Updated on 2024/11/08

写真a

 
Kojima Hideo
 
Organization
Graduate School of Science Department of Chemistry Lecturer
School of Science Department of Chemistry
Title
Lecturer
Affiliation
Institute of Science
Contact information
メールアドレス
Affiliation campus
Sugimoto Campus

Position

  • Graduate School of Science Department of Chemistry 

    Lecturer  2022.04 - Now

  • School of Science Department of Chemistry 

    Lecturer  2022.04 - Now

Degree

  • Doctor of Engineering ( Others ) (   Osaka Prefecture University )

Research Areas

  • Nanotechnology/Materials / Synthetic organic chemistry

  • Nanotechnology/Materials / Bio chemistry  / Biocatalysis

  • Nanotechnology/Materials / Structural organic chemistry and physical organic chemistry  / Organic Synthesis

  • Life Science / Bioorganic chemistry  / Organic Synthesis

  • Nanotechnology/Materials / Green sustainable chemistry and environmental chemistry

Research Interests

  • Biocatalysis

  • Organic Synthesis

  • 合成化学

  • 有機化学

  • 生体触媒化学

  • Biocatalysis

  • Organic Chemistry

  • Synthetic Chemistry

Research subject summary

  • 生体触媒を用いる有機合成

  • 生理活性を有する化合物の合成

Research Career

  • Biotransformations in Organic Chemistry

    Individual

    2003.04 - Now 

  • 生理活性を有する化合物の合成

    Joint Research in Japan

    1992.04 - Now 

Professional Memberships

  • The Chemical Society of Japan

    1986.04 - Now   Domestic

  • American Chemical Society

    1992.04 - Now   Overseas

  • 生体触媒化学研究会

    2013.12 - Now   Domestic

  • Japanese Society for Chemical Biology

    2010.04 - Now   Domestic

  • The Japanese Society of Carbohydrate Research

    1994.04 - Now   Domestic

  • The Japanese Society of Applied Glycoscience

    1994.04 - Now   Domestic

  • The Society of Synthetic Organic Chemistry, Japan

    1986.04 - Now   Domestic

  • イオン液体研究会

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Committee Memberships (off-campus)

  • 幹事   生体触媒化学研究会  

    2009.04 - Now 

  • 代議員   日本化学会  

    2015.10 - Now 

  • 近畿支部幹事   日本化学会  

    2001.04 - 2002.03 

  • 近畿支部常任幹事   日本化学会  

    2000.04 - 2001.03 

  • 近畿支部幹事   日本化学会  

    1999.04 - 2000.03 

  • 豊田理研ワークショップ 運営委員   豊田理化学研究所  

    2023.09 

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Job Career (off-campus)

  • Osaka Metropolitan University   Graduate School of Science, Department of Chemistry

    2022.04 - Now

  • 大阪女子大学理学部環境理学科講師

    1999.04 - 2005.03

  • 大阪女子大学学芸学部基礎理学科講師

    1998.04 - 1999.03

  • 米国コーネル大学客員研究員(大阪府在外研究員)

    1997.09 - 1998.08

  • 大阪女子大学学芸学部基礎理学科助手

    1992.04 - 1998.03

Education

  • Osaka Prefecture University   Graduate School, Division of Engineering   Department of Applied Chemistry   The second semester of doctoral program   Graduated/Completed

    1988.04 - 1992.03

  • Osaka Prefecture University   Graduate School, Division of Engineering   Department of Applied Chemistry   The first semester of doctoral program   Graduated/Completed

    1986.04 - 1988.03

  • Osaka Prefecture University   Faculty of Engineering   Department of Chemistry   Bachelor's Course   Graduated/Completed

    1982.04 - 1986.03

Papers

  • Aquatic plants as whole-cell biocatalysts for preparing optically active β-hydroxy esters Reviewed

    Yuya Machi, Jina Yoshida, Hideo Kojima

    Results in Chemistry   8   101564   2024.05

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1016/j.rechem.2024.101564

  • Effect of organic solvents on asymmetric reduction of β-keto esters using cyanobacterium Synechocystis sp. PCC 6803 Reviewed

    Shusei Tanaka, Hideo Kojima, Satomi Takeda, Rio Yamanaka, Tetsuo Takemura

    Tetrahedron Letters   77   153249 - 153249   2021.08( ISSN:0040-4039

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.tetlet.2021.153249

  • Asymmetric visible-light photobiocatalytic reduction of β-keto esters utilizing the cofactor recycling system in Synechocystis sp. PCC 6803 Reviewed

    Shusei Tanaka, Hideo Kojima, Satomi Takeda, Rio Yamanaka, Tetsuo Takemura

    Tetrahedron Letters   61 ( 24 )   2020.06( ISSN:0040-4039 ( eISSN:1873-3581

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    Publishing type:Research paper (scientific journal)  

    © 2020 Elsevier Ltd The asymmetric reduction of β-keto esters employing a wild-type strain of cyanobacterium Synechocystis sp. PCC 6803 under illumination of red LED light at 25 °C for 24 h was evaluated. As a result, the corresponding (R)-β-hydroxy esters were obtained as major products. The R-selectivity was shown to increase for bulkier substrates. Moreover, it was also found that the R-selectivity increased with decreasing substrate concentrations. This can be explained by the assumption that the Km value of the R-selective reductase is smaller than that of the S-selective enzyme involved in the reaction. Additionally, it was demonstrated that the R-selective reductase required the light-dependent production of reduced nicotinamide adenine dinucleotide phosphate (NADPH) for effective reaction; however, the S-selective variant did not. Overall, cyanobacterium was employed as a sustainable photobiocatalyst proliferating under illumination of light, while utilizing inorganic salts and atmospheric carbon dioxide (CO2). Employing the whole-cell system allowed for the preparation of industrially-important chiral compounds, such as optically active β-hydroxy esters.

    DOI: 10.1016/j.tetlet.2020.151973

  • Lipase-Catalyzed tert-Butoxycarbonylation of Alcohols Using Boc2O Reviewed

    Naoki Kishi, Hideo Kojima

    ChemistrySelect   4 ( 33 )   9570 - 9572   2019.09( eISSN:2365-6549

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    Publishing type:Research paper (scientific journal)  

    © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Lipase-catalyzed tert-butoxycarbonylation of alcohols using di-tert-butyl dicarbonate (Boc2O) was developed. Aspergillus niger lipase, Burkholderia cepacia lipase, Pseudomonas fluorescens lipase, Candida rugosa lipase, and Candida antarctica lipase B were examined. The reaction of benzyl alcohol with Boc2O proceeded smoothly in the presence of Candida rugosa lipase in hexane to produce benzyl tert-butyl carbonate in a good yield. Similarly, the tert-butoxycarbonylation reactions of 4-methylbenzyl alcohol, 4-methoxybenzyl alcohol, 4-chlorobenzyl alcohol, 4-bromobenzyl alcohol, 4-nitrobenzyl alcohol, 2-phenylethanol, 3-phenyl-1-propanol, cinnamyl alcohol, and 2-naphthalene methanol using Boc2O in the presence of Candida rugosa lipase in hexane resulted in very good to-excellent yields of the corresponding tert-butoxycarbonylated alcohols.

    DOI: 10.1002/slct.201902423

  • Asymmetric reduction of fluorine-containing ketones using Synechocystis sp. PCC 6803

    Kazuma Ujigawa, Yuta Otani, Hideo Kojima, Satomi Takeda, Rio Yamanaka, Kaoru Nakamura

    Active Enzyme Molecule 2014   2014.12

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    Kind of work:Joint Work  

  • RARE EARTH TRIFLATES/CHLOROTRIMETHYLSILANE-PROMOTED ONE-POT SYNTHESIS OF ENALS Reviewed

    Natsuko Kagawa, Yoshiko Sasaki, Shoko Sakaguchi, Ayumi Nagatomo, Hideo Kojima, Masahiro Toyota

    HETEROCYCLES 雑誌   88 ( 2 )   1581 - 1585   2014.01

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    Kind of work:Joint Work  

  • Arabidopsis thaliana: a novel biocatalyst for asymmetric reductions Reviewed

    S. Takeda; Y. Ogata; H. Kojima; A. Okada; Y. Uranishi; K. Nakamura

    Plant Biotechnology Japanese Society of Plant Cell and Molecular Biology   28   77 - 82   2011.03

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    Kind of work:Joint Work  

  • Rare earth triflates/chlorotrimethylsilane indicated activation of triethylamine as a latent acetaldehyde anion: a new synthesis of α,β-unsaturated aldehydes Reviewed

    N. Kagawa, Y. Sasaki, H. Kojima, M. Toyota

    Tetrahedron Letters 雑誌 Elsevier   51 ( 3 )   482 - 484   2010.01

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    Kind of work:Joint Work  

  • Asymmetric reduction of ketones by cultured cells of Nicotiana tabacum

     

    12th Japanese Symposium on the Chemistry of Biocatalysis (Journal of Molecular Catalysis B: Enzymatic), Abstract Elsevier   62   108 - 126   2010

  • Effect of carbon dioxide concentrations on asymmetric reduction of ketones with plant cultured cells Reviewed

    H. Kojima, A. Okada, S. Takeda, K. Nakamura

    Tetrahedron Letters 雑誌 Elsevier   50 ( 50 )   7079 - 7081   2009.12

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    Kind of work:Joint Work  

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Presentations

  • Synthesis of 4-substituted-gentianines from swertiamarin Domestic conference

    Sakurako Shimizu, Ryoya Kaneko, Yuya Machi, Takaya Noguchi, Hideo Kojima, Yasuyuki Hirai, Mikio Fujii

    The 24th Biocatalysis Symposium of Japan   2024.10  The society of biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Gifu  

  • One-pot lipase-catalyzed aldol reaction in deep eutectic solvents Domestic conference

    Taito Nagamoto, Yuto Yamamoto, Hiroki Onishi, Hideo Kojima

    The 24th Biocatalysis Symposium of Japan   2024.10  The society of biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Gifu  

  • Additive effects on asymmetric reduction of fluorine-containing ketones using cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    Satsuki Fukui, Remi Nishimura, Hideo Kojima, Satomi Takeda, Rio Yamanaka

    The 24th Biocatalysis Symposium of Japan   2024.10  The society of biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Gifu  

  • Considerations for the lipase-catalyzed synthesis of Erlenmeyer azlactones Domestic conference

    Remi Nishimura, Hiroki Onishi, Satsuki Fukui, Hideo Kojima

    The 24th Biocatalysis Symposium of Japan   2024.10  The society of biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Gifu  

  • Synthesis and evaluation of the radical-scavenging activity of galloylated compounds Domestic conference

    Yuto Yamamoto, Kyoka Matsuhara, Chihaya Hase, Hideo Kojima, Yoshimi Shoji, Ikuo Nakanishi

    The 24th Biocatalysis Symposium of Japan   2024.10  The society of biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Gifu  

  • Synthesis of optically active β-hydroxy esters using Pisum sativum Domestic conference

    Ryota Shimamoto, Yuya Machi, Hideo Kojima, Satomi Takeda

    The 24th Biocatalysis Symposium of Japan   2024.10  The society of biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Gifu  

  • Asymmetric reduction of keto esters using Pisum sativum as a whole-cell biocatalyst Domestic conference

    Ryota Shimamoto, Yuya Machi, Hideo Kojima, Satomi Takeda

    The 104th CSJ Annual Meeting (2024)  2024.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Nihon University  

  • Biotransformation of cyclohexane to -caprolactone using Arabidopsis thaliana as a whole-cell biocatalyst Domestic conference

    Yuya machi, Jina Yoshida, Hideo Kojima, Satomi Takeda

    The 104th CSJ Annual Meeting (2024)  2024.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Nihon University  

  • Lipase-catalyzed alkoxycarbonylation in the deep eutectic solvent/water system Domestic conference

    Taito Nagamoto, Yuto Yamamoto, Hideo Kojima

    The 104th CSJ Annual Meeting (2024)  2024.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Nihon University  

  • Lipase-catalyzed alkoxycarbonylation in the presence of a solid acid catalyst Domestic conference

    Yuto Yamamoto, Hideo Kojima

    The 104th CSJ Annual Meeting (2024)  2024.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Nihon University  

  • The effect of sorbitol addition on the asymmetric reduction of ketones using cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    Satsuki Fukui, Hideo Kojima, Satomi Takeda, Rio Yamanaka

    The 104th CSJ Annual Meeting (2024)  2024.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Nihon University  

  • Lipase-catalyzed allyloxycarbonylation of alcohols using allyl phenyl carbonate Domestic conference

    Yuto Yamamoto, Hideo Kojima

    The 23rd Japanese Symposium on the Chemistry of Biocatalysis (2023)  2023.09  The Society of Biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Kagoshima University  

  • Tannase-catalyzed galloylation of alcohols in the mixed solvent system of hexane/tert-butanol Domestic conference

    Renshiro Otaka, Hideo Kojima

    The 23rd Japanese Symposium on the Chemistry of Biocatalysis (2023)  2023.09  The Society of Biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Kagoshima University  

  • Asymmetric reduction of ketones using Pisum sativum seedlings as whole-cell biocatalysts Domestic conference

    Ryota Shimamoto, Yuya Machi, Hideo Kojima, Satomi Takeda

    The 23rd Japanese Symposium on the Chemistry of Biocatalysis (2023)  2023.09  The Society of Biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Kagoshima University  

  • Lipase-catalyzed benzyloxycarbonylation of alcohols in the deep eutectic solvent system of choline chloride/urea Domestic conference

    Taito Nagamoto, Yuto Yamamoto, Hideo Kojima

    The 23rd Japanese Symposium on the Chemistry of Biocatalysis (2023)  2023.09  The Society of Biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Kagoshima University  

  • Additive effects on asymmetric reduction of ketones using cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    Satsuki Fukui, Hideo Kojima, Satomi Takeda, Rio Yamanaka

    The 23rd Japanese Symposium on the Chemistry of Biocatalysis (2023)  2023.09  The Society of Biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Kagoshima University  

  • Asymmetric reduction of ketones using aquatic plants as whole-cell biocatalyst Domestic conference

    Yuya Machi, Hideo Kojima

    The 23rd Japanese Symposium on the Chemistry of Biocatalysis (2023)  2023.09  The Society of Biocatalysis Japan

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    Presentation type:Poster presentation  

    Venue:Kagoshima University  

  • Effect of additive concentration on asymmetric reduction of fluorine-containing ketones using cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    Satsuki Fukui, Jina Yoshida, Hideo Kojima, Satomi Takeda, Rio Yamanaka

    The 103rd CSJ Annual Meeting  2023.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Tokyo University of Science  

  • Lipase-catalyzed benzyloxycarbonylation of alcohols Domestic conference

    Yuto Yamamoto, Yuki Hatayama, Hideo Kojima

    The 103rd CSJ Annual Meeting  2023.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Tokyo University of Science  

  • Galloylation of alcohols using immobilized Aspergillus oryzae tannase in organic media Domestic conference

    Renshiro Otaka, Yuki Hatayama, Hideo Kojima

    The 103rd CSJ Annual Meeting  2023.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

    Venue:Tokyo University of Science  

  • 炭酸ベンジルフェニルを用いるリパーゼ触媒ベンジルオキシカルボニル化 Domestic conference

    山本悠人、畑山友希、小島秀夫

    第1回学際化学若手育成シンポジウム  2023.03  大阪公立大学大学院理学研究科化学専攻

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    Presentation type:Poster presentation  

    Venue:大阪公立大学 杉本キャンパス  

  • Lipase-catalyzed alkoxycarbonylation of alcohols using alkyl aryl carbonates International conference

    Yuki Hatayama, Yuto Yamamoto, Hideo Kojima

    Active Enzyme Molecule 2022  2022.10  Toyama Pharmaceutical Valley Development Consortium

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    Presentation type:Poster presentation  

    Venue:Toyama Prefectural University, Imizu, Japan  

  • Asymmetric reduction of ketones using aquatic plants as whole-cell biocatalysts International conference

    Jina Yoshida, Maya Saito, Hideo Kojima

    Active Enzyme Molecule 2022  2022.10  Toyama Pharmaceutical Valley Development Consortium

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    Presentation type:Poster presentation  

    Venue:Toyama Prefectural University, Imizu, Japan  

  • Tannase-catalyzed galloylation of alcohols in organic solvents International conference

    Renshiro Otaka, Yuki Hatayama, Hideo Kojima

    Active Enzyme Molecule 2022  2022.09  Toyama Pharmaceutical Valley Development Consortium

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    Presentation type:Poster presentation  

    Venue:Toyama Prefectural University, Imizu, Japan  

  • Asymmetric reduction of fluorine-containing ketones using cyanobacterium Synechocystis sp. PCC 6803 International conference

    Satsuki Fukui, Itsuku Makigawa, Jina Yoshida, Hideo Kojima, Satomi Takeda, Rio Yamanaka

    Active Enzyme Molecule 2022  2022.09  Toyama Pharmaceutical Valley Development Consortium

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    Presentation type:Poster presentation  

    Venue:Toyama Prefectural University, Imizu, Japan  

  • Control of the Enantioselectivity on Asymmetric Reduction of Fluorine-containing Ketones Using Cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    Itsuku Makigawa, Satsuki Fukui, Hideo Kojima, Satomi Takeda, Rio Yamanaka

    The 102nd CSJ Annual Meeting  2022.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

  • Reduction of α-keto esters using Pisum sativum sprouts Domestic conference

    Ko Azuma, Hideo Kojima

    The 102nd CSJ Annual Meeting  2022.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

  • Immobilizing agents of tannase effective for galloylation of alcohols Domestic conference

    Renshiro Otaka, Yuki Hatayama, Hideo Kojima

    The 102nd CSJ Annual Meeting  2022.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

  • Lipase-catalyzed alkoxycarbonylation of alcohols Domestic conference

    Yuki Hatayama, Yuto Yamamoto, Hideo Kojima

    The 102nd CSJ Annual Meeting  2022.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

  • Asymmetric reduction of ketones using aquatic plant Cabomba caroliniana Domestic conference

    Jina Yoshida, Maya Saito, Hideo Kojima

    The 102nd CSJ Annual Meeting  2022.03  The Chemical Society of Japan

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    Presentation type:Poster presentation  

  • Asymmetric Reduction of Ketones Using Pisum Sativum Sprouts Domestic conference

    Ko Azuma, Hideo Kojima

    第101回春季年会  2021.03  日本化学会

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    Presentation type:Poster presentation  

  • Lipase-Catalyzed tert-Butoxycarbonylation of Alcohols Domestic conference

    Naoki Kishi, Hideo Kojima

    第101回春季年会  2021.03  日本化学会

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    Presentation type:Poster presentation  

  • Tannase-Catalyzed Galloylation of Diols Domestic conference

    Yuki Hatayama, Naoki Kishi, Hideo Kojima

    第101回春季年会  2021.03  日本化学会

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    Presentation type:Poster presentation  

  • Asymmetric Reduction of Ketones Using Cabomba Caroliniana Domestic conference

    ina Yoshida, Takuma Tsuji, Hideo Kojima

    第101回春季年会  2021.03  日本化学会

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    Presentation type:Poster presentation  

  • Effect of Organic Solvents on Asymmetric Reduction of β-Keto Esters Using Cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    Shusei Tanaka, Hideo Kojima, Satomi Takeda, Rio Yamanaka, Tetsuo Takemura, Kaoru Nakamura

    第22回生体触媒化学シンポジウム  2020.12 

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  • Lipase Catalyzed tert-Butoxycarbonylation of Diols Domestic conference

    the 100th CSJ Annual Meeting  2020.03 

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  • Lipase Catalyzed Silylation of Alcohols Domestic conference

    the 100th CSJ Annual Meeting  2020.03 

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    Presentation type:Poster presentation  

  • Asymmetric Reduction of Ketones Using Submerged Aquatic Plants of the Family Potamogetonance Domestic conference

    the 100th CSJ Annual Meeting  2020.03 

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    Presentation type:Poster presentation  

  • Asymmetric Reduction of Benzoylformic Acid Esters Using Cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    the 100th CSJ Annual Meeting  2020.03 

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  • Synthesis and Evaluation of Radical Scavenging Activity of Gallotannins Domestic conference

    岸 直輝, 小島秀夫, 中西郁夫

    第21回生体触媒化学シンポジウム  2019.08  生体触媒化学研究会

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  • Asymmetric Reduction of Ketones Using Cyanobacterium Synechocystis sp. PCC 6803 Domestic conference

    田中秀成,小島秀夫,竹田恵美,山中理央,竹村哲雄,中村 薫

    第21回生体触媒化学シンポジウム  2019.08  生体触媒化学研究会

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  • Biotransformation Using Arabidopsis thaliana Domestic conference

    辻 拓馬, 小島 秀夫, 竹田 恵美

    第21回生体触媒化学シンポジウム  2019.08  生体触媒化学研究会

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    Presentation type:Poster presentation  

  • Biotransformation Using Aquatic Plants Domestic conference

    Tsuji, T.; Azuma, K.; Kojima

    the 99th CSJ Annual Meeting   2019.03 

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    Presentation type:Poster presentation  

  • Effect of Light on Asymmetric Reduction of Ketones Using Cyanobacterium Synechocystis sp. PCC6803 Domestic conference

    Tanaka, S.; Kojima, H.; Takeda, S.; Yamanaka, R.; Takemura, T.; Nakamura, K.

    the 99th CSJ Annual Meeting  2019.03 

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  • Lipase-Catalyzed tert-Butoxycarbonylation of Alcohols Domestic conference

    Kishi, N.; Kojima, H.

    the 99th CSJ Annual Meeting  2019.03 

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  • Synthesis of shikimic acid derivatives using Arabidopsis thaliana Domestic conference

    Takuma Tsuji, Hideo Kojima, Satomi Takeda

    第20回生体触媒化学シンポジウム  2018.12  生体触媒化学研究会

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  • Effect of light on asymmetric reduction of ketones using cyanobacteria Domestic conference

    Shusei Tanaka, Hideo Kojima, Satomi Takeda, Rio Yamanaka, Tetsuo Takemura, Kaoru Nakamura

    第20回生体触媒化学シンポジウム  2018.12  生体触媒化学研究会

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  • Lipase-catalyzed tert-butoxycarbonylation using Boc2O Domestic conference

    Naoki Kishi and Hideo Kojima

    第20回生体触媒化学シンポジウム  2018.12  生体触媒化学研究会

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  • Synthesis of shikimic acid using an Arabidopsis thaliana seedling as a biocatalyst Domestic conference

    Hideo Kojima, Ayaka Inui, Satomi Takeda

    2018.03 

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  • シロイヌナズナ植物細胞を用いるケトンの不斉還元 Domestic conference

    大久保史都、吉原静恵、小島秀夫

    第19回生体触媒化学シンポジウム  2017.12  生体触媒化学研究会

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  • 3,4-ジガロイル-1,5-キノラクトン及び関連化合物の合成と 膵リパーゼ阻害活性の評価 Domestic conference

    森実仁晃,関根(鈴木)絵美子,上野恵美,中西郁夫,小島秀夫

    第19回生体触媒化学シンポジウム  2017.12  生体触媒化学研究会

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  • シアノバクテリアSynechocystis sp. PCC 6803を用いる ケトンの不斉還元 Domestic conference

    中村有希,田中秀成,勝原拓也,小島秀夫,竹田恵美,山中理央, 竹村哲雄,中村 薫

    第19回生体触媒化学シンポジウム  2017.12  生体触媒化学研究会

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  • Pancreatic Lipase Inhibitory Activity of Quinic Acid Derivatives Domestic conference

    MORIZANE Masaaki, KITAGAWA Kai, NISHIDA Kotaro, KOJIMA Hideo

    2017.03 

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    Presentation type:Oral presentation (invited, special)  

  • リパーゼ触媒不斉アシル化に利用可能な固定化アシルドナーの合成 Domestic conference

    杉本 真規,小島 秀夫

    第18回生体触媒化学シンポジウム  2016.12  生体触媒化学研究会

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  • シアノバクテリアを用いたケトンの不斉還元 Domestic conference

    勝原拓也,大久保史都,小島秀夫,竹田恵美,山中理央,中村 薫

    第18回生体触媒化学シンポジウム  2016.12  生体触媒化学研究会

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  • シロイヌナズナを生体触媒として用いるシキミ酸誘導体の合成 Domestic conference

    佐賀 亜香里,乾 彩香,大久保 史都,竹田 恵美,小島 秀夫

    第18回生体触媒化学シンポジウム  2016.12  生体触媒化学研究会

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  • 膵リパーゼ阻害活性を有するキノラクトン類の合成 Domestic conference

    森実仁晃,小島秀夫

    第18回生体触媒化学シンポジウム  2016.12  生体触媒化学研究会

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  • Hemianthus callitrichoidesを用いたケトンの不斉還元における 蛍光フィルムの効果 Domestic conference

    大久保史都,前田壮志,小島秀夫

    第18回生体触媒化学シンポジウム  2016.12  生体触媒化学研究会

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  • Synthesis of Quinic Acid Derivatives with Pancreatic Lipase Inhibitory Activity Domestic conference

    2016.03 

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    Presentation type:Poster presentation  

  • Enzymatic Galloylation of Alcohols using Immobilized Tannase Domestic conference

    2016.03 

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    Presentation type:Poster presentation  

  • Preparation of Optically Active Alcohols using Submerged Aquatic Plants as Biocatalysts Domestic conference

    2016.03 

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  • Lipase Catalyzed Acylation using Solid Acyl Donors Domestic conference

    2016.03 

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    Presentation type:Poster presentation  

  • リパーゼを用いたα-ヒドロキシエステル類の動的速度論的光学分割 Domestic conference

    杉本 真規・佐藤 正明・小島 秀夫

    第95春季年会  2015.03  日本化学会

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  • 水生植物を用いたケトンの不斉還元 Domestic conference

    大久保 史都、宇治川 数馬、小島 秀夫

    第95春季年会  2015.03  日本化学会

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  • 固定化タンナーゼを用いた没食子酸エステルの不斉加水分解 Domestic conference

    森実 仁晃・西田 耕太朗・小島 秀夫

    第95春季年会  2015.03  日本化学会

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  • Asymmetric reduction of fluorine-containing ketones using Synechocystis sp. PCC 6803 International conference

    Kazuma Ujigawa, Yuta Otani, Hideo Kojima, Satomi Takeda, Rio Yamanaka and Kaoru Nakamura

    Active Enzyme Molecule 2014  2014.12 

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  • ガロタンニン類のラット胸腺細胞に対する放射線防護活性 Domestic conference

    西田耕太朗・関根(鈴木)絵美子・中西郁夫・上野恵美・ 松本謙一郎・村上 健・小島秀夫

    第67回日本酸化ストレス学会学術集会  2014.09  日本酸化ストレス学会

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  • 沈水性水生植物を用いた物質変換 Domestic conference

    宇治川 数馬、大野 恵、大谷 優太、小島 秀夫

    第94春季年会  2014.03  日本化学会

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  • 膵リパーゼ阻害活性をもつガロタンニン類の合成 Domestic conference

    西田 耕太朗、井隼 浩太、宇治川 数馬、小島 秀夫

    第94春季年会  2014.03  日本化学会

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  • テオガリン類の合成と膵リパーゼ阻害活性の評価 Domestic conference

    井隼浩太,西田耕太朗,小島秀夫

    第17回生体触媒化学シンポジウム  2013.12  生体触媒化学研究会

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  • カヤツリグサ科の水生植物を用いたケトンの不斉還元 Domestic conference

    大野 恵,宇治川数馬,小島秀夫

    第17回生体触媒化学シンポジウム  2013.12  生体触媒化学研究会

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  • シロイヌナズナの酸化還元酵素遺伝子破壊株を用いたケトンの不斉還元 Domestic conference

    宇治川数馬,小島秀夫,和田 優,竹田恵美,中村 薫

    第17回生体触媒化学シンポジウム  2013.12  生体触媒化学研究会

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  • ガロタンニン類の合成とフリーラジカル消去反応における構造活性相関 Domestic conference

    井隼浩太、中西郁夫、大久保 敬、福住俊一、小島秀夫

    第66回日本酸化ストレス学会学術集会  2013.06  日本酸化ストレス学会

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  • ガロタンニン類の合成とそのラジカル消去活性 Domestic conference

    井隼浩太・西田耕太朗・中西郁夫・小島秀夫

    第93春季年会  2013.03  日本化学会

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  • 沈水性水生植物を生体触媒として用いるケトンの不斉還元 Domestic conference

    宇治川数馬・大野 恵・小島秀夫

    第93春季年会  2013.03  日本化学会

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  • 固定化リパーゼ/酸性樹脂触媒を用いるアルコールの連続フロー系動的速度論的光学分割 Domestic conference

    松本洋平、佐藤正明、小島秀夫

    第16回生体触媒化学シンポジウム  2012.11  生体触媒化学研究会

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  • シロイヌナズナ変異株を用いたケトンの不斉還元 Domestic conference

    宇治川数馬、小島秀夫、和田優、竹田恵美、中村薫

    第16回生体触媒化学シンポジウム  2012.11  生体触媒化学研究会

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  • 膵リパーゼ阻害活性を有するテオガリン誘導体の合成 Domestic conference

    井隼浩太、宇佐良輔、小島秀夫

    第92春季年会  2012.03  日本化学会

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  • フロー系におけるリパーゼを用いた動的速度論的光学分割 Domestic conference

    松本洋平、佐藤正明、小島秀夫

    第92春季年会  2012.03  日本化学会

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  • 芳香族ヒドロキシ酸グルコシルエステル類の合成 Domestic conference

    宇佐良輔・井隼浩太・小島秀夫

    第15回生体触媒化学シンポジウム  2011.12  生体触媒化学研究会

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  • フロー系におけるリパーゼを用いたアルコールの動的速度論的光学分割 Domestic conference

    松本洋平・浦西洋輔・佐藤正明・小島秀夫

    第15回生体触媒化学シンポジウム  2011.12  生体触媒化学研究会

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  • シロイヌナズナ芽生えを生体触媒として用いた不斉反応系の開発 Domestic conference

    竹田恵美・岡田亜希子・尾形有香・小島秀夫・中村 薫

    第29回日本植物細胞分子生物学会大会・シンポジウム  2011.09  日本植物細胞分子生物学会

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  • 芳香族ヒドロキシ酸グルコシルエステル類の化学酵素的合成 Domestic conference

    宇佐良輔,井隼浩太,小島秀夫

    第91春季年会  2011.03  日本化学会

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  • フロー系における固定化リパーゼを用いたアルコールの動的速度論的光学分割 Domestic conference

    浦西洋輔,佐藤正明,小島秀夫

    第91春季年会  2011.03  日本化学会

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  • 1-O-ヒドロキシシンナモイル-β-D-グルコース類の化学酵素的合成 Domestic conference

    宇佐良輔,小島秀夫

    第14回生体触媒化学シンポジウム  2010.09  生体触媒化学研究会

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  • シロイヌナズナ芽生えを生体触媒として用いたケトン類の不斉還元 Domestic conference

    竹田恵美, 尾形有香, 小島秀夫, 岡田亜希子, 中村 薫

    第51回日本植物生理学会年会  2010.03  日本植物生理学会

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  • リパーゼを用いるシナポイルグルコシドの合成 Domestic conference

    宇佐良輔,小島秀夫

    第90春季年会  2010.03  日本化学会

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  • リパーゼを用いたヒドロキシケイ皮酸グルコシルエステル類の合成 Domestic conference

    小島秀夫,宇佐良輔,中村 薫

    第13回生体触媒化学シンポジウム  2009.12  生体触媒化学研究会

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  • タバコ培養細胞を用いたケトン類の不斉還元 Domestic conference

    岡田亜季子,小島秀夫,竹田恵美,中村 薫

    第12回生体触媒化学シンポジウム  2008.12  生体触媒化学研究会

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  • タバコ培養細胞を用いたケトン類の不斉還元 Domestic conference

    岡田亜季子,小島秀夫,竹田恵美,中村 薫

    第88春季年会  2008.03  日本化学会

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  • リパーゼを用いたモノグルコサミニルジグリセリドの合成 Domestic conference

    小島秀夫,佐伯めぐみ,中村 薫

    第88春季年会  2008.03  日本化学会

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  • タバコ培養細胞を用いたケトン類の不斉還元 Domestic conference

    岡田亜季子,小島秀夫,竹田恵美,中村 薫

    第11回生体触媒化学シンポジウム  2008.01  生体触媒化学研究会

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  • リパーゼを用いた酢酸エステルの選択的加水分解 Domestic conference

    小島秀夫,山口南美,大森愛子,中村 薫

    第11回生体触媒化学シンポジウム  2008.01  生体触媒化学研究会

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  • リパーゼを用いたモノグルコサミニルジグリセリドの合成 Domestic conference

    小島秀夫,佐伯めぐみ,中村 薫

    第11回生体触媒化学シンポジウム  2008.01  生体触媒化学研究会

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  • リパーゼを用いた光学活性meso-2,3-ブタンジオールエステルの合成 Domestic conference

    小島秀夫,岡本明弥,中村 薫

    第11回生体触媒化学シンポジウム  2008.01  生体触媒化学研究会

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  • ランタノイド金属を用いる触媒的オレフィン化反応の新機軸 Domestic conference

    佐々木美子,加川夏子,小島秀夫,豊田真弘

    第33回反応と合成の進歩シンポジウム  2007.11  日本薬学会化学系薬学部会

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  • タバコ培養細胞を用いるケトン類の不斉還元 Domestic conference

    岡田亜季子,小島秀夫,竹田恵美,中村 薫

    第87春季年会  2007.03  日本化学会

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  • ハトムギ由来コイクセノリドの合成 Domestic conference

    木本梨絵,小島秀夫,中村 薫

    第87春季年会  2007.03  日本化学会

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  • シロイヌナズナ及びタバコ培養細胞によるケトン類の不斉還元 Domestic conference

    岡田亜季子,小島秀夫,竹田恵美,中村 薫

    第10回生体触媒化学シンポジウム  2006.12  生体触媒化学研究会

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  • 酵素的グルコシル化による生理活性物質の合成 Domestic conference

    大森愛子,小島秀夫,中村 薫

    第10回生体触媒化学シンポジウム  2006.12  生体触媒化学研究会

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  • ジオール類のリパーゼ触媒モノアシル化 Domestic conference

    木本梨絵,小島秀夫,中村 薫

    第10回生体触媒化学シンポジウム  2006.12  生体触媒化学研究会

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  • キラルイオン液体中でのプロリン触媒不斉アルドール反応 International conference

    小島秀夫,中村 薫

    International Molecular Chirality Conference 2006  2006.05  MCRO (Molecular Chirality Research Organization)

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  • 1-エトキシシクロプロピルをアシル化剤として用いるリパーゼ触媒反応 Domestic conference

    小島秀夫,山本弓,中村 薫

    第86春季年会  2006.03  日本化学会

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  • Synthesis of highly strained cyclopropyl esters and their application to lipase-catalyzed enantioselective acylation International conference

    HideoKojima,Chisato Sawano,Kaoru Nakamura

    2005環太平洋国際会議PACIFICHEM2005  2005.12 

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  • 高歪みをもつ酢酸1-エトキシシクロプロピルの合成とリパーゼ触媒不斉アシル化反応への応用 Domestic conference

    澤野千里,大島里紗,小島秀夫

    第85春季年会  2005.03  日本化学会

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  • 両親媒性イオン性液体-水系におけるランタノイドトリフラート触媒アルドール反応 Domestic conference

    大森愛子,岡本佳子,小島秀夫

    第85春季年会  2005.03  日本化学会

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  • キラルイオン性液体中第二級アミンを触媒とする不斉Diels-Alder反応 Domestic conference

    岡本佳子,大森愛子,小島秀夫

    第85春季年会  2005.03  日本化学会

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  • The Baker's Yeast Reduction of β-Keto Esters in the Presence of a Thioglycoside Domestic conference

    2004.12 

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  • 糖から誘導した両親媒性キラル配位子をもつランタノイド錯体の調製 Domestic conference

    岡本佳子,小島秀夫

    第84春季年会  2004.03  日本化学会

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  • チオグリコシド存在下におけるケトエステル類のパン酵母還元 Domestic conference

    澤野千里,小島秀夫

    第84春季年会  2004.03  日本化学会

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  • 光学活性スルホン酸類をアニオン前駆体とするキラルイオン性液体の合成 Domestic conference

    倉床弘美,小島秀夫

    第84春季年会  2004.03  日本化学会

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  • Synthesis of Oligosaccharides by Sequential Glycosylation Using Thiocellobiosides Domestic conference

    2003.03 

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  • Molecular Dynamics Simulation of Aqueous Solution of Trehalose Derivatives with Alkyl Chains Domestic conference

    2003.03 

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  • Synthesis of Oligosaccharides Using Thiocellobiosides Domestic conference

    2002.09 

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  • Synthesis of Thiol-Bearing Trehalose-Based Surfactants Domestic conference

    2002.03 

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  • Synthesis of Thiol-Bearing Glucose-Based Surfactants Domestic conference

    2001.03 

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  • Preparation of sulfur-containing trehaloselipids International conference

    Hideo Kojima,Saya Nishio,Saki Hanai,Miho Yokoji

    2000環太平洋国際会議PACIFICHEM2000  2000.12 

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  • Synthesis of Sulfur-Containing Trehalose Lipids Domestic conference

    2000.03 

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Outline of collaborative research (seeds)

  • Biotransformation in Organic Chemistry

Charge of on-campus class subject

  • 化学実験1

    2024   Weekly class   Undergraduate

  • 化学特別演習2A

    2024   Intensive lecture   Graduate school

  • 化学特別演習1A

    2024   Intensive lecture   Graduate school

  • 化学特別研究2A

    2024   Intensive lecture   Graduate school

  • 化学特別研究1A

    2024   Intensive lecture   Graduate school

  • 研究企画ゼミナール

    2024   Intensive lecture   Graduate school

  • 化学特別演習5A

    2024   Intensive lecture   Graduate school

  • 化学特別演習4A

    2024   Intensive lecture   Graduate school

  • 化学特別演習3A

    2024   Intensive lecture   Graduate school

  • 化学特別研究5A

    2024   Intensive lecture   Graduate school

  • 化学特別研究4A

    2024   Intensive lecture   Graduate school

  • 化学特別研究3A

    2024   Intensive lecture   Graduate school

  • 基礎化学実験

    2024   Weekly class   Graduate school

  • 化学実験Ⅱ

    2024   Weekly class   Undergraduate

  • 化学実験Ⅰ

    2024   Weekly class   Undergraduate

  • 海外特別研究4

    2023   Intensive lecture   Graduate school

  • 海外特別研究3

    2023   Intensive lecture   Graduate school

  • 化学特別演習4A

    2023   Intensive lecture   Graduate school

  • 化学特別演習3A

    2023   Intensive lecture   Graduate school

  • 化学特別研究4A

    2023   Intensive lecture   Graduate school

  • 化学特別研究3A

    2023   Intensive lecture   Graduate school

  • プロポーザルディフェンス

    2023   Intensive lecture   Graduate school

  • 海外特別研究2

    2023   Intensive lecture   Graduate school

  • 海外特別研究1

    2023   Intensive lecture   Graduate school

  • 化学特別演習2A

    2023   Intensive lecture   Graduate school

  • 化学特別演習1A

    2023   Intensive lecture   Graduate school

  • 化学特別研究2A

    2023   Intensive lecture   Graduate school

  • 化学特別研究1A

    2023   Intensive lecture   Graduate school

  • 研究企画ゼミナール

    2023   Intensive lecture   Graduate school

  • 分子科学実験II

    2023   Weekly class   Undergraduate

  • 有機化学演習I

    2023   Weekly class   Undergraduate

  • 基礎化学実験

    2023   Weekly class   Graduate school

  • 基礎化学実験

    2023   Weekly class   Graduate school

  • 機能分子化学特論A

    2023   Weekly class   Graduate school

  • 化学特別演習2B

    2023   Intensive lecture   Graduate school

  • 化学特別演習1B

    2023   Intensive lecture   Graduate school

  • 化学特別研究2B

    2023   Intensive lecture   Graduate school

  • 化学特別研究1B

    2023   Intensive lecture   Graduate school

  • 有機生物化学

    2023   Weekly class   Undergraduate

  • 分子科学実験I

    2023   Weekly class   Undergraduate

  • 化学特別演習4B

    2023   Intensive lecture   Graduate school

  • 化学特別演習3B

    2023   Intensive lecture   Graduate school

  • 化学特別研究4B

    2023   Intensive lecture   Graduate school

  • 化学特別研究3B

    2023   Intensive lecture   Graduate school

  • 化学特別演習1A

    2022   Intensive lecture   Graduate school

  • Chemistry Laboratory I

    2021   Practical Training  

  • Bioorganic Chemistry

    2021    

  • Fundamental Organic Biochemistry

    2021    

  • Exercises in Organic Chemistry I

    2021    

  • Laboratory Chemistry

    2021   Practical Training  

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Social Activities ⇒ Link to the list of Social Activities

  • 兵庫県立尼崎小田高等学校「大阪公立大学研修」

    Role(s): Lecturer, Performer

    大阪公立大学  2022.12

  • 高大連携事業「大学訪問研修」 分子における左と右

    2017.04 - 2018.03

  • 高大連携講座 植物を活用した環境に優しいものづくり

    2015.04 - 2016.03

  • 府大講座 酵素のパワーを活かしたものづくり ~生体触媒化学への誘い~

    2014.04 - 2015.03

  • 堺市立堺高等学校サマーサイエンスセミナー 分子における左と右

    2013.04 - 2014.03

  • 高大連携講座 有機分子の世界における左と右

    2011.04 - 2012.03

  • 出前講義 有機分子の世界における左と右

    2006.04 - 2007.03

  • 大阪女子大学公開講座府民教養講座 新薬合成の魔法の手 -不斉合成の話ー

    2003.04 - 2004.03

  • 大阪女子大学公開講座府民教養講座 科学を身近に(A)

    1995.04 - 1996.03

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Visiting Lectures ⇒ Link to the list of Visiting Lectures

  • 有機分子の世界における左と右

    Category:Science (mathematics, physics, chemistry, biology, geology, biochemistry)

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    Audience:Preschooler, Schoolchildren

    Keyword:不斉合成 

    わたしたちが味や香りを感じるメカニズムや、薬がどのように作用するかということが分子のレベルで解き明かされてきました。その背景には、分子の「左と右」の関係の解明にむけた先人たちの数々の努力があります。 左手と右手の関係にある構造の分子の片方だけを巧みに合成する化学への挑戦について解説します。

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  • 研究職歴

    2005.04 - Now

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    大阪府立大学大学院理学系研究科講師