併症への対応策> 血管石灰化 CKD-MBD診療ガイドラインに基づいた管理 Invited Reviewed

    辻本 吉広, 庄司 哲雄

    臨床泌尿器科   71 ( 11 )   920 - 926   2017.10( ISSN:0385-2393

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    <ポイント>血管石灰化は慢性腎臓病に伴う骨・ミネラル代謝異常(CKD-MBD)という概念のなかで予後に影響する重要な因子である.CKD-MBDについて日本透析医学会,KDIGOからそれぞれ診療ガイドラインが発行されている.石灰化の出現と進行予防を目指すべく,リスク因子の管理を行う.そのなかでもP,Ca,PTHの管理は重要であり,特にCa非含有P吸着薬の果たす役割は大きいと期待されている.(著者抄録)

  • 日本における脳心血管疾患予防のための包括的リスク管理(Comprehensive risk management for the prevention of cerebro-cardiovascular diseases in Japan) Invited Reviewed

    Teramoto Tamio, Yokode Masayuki, Iso Hiroyasu, Kitamura Akihiko, Shiomi Hiroki, Kimura Tsuyoshi, Matsumoto Masayasu, Iida Mami, Sasaki Jun, Inoue Shigeru, Nagatomi Ryouichi, Shoji Tetsuo, Arai Hidenori, Rakugi Hiromi, Sone Hirohito, Yamashita Shizuya, Mizyzaki Shigeru, Joint Committee for Comprehensive Risk Management Chart for the Prevention of Cerebro-Cardiovascular Diseases, The Japanese Society of Internal Medicine, the Japan Epidemiological Association, the Japa-nese Society of Hypertension, the Japanese Circulation Society, the Japanese Society of Nephrology, the Japanese Society of Physical Fitness and Sports Medicine, the Japan Diabetes Society, the Japan Atherosclerosis Society, the Japan Stroke Society, the Japan Society for the Study of Obesity, the Japan Geriatrics Society, the Japanese Association of Medical Sciences, the Japan Medical Association

    Clinical and Experimental Nephrology   21 ( 5 )   743 - 754   2017.10( ISSN:1342-1751

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  • Optical tweezing and binding at high irradiation powers on black-Si. Invited Reviewed

    Shoji T, Mototsuji A, Balčytis A, Linklater D, Juodkazis S, Tsuboi Y

    Scientific reports   7 ( 1 )   12298   2017.09

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    DOI: 10.1038/s41598-017-12470-9

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  • Proposed Cutoff Value of Brachial-Ankle Pulse Wave Velocity for the Management of Hypertension. Invited Reviewed

    Ohkuma T, Tomiyama H, Ninomiya T, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A, Collaborative Group for Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies (J-BAVEL)

    Circulation journal : official journal of the Japanese Circulation Society   81 ( 10 )   1540 - 1542   2017.09( ISSN:1346-9843

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    DOI: 10.1253/circj.CJ-17-0636

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  • 高血圧管理における上腕-足首間脈波伝播速度のカットオフ値の提案(Proposed Cutoff Value of Brachial-Ankle Pulse Wave Velocity for the Management of Hypertension) Invited Reviewed

    Ohkuma Toshiaki, Tomiyama Hirofumi, Ninomiya Toshiharu, Kario Kazuomi, Hoshide Satoshi, Kita Yoshikuni, Inoguchi Toyoshi, Maeda Yasutaka, Kohara Katsuhiko, Tabara Yasuharu, Nakamura Motoyuki, Ohkubo Takayoshi, Watada Hirotaka, Munakata Masanori, Ohishi Mitsuru, Ito Norihisa, Nakamura Michinari, Shoji Tetsuo, Vlachopoulos Charalambos, Yamashina Akira, the Collaborative Group for Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies(J-BAVEL)

    Circulation Journal   81 ( 10 )   1540 - 1542   2017.09( ISSN:1346-9843

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    上腕-足首間脈波伝播速度(baPWV)と心血管疾患(CVD)の発症リスクとの関連に関して、被験者個人データ(IPD)に基づくメタ解析を行った。解析対象とした試験は、Ehime Study、久山町研究、Iwate Study、大迫研究、高島研究、J-HOP study(日本人における家庭血圧の心血管予後推定能に関する研究)、NOAH study(高血圧患者コホート研究)、九州動脈硬化予防研究の8研究で、各試験に登録された高血圧症患者7656例を対象とした。被験者の46%は男性で、平均年齢は64歳であった。年齢と性別で調整したCVD発症のハザード比はbaPWVの増加に応じて有意に上昇した。ROC分析(曲線下面積は0.629)でCVD発症を予測するbaPWVのカットオフ値を18.3m/sと設定した場合、感度は56.2%、特異度は63.4%であった。この至適カットオフ値は交絡因子の調整後もCVDの発症を有意に予測した。

  • 透析患者の転倒 危険因子、合併症、生命予後との関連 Invited Reviewed

    松藤 勝太, 辻本 吉広, 西村 眞理, 矢野 嘉昭, 西澤 良記, 庄司 哲雄

    大阪透析研究会会誌   35 ( 2 )   105 - 109   2017.09( ISSN:0912-6937

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  • 【脂質異常症治療の新たな展開:ペマフィブラートへの期待】高TG血症と慢性腎臓病 Invited Reviewed

    庄司 哲雄

    Progress in Medicine   37 ( 9 )   1061 - 1065   2017.09( ISSN:0287-3648

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  • Both low and high serum ferritin levels predict mortality risk in hemodialysis patients without inflammation. Invited Reviewed

    Shoji T, Niihata K, Fukuma S, Fukuhara S, Akizawa T, Inaba M

    Clinical and experimental nephrology   21 ( 4 )   685 - 693   2017.08( ISSN:1342-1751

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    DOI: 10.1007/s10157-016-1317-1

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  • 炎症のない血液透析患者における血清フェリチン低値・高値はいずれも死亡リスクを予測する(Both low and high serum ferritin levels predict mortality risk in hemodialysis patients without inflammation) Invited Reviewed

    Shoji Tetsuo, Niihata Kakuya, Fukuma Shingo, Fukuhara Shunichi, Akizawa Tadao, Inaba Masaaki

    Clinical and Experimental Nephrology   21 ( 4 )   685 - 693   2017.08( ISSN:1342-1751

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    血液透析患者を対象に、血清フェリチン濃度と有害転帰の関連を調べる観察的コホート研究を実施した。対象はDialysis Outcomes and Practice Patterns Study(DOPPS)III(2005〜2008年)またはDOPPS IV(2009〜2012年)に参加した日本人血液透析患者2606例とした。関連する交絡因子に対する補正後、C反応性蛋白(CRP)低値群で血清フェリチンおよび総死亡率との間にU字型の関連が認められたが、CRP高値群では有意な関連は示されなかった。一方、CRP低値群およびCRP高値群の両群で血清フェリチンと心血管入院の間に線形関係が認められた。血清アルブミンにて階層化した全コホートにおいても、同様の結果が得られた。以上から、血液透析患者において炎症のある群と炎症のない群で血清フェリチンは全死因死亡率との間に異なるパターンを示した。一方、血清フェリチンと心血管入院の関連は炎症の有無にかかわらず同等であった。

  • 日本における脳血管障害予防に関する包括的リスク管理(Comprehensive risk management for the prevention of cerebro-cardiovascular diseases in Japan) Invited Reviewed

    Teramoto Tamio, Yokode Masayuki, Iso Hiroyasu, Kitamura Akihiko, Shiomi Hiroki, Kimura Tsuyoshi, Matsumoto Masayasu, Iida Mami, Sasaki Jun, Inoue Shigeru, Nagatomi Ryouichi, Shoji Tetsuo, Arai Hidenori, Rakugi Hiromi, Sone Hirohito, Yamashita Shizuya, Miyazaki Shigeru, The Joint Committee for Comprehensive Risk Management Chart for the Prevention of Cerebro-Cardiovascular Diseases

    Geriatrics & Gerontology International   17 ( 8 )   1145 - 1154   2017.08( ISSN:1444-1586

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  • 【腎臓病ガイドライン総まとめ 薬物治療のエッセンスが全部わかる!】(第4章)CKDの薬物治療(症候別) 脂質代謝異常 Invited Reviewed

    桑村 幸伸, 庄司 哲雄

    薬事   59 ( 10 )   2060 - 2066   2017.07( ISSN:0016-5980

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    <Key Points>脂質異常は粥状動脈硬化性心血管疾患(ASCVD)の危険因子であるが、病期の進んだ慢性腎臓病(CKD)ではLDL-CとCVDリスクの関連が弱まると報告されている。いずれのCKD病期においても、スタチンはLDL-C低下作用を示す。スタチンによるASCVDリスクの抑制効果は、CKDステージ3で著明であるのに対し、透析症例では有意でない。病期の進んだCKDステージG3前後では粥腫の成長が顕著であるが、さらにステージが進むと石灰化が主体となる。病期の進んだCKDでは非粥状動脈硬化性心血管疾患(non-ASCVD)の割合が大きいため、むしろミネラル代謝異常に対するマネージメントが重要となる。(著者抄録)

  • 日本における脳心血管疾患の予防のための包括的リスク管理(Comprehensive Risk Management for the Prevention of Cerebro-Cardiovascular Diseases in Japan) Invited Reviewed

    Teramoto Tamio, Yokode Masayuki, Iso Hiroyasu, Kitamura Akihiko, Shiomi Hiroki, Kimura Tsuyoshi, Matsumoto Masayasu, Iida Mami, Sasaki Jun, Inoue Shigeru, Nagatomi Ryouichi, Shoji Tetsuo, Arai Hidenori, Rakugi Hiromi, Sone Hirohito, Yamashita Shizuya, Miyazaki Shigeru, Joint Committee for Comprehensive Risk Management Chart for the Prevention of Cerebro-Cardiovascular Diseases, The Japanese Society of Internal Medicine, the Japan Epidemiological Association, the Japanese Society of Hypertension, the Japanese Circulation Society, the Japanese Society of Nephrology, the Japanese Society of Physical Fitness and Sports Medicine, the Japan Diabetes Society, the Japan Atherosclerosis Society, the Japan Stroke Society, the Japan Society for the Study of Obesity, the Japan Geriatrics Society, the Japanese Association of Medical Sciences, the Japan Medical Association

    Journal of Atherosclerosis and Thrombosis   24 ( 7 )   749 - 764   2017.07( ISSN:1340-3478

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  • Plasma homocysteine and cerebral small vessel disease as possible mediators between kidney and cognitive functions in patients with diabetes mellitus. Invited Reviewed

    Sonoda M, Shoji T, Kuwamura Y, Okute Y, Naganuma T, Shima H, Motoyama K, Morioka T, Mori K, Fukumoto S, Shioi A, Shimono T, Fujii H, Kabata D, Shintani A, Emoto M, Inaba M

    Scientific reports   7 ( 1 )   4382   2017.06

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    DOI: 10.1038/s41598-017-04515-w

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  • Brachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease: An Individual Participant Data Meta-Analysis. Invited Reviewed

    Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A, Collaborative Group for J-BAVEL (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies)*

    Hypertension (Dallas, Tex. : 1979)   69 ( 6 )   1045 - 1052   2017.06( ISSN:0194-911X

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    DOI: 10.1161/HYPERTENSIONAHA.117.09097

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  • 【慢性腎臓病CKDの合併症対策】CKDの脂質代謝異常とその対応 Invited Reviewed

    庄司 哲雄

    成人病と生活習慣病   47 ( 6 )   685 - 689   2017.06( ISSN:1347-0418

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    慢性腎臓病(CKD)は心血管疾患(CVD)の高リスク病態であり、CKDに伴う脂質異常の関与が想定される。CKDに伴う脂質異常症には蛋白尿、腎機能、原疾患(糖尿病)の影響が認められる。腎機能が低い患者ほどCVDリスクは高いが、腎機能が低い患者ほど脂質異常症の関与の程度は小さいという疫学研究がある。脂質低下療法によるCVDリスク低下も同様で、透析導入前のCKD症例では有意なリスク低下があるものの、透析患者を対象とした介入試験ではリスク低下のエビデンスがない。海外の診療ガイドラインでは、脂質低下薬を使うかどうかを対象をみて判断する内容になっているが、わが国では治療目標値を定めるものが用いられている。(著者抄録)

  • Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study. Invited Reviewed

    Sakura T, Morioka T, Shioi A, Kakutani Y, Miki Y, Yamazaki Y, Motoyama K, Mori K, Fukumoto S, Shoji T, Emoto M, Inaba M

    Cardiovascular diabetology   16 ( 1 )   62   2017.05

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    DOI: 10.1186/s12933-017-0545-3

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  • Cardiothoracic Ratio as a Predictor of Cardiovascular Events in a Cohort of Hemodialysis Patients. Invited Reviewed

    Okute Y, Shoji T, Hayashi T, Kuwamura Y, Sonoda M, Mori K, Shioi A, Tsujimoto Y, Tabata T, Emoto M, Inaba M

    Journal of atherosclerosis and thrombosis   24 ( 4 )   412 - 421   2017.04( ISSN:1340-3478

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    DOI: 10.5551/jat.36426

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  • 血液透析患者コホートにおける心血管イベントの予測因子としての心胸郭比(Cardiothoracic Ratio as a Predictor of Cardiovascular Events in a Cohort of Hemodialysis Patients) Invited Reviewed

    Okute Yujiro, Shoji Tetsuo, Hayashi Tomoshige, Kuwamura Yukinobu, Sonoda Mika, Mori Katsuhito, Shioi Atsushi, Tsujimoto Yoshihiro, Tabata Tsutomu, Emoto Masanori, Inaba Masaaki

    Journal of Atherosclerosis and Thrombosis   24 ( 4 )   412 - 421   2017.04( ISSN:1340-3478

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    血液透析患者コホートにおける心血管疾患(CVD)イベントの予測因子としての心胸郭比(CTR)の有用性を、N末端プロ脳性ナトリウム利尿ペプチド(NT-proBNP)と比較検討した。対象は維持透析患者517例と健康対照122例で、主要予測因子はCTRおよび血清NT-proBNPであり、主要評価項目は5年時のCVDイベントであった。ベースライン時点で透析群は対照群よりもCTR中央値が高かった。透析群のCTRはNT-proBNPと有意に正相関した。5年間のフォローアップ期間中にCVDイベントが190例で発生した。多変量コックスモデルにおいて、CTRはCVDリスクと有意に関連した[ハザード比(HR)2.12]。NT-proBNPは3.27のHRを示した。予測因子としてCTRおよびNT-proBNPが同時に含まれたとき、NT-proBNPのみがCVDイベント、全死因死亡率およびCVD+全死因死亡率の複合の有意な予測因子であった。血液透析患者においてCTRはCVDの有意かつ独立した予測因子であった。

  • POTENTIAL ADVANTAGE OF REPAGLINIDE MONOTHERAPY IN GLYCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES AND SEVERE RENAL IMPAIRMENT. Invited Reviewed

    Mori K, Emoto M, Numaguchi R, Yamazaki Y, Urata H, Motoyama K, Morioka T, Shoji T, Inaba M

    Acta endocrinologica (Bucharest, Romania : 2005)   13 ( 2 )   133 - 137   2017.04( ISSN:1841-0987

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    DOI: 10.4183/aeb.2017.133

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  • Serum Macro TSH Level is Associated with Sleep Quality in Patients with Cardiovascular Risks - HSCAA Study. Invited Reviewed

    Kadoya M, Koyama S, Morimoto A, Miyoshi A, Kakutani M, Hamamoto K, Kurajoh M, Shoji T, Moriwaki Y, Koshiba M, Yamamoto T, Inaba M, Namba M, Koyama H

    Scientific reports   7   44387   2017.03

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    DOI: 10.1038/srep44387

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  • 【糖尿病患者の腎機能障害】腎症を伴った糖尿病患者の脂質代謝異常と心血管リスク Invited Reviewed

    庄司 哲雄

    内分泌・糖尿病・代謝内科   44 ( 3 )   195 - 201   2017.03( ISSN:1884-2917

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  • Highly Sensitive Detection of Organic Molecules on the Basis of a Poly(N-isopropylacrylamide) Microassembly Formed by Plasmonic Optical Trapping. Invited Reviewed

    Shoji T, Sugo D, Nagasawa F, Murakoshi K, Kitamura N, Tsuboi Y

    Analytical chemistry   89 ( 1 )   532 - 537   2017.01( ISSN:0003-2700

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    DOI: 10.1021/acs.analchem.6b04024

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  • Plasma brain-derived neurotrophic factor concentration is a predictor of chronic kidney disease in patients with cardiovascular risk factors - Hyogo Sleep Cardio-Autonomic Atherosclerosis study. Invited Reviewed

    Kurajoh M, Kadoya M, Morimoto A, Miyoshi A, Kanzaki A, Kakutani-Hatayama M, Hamamoto K, Shoji T, Moriwaki Y, Yamamoto T, Inaba M, Namba M, Koyama H

    PloS one   12 ( 6 )   e0178686   2017

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    DOI: 10.1371/journal.pone.0178686

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  • The Association between Monocyte Surface CD163 and Insulin Resistance in Patients with Type 2 Diabetes. Invited Reviewed

    Kawarabayashi R, Motoyama K, Nakamura M, Yamazaki Y, Morioka T, Mori K, Fukumoto S, Imanishi Y, Shioi A, Shoji T, Emoto M, Inaba M

    Journal of diabetes research   2017   6549242   2017( ISSN:2314-6745

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    DOI: 10.1155/2017/6549242

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  • 腎臓における脂質異常症ガイドライン Invited Reviewed

    庄司 哲雄

    腎臓内科・泌尿器科   4 ( 6 )   618 - 623   2016.12( ISSN:2188-9147

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  • Plasma leptin concentration is associated with fatigue severity in patients with cardiovascular risk factors - HSCAA study. Invited Reviewed

    Kurajoh M, Kadoya M, Morimoto A, Naka M, Miyoshi A, Kanzaki A, Kakutani-Hatayama M, Hamamoto K, Shoji T, Moriwaki Y, Yamamoto T, Inaba M, Namba M, Koyama H

    Psychoneuroendocrinology   74   7 - 12   2016.12( ISSN:0306-4530

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    DOI: 10.1016/j.psyneuen.2016.08.016

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  • 腎性貧血治療における鉄投与の考え方 血清フェリチン値とトランスフェリン飽和度を指標として投与量を判断 Invited Reviewed

    西 慎一, 庄司 哲雄

    日本医事新報   ( 4825 )   56 - 57   2016.10( ISSN:0385-9215

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  • 脂質異常症を合併したCKD患者への介入 保存期CKDにはスタチン単独、あるいはスタチン・エゼチミブ併用を推奨 Invited Reviewed

    庄司 哲雄, 常喜 信彦

    日本医事新報   ( 4823 )   60 - 61   2016.10( ISSN:0385-9215

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  • 【らくらくわかる!ケアにつなげる!透析患者の心臓と血管Q&A】透析期間が長くなると、心血管疾患のリスクは増すの? Invited Reviewed

    庄司 哲雄

    透析ケア   22 ( 10 )   927 - 928   2016.10( ISSN:1341-1489

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  • 【らくらくわかる!ケアにつなげる!透析患者の心臓と血管Q&A】透析患者のコレステロール値は高いほうがいいの?低いほうがいいの? Invited Reviewed

    庄司 哲雄

    透析ケア   22 ( 10 )   941 - 942   2016.10( ISSN:1341-1489

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  • Silent Cerebral Microbleeds and Longitudinal Risk of Renal and Cardiovascular Events in Patients with CKD. Invited Reviewed

    Shima H, Mori T, Ooi M, Sonoda M, Shoji T, Ishimura E, Okamura M, Ishizaka N, Inaba M

    Clinical journal of the American Society of Nephrology : CJASN   11 ( 9 )   1557 - 65   2016.09( ISSN:1555-9041

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    DOI: 10.2215/CJN.13481215

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  • Visceral Adiposity is Preferentially Associated with Vascular Stiffness Rather than Thickness in Men with Type 2 Diabetes. Invited Reviewed

    Morigami H, Morioka T, Yamazaki Y, Imamura S, Numaguchi R, Asada M, Motoyama K, Mori K, Fukumoto S, Shoji T, Emoto M, Inaba M

    Journal of atherosclerosis and thrombosis   23 ( 9 )   1067 - 79   2016.09( ISSN:1340-3478

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    DOI: 10.5551/jat.33399

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  • LDLコレステロール値が食事の影響を受ける期間は? Invited Reviewed

    庄司 哲雄

    日本医事新報   ( 4821 )   66 - 66   2016.09( ISSN:0385-9215

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    Publishing type:Research paper (scientific journal)  

  • 内臓脂肪症は2型糖尿病男性において血管厚よりも血管硬化度と主に関連する(Visceral Adiposity is Preferentially Associated with Vascular Stiffness Rather than Thickness in Men with Type 2 Diabetes) Invited Reviewed

    Morigami Hirokazu, Morioka Tomoaki, Yamazaki Yuko, Imamura Satoshi, Numaguchi Ryutaro, Asada Mariko, Motoyama Koka, Mori Katsuhito, Fukumoto Shinya, Shoji Tetsuo, Emoto Masanori, Inaba Masaaki

    Journal of Atherosclerosis and Thrombosis   23 ( 9 )   1067 - 1079   2016.09( ISSN:1340-3478

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    2型糖尿病患者161例(男性92例、女性69例、平均61±14歳)を対象に、総頸動脈壁厚と血管硬化度に対する内臓脂肪症の影響を調査した。血圧、胴囲を測定し、血液サンプルから生化学的パラメータを解析した。内臓脂肪面積(VFA)と皮下脂肪面積(SFA)をデュアル生体インピーダンス解析で測定し、総頸動脈の内中膜複合体厚(IMT)と硬化度パラメータβを超音波検査で測定した。男性ではVFAと胴囲が血管硬化度パラメータβと正に関連し、BMI、胴囲、SFAがIMTと負に関連した。女性では血管硬化度パラメータβやIMTに有意に関連する肥満関連指標はなかった。年齢や他の潜在的交絡因子の補正後の多変量回帰分析では、男性ではVFA、SFA、胴囲、BMIは硬化度パラメータβと独立して有意に関連し、これら肥満関連指標はIMTの決定因子ではなかった。2型糖尿病男性では内臓脂肪症は頸動脈硬化度に関連したが、厚さには関連しなかった。

  • 【包括的リスク管理と動脈硬化】包括的リスク管理 包括的リスクからみたCKD管理 Invited Reviewed

    庄司 哲雄

    動脈硬化予防   15 ( 3 )   58 - 61   2016.09( ISSN:1347-7056

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  • 【スタチン 明らかにされた有益性とその限界を実地臨床に活かす】動脈硬化性疾患におけるスタチンの位置づけと課題 慢性腎臓病 Invited Reviewed

    庄司 哲雄

    薬局   67 ( 9 )   2674 - 2678   2016.08( ISSN:0044-0035

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    <Key Points>慢性腎臓病(CKD)は粥状動脈硬化性心血管疾患(ASCVD)の高リスク病態である。CKDステージ3前後で粥腫の成長が大きく、ステージ5頃から石灰化が顕著になる。CKDの病期によらずスタチンはLDL-C(non-HDL-C)を低下させる。スタチンによるASCVD予防効果はステージ3で顕著であり、透析患者では効果が乏しくなる。CKDでは早期からの脂質低下療法が望ましい。(著者抄録)

  • 【フレイル(Frailty)】身体機能低下とその対策 栄養低下とその対策 Invited Reviewed

    辻本 吉広, 庄司 哲雄

    透析フロンティア   26 ( 3 )   6 - 14   2016.08( ISSN:0917-2114

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  • 【腎と透析診療指針2016】(第4章)慢性腎臓病(CKD) CKDにおける脂質管理 Invited Reviewed

    庄司 哲雄

    腎と透析   80 ( 増刊 )   140 - 144   2016.06( ISSN:0385-2156

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  • CKDと動脈硬化 Invited Reviewed

    庄司 哲雄

    Total Vascular Management   ( 1 )   33 - 36   2016.04( ISSN:2423-8481

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    慢性腎臓病(CKD)は脳心血管病(CVD)の高リスク病態であり、厳格な危険因子の管理が求められている。動脈壁は、Atherosclerosisに伴う壁肥厚のみならず、中膜病変も含めて壁硬化が進む。透析患者などの進行したCKD病期には血管石灰化が顕著になり、また心肥大も高頻度となり、古典的危険因子以外にも、リン・カルシウム代謝異常、尿毒素、腎性貧血、低栄養・炎症・消耗などの多様な因子の関与が想定される。脂質異常症は重要な危険因子であるが、透析患者ではスタチンによる脂質低下療法によるCVDリスク低下が観察されない。また、透析患者では血圧と死亡率の関連がU字型になり、降圧療法によるCVDリスク低下も確認されていない。現時点では、未透析CKDの段階で十分な危険因子管理を行うことが重要であると考えられている。(著者抄録)

  • 【脂質異常症の臨床 見落としていませんか】知っておくべき病態生理と診療の進め方 典型例から学ぶ 腎臓病と脂質異常 Invited Reviewed

    庄司 哲雄

    Medical Practice   33 ( 4 )   591 - 596   2016.04( ISSN:0910-1551

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  • 【循環器内科診療のコントラバーシー】LDLコレステロール低下療法 treat-to-targetか?fire-and-forgetか? Invited Reviewed

    庄司 哲雄

    循環器内科   79 ( 3 )   194 - 200   2016.03( ISSN:1884-2909

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  • 【透析室スタッフならおさえておきたい いまさら聞ける!?透析治療の常識・非常識】透析患者のからだの常識・非常識 透析患者の多くが透析導入前から動脈硬化や心疾患を有する Invited Reviewed

    辻本 吉広, 庄司 哲雄

    透析ケア   22 ( 3 )   236 - 237   2016.03( ISSN:1341-1489

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  • 【急性腎障害、慢性腎臓病-その常識は正しいか?-】透析期慢性腎臓病 その常識は正しいか? ビタミンD製剤は使用すべきである Invited Reviewed

    庄司 哲雄

    救急・集中治療   28 ( 3-4 )   285 - 288   2016.03( ISSN:1346-0935

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    <Point>活性型ビタミンD製剤(DVRA)投与の主眼は、二次性副甲状腺機能亢進症の管理である。観察研究からは透析患者におけるVDRA投与は非投与に比べ、総死亡・心血管死亡、呼吸器感染症入院などの低リスクと関連している。VDRA投与により上記のような臨床アウトカムに有益性が得られるかどうか、ランダム化比較試験の結果は未だない。(著者抄録)

  • 【ナゾ解き生化学おもしろ講座 イラストでわかる脂質・脂肪酸・コレステロールのはたらき】脂質 Invited Reviewed

    庄司 哲雄

    Nutrition Care   9 ( 1 )   10 - 11   2016.01( ISSN:1882-3343

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  • 【ナゾ解き生化学おもしろ講座 イラストでわかる脂質・脂肪酸・コレステロールのはたらき】脂質異常症 Invited Reviewed

    庄司 哲雄

    Nutrition Care   9 ( 1 )   16 - 17   2016.01( ISSN:1882-3343

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  • 【ナゾ解き生化学おもしろ講座 イラストでわかる脂質・脂肪酸・コレステロールのはたらき】脂質の代謝 Invited Reviewed

    庄司 哲雄

    Nutrition Care   9 ( 1 )   14 - 15   2016.01( ISSN:1882-3343

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  • Associations of Sleep Quality and Awake Physical Activity with Fluctuations in Nocturnal Blood Pressure in Patients with Cardiovascular Risk Factors. Invited Reviewed

    Kadoya M, Koyama H, Kurajoh M, Naka M, Miyoshi A, Kanzaki A, Kakutani M, Shoji T, Moriwaki Y, Yamamoto T, Inaba M, Namba M

    PloS one   11 ( 5 )   e0155116   2016

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    DOI: 10.1371/journal.pone.0155116

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  • Plasma C1q/TNF-Related Protein-9 Levels Are Associated with Atherosclerosis in Patients with Type 2 Diabetes without Renal Dysfunction. Invited Reviewed

    Asada M, Morioka T, Yamazaki Y, Kakutani Y, Kawarabayashi R, Motoyama K, Mori K, Fukumoto S, Shioi A, Shoji T, Emoto M, Inaba M

    Journal of diabetes research   2016   8624313   2016( ISSN:2314-6745

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    DOI: 10.1155/2016/8624313

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  • Linagliptin monotherapy compared with voglibose monotherapy in patients with type 2 diabetes undergoing hemodialysis: a 12-week randomized trial. Invited Reviewed

    Mori K, Emoto M, Shoji T, Inaba M

    BMJ open diabetes research & care   4 ( 1 )   e000265   2016( ISSN:2052-4897

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    DOI: 10.1136/bmjdrc-2016-000265

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  • Improved glycemic control with teneligliptin in patients with type 2 diabetes mellitus on hemodialysis: Evaluation by continuous glucose monitoring. Invited Reviewed

    Wada N, Mori K, Nakagawa C, Sawa J, Kumeda Y, Shoji T, Emoto M, Inaba M

    Journal of diabetes and its complications   29 ( 8 )   1310 - 3   2015.11( ISSN:1056-8727

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    DOI: 10.1016/j.jdiacomp.2015.07.002

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  • Indoxyl sulfate suppresses hepatic fetuin-A expression via the aryl hydrocarbon receptor in HepG2 cells. Invited Reviewed

    Ochi A, Mori K, Nakatani S, Emoto M, Morioka T, Motoyama K, Fukumoto S, Imanishi Y, Shoji T, Ishimura E, Inaba M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   30 ( 10 )   1683 - 92   2015.10( ISSN:0931-0509

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    DOI: 10.1093/ndt/gfv250

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  • Plasma leptin level is associated with cardiac autonomic dysfunction in patients with type 2 diabetes: HSCAA study. Invited Reviewed

    Kurajoh M, Koyama H, Kadoya M, Naka M, Miyoshi A, Kanzaki A, Kakutani-Hatayama M, Okazaki H, Shoji T, Moriwaki Y, Yamamoto T, Emoto M, Inaba M, Namba M

    Cardiovascular diabetology   14   117   2015.09

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    DOI: 10.1186/s12933-015-0280-6

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  • Cerebral Microbleeds Predict Intracerebral Hemorrhage in Hemodialysis Patients. Invited Reviewed

    Naganuma T, Takemoto Y, Shoji T, Ishimura E, Okamura M, Nakatani T

    Stroke   46 ( 8 )   2107 - 12   2015.08( ISSN:0039-2499

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    DOI: 10.1161/STROKEAHA.115.009324

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  • Oncostatin M Promotes Osteoblastic Differentiation of Human Vascular Smooth Muscle Cells Through JAK3-STAT3 Pathway. Invited Reviewed

    Kakutani Y, Shioi A, Shoji T, Okazaki H, Koyama H, Emoto M, Inaba M

    Journal of cellular biochemistry   116 ( 7 )   1325 - 33   2015.07( ISSN:0730-2312

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    DOI: 10.1002/jcb.25088

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  • Immediate therapeutic efficacy of low-density lipoprotein apheresis for drug-resistant nephrotic syndrome: evidence from the short-term results from the POLARIS Study. Invited Reviewed

    Muso E, Mune M, Hirano T, Hattori M, Kimura K, Watanabe T, Yokoyama H, Sato H, Uchida S, Wada T, Shoji T, Yuzawa Y, Takemura T, Sugiyama S, Nishizawa Y, Ogahara S, Yorioka N, Sakai S, Ogura Y, Yukawa S, Iino Y, Imai E, Matsuo S, Saito T

    Clinical and experimental nephrology   19 ( 3 )   379 - 86   2015.06( ISSN:1342-1751

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    DOI: 10.1007/s10157-014-0996-8

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  • Use of vitamin D receptor activator, incident cardiovascular disease and death in a cohort of hemodialysis patients. Invited Reviewed

    Shoji T, Marubayashi S, Shigematsu T, Iseki K, Tsubakihara Y, Committee of Renal Data Registry, Japanese Society for Dialysis Therapy

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   19 ( 3 )   235 - 44   2015.06( ISSN:1744-9979

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/1744-9987.12274

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  • A Prospective Observational Survey on the Long-Term Effect of LDL Apheresis on Drug-Resistant Nephrotic Syndrome. Invited Reviewed

    Muso E, Mune M, Hirano T, Hattori M, Kimura K, Watanabe T, Yokoyama H, Sato H, Uchida S, Wada T, Shoji T, Takemura T, Yuzawa Y, Ogahara S, Sugiyama S, Iino Y, Sakai S, Ogura Y, Yukawa S, Nishizawa Y, Yorioka N, Imai E, Matsuo S, Saito T

    Nephron extra   5 ( 2 )   58 - 66   2015.05( ISSN:1664-5529

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    DOI: 10.1159/000437338

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  • Response to comment on Imamura et al. Plasma polyunsaturated fatty acid profile and delta-5 desaturase activity are altered in patients with type 2 diabetes. Metabolism 2014;63(11):1432-8. Invited Reviewed

    Imamura S, Morioka T, Yamazaki Y, Numaguchi R, Urata H, Motoyama K, Mori K, Fukumoto S, Shoji T, Emoto M, Inaba M

    Metabolism: clinical and experimental   64 ( 4 )   e3 - 4   2015.04( ISSN:0026-0495

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    DOI: 10.1016/j.metabol.2014.12.006

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  • Advantage of insulin glulisine over regular insulin in patients with type 2 diabetes and severe renal insufficiency. Invited Reviewed

    Urata H, Mori K, Emoto M, Yamazaki Y, Motoyama K, Morioka T, Fukumoto S, Koyama H, Shoji T, Ishimura E, Inaba M

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   25 ( 2 )   129 - 34   2015.03( ISSN:1051-2276

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    DOI: 10.1053/j.jrn.2014.07.011

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  • Endocrine and metabolic changes affecting cardiovascular disease in dialysis patients. Invited Reviewed

    Shoji T, Emoto M, Nishizawa Y, Inaba M

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   25 ( 2 )   223 - 5   2015.03( ISSN:1051-2276

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/j.jrn.2014.10.018

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  • Sleep, cardiac autonomic function, and carotid atherosclerosis in patients with cardiovascular risks: HSCAA study. Invited Reviewed

    Kadoya M, Koyama H, Kurajoh M, Kanzaki A, Kakutani-Hatayama M, Okazaki H, Shoji T, Moriwaki Y, Yamamoto T, Emoto M, Inaba M, Namba M

    Atherosclerosis   238 ( 2 )   409 - 14   2015.02( ISSN:0021-9150

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    DOI: 10.1016/j.atherosclerosis.2014.12.032

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  • A method for an approximate determination of a polymer-rich-domain concentration in phase-separated poly(N-isopropylacrylamide) aqueous solution by means of confocal Raman microspectroscopy combined with optical tweezers. Invited Reviewed

    Shoji T, Nohara R, Kitamura N, Tsuboi Y

    Analytica chimica acta   854   118 - 21   2015.01( ISSN:0003-2670

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    DOI: 10.1016/j.aca.2014.11.001

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  • Effect of chair stand exercise on activity of daily living: a randomized controlled trial in hemodialysis patients. Invited Reviewed

    Matsufuji S, Shoji T, Yano Y, Tsujimoto Y, Kishimoto H, Tabata T, Emoto M, Inaba M

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   25 ( 1 )   17 - 24   2015.01( ISSN:1051-2276

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    DOI: 10.1053/j.jrn.2014.06.010

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  • Current Focuses in Serum Lipid Abnormalities in Dialysis Patients. Invited Reviewed

    Shoji T

    Blood purification   40 ( 4 )   326 - 31   2015( ISSN:0253-5068

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    DOI: 10.1159/000441581

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  • Injectable cell scaffold restores impaired cell-based therapeutic angiogenesis in diabetic mice with hindlimb ischemia. Invited Reviewed

    Takeda K, Fukumoto S, Motoyama K, Morioka T, Mori K, Kageyama K, Sakai Y, Sato H, Suzuki M, Koyama H, Shoji T, Ishimura E, Emoto M, Furuzono T, Nakajima K, Inaba M

    Biochemical and biophysical research communications   454 ( 1 )   119 - 24   2014.11( ISSN:0006-291X

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    DOI: 10.1016/j.bbrc.2014.10.045

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  • Plasma polyunsaturated fatty acid profile and delta-5 desaturase activity are altered in patients with type 2 diabetes. Invited Reviewed

    Imamura S, Morioka T, Yamazaki Y, Numaguchi R, Urata H, Motoyama K, Mori K, Fukumoto S, Shoji T, Emoto M, Inaba M

    Metabolism: clinical and experimental   63 ( 11 )   1432 - 8   2014.11( ISSN:0026-0495

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    DOI: 10.1016/j.metabol.2014.08.003

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  • Plasmonic Optical Tweezers toward Molecular Manipulation: Tailoring Plasmonic Nanostructure, Light Source, and Resonant Trapping. Invited Reviewed

    Shoji T, Tsuboi Y

    The journal of physical chemistry letters   5 ( 17 )   2957 - 67   2014.09

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    DOI: 10.1021/jz501231h

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  • Comparison of effects of pioglitazone and glimepiride on plasma soluble RAGE and RAGE expression in peripheral mononuclear cells in type 2 diabetes: randomized controlled trial (PioRAGE). Invited Reviewed

    Koyama H, Tanaka S, Monden M, Shoji T, Morioka T, Fukumoto S, Mori K, Emoto M, Shoji T, Fukui M, Fujii H, Nishizawa Y, Inaba M

    Atherosclerosis   234 ( 2 )   329 - 34   2014.06( ISSN:0021-9150

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    DOI: 10.1016/j.atherosclerosis.2014.03.025

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  • Serum lipids and prevention of atherosclerotic cardiovascular events in hemodialysis patients. Invited Reviewed

    Shoji T

    Clinical and experimental nephrology   18 ( 2 )   257 - 60   2014.04( ISSN:1342-1751

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10157-013-0871-z

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  • Kidney function, cholesterol absorption and remnant lipoprotein accumulation in patients with diabetes mellitus. Invited Reviewed

    Sonoda M, Shoji T, Kimoto E, Okute Y, Shima H, Naganuma T, Motoyama K, Morioka T, Mori K, Fukumoto S, Shioi A, Koyama H, Emoto M, Inaba M

    Journal of atherosclerosis and thrombosis   21 ( 4 )   346 - 54   2014( ISSN:1340-3478

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    DOI: 10.5551/jat.20594

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  • Plasma brain-derived neurotrophic factor and reverse dipping pattern of nocturnal blood pressure in patients with cardiovascular risk factors. Invited Reviewed

    Kadoya M, Koyama H, Kanzaki A, Kurajoh M, Hatayama M, Shiraishi J, Okazaki H, Shoji T, Moriwaki Y, Yamamoto T, Inaba M, Namba M

    PloS one   9 ( 8 )   e105977   2014

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    DOI: 10.1371/journal.pone.0105977

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  • Cerebral white matter hyperintensity predicts cardiovascular events in haemodialysis patients. Invited Reviewed

    Naganuma T, Takemoto Y, Shoji T, Shima H, Ishimura E, Okamura M, Nakatani T

    Nephrology (Carlton, Vic.)   18 ( 10 )   676 - 81   2013.10( ISSN:1320-5358

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    DOI: 10.1111/nep.12115

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  • Autonomic function is associated with health-related quality of life in patients with end-stage renal disease: a case-control study. Invited Reviewed

    Fujii H, Koyama H, Fukuda S, Tokai H, Tajima S, Koizumi J, Yamaguti K, Kuratsune H, Watanabe Y, Hirayama Y, Shoji T, Inaba M, Nishizawa Y

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   23 ( 5 )   340 - 7   2013.09( ISSN:1051-2276

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    DOI: 10.1053/j.jrn.2012.12.008

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  • Serum n-3 and n-6 polyunsaturated fatty acid profile as an independent predictor of cardiovascular events in hemodialysis patients. Invited Reviewed

    Shoji T, Kakiya R, Hayashi T, Tsujimoto Y, Sonoda M, Shima H, Mori K, Fukumoto S, Tahara H, Shioi A, Tabata T, Emoto M, Nishizawa Y, Inaba M

    American journal of kidney diseases : the official journal of the National Kidney Foundation   62 ( 3 )   568 - 76   2013.09( ISSN:0272-6386

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    DOI: 10.1053/j.ajkd.2013.02.362

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  • Tumor necrosis factor-related apoptosis-inducing ligand as an independent predictor of mortality in hemodialysis patents. Invited Reviewed

    Mori K, Okuno S, Shoji T, Emoto M, Kakutani Y, Yamakawa K, Imanishi Y, Ishimura E, Yamakawa T, Shoji S, Inaba M

    Cytokine   61 ( 3 )   912 - 6   2013.03( ISSN:1043-4666

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    DOI: 10.1016/j.cyto.2012.12.030

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  • Receptor for advanced glycation end products regulates adipocyte hypertrophy and insulin sensitivity in mice: involvement of Toll-like receptor 2. Invited Reviewed

    Monden M, Koyama H, Otsuka Y, Morioka T, Mori K, Shoji T, Mima Y, Motoyama K, Fukumoto S, Shioi A, Emoto M, Yamamoto Y, Yamamoto H, Nishizawa Y, Kurajoh M, Yamamoto T, Inaba M

    Diabetes   62 ( 2 )   478 - 89   2013.02( ISSN:0012-1797

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    DOI: 10.2337/db11-1116

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  • Clinical impact of the leptin to soluble leptin receptor ratio on subclinical carotid atherosclerosis in patients with type 2 diabetes. Invited Reviewed

    Yamazaki Y, Emoto M, Morioka T, Kawano N, Lee E, Urata H, Tsuchikura S, Motoyama K, Mori K, Fukumoto S, Shoji T, Nishizawa Y, Inaba M

    Journal of atherosclerosis and thrombosis   20 ( 2 )   186 - 94   2013( ISSN:1340-3478

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    DOI: 10.5551/jat.14662

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  • Hair magnesium, but not serum magnesium, is associated with left ventricular wall thickness in hemodialysis patients. Invited Reviewed

    Ochi A, Ishimura E, Tsujimoto Y, Kakiya R, Tabata T, Mori K, Fukumoto S, Tahara H, Shoji T, Yasuda H, Nishizawa Y, Inaba M

    Circulation journal : official journal of the Japanese Circulation Society   77 ( 12 )   3029 - 36   2013( ISSN:1346-9843

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    DOI: 10.1253/circj.cj-13-0347

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  • Undercarboxylated osteocalcin does not correlate with insulin resistance as assessed by euglycemic hyperinsulinemic clamp technique in patients with type 2 diabetes mellitus. Invited Reviewed

    Mori K, Emoto M, Motoyama K, Lee E, Yamada S, Morioka T, Imanishi Y, Shoji T, Inaba M

    Diabetology & metabolic syndrome   4 ( 1 )   53   2012.12

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/1758-5996-4-53

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  • Decreased serum adrenal androgen dehydroepiandrosterone sulfate and mortality in hemodialysis patients. Invited Reviewed

    Kakiya R, Shoji T, Hayashi T, Tatsumi-Shimomura N, Tsujimoto Y, Tabata T, Shima H, Mori K, Fukumoto S, Tahara H, Koyama H, Emoto M, Ishimura E, Nishizawa Y, Inaba M

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   27 ( 10 )   3915 - 22   2012.10( ISSN:0931-0509

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/gfs162

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  • Impact of atherosclerosis on the relationship of glycemic control and mortality in diabetic patients on hemodialysis. Invited Reviewed

    Inaba M, Maekawa K, Okuno S, Imanishi Y, Hayashino Y, Emoto M, Shoji T, Ishimura E, Yamakawa T, Nishizawa Y

    Clinical nephrology   78 ( 4 )   273 - 80   2012.10( ISSN:0301-0430

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5414/CN106940

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  • Factors associated with cerebral white matter hyperintensities in haemodialysis patients. Invited Reviewed

    Naganuma T, Takemoto Y, Shoji T, Shima H, Ishimura E, Okamura M, Nakatani T

    Nephrology (Carlton, Vic.)   17 ( 6 )   561 - 8   2012.08( ISSN:1320-5358

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1440-1797.2012.01596.x

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  • [Kidney and bone update : the 5-year history and future of CKD-MBD. Progress in therapy of CKD-MBD with vitamin D receptor activators]. Invited Reviewed

    Shoji T

    Clinical calcium   22 ( 7 )   1073 - 81   2012.07( ISSN:0917-5857

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • Antialbuminuric advantage of cilnidipine compared with L-type calcium channel blockers in type 2 diabetic patients with normoalbuminuria and microalbuminuria. Invited Reviewed

    Fukumoto S, Ishimura E, Motoyama K, Morioka T, Kimoto E, Wakikawa K, Shoji S, Koyama H, Shoji T, Emoto M, Nishizawa Y, Inaba M, Cilnidipine vs L-type calcium channel blockers Evaluation of Antihypertensive Renoprotective Effects in Diabetic patients (CLEARED) Study Investigators

    Diabetes research and clinical practice   97 ( 1 )   91 - 8   2012.07( ISSN:0168-8227

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.diabres.2012.01.024

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  • Poor muscle quality as a predictor of high mortality independent of diabetes in hemodialysis patients. Invited Reviewed

    Yoda M, Inaba M, Okuno S, Yoda K, Yamada S, Imanishi Y, Mori K, Shoji T, Ishimura E, Yamakawa T, Shoji S

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie   66 ( 4 )   266 - 70   2012.06( ISSN:0753-3322

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.biopha.2011.11.001

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  • Thrice-weekly insulin injection with nurse's support for diabetic hemodialysis patients having difficulty with self injection. Invited Reviewed

    Shoji T, Emoto M, Mori K, Morioka T, Fukumoto S, Takahashi T, Matsumoto A, Nishizawa Y, Inaba M

    Osaka city medical journal   58 ( 1 )   35 - 8   2012.06( ISSN:0030-6096

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    PubMed

  • [Chronic kidney disease (CKD)--recent progress. Topics: VI. Chronic kidney disease (CKD) and associated disorders; 4. Dyslipidemia in chronic kidney disease]. Invited Reviewed

    Shoji T

    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine   101 ( 5 )   1294 - 302   2012.05( ISSN:0021-5384

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2169/naika.101.1294

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  • Elemental concentrations in scalp hair, nutritional status and health-related quality of life in hemodialysis patients. Invited Reviewed

    Ochi A, Ishimura E, Tsujimoto Y, Kakiya R, Tabata T, Mori K, Tahara H, Shoji T, Yasuda H, Nishizawa Y, Inaba M

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   16 ( 2 )   127 - 33   2012.04( ISSN:1744-9979

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1744-9987.2011.01043.x

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  • Chronic kidney disease in urolithiasis patients following successful extracorporeal shockwave lithotripsy. Invited Reviewed

    Maeda S, Naganuma T, Takemoto Y, Shoji T, Okamura M, Nakatani T

    Molecular medicine reports   5 ( 1 )   3 - 6   2012.01( ISSN:1791-2997

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3892/mmr.2011.586

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  • Association of endothelial and vascular smooth muscle dysfunction with cardiovascular risk factors, vascular complications, and subclinical carotid atherosclerosis in type 2 diabetic patients. Invited Reviewed

    Kawano N, Emoto M, Mori K, Yamazaki Y, Urata H, Tsuchikura S, Motoyama K, Morioka T, Fukumoto S, Shoji T, Koyama H, Okuno Y, Nishizawa Y, Inaba M

    Journal of atherosclerosis and thrombosis   19 ( 3 )   276 - 84   2012( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.10629

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  • Enhancement of cell-based therapeutic angiogenesis using a novel type of injectable scaffolds of hydroxyapatite-polymer nanocomposite microspheres. Invited Reviewed

    Mima Y, Fukumoto S, Koyama H, Okada M, Tanaka S, Shoji T, Emoto M, Furuzono T, Nishizawa Y, Inaba M

    PloS one   7 ( 4 )   e35199   2012

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pone.0035199

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  • Disappearance of association in diabetic patients on hemodialysis between anemia and mortality risk: the Japan dialysis outcomes and practice pattern study. Invited Reviewed

    Inaba M, Hayashino Y, Shoji T, Akiba T, Akizawa T, Saito A, Kurokawa K, Fukuhara S

    Nephron. Clinical practice   120 ( 2 )   c91 - c100   2012

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000335979

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  • Chronic kidney disease, dyslipidemia, and atherosclerosis. Invited Reviewed

    Shoji T, Abe T, Matsuo H, Egusa G, Yamasaki Y, Kashihara N, Shirai K, Kashiwagi A, Committee of Renal and Peripheral Arteries, Japan Atherosclerosis Society

    Journal of atherosclerosis and thrombosis   19 ( 4 )   299 - 315   2012( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.10454

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  • Trace elements in the hair of hemodialysis patients. Invited Reviewed

    Ochi A, Ishimura E, Tsujimoto Y, Kakiya R, Tabata T, Mori K, Shoji T, Yasuda H, Nishizawa Y, Inaba M

    Biological trace element research   143 ( 2 )   825 - 34   2011.11( ISSN:0163-4984

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12011-010-8948-y

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  • Elevated non-high-density lipoprotein cholesterol (non-HDL-C) predicts atherosclerotic cardiovascular events in hemodialysis patients. Invited Reviewed

    Shoji T, Masakane I, Watanabe Y, Iseki K, Tsubakihara Y, Committee of Renal Data Registry, Japanese Society for Dialysis Therapy

    Clinical journal of the American Society of Nephrology : CJASN   6 ( 5 )   1112 - 20   2011.05( ISSN:1555-9041

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2215/CJN.09961110

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  • Advanced glycation end products, carotid atherosclerosis, and circulating endothelial progenitor cells in patients with end-stage renal disease. Invited Reviewed

    Ueno H, Koyama H, Fukumoto S, Tanaka S, Shoji T, Shoji T, Emoto M, Tahara H, Inaba M, Kakiya R, Tabata T, Miyata T, Nishizawa Y

    Metabolism: clinical and experimental   60 ( 4 )   453 - 9   2011.04( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2010.04.001

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  • Factors associated with silent cerebral microbleeds in hemodialysis patients. Invited Reviewed

    Naganuma T, Takemoto Y, Yamasaki T, Shima H, Shoji T, Ishimura E, Nishizawa Y, Morino M, Okamura M, Nakatani T

    Clinical nephrology   75 ( 4 )   346 - 55   2011.04( ISSN:0301-0430

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5414/cnp75346

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  • Association between chronic kidney disease and small residual urine volumes in patients with benign prostatic hyperplasia. Invited Reviewed

    Yamasaki T, Naganuma T, Iguchi T, Kuroki Y, Kuwabara N, Takemoto Y, Shoji T, Nakatani T

    Nephrology (Carlton, Vic.)   16 ( 3 )   335 - 9   2011.03( ISSN:1320-5358

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1440-1797.2010.01430.x

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  • Association of serum TRAIL levels with atherosclerosis in patients with type 2 diabetes mellitus. Invited Reviewed

    Kawano N, Mori K, Emoto M, Lee E, Kobayashi I, Yamazaki Y, Urata H, Morioka T, Koyama H, Shoji T, Nishizawa Y, Inaba M

    Diabetes research and clinical practice   91 ( 3 )   316 - 20   2011.03( ISSN:0168-8227

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.diabres.2010.11.034

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  • Comparison of the effect of cilostazol with aspirin on circulating endothelial progenitor cells and small-dense LDL cholesterol in diabetic patients with cerebral ischemia: a randomized controlled pilot trial. Invited Reviewed

    Ueno H, Koyama H, Mima Y, Fukumoto S, Tanaka S, Shoji T, Emoto M, Shoji T, Nishizawa Y, Inaba M

    Journal of atherosclerosis and thrombosis   18 ( 10 )   883 - 90   2011( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.9225

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  • Different effects of diabetic autonomic neuropathy on regional transcutaneous oxygen tension in patients with peripheral arterial disease. Invited Reviewed

    Mima Y, Fukumoto S, Ueno H, Koyama H, Tanaka S, Morioka T, Motoyama K, Emoto M, Shoji T, Nishizawa Y, Inaba M

    Osaka city medical journal   56 ( 2 )   27 - 36   2010.12( ISSN:0030-6096

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    PubMed

  • Regions of arterial stenosis and clinical factors determining transcutaneous oxygen tension in patients with peripheral arterial disease. Invited Reviewed

    Ueno H, Fukumoto S, Koyama H, Tanaka S, Maeno T, Murayama M, Otsuka Y, Mima Y, Kawaguchi Y, Shoji T, Inaba M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   17 ( 8 )   858 - 69   2010.08( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.3723

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  • Central versus peripheral arterial stiffness in association with coronary, cerebral and peripheral arterial disease. Invited Reviewed

    Tsuchikura S, Shoji T, Kimoto E, Shinohara K, Hatsuda S, Koyama H, Emoto M, Nishizawa Y

    Atherosclerosis   211 ( 2 )   480 - 5   2010.08( ISSN:0021-9150

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.atherosclerosis.2010.03.037

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  • Receptor for advanced glycation end-products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apoE-deficient mouse. Invited Reviewed

    Ueno H, Koyama H, Shoji T, Monden M, Fukumoto S, Tanaka S, Otsuka Y, Mima Y, Morioka T, Mori K, Shioi A, Yamamoto H, Inaba M, Nishizawa Y

    Atherosclerosis   211 ( 2 )   431 - 6   2010.08( ISSN:0021-9150

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.atherosclerosis.2010.04.006

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  • Fetuin-A is associated with calcified coronary artery disease. Invited Reviewed

    Mori K, Ikari Y, Jono S, Emoto M, Shioi A, Koyama H, Shoji T, Ishimura E, Inaba M, Hara K, Nishizawa Y

    Coronary artery disease   21 ( 5 )   281 - 5   2010.08( ISSN:0954-6928

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MCA.0b013e32832fe5d5

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  • Brachial-ankle pulse wave velocity as an index of central arterial stiffness. Invited Reviewed

    Tsuchikura S, Shoji T, Kimoto E, Shinohara K, Hatsuda S, Koyama H, Emoto M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   17 ( 6 )   658 - 65   2010.06( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.3616

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  • Fetuin-A and atherosclerotic calcified plaque in patients with type 2 diabetes mellitus. Invited Reviewed

    Emoto M, Mori K, Lee E, Kawano N, Yamazaki Y, Tsuchikura S, Morioka T, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Metabolism: clinical and experimental   59 ( 6 )   873 - 8   2010.06( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2009.10.005

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  • Arterial stiffness predicts cardiovascular death independent of arterial thickness in a cohort of hemodialysis patients. Invited Reviewed

    Shoji T, Maekawa K, Emoto M, Okuno S, Yamakawa T, Ishimura E, Inaba M, Nishizawa Y

    Atherosclerosis   210 ( 1 )   145 - 9   2010.05( ISSN:0021-9150

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.atherosclerosis.2009.11.013

    PubMed

  • Cerebral microbleeds in predialysis patients with chronic kidney disease. Invited Reviewed

    Shima H, Ishimura E, Naganuma T, Yamazaki T, Kobayashi I, Shidara K, Mori K, Takemoto Y, Shoji T, Inaba M, Okamura M, Nakatani T, Nishizawa Y

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   25 ( 5 )   1554 - 9   2010.05( ISSN:0931-0509

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/gfp694

    PubMed

  • Serum C-reactive protein and thioredoxin levels in subjects with mildly reduced glomerular filtration rate. Invited Reviewed

    Tsuchikura S, Shoji T, Shimomura N, Kakiya R, Emoto M, Koyama H, Ishimura E, Inaba M, Nishizawa Y

    BMC nephrology   11   7   2010.04

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/1471-2369-11-7

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  • Fatigue is a predictor for cardiovascular outcomes in patients undergoing hemodialysis. Invited Reviewed

    Koyama H, Fukuda S, Shoji T, Inaba M, Tsujimoto Y, Tabata T, Okuno S, Yamakawa T, Okada S, Okamura M, Kuratsune H, Fujii H, Hirayama Y, Watanabe Y, Nishizawa Y

    Clinical journal of the American Society of Nephrology : CJASN   5 ( 4 )   659 - 66   2010.04( ISSN:1555-9041

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2215/CJN.08151109

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  • Dialysis modality is independently associated with circulating endothelial progenitor cells in end-stage renal disease patients. Invited Reviewed

    Ueno H, Koyama H, Fukumoto S, Tanaka S, Shoji T, Shoji T, Emoto M, Tahara H, Tsujimoto Y, Tabata T, Nishizawa Y

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   25 ( 2 )   581 - 6   2010.02( ISSN:0931-0509

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/gfp358

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  • Effects of pravastatin on serum osteoprotegerin levels in patients with hypercholesterolemia and type 2 diabetes. Invited Reviewed

    Mori K, Jono S, Emoto M, Kawagishi T, Yasumoto H, Konishi T, Furumitsu Y, Shioi A, Shoji T, Inaba M, Nishizawa Y

    Angiology   61 ( 1 )   86 - 91   2010.02( ISSN:0003-3197

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/0003319708330525

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  • Plasma angiopoietin-like protein 3 (ANGPTL3) concentration is associated with uremic dyslipidemia. Invited Reviewed

    Shoji T, Hatsuda S, Tsuchikura S, Kimoto E, Kakiya R, Tahara H, Koyama H, Emoto M, Tabata T, Nishizawa Y

    Atherosclerosis   207 ( 2 )   579 - 84   2009.12( ISSN:0021-9150

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.atherosclerosis.2009.05.023

    PubMed

  • [Chronic kidney disease (CKD) and bone. Pleiotropic actions of vitamin D and survival advantage]. Invited Reviewed

    Shoji T, Nishizawa Y

    Clinical calcium   19 ( 4 )   514 - 21   2009.04( ISSN:0917-5857

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • The combination of IMT and stiffness parameter beta is highly associated with concurrent coronary artery disease in type 2 diabetes. Invited Reviewed

    Lee E, Emoto M, Teramura M, Tsuchikura S, Ueno H, Shinohara K, Morioka T, Mori K, Koyama H, Shoji T, Okuno Y, Inaba M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   16 ( 1 )   33 - 9   2009.03( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.e605

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  • Glimepiride increases high-density lipoprotein cholesterol via increasing adiponectin levels in type 2 diabetes mellitus. Invited Reviewed

    Araki T, Emoto M, Konishi T, Ikuno Y, Lee E, Teramura M, Motoyama K, Yokoyama H, Mori K, Koyama H, Shoji T, Nishizawa Y

    Metabolism: clinical and experimental   58 ( 2 )   143 - 8   2009.02( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2008.09.006

    PubMed

  • Small dense low-density lipoprotein cholesterol concentration and carotid atherosclerosis. Invited Reviewed

    Shoji T, Hatsuda S, Tsuchikura S, Shinohara K, Kimoto E, Koyama H, Emoto M, Nishizawa Y

    Atherosclerosis   202 ( 2 )   582 - 8   2009.02( ISSN:0021-9150

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.atherosclerosis.2008.04.042

    PubMed

  • Skin autofluorescence, a marker for advanced glycation end product accumulation, is associated with arterial stiffness in patients with end-stage renal disease. Invited Reviewed

    Ueno H, Koyama H, Tanaka S, Fukumoto S, Shinohara K, Shoji T, Emoto M, Tahara H, Kakiya R, Tabata T, Miyata T, Nishizawa Y

    Metabolism: clinical and experimental   57 ( 10 )   1452 - 7   2008.10( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2008.05.016

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  • Effects of pioglitazone on serum fetuin-A levels in patients with type 2 diabetes mellitus. Invited Reviewed

    Mori K, Emoto M, Araki T, Yokoyama H, Lee E, Teramura M, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Metabolism: clinical and experimental   57 ( 9 )   1248 - 52   2008.09( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2008.04.019

    PubMed

  • Reverse epidemiology in hemodialysis patients. Lessons from Japanese registries. Invited Reviewed

    Shoji T, Tsubakihara Y, Nakai S, Nishizawa Y

    Nephrologie & therapeutique   4 ( 4 )   223 - 7   2008.07( ISSN:1769-7255

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.nephro.2008.01.005

    PubMed

  • Different risk factors for vascular calcification in end-stage renal disease between diabetics and nondiabetics: the respective importance of glycemic and phosphate control. Invited Reviewed

    Ishimura E, Okuno S, Taniwaki H, Kizu A, Tsuchida T, Shioi A, Shoji T, Tabata T, Inaba M, Nishizawa Y

    Kidney & blood pressure research   31 ( 1 )   10 - 5   2008( ISSN:1420-4096

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000112542

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  • Body fat measurement in chronic kidney disease: implications in research and clinical practice. Invited Reviewed

    Shoji T, Ishimura E, Nishizawa Y

    Current opinion in nephrology and hypertension   16 ( 6 )   572 - 6   2007.11( ISSN:1062-4821

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MNH.0b013e3282f0d22f

    PubMed

  • Clinical impact of metabolic syndrome by modified NCEP-ATPIII criteria on carotid atherosclerosis in Japanese adults. Invited Reviewed

    Teramura M, Emoto M, Araki T, Yokoyama H, Motoyama K, Shinohara K, Mori K, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   14 ( 4 )   172 - 8   2007.08( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.e505

    PubMed

  • [Effects of vitamin D on non-classical target organs and survival]. Invited Reviewed

    Shoji T, Nishizawa Y

    Clinical calcium   17 ( 5 )   691 - 7   2007.05( ISSN:0917-5857

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • Urinary albumin excretion associated with arterial wall stiffness rather than thickness in type 2 diabetic patients. Invited Reviewed

    Ishimura E, Taniwaki H, Tsuchida T, Obatake N, Emoto M, Shoji T, Shioi A, Inaba M, Nishizawa Y

    Journal of nephrology   20 ( 2 )   204 - 11   2007.03( ISSN:1121-8428

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • Association of serum fetuin-A with carotid arterial stiffness. Invited Reviewed

    Mori K, Emoto M, Araki T, Yokoyama H, Teramura M, Lee E, Motoyama K, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Clinical endocrinology   66 ( 2 )   246 - 50   2007.02( ISSN:0300-0664

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1365-2265.2006.02716.x

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  • Association between plasma angiopoietin-like protein 3 and arterial wall thickness in healthy subjects.

    Journal of Vascular Research   44   61 - 66   2007

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  • Low circulating endogenous secretory receptor for AGEs predicts cardiovascular mortality in patients with end-stage renal disease.

    Arteriosclerosis, Thrombosis& Vascular Biology   27   147 - 153   2007

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  • Platelet activation is associated with hypoadiponectinemia and carotid atherosclerosis. Invited Reviewed

    Shoji T, Koyama H, Fukumoto S, Maeno T, Yokoyama H, Shinohara K, Emoto M, Shoji T, Yamane T, Hino M, Shioi A, Nishizawa Y

    Atherosclerosis   188 ( 1 )   190 - 5   2006.09( ISSN:0021-9150

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.atherosclerosis.2005.10.034

    PubMed

  • Effect of adiponectin on carotid arterial stiffness in type 2 diabetic patients treated with pioglitazone and metformin. Invited Reviewed

    Araki T, Emoto M, Teramura M, Yokoyama H, Mori K, Hatsuda S, Maeno T, Shinohara K, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Metabolism: clinical and experimental   55 ( 8 )   996 - 1001   2006.08( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2006.03.008

    PubMed

  • Receptor for advanced glycation end products is involved in impaired angiogenic response in diabetes. Invited Reviewed

    Shoji T, Koyama H, Morioka T, Tanaka S, Kizu A, Motoyama K, Mori K, Fukumoto S, Shioi A, Shimogaito N, Takeuchi M, Yamamoto Y, Yonekura H, Yamamoto H, Nishizawa Y

    Diabetes   55 ( 8 )   2245 - 55   2006.08( ISSN:0012-1797

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/db05-1375

    PubMed

  • [Effects of vitamin D on the cardiovascular system]. Invited Reviewed

    Shoji T, Nishizawa Y

    Clinical calcium   16 ( 7 )   1107 - 14   2006.07( ISSN:0917-5857

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • The association of plasma adiponectin level with carotid arterial stiffness. Invited Reviewed

    Araki T, Emoto M, Yokoyama H, Maeno T, Hatsuda S, Mori K, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Metabolism: clinical and experimental   55 ( 5 )   587 - 92   2006.05( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2005.11.014

    PubMed

  • Plasma adiponectin level is associated with insulin-stimulated nonoxidative glucose disposal. Invited Reviewed

    Yokoyama H, Emoto M, Mori K, Araki T, Teramura M, Koyama H, Shoji T, Inaba M, Nishizawa Y

    The Journal of clinical endocrinology and metabolism   91 ( 1 )   290 - 4   2006.01( ISSN:0021-972X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/jc.2004-2549

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  • Impact of glycemic control on survival of diabetic patients on chronic regular hemodialysis: a 7-year observational study.

    Diabetes Care   29   1496 - 1500   2006

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    Publishing type:Research paper (scientific journal)  

  • Body fat mass and lean mass as predictors of survival in hemodialysis patients.

    Kidney International   70   549 - 556   2006

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    Publishing type:Research paper (scientific journal)  

  • Regional arterial stiffness associated with ischemic heart disease in type 2 diabetes mellitus.

    Journal of Atherosclerosis and Thrombosis   13   114 - 121   2006

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    Publishing type:Research paper (scientific journal)  

  • Regional arterial stiffness in patients with type 2 diabetes and chronic kidney disease.

    Journal of American Society of Nephrology   17   2245 - 2252   2006

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    Publishing type:Research paper (scientific journal)  

  • Plasma level of endogenous secretory RAGE is associated with components of the metabolic syndrome and atherosclerosis. Invited Reviewed

    Koyama H, Shoji T, Yokoyama H, Motoyama K, Mori K, Fukumoto S, Emoto M, Shoji T, Tamei H, Matsuki H, Sakurai S, Yamamoto Y, Yonekura H, Watanabe T, Yamamoto H, Nishizawa Y

    Arteriosclerosis, thrombosis, and vascular biology   25 ( 12 )   2587 - 93   2005.12( ISSN:1079-5642

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1161/01.ATV.0000190660.32863.cd

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  • Aortic calcification in haemodialysis patients with diabetes mellitus. Invited Reviewed

    Taniwaki H, Ishimura E, Tabata T, Tsujimoto Y, Shioi A, Shoji T, Inaba M, Inoue T, Nishizawa Y

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   20 ( 11 )   2472 - 8   2005.11( ISSN:0931-0509

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/gfi039

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  • Introduction to sevelamer hydrochloride and its clinical effects. Invited Reviewed

    Tahara H, Tsujimoto Y, Shoji T, Inaba M, Tabata T, Nishizawa Y

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   9 Suppl 1   S2 - 6   2005.08( ISSN:1744-9979

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1744-9987.2005.00279.x

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  • Insulin resistance index as a predictor for pioglitazone treatment in type 2 diabetes. Invited Reviewed

    Araki T, Emoto M, Yokoyama H, Motoyama K, Morioka T, Tahara H, Koyama H, Shoji T, Okuno Y, Inaba M, Nishizawa Y

    Osaka city medical journal   51 ( 1 )   19 - 25   2005.06( ISSN:0030-6096

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    Publishing type:Research paper (scientific journal)  

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  • Cross-sectional association of serum phosphate with carotid intima-medial thickness in hemodialysis patients. Invited Reviewed

    Ishimura E, Taniwaki H, Tabata T, Tsujimoto Y, Jono S, Emoto M, Shoji T, Inaba M, Inoue T, Nishizawa Y

    American journal of kidney diseases : the official journal of the National Kidney Foundation   45 ( 5 )   859 - 65   2005.05( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/j.ajkd.2005.02.008

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  • The K469E polymorphism of the intercellular adhesion molecule-1 gene is associated with plasma fibrinogen level in type 2 diabetes. Invited Reviewed

    Yokoyama H, Tahara H, Emoto M, Fujiwara S, Araki T, Shinohara K, Hatsuda S, Maeno T, Shoji T, Koyama H, Shoji T, Nishizawa Y

    Metabolism: clinical and experimental   54 ( 3 )   381 - 6   2005.03( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.metabol.2004.10.002

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  • Significance of intima-media thickness in femoral artery in the determination of calcaneus osteo-sono index but not of lumbar spine bone mass in healthy Japanese people. Invited Reviewed

    Yamada S, Inaba M, Goto H, Nagata M, Ueda M, Nakatuka K, Tahara H, Yokoyama H, Emoto M, Shoji T, Nishizawa Y

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA   16 ( 1 )   64 - 70   2005.01( ISSN:0937-941X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00198-004-1642-1

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  • Effect of atorvastatin on regional arterial stiffness in patients with type 2 diabetes mellitus.

    Journal of Atherosclerosis and Thrombosis   12   205 - 210   2005

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    Publishing type:Research paper (scientific journal)  

  • Altered relationship between body fat and plasma adiponectin in end-stage renal disease.

    Metabolism   54   330 - 334   2005

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    Publishing type:Research paper (scientific journal)   Kind of work:Single Work  

  • Platelet-monocyte aggregates are independently associated with occurrence of carotid plaques in type 2 diabetic patients. Invited Reviewed

    Shoji T, Koyama H, Fukumoto S, Maeno T, Yokoyama H, Shinohara K, Emoto M, Shoji T, Inaba M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   12 ( 6 )   344 - 52   2005( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.12.344

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  • C-reactive protein is a significant predictor of vascular calcification of both aorta and hand arteries. Reviewed

    Ishimura E, Okuno S, Kitatani K, Maekawa K, Izumotani T, Yamakawa T, Jono S, Shoji T, Shioi A, Inaba M, Massry SG, Nishizawa Y

    Seminars in nephrology   24 ( 5 )   408 - 12   2004.09( ISSN:0270-9295

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.semnephrol.2004.06.008

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  • Roles of metabolic and endocrinological alterations in atherosclerosis and cardiovascular disease in renal failure: another form of metabolic syndrome. Reviewed

    Nishizawa Y, Shoji T, Emoto M, Koyama H, Tahara H, Fukumoto S, Inaba M, Ishimura E, Miki T

    Seminars in nephrology   24 ( 5 )   423 - 5   2004.09( ISSN:0270-9295

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.semnephrol.2004.06.018

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  • [Vitamin D and survival of hemodialysis patients]. Invited Reviewed

    Shoji T, Nishizawa Y

    Clinical calcium   14 ( 9 )   64 - 8   2004.09( ISSN:0917-5857

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    PubMed

  • Short-term aerobic exercise improves arterial stiffness in type 2 diabetes. Reviewed

    Yokoyama H, Emoto M, Fujiwara S, Motoyama K, Morioka T, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Diabetes research and clinical practice   65 ( 2 )   85 - 93   2004.08( ISSN:0168-8227

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.diabres.2003.12.005

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  • Effect of aerobic exercise on plasma adiponectin levels and insulin resistance in type 2 diabetes. Reviewed

    Yokoyama H, Emoto M, Araki T, Fujiwara S, Motoyama K, Morioka T, Koyama H, Shoji T, Okuno Y, Nishizawa Y

    Diabetes care   27 ( 7 )   1756 - 8   2004.07( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.27.7.1756

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  • Increased arterial stiffening and thickening in the paretic lower limb in patients with hemiparesis. Reviewed

    Okabe R, Inaba M, Sakai S, Ishimura E, Moriguchi A, Shoji T, Nishizawa Y

    Clinical science (London, England : 1979)   106 ( 6 )   613 - 8   2004.06( ISSN:0143-5221

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1042/CS20030387

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  • [Arteriosclerosis in renal failure]. Invited Reviewed

    Shoji T, Nishizawa Y

    Nihon rinsho. Japanese journal of clinical medicine   62 Suppl 6   339 - 42   2004.06( ISSN:0047-1852

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    PubMed

  • FGF-23 in patients with end-stage renal disease on hemodialysis. Reviewed

    Imanishi Y, Inaba M, Nakatsuka K, Nagasue K, Okuno S, Yoshihara A, Miura M, Miyauchi A, Kobayashi K, Miki T, Shoji T, Ishimura E, Nishizawa Y

    Kidney international   65 ( 5 )   1943 - 6   2004.05( ISSN:0085-2538

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1523-1755.2004.00604.x

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  • Arterial stiffness in predialysis patients with uremia. Reviewed

    Shinohara K, Shoji T, Tsujimoto Y, Kimoto E, Tahara H, Koyama H, Emoto M, Ishimura E, Miki T, Tabata T, Nishizawa Y

    Kidney international   65 ( 3 )   936 - 43   2004.03( ISSN:0085-2538

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1523-1755.2004.00468.x

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  • Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment are useful indexes of insulin resistance in type 2 diabetic patients with wide range of fasting plasma glucose. Reviewed

    Yokoyama H, Emoto M, Fujiwara S, Motoyama K, Morioka T, Komatsu M, Tahara H, Koyama H, Shoji T, Inaba M, Nishizawa Y

    The Journal of clinical endocrinology and metabolism   89 ( 3 )   1481 - 4   2004.03( ISSN:0021-972X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/jc.2003-031374

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  • [Case Report No.138:One case of advanced renal hyperparathyroidim complicated with acute renal failure]. Invited Reviewed

    Lee E, Tahara H, Shoji T, Nagata M, Ueda M, Yamada S, Goto H, Inaba M, Nishizawa Y

    Clinical calcium   14 ( 3 )   462 - 5   2004.03( ISSN:0917-5857

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • Lower risk for cardiovascular mortality in oral 1alpha-hydroxy vitamin D3 users in a haemodialysis population. Reviewed

    Shoji T, Shinohara K, Kimoto E, Emoto M, Tahara H, Koyama H, Inaba M, Fukumoto S, Ishimura E, Miki T, Tabata T, Nishizawa Y

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   19 ( 1 )   179 - 84   2004.01( ISSN:0931-0509

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/gfg513

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  • Relationship between parathyroid gland size and responsiveness to maxacalcitol therapy in patients with secondary hyperparathyroidism. Reviewed

    Okuno S, Ishimura E, Kitatani K, Chou H, Nagasue K, Maekawa K, Izumotani T, Yamakawa T, Imanishi Y, Shoji T, Inaba M, Nishizawa Y

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   18 ( 12 )   2613 - 21   2003.12( ISSN:0931-0509

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/gfg451

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  • Inflammation and bone resorption as independent factors of accelerated arterial wall thickening in patients with rheumatoid arthritis. Reviewed

    Nagata-Sakurai M, Inaba M, Goto H, Kumeda Y, Furumitsu Y, Inui K, Koyama H, Emoto M, Ishimura E, Shoji T, Nishizawa Y

    Arthritis and rheumatism   48 ( 11 )   3061 - 7   2003.11( ISSN:0004-3591

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/art.11327

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  • Atherosclerosis in renal failure. Reviewed

    Shoji T, Nishizawa Y

    Internal medicine (Tokyo, Japan)   42 ( 11 )   1061 - 2   2003.11( ISSN:0918-2918

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2169/internalmedicine.42.1061

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  • Arterial wall stiffness is associated with peripheral circulation in patients with type 2 diabetes. Reviewed

    Kizu A, Koyama H, Tanaka S, Maeno T, Komatsu M, Fukumoto S, Emoto M, Shoji T, Inaba M, Shioi A, Miki T, Nishizawa Y

    Atherosclerosis   170 ( 1 )   87 - 91   2003.09( ISSN:0021-9150

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/s0021-9150(03)00237-5

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  • Platelet P-selectin expression is associated with atherosclerotic wall thickness in carotid artery in humans. Reviewed

    Koyama H, Maeno T, Fukumoto S, Shoji T, Yamane T, Yokoyama H, Emoto M, Shoji T, Tahara H, Inaba M, Hino M, Shioi A, Miki T, Nishizawa Y

    Circulation   108 ( 5 )   524 - 9   2003.08( ISSN:0009-7322

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1161/01.CIR.0000081765.88440.51

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  • Quantitative insulin sensitivity check index and the reciprocal index of homeostasis model assessment in normal range weight and moderately obese type 2 diabetic patients. Reviewed

    Yokoyama H, Emoto M, Fujiwara S, Motoyama K, Morioka T, Komatsu M, Tahara H, Shoji T, Okuno Y, Nishizawa Y

    Diabetes care   26 ( 8 )   2426 - 32   2003.08( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.26.8.2426

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  • Total synthesis and assignment of the double-bond position and absolute configuration of (-)-pyrinodemin A. Invited Reviewed

    Morimoto Y, Kitao S, Okita T, Shoji T

    Organic letters   5 ( 15 )   2611 - 4   2003.07( ISSN:1523-7060

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/ol034700v

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  • Association of muscle glycogen synthase polymorphism with insulin resistance in type 2 diabetic patients. Reviewed

    Motoyama K, Emoto M, Tahara H, Komatsu M, Shoji T, Inaba M, Nishizawa Y

    Metabolism: clinical and experimental   52 ( 7 )   895 - 9   2003.07( ISSN:0026-0495

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/s0026-0495(03)00075-1

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  • Factors affecting progression of renal failure in patients with type 2 diabetes. Reviewed

    Ueda H, Ishimura E, Shoji T, Emoto M, Morioka T, Matsumoto N, Fukumoto S, Miki T, Inaba M, Nishizawa Y

    Diabetes care   26 ( 5 )   1530 - 4   2003.05( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.26.5.1530

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  • Non-high-density lipoprotein cholesterol (non-HDL-C) as a predictor of cardiovascular mortality in patients with end-stage renal disease. Reviewed

    Nishizawa Y, Shoji T, Kakiya R, Tsujimoto Y, Tabata T, Ishimura E, Nakatani T, Miki T, Inaba M

    Kidney international. Supplement   ( 84 )   S117 - 20   2003.05( ISSN:0098-6577

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1046/j.1523-1755.63.s84.30.x

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  • Body fat mass in hemodialysis patients. Reviewed

    Ishimura E, Okuno S, Marukawa T, Katoh Y, Hiranaka T, Yamakawa T, Morii H, Kim M, Matsumoto N, Shoji T, Inaba M, Nakatani T, Nishizawa Y

    American journal of kidney diseases : the official journal of the National Kidney Foundation   41 ( 3 Suppl 1 )   S137 - 41   2003.03( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/ajkd.2003.50103

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  • Intrarenal hemodynamic changes after captopril test in patients with type 2 diabetes: a duplex Doppler sonography study. Reviewed

    Taniwaki H, Ishimura E, Kawagishi T, Matsumoto N, Hosoi M, Emoto M, Shoji T, Shoji S, Nakatani T, Inaba M, Nishizawa Y

    Diabetes care   26 ( 1 )   132 - 7   2003.01( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.26.1.132

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  • Pulse wave velocity in lower-limb arteries among diabetic patients with peripheral arterial disease. Reviewed

    Yokoyama H, Shoji T, Kimoto E, Shinohara K, Tanaka S, Koyama H, Emoto M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   10 ( 4 )   253 - 8   2003( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.10.253

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  • Decreased plasma adiponectin levels in young obese males. Reviewed

    Hara T, Fujiwara H, Shoji T, Mimura T, Nakao H, Fujimoto S

    Journal of atherosclerosis and thrombosis   10 ( 4 )   234 - 8   2003( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.10.234

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  • Arterial wall thickness is associated with insulin resistance in type 2 diabetic patients. Reviewed

    Fujiwara S, Emoto M, Komatsu M, Motoyama K, Morioka T, Koyama H, Shoji T, Inaba M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   10 ( 4 )   246 - 52   2003( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.10.246

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  • Preferential stiffening of central over peripheral arteries in type 2 diabetes.

    Diabetes   52   448 - 452   2003

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  • Intima-media thickness of carotid artery predicts cardiovascular mortality in hemodialysis patients.

    American Journal of Kidey Disease   41 ( Suppl )   S76-79   2003

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    Publishing type:Research paper (scientific journal)  

  • The association of antibodies against oxidized low-density lipoprotein with atherosclerosis in hemodialysis patients.

    Kidney International   Suppl   S128-130   2003

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    Publishing type:Research paper (scientific journal)  

  • Antibody to oxidized low-density lipoprotein and cardiovascular mortality in end-stage renal disease. Reviewed

    Shoji T, Fukumoto M, Kimoto E, Shinohara K, Emoto M, Tahara H, Koyama H, Ishimura E, Nakatani T, Miki T, Tsujimoto Y, Tabata T, Nishizawa Y

    Kidney international   62 ( 6 )   2230 - 7   2002.12( ISSN:0085-2538

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1046/j.1523-1755.2002.00692.x

    PubMed

  • Different risk factors for peripheral vascular calcification between diabetic and non-diabetic haemodialysis patients--importance of glycaemic control. Invited Reviewed

    Ishimura E, Okuno S, Kitatani K, Kim M, Shoji T, Nakatani T, Inaba M, Nishizawa Y

    Diabetologia   45 ( 10 )   1446 - 8   2002.10( ISSN:0012-186X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00125-002-0920-8

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  • ecNOS gene polymorphism is associated with endothelium-dependent vasodilation in Type 2 diabetes. Reviewed

    Komatsu M, Kawagishi T, Emoto M, Shoji T, Yamada A, Sato K, Hosoi M, Nishizawa Y

    American journal of physiology. Heart and circulatory physiology   283 ( 2 )   H557 - 61   2002.08( ISSN:0363-6135

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1152/ajpheart.00653.2001

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  • Insulin resistance as an independent predictor of cardiovascular mortality in patients with end-stage renal disease. Reviewed

    Shinohara K, Shoji T, Emoto M, Tahara H, Koyama H, Ishimura E, Miki T, Tabata T, Nishizawa Y

    Journal of the American Society of Nephrology : JASN   13 ( 7 )   1894 - 900   2002.07( ISSN:1046-6673

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/01.asn.0000019900.87535.43

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  • Advanced atherosclerosis in predialysis patients with chronic renal failure. Reviewed

    Shoji T, Emoto M, Tabata T, Kimoto E, Shinohara K, Maekawa K, Kawagishi T, Tahara H, Ishimura E, Nishizawa Y

    Kidney international   61 ( 6 )   2187 - 92   2002.06( ISSN:0085-2538

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1046/j.1523-1755.2002.00372.x

    PubMed

  • Increased thickness of the arterial intima-media detected by ultrasonography in patients with rheumatoid arthritis. Reviewed

    Kumeda Y, Inaba M, Goto H, Nagata M, Henmi Y, Furumitsu Y, Ishimura E, Inui K, Yutani Y, Miki T, Shoji T, Nishizawa Y

    Arthritis and rheumatism   46 ( 6 )   1489 - 97   2002.06( ISSN:0004-3591

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/art.10269

    PubMed

  • Impaired secretion of parathyroid hormone, but not refractoriness of osteoblast, is a major mechanism of low bone turnover in hemodialyzed patients with diabetes mellitus. Reviewed

    Inaba M, Nagasue K, Okuno S, Ueda M, Kumeda Y, Imanishi Y, Shoji T, Ishimura E, Ohta T, Nakatani T, Kim M, Nishizawa Y

    American journal of kidney diseases : the official journal of the National Kidney Foundation   39 ( 6 )   1261 - 9   2002.06( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/ajkd.2002.33400

    PubMed

  • Impact of Prol2Ala variant in the peroxisome proliferator-activated receptor (PPAR) gamma2 on obesity and insulin resistance in Japanese Type 2 diabetic and healthy subjects. Reviewed

    Kawasaki I, Tahara H, Emoto M, Shoji T, Shioji A, Okuno Y, Inaba M, Nishizawa Y

    Osaka city medical journal   48 ( 1 )   23 - 8   2002.06( ISSN:0030-6096

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • The 807T allele in alpha2 integrin is protective against atherosclerotic arterial wall thickening and the occurrence of plaque in patients with type 2 diabetes. Reviewed

    Maeno T, Koyama H, Tahara H, Komatsu M, Emoto M, Shoji T, Inaba M, Miki T, Okuno Y, Nishizawa Y

    Diabetes   51 ( 5 )   1523 - 8   2002.05( ISSN:0012-1797

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diabetes.51.5.1523

    PubMed

  • [Sibling cases of nephritis resembling membranoproliferative glomerulonephritis]. Invited Reviewed

    Ueda H, Isimura E, Okuno S, Maekawa K, Izumotani T, Kim M, Matsumoto N, Fukumoto S, Imanishi Y, Emoto M, Shoji T, Wanibuchi H, Inaba M, Nishizawa Y

    Nihon Jinzo Gakkai shi   44 ( 4 )   420 - 6   2002.05( ISSN:0385-2385

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • Smoking and proteinuria impair vasodilatory response of intrarenal arteries to nitroglycerine in patients with type 2 diabetes mellitus. Reviewed

    Matsumoto N, Ishimura E, Taniwaki H, Emoto M, Shoji T, Kawagishi T, Inaba M, Nishizawa Y

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   17 ( 4 )   608 - 13   2002.04( ISSN:0931-0509

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/17.4.608

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  • Relationship between TaqIB cholesteryl ester transfer protein gene polymorphism and macrovascular complications in Japanese patients with type 2 diabetes. Reviewed

    Kawasaki I, Tahara H, Emoto M, Shoji T, Nishizawa Y

    Diabetes   51 ( 3 )   871 - 4   2002.03( ISSN:0012-1797

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diabetes.51.3.871

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  • Effect of diabetes on uremic dyslipidemia. Reviewed

    Kimoto E, Shoji T, Emoto M, Miki T, Tabata T, Okuno Y, Ishimura E, Inaba M, Nishizawa Y

    Journal of atherosclerosis and thrombosis   9 ( 6 )   305 - 13   2002( ISSN:1340-3478

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5551/jat.9.305

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  • [Intravenous pamidronate delivery to a case with multiple bone metastasis of breast cancer]. Invited Reviewed

    Yokoyama H, Nakatsuka K, Shoji T, Kawasaki I, Inaba M, Nishizawa Y

    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics   38 ( 6 )   812 - 5   2001.11( ISSN:0300-9173

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3143/geriatrics.38.812

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  • HOMA index to assess insulin resistance in renal failure patients. Invited Reviewed

    Shoji T, Emoto M, Nishizawa Y

    Nephron   89 ( 3 )   348 - 9   2001.11( ISSN:1660-8151

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000046098

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  • Atherogenic lipoproteins in end-stage renal disease. Invited Reviewed

    Shoji T, Ishimura E, Inaba M, Tabata T, Nishizawa Y

    American journal of kidney diseases : the official journal of the National Kidney Foundation   38 ( 4 Suppl 1 )   S30 - 3   2001.10( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/ajkd.2001.27393

    PubMed

  • Renal insufficiency accelerates atherosclerosis in patients with type 2 diabetes mellitus. Invited Reviewed

    Ishimura E, Shoji T, Emoto M, Motoyama K, Shinohara K, Matsumoto N, Taniwaki H, Inaba M, Nishizawa Y

    American journal of kidney diseases : the official journal of the National Kidney Foundation   38 ( 4 Suppl 1 )   S186 - 90   2001.10( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/ajkd.2001.27440

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  • Paradox of risk factors for cardiovascular mortality in uremia: is a higher cholesterol level better for atherosclerosis in uremia? Invited Reviewed

    Nishizawa Y, Shoji T, Ishimura E, Inaba M, Morii H

    American journal of kidney diseases : the official journal of the National Kidney Foundation   38 ( 4 Suppl 1 )   S4 - 7   2001.10( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/ajkd.2001.27380

    PubMed

  • [Multiple risk factor syndrome]. Invited Reviewed

    Shoji T, Nishizawa Y

    Nihon rinsho. Japanese journal of clinical medicine   59 Suppl 3   130 - 5   2001.03( ISSN:0047-1852

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • Impact of insulin resistance and nephropathy on homocysteine in type 2 diabetes. Invited Reviewed

    Emoto M, Kanda H, Shoji T, Kawagishi T, Komatsu M, Mori K, Tahara H, Ishimura E, Inaba M, Okuno Y, Nishizawa Y

    Diabetes care   24 ( 3 )   533 - 8   2001.03( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.24.3.533

    PubMed

  • Femoral artery wall thickness and stiffness in evaluation of peripheral vascular disease in type 2 diabetes mellitus

    Atherosclerosis   158 ( 1 )   207 - 214   2001

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    Publishing type:Research paper (scientific journal)  

  • Effect of insulin resistance on serum paraoxonase activity in a nondiabetic population

    Metabolism   50 ( 7 )   805 - 811   2001

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    Publishing type:Research paper (scientific journal)  

  • Atherogenic lipoprotein changes in diabetic nephropathy

    Atherosclerosis   156 ( 2 )   425 - 433   2001

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    Publishing type:Research paper (scientific journal)  

  • Glycemic control is a predictor of survival for diabetic patients on hemodialysis

    Diabetes Care   24 ( 5 )   909 - 913   2001

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    Publishing type:Research paper (scientific journal)  

  • Increasing body fat mass in the first year of hemodialysis

    Journal of American Society of Nephrology   12 ( 9 )   1921 - 1926   2001

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    Publishing type:Research paper (scientific journal)  

  • Antibodies against oxidized LDL and carotid artery intima-media thickness in a healthy population

    Arteriosclerosis, Thrombosis, and Vascular Biology   20 ( 3 )   703 - 707   2000

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    Publishing type:Research paper (scientific journal)  

  • Additive impacts of diabetes and renal failure on carotid atherosclerosis

    Atherosclerosis   153 ( 1 )   257 - 258   2000

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    Publishing type:Research paper (scientific journal)  

  • Relationship between urinary albumin excretion and glomerular filtration rate in normotensive, nonproteinuric patients with type 2 diabetes mellitus

    Nephron   86 ( 1 )   36 - 43   2000

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    Publishing type:Research paper (scientific journal)  

  • Diabetes mellitus worsens intrarenal hemodynamic abnormalities in nondialyzed patients with chronic renal failure

    Nephron   86 ( 1 )   44 - 51   2000

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    Publishing type:Research paper (scientific journal)  

  • Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects

    Atherosclerosis   148   171 - 177   2000

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    Publishing type:Research paper (scientific journal)  

  • Association of ACE gene polymorphism with arterial stiffness in patients with type 2 diabetes. Invited Reviewed

    Taniwaki H, Kawagishi T, Emoto M, Shoji T, Hosoi M, Kogawa K, Nishizawa Y, Morii H

    Diabetes care   22 ( 11 )   1858 - 64   1999.11( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.22.11.1858

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  • Leptin in peritoneal dialysate from continuous ambulatory peritoneal dialysis patients. Invited Reviewed

    Tsujimoto Y, Shoji T, Tabata T, Morita A, Emoto M, Nishizawa Y, Morii H

    American journal of kidney diseases : the official journal of the National Kidney Foundation   34 ( 5 )   832 - 8   1999.11( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/S0272-6386(99)70039-9

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  • Correlation between the intima-media thickness of the carotid artery and aortic pulse-wave velocity in patients with type 2 diabetes. Vessel wall properties in type 2 diabetes. Invited Reviewed

    Taniwaki H, Kawagishi T, Emoto M, Shoji T, Kanda H, Maekawa K, Nishizawa Y, Morii H

    Diabetes care   22 ( 11 )   1851 - 7   1999.11( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.22.11.1851

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  • Effects of lipid-lowering drugs on intermediate-density lipoprotein in uremic patients. Invited Reviewed

    Nishizawa Y, Shoji T, Tabata T, Inoue T, Morii H

    Kidney international. Supplement   71   S134 - 6   1999.07( ISSN:0098-6577

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1046/j.1523-1755.1999.07133.x

    PubMed

  • Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Invited Reviewed

    Emoto M, Nishizawa Y, Maekawa K, Hiura Y, Kanda H, Kawagishi T, Shoji T, Okuno Y, Morii H

    Diabetes care   22 ( 5 )   818 - 22   1999.05( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.22.5.818

    PubMed

  • Stiffness indexes beta of the common carotid and femoral arteries are associated with insulin resistance in NIDDM. Invited Reviewed

    Emoto M, Nishizawa Y, Kawagishi T, Maekawa K, Hiura Y, Kanda H, Izumotani K, Shoji T, Ishimura E, Inaba M, Okuno Y, Morii H

    Diabetes care   21 ( 7 )   1178 - 82   1998.07( ISSN:0149-5992

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diacare.21.7.1178

    PubMed

  • Plasma leptin level and its relationship with body composition in hemodialysis patients. Invited Reviewed

    Nishizawa Y, Shoji T, Tanaka S, Yamashita M, Morita A, Emoto M, Tabata T, Inoue T, Morii H

    American journal of kidney diseases : the official journal of the National Kidney Foundation   31 ( 4 )   655 - 61   1998.04( ISSN:0272-6386

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/ajkd.1998.v31.pm9531182

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  • Atherosclerosis in uremia: possible roles of hyperparathyroidism and intermediate density lipoprotein accumulation. Invited Reviewed

    Nishizawa Y, Shoji T, Kawagishi T, Morii H

    Kidney international. Supplement   62   S90 - 2   1997.11( ISSN:0098-6577

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    Publishing type:Research paper (scientific journal)  

    PubMed

  • Renal function and insulin resistance as determinants of plasma leptin levels in patients with NIDDM. Invited Reviewed

    Shoji T, Nishizawa Y, Emoto M, Maekawa K, Hiura Y, Tanaka S, Kawagishi T, Okuno Y, Morii H

    Diabetologia   40 ( 6 )   676 - 9   1997.06( ISSN:0012-186X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s001250050733

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  • Effect of polymorphism of apolipoprotein E and angiotensin-converting enzyme genes on arterial wall thickness. Invited Reviewed

    Kogawa K, Nishizawa Y, Hosoi M, Kawagishi T, Maekawa K, Shoji T, Okuno Y, Morii H

    Diabetes   46 ( 4 )   682 - 7   1997.04( ISSN:0012-1797

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2337/diab.46.4.682

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  • High-resolution B-mode ultrasonography in evaluation of atherosclerosis in uremia. Invited Reviewed

    Kawagishi T, Nishizawa Y, Konishi T, Kawasaki K, Emoto M, Shoji T, Tabata T, Inoue T, Morii H

    Kidney international   48 ( 3 )   820 - 6   1995.09( ISSN:0085-2538

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/ki.1995.356

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  • Hypertriglyceridemia and lowered apolipoprotein C-II/C-III ratio in uremia: effect of a fibric acid, clinofibrate. Invited Reviewed

    Nishizawa Y, Shoji T, Nishitani H, Yamakawa M, Konishi T, Kawasaki K, Morii H

    Kidney international   44 ( 6 )   1352 - 9   1993.12( ISSN:0085-2538

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/ki.1993.388

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  • High serum lipoprotein(a) concentrations in uremic patients treated with continuous ambulatory peritoneal dialysis. Invited Reviewed

    Shoji T, Nishizawa Y, Nishitani H, Yamakawa M, Morii H

    Clinical nephrology   38 ( 5 )   271 - 6   1992.11( ISSN:0301-0430

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    Publishing type:Research paper (scientific journal)  

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  • Altered calcium homeostasis accompanying changes of regional bone mineral during a very-low-calorie diet. Invited Reviewed

    Nishizawa Y, Koyama H, Shoji T, Tahara H, Hagiwara S, Aratani H, Nakatsuka K, Miki T, Morii H

    The American journal of clinical nutrition   56 ( 1 Suppl )   265S - 267S   1992.07( ISSN:0002-9165

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ajcn/56.1.265S

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  • High-density-lipoprotein metabolism during a very-low-calorie diet. Invited Reviewed

    Shoji T, Nishizawa Y, Koyama H, Hagiwara S, Aratani H, Sasao K, Kishimoto H, Tanishita H, Morii H

    The American journal of clinical nutrition   56 ( 1 Suppl )   297S - 298S   1992.07( ISSN:0002-9165

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ajcn/56.1.297S

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  • Transport of 1,5-anhydro-D-glucitol into human polymorphonuclear leukocytes. Invited Reviewed

    Okuno Y, Nishizawa Y, Kawagishi T, Sekiya K, Shoji T, Morii H

    Journal of biochemistry   111 ( 1 )   99 - 102   1992.01( ISSN:0021-924X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/oxfordjournals.jbchem.a123726

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  • Uremic serum contains humoral factor(s) larger than fifty kilodaltons which suppresses endothelin production in cultured endothelial cells. Invited Reviewed

    Koyama H, Tahara H, Shoji T, Nishizawa Y, Inaba M, Otani S, Yanagisawa M, Ishiguro Y, Takanashi N, Morii H

    Contributions to nephrology   90   111 - 5   1991( ISSN:0302-5144

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000420132

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Books and Other Publications

  • J-DAVID試験から学ぶ腎臓・透析領域における臨床試験の軌跡

    ( Role: Edit)

    メディカ出版  2022.06 

  • CKD-MBD:日本からのエビデンス発信 High-Impact Clinical Researches and Trials

    ( Role: Edit)

    メディカ出版  2022.06 

MISC

  • Body fat measurement in chronic kidney diease: implications in research and clinical practice.

    Current Opinion in Nephrology and Hypertennsion   16 ( 6 )   572 - 576   2007

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Plasma lipoprotein abnormalities in hemodialysis patients--clinical implications and therapeutic guidelines.

    Therapeutic Apheresis and Dialysis   10   305 - 315   2006

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Does paricalcitol reduce proteinuria in patients with chronic kidney disease?

    Nature Clinical Practice Nephrology   2   352 - 353   2006

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Body composition and cardiovascular risk in hemodialysis patients.

    Journal of Renal Nutrition   16   241 - 244   2006

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Chronic kidney disease as a metabolic syndrome with malnutrition--need for strict control of risk factors.

    Intern Medicine   44   179 - 187   2005

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Molecular forms of adiponectin in uraemic plasma.

    Nephrology, Dialysis, and Transplantation   19   1937 - 1938   2004

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Single Work  

  • Multiple risk factor syndrome

    Nippon Rinsho   59 Suppl 3   130 - 135   2001

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    Publishing type:Article, review, commentary, editorial, etc. (other)  

  • Plasma leptin level and its relatiornship with body composition in hemodialysis patients.

    American Journal of Kidney Diseases   31 ( 4 )   655   1998

  • Intermediate-density lipoprotein as an independent risk factor for aortic atherosclerosis in hemodialysis patients.

    Journal of the American Society of Nephrology   9 ( 7 )   1277   1998

  • Atherogenic lipoprotein changes in the absence of hyperlipidemia in patients with chronic renal failure treated by hemodialysis.

    Atherosclerosis   131 ( 2 )   229   1997

  • Renal function and insulin resistance asdeterminants of plasma leptin leuels in patients with NIDDM.

    Diabetologia   40 ( 6 )   676   1997

  • Reduction of intermediate density lipoprotein by pravastatin in hemo- and peritoneal dialysis patients

    Clinical Nephrology   43 ( 4 )   268   1995

  • Hypertriglyceridemia and lowered apolipoprotein CII/CIII ratio in uremia : Effects of a fibric acid, clinofibrate.

    Kidney International   44   1352   1993

  • Impaired metabolism of high density lipoprotein in uremic patients

    Kidney International   41 ( 6 )   1653   1992

  • Molecular studies on primary LPL deficiency

    Journal of Clinical Investigation   89   581   1992

  • High Serum lipoprotein(a) Concentrations in uremic protients treated with continuous ambulatory peritoneal dialysis

    Clinical Nephrology   38 ( 5 )   271   1992

  • Roles of hypoalbuminemia and lipoprotein lipase on hyperlipoproteinemia in continuous ambulatory peritoneal dialysis

    Metabolism   40 ( 10 )   1002   1991

  • Lipoprotein metabolism in normolipidemic obese Women during very low calorie diet : Changes in high density lipoprotein

    Journal of Nutritional Science and Vitaminology   37 ( Suppl )   S57   1991

  • Obesity as a determinant of regional bone mineral density

    Journal of Nutritional Science and Vitaminology   37 ( Suppl )   S65   1991

  • Decreased albuminuria by pravastatin in hyperlipidemic diabetics

    Nephron   59   664   1991

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Presentations

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Collaborative research (seeds) keywords

  • Annual changes in cognitive function in patients undergoing hemodialysis

    Category:Life Science 

Outline of collaborative research (seeds)

  • lipoprotein abnormalities

    とくになし

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    Application fields / methods etc:Analysis of pathogenesis and evaluation of therapy

    Core knowledge, technology, information etc:Lipoprotein analysis

    Atherogenic changes of lipoproteins

  • 透析患者の認知機能

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    Type of research exchange:Joint research

  • 血清石灰化傾向(T50)

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    Type of research exchange:Joint research

Grant-in-Aid for Scientific Research

  • Phosphate toxicity as a factor which promotes aging in kidney failure patients undergoing hemodialysis

    Grant-in-Aid for Scientific Research(C)  2024

  • 慢性腎臓病におけるCPP病原体説の臨床的検証

    Grant-in-Aid for Scientific Research(C)  2014.04

Outline of education staff

  • dyslipidemia

Charge of on-campus class subject

  • Vascular Medicine Research Methods

    2024     Graduate school

  • Vascular Medicine Overview

    2024     Graduate school

  • Basic Course of Geriatrics

    2024     Graduate school

  • Geriatrics

    2024     Graduate school

Social Activities ⇒ Link to the list of Social Activities

  • 第54回日本動脈硬化学会総会・学術集会 市民公開講座「健康長寿を延ばすために!~今でしょ!!心臓病と脳卒中の予防と対策~

    Role(s): Lecturer

    Type: Lecture

    京王プラザホテル(東京)  2013.07

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    Audience: General public

    Number of participants:300(人)