Updated on 2023/10/01

写真a

 
SUEHIRO Koichi
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Associate Professor
School of Medicine Department of Medical Science
Title
Associate Professor
Affiliation
Institute of Medicine

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Associate Professor  2023.10 - Now

  • Graduate School of Medicine Department of Clinical Medical Science 

    Lecturer  2022.04 - 2023.09

  • School of Medicine Department of Medical Science 

    Associate Professor  2023.10 - Now

  • School of Medicine Department of Medical Science 

    Lecturer  2022.04 - 2023.09

Degree

  • Doctor (Medicine) （ Osaka City University ）

Research Areas

  • Life Science / Anesthesiology

Research Interests

  • Hemodynamic monitoring

Research subject summary

  • Hemodynamic monitoring in the perioperative period

Research Career

  • Hemodynamic management in the perioperative period

    Individual

    2015.04 - Now 

Professional Memberships

  • Japanese Society of Anesthesiologists

      Domestic

  • American Society of Anesthesiologists

      Domestic

Awards

  • American Society of Anesthesiologists annual meeting, Best Abstract Award: Clinical Science

    2019.10  

  • American Society of Anesthesiologists annual meeting, Best Abstract Award: Clinical Science

    2019.10  

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    Country：United States

  • 日本麻酔科学会第66回学術集会 最優秀演題

    2019.05  

  • 日本麻酔科学会第66回学術集会 最優秀演題

    2019.05  

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    Country：Japan

  • 南部陽一郎記念若手奨励賞

    2017.11  

  • 南部陽一郎記念若手奨励賞

    2017.11  

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    Country：Japan

  • 日本心臓血管麻酔学会　藤田昌雄賞

    2017.09  

  • 日本心臓血管麻酔学会 優秀教育講演賞

    末廣 浩一

    2017.09  

  • 日本心臓血管麻酔学会 藤田昌雄賞

    末廣 浩一

    2017.09  

  • 日本麻酔学会若手奨励賞

    末廣 浩一

    2014.05  

  • 日本麻酔科学会若手奨励賞

    2014.03  

  • 大阪市医学会賞

    2014.03  

  • 大阪市医学会賞

    末廣 浩一

    2014.03  

  • 日本麻酔科学会若手奨励賞

    2014.03  

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    Country：Japan

▼display all

Job Career (off-campus)

  • カリフォルニア大学アーバイン校麻酔科   リサーチフェロー

    2014.04 - 2015.03

  • 大阪市立総合医療センター   救命救急センター   シニアレジデント

    2010.04 - 2011.03

  • 大阪市立総合医療センター   麻酔科   前期研究医

    2007.04 - 2010.03

  • 大阪市立総合医療センター   前期研修医

    2005.04 - 2007.03

Education

  • Nara Medical University     Graduated/Completed

  • Osaka City University   Doctor's Course   Graduated/Completed

Papers

  • Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury.

    Kimura A, Suehiro K, Mukai A, Fujimoto Y, Funao T, Yamada T, Mori T

    The Journal of thoracic and cardiovascular surgery   164 ( 6 )   e269 - e283   2022.12（ ISSN:0022-5223 ）

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  • Recruitment maneuverによる血行動態変化率は分離肺換気下における輸液反応性の指標として有効である

    木村 文, 末廣 浩一, 重里 尚, 藤本 陽平, 吉田 寿子, 田中 克明, 森 隆, 西川 精宣

    麻酔   71 ( 増刊 )   S171 - S178   2022.11（ ISSN:0021-4892 ）

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    Recruitment maneuver(RM)による1回心拍出量(SV)変化量および平均動脈圧(MAP)変化量が一側肺換気(OLV)中における輸液反応性の指標として有用であるかどうか検討した。ビデオ支援胸腔鏡手術による食道切除術または肺切除術のためにOLVを行う症例30例を対象とした。ΔSV RMはSV-responderの方がSV-non-responderより有意に大きく、ΔMAP RMはBP-non-responderに比べてBP-responderで有意に高値であった。SV-responderを判別するΔSV RMのAUCは0.84であり、1回拍出量変動(SVV)と脈圧変動(PPV)はともに輸液反応性を有効に予測できなかった。SV-responderのカットオフ値は-23.7%、感度は76.5%、特異度は84.6%であった。BP-responderについては、ΔMAP RMのAUCは0.80であり、SVVとPPVはともに輸液反応性を予測できなかった。ΔMAP RMのカットオフ値は-17.3%、感度は75.0%、特異度は77.8%であった。RMによるSVとBPの変化率は輸液負荷後のSVの増加を予測することができた。従来から輸液反応性の予測に用いられてきたSVVとPPVの予測能力は低いことが示された。

  • Assessing fluid responsiveness during spontaneous breathing.

    Suehiro K

    Journal of anesthesia   36 ( 5 )   579 - 582   2022.10（ ISSN:0913-8668 ）

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  • Changes in corrected carotid flow time induced by recruitment maneuver predict fluid responsiveness in patients undergoing general anesthesia.

    Kimura A, Suehiro K, Juri T, Tanaka K, Mori T

    Journal of clinical monitoring and computing   36 ( 4 )   1069 - 1077   2022.08（ ISSN:1387-1307 ）

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  • Postoperative Pulmonary Complications After Cardiac Surgery: The VENICE International Cohort Study.

    Fischer MO, Brotons F, Briant AR, Suehiro K, Gozdzik W, Sponholz C, Kirkeby-Garstad I, Joosten A, Nigro Neto C, Kunstyr J, Parienti JJ, Abou-Arab O, Ouattara A, VENICE study group

    Journal of cardiothoracic and vascular anesthesia   36 ( 8 Pt A )   2344 - 2351   2022.08（ ISSN:1053-0770 ）

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  • Non-invasive continuous blood pressure monitoring using the ClearSight system for pregnant women at high risks of post-partum hemorrhage: comparison with invasive blood pressure monitoring during cesarean section.

    Misugi T, Juri T, Suehiro K, Kitada K, Kurihara Y, Tahara M, Hamuro A, Nakano A, Koyama M, Mori T, Tachibana D

    Obstetrics & gynecology science   65 ( 4 )   325 - 334   2022.07（ ISSN:2287-8572 ）

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  • Validation of Continuous Noninvasive Blood Pressure Monitoring Using Error Grid Analysis.

    Juri T, Suehiro K, Kanematsu R, Takahashi K, Fujimoto Y, Tanaka K, Mori T

    Anesthesia and analgesia   134 ( 4 )   773 - 780   2022.04（ ISSN:0003-2999 ）

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  • Changes in stroke volume induced by lung recruitment maneuver can predict fluid responsiveness during intraoperative lung-protective ventilation in prone position.

    Watanabe R, Suehiro K, Mukai A, Tanaka K, Yamada T, Mori T, Nishikawa K

    BMC anesthesiology   21 ( 1 )   303   2021.12

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  • Participation of the descending noradrenergic inhibitory system in the anti-hyperalgesic effect of acetaminophen in a rat model of inflammation.

    Juri T, Fujimoto Y, Suehiro K, Nishikawa K, Mori T

    Life sciences   286   120030   2021.12（ ISSN:0024-3205 ）

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  • Error grid analysis for risk management in the difference between invasive and noninvasive blood pressure measurements Reviewed

    Juri Takashi, Suehiro Koichi, Uchimoto Akihiro, Go Hirofumi, Fujimoto Yohei, Mori Takashi, Nishikawa Kiyonobu

    JOURNAL OF ANESTHESIA   35 ( 2 )   189 - 196   2021.04（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    PURPOSE: Invasive arterial blood pressure (IAP) and noninvasive blood pressure (NIBP) measurements are both common methods. Recently, a new method of error grid analysis was proposed to compare blood pressure obtained using two measurement methods. This study aimed to compare IAP and NIBP measurements using the error grid analysis and investigate potential confounding factors affecting the discrepancies between IAP and NIBP. METHODS: Adult patients who underwent general anesthesia in the supine position with both IAP and NIBP measurements were retrospectively investigated. The error grid analyses were performed to compare IAP and NIBP. In the error grid analysis, the clinical relevance of the discrepancies between IAP and NIBP was evaluated and classified into five zones from no risk (A) to dangerous risk (E). RESULTS: Overall, data of 1934 IAP/NIBP measurement pairs from 100 patients were collected. The error grid analysis revealed that the proportions of zones A-E for systolic blood pressure were 96.4%, 3.5%, 0.05%, 0%, and 0%, respectively. In contrast, the proportions for mean blood pressure were 82.5%, 16.7%, 0.8%, 0%, and 0%, respectively. The multiple regression analysis revealed that continuous phenylephrine administration (p = 0.016) and age (p = 0.044) were the significant factors of an increased clinical risk of the differences in mean blood pressure. CONCLUSIONS: The error grid analysis indicated that the differences between IAP and NIBP for mean blood pressure were not clinically acceptable and had the risk of leading to unnecessary treatments. Continuous phenylephrine administration and age were the significant factors of an increased clinical risk of the discrepancies between IAP and NIBP.

    DOI： 10.1007/s00540-020-02893-6

    PubMed

  • Preoperative assessment for scheduling surgery during the coronavirus disease pandemic Reviewed

    Suehiro Koichi

    JOURNAL OF ANESTHESIA   2021.01（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)   Kind of work：Single Work  

    On Mar 11, 2020, the World Health Organization declared coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a pandemic. Because COVID-19 has a pre-symptomatic period of up to 2 weeks, SARS-CoV-2 infection has continued to spread. Some individuals with SARS-CoV-2 infection have a severe clinical course, while most individuals have mild or moderate symptoms. Because SARS-CoV-2 is transmitted via droplets and secretions, anesthesiologists have higher risks of infection, especially during airway management. Therefore, general anesthesia requiring airway management can be a challenging procedure for anesthesiologists. During the pandemic, many elective surgeries have been postponed or cancelled in most affected countries. Recently, the number of elective surgeries is gradually recovering from the effect of the COVID-19 pandemic, and hence, safe clinical practice and protocols to prevent SARS-CoV-2 transmission to medical staff should be established. This mini-review focuses on the preoperative assessment and decision with regard to scheduling surgery in elective and emergency cases during the COVID-19 pandemic. A standardized questionnaire and algorithm regarding COVID-19 should be used to assess surgical patients preoperatively as it increases the reproducibility and accuracy of the decision whether to proceed with surgery.

    DOI： 10.1007/s00540-021-02896-x

    PubMed

  • Hemodynamic Changes via the Lung Recruitment Maneuver Can Predict Fluid Responsiveness in Stroke Volume and Arterial Pressure During One-Lung Ventilation. Reviewed

    Aya Kimura, Koichi Suehiro, Takashi Juri, Yohei Fujimoto, Hisako Yoshida, Katsuaki Tanaka, Takashi Mori, Kiyonobu Nishikawa

    Anesthesia and analgesia   2021.01

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    Publishing type：Research paper (scientific journal)  

    BACKGROUND: We aimed to evaluate the ability of lung recruitment maneuver-induced hemodynamic changes to predict fluid responsiveness in patients undergoing lung-protective ventilation during one-lung ventilation (OLV). METHODS: Thirty patients undergoing thoracic surgery with OLV (tidal volume: 6 mL/kg of ideal body weight and positive end-expiratory pressure: 5 cm H2O) were enrolled. The study protocol began 30 minutes after starting OLV. Simultaneous recordings were performed for hemodynamic variables of heart rate, mean arterial pressure (MAP), stroke volume (SV), pulse pressure variation (PPV), and stroke volume variation (SVV) were recorded at 4 time points: before recruitment maneuver (continuous airway pressure: 30 cm H2O for 30 seconds), at the end of recruitment maneuver, and before and after volume loading (250 mL over 10 minutes). Patients were recognized as fluid responders if the increase in SV or MAP was >10%. Receiver operating characteristic curves for percent decrease in SV and MAP by recruitment maneuver (ΔSVRM and ΔMAPRM, respectively) were generated to evaluate the ability to discriminate fluid responders from nonresponders. The gray-zone approach was applied for ΔSVRM and ΔMAPRM. RESULTS: Of 30 patients, there were 17 SV-responders (57%) and 12 blood pressure (BP)-responders (40%). Area under the curve (AUC) for ΔSVRM to discriminate SV-responders from nonresponders was 0.84 (95% confidence interval [CI], 0.67-0.95; P < .001). The best threshold for ΔSVRM to discriminate the SV-responders was -23.7% (95% CI, -41.2 to -17.8; sensitivity, 76.5% [95% CI, 50.1-93.2]; specificity, 84.6% [95% CI, 54.6-98.1]). For BP-responders, AUC for ΔMAPRM was 0.80 (95% CI, 0.61-0.92, P < .001). The best threshold for ΔMAPRM was -17.3% (95% CI, -23.9 to -5.1; sensitivity, 75.0% [95% CI, 42.8-94.5]; specificity, 77.8% [95% CI, 52.4-93.6]). With the gray-zone approach, the inconclusive range of ΔSVRM for SV-responders was -40.1% to -13.8% including 13 (43%) patients, and that of ΔMAPRM was -23.9% to -5.1%, which included 16 (53%) patients. CONCLUSIONS: ΔSVRM and ΔMAPRM could predict hemodynamic responses after volume expansion during OLV.

    DOI： 10.1213/ANE.0000000000005375

    PubMed

  • Impact of intraoperative goal-directed fluid therapy on major morbidity and mortality after transthoracic oesophagectomy: a multicentre, randomised controlled trial Reviewed

    Mukai Akira, Suehiro Koichi, Watanabe Ryota, Juri Takashi, Hayashi Yasue, Tanaka Katsuaki, Fujii Takashi, Ohira Naoko, Oda Yutaka, Okutani Ryu, Nishikawa Kiyonobu

    BRITISH JOURNAL OF ANAESTHESIA   125 ( 6 )   953 - 961   2020.12（ ISSN:0007-0912 ）

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    Publishing type：Research paper (scientific journal)  

    BACKGROUND: Transthoracic oesophagectomy is associated with major morbidity and mortality, which may be reduced by goal-directed therapy (GDT). The aim of this multicentre, RCT was to evaluate the impact of intraoperative GDT on major morbidity and mortality in patients undergoing transthoracic oesophagectomy. METHODS: Adult patients undergoing transthoracic oesophagectomy were randomised to receive either minimally invasive intraoperative GDT (stroke volume variation <8%, plus systolic BP maintained >90 mm Hg by pressors as necessary) or haemodynamic management left to the discretion of attending senior anaesthetists (control group; systolic BP >90 mm Hg alone). The primary outcome was the incidence of death or major complications (reoperation for bleeding, anastomotic leakage, pneumonia, reintubation, >48 h ventilation). A Cox proportional hazard model was used to examine whether the effects of GDT on morbidity and mortality were independent of other potential confounders. RESULTS: A total of 232 patients (80.6% male; age range: 36-83 yr) were randomised to either GDT (n=115) or to the control group (n=117). After surgery, major morbidity and mortality were less frequent in 22/115 (19.1%) subjects randomised to GDT, compared with 41/117 (35.0%) subjects assigned to the control group {absolute risk reduction: 15.9% (95% confidence interval [CI]: 4.7-27.2%); P=0.006}. GDT was also associated with fewer episodes of atrial fibrillation (odds ratio [OR]: 0.18 [95% CI: 0.05-0.65]), respiratory failure (OR: 0.27 [95% CI: 0.09-0.83]), use of mini-tracheotomy (OR: 0.29 [95% CI: 0.10-0.81]), and readmission to ICU (OR: 0.09 [95% CI: 0.01-0.67]). GDT was independently associated with morbidity and mortality (hazard ratio: 0.51 [95% CI: 0.30-0.87]; P=0.013). CONCLUSIONS: Intraoperative GDT may reduce major morbidity and mortality, and shorten hospital stay, after transthoracic oesophagectomy. CLINICAL TRIAL REGISTRATION: UMIN000018705.

    DOI： 10.1016/j.bja.2020.08.060

    PubMed

  • Effect of Systemic Vascular Resistance on the Reliability of Noninvasive Hemodynamic Monitoring in Cardiac Surgery. Reviewed

    Akira Mukai, Koichi Suehiro, Aya Kimura, Katsuaki Tanaka, Tokuhiro Yamada, Takashi Mori, Kiyonobu Nishikawa

    Journal of cardiothoracic and vascular anesthesia   2020.11

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    Publishing type：Research paper (scientific journal)  

    OBJECTIVE: To assess the effect of systemic vascular resistance (SVR) on the reliability of the ClearSight system (Edwards Lifesciences, Irvine, CA) for measuring blood pressure (BP) and cardiac output (CO). DESIGN: Observational study. SETTING: University hospital. PARTICIPANTS: Twenty-five patients undergoing cardiac surgery. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: BP, measured using ClearSight and an arterial line, and CO, measured using ClearSight and a pulmonary artery catheter, were recorded before (T1) and two minutes after phenylephrine or ephedrine administration. Bland-Altman analysis was used to compare BP and CO measurements at T1. A polar plot was used to assess trending abilities. Patients were divided into the following three groups according to the SVR index (SVRI) at T1: low (<1,200 dyne s/cm5/m2), normal (1,200-25,00 dyne s/cm5/m2), and high (>2,500 dyne s/cm5/m2). The bias in BP and CO was -4.8 ± 8.9 mmHg and 0.10 ± 0.81 L/min, respectively, which was correlated significantly with SVRI (p < 0.05). The percentage error in CO was 40.6%, which was lower in the normal SVRI group (33.3%) than the low and high groups (46.3% and 47.7%, respectively). The angular concordance rate was 96.3% and 95.4% for BP and 87.0% and 92.5% for CO after phenylephrine and ephedrine administration, respectively. There was a low tracking ability for CO changes after phenylephrine administration in the low-SVRI group (angular concordance rate 33.3%). CONCLUSION: The ClearSight system showed an acceptable accuracy in measuring BP and tracking BP changes in various SVR states; however, the accuracy of CO measurement and its trending ability in various SVR states was poor.

    DOI： 10.1053/j.jvca.2020.11.011

    PubMed

  • Protective effects of remote ischemic preconditioning against spinal cord ischemia-reperfusion injury in rats. Reviewed

    Akira Mukai, Koichi Suehiro, Aya Kimura, Yohei Fujimoto, Tomoharu Funao, Takashi Mori, Kiyonobu Nishikawa

    The Journal of thoracic and cardiovascular surgery   2020.04

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    Publishing type：Research paper (scientific journal)  

    OBJECTIVES: We aimed to investigate the protective effect of remote ischemic preconditioning against spinal cord ischemia and find a clue to its mechanism by measuring glutamate concentrations in the spinal ventral horn. METHODS: Male Sprague-Dawley rats were divided into 5 groups (n = 6 in each group) as follows: sham; SCI (only spinal cord ischemia); RIPC/SCI (perform remote ischemic preconditioning before spinal cord ischemia); MK-801/RIPC/SCI (administer MK-801, N-methyl-D-aspartate receptor antagonist, before remote ischemic preconditioning); and MK-801/SCI (administer MK-801 without remote ischemic preconditioning). Remote ischemic preconditioning was achieved by brief limb ischemia 80 minutes before spinal cord ischemia. MK-801 (1 mg/kg, intravenous) was administered 60 minutes before remote ischemic preconditioning. The glutamate concentration in the ventral horn was measured by microdialysis for 130 minutes after spinal cord ischemia. Immunofluorescence was also performed to evaluate the expression of N-methyl-D-aspartate receptor 2B subunit in the ventral horn 130 minutes after spinal cord ischemia. RESULTS: The glutamate concentrations in the spinal cord ischemia group were significantly higher than in the sham group at all time points (P < .01). Remote ischemic preconditioning attenuated the spinal cord ischemia-induced glutamate increase. When MK-801 was preadministered before remote ischemic preconditioning, glutamate concentration was increased after spinal cord ischemia (P < .01). Immunofluorescence showed that remote ischemic preconditioning prevented the increase in the expression of N-methyl-D-aspartate receptor 2B subunit on the surface of motor neurons (P = .047). CONCLUSIONS: Our results showed that remote ischemic preconditioning prevented spinal cord ischemia-induced extracellular glutamate increase in ventral horn and suppressed N-methyl-D-aspartate receptor 2B subunit expression.

    DOI： 10.1016/j.jtcvs.2020.03.094

    PubMed

  • Update on the assessment of fluid responsiveness Reviewed

    Suehiro Koichi

    JOURNAL OF ANESTHESIA   34 ( 2 )   163 - 166   2020.04（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)   Kind of work：Single Work  

    DOI： 10.1007/s00540-019-02731-4

    PubMed

  • Impact of deep breathing on predictability of stroke volume variation in spontaneous breathing patients Reviewed

    Mukai Akira, Suehiro Koichi, Kimura Aya, Kodama Sae, Tanaka Katsuaki, Mori Takashi, Nishikawa Kiyonobu

    ACTA ANAESTHESIOLOGICA SCANDINAVICA   2020.01（ ISSN:0001-5172 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/aas.13541

  • Comparison of the venous-arterial CO2 to arterial-venous O2 content difference ratio with the venous-arterial CO2 gradient for the predictability of adverse outcomes after cardiac surgery. Reviewed

    Mukai A, Suehiro K, Kimura A, Funai Y, Matsuura T, Tanaka K, Yamada T, Mori T, Nishikawa K

    Journal of clinical monitoring and computing   2019.02（ ISSN:1387-1307 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10877-019-00286-z

    PubMed

  • Reply Reviewed

    Juri Takashi, Suehiro Koichi, Nishikawa Kiyonobu

    JOURNAL OF ANESTHESIA   33 ( 1 )   166 - 166   2019.02（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-018-2589-2

  • The Sum of Early Diastolic Annulus Velocities in the Mitral and Tricuspid Valve Can Predict Adverse Events After Cardiac Surgery. Reviewed

    Mukai A, Suehiro K, Fujimoto Y, Matsuura T, Tanaka K, Funao T, Yamada T, Mori T, Nishikawa K

    Journal of cardiothoracic and vascular anesthesia   33 ( 1 )   149 - 156   2019.01（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2018.05.043

    PubMed

  • Impact of continuous non-invasive blood pressure monitoring on hemodynamic fluctuation during general anesthesia: a randomized controlled study. Reviewed

    Juri T, Suehiro K, Kimura A, Mukai A, Tanaka K, Yamada T, Mori T, Nishikawa K

    Journal of clinical monitoring and computing   32 ( 6 )   1005 - 1013   2018.12（ ISSN:1387-1307 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10877-018-0125-4

    PubMed

  • Impact of non-invasive continuous blood pressure monitoring on maternal hypotension during cesarean delivery: a randomized-controlled study. Reviewed

    Juri T, Suehiro K, Kimura A, Mukai A, Tanaka K, Yamada T, Mori T, Nishikawa K

    Journal of anesthesia   32 ( 6 )   822 - 830   2018.12（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-018-2560-2

    PubMed

  • Reduction of oxidative stress a key for enhanced postoperative recovery with fewer complications in esophageal surgery patients Randomized control trial to investigate therapeutic impact of anesthesia management and usefulness of simple blood test for prediction of high-risk patients Reviewed

    Tsuchiya Masahiko, Shiomoto Kazumasa, Mizutani Koh, Fujioka Kazuya, Suehiro Koichi, Yamada Tokuhiro, Sato Eisuke F., Nishikawa Kiyonobu

    MEDICINE   97 ( 47 )   2018.11（ ISSN:0025-7974 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1097/MD.0000000000012845

  • Pre-anesthetic stroke volume variation can predict cardiac output decrease and hypotension during induction of general anesthesia. Reviewed

    Juri T, Suehiro K, Tsujimoto S, Kuwata S, Mukai A, Tanaka K, Yamada T, Mori T, Nishikawa K

    Journal of clinical monitoring and computing   32 ( 3 )   415 - 422   2018.06（ ISSN:1387-1307 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10877-017-0038-7

    PubMed

  • Pleth variability index can predict spinal anaesthesia-induced hypotension in patients undergoing caesarean delivery Reviewed

    Kuwata S., Suehiro K., Juri T., Tsujimoto S., Mukai A., Tanaka K., Yamada T., Mori T., Nishikawa K.

    ACTA ANAESTHESIOLOGICA SCANDINAVICA   62 ( 1 )   75 - 84   2018.01（ ISSN:0001-5172 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/aas.13012

  • Fluid Management Using Minimally-invasive Hemodynamic Monitoring Reviewed

    SUEHIRO Koichi

    THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA, THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA   38 ( 4 )   496 - 503   2018（ ISSN:0285-4945 ）

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    Publishing type：Research paper (scientific journal)   Kind of work：Single Work  

    <p>Postoperative complications are the main cause of perioperative mortality and morbidity. High-risk surgical patients account for only 12.5% of all surgical procedures, but for more than 80% of postoperative mortality. Perioperative hemodynamic optimization using goal-directed therapy（GDT）has become common due to its ability to improve both of postoperative short and long-term outcomes in patients undergoing higher risk surgery. The concept of GDT in this context can be loosely defined as collecting data from minimally invasive hemodynamic monitors with the intention of using such data（flow-related parameters and/or dynamic parameters of fluid responsiveness）to titrate therapeutic interventions（intravenous fluids and/or inotropic therapy administration）with the ultimate aim of optimizing end organ tissue perfusion. Thus, GDT has grown to be considered as the standard of perioperative care, because it has demonstrated strong clinical evidence to decrease the complication rate. Despite these evidence-based recommendations, the implementation of GDT is still poorly achieved in daily clinical practice. This current review will provide a brief up-to-date overview of GDT, discuss current clinical practice, analyze why implementation has been limited, and describe the newer closed-loop GDT concept along with its potential risks and benefits.</p>

    DOI： 10.2199/jjsca.38.496

    CiNii Article

  • クリアサイトシステム Invited Reviewed

    末廣　浩一

    循環制御   39 ( 3 )   214 - 222   2018

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    Publishing type：Research paper (scientific journal)   Kind of work：Single Work  

  • Hydroxyethyl starch 130/0.4 versus crystalloid co-loading during general anesthesia induction: a randomized controlled trial Reviewed

    Juri Takashi, Suehiro Koichi, Kuwata Shigemune, Tsujimoto Sayaka, Mukai Akira, Tanaka Katsuaki, Yamada Tokuhiro, Mori Takashi, Nishikawa Kiyonobu

    JOURNAL OF ANESTHESIA   31 ( 6 )   878 - 884   2017.12（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-017-2416-1

  • Transcutaneous near-infrared spectroscopy for monitoring spinal cord ischemia: an experimental study in swine Reviewed

    Suehiro Koichi, Funao Tomoharu, Fujimoto Yohei, Mukai Akira, Nakamura Mitsuyo, Nishikawa Kiyonobu

    JOURNAL OF CLINICAL MONITORING AND COMPUTING   31 ( 5 )   975 - 979   2017.10（ ISSN:1387-1307 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10877-016-9931-8

  • Accuracy and precision of non-invasive cardiac output monitoring devices in perioperative medicine: a systematic review and meta-analysis Reviewed

    Joosten A., Desebbe O., Suehiro K., Murphy L. S. -L., Essiet M., Alexander B., Fischer M. -O., Barvais L., Van Obbergh L., Maucort-Boulch D., Cannesson M.

    BRITISH JOURNAL OF ANAESTHESIA   118 ( 3 )   298 - 310   2017.03（ ISSN:0007-0912 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1093/bja/aew461

  • Impact of advanced monitoring variables on intraoperative clinical decision-making: an international survey Reviewed

    Joosten Alexandre, Desebbe Olivier, Suehiro Koichi, Essiet Mfonobong, Alexander Brenton, Ricks Cameron, Rinehart Joseph, Faraoni David, Cecconi Maurizio, Van der Linden Philippe, Cannesson Maxime

    JOURNAL OF CLINICAL MONITORING AND COMPUTING   31 ( 1 )   205 - 212   2017.02（ ISSN:1387-1307 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10877-015-9817-1

  • Current Practice in Goal-Directed Therapy Protocol among Japanese Anesthesiologists：A Survey about Hemodynamic Monitoring and Management in High-risk Surgery Reviewed

    SUEHIRO Koichi, TANAKA Katsuaki, NISHIKAWA Kiyonobu

    THE JAPAN SOCIETY FOR CLINICAL ANESTHESIA, THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA   37 ( 2 )   211 - 218   2017（ ISSN:0285-4945 ）

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    Publishing type：Research paper (scientific journal)  

    <p>Postoperative complications are the main cause of perioperative mortality and morbidity. In addition, high-risk surgical patients account for only 12.5％ of all surgical procedures but more than 80％ of postoperative mortality. Perioperative goal-directed therapy（GDT）is one approach for improving postoperative outcomes in high-risk surgical patients. In a recent meta-analysis, it was shown that perioperative hemodynamic optimization is associated with fewer postoperative complications. Thus, GDT has come to be considered to be the standard of perioperative care because it has demonstrated strong clinical evidence to decrease the complication rate. Despite these evidence based recommendations, the implementation of GDT is still poorly achieved in daily clinical practice. Significant variability in routine GDT application could be related to different approaches and standards of specific hemodynamic monitoring. Recently, surveys on hemodynamic monitoring and management in high-risk surgery have been performed among Japanese, North American, European, Korean and Chinese anesthesiologists, which showed a considerable gap in clinical practice for hemodynamic monitoring and management among different populations. In this section, we will discuss the current application and problems of GDT protocol in Japan using data from these surveys.</p>

    DOI： 10.2199/jjsca.37.211

    CiNii Article

  • Accuracy and precision of minimally-invasive cardiac output monitoring in children: a systematic review and meta-analysis Reviewed

    Suehiro Koichi, Joosten Alexandre, Murphy Linda Suk-Ling, Desebbe Olivier, Alexander Brenton, Kim Sang-Hyun, Cannesson Maxime

    JOURNAL OF CLINICAL MONITORING AND COMPUTING   30 ( 5 )   603 - 620   2016.10（ ISSN:1387-1307 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10877-015-9757-9

  • A Novel Mobile Phone Application for Pulse Pressure Variation Monitoring Based on Feature Extraction Technology: A Method Comparison Study in a Simulated Environment Reviewed

    Desebbe Olivier, Joosten Alexandre, Suehiro Koichi, Lahham Sari, Essiet Mfonobong, Rinehart Joseph, Cannesson Maxime

    ANESTHESIA AND ANALGESIA   123 ( 1 )   105 - 113   2016.07（ ISSN:0003-2999 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1213/ANE.0000000000001282

  • Hemodynamic monitoring and management in high-risk surgery: a survey among Japanese anesthesiologists Reviewed

    Suehiro Koichi, Tanaka Katsuaki, Mukai Akira, Joosten Alexandre, Desebbe Olivier, Alexander Brenton, Cannesson Maxime, Nishikawa Kiyonobu

    JOURNAL OF ANESTHESIA   30 ( 3 )   526 - 529   2016.06（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-016-2155-8

  • Next Generation of Method-Comparison Studies: Standardization of Data Presentation and Clinical Application Are a Goal to Reach Reviewed

    Desebbe Olivier, Joosten Alexandre, Suehiro Koichi

    CRITICAL CARE MEDICINE   43 ( 10 )   E468 - E469   2015.10（ ISSN:0090-3493 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1097/CCM.0000000000001130

  • Goal-Directed fluid therapy with closed-loop assistance during moderate risk surgery using noninvasive cardiac output monitoring: A pilot study Reviewed

    Joosten A., Huynh T., Suehiro K., Canales C., Cannesson M., Rinehart J.

    BRITISH JOURNAL OF ANAESTHESIA   114 ( 6 )   886 - 892   2015.06（ ISSN:0007-0912 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1093/bja/aev002

  • Continuous noninvasive hemoglobin monitoring: ready for prime time? Reviewed

    Suehiro K, Joosten A, Alexander B, Cannesson M

    Current opinion in critical care   21 ( 3 )   265 - 270   2015.06（ ISSN:1070-5295 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1097/MCC.0000000000000197

    PubMed

  • The ability of the Vigileo-FloTrac system to measure cardiac output and track cardiac output changes during one-lung ventilation Reviewed

    Suehiro Koichi, Tanaka Katsuaki, Yamada Tokuhiro, Matsuura Tadashi, Mori Takashi, Funao Tomoharu, Nishikawa Kiyonobu

    JOURNAL OF CLINICAL MONITORING AND COMPUTING   29 ( 3 )   333 - 339   2015.06（ ISSN:1387-1307 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s10877-014-9609-z

  • Improved Performance of the Fourth-Generation FloTrac/Vigileo System for Tracking Cardiac Output Changes Reviewed

    Suehiro Koichi, Tanaka Katsuaki, Mikawa Mika, Uchihara Yuriko, Matsuyama Taiki, Matsuura Tadashi, Funao Tomoharu, Yamada Tokuhiro, Mori Takashi, Nishikawa Kiyonobu

    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA   29 ( 3 )   656 - 662   2015.06（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2014.07.022

  • The utility of intra-operative three-dimensional transoesophageal echocardiography for dynamic measurement of stroke volume Reviewed

    Suehiro K., Tanaka K., Yamada T., Matsuura T., Funao T., Mori T., Nishikawa K.

    ANAESTHESIA   70 ( 2 )   150 - 159   2015.02（ ISSN:0003-2409 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/anae.12857

  • Brain Serotonin Content Regulates the Manifestation of Tramadol-induced Seizures in Rats Disparity between Tramadol-induced Seizure and Serotonin Syndrome Reviewed

    Fujimoto Yohei, Funao Tomoharu, Suehiro Koichi, Takahashi Ryota, Mori Takashi, Nishikawa Kiyonobu

    ANESTHESIOLOGY   122 ( 1 )   178 - 189   2015.01（ ISSN:0003-3022 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1097/ALN.0000000000000434

  • 全身血管抵抗は心拍出量の測定およびその変化をモニタリングするVigileo-Flo systemの有用性に影響を及ぼす Reviewed

    末廣 浩一, 田中 克明, 舟尾 友晴, 松浦 正, 森 隆, 西川 精宣

    克誠堂出版(株)　麻酔   63 ( 増刊 )   S143 - S152   2014.11（ ISSN:0021-4892 ）

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    Publishing type：Research paper (scientific journal)  

    ビジレオフロートラックシステム(VFS)と肺動脈カテーテル法(PAC)による心拍出量を比較し、末梢血管抵抗との関係を検討した。PACを使用する心臓血管外科症例40例155組を対象とした。低SVRI 44例、正常63例、高SVRI 48例であった。フェニレフリン投与後、APCOは有意に増加したが、ICOは低SVRI、正常SVRIでは有意に変化はみられず、高SVRIで有意に減少した。フェニレフリン投与前・後のPEは、低SVRI 46.3%、41.5%、正常SVRI 26.4%、37.6%、高SVRI 61.4%、75.7%であった。CRは、低SVRI 67.5%、正常SVRI 28.8%、高SVRI 7.7%であった。angular CRが、低SVRI 42.1%、正常SVRI 25.0%、高SVRI 5.3%であった。

  • The Vigileo-FloTrac (TM) System: Arterial Waveform Analysis for Measuring Cardiac Output and Predicting Fluid Responsiveness: A Clinical Review Reviewed

    Suehiro Koichi, Tanaka Katsuaki, Matsuura Tadashi, Funao Tomoharu, Yamada Tokuhiro, Mori Takashi, Nishikawa Kiyonobu

    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA   28 ( 5 )   1361 - 1374   2014.10（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2014.02.020

  • The Impact of Intraoperative Hypothermia on Early Postoperative Adverse Events After Radical Esophagectomy for Cancer: A Retrospective Cohort Study Reviewed

    Yamasaki Hiroyuki, Tanaka Katsuaki, Funai Yusuke, Suehiro Koichi, Ikenaga Kazutake, Mori Takashi, Osugi Harushi, Nishikawa Kiyonobu

    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA   28 ( 4 )   943 - 947   2014.08（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2014.02.013

  • Preoperative hydroperoxide concentrations are associated with an increased risk of postoperative complications after cardiac surgery Reviewed

    Suehiro K., Tanaka K., Matsuura T., Funao T., Yamada T., Mori T., Tsuchiya M., Nishikawa K.

    ANAESTHESIA AND INTENSIVE CARE   42 ( 4 )   487 - 494   2014.07（ ISSN:0310-057X ）

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    Publishing type：Research paper (scientific journal)  

  • Preoperative hydroperoxide concentrations are associated with a risk of postoperative complications after cardiac surgery. Reviewed

    Suehiro K, Tanaka K, Matsuura T, Funao T, Yamada T, Mori T, Tsuchiya M, Nishikawa K

    Anaesthesia and intensive care   42 ( 4 )   487 - 494   2014.07（ ISSN:0310-057X ）

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    Publishing type：Research paper (scientific journal)  

    PubMed

  • Discrepancy Between Superior Vena Cava Oxygen Saturation and Mixed Venous Oxygen Saturation Can Predict Postoperative Complications in Cardiac Surgery Patients Reviewed

    Suehiro Koichi, Tanaka Katsuaki, Matsuura Tadashi, Funao Tomoharu, Yamada Tokuhiro, Mori Takashi, Nishikawa Kiyonobu

    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA   28 ( 3 )   528 - 533   2014.06（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2013.03.002

  • Detection of Left Ventricular Dysfunction Using Early Diastolic Mitral Annular Velocity in Patients Undergoing Mitral Valve Repair for Mitral Regurgitation Reviewed

    Suehiro Koichi, Tanaka Katsuaki, Matsuura Tadashi, Funao Tomoharu, Yamada Tokuhiro, Mori Takashi, Nishikawa Kiyonobu

    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA   28 ( 1 )   25 - 30   2014.02（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2013.07.013

  • Systemic vascular resistance has an impact on the reliability of the Vigileo-FloTrac system in measuring cardiac output and tracking cardiac output changes Reviewed

    Suehiro K., Tanaka K., Funao T., Matsuura T., Mori T., Nishikawa K.

    BRITISH JOURNAL OF ANAESTHESIA   111 ( 2 )   170 - 177   2013.08（ ISSN:0007-0912 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1093/bja/aet022

  • Relationship between noradrenaline release in the locus coeruleus and antiallodynic efficacy of analgesics in rats with painful diabetic neuropathy Reviewed

    Suehiro Koichi, Funao Tomoharu, Fujimoto Yohei, Yamada Tokuhiro, Mori Takashi, Nishikawa Kiyonobu

    LIFE SCIENCES   92 ( 23 )   1138 - 1144   2013.06（ ISSN:0024-3205 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.lfs.2013.04.015

  • Transversus abdominis plane block in combination with general anesthesia provides better intraoperative hemodynamic control and quicker recovery than general anesthesia alone in high-risk abdominal surgery patients Reviewed

    Tsuchiya M., Takahashi R., Furukawa A., Suehiro K., Mizutani K., Nishikawa K.

    MINERVA ANESTESIOLOGICA   78 ( 11 )   1241 - 1247   2012.11（ ISSN:0375-9393 ）

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    Publishing type：Research paper (scientific journal)  

  • Stroke volume variation as a predictor of fluid responsiveness in patients undergoing airway pressure release ventilation Reviewed

    Suehiro K., Rinka H., Ishikawa J., Fuke A., Arimoto H., Miyaichi T.

    ANAESTHESIA AND INTENSIVE CARE   40 ( 5 )   767 - 772   2012.09（ ISSN:0310-057X ）

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    Publishing type：Research paper (scientific journal)  

  • Landiolol attenuates cardiovascular response at induction of general anesthesia for cesarean delivery. Reviewed

    Suehiro K, Okutani R

    Journal of anesthesia   26 ( 2 )   200 - 205   2012.04（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-011-1305-2

    PubMed

  • Influence of tidal volume for stroke volume variation to predict fluid responsiveness in patients undergoing one-lung ventilation. Reviewed

    Suehiro K, Okutani R

    Journal of anesthesia   25 ( 5 )   777 - 780   2011.10（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-011-1200-x

    PubMed

  • Duration of cerebral desaturation time during single-lung ventilation correlates with mini mental state examination score. Reviewed

    Suehiro K, Okutai R

    Journal of anesthesia   25 ( 3 )   345 - 349   2011.06（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-011-1136-1

    PubMed

  • Perioperative complications in patients with end-stage renal disease undergoing pulmonary resection Reviewed

    Koichi Suehiro, Ryu Okutani

    Journal of Anesthesia and Clinical Research   2 ( 3 )   1 - 4   2011.03（ ISSN:2155-6148 ）

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    Publishing type：Research paper (scientific journal)  

    Introduction: Among the perioperative complications encountered in patients with renal failure, there is a high risk of events such as heart failure and increased susceptibility to infection. Herein, we report the results of our investigation of perioperative management in patients with chronic renal failure who underwent a pulmonary resection. Methods: The subjects were 21 hemodialysis patients with renal failure who underwent pulmonary resection for lung cancer. We retrospectively investigated their clinical characteristics and perioperative management. The patients were classified into two groups
    those with and without symptoms of postoperative acute heart failure. Intergroup comparisons of preoperative examinations and management were performed. Results: The most common preoperative comorbidity was cardiac complications, which occurred at a high incidence of 38%. There were no serious perioperative complications. In contrast, postoperative complications associated with renal failure were numerous, including acute heart failure in 3 (14%) and hyperkalemia in 2 (9.5%). We concluded that preoperative respiratory function, intraoperative fluid infusion volume, and preoperative cardiac comorbidities are potential risk factors for postoperative heart failure in such patients. Conclusion: Although there were no cases with perioperative mortality, postoperative complications were encountered, including heart failure and hyperkalemia, suggesting that more stringent cardiovascular and respiratory management techniques are necessary. © 2011 Suehiro K, et al.

    DOI： 10.4172/2155-6148.1000127

  • Cerebral desaturation during single-lung ventilation is negatively correlated with preoperative respiratory functions. Reviewed

    Suehiro K, Okutai R

    Journal of cardiothoracic and vascular anesthesia   25 ( 1 )   127 - 130   2011.02（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2010.02.013

    PubMed

  • Stroke volume variation as a predictor of fluid responsiveness in patients undergoing one-lung ventilation. Reviewed

    Suehiro K, Okutani R

    Journal of cardiothoracic and vascular anesthesia   24 ( 5 )   772 - 775   2010.10（ ISSN:1053-0770 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1053/j.jvca.2010.03.014

    PubMed

  • Anesthetic considerations in 65 patients undergoing unilateral pneumonectomy: problems related to fluid therapy and hemodynamic control. Reviewed

    Suehiro K, Okutani R, Ogawa S

    Journal of clinical anesthesia   22 ( 1 )   41 - 44   2010.02（ ISSN:0952-8180 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jclinane.2009.02.013

    PubMed

  • Spike-monitoring of anaesthesia for corpus callosotomy using bilateral bispectral index. Reviewed

    Ogawa S, Okutani R, Nakada K, Suehiro K, Shigemoto T

    Anaesthesia   64 ( 7 )   776 - 780   2009.07（ ISSN:0003-2409 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1111/j.1365-2044.2009.05917.x

    PubMed

  • Anesthetic management using total intravenous anesthesia with remifentanil in a child with osteogenesis imperfecta. Reviewed

    Ogawa S, Okutani R, Suehiro K

    Journal of anesthesia   23 ( 1 )   123 - 125   2009（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-008-0698-z

    PubMed

  • Perioperative management of a neonate with Cantrell syndrome. Reviewed

    Suehiro K, Okutani R, Ogawa S, Nakada K, Shimaoka H, Ueda M, Shigemoto T

    Journal of anesthesia   23 ( 4 )   572 - 575   2009（ ISSN:0913-8668 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s00540-009-0785-9

    PubMed

▼display all

Books and Other Publications

  • 低侵襲血行動態モニタリング

    末廣浩一（ Role： Sole author）

    心臓血管麻酔 Positive and Negative リスト25  2020 

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    Responsible for pages：88-95  

MISC

  • 【最新主要文献とガイドラインでみる　麻酔科学レビュー　2021】内視鏡手術の麻酔

    末廣 浩一

    麻酔科学レビュー   2021   197 - 201   2021.05（ ISSN:1884-8516 ）

  • 低侵襲血行動態モニタを用いた循環管理に関する最近の知見 Reviewed

    末廣 浩一

    真興交易(株)医書出版部　臨床麻酔   45 ( 1 )   51 - 57   2021.01（ ISSN:0387-3668 ）

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    Publishing type：Article, review, commentary, editorial, etc. (scientific journal)   Kind of work：Single Work  

  • 機器紹介　クリアサイトシステム Reviewed

    末廣 浩一

    日本循環制御医学会　循環制御   39 ( 3 )   214 - 222   2019.01（ ISSN:0389-1844 ）

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    Publishing type：Article, review, commentary, editorial, etc. (scientific journal)   Kind of work：Single Work  

  • これからの術中輸液・輸血管理　低侵襲血行動態モニターを用いた輸液管理 Reviewed

    末廣 浩一

    日本臨床麻酔学会　日本臨床麻酔学会誌   38 ( 4 )   496 - 503   2018.07（ ISSN:0285-4945 ）

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    Publishing type：Article, review, commentary, editorial, etc. (scientific journal)   Kind of work：Single Work  

    中等度リスクの症例は手術数全体の40%程度を占めると推定されている。これらの症例ではハイリスクなものと比較して重症合併症は少ないものの、約30%に何らかの術後合併症が生じていることが報告されている。Goal-directed therapy(GDT)は術後合併症を軽減し、予後を改善する可能性が示唆されているが、GDTの適用率は本邦においても低いのが現状である。本邦におけるGDTの低施行率の理由としては、GDTのエビデンスレベル、GDTプロトコールの複雑さや多様性などの問題点が挙げられる。本稿ではGDTプロトコールを中心に低侵襲血行動態モニターを使用した輸液管理について考察し、GDTプロトコールの問題点を解決する可能性がある自動輸液負荷システムについて概説を行う。(著者抄録)

  • Goal-Directed Therapy(目標指向型輸液療法)の実践　国内外の実例を交えて　本邦におけるGDTの実施状況等について Reviewed

    末廣 浩一, 田中 克明, 西川 精宣

    日本臨床麻酔学会　日本臨床麻酔学会誌   37 ( 2 )   211 - 218   2017.03（ ISSN:0285-4945 ）

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    Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

    ハイリスク手術症例は手術数全体の12.5%程度しか占めていないにもかかわらず,術後死亡数の80%以上を占めるとされる.Goal-directed therapy(GDT)はハイリスク症例において予後を改善する可能性が示唆されているが,GDTの適用に関して特に基準はなく,また施設によって使用するモニターやプロトコールなどもさまざまである.2014年にわれわれは日本麻酔科学会認定施設を対象として,ハイリスク症例における血行動態モニタリングに関する調査を行った.本稿ではわれわれの調査結果を踏まえて,本邦におけるGDTの施行状況やGDTを行っていく上での問題点を考察したい.(著者抄録)

Presentations

  • Corrected Flow Timeの輸液負荷後血圧変化の指標としての有用性の検討

    末廣 浩一, 渡邉 亮太, 重里 尚, 堀 耕太郎, 山田 徳洪, 森 隆

    日本集中治療医学会雑誌  2022.11  (一社)日本集中治療医学会

  • 周術期循環管理の将来像 Domestic conference

    末廣浩一

    第9回周術期代謝管理検討会  2019.03 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 周術期輸液管理における膠質液の活用法 Domestic conference

    末廣浩一

    Otsuka Live on Seminar  2019.02 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 周術期循環管理の将来像 Domestic conference

    末廣浩一

    第64回広島麻酔医学会総会  2019.01 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 心臓血管麻酔における血行動態モニタリング Domestic conference

    末廣浩一

    第23回日本心臓血管麻酔学会学術集会  2018.09 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 周術期輸液管理の現在と未来 Domestic conference

    末廣浩一

    第6回京都周術期代謝管理セミナー  2018.06 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 区域麻酔における血行動態管理 Domestic conference

    末廣浩一

    日本区域麻酔学会第5回学術集会  2018.04 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 周術期輸液管理の現在と未来 Domestic conference

    末廣浩一

    第8回麻酔周術期医学講演会  2017.11 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 周術期輸液管理の現在と未来 Domestic conference

    末廣浩一

    平成29年度富山麻酔科医会研究会  2017.11 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 心臓手術における血行動態モニタリング Domestic conference

    末廣浩一

    第22回日本心臓血管麻酔学会学術集会  2017.09 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 低侵襲血行動態モニターを用いた周術期循環管理 Domestic conference

    末廣浩一

    第1回周術期・心拍出量モニタリングセミナー  2017.09 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 周術期輸液管理の現在と未来 Domestic conference

    末廣浩一

    第64回日本麻酔科学会  2017.06 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 第3世代HES 130/0.4/9を用いた周術期血行動態管理 Domestic conference

    末廣浩一

    第1回兵庫周術期管理セミナー  2017.03 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 第3世代HES 130/0.4/9(ボルベン®）を用いた周術期血行動態管理 Domestic conference

    末廣浩一

    第36回臨床麻酔学会  2016.11 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • 周術期輸液管理の意義と本邦における現状 Domestic conference

    末廣浩一

    周術期水分管理セミナー大阪  2016.10 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • クリアサイトシステムを用いた血行動態管理 Domestic conference

    末廣浩一

    第62回日本麻酔科学会関西支部学術集会  2016.09 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • ボルベンを用いた周術期血行動態管理 Domestic conference

    末廣浩一

    Fluid Management Seminar in Osaka  2015.10 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • Vigileo-FloTrac systemを用いたGoal-Directed Therapy Domestic conference

    末廣浩一

    第22回経食道心エコー講習会  2015.07 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • Systemic vascular resistance has an impact on the reliability of the Vigileo-FloTrac system in measuring cardiac output and tracking cardiac output changes Domestic conference

    末廣浩一

    第61回日本麻酔科学会  2014.05 

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    Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  • APRVで呼吸管理を行っているARDS症例においてSVVは輸液反応性の指標として有効である

    末廣 浩一, 林下 浩士, 森本 健, 細見 早苗, 石川 順一, 福家 顕宏, 有元 秀樹, 宮市 功典, 韓 正訓, 鍜冶 有登

    日本集中治療医学会雑誌  2011.01  (一社)日本集中治療医学会

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Grant-in-Aid for Scientific Research

  • 超低体温循環停止における水素吸入の腎保護効果 -グリコカリックス障害の観点から-

    Grant-in-Aid for Scientific Research(C)  2026

  • 超低体温循環停止における水素吸入の腎保護効果 -グリコカリックス障害の観点から-

    Grant-in-Aid for Scientific Research(C)  2025

  • 超低体温循環停止における水素吸入の腎保護効果 -グリコカリックス障害の観点から-

    Grant-in-Aid for Scientific Research(C)  2024

  • 虚血性脊髄障害に対する水素吸入の治療効果－脊髄マイクロダイアライシスによる検討－

    Grant-in-Aid for Young Scientists(B)  2018.04

  • 脊髄虚血における脊髄前角グルタミン酸濃度の測定ー脊髄虚血機序の解明

    Grant-in-Aid for Young Scientists(B)  2015.04

Outline of education staff

  • Hemodynamic management in the perioperative period

Charge of on-campus class subject

  • 麻酔科学

    2020     Undergraduate

  • 麻酔科学

    2019     Undergraduate

  • 麻酔科学

    2018     Undergraduate

  • 麻酔科学

    2017     Undergraduate

  • 麻酔科学

    2016     Undergraduate

  • 麻酔科学

    2015     Undergraduate

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Other

  • Job Career

    2015.04 - Now

  • Job Career

    2011.04 - 2014.03