Updated on 2025/01/07

写真a

 
NISHIMURA Takahiro
 
Organization
Graduate School of Science Department of Chemistry Professor
School of Science Department of Chemistry
Title
Professor
Affiliation
Institute of Science

Position

  • Graduate School of Science Department of Chemistry 

    Professor  2022.04 - Now

  • School of Science Department of Chemistry 

    Professor  2022.04 - Now

Degree

  • Doctor (Engineering) ( Kyoto University )

Research Areas

  • Nanotechnology/Materials / Synthetic organic chemistry

  • Nanotechnology/Materials / Green sustainable chemistry and environmental chemistry

Research Interests

  • organic chemistry

  • catalysis

  • asymmetric synthesis

  • Transition-Metal-Catalysts

  • Atom Econimy

  • Green Chemistry

Research subject summary

  • Transition metal-catalyzed functionalization of aromatic compounds via C-H bond activation has realized the step-economy synthesis of useful compounds. In particular, an ortho-selective functionalization has been achieved by use of directing groups, and in the past few decades, many catalytic systems for the C-H bond activation have been developed. We are interested in development of atom-economical organic transformations to realize stereoselective synthesis of useful organic molecules.

Professional Memberships

  • 近畿化学協会

      Domestic

  • 有機合成化学協会

      Domestic

  • American Chemical Society

      Overseas

  • 日本化学会

      Domestic

Awards

  • 宇部興産学術振興財団第52回学術奨励賞

    2012  

  • Banyu Chemist Award

    2010  

  • Incentive Award in Synthetic Organic Chemistry, Japan

    2008  

  • 有機合成化学協会東レ研究企画賞

    2003  

Job Career (off-campus)

  • 京都大学   大学院理学研究科化学専攻   講師

    2005.04 - 2017.03

  • 京都大学   大学院工学研究科物質エネルギー化学専攻   助手

    2001.04 - 2005.03

  • 日本学術振興会特別研究員   DC2

    1999.01 - 2001.03

  • 出光興産株式会社   技術職

    1996.04 - 1997.06

Education

  • Kyoto University   Doctor's Course   Graduated/Completed

    1997.10 - 2001.03

  • Kyoto University   Master's Course   Graduated/Completed

    1994.04 - 1996.03

  • Kyoto University     Graduated/Completed

    1989.04 - 1994.03

Papers

  • Iridium/chiral phosphoramidite-olefin complex-catalysed enantioselective [3+2] annulation of ortho-ketoarylboron compounds with conjugated dienes Reviewed

    Yabe R.

    Chemical Communications   60 ( 90 )   13211 - 13214   2024.10( ISSN:13597345

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d4cc04238g

  • Iridium-catalyzed asymmetric addition of imides to alkenes Reviewed

    Kentaro Yamakawa, Kana Sakamotoa, Takahiro Nishimura

    Chemical Communications   59   12871 - 12874   2023.10

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    Authorship:Last author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1039/D3CC04406H

    Other URL: https://pubs.rsc.org/en/content/articlelanding/2023/cc/d3cc04406h

  • Ruthenium-catalysed <i>N</i>-alkylation of anilines with primary carbohydrate alcohols <i>via</i> borrowing hydrogen strategy Reviewed

    Kouki Tsuge, Shunnichi Kubota, Kana Sakamoto, Kenji Kitayama, Takahiro Nishimura

    CHEMICAL COMMUNICATIONS   59 ( 46 )   7052 - 7055   2023.06( ISSN:1359-7345 ( eISSN:1364-548X

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    Publishing type:Research paper (scientific journal)  

    Ruthenium-catalysed N-alkylation of anilines with sugar derivatives proceeded via the borrowing hydrogen strategy. Primary carbohydrate alcohols were successfully applied to N-alkylation of aniline derivatives to give the corresponding aminosugars in high yields.

    DOI: 10.1039/d3cc01931d

  • Iridium-Catalyzed Branch-Selective and Enantioselective C2-Alkylation of N-Benzimidazolyl Indoles Reviewed

    Kentaro Yamakawa, Takahiro Nishimura

    ADVANCED SYNTHESIS & CATALYSIS   365 ( 12 )   2013 - 2017   2023.06( ISSN:1615-4150 ( eISSN:1615-4169

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    Publishing type:Research paper (scientific journal)  

    Iridium-catalyzed enantioselective C2-alkylation of indole derivatives with terminal alkenes proceeded to give branched alkylation products with high enantioselectivity (39-99% yields, 20-91% ee). The reaction of indole derivatives having an N-substituted benzimidazolyl as a directing group gave the branch-selective alkylated products. Styrene derivatives and allylsilanes were good substrates displaying high enantioselectivity. The directing group was readily removed in several ways.

    DOI: 10.1002/adsc.202300370

  • Synthesis of Chiral Spiro[45]decadienones via Chirality-Transferring Oxidative Intramolecular Cyclization of Allenylsilane-Tethered Phenols Reviewed

    Kishimoto R.

    Synthesis (Germany)   55 ( 17 )   2713 - 2729   2023.03( ISSN:00397881

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/a-2075-3258

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Books and Other Publications

  • ロジウム,有機合成実験法ハンドブック第2版

    西村 貴洋( Role: Sole author ,  608–627)

    有機合成化学協会  2015 

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    Book type:Scholarly book

  • Preparation of Fluoroalkylated-Pyridines

    NISHIMURA Takahiro( Role: Sole author)

    Handbook on Fluorous Chemistry; Eds. J. A. Gladysz, D. P. Curran, I. H. Horváth, Wiley-VCH  2004 

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    Book type:Scholarly book

MISC

Presentations

  • Ir-Catalyzed Asymmetric [3+2] Annulation of ortho-Keto Arylboron Reagents with 1,3-Dienes International conference

    Ryota Yabe, Takahiro Nishimura

    The 15th International Kyoto Conference on New Aspects of Organic Chemistry  2023.11 

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    Presentation type:Poster presentation  

    Venue:Rihga Royal Hotel KYOTO  

  • Iridium-Catalyzed Branch-Selective and Enantioselective Alkylation of N-Benzimidazolyl Indoles International conference

    Kentaro Yamakawa, Takahiro Nishimura

    The 15th International Kyoto Conference on New Aspects of Organic Chemistry  2023.11 

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    Presentation type:Poster presentation  

    Venue:Rihga Royal Hotel KYOTO  

  • Synthesis of Chiral Spiro[4.5]decadienones via Chirality-transferring Oxidative Intramolecular Cyclization of Allenylsilane-tethered Phenols International conference

    Ryoma Kishimoto, Yuka Iwakiri, Kazuhiko Sakaguchi, Takahiro Nishimura

    The 15th International Kyoto Conference on New Aspects of Organic Chemistry  2023.11 

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    Presentation type:Poster presentation  

    Venue:Rihga Royal Hotel KYOTO  

  • Tuning of Directing Groups for Iridium-Catalyzed Enantioselective α-C–H Alkylation of Pyrrolidine Derivatives International conference

    Daisuke Yamauchi, Kentaro Yamakawa, Takahiro Nishimura

    The 15th International Kyoto Conference on New Aspects of Organic Chemistry  2023.11 

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    Presentation type:Poster presentation  

    Venue:Rihga Royal Hotel KYOTO  

  • アレニルシランが連結したジエノンの分子内環化反応 Domestic conference

    岩切 夕香,岸本 遼真,坂口 和彦,西村 貴洋

    第13回 CSJ化学フェスタ2023  2023.10  日本化学会

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    Presentation type:Poster presentation  

    Venue:タワーホール船堀  

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Grant-in-Aid for Scientific Research

  • 炭素-水素結合活性化を起点とする含ケイ素環式化合物の立体選択的合成法の開発

    Grant-in-Aid for Scientific Research(C)  2026

  • 炭素-水素結合活性化を起点とする含ケイ素環式化合物の立体選択的合成法の開発

    Grant-in-Aid for Scientific Research(C)  2025

  • 炭素-水素結合活性化を起点とする含ケイ素環式化合物の立体選択的合成法の開発

    Grant-in-Aid for Scientific Research(C)  2024

  • 炭素-水素結合の立体選択的付加反応を利用した新反応プロセスの開発

    Grant-in-Aid for Scientific Research(B)  2019.04

  • Development of Stereoselective Hydrofuctionalizations

    Grant-in-Aid for Scientific Research(B)  2015.04

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Outline of education staff

  • 全学共通科目:基礎有機化学B
    専門科目:有機化学3,化学実験Ⅲ,化学実験S,特別研究
    大学院講義:創成分子科学演習,機能分子科学演習,化学前期特別研究II,創成分子科学ゼミナール,機能分子化学ゼミナール,後期特別研究,研究企画ゼミナール,有機金属化学特論,化学特別演習1A,1B,化学特別研究1A,1B,化学特別演習3A,3B,化学特別研究3A,3B

Charge of on-campus class subject

  • 化学実験1

    2024   Weekly class   Undergraduate

  • 化学特別演習2A

    2024   Intensive lecture   Graduate school

  • 化学特別演習1A

    2024   Intensive lecture   Graduate school

  • 化学特別研究2A

    2024   Intensive lecture   Graduate school

  • 化学特別研究1A

    2024   Intensive lecture   Graduate school

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Charge of off-campus class subject

  • 物質科学特論II

    2023.09
    Institution:Okayama Prefectural University

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    Level:Postgraduate  Country:Japan

Number of papers published by graduate students

  • 2022

    Number of graduate students presentations:5

Number of instructed thesis, researches

  • 2022

    Number of instructed the graduation thesis:Number of graduation thesis reviews:2

    [Number of instructed the Master's Program] (previous term):[Number of instructed the Master's Program] (letter term):3

    [Number of master's thesis reviews] (chief):[Number of master's thesis reviews] (vice-chief):3

    [Number of doctoral thesis reviews] (chief):[Number of doctoral thesis reviews] (vice-chief):0

Social Activities ⇒ Link to the list of Social Activities

  • 有機金属化学セミナー

    Role(s): Lecturer

    Type: Seminar, workshop

    近畿化学協会  2019.06

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    Audience: University students, Graduate students, Teachers, Researchesrs, General public, Company

  • 化学セミナー/先端科学研修

    Role(s): Lecturer

    Type: Seminar, workshop

    大阪市立大学理学部  大阪市立大学  2018.07

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    Audience: High school students, General public