Updated on 2024/02/27

写真a

 
YAMAUCHI Makoto
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Lecturer
School of Medicine Department of Medical Science
Title
Lecturer
Affiliation
Institute of Medicine

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Lecturer  2022.04 - Now

  • School of Medicine Department of Medical Science 

    Lecturer  2022.04 - Now

Papers

  • Intestinal‑type mucinous carcinoma of the endometrium showing a polypoidal exophytic form: A case report.

    Nakano C, Fukuda T, Tanaka S, Noda T, Uchikura E, Awazu Y, Tasaka R, Imai K, Yamauchi M, Ichimura T, Yasui T, Sumi T

    Oncology letters   26 ( 4 )   444   2023.10（ ISSN:1792-1074 ）

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  • CLPTM1L expression predicts recurrence of patients with intermediate‑ and high‑risk stage IB‑IIB cervical cancer undergoing radical hysterectomy followed by TP as adjuvant chemotherapy.

    Awazu Y, Fukuda T, Noda T, Uchikura E, Nanno S, Imai K, Yamauchi M, Yasui T, Sumi T

    Oncology letters   26 ( 2 )   353   2023.08（ ISSN:1792-1074 ）

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  • Real-world Efficacy and Safety of Bevacizumab for Advanced or Recurrent Müllerian Cancer: A Single-institutional Experience.

    Fukuda T, Noda T, Uchikura E, Awazu Y, Tasaka R, Imai K, Yamauchi M, Ichimura T, Yasui T, Sumi T

    Anticancer research   43 ( 7 )   3097 - 3105   2023.07（ ISSN:0250-7005 ）

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  • Carcinomatous meningitis from ovarian serous carcinoma: A case report.

    Uchikura E, Fukuda T, Imai K, Yamauchi M, Kasai M, Ichimura T, Yasui T, Kuwae Y, Sumi T

    Oncology letters   25 ( 2 )   66   2023.02（ ISSN:1792-1074 ）

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  • 当科における進行卵巣癌に対するベバシズマブによる維持療法の有効性と安全性

    中島 安紗海, 福田 武史, 柴田 悟, 粟津 祐一朗, 南野 成則, 末包 智紀, 今井 健至, 山内 真, 笠井 真理, 市村 友季, 安井 智代, 角 俊幸

    産婦人科の進歩   74 ( 4 )   509 - 514   2022.10（ ISSN:0370-8446 ）

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    2014年4月1日から2020年12月31日までにベバシズマブを投与した卵巣癌、腹膜癌、卵管癌患者計71例(Bev投与群)とベバシズマブを使用していない時期(2008年1月1日から2014年3月31日まで)に治療した76例(Bev非投与群)を対象に、治療効果、予後および有害事象をBev投与群(TC+Bev群)とBev非投与群(TC群)で比較した。対象はTC+Bev群71例、TC群76例で、患者背景に有意差はなかった。最良効果判定では、奏効率および病勢制御率でTC+Bev群で有意に良好であった。無病再発期間では、全観察期間において有意差はなかったが、Bevによる維持療法中は、TC+Bev群で有意に良好であった。全生存期間については、全観察期間および維持療法期間で有意差はなかった。Grade3以上の有害事象の発症率は両群間で有意差はなかった。TC+Bev群におけるベバシズマブに特徴的な有害事象は、尿蛋白5例、高血圧8例、消化管穿孔3例などを認めた。これらの有害事象でベバシズマブ投与を中止した患者は71例中9例であった。

  • Fyn expression is associated with the response of patients with locally advanced uterine cervical squamous cell carcinoma to neoadjuvant chemotherapy.

    Nanno S, Fukuda T, Noda T, Uchikura E, Awazu Y, Imai K, Yamauchi M, Yasui T, Sumi T

    Molecular and clinical oncology   17 ( 4 )   147   2022.10（ ISSN:2049-9450 ）

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  • A difficult to diagnose case of low-grade endometrial stromal sarcoma with smooth muscle differentiation treated with laparoscopic surgery: A case report.

    Ichimura T, Kasai M, Imai K, Yamauchi M, Fukuda T, Yasui T, Sumi T

    Molecular and clinical oncology   16 ( 4 )   92   2022.04（ ISSN:2049-9450 ）

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  • Surface modification of the cubic micro-cartilage by collagenase treatment and its efficacy in cartilage regeneration for ear tissue engineering.

    Sueyoshi Y, Niwa A, Itani Y, Yamauchi M, Asamura S, Teramura T, Isogai N

    International journal of pediatric otorhinolaryngology   153   111037   2022.02（ ISSN:0165-5876 ）

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  • GnRHアンタゴニストは血栓症のリスクが高い子宮筋腫症例に対して有用か?　症例報告と文献的考察

    中井 建策, 田中 和東, 林 雅美, 今井 健至, 山内 真, 中川 佳代子, 羽室 明洋, 西尾 順子

    産婦人科の進歩   74 ( 1 )   27 - 31   2022.02（ ISSN:0370-8446 ）

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    子宮筋腫の治療薬としてGnRHアゴニストが広く使用されているが,添付文書上,脳血管/心血管イベントや静脈血栓症の発症リスクがあると記載されている.今回われわれが経験した症例は,両側内頸動脈狭窄症を有し重症貧血を伴う粘膜下筋腫の症例であり,GnRHアゴニストではなくGnRHアンタゴニスト製剤を選択した.症例は47歳,2妊2産(経腟分娩2回).過多月経,貧血症状を主訴に当院を受診した.初診時に経腟超音波断層法にて粘膜下筋腫と考えられる最大長径90mmの腫瘤を認めた.骨盤MRI検査で子宮体部に最大長径86mmの腫瘤を認め,粘膜下筋腫と診断した.血液検査でHb5.4g/dlと高度貧血を認め手術療法を施行する方針となった.また頭部MRA検査では両側内頸動脈の高度な狭窄を認め,当院脳神経外科共観のうえ,エストロゲン・プロゲステロン配合薬は使用せず,鉄剤注射のみで治療を行ったが,貧血は改善しなかった.その後経口GnRHアンタゴニスト(Relugolix)40mg/dayを開始し,投与後性器出血は止まり,Hb12.3g/dlと貧血は改善した.また術直前のMRI検査にて腫瘍腫瘤径は最大長径60mm程度へ縮小を認めた.手術術式については,腹腔鏡下手術の頭低位による脳循環への悪影響もあることから,開腹手術の方が安全であることを説明した.しかし本人の腹腔鏡下手術の強い希望があったため,腹腔鏡下子宮全摘出術を施行し,術後5日目に軽快退院となった.前立腺がん患者において,GnRHアゴニストは血栓塞栓症のリスクを増加させることが知られているが,婦人科良性疾患に対するGnRHアゴニスト使用に伴う血栓塞栓症はこれまで5例のみ報告されている.添付文書の記載を考慮すると,本症例のように脳梗塞のリスクが高い症例ではGnRHアゴニストではなくGnRHアンタゴニストが有力な選択肢と考えられるが,婦人科良性疾患に対して真にGnRHアンタゴニストの方が血栓塞栓症のリスクが低いのかについては,今後,多数例におけるエビデンスが必要である.(著者抄録)

  • Sleep Apnea Syndrome (SAS) Clinical Practice Guidelines 2020

    Akashiba T.

    Respiratory Investigation   60 ( 1 )   3 - 32   2022.01（ ISSN:22125345 ）

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  • Sleep Apnea Syndrome (SAS) Clinical Practice Guidelines 2020

    Akashiba T.

    Sleep and Biological Rhythms   20 ( 1 )   5 - 37   2022.01（ ISSN:14469235 ）

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  • Outcomes of long-term nivolumab and subsequent chemotherapy in Japanese patients with head and neck cancer: 2-year follow-up from a multicenter real-world study

    Yasumatsu R.

    International Journal of Clinical Oncology   27 ( 1 )   95 - 104   2022.01（ ISSN:13419625 ）

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  • Load transferring mechanism of long riveted joint partially replaced by high-strength bolts

    Chen Y.

    IABSE Symposium Prague, 2022: Challenges for Existing and Oncoming Structures - Report   173 - 180   2022（ ISBN:9783857481833 ）

  • Is GnRH antagonist useful in patients with uterine fibroids at high risk of thrombosis?

    NAKAI Kensaku, TANAKA Kazuharu, HAYASHI Masami, IMAI Kenshi, YAMAUCHI Makoto, NAKAGAWA Kayoko, HAMURO Akihiro, NISHIO Junko

    ADVANCES IN OBSTETRICS AND GYNECOLOGY   74 ( 1 )   27 - 31   2022（ ISSN:03708446 ）

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    <p>Although GnRH agonists are widely used for the treatment of uterine fibroids, the risk of cerebrovascular/cardiovascular events and venous thrombosis is described in the package insert. In the present case, a patient with bilateral internal carotid artery stenosis and submucosal myoma with severe anemia was treated with a GnRH antagonist rather than a GnRH agonist. The patient was 47 years old, had two pregnancies and two deliveries (two vaginal deliveries). She came to our clinic with complaints of excessive menstruation and anemia. On initial examination, transvaginal ultrasonography showed a mass of 90 mm in diameter that was thought to be a submucosal myoma. Pelvic MRI revealed a mass of 86 mm in diameter in the uterine corpus, which was diagnosed as submucosal myoma. Blood tests showed severe anemia with Hb 5.4 g/dl, and the patient was decided to undergo surgical treatment. In addition, head MRA showed severe stenosis of bilateral internal carotid arteries, and the patient was treated only with iron injection without estrogen-progesterone combination, but the anemia did not improve. Thereafter, an oral GnRH antagonist (Relugolix) 40 mg/day was started, and after administration, genital bleeding stopped and anemia improved to Hb12.3 g/dl. The diameter of the tumor mass was reduced to about 60 mm in length by MRI immediately before surgery. As for the surgical technique, we explained that laparotomy was safer than laparoscopy because of the adverse effect on cerebral circulation caused by the low head position of laparoscopy. However, the patient strongly desired laparoscopic surgery, so we performed a laparoscopic total hysterectomy, and the patient was discharged on the fifth postoperative day. Although GnRH agonists are known to increase the risk of thromboembolism in patients with prostate cancer, only five cases of thromboembolism associated with the use of GnRH agonists for benign gynecological diseases have been reported so far. Considering the description in the package insert, GnRH antagonist rather than GnRH agonist may be a promising option in patients with high risk of cerebral infarction as in the present case, but whether the risk of thromboembolism is truly lower with GnRH antagonist in benign gynecological diseases requires further evidence in a large number of cases. However, whether the use of GnRH antagonists is truly associated with a lower risk of thromboembolism in benign gynecological diseases requires further evidence from a large number of patients. [Adv Obstet Gynecol, 74(1) : 27-31, 2022 (R4.2)]</p>

    DOI： 10.11437/sanpunosinpo.74.27

    CiNii Article

  • Efficacy and safety of maintenance therapy using bevacizumab for advanced ovarian cancer

    NAKAJIMA Asami, FUKUDA Takeshi, SHIBATA Satoshi, AWAZU Yuichiro, NANNO Shigenori, SUEKANE Tomoki, IMAI Kenji, YAMAUCHI Makoto, KASAI Mari, ICHIMURA Tomoyuki, YASUI Tomoyo, SUMI Toshiyuki

    ADVANCES IN OBSTETRICS AND GYNECOLOGY   74 ( 4 )   509 - 514   2022（ ISSN:03708446 ）

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  • Uterine metastasis of lobular breast carcinoma under tamoxifen therapy: A case report.

    Awazu Y, Fukuda T, Imai K, Yamauchi M, Kasai M, Ichimura T, Yasui T, Sumi T

    Molecular and clinical oncology   15 ( 6 )   266   2021.12（ ISSN:2049-9450 ）

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  • T-box 2 expression is a useful indicator of the response to neoadjuvant chemotherapy for patients with locally advanced uterine cervical squamous cell carcinoma.

    Inoue Y, Fukuda T, Nanno S, Awazu Y, Shimomura M, Matsubara H, Yamauchi M, Yasui T, Sumi T

    Oncology letters   22 ( 5 )   755   2021.11（ ISSN:1792-1074 ）

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  • Massive ovarian edema with paraovarian cyst torsion treated with laparoscopic surgery: A case report.

    Fukuda T, Imai K, Yamauchi M, Kasai M, Ichimura T, Yasui T, Sumi T

    Medicine international   1 ( 5 )   17   2021.11（ ISSN:2754-3242 ）

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  • Neutrophil-to-lymphocyte ratio is associated with sensitivity to platinum-based chemotherapy and prognosis in patients with advanced serous ovarian carcinoma.

    Fukuda T, Kawanishi M, Awazu Y, Nanno S, Shimomura M, Inoue Y, Matsubara H, Yamauchi M, Kasai M, Hashiguchi Y, Ichimura T, Yasui T, Sumi T

    Molecular and clinical oncology   15 ( 4 )   217   2021.10（ ISSN:2049-9450 ）

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  • 当院における75歳以上の高齢子宮体がん患者に対する治療

    菊池 太貴, 橋口 裕紀, 山内 真, 笠井 真理, 福田 武史, 市村 友季, 安井 智代, 角 俊幸

    産婦人科の進歩   73 ( 4 )   382 - 383   2021.10（ ISSN:0370-8446 ）

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    当院における75歳以上の高齢子宮体癌患者に対する治療について、2015年1月〜2019年12月に当院で入院加療を行った当該患者44例(75歳〜92歳)を対象に検討した。その結果、44例中40例に手術を施行し、全例に単純子宮全摘出術、両側付属器摘出術を行い、再発中リスク群16例のうち9例では術後化学療法を施行しなかった。術後化学療法を施行しなかった9例中再発例は2例(22%)で、75歳未満の中リスク群で術後化学療法をしなかった5例における再発率(20%)と大差なく、75歳以上の子宮体癌中リスク群においても、術後化学療法を施行しない選択肢も考慮してよいと考えられた。

  • Effectiveness of nivolumab affected by prior cetuximab use and neck dissection in Japanese patients with recurrent or metastatic head and neck cancer: results from a retrospective observational study in a real-world setting

    Kariya S.

    International Journal of Clinical Oncology   26 ( 6 )   1049 - 1056   2021.06（ ISSN:13419625 ）

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  • Effectiveness and safety of nivolumab in patients with head and neck cancer in Japanese real-world clinical practice: a multicenter retrospective clinical study

    Hanai N.

    International Journal of Clinical Oncology   26 ( 3 )   494 - 506   2021.03（ ISSN:13419625 ）

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  • PRMT1 expression predicts response to neoadjuvant chemotherapy for locally advanced uterine cervical cancer Reviewed

    Shimomura Masahiro, Fukuda Takeshi, Awazu Yuichiro, Nanno Shigenori, Inoue Yuta, Matsubara Hiroaki, Yamauchi Makoto, Yasui Tomoyo, Sumi Toshiyuki

    ONCOLOGY LETTERS   21 ( 2 )   150   2021.02（ ISSN:1792-1074 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.3892/ol.2020.12411

    PubMed

  • PRMT1 expression predicts sensitivity to platinum-based chemotherapy in patients with ovarian serous carcinoma Reviewed

    Matsubara Hiroaki, Fukuda Takeshi, Awazu Yuichiro, Nanno Shigenori, Shimomura Masahiro, Inoue Yuta, Yamauchi Makoto, Yasui Tomoyo, Sumi Toshiyuki

    ONCOLOGY LETTERS   21 ( 2 )   162   2021.02（ ISSN:1792-1074 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.3892/ol.2020.12423

    PubMed

  • 画像検査から微小な奇形腫を疑い腹腔鏡下手術を行った卵巣未熟奇形腫に伴う抗NMDA受容体脳炎の1例 Reviewed

    山内 真, 南野 成則, 下村 将央, 今井 健至, 福田 武史, 市村 友季, 安井 智代, 角 俊幸

    「産婦人科の進歩」編集室　産婦人科の進歩   73 ( 1 )   68 - 72   2021.02（ ISSN:0370-8446 ）

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    Publishing type：Research paper (scientific journal)  

    抗NMDA受容体脳炎は2007年にDalmauによって提唱された若年女性に好発する自己免疫性辺縁系脳炎であり、腫瘍、とくに卵巣奇形腫に随伴することが多い。今回、明らかな卵巣腫大は認めなかったが、抗NMDA受容体抗体が陽性であり、画像検査にて右卵巣にわずかに脂肪成分を疑う部位を認めたため腹腔鏡手術を施行し、卵巣奇形腫の診断に至った症例を経験したので報告する。19歳1妊未産の女性。当院に入院する11日前から感冒症状が出現。入院4日前の夕に異常行動と全身痙攣を認め前医救急搬送となった。頭部MRIに異常所見は認められなかったが、意識障害の進行と不随意運動を認め脳炎が疑われたため当院神経内科へ紹介となった。その後、ICUへ入室し人工呼吸器管理となった。頭部造影MRIで大脳辺縁系にT2WI高信号域を認め、辺縁系脳炎と考えられた。入院後7日目に抗NMDA受容体抗体が検出され、骨盤部MRIとCTを撮像も明らかな卵巣の腫大は認めなかったが、微小な奇形腫の可能性も考慮し当科紹介となった。当科にて再度MRIと造影CTを撮影したところ、右卵巣に明確ではないがごくわずかに脂肪成分を疑う部位を偶発的に認めたため、腹腔鏡下右付属器摘出術を施行し右卵巣内に割を入れたところ、ごくわずかな脂肪組織を含む腫瘍(大きさ3mm)を認め、摘出標本の病理検査結果は未熟奇形腫grade 1であった。その後、人工呼吸器を離脱し徐々に意識状態は改善した。今回われわれは、微小な卵巣未熟奇形腫に伴う抗NMDA受容体脳炎に対して画像検査を重ねることで微小な病変を疑い、腹腔鏡手術に踏み切り診断と回復に至った1例を経験した。抗NMDA受容体脳炎は意識障害や呼吸障害など重篤な臨床経過をたどることが多く、画像上検出が困難な微小な腫瘍でも本疾患を発症する可能性があることを念頭において、複数回の画像検査実施あるいは撮影条件を変更して画像検査を再検討する必要があると考えられた。(著者抄録)

  • PRMT1 expression predicts sensitivity to platinum-based chemotherapy in patients with ovarian serous carcinoma.

    Matsubara H, Fukuda T, Awazu Y, Nanno S, Shimomura M, Inoue Y, Yamauchi M, Yasui T, Sumi T

    Oncology letters   21 ( 2 )   162   2021.02（ ISSN:1792-1074 ）

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  • PRMT1 expression predicts response to neoadjuvant chemotherapy for locally advanced uterine cervical cancer.

    Shimomura M, Fukuda T, Awazu Y, Nanno S, Inoue Y, Matsubara H, Yamauchi M, Yasui T, Sumi T

    Oncology letters   21 ( 2 )   150   2021.02（ ISSN:1792-1074 ）

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  • 画像検査から微小な奇形腫を疑い腹腔鏡下手術を行った卵巣未熟奇形腫に伴う抗NMDA受容体脳炎の1例

    山内 真, 南野 成則, 下村 将央, 今井 健至, 福田 武史, 市村 友季, 安井 智代, 角 俊幸

    産婦人科の進歩   73 ( 1 )   68 - 72   2021.02（ ISSN:0370-8446 ）

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    抗NMDA受容体脳炎は2007年にDalmauによって提唱された若年女性に好発する自己免疫性辺縁系脳炎であり、腫瘍、とくに卵巣奇形腫に随伴することが多い。今回、明らかな卵巣腫大は認めなかったが、抗NMDA受容体抗体が陽性であり、画像検査にて右卵巣にわずかに脂肪成分を疑う部位を認めたため腹腔鏡手術を施行し、卵巣奇形腫の診断に至った症例を経験したので報告する。19歳1妊未産の女性。当院に入院する11日前から感冒症状が出現。入院4日前の夕に異常行動と全身痙攣を認め前医救急搬送となった。頭部MRIに異常所見は認められなかったが、意識障害の進行と不随意運動を認め脳炎が疑われたため当院神経内科へ紹介となった。その後、ICUへ入室し人工呼吸器管理となった。頭部造影MRIで大脳辺縁系にT2WI高信号域を認め、辺縁系脳炎と考えられた。入院後7日目に抗NMDA受容体抗体が検出され、骨盤部MRIとCTを撮像も明らかな卵巣の腫大は認めなかったが、微小な奇形腫の可能性も考慮し当科紹介となった。当科にて再度MRIと造影CTを撮影したところ、右卵巣に明確ではないがごくわずかに脂肪成分を疑う部位を偶発的に認めたため、腹腔鏡下右付属器摘出術を施行し右卵巣内に割を入れたところ、ごくわずかな脂肪組織を含む腫瘍(大きさ3mm)を認め、摘出標本の病理検査結果は未熟奇形腫grade 1であった。その後、人工呼吸器を離脱し徐々に意識状態は改善した。今回われわれは、微小な卵巣未熟奇形腫に伴う抗NMDA受容体脳炎に対して画像検査を重ねることで微小な病変を疑い、腹腔鏡手術に踏み切り診断と回復に至った1例を経験した。抗NMDA受容体脳炎は意識障害や呼吸障害など重篤な臨床経過をたどることが多く、画像上検出が困難な微小な腫瘍でも本疾患を発症する可能性があることを念頭において、複数回の画像検査実施あるいは撮影条件を変更して画像検査を再検討する必要があると考えられた。(著者抄録)

  • Does clinical sequencing bridge to clinical benefit in cancer treatment? Reviewed

    Nishimura Sadaaki, Kato Minoru, Kimura Kenjiro, Nagahara Hisashi, Muguruma Kazuya, Lee Shigeru, Takashima Tsutomu, Kubo Shoji, Ohira Masaichi, Yashiro Masakazu, Sugimoto Atsushi, Kushiyama Shuhei, Togano Shingo, Kuroda Kenji, Yamauchi Makoto, Sumi Toshiyuki, Kaneda Hiroyasu, Kawaguchi Tomoya

    Japanese Society for Molecular Tumor Marker Research, Japan Journal of Molecular Tumor Marker Research   36 ( 0 )   5 - 6   2021

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.11241/jsmtmr.36.5

    CiNii Article

  • Slip coefficient of 90-year-old riveted joint surface with red lead paint for corrosion

    Chen Y.

    IABSE Congress, Ghent 2021: Structural Engineering for Future Societal Needs   598 - 604   2021

  • Clinical benefit for clinical sequencing using cancer panel testing.

    Nishimura S, Sugimoto A, Kushiyama S, Togano S, Kuroda K, Yamamoto Y, Yamauchi M, Sumi T, Kaneda H, Kawaguchi T, Kato M, Tagami M, Oebisu N, Hoshi M, Kimura K, Kubo S, Muguruma K, Takashima T, Ohira M, Yashiro M

    PloS one   16 ( 2 )   e0247090   2021

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  • A method for replacing lower flange splice plate of a steel I-girder connection using BPL

    Matsui S.

    IABSE Congress, Ghent 2021: Structural Engineering for Future Societal Needs   1754 - 1760   2021

  • Does clinical sequencing bridge to clinical benefit in cancer treatment?

    Nishimura Sadaaki, Sugimoto Atsushi, Kushiyama Shuhei, Togano Shingo, Kuroda Kenji, Yamauchi Makoto, Sumi Toshiyuki, Kaneda Hiroyasu, Kawaguchi Tomoya, Kato Minoru, Kimura Kenjiro, Nagahara Hisashi, Muguruma Kazuya, Lee Shigeru, Takashima Tsutomu, Kubo Shoji, Ohira Masaichi, Yashiro Masakazu

    Japan Journal of Molecular Tumor Marker Research   36 ( 0 )   5 - 6   2021

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  • Clinical treatment of 75 years and over patients with endometrial cancer

    KIKUCHI Taiki, HASHIGUCHI Yasunori, YAMAUCHI Makoto, KASAI Mari, FUKUDA Takeshi, ICHIMURA Tomoyuki, YASUI Tomoyo, SUMI Toshiyuki

    ADVANCES IN OBSTETRICS AND GYNECOLOGY   73 ( 4 )   382 - 383   2021（ ISSN:03708446 ）

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  • Atypical endometrial hyperplasia in endometrial polyp diagnosed with resectoscope: A case report

    Nakajima Asami, Ichimura Tomoyuki, Kasai Mari, Yamauchi Makoto, Hashiguchi Yasunori, Yasui Tomoyo, Tamura Kazutomi, Sumi Toshiyuki

    JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY   37 ( 1 )   149 - 153   2021（ ISSN:18849938 ）

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    <p>  Preoperative diagnosis of small uterine endometrial lesions by endometrial curettage biopsy can be difficult because tissue from localized lesions may not be obtained by this procedure. We here report a case of atypical endometrial hyperplasia in an endometrial polyp that was not diagnosed by several endometrial curettage biopsies but was finally diagnosed by resectoscopic partial resection. A 54-year-old woman, gravida 2, para 2 was referred to our hospital because cervical cytology had shown atypical glandular cells-favoring neoplasia. Cervical and endometrial biopsies obtained in our hospital yielded only normal tissue and MRI examination showed no obvious abnormalities. Hysteroscopy revealed a polypoid lesion near the ostium of the left fallopian tube, prompting repeat endometrial curettage biopsy. However, it proved difficult to collect a sample from that polypoid lesion, which was therefore removed via a resectoscope. Histological examination of the specimen thus obtained resulted in a diagnosis of atypical endometrial hyperplasia in an endometrial polyp. Abdominal simple total hysterectomy and bilateral salpingo-oophorectomy was therefore performed. The final pathological diagnosis was also atypical endometrial hyperplasia. We therefore suggest that removal of specimens via a resectoscope may be a useful means of diagnosing endometrial lesions from which it is difficult to collect tissue by endometrial curettage.</p>

    DOI： 10.5180/jsgoe.37.1_149

    CiNii Article

  • レゼクトスコープを用いて診断したatypical endometrial hyperplasia in endometrial polypの1例

    中島 安紗海, 市村 友季, 笠井 真理, 山内 真, 橋口 裕紀, 安井 智代, 田村 一富, 角 俊幸

    日本産科婦人科内視鏡学会雑誌   37 ( 1 )   149 - 153   2021（ ISSN:1884-9938 ）

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    症例は2妊2産の54歳女性で、健診の子宮頸部診異常を主訴とした。コルポスコピー観察下の子宮頸管内膜生検、子宮体部内膜生検で診断に至らず、子宮鏡検査で左卵管口付近に10mm大のポリープを認めた。子宮頸管内膜生検を行ったが、判定不可であった。頸部細胞診異常の原因は左卵管口のポリープであるが、10mmとサイズが小さく、掻爬生検では採取されないため、レゼクトスコープを用いてポリープを切除した。術中、子宮穿孔や術後の感染症などの合併症は発生しなかった。摘出したポリープの病理診断はatypical endometrial hyperplasia in endometrial polypであった。腹式単純子宮全摘術と両側付属器摘出術を追加し、病理検査で左卵管口付近の切り出し検体から軽度核異型を伴う腺管を僅かに認めた。それ以外の部位に腫瘍性病変はみられなかった。最終的に子宮体部のatypical endometrial hyperplasia in endometrial polypと診断した。

  • Tuberculous peritonitis with elevated serum CA125 levels mimicking peritoneal cancer

    Taniwaki A.

    Clinical and Experimental Obstetrics and Gynecology   47 ( 6 )   994 - 996   2020.12（ ISSN:03906663 ）

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  • 卵巣成熟奇形腫の術前診断で手術を行うも子宮腫瘍と判明し腹腔鏡下子宮全摘出術を行った脂肪平滑筋腫の1例

    市村 友季, 笠井 真理, 下村 将央, 山内 真, 福田 武史, 橋口 裕紀, 安井 智代, 角 俊幸

    日本産科婦人科内視鏡学会雑誌   36 ( 2 )   198 - 203   2020.12（ ISSN:1884-9938 ）

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    症例は71歳3妊3産で、画像所見より左卵巣成熟奇形腫を疑って腹腔鏡下両側付属器摘出術を開始したところ、漿膜下に子宮腫瘍および腹膜に癒着した左卵巣を認めた。術中所見およびMRI所見より子宮脂肪平滑筋腫と判断し、腹腔鏡下単純子宮全摘術および両側付属器摘出術を行った。

  • Secondary small cell vaginal cancer after operative therapy for endometrial cancer

    Shimazaki I.

    European Journal of Gynaecological Oncology   41 ( 5 )   821 - 823   2020.10（ ISSN:03922936 ）

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  • Photoluminescence On/Off Switching of a Single Colloidal Quantum Dot Using Photochromic Diarylethene

    Yano N.

    Journal of Physical Chemistry C   124 ( 31 )   17423 - 17429   2020.08（ ISSN:19327447 ）

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  • The Laterally Extended Paramedian Forehead Flap for Nasal Reconstruction: The Delay Technique Revisited.

    Itani Y, Yotsuyanagi T, Yamauchi M, Sugai A, Kato S, Yamashita K, Isogai N

    Plastic and reconstructive surgery. Global open   8 ( 6 )   e2871   2020.06

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  • 18F-fluorodeoxyglucose(18F-FDG)positron emission tomography(PET、18F-PET)検査陽性で、男化現象を示さなかったため診断に苦慮した良性のステロイド細胞腫瘍の1例 Reviewed

    梅咲 直彦, 山内 真, 中野 雄介, 深山 雅人, 井上 裕, 松田 真希子, 沖村 明

    「産婦人科の進歩」編集室　産婦人科の進歩   72 ( 2 )   88 - 95   2020.05（ ISSN:0370-8446 ）

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    Publishing type：Research paper (scientific journal)  

    30歳前半、女性。無月経を主訴に前医を受診し、右卵巣腫瘍を指摘され、当院へ紹介となった。MRI、18F-PET検査より当初、充実性の卵巣腫瘍で悪性が疑われたが、年齢や無月経歴から卵巣性索間質性腫瘍の可能性も考え、内分泌検査を行った結果、テストステロンの高値が判明した。男化現象は認められなかったが、テストステロン産生の性索間質性腫瘍も鑑別に加えて試験開腹術を施行したところ、病理組織学的に良性の卵巣ステロイド細胞腫瘍と確定診断された。術後は月経が再開し、術後27ヵ月現在、良好に経過している。

  • 18F-fluorodeoxyglucose(18F-FDG)positron emission tomography(PET、18F-PET)検査陽性で、男化現象を示さなかったため診断に苦慮した良性のステロイド細胞腫瘍の1例

    梅咲 直彦, 山内 真, 中野 雄介, 深山 雅人, 井上 裕, 松田 真希子, 沖村 明

    産婦人科の進歩   72 ( 2 )   88 - 95   2020.05（ ISSN:0370-8446 ）

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    30歳前半、女性。無月経を主訴に前医を受診し、右卵巣腫瘍を指摘され、当院へ紹介となった。MRI、18F-PET検査より当初、充実性の卵巣腫瘍で悪性が疑われたが、年齢や無月経歴から卵巣性索間質性腫瘍の可能性も考え、内分泌検査を行った結果、テストステロンの高値が判明した。男化現象は認められなかったが、テストステロン産生の性索間質性腫瘍も鑑別に加えて試験開腹術を施行したところ、病理組織学的に良性の卵巣ステロイド細胞腫瘍と確定診断された。術後は月経が再開し、術後27ヵ月現在、良好に経過している。

  • Squamous cell carcinomas arising from relapsing blaschkolinear dermatosis.

    Oiso N, Itani Y, Yanagihara S, Okahashi K, Yamauchi M, Isogai N, Kawada A

    The Journal of dermatology   47 ( 4 )   e124 - e125   2020.04（ ISSN:0385-2407 ）

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  • Difficult diagnosis in a patient with no virilizing symptoms of a benign ovarian steroid cell tumor that showed high <sup>18</sup>F-fluorodeoxyglucose (<sup>18</sup>F-FDG) uptake by positron emission tomography (<sup>18</sup>F-PET) Reviewed

    UMESAKI Naohiko, YAMAUCHI Makoto, NAKANO Yusuke, MIYAMA Masato, INOUE Yutaka, MATSUDA Makiko, OKIMURA Akira

    THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, ADVANCES IN OBSTETRICS AND GYNECOLOGY   72 ( 2 )   88 - 95   2020（ ISSN:0370-8446 ）

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    Publishing type：Research paper (scientific journal)  

    <p>Ovarian steroid cell tumors (SCTs) are rare and account for 0.1% of ovarian tumors. Among patients affected by tumors, 56-77% have virilizing symptoms. This symptom is useful for detecting of SCT. The patient in the present study did not show any virilizing symptoms. Therefore, diagnosis of an SCT was difficult. Magnetic resonance imaging showed a heterogenous mass on T2-weighted imaging and hyperintensity on diffusion-weighted imaging in the right ovary. 18F-fluorodeoxyglucose (<sup>18</sup>F-FDG) positron emission tomography showed high <sup>18</sup>F-FDG uptake (maximal standardized uptake value (SUV max) :17). Therefore, ovarian cancer was suspected. Before surgery, we measured testosterone levels to determine the possibility of ovarian sex cord-stromal tumor because she had amenorrhea for nine months and had a solid ovarian tumor. Exploratory laparotomy was performed for diagnosis of ovarian cancer or a sex cord-stromal tumor because the testosterone level was high. Intraoperative frozen section analysis showed a benign sex cord-stromal tumor and R oophorectomy was then performed. Histomorphology and immunohistochemistry of the tumor suggested the diagnosis of a benign ovarian SCT. Postoperatively, testosterone levels became normal in 1 week and menstruation appeared in 1 month. The patient continued to have a regular menstrual cycle and good health for 30 months. [Adv Obstet Gynecol, 72(2) : 88-95, 2020 (R2.5)]</p>

    DOI： 10.11437/sanpunosinpo.72.88

    CiNii Article

  • Anti-NMDAreceptorencephalitiswithamicro,undetectableovarianimmature teratoma that led to a definitive diagnosis by laparoscopic surgery Reviewed

    YAMAUCHI Makoto, NANNO Shigenori, SHIMOMURA Masahiro, IMAI Kenji, FUKUDA Takeshi, ICHIMURA Tomoyuki, YASUI Tomoyo, SUMI Toshiyuki

    THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, ADVANCES IN OBSTETRICS AND GYNECOLOGY   73 ( 1 )   68 - 72   2020（ ISSN:0370-8446 ）

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    Publishing type：Research paper (scientific journal)  

    <p>Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune limbic encephalitis that is prevalent in young women with ovarian teratoma. In the present study, we report a case of symptomatic improvement after laparoscopic right salpingo-oophorectomy for anti-NMDA receptor antibody encephalitis associated with a micro ovarian immature teratoma without obvious ovarian enlargement on imaging. A 19-year-old woman was admitted due to seizures to our hospital. She was transferred to our neurology department due to the progression of disorientation and involuntary movements, and encephalitis was suspected. Seventh day of hospitalization, anti-NMDA receptor antibodies were found to be positive. MRI and CT showed an area in the right ovary that was undefined but very faintly suspicious of fatty components, suggesting the presence of a micro ovarian teratoma. The patient underwent a laparoscopic right salpingo-oophorectomy. Pathological examination was immature teratoma, Grade1. Macroscopically, a right ovarian tumor (three mm in size) containing a small amount of fatty tissue was observed. The patient was weaned off the respirator on the fourth postoperative day. Her conscious level gradually improved and she was able to communicate. Careful scrutiny is necessary, bearing in mind that even microscopic teratomas that are difficult to detect on imaging can cause the disease. [Adv Obstet Gynecol, 73 (1) : 68-72, 2021 (R3.2)]</p>

    DOI： 10.11437/sanpunosinpo.73.68

    CiNii Article

  • A case of lipoleiomyoma, preoperatively diagnosed as ovarian mature teratoma, treated with total laparoscopic hysterectomy Reviewed

    Ichimura Tomoyuki, Kasai Mari, Shimomura Masahiro, Yamauchi Makoto, Fukuda Takeshi, Hashiguchi Yasunori, Yasui Tomoyo, Sumi Toshiyuki

    JAPAN SOCIETY OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY AND MINIMALLY INVASIVE THERAPY, JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY   36 ( 2 )   198 - 203   2020（ ISSN:1884-9938 ）

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    Publishing type：Research paper (scientific journal)  

    <p>  Ovarian mature teratomas present various risks, such as acute abdomen, and hence surgery is the usual protocol. On the other hand, uterine lipoleiomyoma is a variant of uterine leiomyoma, and surgery is not always performed in postmenopausal cases. We report a case of postmenopausal uterine lipoleiomyoma, preoperatively diagnosed as ovarian mature teratoma, and treated surgically. A 71-year-old woman presented a 5.5-cm mass on the left dorsal side of the uterus that was fat suppressed on magnetic resonance imaging. The preoperative diagnosis was mature teratoma of the left ovary.</p><p>  Laparoscopic bilateral salpingo-oophorectomy was planned, but we changed the operative procedure to laparoscopic hysterectomy and bilateral salpingo-oophorectomy. This was because the mass was identified as a uterine mass as no swelling was observed in either ovary during surgery. Pathological examination of the excised specimen revealed lipoleiomyoma. It may be difficult to distinguish uterine lipoleiomyomas from ovarian mature teratomas when the lipoleiomyomas are subserosal. In this case, the tumor was presumed to have originated from the uterus based on the findings of the pelvic examination, and we were able to discuss the operative procedure options in advance. One of the merits of laparoscopic surgery in this case was that the burden of changing the surgical procedure was less than that with laparotomy; however, at the same time, preoperative exclusion of malignant disease was considered important. In the diagnosis of tumors containing fat, the differential diagnosis of lipoleiomyoma should be considered.</p><p></p>

    DOI： 10.5180/jsgoe.36.2_198

    CiNii Article

  • High-redshift gamma-ray burst for unraveling the Dark Ages Mission - HiZ-GUNDAM -

    Yonetoku D.

    Proceedings of SPIE - The International Society for Optical Engineering   11444   2020（ ISSN:0277786X ） （ ISBN:9781510636750 ）

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  • Difficult diagnosis in a patient with no virilizing symptoms of a benign ovarian steroid cell tumor that showed high <sup>18</sup>F-fluorodeoxyglucose (<sup>18</sup>F-FDG) uptake by positron emission tomography (<sup>18</sup>F-PET)

    UMESAKI Naohiko, YAMAUCHI Makoto, NAKANO Yusuke, MIYAMA Masato, INOUE Yutaka, MATSUDA Makiko, OKIMURA Akira

    ADVANCES IN OBSTETRICS AND GYNECOLOGY   72 ( 2 )   88 - 95   2020（ ISSN:03708446 ）

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    <p>Ovarian steroid cell tumors (SCTs) are rare and account for 0.1% of ovarian tumors. Among patients affected by tumors, 56-77% have virilizing symptoms. This symptom is useful for detecting of SCT. The patient in the present study did not show any virilizing symptoms. Therefore, diagnosis of an SCT was difficult. Magnetic resonance imaging showed a heterogenous mass on T2-weighted imaging and hyperintensity on diffusion-weighted imaging in the right ovary. 18F-fluorodeoxyglucose (<sup>18</sup>F-FDG) positron emission tomography showed high <sup>18</sup>F-FDG uptake (maximal standardized uptake value (SUV max) :17). Therefore, ovarian cancer was suspected. Before surgery, we measured testosterone levels to determine the possibility of ovarian sex cord-stromal tumor because she had amenorrhea for nine months and had a solid ovarian tumor. Exploratory laparotomy was performed for diagnosis of ovarian cancer or a sex cord-stromal tumor because the testosterone level was high. Intraoperative frozen section analysis showed a benign sex cord-stromal tumor and R oophorectomy was then performed. Histomorphology and immunohistochemistry of the tumor suggested the diagnosis of a benign ovarian SCT. Postoperatively, testosterone levels became normal in 1 week and menstruation appeared in 1 month. The patient continued to have a regular menstrual cycle and good health for 30 months. [Adv Obstet Gynecol, 72(2) : 88-95, 2020 (R2.5)]</p>

    DOI： 10.11437/sanpunosinpo.72.88

    CiNii Article

  • A case of lipoleiomyoma, preoperatively diagnosed as ovarian mature teratoma, treated with total laparoscopic hysterectomy

    Ichimura Tomoyuki, Kasai Mari, Shimomura Masahiro, Yamauchi Makoto, Fukuda Takeshi, Hashiguchi Yasunori, Yasui Tomoyo, Sumi Toshiyuki

    JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY   36 ( 2 )   198 - 203   2020（ ISSN:18849938 ）

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    <p>  Ovarian mature teratomas present various risks, such as acute abdomen, and hence surgery is the usual protocol. On the other hand, uterine lipoleiomyoma is a variant of uterine leiomyoma, and surgery is not always performed in postmenopausal cases. We report a case of postmenopausal uterine lipoleiomyoma, preoperatively diagnosed as ovarian mature teratoma, and treated surgically. A 71-year-old woman presented a 5.5-cm mass on the left dorsal side of the uterus that was fat suppressed on magnetic resonance imaging. The preoperative diagnosis was mature teratoma of the left ovary.</p><p>  Laparoscopic bilateral salpingo-oophorectomy was planned, but we changed the operative procedure to laparoscopic hysterectomy and bilateral salpingo-oophorectomy. This was because the mass was identified as a uterine mass as no swelling was observed in either ovary during surgery. Pathological examination of the excised specimen revealed lipoleiomyoma. It may be difficult to distinguish uterine lipoleiomyomas from ovarian mature teratomas when the lipoleiomyomas are subserosal. In this case, the tumor was presumed to have originated from the uterus based on the findings of the pelvic examination, and we were able to discuss the operative procedure options in advance. One of the merits of laparoscopic surgery in this case was that the burden of changing the surgical procedure was less than that with laparotomy; however, at the same time, preoperative exclusion of malignant disease was considered important. In the diagnosis of tumors containing fat, the differential diagnosis of lipoleiomyoma should be considered.</p><p></p>

    DOI： 10.5180/jsgoe.36.2_198

    CiNii Article

  • Anti-NMDAreceptorencephalitiswithamicro,undetectableovarianimmature teratoma that led to a definitive diagnosis by laparoscopic surgery

    YAMAUCHI Makoto, NANNO Shigenori, SHIMOMURA Masahiro, IMAI Kenji, FUKUDA Takeshi, ICHIMURA Tomoyuki, YASUI Tomoyo, SUMI Toshiyuki

    ADVANCES IN OBSTETRICS AND GYNECOLOGY   73 ( 1 )   68 - 72   2020（ ISSN:03708446 ）

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    <p>Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune limbic encephalitis that is prevalent in young women with ovarian teratoma. In the present study, we report a case of symptomatic improvement after laparoscopic right salpingo-oophorectomy for anti-NMDA receptor antibody encephalitis associated with a micro ovarian immature teratoma without obvious ovarian enlargement on imaging. A 19-year-old woman was admitted due to seizures to our hospital. She was transferred to our neurology department due to the progression of disorientation and involuntary movements, and encephalitis was suspected. Seventh day of hospitalization, anti-NMDA receptor antibodies were found to be positive. MRI and CT showed an area in the right ovary that was undefined but very faintly suspicious of fatty components, suggesting the presence of a micro ovarian teratoma. The patient underwent a laparoscopic right salpingo-oophorectomy. Pathological examination was immature teratoma, Grade1. Macroscopically, a right ovarian tumor (three mm in size) containing a small amount of fatty tissue was observed. The patient was weaned off the respirator on the fourth postoperative day. Her conscious level gradually improved and she was able to communicate. Careful scrutiny is necessary, bearing in mind that even microscopic teratomas that are difficult to detect on imaging can cause the disease. [Adv Obstet Gynecol, 73 (1) : 68-72, 2021 (R3.2)]</p>

    DOI： 10.11437/sanpunosinpo.73.68

    CiNii Article

  • Status of X-Ray imaging and spectroscopy mission (XRISM)

    Tashiro M.

    Proceedings of SPIE - The International Society for Optical Engineering   11444   2020（ ISSN:0277786X ） （ ISBN:9781510636750 ）

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  • Ovarian actinomycosis mimicking ovarian malignant tumor with no history of intra-uterine device: A rare case

    Oki E.

    Clinical and Experimental Obstetrics and Gynecology   46 ( 6 )   1011 - 1013   2019.12（ ISSN:03906663 ）

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  • Establishment of a Standardized Technique for Concha-type Microtia-How to Incorporate the Cartilage Frame into the Remnant Ear.

    Yotsuyanagi T, Yamashita K, Yamauchi M, Nakagawa T, Sugai A, Kato S, Gonda A, Suzuki A, Onuma M

    Plastic and reconstructive surgery. Global open   7 ( 7 )   e2337   2019.07

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  • Bevacizumab for ovarian cancer Reviewed

    YAMAUCHI Makoto

    THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, ADVANCES IN OBSTETRICS AND GYNECOLOGY   71 ( 1 )   51 - 55   2019（ ISSN:0370-8446 ）

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    Publishing type：Research paper (scientific journal)   Kind of work：Single Work  

    DOI： 10.11437/sanpunosinpo.71.51

    CiNii Article

  • Ovarian actinomycosis mimicking ovarian malignant tumor with no history of intra-uterine device: a rare case Reviewed

    Oki E., Hashiguchi Y., Yamauchi M., Kasai M., Fukuda T., Ichimura T., Yasui T., Sumi T.

    CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY   46 ( 6 )   1011 - 1013   2019（ ISSN:0390-6663 ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.12891/ceog4900.2019

  • Bevacizumab for ovarian cancer

    YAMAUCHI Makoto

    ADVANCES IN OBSTETRICS AND GYNECOLOGY   71 ( 1 )   51 - 55   2019（ ISSN:03708446 ）

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  • Primary small cell ovarian carcinoma of the pulmonary type Reviewed

    Hashiguchi Yasunori, Yamauchi Makoto, Kasai Mari, Fukuda Takeshi, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   28   48 - 48   2018.10（ ISSN:1048-891X ）

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    Publishing type：Research paper (scientific journal)  

  • CERVICAL CLEAR CELL CARCINOMA: REPORT OF A CASE Reviewed

    Yamauchi M., Takeshi F., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   28   579 - 579   2018.09（ ISSN:1048-891X ）

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    Publishing type：Research paper (scientific journal)  

  • PROTECTIVE EFFECT OF MAGNESIUM SUPPLEMENTATION ON CISPLATIN-INDUCED RENAL TOXICITY IN PATIENTS WITH UTERINE CERVICAL CANCER Reviewed

    Inoue Y., Fukuda T., Yamauchi M., Kasai M., Hashiguchi Y., Tomoyuki I., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   28   297 - 297   2018.09（ ISSN:1048-891X ）

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  • NEUTROPHIL-TO-LYMPHOCYTE RATIO IS ASSOCIATED WITH SENSITIVITY TO PLATINUM-BASED CHEMOTHERAPY AND PROGNOSIS FOR ADVANCED OVARIAN SEROUS CARCINOMA Reviewed

    Shimomura M., Fukuda T., Yamauchi M., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   28   834 - 834   2018.09（ ISSN:1048-891X ）

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    Publishing type：Research paper (scientific journal)  

  • EVALUATION OF EFFICACY AND SAFETY OF BEVACIZUMAB FOR ADVANCE AND RECURRENT M.LLERIAN CARCINOMA IN OUR INSTITUTION Reviewed

    Matsubara H., Fukuda T., Yamauchi M., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   28   762 - 762   2018.09（ ISSN:1048-891X ）

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  • Expression of UCP2 is associated with the sensitivity to platinum-based chemotherapy for ovarian serous carcinoma Reviewed

    Inoue Yuta, Fukuda Takeshi, Kawanishi Masaru, Shimomura Masahiro, Wada Takuma, Yamauchi Makoto, Yasui Tomoyo, Sumi Toshiyuki

    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE   42   S9 - S9   2018（ ISSN:1107-3756 ）

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  • TBX2 expression is associated with platinum-sensitivity of ovarian serous carcinoma Reviewed

    Matsubara Hiroaki, Fukuda Takeshi, Shimomura Masahiro, Tasaka Reiko, Yamauchi Makoto, Yasui Tomoyo, Sumi Toshiyuki

    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE   42   S9 - S9   2018（ ISSN:1107-3756 ）

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  • 陰圧創傷閉鎖法後の慢性潰瘍の組織学的変化(Histological change of cbronic ulcers following negative-pressure wound therapy)

    Hashimoto Takahiro, Yamauchi Makoto, Isogai Noritaka, Morotomi Tadaaki, Kusuhara Hirohisa

    Acta Medica Kinki University   42 ( 2 )   43 - 47   2017.12（ ISSN:0386-6092 ）

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    陰圧創傷閉鎖法を用いて、様々な原因での潰瘍化による潰瘍性病変を治療し、組織学的変化を調べた。傷の表面を密封包帯で完全に塞ぎ、傷の表面を125mmHgの持続減圧に保った。潰瘍底の中心部から組織を採取して、肉眼的・組織学的に評価した。この方法を用いたところ、潰瘍の原因に依らず、浮腫、好中球浸潤、毛細血管形成と創底から垂直に伸びるコラーゲン線維の改善が観察された。組織検査結果でも慢性の潰瘍において良好な肉芽形成が生じていた。この方法では、装置を適用している間、減圧の負荷と感染状態を監視する必要があるが、簡便で侵襲性が低く、効果的な方法であると考えられた。

  • Expression of epidermal growth factor-like domain 7 may be a predictive marker of the effect of neoadjuvant chemotherapy for locally advanced uterine cervical cancer Reviewed

    Yamauchi Makoto, Fukuda Takeshi, Wada Takuma, Kawanishi Masaru, Imai Kenji, Tasaka Reiko, Yasui Tomoyo, Sumi Toshiyuki

    ONCOLOGY LETTERS   12 ( 6 )   5183 - 5189   2016.12（ ISSN:1792-1074 ）

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    DOI： 10.3892/ol.2016.5318

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  • Pharmacokinetic analyses of carboplatin in a patient with cancer of the fallopian tubes undergoing hemodialysis: A case report Reviewed

    Wada Takuma, Fukuda Takeshi, Kawanishi Masaru, Tasaka Reiko, Imai Kenji, Yamauchi Makoto, Kasai Mari, Hashiguchi Yasunori, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    BIOMEDICAL REPORTS   5 ( 2 )   199 - 202   2016.08（ ISSN:2049-9434 ）

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    DOI： 10.3892/br.2016.714

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  • IS-MW-4-3 Expression of UCP2 predicts the efficacy of neoadjuvant chemotherapy for locally advanced uterine cervical cancer(Group 4 Oncology 2,International Session Mini Workshop) : Reviewed

    Imai Kenji, Fukuda Takeshi, Wada Takuma, Kawanishi Masaru, Tasaka Reiko, Yamauchi Makoto, Kasai Mari, Hashiguchi Yasunori, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    日本産科婦人科学会　日本産科婦人科學會雜誌   68 ( 2 )   2016

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    CiNii Article

  • ISP-4-5 The retrospective analysis of the patients with positive surgical margin who underwent the uterine cervical conization(Group 4 Cervical Cancer 3,International Session Poster) : Reviewed

    Tasaka Reiko, Fukuda Takeshi, Wada Takuma, Kawanishi Masaru, Imai Kenji, Yamauchi Makoto, Kasai Mari, Hashiguchi Yasunori, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    日本産科婦人科学会　日本産科婦人科學會雜誌   68 ( 2 )   2016

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    CiNii Article

  • ISP-16-9 The experience of the treatment of the epithelial ovarian cancer with bevacizumab(Group 16 Ovarian Cancer 5,International Session Poster) : Reviewed

    Wada Takuma, Fukuda Takeshi, Kawanishi Masaru, Imai Kenji, Tasaka Reiko, Yamauchi Makoto, Kasai Mari, Hashiguchi Yasunori, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    日本産科婦人科学会　日本産科婦人科學會雜誌   68 ( 2 )   2016

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    CiNii Article

  • ISP-14-1 Pulmonary type of small cell carcinoma of the ovary : a case report(Group 14 Ovarian Cancer 3,International Session Poster) : Reviewed

    Kawanishi Masaru, Fukuda Takeshi, Wada Takuma, Imai Kenji, Tasaka Reiko, Yamauchi Makoto, Kasai Mari, Hashiguchi Yasunori, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    日本産科婦人科学会　日本産科婦人科學會雜誌   68 ( 2 )   2016

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    CiNii Article

  • CLINICAL ANALYSIS OF SIX PATIENTS WITH PRIMARY MALIGNANT MELANOMA IN VULVA AND VAGINA Reviewed

    Tasaka M., Fukuda T., Wada T., Kawanishi M., Imai K., Yamauchi M., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Deguchi M., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   25 ( 9 )   1676 - 1676   2015.10（ ISSN:1048-891X ）

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  • SAFETY AND EFFICACY OF DOCETAXEL PLUS CISPLATIN FOR THE PATIENTS WITH ENDOMETRIAL CANCER Reviewed

    Fukuda T., Wada T., Kawanishi M., Imai K., Tasaka R., Yamauchi M., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Deguchi M., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   25 ( 9 )   1060 - 1060   2015.10（ ISSN:1048-891X ）

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  • PEGYLATED LIPOSOMAL DOXORUBICIN FOR PLATINUM-RESISTANT OR REFRACTORY MULLERIAN CARCINOMA (EPITHELIAL OVARIAN CARCINOMA, PRIMARY CARCINOMA OF FALLOPIAN TUBE AND PERITONEAL CARCINOMA) Reviewed

    Wada T., Fukuda T., Kawanishi M., Imai K., Tasaka R., Yamauchi M., Kasai M., Hashiguchi Y., Ichimura T., Deguchi M., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   25 ( 9 )   429 - 429   2015.10（ ISSN:1048-891X ）

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  • EXPRESSION OF EGFL7 PREDICTS THE EFFICACY OF NEOADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED UTERINE CERVICAL CANCER Reviewed

    Yamauchi M., Fukuda T., Wada T., Kawanishi M., Imai K., Tasaka R., Yasui T., Deguchi M., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   25 ( 9 )   172 - 172   2015.10（ ISSN:1048-891X ）

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  • Complete recovery from paraneoplastic anti-NMDAR encephalitis associated with a small ovarian teratoma following a laparoscopic salpingo-oophorectomy: A case report Reviewed

    Imai Kenji, Fukuda Takeshi, Wada Takuma, Kawanishi Masaru, Yamauchi Makoto, Hashiguchi Yasunori, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    EXPERIMENTAL AND THERAPEUTIC MEDICINE   9 ( 5 )   1723 - 1726   2015.05（ ISSN:1792-0981 ）

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    DOI： 10.3892/etm.2015.2344

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  • Sirtuin1 expression predicts the efficacy of neoadjuvant chemotherapy for locally advanced uterine cervical cancer Reviewed

    Teramae Masatomo, Fukuda Takeshi, Wada Takuma, Kawanishi Masaru, Imai Kenji, Yamauchi Makoto, Yasui Tomoyo, Sumi Toshiyuki

    MOLECULAR AND CLINICAL ONCOLOGY   3 ( 1 )   73 - 78   2015（ ISSN:2049-9450 ）

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    DOI： 10.3892/mco.2014.427

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  • Primary peritoneal cancer: study of 14 cases and comparison with epithelial ovarian cancer Reviewed

    Fukuda T., Imai K., Yamauchi M., Teramae M., Hashiguchi Y., Ichimura T., Yasui T., Sumi T.

    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY   36 ( 1 )   49 - 53   2015（ ISSN:0392-2936 ）

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  • Minimal deviation mucinous adenocarcinoma of the uterine cervix that proved difficult to differentiate from endometrial cancer: A case report Reviewed

    Nishii Yuko, Fukuda Takeshi, Imai Kenji, Yamauchi Makoto, Hashiguchi Yasunori, Ichimura Tomoyuki, Yasui Tomoyo, Sumi Toshiyuki

    ONCOLOGY LETTERS   8 ( 6 )   2481 - 2484   2014.12（ ISSN:1792-1074 ）

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    DOI： 10.3892/ol.2014.2532

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  • CLINICAL ANALYSIS OF RECURRENT UTERINE CERVICAL CANCER AFTER SURGERY Reviewed

    Wada T., Fukuda T., Kawanishi M., Imai K., Yamauchi M., Hashiguchi Y., Kasai M., Ichimura T., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   24 ( 9 )   644 - 645   2014.11（ ISSN:1048-891X ）

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  • SAFETY AND EFFICACY OF DOCETAXEL PLUS CARBOPLATIN IN MENOPAUSAL PATIENTS WITH MULLERIAN CARCINOMA. Reviewed

    Imai K., Fukuda T., Kawanishi M., Wada T., Yamauchi M., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   24 ( 9 )   164 - 164   2014.11（ ISSN:1048-891X ）

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  • EXPRESSION OF SIRTUIN 1 PREDICTS THE EFFICACY OF NEOADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED UTERINE CERVICAL CANCER Reviewed

    Yamauchi M., Fukuda T., Wada T., Kawanishi M., Imai K., Teramae M., Tasaka R., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   24 ( 9 )   545 - 545   2014.11（ ISSN:1048-891X ）

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  • CLINICAL ANALYSIS OF STAGE I TO II ADENOSQUAMOU CARCINOMA OF UTERINE CERVIX Reviewed

    Kawanishi M., Fukuda T., Wada T., Imai K., Yamauchi M., Kasai M., Hashiguchi Y., Ichimura T., Yasui T., Sumi T.

    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER   24 ( 9 )   648 - 648   2014.11（ ISSN:1048-891X ）

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  • Comparison of outcomes between squamous cell carcinoma and adenocarcinoma in patients with surgically treated stage I-II cervical cancer. Reviewed

    Yamauchi M, Fukuda T, Wada T, Kawanishi M, Imai K, Hashiguchi Y, Ichimura T, Yasui T, Sumi T

    Molecular and clinical oncology   2 ( 4 )   518 - 524   2014.07（ ISSN:2049-9450 ）

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    DOI： 10.3892/mco.2014.295

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  • 腹式単純子宮全摘術が排尿に与える影響に関する検討 Reviewed

    山内 真, 福田 武史, 橋口 裕紀, 松本 佳也, 市村 友季, 安井 智代, 角 俊幸, 古山 将康, 石河 修

    日本女性骨盤底医学会　日本女性骨盤底医学会誌   10 ( 1 )   61 - 64   2013.12（ ISSN:2187-5669 ）

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    腹式単純子宮全摘出術後に頻尿や尿意切迫感を訴える患者が存在し活過動膀胱(OAB)と診断されることがある。そこで、腹式単純子宮全摘出術が排尿に与える影響を調査し、術後にOABが出現する頻度を検討する。2011年1月から2012年1月までに当施設で腹式単純子宮全摘術を施行した46例を対象とし、術前、術後3日目、術後7日目にそれぞれ1日の尿量、尿回数、飲水量、尿失禁の回数、尿失禁量を測定し、またOAB症状質問票(OABSS)を用いてOABの有無を診断した。術前、術後3日目、術後7日目のそれぞれの平均一日尿量は1538ml、1280ml、1537ml、平均尿回数は8.4回、7.7回、8.5回、平均飲水量は1338ml、1122ml、1261mlと術後3日目で有意に低値となった。術前、術後3日目、術後7日目のそれぞれのOABSS合計点数の平均は1.5、1.8、1.6で有意差を認めなかったが、41例中2例(4.9%)で術後にOABと診断された。頻度は低いが腹式単純子宮全摘術の合併症としてOABの存在を認識する必要があることが示唆された。(著者抄録)

  • 腹式単純子宮全摘術が排尿に与える影響に関する検討

    山内 真, 福田 武史, 橋口 裕紀, 松本 佳也, 市村 友季, 安井 智代, 角 俊幸, 古山 将康, 石河 修

    日本女性骨盤底医学会誌   10 ( 1 )   61 - 64   2013.12（ ISSN:2187-5669 ）

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    腹式単純子宮全摘出術後に頻尿や尿意切迫感を訴える患者が存在し活過動膀胱(OAB)と診断されることがある。そこで、腹式単純子宮全摘出術が排尿に与える影響を調査し、術後にOABが出現する頻度を検討する。2011年1月から2012年1月までに当施設で腹式単純子宮全摘術を施行した46例を対象とし、術前、術後3日目、術後7日目にそれぞれ1日の尿量、尿回数、飲水量、尿失禁の回数、尿失禁量を測定し、またOAB症状質問票(OABSS)を用いてOABの有無を診断した。術前、術後3日目、術後7日目のそれぞれの平均一日尿量は1538ml、1280ml、1537ml、平均尿回数は8.4回、7.7回、8.5回、平均飲水量は1338ml、1122ml、1261mlと術後3日目で有意に低値となった。術前、術後3日目、術後7日目のそれぞれのOABSS合計点数の平均は1.5、1.8、1.6で有意差を認めなかったが、41例中2例(4.9%)で術後にOABと診断された。頻度は低いが腹式単純子宮全摘術の合併症としてOABの存在を認識する必要があることが示唆された。(著者抄録)

  • Clinical and genetic analysis of microtia in Japan. Reviewed

    Yamauchi M, Yotsuyanagi T, Ikeda K, Yoshikawa M, Urushidate S, Mikami M, Kamo K

    Journal of plastic surgery and hand surgery   46 ( 5 )   330 - 4   2012.10（ ISSN:2000-656X ）

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.3109/2000656X.2012.700018

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