2024/03/22 更新

写真a

ミヤワキ ヒロユキ
宮脇 寛行
MIYAWAKI Hiroyuki
担当
大学院医学研究科 基礎医科学専攻 講師
医学部 医学科
職名
講師
所属
医学研究院

担当・職階

  • 大学院医学研究科 基礎医科学専攻 

    講師  2022年07月 - 継続中

  • 大学院医学研究科 基礎医科学専攻 

    助教  2022年04月 - 2022年06月

  • 医学部 医学科 

    講師  2022年07月 - 継続中

  • 医学部 医学科 

    助教  2022年04月 - 2022年06月

取得学位

  • 博士(理学) ( 京都大学 )

  • 修士 ( 京都大学 )

研究分野

  • ライフサイエンス / 神経科学一般

研究キーワード

  • 電気生理学

  • 記憶

研究概要

  • 記憶の形成、固定、想起のメカニズム

所属学協会

  • 北米神経科学学会

      国外

  • 日本神経科学学会

      国内

  • 日本生理学会

委員歴(学外)

  • 近畿生理学談話会 プログラム委員   日本生理学会  

    2016年11月 

受賞歴

  • 学長表彰

    2023年03月   大阪公立大学  

  • 医学部長賞 奨励賞

    2023年03月   大阪公立大学  

  • 大阪市立大学 教員活動表彰(若手教員の教育研究活動分野)

    2019年06月  

  • 教員活動表彰(若手教員の教育研究活動分野)

    宮脇 寛行

    2019年06月   大阪市立大学  

職務経歴(学外)

  • ウィスコンシン大学ミルウォーキー校   心理学部   博士研究員

    2011年04月 - 2016年07月

学歴

  • 京都大学   大学院理学研究科   生物物理学教室 博士課程   博士課程   卒業・修了

    2007年04月 - 2011年03月

  • 京都大学   大学院理学研究科   生物物理学教室 修士課程   修士課程   卒業・修了

    2005年04月 - 2007年03月

  • 京都大学   理学部     卒業・修了

    2000年04月 - 2005年03月

論文

  • Acquisition of Auditory Discrimination Mediated by Different Processes through Two Distinct Circuits Linked to the Lateral Striatum 査読

    Susumu Setogawa, Takashi Okauchi, Di Hu, Yasuhiro Wada, Keigo Hikishima, Hirotaka Onoe, Kayo Nishizawa, Nobuyuki Sakayori, Hiroyuki Miyawaki, Takuma Kitanishi, Kenji Mizuseki, Yilong Cui, Kazuto Kobayashi

    2023年10月

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    掲載種別:研究論文(学術雑誌)  

    The striatum, the central hub of cortico-basal ganglia loops, contains functionally heterogeneous subregions distinguished by the topographic patterns of structural connectivity. These subregions mediate various processes of procedural learning. However, it remains unclear when and how striatal subregions engage in a new learning of sensory stimulus-based decision-making. Here, we show that the anterior dorsolateral striatum (aDLS) and posterior ventrolateral striatum (pVLS) are activated in a different temporal pattern during the acquisition phase of auditory discrimination learning. The aDLS promotes the behavioral strategy by the stimulus-response association while suppressing those driven by the response-outcome association, and the pVLS is involved in forming and maintaining the stimulus-response strategy. These two subregions exhibit distinct event-related neuronal responses during the learning processes. Our findings demonstrate that aDLS and pVLS neurons integrate the new learning of auditory discrimination in spatiotemporally and functionally different manners.

    DOI: 10.1101/2023.10.19.563198

  • Fast network oscillations during non-REM sleep support memory consolidation. 査読

    Mizuseki K, Miyawaki H

    Neuroscience research   189   3 - 12   2023年04月( ISSN:0168-0102

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.neures.2022.12.019

    PubMed

  • De novo inter-regional coactivations of preconfigured local ensembles support memory. 査読

    Miyawaki H, Mizuseki K

    Nature communications   13 ( 1 )   1272 - 1272   2022年03月

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)   国際・国内誌:国際誌  

    DOI: 10.1038/s41467-022-28929-x

    PubMed

  • Author Correction: Neuronal firing rates diverge during REM and homogenize during non-REM. 査読

    Miyawaki H, Watson BO, Diba K

    Scientific reports   11 ( 1 )   23772   2021年12月

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.1038/s41598-021-02856-1

    PubMed

  • 3D-printed Recoverable Microdrive and Base Plate System for Rodent Electrophysiology. 査読

    Vöröslakos M, Miyawaki H, Royer S, Diba K, Yoon E, Petersen PC, Buzsáki G

    Bio-protocol   11 ( 16 )   e4137   2021年08月( ISSN:2331-8325

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.21769/BioProtoc.4137

    PubMed

  • 恐怖記憶の基盤となる全脳ダイナミクスの解明 査読

    宮脇 寛行

    (公財)上原記念生命科学財団 上原記念生命科学財団研究報告集   33   1 - 4   2019年12月

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    掲載種別:研究論文(学術雑誌)   共著区分:単著  

  • Hippocampal Reactivation Extends for Several Hours Following Novel Experience 査読 国際共著

    Giri Bapun, Miyawaki Hiroyuki, Mizuseki Kenji, Cheng Sen, Diba Kamran

    JOURNAL OF NEUROSCIENCE   39 ( 5 )   866 - 875   2019年01月( ISSN:0270-6474

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    New memories are believed to be consolidated over several hours of post-task sleep. The reactivation or “replay” of hippocampal cell assemblies has been proposed to provide a key mechanism for this process. However, previous studies have indicated that such replay is restricted to the first 10–30 min of post-task sleep, suggesting that it has a limited role in memory consolidation. We performed long-duration recordings in sleeping and behaving male rats and applied methods for evaluating the reactivation of neurons in pairs as well as in larger ensembles while controlling for the continued activation of ensembles already present during pre-task sleep (“preplay”). We found that cell assemblies reactivate for up to 10 h, with a half-maximum timescale of ∼6 h, in sleep following novel experience, even when corrected for preplay. We further confirmed similarly prolonged reactivation in post-task sleep of rats in other datasets that used behavior in novel environments. In contrast, we saw limited reactivation in sleep following behavior in familiar environments. Overall, our findings reconcile the duration of replay with the timescale attributed to cellular memory consolidation and provide strong support for an integral role of replay in memory.

    DOI: 10.1523/JNEUROSCI.1950-18.2018

    PubMed

  • Neuronal firing rates diverge during REM and homogenize during non-REM 査読

    Miyawaki Hiroyuki, Watson Brendon O., Diba Kamran

    SCIENTIFIC REPORTS   9 ( 1 )   689   2019年01月( ISSN:2045-2322

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Neurons fire at highly variable intrinsic rates and recent evidence suggests that low- and high-firing rate neurons display different plasticity and dynamics. Furthermore, recent publications imply possibly differing rate-dependent effects in hippocampus versus neocortex, but those analyses were carried out separately and with potentially important differences. To more effectively synthesize these questions, we analyzed the firing rate dynamics of populations of neurons in both hippocampal CA1 and frontal cortex under one framework that avoids the pitfalls of previous analyses and accounts for regression to the mean (RTM). We observed several consistent effects across these regions. While rapid eye movement (REM) sleep was marked by decreased hippocampal firing and increased neocortical firing, in both regions firing rate distributions widened during REM due to differential changes in high- versus low-firing rate cells in parallel with increased interneuron activity. In contrast, upon non-REM (NREM) sleep, firing rate distributions narrowed while interneuron firing decreased. Interestingly, hippocampal interneuron activity closely followed the patterns observed in neocortical principal cells rather than the hippocampal principal cells, suggestive of long-range interactions. Following these undulations in variance, the net effect of sleep was a decrease in firing rates. These decreases were greater in lower-firing hippocampal neurons but also higher-firing frontal cortical neurons, suggestive of greater plasticity in these cell groups. Our results across two different regions, and with statistical corrections, indicate that the hippocampus and neocortex show a mixture of differences and similarities as they cycle between sleep states with a unifying characteristic of homogenization of firing during NREM and diversification during REM.

    DOI: 10.1038/s41598-018-36710-8

    PubMed

  • Hippocampal Information Processing and Homeostatic Regulation During REM and Non-REM Sleep 査読

    Mizuseki K, Miyawaki H

    Handbook of Behavioral Neuroscience   30   49 - 62   2019年( ISBN:9780128137437

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    The synchronous activity of populations of neurons in patterns known as sharp-wave ripples (SPW-Rs), which contain fragments of time-compressed neuronal sequences that are replayed from those experienced during waking hours, is thought to mediate the transfer of newly acquired hippocampal information to distributed circuits in support of memory consolidation. Consistent with this hypothesis, it has been shown that the perturbation of neuronal activity during SPW-Rs can lead to memory impairment. Waking theta states and rapid eye movement (REM) sleep involve different kinds of temporal coordination in the hippocampal-entorhinal circuit, reflecting the distinct balance of hippocampal and entorhinal input to the CA1 area. The firing rates of individual neurons follow lognormal-like distributions in all brain states. Fast-firing minority and slow-firing majority neurons, which support system stability and mnemonic functions, are under distinct firing-rate regulation that is initiated by spindles and SPW-Rs during non-REM sleep and implemented during REM sleep.

  • Low Activity Microstates During Sleep 査読

    Miyawaki Hiroyuki, Billeh Yazan N., Diba Kamran

    SLEEP   40 ( 6 )   2017年06月( ISSN:1550-9109

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    STUDY OBJECTIVES:
    To better understand the distinct activity patterns of the brain during sleep, we observed and investigated periods of diminished oscillatory and population spiking activity lasting for seconds during non-rapid eye movement (non-REM) sleep, which we call "LOW" activity sleep.

    METHODS:
    We analyzed spiking and local field potential (LFP) activity of hippocampal CA1 region alongside neocortical electroencephalogram (EEG) and electromyogram (EMG) in 19 sessions from four male Long-Evans rats (260-360 g) during natural wake/sleep across the 24-hr cycle as well as data from other brain regions obtained from http://crcns.org.1,2.

    RESULTS:
    LOW states lasted longer than OFF/DOWN states and were distinguished by a subset of "LOW-active" cells. LOW activity sleep was preceded and followed by increased sharp-wave ripple activity. We also observed decreased slow-wave activity and sleep spindles in the hippocampal LFP and neocortical EEG upon LOW onset, with a partial rebound immediately after LOW. LOW states demonstrated activity patterns consistent with sleep but frequently transitioned into microarousals and showed EMG and LFP differences from small-amplitude irregular activity during quiet waking. Their likelihood decreased within individual non-REM epochs yet increased over the course of sleep. By analyzing data from the entorhinal cortex of rats,1 as well as the hippocampus, the medial prefrontal cortex, the postsubiculum, and the anterior thalamus of mice,2 obtained from http://crcns.org, we confirmed that LOW states corresponded to markedly diminished activity simultaneously in all of these regions.

    CONCLUSIONS:
    We propose that LOW states are an important microstate within non-REM sleep that provide respite from high-activity sleep and may serve a restorative function.

    DOI: 10.1093/sleep/zsx066

    PubMed

  • Hippocampal information processing across sleep/wake cycles 査読

    Mizuseki Kenji, Miyawaki Hiroyuki

    NEUROSCIENCE RESEARCH   118   30 - 47   2017年05月( ISSN:0168-0102

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    According to a two-stage memory consolidation model, during waking theta states, afferent activity from the neocortex to the hippocampus induces transient synaptic modification in the hippocampus, where the information is deposited as a labile form of memory trace. During subsequent sharp-wave ripples (SPW-Rs), the newly acquired hippocampal information is transferred to the neocortex and stored as a long-lasting memory trace. Consistent with this hypothesis, waking theta states and SPW-Rs distinctly control information flow in the hippocampal–entorhinal loop. Although both waking theta states and rapid eye movement (REM) sleep are characterized by prominent hippocampal theta oscillations, the two brain states involve distinct temporal coordination and oscillatory coupling in the hippocampal–entorhinal circuit. While distinct brain states have distinct network dynamics, firing rates of individual neurons in the hippocampal–entorhinal circuitry follow lognormal-like distributions in all states. Firing rates of the same neurons are positively correlated across brain states and testing environments, suggesting that memory is allocated in preconfigured, rather than tabula rasa-type, skewed neuronal networks. The fast-firing minority and slow-firing majority neurons, which can support network stability and flexibility, are under distinct homeostatic regulations that are initiated by spindles and SPW-Rs during slow wave sleep and implemented during subsequent REM sleep.

    DOI: 10.1016/j.neures.2017.04.018

    PubMed

  • Regulation of Hippocampal Firing by Network Oscillations during Sleep. 査読 国際共著

    Miyawaki H, Diba K

    Current biology : CB   26 ( 7 )   893 - 902   2016年04月( ISSN:0960-9822

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    It has been hypothesized that waking leads to higher-firing neurons, with increased energy expenditure, and that sleep serves to return activity to baseline levels. Oscillatory activity patterns during different stages of sleep may play specific roles in this process, but consensus has been missing. To evaluate these phenomena in the hippocampus, we recorded from region CA1 neurons in rats across the 24-hr cycle, and we found that their firing increased upon waking and decreased 11% per hour across sleep. Waking and sleeping also affected lower- and higher-firing neurons differently. Interestingly, the incidences of sleep spindles and sharp-wave ripples (SWRs), typically associated with cortical plasticity, were predictive of ensuing firing changes and were more robustly predictive than other oscillatory events. Spindles and SWRs were initiated during non-REM sleep, yet the changes were incorporated in the network over the following REM sleep epoch. These findings indicate an important role for spindles and SWRs and provide novel evidence of a symbiotic relationship between non-REM and REM stages of sleep in the homeostatic regulation of neuronal activity.

    DOI: 10.1016/j.cub.2016.02.024

    PubMed

    J-GLOBAL

  • Prefrontal activity links nonoverlapping events in memory. 査読 国際共著

    Gilmartin MR, Miyawaki H, Helmstetter FJ, Diba K

    The Journal of neuroscience : the official journal of the Society for Neuroscience   33 ( 26 )   10910 - 4   2013年06月( ISSN:0270-6474

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    The medial prefrontal cortex (mPFC) plays an important role in memory. By maintaining a working memory buffer, neurons in prelimbic (PL) mPFC may selectively contribute to learning associations between stimuli that are separated in time, as in trace fear conditioning (TFC). Until now, evidence for this bridging role was largely descriptive. Here we used optogenetics to silence neurons in the PL mPFC of rats during learning in TFC. Memory formation was prevented when mPFC was silenced specifically during the interval separating the cue and shock. Our results provide support for a working memory function for these cells and indicate that associating two noncontiguous stimuli requires bridging activity in PL mPFC.

    DOI: 10.1523/JNEUROSCI.0144-13.2013

    PubMed

    J-GLOBAL

  • Different correlations among physiological and morphological properties at single glutamatergic synapses in the rat hippocampus and the cerebellum. 査読

    Miyawaki H, Hirano T

    Synapse (New York, N.Y.)   65 ( 5 )   412 - 23   2011年05月( ISSN:0887-4476

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Synapses in the mammalian central nervous system show substantial diversity in their physiological and morphological properties. However, the correlations among them have remained elusive. Here, we tried to clarify the correlations by establishing a method to record excitatory postsynaptic currents (EPSCs) at individual synapses and also to observe the morphology at the same time. A pair of pre‐ and postsynaptic neurons were labeled with different fluorescent dyes, and a presynaptic varicosity was selectively stimulated with a θ‐tube glass electrode under conditions in which action potential generation was suppressed. Two representative types of excitatory glutamatergic synapses, one on hippocampal pyramidal neurons and the other on cerebellar Purkinje neurons, were studied. The correlations between the properties of quantal EPSCs (qEPSCs) and those of synaptic morphology were analyzed in rat primary culture preparations. The amplitude and the decay time of qEPSC were correlated with the size of the postsynaptic spine only at hippocampal synapses. In contrast, the size of the presynaptic varicosity was correlated with the size of the postsynaptic spine and the quantal content of evoked EPSCs only at granule neuron–Purkinje neuron synapses in the cerebellum. These results suggest that the interaction between pre‐ and postsynaptic structures and the coupling of postsynaptic responsiveness and the spine morphology differ between cerebellar and hippocampal glutamatergic synapses.

    DOI: 10.1002/syn.20860

    PubMed

    J-GLOBAL

  • Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells. 査読 国際共著

    Muguruma K, Nishiyama A, Ono Y, Miyawaki H, Mizuhara E, Hori S, Kakizuka A, Obata K, Yanagawa Y, Hirano T, Sasai Y

    Nature neuroscience   13 ( 10 )   1171 - 80   2010年10月( ISSN:1097-6256

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    プルキンエ細胞は小脳皮質における唯一の出力細胞であり、その機能障害は重篤な運動失調を引き起こす。本研究では、自己誘導された峡部オーガナイザーの微小環境からシグナルを捉えることにより、小脳プルキンエ細胞がマウスの胚性幹細胞(ES細胞)から安定的に形成されることを発見した。細胞表面のマーカー分子Neph3を用いることにより、成熟プルキンエ細胞と同様の樹状突起分枝パターンを有しプルキンエ細胞特異的マーカーであるグルタミン酸受容体δ2サブユニットを発現するプルキンエ細胞前駆体を前もって選択することが可能となった。これらの細胞は成熟プルキンエ細胞と同様の特徴的な自発発火パターンを示し、これらの細胞への興奮性シナプス入力は非NMDA型グルタミン酸受容体を介したものであった。蛍光フローサイトメトリーにより分離された前駆細胞を胎生移植すると、プルキンエ細胞層に同所性に組み込まれ、その軸索は小脳核に到達し樹状突起は登上線維および平行線維からの入力を受けることが見いだされた。この小脳プルキンエ細胞の分化誘導法はこの重要な神経細胞の研究に対するさらなる研究の礎となるものである。

    DOI: 10.1038/nn.2638

    PubMed

    J-GLOBAL

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MISC(その他記事)

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講演・口頭発表等

  • NREM-active and REM-active cells in the limbic and cortical regions are differently modulated by fast network oscillations and behaviors(タイトル和訳中) 国内会議

    Kajiya Risa, Miyawaki Hiroyuki, Mizuseki Kenji

    The Journal of Physiological Sciences  2023年05月  (一社)日本生理学会

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    会議種別:口頭発表(一般)  

  • Mechanisms of hippocampal function revealed by in vivo large-scale recording Hippocampal-cortical network dynamics elucidated with multi-regional in vivo large-scale electrophysiology(タイトル和訳中) 国内会議

    Miyawaki Hiroyuki

    The Journal of Physiological Sciences  2023年05月  (一社)日本生理学会

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    会議種別:口頭発表(一般)  

  • Hippocampal-cortical network dynamics elucidated with multi-regional in vivo large-scale electrophysiology

    Hiroyuki Miyawaki

    The 100th Anniversary Annual Meeting of The Physiological Society of Japan  2023年03月 

  • Local and Global Network Dynamics Supporting Memory 招待

    Hiroyuki Miyawaki

    2022年12月 

  • 経験依存的に発達するlocal cellensemblesの記憶を支える領域間ネットワーク(Memory-supporting inter-regional networks among local cellensembles developed in experience dependent manner) 国内会議

    Miyawaki Hiroyuki, Mizuseki Kenji

    The Journal of Physiological Sciences  2022年12月  (一社)日本生理学会

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    会議種別:口頭発表(一般)  

  • Experience-dependent inter-regional coactivations of cell ensembles support memory.

    Hiroyuki Miyawaki

    The 44th Annual Meeting of the Japan Neuroscience Society  2022年07月 

  • 恐怖記憶を支える脳領域横断的なセル・アンサンブルの同期活動の多領域同時・大規模電気生理学記録法を用いた解析(Multi-regional large-scale electrophysiology revealed that inter-regional coactivations of cell ensembles support fear memory) 国内会議

    Miyawaki Hiroyuki, Mizuseki Kenji

    The Journal of Physiological Sciences  2021年08月  (一社)日本生理学会

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    会議種別:口頭発表(一般)  

  • Homeostatic regulation of hippocampal firing during extended waking and sleep. 招待 国際会議

    Hiroyuki Miyawaki

    International Workshop on Cutting Edge Tools in Neuroscience  2015年07月  CETneuro

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    会議種別:口頭発表(招待・特別)  

    開催地:Ribeirão Preto, Brazil  

    Sleep positively impacts various types of memories, including those that are hippocampal dependent. However, it is still not clear how hippocampal activity changes during sleep. To investigate this, we performed in vivo large-scale electrophysiological recordings on hippocampal CA1 region of rats in natural awake/sleep cycles. We recorded neuronal activity continuously up to 72 hours in 12-hour light and 12-hour dark cycles. In rodents, sleep consists of two distinct states. One is REM (rapid eye movement) that is characterized by an increase in power in the theta band (5-10 Hz). The other is non-REM that is characterized by transient oscillatory events - sleep spindles and sharp wave ripples (SWRs) and continuous slow (0.5 - 4Hz) oscillation. We found that non-REM firing rates decreased during long-lasting sleep, in contrast to extended wake states where firing rates increased gradually in the hippocampus. In addition, incidences of sleep spindles and SWRs and slow-wave amplitudes decreased across sleep. These changes were not correlated with circadian cycles. These results demonstrate that hippocampal activities depend on sleep/awake history. In the triplets of non-REM1/REM/non-REM2, mean firing rates in non-REM2 were significantly lower than in non-REM1. Firing rates in non-REM1 tightly coupled with changes in firing rates between non-REM1 and non-REM2. In addition, incidence of sleep spindles and SWRs were also strongly correlated with firing rates and the firing rates changes. As previously reported by Grosmark et al. (2012), we observed significant correlation between firing rate changes between non-REM epochs and power in theta during interleaved REM. However, this correlation was weaker than incidence of spindles, SWRs, or firing rates in non-REM. In addition, we found firing rates in non-REM were predictive of theta power in the following REM. These results indicate more “excitable” states induce larger decrease of firing in the hippocampus. We also investigated correlation between hippocampal firing and slow wave oscillation. In the neocortex, it is argued that slow-wave oscillations have a role to decrease neuronal firing through downscaling synaptic connectivity (Tononi & Cirelli, 2014). However, we did not find significant correlations between slow-wave oscillations in the hippocampus and firing rates or changes in firing rates, which may indicate the hippocampus operate under a different set of rules from the neocortex. We found that hippocampal activity gradually decreased across sleep, and enhanced excitability in the hippocampus induced large decrease of hippocampal firing, which may contribute to maintain homeostasis in the hippocampus.

  • 経験依存的に生じる脳領域横断的な局所アンサンブルの同期活動 招待

    宮脇寛行

    理学研究所研究会「大脳皮質を中心とした神経回路:構造と機能、その動作原理」 

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科研費

  • 記憶の固定化を支えるシナプス結合の変化とその制御機構

    2022年

  • 恐怖記憶に起因する不適応状態からの超適応を誘起する脳領域間ネットワーク動態の解明

    2022年

  • 恐怖記憶による不適応状態からの超適応を支える脳領域間ネットワーク変化の制御機構

    新学術領域研究(研究領域提案型)  2020年04月

  • 超大規模電気生理学を用いた睡眠中のオフライン学習アルゴリズムの解析

    新学術領域研究(研究領域提案型)  2019年04月

  • 中枢神経系のサイレント・マジョリティが担う機能 ―エングラム表現への関与―

    若手研究(B)  2017年04月

奨励寄附金・助成金

  • 記憶を定着させる睡眠時の脳活動パターンの解明

    公益財団法人住友電工グループ社会貢献基金  学術・研究助成  2022年04月

  • 超大規模電気生理学記録法を用いた記憶情報表現のマルチスケール解析

    武田科学振興財団  医学系研究継続助成  2022年04月

  • 大規模電気生理学と光遺伝学を用いた脳領域横断的な情報伝達プロトコルの解析

    公益財団法人 住友財団  2022年

  • 超大規模電気生理学記録法を用いた記憶情報表現のマルチスケール解析への助成

    公益財団法人 武田科学振興財団  2022年

  • 行動選択を支える高次情報の統合メカニズムの解明

    公益財団法人アステラス病態代謝研究会  2022年

  • 速い脳波オシレーションを介した脳領域横断的な情報統合メカニズムの解明

    宮脇 寛行  2022年

  • 脳波振動カップリングが領域間の情報伝達に果たす機能的意義の解明

    大阪市立大学  戦略的研究(基盤研究)  2021年04月

  • 記憶を支える脳領域間ネットワークの変化とその制御機構の超大規模記録を用いた解析

    内藤記念科学振興財団  2020年04月

  • 脳領域間の情報統合が記憶機能に果たす役割の 超大規模電気生理学を用いた解析

    大阪市立大学  2019年04月

  • 超大規模電気生理学記録法を用いた記憶情報表現のマルチスケール解析

    武田科学振興財団  2019年04月

  • 一度きりの経験を記憶する神経メカニズムの解明

    大阪市立大学  2018年04月

  • 多点同時・高時間分解能記録法を用いた恐怖記憶の消去メカニズムの解明

    グラクソ・スミスクライン  2018年04月

  • 中枢神経系における「サイレント・マジョリティ」が情報表現に果たす役割の解析

    加藤記念バイオサイエンス振興財団  2017年04月

  • 恐怖記憶の基盤となる全脳ダイナミクスの解明

    上原記念生命科学財団  研究奨励金  2017年04月

▼全件表示

担当授業科目

  • 機能系実習

    2018年度     大学

その他

  • 職務経歴

    2016年08月 - 2017年03月

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    大阪市立大学 大学院医学研究科 特任講師