Updated on 2023/11/28

写真a

 
KAGE-NAKADAI Eriko
 
Organization
Graduate School of Human Life and Ecology Division of Human Life and Ecology Professor
School of Human Life and Ecology Department of Nutrition
Title
Professor
Affiliation
Institute of Human Life and Ecology
Other name(s)
Eriko KAGE

Position

  • Graduate School of Human Life and Ecology Division of Human Life and Ecology 

    Professor  2022.04 - Now

  • School of Human Life and Ecology Department of Nutrition 

    Professor  2022.04 - Now

Degree

  • 博士(薬学) ( The University of Tokyo )

Research Areas

  • Humanities & Social Sciences / Family and consumer sciences, and culture and living

  • Life Science / Bacteriology

  • Life Science / Physiology

  • Life Science / Clinical pharmacy

Professional Memberships

  • American Society for Microbiology

      Overseas

  • 日本農芸化学会

      Domestic

  • 日本生理学会

      Domestic

  • 日本栄養・食糧学会

      Domestic

  • 日本細菌学会

      Domestic

  • 日本分子生物学会

      Domestic

  • 日本薬学会

      Domestic

  • 日本食品微生物学会

      Domestic

▼display all

Committee Memberships (off-campus)

  • 参与   日本栄養・食糧学会  

    2022.04 - Now 

  • 評議員   日本食品微生物学会  

    2020.04 - Now 

  • 第76回大会実行委員   日本栄養・食糧学会  

    2020.04 - Now 

  • 関西支部評議員   日本細菌学会  

    2018.01 - Now 

  • 第39回学術総会実行委員   日本食品微生物学会  

    2017.10 - 2018.12 

  • 評議員   日本生理学会  

    2012 - Now 

▼display all

Job Career (off-campus)

  • 東京女子医科大学医学部   講師

    2012.04 - 2014.01

  • 東京女子医科大学医学部   助教

    2007.04 - 2012.03

  • 三共株式会社(現・第一三共株式会社)   研究員

    2004.04 - 2007.02

Education

  • The University of Tokyo   Doctor's Course   Graduated/Completed

    2001.04 - 2004.03

  • Kyushu University   Master's Course   Graduated/Completed

    1999.04 - 2001.03

  • Kyushu University     Graduated/Completed

    1995.04 - 1999.03

Papers

  • Improvement of Locomotion Caused by Lactococcus lactis subsp. lactis in the Model Organism Caenorhabditis elegans. Reviewed

    Ali MS, Ahmed S, Takeuchi S, Wada T, Kage-Nakadai E

    Nutrients   15 ( 20 )   2023.10

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/nu15204482

    PubMed

  • Impacts of Bacillus subtilis var. Natto on the lifespan and stress resistance of caenorhabditis elegans. Reviewed

    Teramoto N, Sato K, Wada T, Nishikawa Y, Kage-Nakadai E

    Journal of applied microbiology   2023.04( ISSN:1364-5072

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/jambio/lxad082

    PubMed

  • Determinants of subtype-selectivity of the anthelmintic paraherquamide A on Caenorhabditis elegans nicotinic acetylcholine receptors. Reviewed International coauthorship

    Koizumi W, Otsubo S, Furutani S, Niki K, Takayama K, Fujimura S, Maekawa T, Koyari R, Ihara M, Kai K, Hayashi H, Ali MS, Kage-Nakadai E, Sattelle DB, Matsuda K.

    Mol Pharmacol   MOLPHARM ( -AR )   2022 - -000601   2023.03

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1124/molpharm.122.000601.

  • Avoidance behavior and experience-dependent tolerance in response to bitter compounds in Caenorhabditis elegans. Reviewed

    Ishikawa S, Iida C, Takezawa Y, Chiba K, Kage-Nakadai E

    Bioscience, biotechnology, and biochemistry   87 ( 3 )   314 - 319   2023.02( ISSN:0916-8451

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/bbb/zbac200

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  • High-performance optical control of GPCR signaling by bistable animal opsins MosOpn3 and LamPP in a molecular property-dependent manner. Reviewed

    Koyanagi M, Shen B, Nagata T, Sun L, Wada S, Kamimura S, Kage-Nakadai E, Terakita A.

    Proc Natl Acad Sci U S A   119 ( 48 )   e220434111   2022.11

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1073/pnas.2204341119.

  • Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples Reviewed International coauthorship

    Oshimi K, Nishimura Y, Matsubara T, Tanaka M, Shikoh E, Zhao L, Zou Y, Komatsu N, Ikado Y, Takezawa Y, Kage-Nakadai E, Izutsu Y, Yoshizato K, Morita S, Tokunaga M, Yukawa H, Baba Y, Teki Y, Fujiwara M.

    Lab on a Chip   2022.05

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1039/d2lc00112h

  • The defense response of Caenorhabditis elegans to Cutibacterium acnes SK137 via the TIR-1-p38 MAPK signaling pathway. Reviewed

    Tsuru A, Hamazaki Y, Tomida S, Ali MS, Kage-Nakadai E

    Bioscience, biotechnology, and biochemistry   2021.12( ISSN:0916-8451

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/bbb/zbab218

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  • Seroepidemiological survey on pigs and cattle for novel K88 (F4)-like colonization factor detected in human enterotoxigenic Escherichia coli Reviewed

    Yoshihiko Tanimoto, Miyoko Inoue, Kana Komatsu, Atsuyuki Odani, Takayuki Wada, Eriko Kage-Nakadai, Yoshikazu Nishikawa

    Cambridge University Press (CUP) Epidemiology and Infection   1 - 21   2021.12( ISSN:0950-2688

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1017/s0950268821002697

  • Nonpathogenic Cutibacterium acnes Confers Host Resistance against Staphylococcus aureus. Reviewed

    Tsuru A, Hamazaki Y, Tomida S, Ali MS, Komura T, Nishikawa Y, Kage-Nakadai E

    Microbiology spectrum   9 ( 2 )   e0056221   2021.10

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    Publishing type:Research paper (scientific journal)  

    Cutibacterium acnes is a human skin-resident bacterium. Although C. acnes maintains skin health by inhibiting invasion from pathogens like Staphylococcus aureus, it also contributes to several diseases, including acne. Studies suggest that differences in genetic background may explain the diverse phenotypes of C. acnes strains. In this study, we investigated the effects of C. acnes strains on the Caenorhabditis elegans life span and observed that some strains shortened the life span, whereas other strains, such as strain HL110PA4, did not alter it. Next, we assessed the effects of C. acnes HL110PA4 on host resistance against S. aureus. The survival time of C. acnes HL110PA4-fed wild-type animals was significantly longer than that of Escherichia coli OP50 control bacterium-fed worms upon infection with S. aureus. Although the survival times of worms harboring mutations at the daf-16/FoxO and skn-1/Nrf2 loci were similar to those of wild-type worms after S. aureus infection, administration of C. acnes failed to improve survival times of tir-1/SARM1, nsy-1/mitogen-activated protein kinase kinase kinase (MAPKKK), sek-1/mitogen-activated protein kinase kinase (MAPKK), and pmk-1/p38 mitogen-activated protein kinase (MAPK) mutants. These results suggest that the TIR-1 and p38 MAPK pathways are involved in conferring host resistance against S. aureus in a C. acnes-mediated manner. IMPORTANCE Cutibacterium acnes is one of the most common bacterial species residing on the human skin. Although the pathogenic properties of C. acnes, such as its association with acne vulgaris, have been widely described, its beneficial aspects have not been well characterized. Our study classifies C. acnes strains based on its pathogenic potential toward the model host C. elegans and reveals that the life span of C. elegans worms fed on C. acnes was consistent with the clinical association of C. acnes ribotypes with acne or nonacne. Furthermore, nonpathogenic C. acnes confers host resistance against the opportunistic pathogen Staphylococcus aureus. Our study provides insights into the impact of C. acnes on the host immune system and its potential roles in the ecosystem of skin microbiota.

    DOI: 10.1128/Spectrum.00562-21

    PubMed

  • Bacillus subtilis var. natto increases the resistance of Caenorhabditis elegans to gram-positive bacteria Reviewed

    Katayama R., Matsumoto Y., Higashi Y., Sun S., Sasao H., Tanimoto Y., Nishikawa Y., Kage-Nakadai E.

    JOURNAL OF APPLIED MICROBIOLOGY   2021.06( ISSN:1364-5072

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jam.15156

  • Metolazone upregulates mitochondrial chaperones and extends lifespan in Caenorhabditis elegans. Reviewed

    Ito A, Zhao Q, Tanaka Y, Yasui M, Katayama R, Sun S, Tanimoto Y, Nishikawa Y, Kage-Nakadai E

    Biogerontology   22 ( 1 )   119 - 131   2021.02( ISSN:1389-5729

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    Accumulating studies have argued that the mitochondrial unfolded protein response (UPRmt) is a mitochondrial stress response that promotes longevity in model organisms. In the present study, we screened an off-patent drug library to identify compounds that activate UPRmt using a mitochondrial chaperone hsp-6::GFP reporter system in Caenorhabditis elegans. Metolazone, a diuretic primarily used to treat congestive heart failure and high blood pressure, was identified as a prominent hit as it upregulated hsp-6::GFP and not the endoplasmic reticulum chaperone hsp-4::GFP. Furthermore, metolazone specifically induced the expression of mitochondrial chaperones in the HeLa cell line. Metolazone also extended the lifespan of worms in a atfs-1 and ubl-5-dependent manner. Notably, metolazone failed to increase lifespan in worms with knocked-down nkcc-1. These results suggested that metolazone activates the UPRmt across species and prolongs the lifespan of C. elegans.

    DOI: 10.1007/s10522-020-09907-6

    PubMed

  • Impacts of Endocrine Disruptor di-<i>n</i>-Butyl Phthalate Ester on Microalga <i>Chlorella vulgaris</i> Verified by Approaches of Proteomics and Gene Ontology. Reviewed

    Liao CS, Hong YH, Nishikawa Y, Kage-Nakadai E, Chiou TY, Wu CC

    Molecules (Basel, Switzerland)   25 ( 18 )   2020.09

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    Di-n-butyl phthalate (DBP) is an extensively used plasticizer. Most investigations on DBP have been concentrated on its environmental distribution and toxicity to humans. However, information on the effects of plasticizers on algal species is scarce. This study verified the impacts of endocrine disruptor di-n-butyl phthalate ester on microalga Chlorella vulgaris by approaches of proteomics and gene ontology. The algal acute biotoxicity results showed that the 24h-EC50 of DBP for C. vulgaris was 4.95 mg L-1, which caused a decrease in the chlorophyll a content and an increase in the DBP concentration of C. vulgaris. Proteomic analysis led to the identification of 1257 C. vulgaris proteins. Sixty-one more proteins showed increased expression, compared to proteins with decreased expression. This result illustrates that exposure to DBP generally enhances protein expression in C. vulgaris. GO annotation showed that both acetolactate synthase (ALS) and GDP-L-fucose synthase 2 (GER2) decreased more than 1.5-fold after exposure to DBP. These effects could inhibit both the valine biosynthetic process and the nucleotide-sugar metabolic process in C. vulgaris. The results of this study demonstrate that DBP could inhibit growth and cause significant changes to the biosynthesis-relevant proteins in C. vulgaris.

    DOI: 10.3390/molecules25184304

    PubMed

  • Real-time nanodiamond thermometry probing in vivo thermogenic responses. Reviewed

    Fujiwara M, Sun S, Dohms A, Nishimura Y, Suto K, Takezawa Y, Oshimi K, Zhao L, Sadzak N, Umehara Y, Teki Y, Komatsu N, Benson O, Shikano Y, Kage-Nakadai E

    Science advances   6 ( 37 )   2020.09( ISSN:2375-2548

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    Real-time temperature monitoring inside living organisms provides a direct measure of their biological activities. However, it is challenging to reduce the size of biocompatible thermometers down to submicrometers, despite their potential applications for the thermal imaging of subtissue structures with single-cell resolution. Here, using quantum nanothermometers based on optically accessible electron spins in nanodiamonds, we demonstrate in vivo real-time temperature monitoring inside Caenorhabditis elegans worms. We developed a microscope system that integrates a quick-docking sample chamber, particle tracking, and an error correction filter for temperature monitoring of mobile nanodiamonds inside live adult worms with a precision of ±0.22°C. With this system, we determined temperature increases based on the worms' thermogenic responses during the chemical stimuli of mitochondrial uncouplers. Our technique demonstrates the submicrometer localization of temperature information in living animals and direct identification of their pharmacological thermogenesis, which may allow for quantification of their biological activities based on temperature.

    DOI: 10.1126/sciadv.aba9636

    PubMed

  • Prevalence of Virulence Genes of Diarrheagenic Escherichia coli in Fecal Samples Obtained from Cattle, Poultry and Diarrheic Patients in Bangladesh. Reviewed International coauthorship

    Parvej MS, Alam MA, Shono M, Zahan MN, Masuma Parvez MM, Karim Ansari W, Jowel MS, Uddin MS, Kage-Nakadai E, Rahman MT, Nishikawa Y

    国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会 Japanese journal of infectious diseases   2019.08( ISSN:1344-6304

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    <p>Using multiplex real-time PCR, 960 fecal samples collected from poultry, cattle, and diarrheic patients in Bangladesh were screened for diarrheagenic <i>Escherichia coli</i> (DEC). Invasion-related gene <i>virB</i> had the highest prevalence in human patients (41%) and was shown to be positively correlated first with <i>afaB</i> for diffuse adhesion and second with <i>aggR</i> for aggregative adhesion. These three genes were specific to patients. In contrast, Shiga toxin genes <i>stx1</i> (57%) and <i>stx2</i> (40%) were prevalent in cattle samples. <i>eae</i> for attaching and effacing lesion, and <i>elt</i> and <i>est</i> of enterotoxins were detected from all three sample sources. Heat map and hierarchical clustering assigned the samples into five different clusters with patient samples positive for <i>virB</i> and <i>afaB</i> placing together in one cluster. Although detection of virulence genes cannot be a direct indication of the distribution of DEC organisms, their detection suggests that <i>Shigella</i> spp. or enteroinvasive <i>E. coli</i> are the most prevalent among diarrheagenic bacteria in Bangladesh and that diffusely adherent <i>E. coli</i> are concomitant bacterium. <i>eae</i>-possessing organisms in patients may come from cattle and poultry sources. The small number of <i>stx</i>-positive patients could be explained by the small number of animal samples that were positive for both <i>eae</i> and <i>stx</i>.</p>

    DOI: 10.7883/yoken.JJID.2019.016

    PubMed

    CiNii Article

  • Toll-like receptor homolog TOL-1 regulates Bifidobacterium infantis-elicited longevity and behavior in Caenorhabditis elegans(和訳中) Reviewed International coauthorship

    Sun Simo, Mizuno Yasuko, Komura Tomomi, Nishikawa Yoshikazu, Kage-Nakadai Eriko

    BMFH出版会 Bioscience of Microbiota, Food and Health   38 ( 3 )   105 - 110   2019.07( ISSN:2186-6953

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  • daf-16/FOXO isoform b in AIY neurons is involved in low preference for Bifidobacterium infantis in Caenorhabditis elegans. Reviewed

    Sun S, Ohta A, Kuhara A, Nishikawa Y, Kage-Nakadai E

    Neuroscience research   2019.02( ISSN:0168-0102

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.neures.2019.01.011

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  • Host range-associated clustering based on multi-locus variable-number tandem-repeat analysis, phylotypes, and virulence genes of atypical enteropathogenic <i>Escherichia coli</i> strains. Reviewed International coauthorship

    Parvej MS, Nakamura H, Alam MA, Wang L, Zhang S, Emura K, Kage-Nakadai E, Wada T, Hara-Kudo Y, Nishikawa Y

    Applied and environmental microbiology   2019.01( ISSN:0099-2240

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1128/AEM.02796-18

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  • Diffusely adherent Escherichia coli strains isolated from healthy carriers suppress cytokine secretions of epithelial cells stimulated by inflammatory substances. Reviewed

    Tanimoto Y, Tamai S, Matsuzaki T, Takeuchi N, Noju T, Yanagida S, Kage-Nakadai E, Yamaguchi Y, Kodama T, Nakamura S, Motooka D, Iida T, Nishikawa Y

    Infection and immunity   87 ( 1 )   2019.01( ISSN:0019-9567

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1128/IAI.00683-18

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  • Toll-like receptor homolog TOL-1 regulates <i>Bifidobacterium infantis</i>-elicited longevity and behavior in <i>Caenorhabditis elegans</i>. Reviewed

    Sun S, Mizuno Y, Komura T, Nishikawa Y, Kage-Nakadai E

    Bioscience of microbiota, food and health   38 ( 3 )   105 - 110   2019( ISSN:2186-6953

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:Domestic journal  

    Bifidobacterium infantis, a Gram-positive bacterium, is one of the commonly used probiotics. We previously showed that B. infantis modified host defense systems and extended the lifespan of the nematode Caenorhabditis elegans. In the present study, we showed that the lifespan extension caused by B. infantis was enhanced in animals having a mutation in the tol-1 gene that encodes the sole C. elegans homolog of Toll-like receptors (TLRs). Meanwhile, lifespan increased by other probiotic bacteria, such as Bacillus subtilis or Clostridium butyricum, was not affected in the tol-1 mutant animals. A microarray analysis revealed that the expression of innate immune response-related genes was significantly increased in the tol-1 mutant. Worms with the tol-1 mutation exhibited reduced leaving behavior from the B. infantis lawn, while canonical downstream factors trf-1/TRAF and ikb-1/IκB appeared to not be involved. In conclusion, C. elegans tol-1/TLR regulates B. infantis-induced longevity and also regulates behavior against B. infantis.

    DOI: 10.12938/bmfh.18-031

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  • <i>Clostridium butyricum</i> MIYAIRI 588 Increases the Lifespan and Multiple-Stress Resistance of <i>Caenorhabditis elegans</i>. Reviewed

    Kato M, Hamazaki Y, Sun S, Nishikawa Y, Kage-Nakadai E

    Nutrients   10 ( 12 )   2018.12( ISSN:2072-6643

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.3390/nu10121921

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  • The small GTPase ARF-1.2 is a regulator of unicellular tube formation in Caenorhabditis elegans. Reviewed

    Kage-Nakadai E, Sun S, Iwata S, Yoshina S, Nishikawa Y, Mitani S

    The journal of physiological sciences : JPS   2018.04( ISSN:1880-6546

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1007/s12576-018-0617-5

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  • Imbalanced Expression of Tau and Tubulin Induces Neuronal Dysfunction in <i>C. elegans</i> Models of Tauopathy. Reviewed

    Miyasaka T, Shinzaki Y, Yoshimura S, Yoshina S, Kage-Nakadai E, Mitani S, Ihara Y

    Frontiers in neuroscience   12   415   2018( ISSN:1662-4548

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.3389/fnins.2018.00415

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  • Influence of lactic acid and post-treatment recovery time on the heat resistance of Listeria monocytogenes Reviewed

    Omori Yasuo, Miake Kiyotaka, Nakamura Hiromi, Kage-Nakadai Eriko, Nishikawa Yoshikazu

    INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY   257   10 - 18   2017.09( ISSN:0168-1605

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.ijfoodmicro.2017.06.008

  • Prevalence, antimicrobial resistance and multiple-locus variable-number tandem-repeat analysis profiles of diarrheagenic Escherichia coli isolated from different retail foods Reviewed

    Wang Lili, Nakamura Hiromi, Kage-Nakadai Eriko, Hara-Kudo Yukiko, Nishikawa Yoshikazu

    INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY   249   44 - 52   2017.05( ISSN:0168-1605

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.ijfoodmicro.2017.03.003

  • Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans. Reviewed

    Nakatani Y, Yaguchi Y, Komura T, Nakadai M, Terao K, Kage-Nakadai E, Nishikawa Y

    European journal of nutrition   57 ( 3 )   1137 - 1146   2017.02( ISSN:1436-6207

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1007/s00394-017-1396-0

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  • Comparison by multilocus variable-number tandem repeat analysis and antimicrobial resistance among atypical enteropathogenic Escherichia coli strains isolated from food samples and human and animal faecal specimens Reviewed International coauthorship

    Wang L., Nakamura H., Kage-Nakadai E., Hara-Kudo Y., Nishikawa Y.

    JOURNAL OF APPLIED MICROBIOLOGY   122 ( 1 )   268 - 278   2017.01( ISSN:1364-5072

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1111/jam.13322

  • Prevalence of Diarrheagenic <i>Escherichia coli</i> in Foods and Fecal Specimens Obtained from Cattle, Pigs, Chickens, Asymptomatic Carriers, and Patients in Osaka and Hyogo, Japan Reviewed International coauthorship

    Wang Lili, Zhang Shaobo, Zheng Dongming, Fujihara Sami, Wakabayashi Akiyo, Okahata Kazuyuki, Suzuki Masakazu, Saeki Atsunori, Nakamura Hiromi, Hara-Kudo Yukiko, Kage-Nakadai Eriko, Nishikawa Yoshikazu

    国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会 Japanese Journal of Infectious Diseases   2017

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    The source and routes of diarrheagenic <i>Escherichia coli</i> (DEC) remain poorly clarified. To investigate the involvement of domestic animals in the dissemination of DEC, the prevalence of DEC among foods and fecal specimens of cattle, pigs, chickens, healthy carriers, and patients in Osaka and Hyogo, Japan, was investigated using a multiplex real-time PCR assay. The most prevalent virulence genes were <i>astA</i> and <i>eae</i>, with prevalences of 46.8% and 27.4%, respectively. <i>stx1</i> (26.6%) and <i>stx2</i> (45.9%) were prevalent in cattle feces, and <i>est</i> (8.5%) and <i>elt</i> (7.6%) were prevalent in pig feces. The <i>afaB</i> gene was the second-most prevalent gene in patients and healthy carriers, with detection rates of 5.1% and 8.1%, respectively. In contrast, <i>afaB</i> was not detected in animal feces and foods, with the exception of three porcine fecal samples. The <i>aggR</i> gene was more prevalent in humans than in foods or animal feces. Not only Shiga toxin-producing <i>E. coli</i> but atypical enteropathogenic <i>E. coli</i> carried by cattle may be a source of diarrheal diseases in humans. Pigs may be the source of human enterotoxigenic <i>E. coli</i> infections, whereas humans are expected to be the reservoir of diffusely adhering <i>E. coli</i>, enteroaggregative <i>E. coli</i>, and enteroinvasive <i>E. coli</i>.

    DOI: 10.7883/yoken.JJID.2016.486

    CiNii Article

  • Distinct roles of the two VPS33 proteins in the endolysosomal system in Caenorhabditis elegans Reviewed

    Gengyo-Ando Keiko, Kage-Nakadai Eriko, Yoshina Sawako, Otori Muneyoshi, Kagawa-Nagamura Yuko, Nakai Junichi, Mitani Shohei

    TRAFFIC   17 ( 11 )   1197 - 1213   2016.11( ISSN:1398-9219

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    DOI: 10.1111/tra.12430

  • Caenorhabditis elegans homologue of Prox1/Prospero is expressed in the glia and is required for sensory behavior and cold tolerance Reviewed

    Kage-Nakadai Eriko, Ohta Akane, Ujisawa Tomoyo, Sun Simo, Nishikawa Yoshikazu, Kuhara Atsushi, Mitani Shohei

    GENES TO CELLS   21 ( 9 )   936 - 948   2016.09( ISSN:1356-9597

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1111/gtc.12394

  • Endomembrane-associated RSD-3 is important for RNAi induced by extracellular silencing RNA in both somatic and germ cells of Caenorhabditis elegans Reviewed

    Imae Rieko, Dejima Katsufumi, Kage-Nakadai Eriko, Arai Hiroyuki, Mitani Shohei

    SCIENTIFIC REPORTS   6   2016.06( ISSN:2045-2322

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/srep28198

  • Curcumin improves tau-induced neuronal dysfunction of nematodes Reviewed

    Miyasaka Tomohiro, Xie Ce, Yoshimura Satomi, Shinzaki Yuki, Yoshina Sawako, Kage-Nakadai Eriko, Mitani Shohei, Ihara Yasuo

    NEUROBIOLOGY OF AGING   39   69 - 81   2016.03( ISSN:0197-4580

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.neurobiolaging.2015.11.004

  • Locus-specific integration of extrachromosomal transgenes in <i>C. elegans</i> with the CRISPR/Cas9 system. Reviewed

    Yoshina S, Suehiro Y, Kage-Nakadai E, Mitani S

    Biochemistry and biophysics reports   5   70 - 76   2016.03

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.bbrep.2015.11.017

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  • Characterization of unstable pEntYN10 from enterotoxigenic Escherichia coli (ETEC) O169:H41 Reviewed

    Ban Erika, Yoshida Yuka, Wakushima Mitsuko, Wajima Takeaki, Hamabata Takashi, Ichikawa Naoki, Abe Hiroyuki, Horiguchi Yasuhiko, Hara-Kudo Yukiko, Kage-Nakadai Eriko, Yamamoto Taro, Wada Takayuki, Nishikawa Yoshikazu

    VIRULENCE   6 ( 8 )   735 - 744   2015.11( ISSN:2150-5594

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1080/21505594.2015.1094606

  • The Tumor Suppressor BCL7B Functions in the Wnt Signaling Pathway. Reviewed

    Uehara T, Kage-Nakadai E, Yoshina S, Imae R, Mitani S

    PLoS genetics   11 ( 1 )   e1004921   2015.01( ISSN:1553-7390

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1371/journal.pgen.1004921

    PubMed

  • A Conditional Knockout Toolkit for Caenorhabditis elegans Based on the Cre/loxP Recombination Reviewed

    Kage-Nakadai Eriko, Imae Rieko, Suehiro Yuji, Yoshina Sawako, Hori Sayaka, Mitani Shohei

    PLOS ONE   9 ( 12 )   2014.12( ISSN:1932-6203

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1371/journal.pone.0114680

  • Influence of oral supplementation with sesamin on longevity of Caenorhabditis elegans and the host defense. Reviewed

    Yaguchi Y, Komura T, Kashima N, Tamura M, Kage-Nakadai E, Saeki S, Terao K, Nishikawa Y

    European journal of nutrition   53 ( 8 )   1659 - 1668   2014.12( ISSN:1436-6207

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1007/s00394-014-0671-6

    PubMed

  • Methods for single/low-copy integration by ultraviolet and trimethylpsoralen treatment in Caenorhabditis elegans Reviewed

    Kage-Nakadai Eriko, Imae Rieko, Yoshina Sawako, Mitani Shohei

    METHODS   68 ( 3 )   397 - 402   2014.08( ISSN:1046-2023

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.ymeth.2014.02.036

  • The homologous carboxyl-terminal domains of microtubule-associated protein 2 and TAU induce neuronal dysfunction and have differential fates in the evolution of neurofibrillary tangles. Reviewed

    Xie C, Miyasaka T, Yoshimura S, Hatsuta H, Yoshina S, Kage-Nakadai E, Mitani S, Murayama S, Ihara Y

    PloS one   9 ( 2 )   e89796   2014

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    DOI: 10.1371/journal.pone.0089796

    PubMed

  • Mitochondria-type GPAT is required for mitochondrial fusion. Reviewed

    Ohba Y, Sakuragi T, Kage-Nakadai E, Tomioka NH, Kono N, Imae R, Inoue A, Aoki J, Ishihara N, Inoue T, Mitani S, Arai H

    The EMBO journal   32 ( 9 )   1265 - 79   2013.05( ISSN:0261-4189

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/emboj.2013.77

    PubMed

  • large-scale screening for targeted knockouts in the Caenorhabditis elegans genome. Reviewed International coauthorship

    C. elegans Deletion Mutant Consortium.

    G3 (Bethesda)   2 ( 11 )   1415 - 1425   2012.11

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  • Depletion of mboa-7, an enzyme that incorporates polyunsaturated fatty acids into phosphatidylinositol (PI), impairs PI 3-phosphate signaling in Caenorhabditis elegans. Reviewed

    Lee HC, Kubo T, Kono N, Kage-Nakadai E, Gengyo-Ando K, Mitani S, Inoue T, Arai H

    Genes to cells : devoted to molecular & cellular mechanisms   17 ( 9 )   748 - 57   2012.09( ISSN:1356-9597

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1111/j.1365-2443.2012.01624.x

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  • Reduced expression of BTBD10, an Akt activator, leads to motor neuron death.

    Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, Matsuoka M.

    Cell Death Differ.   2012.08

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  • C. elegans Secreted Lipid-Binding Protein NRF-5 Mediates PS Appearance on Phagocytes for Cell Corpse Engulfment. Reviewed International coauthorship

    Zhang Y, Wang H, Kage-Nakadai E, Mitani S, Wang X

    Current biology   22 ( 14 )   1276 - 84   2012.07( ISSN:0960-9822

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.cub.2012.06.004

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  • GPI-anchor Synthesis Is Indispensable for the Germline Development of the Nematode Caenorhabditis elegans. Reviewed

    Murata D, Nomura KH, Dejima K, Mizuguchi S, Kawasaki N, Matsuishi-Nakajima Y, Ito S, Gengyo-Ando K, Kage-Nakadai E, Mitani S, Nomura K

    Molecular biology of the cell   23 ( 6 )   982 - 95   2012.03( ISSN:1059-1524

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1091/mbc.E10-10-0855

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  • Single/low-copy integration of transgenes in Caenorhabditis elegans using an ultraviolet trimethylpsoralen method.

    Kage-Nakadai E, Kobuna H, Funatsu O, Otori M, Gengyo-Ando K, Yoshina S, Hori S, Mitani S.

    BMC Biotechnol.   12 ( 1 )   2012.01

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  • NRFL-1, the C. elegans NHERF Orthologue, Interacts with Amino Acid Transporter 6 (AAT-6) for Age-Dependent Maintenance of AAT-6 on the Membrane. Reviewed

    Hagiwara K, Nagamori S, Umemura YM, Ohgaki R, Tanaka H, Murata D, Nakagomi S, Nomura KH, Kage-Nakadai E, Mitani S, Nomura K, Kanai Y

    PLoS one   7 ( 8 )   e43050   2012

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1371/journal.pone.0043050

    PubMed

  • H+/myo-inositol transporter genes, hmit-1.1 and hmit-1.2, have roles in the osmoprotective response in Caenorhabditis elegans.

    Kage-Nakadai E, Uehara T, Mitani S.

    Biochem Biophys Res Commun.   410 ( 3 )   471 - 477   2011.07

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  • Ceramide glucosyltransferase of the nematode Caenorhabditis elegans is involved in oocyte formation and in early embryonic cell division. Reviewed

    Nomura KH, Murata D, Hayashi Y, Dejima K, Mizuguchi S, Kage-Nakadai E, Gengyo-Ando K, Mitani S, Hirabayashi Y, Ito M, Nomura K

    Glycobiology   21 ( 6 )   834 - 48   2011.06( ISSN:0959-6658

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    DOI: 10.1093/glycob/cwr019

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    CiNii Article

  • Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. Reviewed

    Imae R, Inoue T, Kimura M, Kanamori T, Tomioka NH, Kage-Nakadai E, Mitani S, Arai H

    Molecular biology of the cell   21 ( 18 )   3114 - 24   2010.09( ISSN:1059-1524

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    DOI: 10.1091/mbc.E10-03-0195

    PubMed

  • Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor. Reviewed International coauthorship

    Wang X, Li W, Zhao D, Liu B, Shi Y, Chen B, Yang H, Guo P, Geng X, Shang Z, Peden E, Kage-Nakadai E, Mitani S, Xue D

    Nature cell biology   12 ( 7 )   655 - 64   2010.07( ISSN:1465-7392

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/ncb2068

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  • Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease. Reviewed International coauthorship

    Nakagawa A, Shi Y, Kage-Nakadai E, Mitani S, Xue D

    Science (New York, N.Y.)   328 ( 5976 )   327 - 34   2010.04( ISSN:0036-8075

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1126/science.1182374

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    CiNii Article

  • Magnesium excretion in C. elegans requires the activity of the GTL-2 TRPM channel. Reviewed

    Teramoto T, Sternick LA, Kage-Nakadai E, Sajjadi S, Siembida J, Mitani S, Iwasaki K, Lambie EJ

    PloS one   5 ( 3 )   e9589   2010.03

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    DOI: 10.1371/journal.pone.0009589

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  • Two very long chain fatty acid acyl-CoA synthetase genes, acs-20 and acs-22, have roles in the cuticle surface barrier in Caenorhabditis elegans. Reviewed

    Kage-Nakadai E, Kobuna H, Kimura M, Gengyo-Ando K, Inoue T, Arai H, Mitani S.

    PLoS One   5 ( 1 )   e8857   2010.01

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  • The roles and acting mechanism of Caenorhabditis elegans DNase II genes in apoptotic dna degradation and development. Reviewed International coauthorship

    Lai HJ, Lo SJ, Kage-Nakadai E, Mitani S, Xue D

    PLoS one   4 ( 10 )   e7348   2009.10

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    DOI: 10.1371/journal.pone.0007348

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  • Caenorhabditis elegans caspase homolog CSP-2 inhibits CED-3 autoactivation and apoptosis in germ cells. Reviewed International coauthorship

    Cell Death & Differentiation   16 ( 10 )   1385 - 1394   2009.10( ISSN:1350-9047

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/cdd.2009.88

    PubMed

  • A trophic role for Wnt-Ror kinase signaling during developmental pruning in Caenorhabditis elegans. Reviewed

    Hayashi Y, Hirotsu T, Iwata R, Kage-Nakadai E, Kunitomo H, Ishihara T, Iino Y, Kubo T

    Nature neuroscience   12 ( 8 )   981 - 7   2009.08( ISSN:1097-6256

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/nn.2347

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    CiNii Article

  • Insights into social insects from the genome of the honeybee Apis mellifera. Reviewed International coauthorship

    Honeybee Genome Sequencing Consortium.

    Nature   443 ( 7114 )   931 - 949   2006.10

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome. Reviewed International coauthorship

    Kunieda T, Fujiyuki T, Kucharski R, Foret S, Ament SA, Toth AL, Ohashi K, Takeuchi H, Kamikouchi A, Kage E, Morioka M, Beye M, Kubo T, Robinson GE, Maleszka R

    Insect molecular biology   15 ( 5 )   563 - 576   2006.10( ISSN:0962-1075

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1111/j.1365-2583.2006.00677.x

    PubMed

  • MBR-1, a novel helix-turn-helix transcription factor, is required for pruning excessive neurites in Caenorhabditis elegans. Reviewed

    Kage E, Hayashi Y, Takeuchi H, Hirotsu T, Kunitomo H, Inoue T, Arai H, Iino Y, Kubo T.

    Current Biology   15 ( 17 )   1554 - 1559   2005.09

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Identification of a novel gene, Mblk-1, that encodes a putative transcription factor expressed preferentially in the large-type Kenyon cells of the honeybee brain. Reviewed

    Takeuchi H, Kage E, Sawata M, Kamikouchi A, Ohashi K, Ohara M, Fujiyuki T, Kunieda T, Sekimizu K, Natori S, Kubo T.

    Insect Mol Biol.   10 ( 5 )   487 - 494   2001.10

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Books and Other Publications

  • NVセンタを用いた温度計測と生体応用

    藤原正澄、中台(鹿毛)枝里子、湯川博、馬場嘉信( Role: Contributor)

    NTS社、量子センシングハンドブック-量子科学が切り拓く新たな領域-   2021.02 

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    Responsible for pages:pp. 83-90   Book type:Scholarly book

  • 共生微生物 生物と密接に関わるミクロな生命体

    西川禎一、中臺枝里子、小村智美( Role: Joint author ,  「Part3第9章線虫の腸内細菌」(pp.94-104)を共著。C. elegansの生活環や基本的な性質を概説した後、様々な腸内細菌と線虫の相互作用のメカニズムについての研究論文や知見をわかりやすく解説した。)

    化学同人  2016.10 

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    Total pages:281   Responsible for pages:94-104  

    哺乳類から昆虫、水生生物、植物を含めた生物と微生物との共生についてまとめた書籍。

  • Brenner’s Encyclopedia of Genetics 2nd edition, Vol 2.

    Kage-Nakadai E. and Mitani S.( Role: Joint author ,  「Developmental Genetics of Caenorhabditis elegans.」pp.308-310を共著。線虫C. elegansの胚発生、形態形成に関する遺伝学的知見について概説した。)

    Academic Press  2013.02 

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    Total pages:4368   Responsible for pages:308–310  

    遺伝学について幅広い分野をカバーした英文百科事典。医学、生命科学分野の学生や関連職業従事者対象。

  • 生物機能モデルと新しいリソース・リサーチツール

    中台ー鹿毛 枝里子, 三谷昌平( Role: Joint author ,  第3節哺乳類以外のモデル動物第4項「線虫」p.589-598を共著。モデル生物としてのC. elegans の特徴や研究材料の入手方法、データベースの利用方法について解説した。)

    エル・アイ・シー出版  2011.02 

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    Total pages:671   Responsible for pages:589-598  

    比較的新しく利用されはじめたモデル動物の特徴や利用方法についての解説書。

MISC

  • 線虫モデルにおける酪酸菌MIYAIRI 588 による寿命延伸とストレス耐性の向上 Invited

    中台(鹿毛) 枝里子、加藤 舞子、濱﨑 祐美、孫 思墨、西川 禎一

    ニューサイエンス社/月刊「細胞」   2020.10

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  • 炎症応答を抑える大腸菌:プロバイオティクスの新メンバー? Invited

    西川禎一、谷本佳彦、中台(鹿毛)枝里子

    シーエムシー出版・バイオインダストリー   36 ( 7 )   67 - 78   2019.07

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    Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Kind of work:Joint Work  

  • 線虫感覚受容器のグリア−ニューロン相互作用と低温耐性 Invited

    中台(鹿毛) 枝里子、太田 茜、宇治澤 知代、孫 思墨、西川 禎一、久原 篤、三谷 昌平

    ニューサイエンス社・月刊「細胞」   50 ( 9 )   24 - 27   2018.08

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Presentations

  • 線虫 C. elegans を用いた宮入菌短期給餌 による寿命延伸効果の分子メカニズム解析 Domestic conference

    阪倉 万葉、新家 早絵、篠山 千尋、 伊東 恵梨子、西川 禎一、中台(鹿毛) 枝里子

    第77回日本栄養・食糧学会大会  2023.05 

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    Presentation type:Poster presentation  

  • 線虫Caenorhabditis elegans を用いたピ ペリンの受容機構と生理機能に及ぼす影響 の解析 Domestic conference

    千葉 喬子、石川 清琉、中台(鹿毛) 枝里子

    第77回日本栄養・食糧学会大会  2023.05 

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    Presentation type:Poster presentation  

  • Akkermansia muciniphila 給餌による線 虫Caenorhabditis elegans の寿命延伸効 果及び抗肥満効果の評価 Domestic conference

    野本 唯菜、和田 崇之、中台(鹿毛) 枝里子

    第77回日本栄養・食糧学会大会  2023.05 

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    Presentation type:Poster presentation  

  • Probiotic evaluation and infection model system using C. elegans Invited Domestic conference

    2023.03 

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    Presentation type:Symposium, workshop panel (nominated)  

  • The effect of Carnobacterium maltaromaticum isolated from pickles on healthspan in C. elegans Domestic conference

    2023.03 

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    Presentation type:Poster presentation  

  • Molecular basis of host resistance to pathogens conferred by feeding Bacillus subtilis var. natto in C. elegans as a surrogate model International conference

    Shun Yamaguchi, Rina Katayama, Yuumi Matsumoto, Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    22nd IUNS-ICN  2022.12 

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  • Plasticity in taste preference to bitterness and astringency requires DAF-16/FOXO in the AIY interneurons in Caenorhabditis elegans International coauthorship International conference

    Seiryu Ishikawa, Yuka Takezawa, Chiharu Iida, Yuko Yamada, Mohammad Shaokat Ali, Simo Sun, Eriko Kage-Nakadai

    22nd IUNS-ICN  2022.12 

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  • Construction of enterotoxinogenic Escherichia coli infection model using Caenorhabditis elegans as an alternative host International conference

    Anri Matsuda, Takashi Ishida, Takayuki Wada, Eriko Kage-Nakadai

    22nd IUNS-ICN  2022.12 

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  • Effects of Lactococcus spp. on the lifespan and motility of Caenorhabditis elegans International coauthorship International conference

    Shino Takeuchi, Mohammad Shaokat Ali, Eriko Kage-Nakadai

    22nd IUNS-ICN  2022.12 

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  • Search for marker genes in the nematode Caenorhabditis elegans to estimate pathogenicity of Cutibacterium acnes strains. Domestic conference

    2022.12 

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    Presentation type:Poster presentation  

  • Effects of Lactococcus spp. on the lifespan and motility of Caenorhabditis elegans Domestic conference

    Shino Takeuchi, Mohammad Shaokat Ali, Eriko Kage-Nakadai

    The 45th Annunal Meeting of the Molecular Biology Society of Japan  2022.12 

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  • 線虫C. elegansを代替モデル宿主に用いたマラセチア属真菌に対する生体防御メカニズムの解析 Domestic conference

    岸田千穂、靏綾乃、髙林里香、呉雪揚、孫思墨、中台(鹿毛)枝里子

    第45回日本分子生物学会年会  2022.12 

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    Presentation type:Poster presentation  

  • 宮入菌短期給餌が線虫C.elegansに与える寿命延伸効果のメカニズム解析 Domestic conference

    阪倉万葉 新家早絵 篠山千尋 伊東恵梨子 西川禎一 中台(鹿毛)枝里子

    第45回日本分子生物学会年会  2022.12 

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    Presentation type:Poster presentation  

  • Plasticity in taste preference to Epigallocatechin gallate requires DAF-16/FOXO in the AIY interneurons in Caenorhabditis elegans International coauthorship Domestic conference

    Seiryu Ishikawa, Yuka Takezawa, Chiharu Iida, Yuko Yamada, Mohammad Shaokat Ali, Simo Sun, Eriko Kage-Nakadai

    The 45th Annunal Meeting of the Molecular Biology Society of Japan  2022.12 

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    Presentation type:Poster presentation  

  • Molecular basis of host resistance to pathogens conferred by feeding Bacillus subtilis var. natto in C. elegans as a surrogate model Domestic conference

    Shun Yamaguchi, Rina Katayama, Yuumi Matsumoto, Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    The 45th Annunal Meeting of the Molecular Biology Society of Japan  2022.12 

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    Presentation type:Poster presentation  

  • 病原性及び非病原性アクネ菌における線虫の遺伝子発現の差異及び分子メカニズムの探索 Domestic conference

    古坊穂果、靏綾乃、濱﨑佑美、冨田秀太、中台(鹿毛)枝里子

    第61回 日本栄養・食糧学会 近畿支部大会  2022.10 

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    Presentation type:Oral presentation (general)  

  • 線虫C. elegansを用いた宮入菌短期給餌による寿命延伸効果のメカニズム解明 Domestic conference

    阪倉万葉、新家早絵、篠山千尋、伊東恵梨子、西川禎一、中台(鹿毛)枝里子

    第61回 日本栄養・食糧学会 近畿支部大会  2022.10 

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  • 線虫C. elegansをモデル宿主としたマラセチア属真菌に対する免疫応答経路の解析 Domestic conference

    岸田千穂、靏綾乃、髙林里香、呉雪揚、孫思墨、中台(鹿毛)枝里子

    第61回 日本栄養・食糧学会 近畿支部大会  2022.10 

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    Presentation type:Oral presentation (general)  

  • 線虫C. elegansをモデルとしたプロバイオティクス研究 Invited Domestic conference

    中台(鹿毛) 枝里子

    第76回日本栄養・食糧学会大会  2022.06 

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    Presentation type:Symposium, workshop panel (nominated)  

  • 線虫を代替モデル宿主とした腸管毒素原性大腸菌感染モデル構築と病原メカニズム解析 Domestic conference

    松田 晏理、石田 高志、和田 崇之、 中台(鹿毛) 枝里子

    第76回日本栄養・食糧学会大会  2022.06 

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    Presentation type:Oral presentation (general)  

  • 線虫C. elegansにおけるラクトコッカス属菌給餌による寿命および運動性への影響 Domestic conference

    竹内 紫乃、Ali Mohammad Shaokat、 中台(鹿毛) 枝里子

    第76回日本栄養・食糧学会大会  2022.06 

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  • 線虫C. elegansを代替モデル宿主としたマラセチア属真菌感染時の自然免疫応答のメカニズム解析 Domestic conference

    岸田 千穂、鶴 綾乃、高林 里香、呉 雪揚、 孫 思墨、中台(鹿毛) 枝里子

    第76回日本栄養・食糧学会大会  2022.06 

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    Presentation type:Oral presentation (general)  

  • Whole-genome analysis of diffusely adherent Escherichia coli without typical adhesins Domestic conference

    2022.03 

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    Presentation type:Oral presentation (general)  

  • 渋味物質に対する嗜好性の変化に関する線虫C. elegans を用いたメカニズム解析 Domestic conference

    石川清琉、竹澤有華、飯田千晴、山田優子、孫思墨、 西川禎一、中台(鹿毛)枝里子

    日本農芸化学会関西支部例会(第519回講演会)  2022.02 

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  • 線虫C. elegans を代替モデルとした納豆菌給餌によるグラム陽性菌 への宿主抵抗性付与の分子メカニズム解析 Domestic conference

    山口 駿, 片山莉那,松本優美,孫思墨,西川禎一, 中台(鹿毛)枝里子

    日本農芸化学会関西支部例会(第519回講演会)  2022.02 

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  • 線虫C. elegansにおける宮入菌短期給餌による寿命延伸効果のメカニズ ム解析 Domestic conference

    新家 早絵, 篠山 千尋, 伊東 恵梨子, 西川 禎一, 中台(鹿毛) 枝里子

    第44回日本分子生物学会年会  2021.12 

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  • Host resistance to S. aureus conferred by C. acnes in C. elegans Domestic conference

    Ayano Tsuru, Yumi Hamazaki, Shuta Tomida, Mohammad Shaokat Ali, Tomomi Komura, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    第44回日本分子生物学会年会  2021.12 

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  • 線虫C. elegans を代替モデルとした納豆菌給餌によるグラム陽性菌 への宿主抵抗性付与の分子メカニズム解析 Domestic conference

    山口 駿, 片山莉那,松本優美,孫思墨,西川禎一, 中台(鹿毛)枝里子

    第60回 日本栄養・食糧学会 近畿支部大会  2021.11 

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  • にきびのない肌で検出されることが多いタイプのアクネ菌株による黄 色ブドウ球菌への宿主抵抗性付与のメカニズム解析 Domestic conference

    靏綾乃、濱﨑祐美、冨田秀太、小村智美、Mohammad Shaokat Ali、西川禎一、中台(鹿毛)枝里子

    第60回 日本栄養・食糧学会 近畿支部大会  2021.11 

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  • 線虫C. elegans を用いた渋味物質に対する嗜好性の変化に関するメカニズム解析 Domestic conference

    石川清琉、竹澤有華、飯田千晴、山田優子、孫思墨、 西川禎一、中台(鹿毛)枝里子

    第60回 日本栄養・食糧学会 近畿支部大会  2021.11 

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  • 線虫C. elegansにおける非病原性アクネ菌による 黄色ブドウ球菌への宿主抵抗性付与 Domestic conference

    靏綾乃、濱﨑祐美、冨田秀太、小村智美、Mohammad Shaokat Ali、西川禎一、中台(鹿毛)枝里子

    第74回日本細菌学会関西支部総会  2021.11 

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  • 定型接着因子不明な分散接着性大腸菌の全ゲノム解析 Domestic conference

    山﨑康祐、谷本佳彦、陳 彥霖、西川禎一、中台(鹿毛)枝里子、和田崇之

    第42回日本食品微生物学会学術総会  2021.09 

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  • 線虫 C. elegans を用いた渋味物質に対す る嗜好性と嗜好変化のメカニズム解析 Domestic conference

    石川 清琉、竹澤 有華、飯田 千晴、山田 優子、 孫 思墨、西川 禎一、中台(鹿毛) 枝里子

    第75回日本栄養・食糧学会大会  2021.07 

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  • Conferring host resistance to Staphylococcus aureus by Cutibacterium acnes International conference

    Ayano Tsuru, Yumi Hamazaki, Shuta Tomida, Tomomi Komura, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    World Microbe Forum 2021  2021.06 

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  • Molecular mechanisms underlying resistance to Gram-positive bacteria conferred by Bacillus subtilis var. natto in the Caenorhabditis elegans alternative model host Domestic conference

    Rina Katayama, Yumi Matsumoto, Yukina Higashi, Honoka Sasao, Yoshihiko Tanimoto, Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    第94回日本細菌学会総会  2021.03 

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  • Molecular mechanisms underlying resistance to Gram-positive bacteria conferred by Bacillus subtilis var. natto in the Caenorhabditis elegans alternative model host Domestic conference

    Rina Katayama, Yumi Matsumoto, Yukina Higashi, Honoka Sasao, Yoshihiko Tanimoto, Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    第43回日本分子生物学会年会  2020.12 

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  • Functional analysis of Hcp gene that constitutes type VI secretion systems and comprehensive screening of inflammatory suppression genes of diffusely adherent Escherichia coli isolated from healthy carrier. Domestic conference

    Atsuyuki Odani, Yoshihiko Tanimoto, Ayana Takaura, Tomomi Komura, Eriko Kage-Nakadai, Yoshikazu Nishikawa

    第43回 日本分子生物学会年会  2020.12 

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  • Host resistance to S. aureus conferred by C. acnes Domestic conference

    Ayano Tsuru, Yumi Hamazaki, Shuta Tomida, Tomomi Komura, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    第43回 日本分子生物学会年会  2020.12 

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  • 線虫C. elegansを代替モデル宿主とした納豆菌給餌によるグラム陽性菌耐性付与の分子メカニズムの解明 Domestic conference

    片山 莉那,松本 優美,東 幸菜,笹尾穂乃佳,谷本佳彦,孫思墨,西川禎,中台(鹿毛)枝里子

    第59回 日本栄養·食糧学会 近畿支部大会  2020.11 

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  • 線虫C. elegansにおける非病原性アクネ菌による 黄色ブドウ球菌への宿主抵抗性付与に関する研究 Domestic conference

    靏綾乃、濱崎祐美、冨田秀太、小村智美、西川禎一、 中台(鹿毛)枝里子

    第73回日本細菌学会関西支部総会  2020.11 

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  • 健康者由来分散接着性大腸菌株のVI型分泌装置を構成するHcp遺伝子の機能解析と炎症抑制遺伝子の網羅的探索 Domestic conference

    小谷篤幸、谷本佳彦、髙浦彩那、小村智美、和田崇之、中台(鹿毛)枝里子、西川禎一

    第73回日本細菌学会関西支部総会  2020.11 

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  • 線虫の寿命に及ぼす納豆菌給餌の影響とその分子メカニズムの探索 Domestic conference

    寺本 奈央、佐藤 可奈恵、西川 禎一、中台(鹿毛) 枝里子

    第59回 日本栄養·食糧学会 近畿支部大会  2020.11 

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  • 健康者由来分散接着性大腸菌SK1144株はDSS腸炎誘導マウスの腸炎を改善する Domestic conference

    新家早絵、高浦彩那、谷本佳彦、小谷篤幸、高山夏行、神谷知憲、大谷直子、中台(鹿毛)枝里子、西川禎一

    第74回日本栄養・食糧学会大会  2020.05 

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  • 線虫C. elegansにおけるアクネ菌による 黄色ブドウ球菌に対する抵抗性付与に関する研究 Domestic conference

    靏綾乃、濱崎祐美、冨田秀太、小村智美、西川禎一、中台(鹿毛)枝里子

    第74回日本栄養・食糧学会大会  2020.05 

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  • 線虫の寿命に及ぼす納豆菌給餌の影響 Domestic conference

    寺本 奈央、佐藤 可奈恵、西川 禎一、中台(鹿毛) 枝里子

    第74回日本栄養・食糧学会大会  2020.05 

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  • 納豆菌給餌により黄色ブドウ球菌に対する抵抗性が線虫に付与される分子メカニズム Domestic conference

    松本 優美,片山 莉那,東 幸菜,孫 思墨,西川 禎一,中台 枝里子

    第93回日本細菌学会総会(於ウインク愛知)  2020.02 

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  • Seroepidemiology on novel colonization factor of enterotoxigenic E. coli O169 in pigs and cattle. Domestic conference

    井上 三代子,鄭 冬明,大森 裕子,小松 加奈,山口 良 弘,宮田 真人,和田 崇之,麻生 久,中台(鹿毛) 枝里子, 西川 禎一

    第93回日本細菌学会総会(於ウインク愛知)  2020.02 

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  • Genes implicated in the suppression of IL-8 secretion by diffusely adherent Escherichia coli. Domestic conference

    2) 高浦 彩那,谷本 佳彦,小谷 篤幸,新家 早絵,神谷 知憲,大谷 直子,山口 良弘,小村 智美,中台(鹿毛) 枝里子,西川 禎

    第93回日本細菌学会総会(於ウインク愛知)  2020.02 

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  • 線虫C. elegansを用いた食品由来の苦味・渋味物質に対する嗜好性と嗜好変化のメカニズム解析 Domestic conference

    竹澤有華、飯田千晴、山田優子、孫思墨、西川禎一、中台(鹿毛)枝里子

    日本食品免疫学会 15周年記念学術大会(JAFI2019)(於タワーホール船堀)  2019.11 

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  • 線虫における納豆菌によるグラム陽性菌への抵抗性付与の分子メカニズム Domestic conference

    片山 莉那、松本 優美、東 幸奈、孫 思墨、西川 禎一、中台(鹿毛) 枝里子

    日本食品免疫学会 15周年記念学術大会(JAFI2019)(於タワーホール船堀)  2019.11 

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  • 線虫C. elegansを用いた食品由来の苦味・渋味物質に対する嗜好性と嗜好変化のメカニズム解析 Domestic conference

    竹澤有華,飯田千晴,山田優子,孫思墨,西川禎一,中台(鹿毛)枝里子

    第58回日本栄養・食糧学会近畿支部大会(於京都大学)  2019.11 

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  • トランスポゾン挿入により上皮細胞に対する炎症性サイトカイン分泌抑制機能を喪失した分散接着性大腸菌 Domestic conference

    髙浦彩那、谷本佳彦、小谷篤幸、新家早絵、髙山夏行、山口良弘、小村智美、中台(鹿毛)枝里子、西川禎一

    第72回日本細菌学会関西支部会(於大阪大学)  2019.11 

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  • ヒト腸管毒素原性大腸菌O169:H41の新規定着因子に対する抗体のブタおよびウシにおける保有状況 Domestic conference

    井上三代子、小松加奈、鄭 冬明、大森裕子、山口良弘、宮田真人、和田崇之、中台(鹿毛)枝里子、西川禎一

    第72回日本細菌学会関西支部会(於大阪大学)  2019.11 

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  • 線虫を代替モデル宿主とした納豆菌によるグラム陽性菌への抵抗性付与のメカニズム解析 Domestic conference

    片山 莉那、松本 優美、東 幸奈、孫 思墨、西川 禎一、中台(鹿毛) 枝里子

    第58回日本栄養・食糧学会近畿支部大会(於京都大学)  2019.11 

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  • In vivo imaging of the nervous system of the nematode C. elegans Invited International conference

    Eriko Kage-Nakadai

    International Workshop on Quantum Sensing & Biophotonics 2019(Osaka City Univ.)  2019.09 

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  • Molecular mechanism underlying resistance to Gram-positive bacteria conferred by Bacillus subtilis var. natto in C. elegans International conference

    Rina Katayama, Yumi Matsumoto, Yukina Higashi, Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    International Workshop on Quantum Sensing & Biophotonics 2019  2019.09 

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  • Elucidation of the mechanisms underlying preference to bitter and astringent compounds in foods using C. elegans International conference

    Yuka Takezawa, Chiharu Iida, Yuko Yamada, Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    International Workshop on Quantum Sensing & Biophotonics 2019  2019.09 

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  • A search for genes suppressing inflammatory response of epithelial cells in diffusely adherent Escherichia coli: trial by transposon insertion mutants International conference

    Ayana Takaura, Narumi Takeuchi, Yoshihiko Tanimoto, Eriko Kage-Nakadai, Yoshikazu Nishikawa

    International Workshop on Quantum Sensing & Biophotonics 2019  2019.09 

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  • Effect of diffusely adherent Escherichia coli (DAEC) strain SK1144 isolated from healthy carrier on DSS-induced colitis of mice International conference

    Atsuyuki Odani, Ayana Takaura, Sae Shinya, Natsuyuki Takayama, Yoshihiko Tanimoto, Eriko Kage-Nakadai, Yoshikazu Nishikawa

    International Workshop on Quantum Sensing & Biophotonics 2019  2019.09 

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  • 線虫における納豆菌によるグラム陽性菌への抵抗性付与の分子メカニズム Domestic conference

    片山 莉那、松本 優美、東 幸奈、孫 思墨、西川 禎一、中台(鹿毛) 枝里子

    第73回日本栄養・食糧学会大会(於静岡県立大学)  2019.05 

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  • 線虫における納豆菌による黄色ブドウ球菌への抵抗性付与の分子機構 Domestic conference

    松本 優美、片山 莉那、東 幸奈、孫 思墨、西川 禎一、 中台(鹿毛) 枝里子

    第57回日本栄養・食糧学会 近畿支部大会(於畿央大学)  2018.12 

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  • 食品中の苦味物質に対する嗜好の変化のメカニズム解析 Domestic conference

    飯田千晴, 孫思墨, 西川禎一, 中台(鹿毛)枝里子

    第57回日本栄養・食糧学会 近畿支部大会(於畿央大学)  2018.12 

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  • Neural and molecular basis involved in low preference to Bifidobacterium infantis in Caenorhabditis elegans Domestic conference

    Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    第41回日本神経科学大会(於神戸国際会議場・展示場)  2018.07 

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  • Neural and molecular basis involved in low preference to Bifidobacterium infantis in Caenorhabditis elegans International conference

    Simo Sun, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    The 2018 C. elegans “Topics” Meeting, covering Aging, Metabolism, Pathogenesis, Stress, and Small RNAs (Madison, Wisconsin, USA)  2018.07 

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  • 納豆菌による黄色ブドウ球菌に対する抵抗性付与の分子メカニズム Domestic conference

    松本 優美、東 幸奈、稲田 智史、上村 了美、西川 禎一、 中台(鹿毛) 枝里子

    第72回日本栄養・食糧学会大会(岡山県立大学)  2018.05 

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  • 健康者由来の分散接着性大腸菌はVI型分泌装置によって上皮細胞からのIL-8分泌を抑制する Domestic conference

    谷本 佳彦,竹内 成美,玉井 沙也加,柳田 咲,中台 枝里子,山口 良弘,西川 禎一

    第70回日本細菌学会関西支部総会(於I-site なんば)  2017.11 

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  • ウェルシュ菌培養上清が線虫(Caenorhabditis elegans)に及ぼす影響 Domestic conference

    藤木侑里香、安木真世、中台(鹿毛)枝里子、西川禎一、三宅眞実

    第70回日本細菌学会関西支部総会(於I-site なんば)  2017.11 

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  • 線虫におけるビフィズス菌(Bifidobacterium infantis)への低嗜好性に関わるニューロンおよび分子メカニズム Domestic conference

    孫 思墨、西川 禎一、中台 枝里子

    第56回日本栄養・食糧学会近畿支部大会(於龍谷大学)  2017.11 

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  • 線虫 C.elegans を用いた食品中の苦味物質に対する生体応答の解析 Domestic conference

    飯田千晴、孫思墨、西川禎一、中台(鹿毛)枝里子

    第56回日本栄養・食糧学会近畿支部大会(於龍谷大学)  2017.11 

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  • ミトコンドリアUPR の活性化を介して抗老化作用をもたらす化合物の線虫モデルによる探索 Domestic conference

    伊藤愛、趙秋池、西川禎一、中台(鹿毛)枝里子

    第56回日本栄養・食糧学会近畿支部大会(於龍谷大学)  2017.11 

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  • 線⾍C.elegansを用いた食品由来の苦味物質に対する嗜好変化のメカニズム解析 Domestic conference

    飯田千晴、孫思墨、西川禎一、中台(鹿毛)枝里子

    第13回日本食品免疫学会学術大会(於東京大学)  2017.11 

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  • Adhesion of human enterotoxigenic Escherichia coli (ETEC) O169:H41 to porcine intestinal epithelial cells by the novel colonization factor. International conference

    Omori, Y., Zheng, D., Ban, E., Kage-Nakadai, E., Tachibana, T., Wada, T., Hara-Kudo, Y., and Nishikawa, Y.

    Vaccines for Enteric Diseases (Albufeira, Portugal)  2017.10 

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  • 上皮細胞からのサイトカイン分泌に対する分散接着性大腸菌の抑制効果に関与する因子の探索 Domestic conference

    谷本 佳彦, 竹内 成美, 玉井 沙也加 , 柳田 咲,中台 枝里子, 西川禎一

    第38回日本食品微生物学会学術総会(於徳島県郷土文化会館)  2017.10 

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  • Listeria monocytogenesの乳酸処理と処理後の回復時間が耐熱性に及ぼす影響 Domestic conference

    大森康雄,三明清隆,中村寛海,中台(鹿毛)枝里子,西川禎一

    第38回日本食品微生物学会学術総会(於徳島県郷土文化会館)   2017.10 

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  • Influence of Propionibacterium acnes on host defense of Caenorhabditis elegans International conference

    Yumi Hamazaki, Satomi Kamimura, Satoshi Inada, Simo Sun, Tomomi Komura, Shuta Tomida, Yoshikazu Nishikawa, Eriko Kage-Nakadai

    The 16th Awaji International Forum on Infection and Immunity(於淡路夢舞台国際会議場)  2017.09 

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  • Diffusely adherent Escherichia coli (DAEC) strains isolated from healthy carriers inhibit IL-8 secretion of epithelial cells by the type VI secretion system (T6SS) International conference

    Narumi Takeuchi, Yoshihiko Tanimoto, Sayaka Tamai, Saki Yanagida, Yoshihiro Yamaguchi, Eriko Kage-Nakadai, Yoshikazu Nishikawa

    The 16th Awaji International Forum on Infection and Immunity(於淡路夢舞台国際会議場)  2017.09 

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    Presentation type:Oral presentation (invited, special)  

  • 線虫C. elegansモデルを用いたミトコンドリアUPR活性化を介して寿命延伸効果をもたらす化合物の探索 Domestic conference

    趙秋池、伊藤愛、西川禎一、中台(鹿毛)枝里子

    第71回日本栄養・食糧学会大会(於沖縄コンベンションセンター)  2017.05 

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  • 線虫C.elegansを用いた食品に含まれる苦味物質に対する応答のメカニズム解明 Domestic conference

    飯田千晴、西川禎一、中台(鹿毛)枝里子

    第71回日本栄養・食糧学会大会(於沖縄コンベンションセンター)  2017.05 

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  • 線虫Caenorhabditis elegansの寿命と各種ストレス耐性に及ぼす宮入菌給餌の影響 Domestic conference

    加藤舞子、濱崎祐美、中台(鹿毛)枝里子、西川禎一

    第71回日本栄養・食糧学会大会(於沖縄コンベンションセンター)  2017.05 

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    Presentation type:Poster presentation  

  • ビフィズス菌の線虫C. elegansに対する抗老化効果と線虫のビフィズス菌に対する行動 Domestic conference

    孫思墨、水野靖子、小村智美、中臺枝里子、西川禎一

    第70回日本栄養・食糧学会大会(於武庫川女子大学)  2016.05 

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    Presentation type:Oral presentation (general)  

  • 黄色ブドウ球菌給餌による線虫Caenorhabditis elegansの遺伝子発現量の変化および行動 Domestic conference

    東幸奈、孫思墨、上村了美、稲田智史、西川禎一、中臺枝里子

    第70回日本栄養・食糧学会大会(於武庫川女子大学)  2016.05 

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    Presentation type:Oral presentation (general)  

  • Host responses to probiotic bacteria in C. elegans. Invited Domestic conference

    Kage-Nakadai, E., Nishikawa, Y.

    第89回日本細菌学会学術総会(於大阪国際交流センター)  2016.03 

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    Presentation type:Symposium, workshop panel (nominated)  

  • A Caenorhabditis elegans homolog of Prox1/Prospero functions in the glia and is required for the development of sensory neurons. Domestic conference

    Kage-Nakadai, E., Sun, S., Nishikawa, Y., Mitani, S.

    第38回日本神経科学大会(於パシフィコ横浜)  2015.07 

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    Presentation type:Oral presentation (general)  

  • Diffusely adherent Escherichia coli (DAEC) strains isolated from healthy carriers inhibit IL-8 secretion of HEK293 cells stimulated by inflammatory substances. International conference

    Noju, T., Matsuzaki, T., Tamai, S., Tanimoto, Y., Kage-Nakadai, E., and Nishikawa, Y.

    E. coli and the Mucosal Immune System (Ghent, Belgium)  2015.07 

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    Presentation type:Oral presentation (general)  

  • Complete DNA sequence of the virulence plasmid of enterotoxigenic Escherichia coli O169:H41 and characterization of a novel adherence factor. International conference

    Ban, E., Yoshida, Y., Ikezaki, S., Zheng, D., Kage-Nakadai, E., Wada, T., Wajima, T., Hamabata, T., Horiguchi, Y., Ichikawa, N., Hara-Kudo, Y., and Nishikawa, Y.

    E. coli and the Mucosal Immune System (Ghent, Belgium)  2015.07 

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    Presentation type:Oral presentation (general)  

  • HEp-2細胞に対して特異な凝集接着を示す腸管毒素原性大腸菌O169:H41の接着因子 Domestic conference

    坂 瑛里香、吉田優香、和田崇之、輪島丈明、濱端 崇、市川直樹、堀口安彦、中臺枝里子、西川禎一

    第67回日本細菌学会関西支部総会(於兵庫医科大学)  2014.11 

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    Presentation type:Oral presentation (general)  

  • 培養上皮細胞 におけるべん毛によるIL-8産生誘 導に対する健康者由来分散接着性大腸菌の抑制効果 Domestic conference

    松崎壮宏、能重 匠、玉井沙也加、中臺枝里子、西川禎一

    第67回日本細菌学会関西支部総会(於兵庫医科大学)  2014.11 

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    Presentation type:Oral presentation (general)  

  • 宮入菌給餌が線虫(Caenorhabditis elegans) の寿命と各種ストレス耐性に及ぼす影響 Domestic conference

    加藤舞子、小村智美、中臺枝里子、西川禎一

    第53回日本栄養食糧学会近畿支部大会(於京都府立大学)  2014.10 

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    Presentation type:Oral presentation (general)  

  • A conditional knockout system based on the combination of UV/TMP single-copy integration methods and deletion mutant strains in C. elegans. International conference

    Kage-Nakadai, E., Imae,R., Funatsu, O., Hori, S., Suehiro, Y., Yoshina, S., Mitani, S.

    6th Asia-Pacific C. elegans Meeting(於奈良県新公会堂)  2014.06 

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Grant-in-Aid for Scientific Research

  • ミトコンドリア品質の時空間的制御と可視化による抗老化メカニズムの解明

    Grant-in-Aid for Challenging Research (Pioneering)/(Exploratory)  2022

  • 分散接着性大腸菌による腸炎抑制メカニズム解明とプロバイオティクスへの応用

    Grant-in-Aid for Scientific Research(B)  2022

  • 生体内一細胞温度計測による定量熱生物学の開拓

    Grant-in-Aid for Scientific Research(A)  2022

  • 分散接着性大腸菌による腸炎抑制メカニズム解明とプロバイオティクスへの応用

    Grant-in-Aid for Scientific Research(B)  2021.04

  • 生体内一細胞温度計測による定量熱生物学の開拓

    Grant-in-Aid for Scientific Research(A)  2020.04

  • ミトコンドリアストレス応答を介して寿命を延伸する化合物の同定と作用機序解明

    Grant-in-Aid for Scientific Research(C)  2018.04

  • 世界的流行を示す腸管毒素原性大腸菌O169の新規接着因子による人獣共通感染の検証

    Grant-in-Aid for Scientific Research(B)  2017.04

  • 感覚受容器におけるグリアーニューロン相互作用の分子メカニズムに関する研究

    Grant-in-Aid for Young Scientists(B)  2014.04

  • グリア細胞を介した浸透圧制御の分子的基盤の解明

    Grant-in-Aid for Young Scientists(B)  2011.04

  • siRNAの細胞内輸送の分子メカニズムに関する研究

    Grant-in-Aid for Research Activity Start-up  2007.04

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Contract research

  • 宿主の腸炎を抑制する分散接着性大腸菌の分泌物を利用した薬剤開発への可能性検証

    日本医療研究開発機構  橋渡し研究プログラム 異分野融合型研究開発推進支援事業  2022

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