Updated on 2023/03/29

写真a

 
KAWAGUCHI Takashi
 
Organization
Graduate School of Agriculture Department of Applied Biological Chemistry Professor
School of Agriculture Department of Applied Biological Chemistry
Title
Professor
Affiliation
Institute of Agriculture

Position

  • Graduate School of Agriculture Department of Applied Biological Chemistry 

    Professor  2022.04 - Now

  • School of Agriculture Department of Applied Biological Chemistry 

    Professor  2022.04 - Now

Degree

  • 農学博士 ( Others )

Research Areas

  • Life Science / Applied biochemistry  / Molecular Biology

  • Life Science / Applied microbiology  / Applied Microbiology

Research subject summary

  • 微生物の有用物質・機能の検索および改良

  • 糸状菌における遺伝子発現制御機構

  • カビの生産するセルラーゼの利用

Research Career

  •  

    糖質分解酵素、酵素阻害剤、生理活性物質、スクリーニング 

  •  

    転写因子、セルラーゼ・ヘミセルラーゼ遺伝子、糸状菌による異種タンパク質生産 

  •  

    バイオ精練、紙パルプ 

  •  

    セルラーゼ・ヘミセルラーゼ、バイオエタノール、バイオリファイナリ、環境、グリーンケミストリー 

Professional Memberships

  • バイオインダストリー協会

    2003.01 - Now

  • 糸状菌分子生物学研究会

    2001.04 - Now

  • 糸状菌遺伝子研究会

    1996.04 - Now

  • セルラーゼ研究会

    1995.04 - Now

  • 日本生物工学会

    1989.04 - Now

  • 日本農芸化学会

    1982.04 - Now

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Papers

  • A new function of a putative UDP-glucose 4-epimerase on the expression of glycoside hydrolase genes in Aspergillus aculeatus Reviewed

    Mizuki Kuga, Hidetoshi Shiroyanagi, Takashi Kawaguchi & Shuji Tani

    Applied Genetics and Molecular Biotechnology   107   785 - 795   2023.01

  • Improvement of cellulosic biomass-degrading enzyme production by reducing extracellular protease production in Aspergillus aculeatus. Reviewed

    Yoshimura Y, Kobayashi Y, Kawaguchi T, Tani S

    J Gen Appl Microbiol   68 ( 3 )   143 - 150   2022.11

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    Publishing type:Research paper (scientific journal)  

  • Serine-arginine protein kinase-like protein, SrpkF, stimulates both cellobiose-responsive and D-xylose-responsive signaling pathways in Aspergillus aculeatus. Reviewed

    Katayama R, Kobayashi N, Kawaguchi T, Tani S

    Curr Genet   68 ( 1 )   143 - 152   2022.02

  • Serine-arginine protein kinase-like protein, SrpkF, stimulates both cellobiose-responsive and D-xylose-responsive signaling pathways in Aspergillus aculeatus. Reviewed

    Kayayama R, Kobayashi N, Kawaguchi T, Tani S*.

    Curr Genet. 雑誌   2021.08

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    Kind of work:Joint Work  

  • Biogenic manganese oxides combined with 1-hydroxybenzotriazol and an Mn(II)-oxidizing enzyme from Pleosporales sp. Mn1 oxidize 3,4-dimethoxytoluene to yield 3,4-dimethoxybenzaldehyde. Reviewed

    Yoshimura Y, Tani S, Fujiwara M, Nakamura M, Sumitani J, Kawaguchi T*

    Journal of Bioscience and Biotechnology 雑誌   2021.01

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    Kind of work:Joint Work  

  • A component of the septation initiation network complex, AaSepM, is involved in multiple cellulose-responsive signaling pathways in Aspergillus aculeatus. Reviewed

    Tsumura R, Sawada K, Kunitake E, Sumitani J, Kawaguchi T, Tani S*

    Applied Microbiology and Biotechnology 雑誌   2021.01

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    Kind of work:Joint Work  

  • Chemical genetic approach using β-rubromycin reveals that a RIO kinase-like protein is involved in morphological development in Phytophthora infestans. Reviewed

    Tani S*, Nishio N, Kai K, Hagiwara D, Ogata Y, Tojo M, Sumitani J, Judelson HS, Kawaguchi T.

    Scientific Reports 雑誌   2020.12

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    Kind of work:Joint Work  

  • Engineering of the Trichoderma reesei xylanase3 promoter for efficient enzyme expression Reviewed

    Hirasawa, H., Shioya, K., Furukawa, T., Tani, S., Sumitani, J.-I., Kawaguchi, T., Morikawa, Y., Shida, Y., Ogasawara, W.

    Applied Microbiology and Biotechnology 雑誌   102 ( 6 )   2737 - 2752   2018.03

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    Kind of work:Joint Work  

  • Dipeptidyl peptidase IV is involved in the cellulose-responsive induction of cellulose biomass-degrading enzyme genes in Aspergillus aculeatus Reviewed

    Tani, S., Yuki, S., Kunitake, E., Sumitani, J.-I., Kawaguchi, T.

    Bioscience, Biotechnology and Biochemistry 雑誌   81 ( 6 )   1227 - 1234   2017.06

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    Kind of work:Joint Work  

  • Site-saturation mutagenesis for β-glucosidase 1 from Aspergillus aculeatus to accelerate the saccharification of alkaline-pretreated bagasse. Reviewed

    Baba, Y., Sumitani, J.*, Tani, S., Kawaguchi, T.

    Appl. Microbiol. Biotechnol. 雑誌   100 ( 24 )   2016.12

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    Kind of work:Joint Work  

  • Heterologously expressed Aspergillus aculeatus β-glucosidase in Saccharomyces cerevisiae is a cost-effective alternative to commercial supplementation of β-glucosidase in industrial ethanol production using Trichoderma reesei cellulases. Reviewed

    Treebupachatsakul, T., Nakazawa, H., Shinbo, H., Fujikawa, H., Nagaiwa, A., Ochiai, N., Kawaguchi, T., Nikaido, M., Totani, K., Shioya, K., Shida, Y., Morikawa, Y., Ogasawara, W.*, and Okada, H.

    J. Biosci. Bioeng. 雑誌   121 ( 1 )   2016.01

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    Kind of work:Joint Work  

  • A high performance Trichoderma reesei strain that reveals the importance of xylanase III in cellulosic biomass conversion. Reviewed

    Nakazawa, H., Kawai, T., Ida, N., Shida, Y., Shioya, K., Kobayashi, Y., Okada, H., Tani, S., Sumitani, J.-I., Kawaguchi, T., Morikawa, Y., Ogasawara, W.

    Enz. Microb. Technol. 雑誌   82   2016.01

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    Kind of work:Joint Work  

  • Utilization of recombinant Trichoderma reesei expressing Aspergillus aculeatus β-glucosidase 1 (JN11) for a more economical production of ethanol from lignocellulosic biomass. Reviewed

    Treebupachatsakul, T., Shioya, K., Nakazawa, H., Kawaguchi, T., Morikawa, Y., Shida, Y., Ogasawara, W.*, and Okada, H.

    J. Biosci. Bioeng. 雑誌   120 ( 6 )   2015.12

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    Kind of work:Joint Work  

  • Characterization and gene cloning of a maltotriose-forming exo-amylase from Kitasatospora sp. MK-1785. Reviewed

    Kamon, M., Sumitani, J.*, Tani, S., and Kawaguchi, T.

    Appl. Microbiol. Biotechnol. 雑誌   99 ( 11 )   2015.06

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    Kind of work:Joint Work  

  • Effects of clbR overexpression on enzyme production in Aspergillus aculeatus vary depending on the cellulosic biomass-degrading enzyme species. Reviewed

    Kunitake, E., Kawamura, A, Tani, S.*, Takenaka, S., Ogasawara, W., Sumitani, J., and Kawaguchi, T.

    Biosci. Biotechnol. Biochem. 雑誌   79 ( 3 )   2015.03

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    Kind of work:Joint Work  

  • Effects of clbR overexpression on enzyme production in Aspergillus aculeatus vary depending on the cellulosic biomass-degrading enzyme species Reviewed

    Kunitake, E., Kawamura, A., Tani, S. Takenaka, S., Ogasawara, W., Sumitani, J.-I., Kawaguchi, T.

    Bioscience, Biotechnology and Biochemistry 雑誌   79 ( 3 )   488 - 495   2015.03

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    Kind of work:Joint Work  

  • Characterization of Aspergillus aculeatus β-glucosidase 1 accelerating cellulose hydrolysis with Trichoderma cellulase system. Reviewed

    Baba, Y., Sumitani, J.*, Tani, S., and Kawaguchi, T.

    AMB Express 雑誌   5 ( 1 )   2015.01

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    Kind of work:Joint Work  

  • Complex regulation of hydrolytic enzyme genes for cellulosic biomass degradation in filamentous fungi.

    Tani, S.*, Kawaguchi, T., and Kobayashi, T.

    Appl. Microbiol. Biotechnol. 雑誌   98 ( 11 )   2014.06

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    Kind of work:Joint Work  

  • Crystal structure of glycoside hydrolase family 3 beta-glucosidase 1 from Aspergillus aculeatus. Reviewed

    Suzuki, K., Sumitani, J., Nam, Y.-W., Nishimaki, T., Tani, S., Wakagi, T., Kawaguchi, T., and Fushinobu, S.

    Biochem. J. 雑誌   452 ( 2 )   2013.06

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    Kind of work:Joint Work  

  • A novel transcriptional regulator, ClbR, controls the cellobiose- and cellulose-responsive induction of cellulase and xylanase genes regulated by two distinct signaling pathways in Aspergillus aculeatus. Reviewed

    Kunitake, E., Tani, S.*, Sumitani, J.-I., and Kawaguchi, T.

    Appl. Microbiol. Biotechnol. 雑誌   97 ( 5 )   2013.03

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    Kind of work:Joint Work  

  • Reversible impairment of the ku80 gene by a recyclable marker in Aspergillus aculeatus. Reviewed

    Tani, S., Tsuji, A., Kunitake, E., Sumitani, J.-I., and Kawaguchi, T.

    AMB Express 雑誌   3 ( 1 )   2013.01

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    Kind of work:Joint Work  

  • A protein from Pleurotus eryngii var. tuoliensis C.J. Mou with strong removal activity against the natural steroid hormone, estriol: Purification, characterization, and identification as a laccase Reviewed

    Ueda, M. Shintani, K., Nakanishi-Anjyuin, A., Nakazawa, M., Kusuda, M., Nakatani, F., Kawaguchi, T., Tsujiyama, S.-I., Kawanishi, M., Yagi, T., Miyatake, K.

    Enzyme and Microbial Technology 雑誌   51 ( 6-7 )   402 - 407   2012.12

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    Kind of work:Joint Work  

  • Analysis of the saccharification capability of high-functional cellulase JN11 for various pretreated biomasses through a comparison with commercially available conterparts. Reviewed

    Kawai, T., Nakazawa, H., Iba, N., Okada, H., Tani, S., Sumitani, J.-I., Kawaguchi, T., Ogasaweara, W., Morikawa, Y., and Kobayashi, Y.

    Journal of Industrial Microbiology and Biotechnology 雑誌   39 ( 12 )   2012.09

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    Kind of work:Joint Work  

  • XlnR-independent signaling pathway regulates both cellulase and xylanase genes in response to cellobiose in Aspergillus aculeatus Reviewed

    Tani, S., Kanamasa, S., Sumitani, J., Arai, M., Kawaguchi, T.

    Current Genetics 雑誌   58 ( 2 )   93 - 104   2012.04

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    Kind of work:Joint Work  

  • Halophilic characterization of starch-binding domain from Kocuria varians α-amylase Reviewed

    Yamaguchi, R., Inoue, Y., Tokunaga, H., Ishibashi, M., Arakawa, T., Sumitani, J.-I., Kawaguchi, T., Tokunaga, M.

    International Journal of Biological Macromolecules 雑誌   50 ( 1 )   95 - 102   2012.01

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    Kind of work:Joint Work  

  • Construction of a recombinant Trichoderma reesei strain expressing Aspergillus aculeatus β-glucosidase 1 for efficient biomass conversion Reviewed

    Nakazawa, H., Kawai, T., Ida, N., Shida, Y., Kobayashi, Y., Okada, H., Tani, S., Sumitani, J.-I., Kawaguchi, T., Morikawa, Y., Ogasawara, W.

    Biotechnology and Bioengineering 雑誌   109 ( 1 )   92 - 99   2012.01

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    Kind of work:Joint Work  

  • Agrobacterium tumefaciens-mediated transformation of aspergillus aculeatus for insertional mutagenesis Reviewed

    Kunitake, E., Tani, S., Sumitani, J.-I., Kawaguchi, T.

    AMB Express 雑誌   1 ( 1 )   1 - 11   2011.01

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    Kind of work:Joint Work  

  • Improvement of Aspergillus oryzae for hyperproduction of endoglucanase: Expression cloning of cmc-1 gene of Aspergillus aculeatus Reviewed

    Rashid, M.H., Javed, M.R., Kawaguchi, T., Sumitani, J.-I., Arai, M

    Biotechnology Letters 雑誌   30 ( 12 )   2165 - 2172   2008.12

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    Kind of work:Joint Work  

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Presentations

  • 糸状菌 Aspergillus aculeatus における隔壁形成因子SepLの機能解析 Domestic conference

    菊矢 咲季、炭谷 順一、川口 剛司、谷 修治

    日本農芸化学会2023年度大会  2023.03  日本農芸化学会

  • 糸状菌糖質加水分解酵素遺伝子におけるエピメラーゼを介した選択的発現誘導機構の解明

    久我 瑞希、炭谷 順一、川口 剛司、谷 修治

    日本農芸化学会2023年度大会  2023.03  日本農芸化学会

  • パラジウム還元細菌 Citrobacter sp. no. 172株におけるペリプラズム電子輸送体の探索 Domestic conference

    江川 綾乃、藤田 沙保、谷 修治、川口 剛司、炭谷 順一

    日本農芸化学会2023年度大会  2023.03  日本農芸化学会

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    Presentation type:Oral presentation (general)  

  • 糸状菌Aspergillus aculeatus における酸化ストレス応答へ のdipeptidyl peptidase IV の寄与 Domestic conference

    森 孝輔, 炭谷 順一, 谷 修治, 川口 剛司

    日本生物工学会  2021.10 

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    Presentation type:Poster presentation  

  • Citrobacter sp. No.172株のPd(II)還元に関与する因子の探索 Domestic conference

    藤田沙保、谷修治、炭谷順一、川口剛司

    日本農芸化学会関西支部第516回講演会  2021.07 

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    Presentation type:Poster presentation  

  • 卵菌 Phytophthora infestans RIO kinase-like 遺伝子の機能解析 Domestic conference

    谷修治,西尾尚堯, 炭谷順一, Howard S. Judelson, 川口剛司

    第19回糸状菌分子生物学コンファレンス  2019.11 

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    Presentation type:Poster presentation  

  • SrpkF participates in the early phase of induction in response to cellulosic carbon sources in Aspergillus aculeatus International conference

    Natsumi Kobayashi, Ryosuke Katayama, Jun-ichi Sumitani, Shuji Tani, Takashi Kawaguchi

    Asian Mycology Congress 2019  2019.10 

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    Presentation type:Poster presentation  

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Industrial Property Rights

  • 新規β-アミラーゼ及びその利用・製造法

    炭谷順一,谷修治,川口剛司

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    property_type:Patent 

Outline of collaborative research (seeds)

  • 有用酵素の改良

  • 糸状菌の遺伝子発現制御機構

  • 微生物機能による物質変換

  • セルロース性バイオマスの有効利用

Charge of on-campus class subject

  • General Principles of Applied Biological Chemistry

    2021    

  • Topics in Applied Microbiology

    2021    

  • Introduction to Life, Environment, and Advanced Sciences

    2021    

  • Applied Microbiology

    2021    

  • Molecular Genetics

    2021    

Visiting Lectures ⇒ Link to the list of Visiting Lectures

  • くらしと微生物 ―小さな命の大きな働き―

    Category:Agricultural science (applied biology, biofunctional chemistry, green space environmental science)

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    Audience:Junior high school students, High school students, College students, General, Company

    微生物といえば,食品の腐敗,食中毒,病気,アレルギーなどといった悪い面が強調されがちですが,本当はこのような悪玉菌よりヒトの暮らしに役立つ善玉菌の方がはるかに多いのです.私たちの暮らしを豊かにしてくれている微生物の働きについて紹介します.