Updated on 2024/03/14
Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology
Lecturer 2022.04 - Now
School of Engineering Department of Chemistry and Bioengineering
Lecturer 2022.04 - Now
博士（工学） （ Osaka City University ）
Nanotechnology/Materials / Synthetic organic chemistry
Nanotechnology/Materials / Bio chemistry
antitumor
cyclodextrin
folic acid
anthraquinone
endocytosis
沖縄産の二枚貝の一種 Fragum sp. の共生藻より、Ca2+-ATPaseの作用を活性化する物質として、セラミドの一種であるシンビオラミドが三菱化成生命科学研の小林らによって分離された。Ca2+-ATPaseは、筋小胞体にあって、Ca2+を小胞体中に輸送し、動物の筋収縮において作用する重要な酵素である。 シンビオラミドの構造はアミノアルコール部分(Amino part)がD-エリトロ-ジヒドロスフィンゴシン、脂肪酸部分(Acid part)が2-ヒドロキシ-3-オクタデセン酸である。シンビオラミドの合成方法はいくつか報告されているが、本研究ではAmino part及びAcid part両方をL-セリンから合成した。現在、この化合物を用い、各種細胞に対するアポトーシス誘導効果等の生理活性を調べている。
リパーゼを用いたシコニン/アルカンニンの光学分割
リパーゼ
2016.04 - Now
Enhancing effect of the metabolite of 1'-acetoxychavicol acetate (ACA) on Photodynamic Therapy
Acetoxychavicol acetate, Glutathione, Photodynamic therapy Joint Research in Japan
2014.04 - Now
中国産紫根からのシコニンの抽出
シコニン Joint Research in Japan
2014.03 - 2015.03
Combination effect of S-allyl-cysteine derivative and various anti-inflammatory agents on the suppression of macrophage activation
Allylcysteine, macrophage, antiinflammation Joint Research in Japan
2013.04
Synthesis and bioactivity of the marine sphingolipids.
Marine sphingolipid, Antitumor, Apoptosis Individual
2013.04
Lipase-catalyzed Preparation of Optically Active 1'-Acetoxychavicol Acetates and their Structure-Activity Relationships in Apoptotic Activity Against Human Leukemia HL-60 Cells
Lipase, Apoptosis Joint Research in Organization
2004.04 - 2005.03
The Chemical Society of Japan
Domestic
The Society of Synthetic Organic Chemistry, Japan
Domestic
Officer of Kansai Branch The Society of Synthetic Organic Chemistry, Japan
2012.04 - Now
Lipase-catalyzed Preparation of Optically Active 1'-Acetoxychavicol Acetates and their Structure-Activity Relationships in Apoptotic Activity Against Human Leukemia HL-60 Cells
K. Miyasaka, T. Yokotani, T. Tachibana, A. Kojima-Yuasa, I. Matsui-Yuasa, K. Ogino
Bioorg. Med. Chem. 14 1811 - 1818 2007
HER-2-targeted boron neutron capture therapy using an antibody-conjugated boron nitride nanotube/β-1,3-glucan complex Reviewed
Keita Yamana, Riku Kawasaki, Kousuke Kondo, Hidetoshi Hirano, Shogo Kawamura, Yu Sanada, Kaori Bando, Anri Tabata, Hideki Azuma, Takushi ta, Yoshinori Sakurai, Hiroki Tanaka, Tomoki KTakaodama, Seiji Kawamoto, Takeshi Nagasaki, Atsushi Ikeda
Nanoscale Advances 5 3857 - 3861 2023.06
Carborane bearing pullulan nanogel-boron oxide nanoparticle hybrid for boron neutron capture therapy
Kawasaki R.
Nanomedicine: Nanotechnology, Biology, and Medicine 49 2023.04（ ISSN:15499634 ）
A new “Mitsunobu homocoupling” reaction using aldol adducts of kojic acid Reviewed
Hideki Azuma, Yasuhito Morishima, Keijin Nakaguro, Reiko Kato, Takeshi Nagasaki
Tetrahedron 94 132314 2021.06
S-allyl-glutathione suppresses liver fibrosis by inhibition of excess skewing polarization of macrophages in rats Reviewed
Minamiyama Yukiko, Takemura Shigekazu, Azuma Hideki, Osada-Oka Mayuko, Toda Michihito, Kobayashi Hikaru Keiko, Miyamoto, Ichikawa Hiroshi, Kubo Shoji
FREE RADICAL BIOLOGY AND MEDICINE 120 S133 - S133 2018.05（ ISSN:0891-5849 ）
S-allyl-glutathione improves liver fibrosis by inhibition of excess M1-or M2-polarized macrophage in rats. Reviewed
Takemura Shigekazu, Minamiyama Yukiko, Azuma Hideki, Osada-Oka Mayuko, Kubo Shoji
HEPATOLOGY 66 220A - 220A 2017.10（ ISSN:0270-9139 ）
Improved isolation procedure for shikonin from the root of the Chinese medicinal plant Lithospermum erythrorhizon and its solubilization with cyclodextrins Reviewed
Azuma Hideki, Li Jiawei, Youda Ryota, Suzuki Toshio, Miyamoto Kazuhide, Taniguchi Taizo, Nagasaki Takeshi
JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS 3 ( 2 ) 58 - 63 2016.05（ ISSN:2214-7861 ）
Anti-inflammatory effect of water-soluble complex of 1 '-acetoxychavicol acetate with highly branched beta-1,3-glucan on contact dermatitis Reviewed
Li Jiawei, Aizawa Yui, Hiramoto Keiichi, Kasahara Emiko, Tsuruta Daisuke, Suzuki Toshio, Ikeda Atsushi, Azuma Hideki, Nagasaki Takeshi
BIOMEDICINE & PHARMACOTHERAPY 69 201 - 207 2015.02（ ISSN:0753-3322 ）
Kodai Shintaro, Takemura Shigekazu, Kubo Shoji, Azuma Hideki, Minamiyama Yukiko
SOCIETY FOR FREE RADICAL RESEARCH JAPAN Journal of Clinical Biochemistry and Nutrition 0 ( 0 ) 2015（ ISSN:0912-0009 ）
The synergistic effect of 1 '-acetoxychavicol acetate and sodium butyrate on the death of human hepatocellular carcinoma cells Reviewed
Kato Rie, Matsui-Yuasa Isao, Azuma Hideki, Kojima-Yuasa Akiko
CHEMICO-BIOLOGICAL INTERACTIONS 212 1 - 10 2014.04（ ISSN:0009-2797 ）
Takemura Shigekazu, Minamiyama Yukiko, Kodai Shintaro, Shinkawa Hiroji, Tsukioka Takuma, Okada Shigeru, Azuma Hideki, Kubo Shoji
SOCIETY FOR FREE RADICAL RESEARCH JAPAN JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 53 ( 2 ) 94 - 101 2013.09（ ISSN:0912-0009 ）
The synergistic effect of 1 '-acetoxychavicol acetate and sodium butyrate on cell death of human hepatocellular carcinoma cells Reviewed
Kato Rie, Matsui-Yuasa Isao, Azuma Hideki, Kojima-Yuasa Akiko
FASEB JOURNAL 27 2013.04（ ISSN:0892-6638 ）
HVJ-E/importin-beta hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery Reviewed
Kawazu Takeshi, Kanzaki Hiroyuki, Uno Atsushi, Azuma Hideki, Nagasaki Takeshi
BIOMEDICINE & PHARMACOTHERAPY 66 ( 7 ) 519 - 524 2012.10（ ISSN:0753-3322 ）
Protein recognition of hetero-/homoleptic ruthenium(II) tris(bipyridine)s for alpha-chymotrypsin and cytochrome c Reviewed
Yamaguchi Yoshinobu, Kato Nobuo, Azuma Hideki, Nagasaki Takeshi, Ohkanda Junko
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 22 ( 6 ) 2354 - 2358 2012.03（ ISSN:0960-894X ）
Protein recognition of hetero-/homoleptic ruthenium(II) tris(bipyridine)s for α-chymotrypsin and cytochrome c
Y. Yamaguchi, N. Kato, H. Azuma, T. Nagasaki, J. Ohkanda
Bioorg. Med. Chem. Lett. 22 2354 - 2358 2012
Tumor accumulation of ε-poly-lysines-based polyamines conjugated with boron clusters
M. Umano, K. Uechi, T. Uriuda, S. Murayama, H. Azuma, A. Shinohara, Y. Liu, K. Ono, M. Kirihata, H. Yanagie, T. Nagasaki
Appl. Radiat. Isot. 69 519 - 524 2012
HVJ-E/importin-β hybrid vector for overcoming cytoplasmic and nuclear membranes as double barrier for non-viral gene delivery
T. Kawazu, H. Kanzaki, A. Uno, H. Azuma, T. Nagasaki
Biomed. Pharmacother. 66 519 - 524 2012
Tumor accumulation of epsilon-poly-lysines-based polyamines conjugated with boron clusters Reviewed
Umano Masayuki, Uechi Kazuhiro, Uriuda Takatoshi, Murayama Sayuri, Azuma Hideki, Shinohara Atsuko, Liu Young, Ono Koji, Kirihata Mitsunori, Yanagie Hironobu, Nagasaki Takeshi
APPLIED RADIATION AND ISOTOPES 69 ( 12 ) 1765 - 1767 2011.12（ ISSN:0969-8043 ）
Biological activity of water-soluble inclusion complexes of 1 '-acetoxychavicol acetate with cyclodextrins Reviewed
Azuma Hideki, Aizawa Yui, Higashitani Nao, Tsumori Takashi, Kojima-Yuasa Akiko, Matsui-Yuasa Isao, Nagasaki Takeshi
BIOORGANIC & MEDICINAL CHEMISTRY 19 ( 12 ) 3855 - 3863 2011.06（ ISSN:0968-0896 ）
Azuma Hideki, Aizawa Yui, HIgashitani Nao, Kojima Akiko, Nagasaki Takeshi
Association of Research for Host-Guest and Supramolecular Chemistry, Abstracts of Papers: Host-Guest Chemistry Symposium 2011 ( 0 ) 33 - 33 2011
1 '-Acetoxychavicol Acetate Enhances the Phase II Enzyme Activities via the Increase in Intranuclear Nrf2 Level and Cytosolic p21 Level Reviewed
Yaku Keisuke, Matsui-Yuasa Isao, Azuma Hideki, Kojima-Yuasa Akiko
AMERICAN JOURNAL OF CHINESE MEDICINE 39 ( 4 ) 789 - 802 2011（ ISSN:0192-415X ）
1'-Acetoxychavicol acetate enhances the phase II enzyme activities via the increase in intranuclear Nrf2 level and cytosolic p21 level
K. Yaku, I. Matsui-Yuasa, H. Azuma, A. Kojima-Yuasa
Am. J. Chin. Med. 39 789 - 802 2011
Biological activity of water-soluble inclusion complexes of 1'-acetoxychavicol acetate with cyclodextrins
H. Azuma, Y. Aizawa, N. Higashitani, T. Tsumori, A. Kojima-Yuasa, I. Matsui-Yuasa, T. Nagasaki
Bioorg. Med. Chem. 19 855 - 3863 2011
Comparison of glutathione reductase activity and the intracellular glutathione reducing effects of 13 derivatives of 1 '-acetoxychavicol acetate in Ehrlich ascites tumor cells Reviewed
Xu Shenghui, Kojima-Yuasa Akiko, Azuma Hideki, Kennedy David Opare, Konishi Yotaro, Matsui-Yuasa Isao
CHEMICO-BIOLOGICAL INTERACTIONS 185 ( 3 ) 235 - 240 2010.05（ ISSN:0009-2797 ）
Enhanced internalization and endosomal escape of dual-functionalized poly(ethyleneimine)s polyplex with diphtheria toxin T and R domains Reviewed
Kakimoto Shinji, Tanabe Toshizumi, Azuma Hideki, Nagasaki Takeshi
BIOMEDICINE & PHARMACOTHERAPY 64 ( 4 ) 296 - 301 2010.04（ ISSN:0753-3322 ）
Structure-activity relationships of (1' S)-acetoxychavicol acetate for the decrease in intracellular glutathione level in Ehrlich ascites tumor cells Reviewed
Matusi-Yuasa Isao, Xu Shenghui, Kojima-Yuasa Akiko, Azuma Hideki, Kennedy David Opare
FASEB JOURNAL 24 2010.04（ ISSN:0892-6638 ）
Enhanced Internalization and Endosomal Escape of Dual-Functinalized Poly(ethylenimine)s Polyplex with Diphtheria toxin T and R Domains
S. Kakimoto, T. Tanabe, H. Azuma, T. Nagasaki
Biomed. Pharmacother. 64 296 - 301 2010
Comparison of glutathione reductase activity and the intracellular glutathione reducing effects of 13 derivatives of 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells
S. Xu, A. Kojima-Yuasa, H. Azuma, D. O. Kennedy, Y. Konishi, I. Matsui-Yuasa
Chem. Biol. Interact. 185 235 - 240 2010
(1\#8217;S)-Acetoxychavicol acetate and its enantiomer cause the inhibition of tumor cell growth via different mechanisms Reviewed
Xu Shenghui, Kojima-Yuasa Akiko, Azuma Hideki, Matsui-Yuasa Isao
CANCER RESEARCH 69 2009.05（ ISSN:0008-5472 ）
The conjugation of diphtheria toxin T domain to poly(ethylenimine) based vectors for enhanced endosomal escape during gene transfection Reviewed
Kakimoto Shinji, Hamada Tsutomu, Komatsu Yuuki, Takagi Masahiro, Tanabe Toshizumi, Azuma Hideki, Shinkai Seiji, Nagasaki Takeshi
BIOMATERIALS 30 ( 3 ) 402 - 408 2009.01（ ISSN:0142-9612 ）
Azuma Hideki, Yoshida Yuuka, Paul Dharam, Shinoda Satoshi, Tsukube Hiroshi, Nagasaki Takeshi
Association of Research for Host-Guest and Supramolecular Chemistry, Abstracts of Papers: Host-Guest Chemistry Symposium 2009 ( 0 ) 13 - 13 2009
Cytochrome c-binding "proteo-dendrimers" as new types of apoptosis inhibitors working in HeLa cell systems Reviewed
Azuma Hideki, Yoshida Yuuka, Paul Dharam, Shinoda Satoshi, Tsukube Hiroshi, Nagasaki Takeshi
ORGANIC & BIOMOLECULAR CHEMISTRY 7 ( 8 ) 1700 - 1704 2009（ ISSN:1477-0520 ）
Cytochrome c-binding "proteo-dendrimers" as new types of apoptosis inhibitors working in HeLa cell systems
Y. Yoshida, D. Paul, S. Shinoda, H. Tsukube, T. Nagasaki
Org. Biomol. Chem. 7 1700 - 1704 2009
The conjugation of diphtheria toxin T domain to poly(ethylenimine) based vectors for enhanced endosomal escape during gene transfection
S. Kakimoto, T. Hamada, Y. Komatsu, M. Takagi,T. Tanabe, H. Azuma, S. Shinkai, T. Nagasaki
Biomaterials 30 402 - 408 2009
(1'S)-acetoxychavicol acetate and its enantiomer inhibit tumor cells proliferation via different mechanisms Reviewed
Xu Shenghui, Kojima-Yuasa Akiko, Azuma Hideki, Huang Xuedan, Norikura Toshio, Kennedy David Opare, Matsui-Yuasa Isao
CHEMICO-BIOLOGICAL INTERACTIONS 172 ( 3 ) 216 - 223 2008.04（ ISSN:0009-2797 ）
Xu Shenghui, Yuasa-Kojima Akiko, Azuma Hideki, Yuasa-Matsui Isao
Osaka City University, Journal of human life science 7 13 - 20 2008（ ISSN:13486926 ）
(1’S)-Acetoxychavicol Acetate and its Enantiomer Inhibit Tumor Cells Proliferation via Different Mechanisms
S. Xu, A. Kojima-Yuasa, H. Azuma, X. Huang, T. Norikura, D. O. Kennedy, I. Matsui-Yuasa
Chem. Biol. Interact. 172 216 - 223 2008
Short-chain 3-ketoceramides, strong apoptosis inducers against human leukemia HL-60 cells Reviewed
Azuma Hideki, Ijichi So, Kataoka Mayuko, Masuda Akira, Izumi Takayuki, Yoshimoto Tetsuya, Tachibana Taro
BIOORGANIC & MEDICINAL CHEMISTRY 15 ( 8 ) 2860 - 2867 2007.04（ ISSN:0968-0896 ）
Short-chain 3-Ketoceramides, strong apoptosis inducers against human leukemia HL-60 Cells
S. Ijichi, M. Kataoka, A. Masuda, T. Izumi, T. Yoshimoto, T. Tachibana
Bioorg. Med. Chem 15 2860 - 2867 2007
Lipase-catalyzed preparation of optically active 1 '-acetoxychavicol acetates and their structure-activity relationships in apoptotic activity against human leukemia HL-60 cells Reviewed
Azuma H, Miyasaka K, Yokotani T, Tachibana T, Kojima-Yuasa A, Matsui-Yuasa I, Ogino K
BIOORGANIC & MEDICINAL CHEMISTRY 14 ( 6 ) 1811 - 1818 2006.03（ ISSN:0968-0896 ）
(3Z)-2-Acetylamino-3-octadecen-1-ol as A Potent Apoptotic Agent Against HL-60 Cells
Hayato Niiro, Hideki Azuma, Sinsuke Tanago, Taro Tachibana, Kenji Ogino
Bioorg. Med. Chem. 12 45 - 52 2004
Total Syntheses of Symbioramide Derivatives from L-Serine and their Antileukemic Activities
H. Azuma, R. Takao, H. Niiro, K. Shikata, S. Tamagaki
The Journal of Organic Chemistry 68 ( 7 ) 2790 - 2797 2003
Synthesis and Potent Antileukemic Activities of N-Lactyl-sphingosine and N-Lactyl-dihydrosphingosine
Journal of Medicinal Chemistry 46 3445–3447 2003
Apoptotic Activities of C2-Ceramide and C2-Dihydroceramide Homologues Against HL-60 Cells
Bioorganic and Medicinal Chemistry 11 2723–2728 2003
Synthesis of Non-natural C2-Homo-Ceramide and its Apoptotic Activity against HL-60 Cells
Bioorganic and Medicinal Chemistry Letters 13 613–616 2003
Synthesis of Novel and Non-natural Ceramide Analogues Derived from L-glutamic Acid
Tetrahedron 58 5803–5809 2002
Stereospecific Total Syntheses of Sphingosine and Its Analogues from L-Serine
Journal of Organic Chemistry 65 3538 - 3541 2000
Photodynamic effect of coumaryl alcohol derivative-modified 5-aminolevulinic acid Domestic conference
2024.03
糖鎖抗原用の糖セラミドLex-C12Lの合成 Domestic conference
竹林尚志、東秀紀、長崎健
第43回有機合成学会若手セミナー 2023.08
4-((E)-3-Hydroxyprop-1-enyl)phenyl acetate修飾ALAを基にした メラノーマ治療薬の開発 Domestic conference
松枝蒼弥、東秀紀、長崎健
第43回有機合成学会若手セミナー 2023.08 有機合成化学協会関西支部
Design and synthesis of new chiral derivatization agent for simultaneous analysis of D- and L-amino acids Domestic conference
2023.03
キラル誘導体化試薬の開発とD,L-アミノ酸一斉分析への応用 Domestic conference
佐藤 俊, 佐々木 一謹, 東 秀紀
新アミノ酸分析研究会 第12回学術講演会 2022.12 新アミノ酸分析研究会
Development of chiral derivatizing reagent: Application to simultaneous analysis of D,L-amino acids Domestic conference
2022.09 Institute for Advanced Biosciences, Keio University
ガレクチン-3及びアシアロ糖タンパクレセプターをターゲットとしたラクトース提示型シクロデキストリンベシクルの作製 Domestic conference
立石奈央, 東 秀紀, 長崎 健
第18回 ホスト-ゲスト・超分子化学シンポジウム 2021.06
コウジ酸アルドール付加体を用いた光延条件下における新規ホモカップリング反応 Domestic conference
東 秀紀, 森島康仁, 中畔慶人, 加藤麗子, 長崎 健
日本化学会第101春季年会 2021.03
Preparation and intracellular migration of self-assembled and folic-acid modified vesicles composed of anthraquinone-bearing cyclodextrin and 1’-acetoxychavicol acetate Domestic conference
Hideki Azuma, Chisa Fukuda, Akiko Kojima, Takeshi Nagasaki
The 45th Symposium on Biomolecular Science 2018.06
Application of self-assembled vesicles prepared from anthraquinone-modified cyclodextrins as carriers of 1’-acetoxychavicol acetate and presentation of folic acid on the surfaces Domestic conference
Hideki Azuma, Chisa Fukuda, Takeshi Nagasaki
The 98th CSJ Annual Meeting 2018.03
Study on melanoma selective uptake of kojic acid using its fluorescent labeled analogues Domestic conference
Yasuhito Morishima, Takuya Oofuji, Hideki Azuma, Takeshi Nagasaki
The 47th Congress of Heterocyclic Chemistry 2017.10
アントラキノン修飾シクロデキストリンへの葉酸レセプターをターゲットにした細胞選択性 の付与 Domestic conference
東秀紀, 福田千紗, 長崎健
第33回日本DDS学会学術集会 2017.07
Lipase-catalyzed optical resolution of shikonin/alkannin Domestic conference
Hideki AZUMA, kyosuke Enomoto, Toshio SUZUKI, Taizo TANIGUCHI, Takeshi NAGASAKI
The Society of Physical Organic Chemistry, Japan 2017.06
Preparation of self-assembled vesicles from anthraquinone-modified cyclodextrin/1’-acetoxychavicol acetate complexes and presentation of folic acids on the vesicle surfaces Domestic conference
Chisa Fukuda, Hideki AZUMA, Takeshi NAGASAKI
The Society of Physical Organic Chemistry, Japan 2017.06
1’―アセトキシチャビコールアセテート／シクロデキストリン複合体の抗炎症効果 Domestic conference
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第33回 シクロデキストリンシンポジウム 2016.09
アントラキノン修飾β-シクロデキストリンより調製した1'-acetoxychavicol acetateに対するキャリアとしての応用 Domestic conference
-
第33回シクロデキストリンシンポジウム 2016.09
1’-アセトキシチャビコールアセテート/シクロデキストリン複合体の抗炎症効果 Domestic conference
-
第14回ホスト・ゲスト化学シンポジウム 2016.06
Preparation of the water-soluble inclusion complex of coumaryl alcohol derivative with 2-hydroxypropyl-beta-cyclodextrin and its enhancing effect on photodynamic therapy Domestic conference
Host−Guest Chemistry Symposium 2016 2016.06
アントラキノン修飾シクロデキストリンより調製した自己集積性ベシクルの 1’-acetoxychavicol acetate に対するキャリアとしての応用(阪市大 Domestic conference
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第14回ホスト・ゲスト化学シンポジウム 2016.06
Enhancing effect of coumaryl alcohol derivative on Photodynamic Therapy Domestic conference
2016.03
Anti-inflammatory effect of water-soluble inclusion complexes of 1'-acetoxychavicol acetate with cyclodextrins Domestic conference
2015.06
Enhancing effect of the metabolite of 1'-acetoxychavicol acetate (ACA) on photodynamic therapy Domestic conference
2015.03
Enhancing effect of the metabolite of 1'-acetoxychavicol acetate (ACA) on mitochondrial apoptosis Domestic conference
The 93rd Annual Meeting of The Chemical Society of Japan 2014.03
玉造黒門越瓜に含まれる新規アルコール性肝障害抑制物質の同定 1'-Acetoxychavicol acetateのシクロデキストリンによる水溶化及び抗炎症効果に関する研究 Domestic conference
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第33回有機合成若手セミナー 2013.08
ミトコンドリア経由アポトーシスを制御する新規化合物の探索及び水溶化の検討 Domestic conference
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第29回日本DDS学会学術集会 2013.07
Anti-inflammation effect of water-soluble inclusion complexes of 1'-acetoxychavicol acetate with cyclodextrins Domestic conference
The 93rd Annual Meeting of The Chemical Society of Japan 2013.03
低酸素細胞をターゲットとした新規シクロデキストリンキャリアの合成 アポトーシスを制御する新規化合物の探索 Domestic conference
-
第32回有機合成若手セミナー 2012.11
Preparation and apoptogenic potency of Mcl-1 siRNA-encapsulated liposome containing short-chain 3-ketoceramide International conference
The International Symposium on Nucleic Acid Chemistry 2011.11
Mcl-1 siRNA を包埋したケトセラミドリポソームの作製及びアポトーシス誘導活性評価 Domestic conference
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アンチセンス・遺伝子・デリバリー シンポジウム2011 2011.09
抗体作製におけるα-ガラクトシルセラミド類含有リポソームのアジュバント効果 Domestic conference
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第5回バイオ関連化学シンポジウム 2011.09
シクロデキストリンを用いた水溶性1’-Acetoxychavicol Acetate複合体の作製及び抗腫瘍効果に関する研究 Domestic conference
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第7回ホスト・ゲスト化学シンポジウム 2011.05
2-(2-オキソ-4-置換ピペラジニル)シクロアルキルカルバメート化合物又はその塩、当該化合物を用いる鏡像異性体の分析方法
佐藤 俊, 佐々木 一謹, 東 秀紀
白血球活性化抑制剤
竹村 茂一，岡 真優子，新川 寛二，新川 寛二，東 秀紀，南山 幸子
水難溶性薬理活性物質の薬理活性を維持しながら水溶性を付与する方法
鈴木 利雄、植田 秀昭、長崎 健，東 秀紀、小島 明子、湯浅 勲
抗肥満剤
湯浅 勲、小島 明子、東 秀紀
コラーゲン産生促進剤
小島 明子、東 秀紀
シトクロムｃ捕捉型アポトーシス抑制剤
長崎 健、東 秀紀、築部 浩、篠田哲史
コラーゲン産生促進剤
湯浅 勲、小島 明子、東 秀紀
Synthese of the bioactive compounds of sphingolipids
2001.1-
コウジ酸修飾ホウ素クラスターを用いた中性子捕捉療法のメラノーマへの適用を目指した基礎研究
未設定 2011.07
チャビコールフラグメントを基にした新規コラーゲン産生促進剤の開発
未設定 2010.10
化学バイオ工学科の教育では、生物や生命システムを理解するだけでなく、化学や物理学、情報処理などの広い範囲の工学的な知識をもち、社会や産業に貢献できる新しい技術やものを生み出せる人材の育成が目的となる。従って、生物学のみならず、化学、物理学にまたがる広範な教育が必要とされ、講座全体で効率の良い教育方法を考えていかなければならない。現在、学部では分析化学Ⅱ及び情報バイオ演習を担当しており、分析化学Ⅱでは様々な分析機器から得られるデータの読み取り方について講義し、情報バイオ演習では今日の研究者に必須のパソコンを用いた情報処理能力の向上を目指した教育を行っている。これらの講義・演習により、基礎知識やプレゼンテーション能力に加え、得られたデータから次になすべき実験を的確に考えるといった研究遂行能力の高い人材を育成したいと考えている。
化学バイオ工学実験B
2024 Weekly class Undergraduate
化学バイオ工学演習
2024 Weekly class Undergraduate
生物化学基礎
2024 Weekly class Undergraduate
生物有機化学
2024 Weekly class Undergraduate
卒業研究Ⅰ
2024 Intensive lecture Undergraduate
化学バイオ工学演習Ａ
2024 Intensive lecture Undergraduate
分析化学Ⅱ
2024 Intensive lecture Undergraduate
バイオ工学実験Ⅰ
2024 Weekly class Undergraduate
情報バイオ演習
2024 Intensive lecture Undergraduate
化学バイオ工学特論Ⅰ
2024 Intensive lecture Undergraduate
化学バイオ工学概論
2024 Intensive lecture Undergraduate
Exercises in Bioinformatics
2023 Weekly class Undergraduate
Analytical chemistry II
2023 Weekly class Undergraduate
情報バイオ演習
2022 Weekly class Undergraduate
分析化学Ⅱ
2021 Weekly class Undergraduate
バイオ工学実験Ⅰ
2021 Weekly class Undergraduate
化学バイオ工学演習A
2021 Weekly class Undergraduate
情報バイオ演習
2021 Weekly class Undergraduate
バイオ工学実験Ⅰ
2020 Undergraduate
化学バイオ工学演習A
2020 Undergraduate
情報バイオ演習
2020 Undergraduate
分析化学Ⅱ
2020 Undergraduate
バイオ工学実験Ⅰ
2019 Undergraduate
Exercises in Applied Chemistry and Bioengineering A
2019 Undergraduate
IT Exercises in Bioengineering
2019 Undergraduate
Analytical Chemistry II
2019 Undergraduate
バイオ工学実験Ⅰ
2018 Undergraduate
IT Exercises in Bioengineering
2018 Undergraduate
Exercises in Applied Chemistry and Bioengineering A
2018 Undergraduate
Analytical Chemistry II
2018 Undergraduate
バイオ工学実験Ⅰ
2017 Undergraduate
Analytical Chemistry II
2017 Undergraduate
IT Exercises in Bioengineering
2017 Undergraduate
Exercises in Applied Chemistry and Bioengineering A
2017 Undergraduate
分析化学Ⅱ
2016 Undergraduate
情報バイオ演習
2016 Undergraduate
化学バイオ工学演習A
2016 Undergraduate
バイオ工学実験Ⅰ
2016 Undergraduate
分析化学Ⅱ
2015 Undergraduate
情報バイオ演習
2015 Undergraduate
バイオ工学実験Ⅰ
2015 Undergraduate
化学バイオ工学演習Ⅱ
2015 Undergraduate
技術と生命（第9回＆第10回）
2015 Undergraduate
分析化学Ⅱ
2014 Undergraduate
バイオ工学実験Ⅰ
2014 Undergraduate
情報バイオ演習
2014 Undergraduate
分析化学Ⅱ
2013 Undergraduate
バイオ工学実験Ⅰ
2013 Undergraduate
情報バイオ演習
2013 Undergraduate
分析化学Ⅱ
2012 Undergraduate
情報バイオ演習
2012 Undergraduate
バイオ工学実験Ⅰ
2012 Undergraduate
情報バイオ演習
2011 Undergraduate
分析化学Ⅱ
2011 Undergraduate
バイオ工学実験Ⅰ
2011 Undergraduate
工学部FD集会 2023
工学部FD集会 2022
FD活動への貢献 2011
2022
Number of instructed the graduation thesis：2 Number of graduation thesis reviews：2
[Number of instructed the Master's Program] (previous term)：0 [Number of instructed the Master's Program] (letter term)：0
[Number of master's thesis reviews] (chief)：0 [Number of master's thesis reviews] (vice-chief)：0
[Number of doctoral thesis reviews] (chief)：0 [Number of doctoral thesis reviews] (vice-chief)：0
2021
Number of instructed the graduation thesis：2 Number of graduation thesis reviews：2
[Number of instructed the Master's Program] (previous term)：0
[Number of master's thesis reviews] (chief)：0 [Number of master's thesis reviews] (vice-chief)：0
[Number of doctoral thesis reviews] (chief)：0 [Number of doctoral thesis reviews] (vice-chief)：0
2020
Number of instructed the graduation thesis：3 Number of graduation thesis reviews：3
[Number of instructed the Master's Program] (previous term)：0 [Number of instructed the Master's Program] (letter term)：0
[Number of master's thesis reviews] (chief)：0 [Number of master's thesis reviews] (vice-chief)：0
[Number of doctoral thesis reviews] (chief)：0 [Number of doctoral thesis reviews] (vice-chief)：0
2011
Number of instructed the graduation thesis：3 Number of graduation thesis reviews：3
[Number of instructed the Master's Program] (previous term)：0 [Number of instructed the Master's Program] (letter term)：0
[Number of master's thesis reviews] (chief)：0 [Number of master's thesis reviews] (vice-chief)：0
[Number of doctoral thesis reviews] (chief)：0 [Number of doctoral thesis reviews] (vice-chief)：0
論文査読
Role(s)： Peer review
2022.04 - 2023.03
2022
Original item：危険物保安監督者（工学研究科危険物倉庫）
2021
Original item：危険物保安監督者(工学研究科危険物倉庫)
Job Career
2007.04 - Now
Job Career
2002.04 - 2007.03
Job Career
1998.10 - 2002.03