Updated on 2024/04/08

写真a

 
Fukuyama Takahide
 
Organization
Graduate School of Science Department of Chemistry Professor
School of Science Department of Chemistry
Title
Professor
Affiliation
Institute of Science

Position

  • Graduate School of Science Department of Chemistry 

    Professor  2024.04 - Now

  • Graduate School of Science Department of Chemistry 

    Associate Professor  2022.04 - 2024.03

  • School of Science Department of Chemistry 

    Professor  2024.04 - Now

  • School of Science Department of Chemistry 

    Associate Professor  2022.04 - 2024.03

Degree

  • 博士(工学) ( Others )

Research Areas

  • Nanotechnology/Materials / Structural organic chemistry and physical organic chemistry  / 有機化学

  • Life Science / Bioorganic chemistry  / 有機化学

  • Nanotechnology/Materials / Synthetic organic chemistry  / 合成化学

Research subject summary

  • マイクロフローリアクターを用いた有機合成

  • 遷移金属錯体触媒を用いた新反応の開発

Awards

  • 有機合成化学協会関西支部賞 

    2014   有機合成協会関西支部  

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    Country:Japan

  • 研究企画賞

    2002.03   有機合成化学協会  

Papers

  • Site-selectivity in TBADT-photocatalyzed C(sp3)-H Functionalization of Saturated Alcohols and Alkanes Reviewed

    Fukuyama, T.; Yamada, K.; Nishikawa, T.; Ravelli, D.; Fagnoni, M.; Ryu, I.

    Chem. Lett. 雑誌   47 ( 2 )   207 - 209   2018.11

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    Kind of work:Joint Work  

  • Synthesis of Perinaphthenones through Rhodium-Catalyzed Dehydrative Annulation of 1-Naphthoic Acids with Alkynes Reviewed

    Fukuyama, T.; Sugimori, T.; Maetani, S.; Ryu, I.

    Org. Biomol. Chem. 雑誌   16 ( 41 )   7583 - 7587   2018.10

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    Kind of work:Joint Work  

  • ET-Induced Intramolecular Heck Carbonylation Reactions Leading to Benzolactones and Lactams Reviewed

    Fukuyama, T.; Bando, T.; Ryu, I.

    Synthesis 雑誌   50 ( 15 )   3015 - 3021   2018.08

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    Kind of work:Joint Work  

  • Applications of Radical Carbonylation and Amine Addition Chemistry: 1,4-Hydrogen Transfer of 1-Hydroxylallyl Radicals Reviewed

    Matsubara, H.; Kawamoto, T.; Fukuyama, T.; Ryu, I.

    Acc. Chem. Res. 雑誌   51 ( 9 )   2023 - 2035   2018.08

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    Kind of work:Joint Work  

  • Theoretical Calculations for the 1,4-Hydrogen Shift of 1-Hydroxyallyl Radicals Leading to -Keto Radicals; Prediction of Facilitation by 1-Amino and 3-Tin Substituents Reviewed

    Matsubara, H.; Kawamoto, T.; Fukuyama, T.; Ryu, I.

    Chem. Lett. 雑誌   47 ( 9 )   1197 - 1199   2018.07

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    Kind of work:Joint Work  

  • A Theoretical Study on Radical-Based Aminocarbonylation of Aryl Iodides Reviewed

    Kawamoto, T.; Matsubara, H.; Fukuyama, T.; Ryu, I.

    Chem. Lett. 雑誌   47 ( 9 )   1169 - 1171   2018.07

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    Kind of work:Joint Work  

  • Electron Transfer-Induced Reduction of Organic Halides with Amines Reviewed

    Fukuyama, T.; Fujita, Y.; Miyoshi, H. Ryu, I.; Kao, S.-C. Wu, Y.-K.

    Chem. Commun. 雑誌   54 ( 44 )   5582 - 5585   2018.05

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    Kind of work:Joint Work  

  • Site-Selective C-H Functionalization by Decatungstate Anion Photocatalysis: Synergistic Control by Polar and Steric Effects Expands the Reaction Scope Reviewed

    Ravelli, D.; Fagnoni, M.; Fukuyama, T.; Nishikawa, T. Ryu, I.

    ACS Catal 雑誌   8 ( 1 )   701 - 713   2018.01

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    Kind of work:Joint Work  

  • Scalable Flow Synthesis of [6,6]-Phenyl-C61-Butyric Acid Methyl Ester (PCBM) Using a Flow Photo-Reactor with a Na lamp, Reviewed

    Ueda, M.; Imai, N.; Yoshida, S.; Yasuda, H.; Fukuyama, T.; Ryu, I.

    Eur. J. Org. Chem. 雑誌   2017 ( 44 )   6483 - 6485   2017.12

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    Kind of work:Joint Work  

  • Photocatalyzed Site-Selective C(sp3)–H Functionalization of Alkylpyridines at Non-Benzylic Positions Reviewed

    Fukuyama, T.; Nishikawa, T.; Yamada, K.; Ravelli, D.; Fagnoni, M.; Ryu, I.

    Org. Lett. 雑誌   19 ( 23 )   6436 - 6439   2017.11

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    Kind of work:Joint Work  

  • Bromine-Radical-Mediated Synthesis of β-Functionalized β,γ- and δ,ε-Unsaturated Ketones via C–H Functionalization of Aldehydes Reviewed

    Kippo, T.; Kimura, K.; Ueda, M.; Fukuyama, T.; Ryu, I.

    Synlett 雑誌   28 ( 14 )   1733 - 1737   2017.10

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    Kind of work:Joint Work  

  • Bromoallylation of Alkenes Leading to 4-Alkenyl Bromides Based on Trapping of β-Bromoalkyl Radicals, Reviewed

    Kippo, T.; Hamaoka, K.; Ueda, M.; Fukuyama, T.; Ryu, I.

    Org. Lett. 雑誌   19 ( 19 )   5198 - 5200   2017.09

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    Kind of work:Joint Work  

  • Cooperative Polar/Steric Strategy in Achieving Site—Selective Photocatalyzed C(sp3)−H Functionalization Reviewed

    Yamada, K.; Fukuyama, T.; Fujii, S.; Ravelli, D.; Fagnoni, M.; Ryu, I.

    Chem. Eur. J. 雑誌   23 ( 36 )   8615 - 8618   2017.06

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    Kind of work:Joint Work  

  • Ionic Liquids Are not Innocent in Pd Catalysis. C-H Arylation of Thiazolium and Imidazolium Ionic Liquids with Aryl Halides Reviewed

    Fukuyama, T.; Rahman, M. T.; Mashima, H.; Takahashi, H. Ryu, I.

    Org. Chem. Front. 雑誌   4 ( 9 )   1863 - 1866   2017.06

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    Kind of work:Joint Work  

  • Photoredox-Catalyzed Hydrodifluoroalkylation of Alkenes Using Difluorohaloalkyl Compounds and a Hantzsch Ester Reviewed

    Sumino, S.; Uno, M.; Fukuyama, T.; Ryu, I.; Matsuura, M.; Yamamoto, A.; Kishikawa, A.

    J. Org. Chem. 雑誌   82 ( 10 )   5469 - 5474   2017.05

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    Kind of work:Joint Work  

  • Efficient Flow Fischer Esterification of Carboxylic Acids with Alcohols Using Sulfonic Acid-Functionalized Silica as Supported Catalyst Reviewed

    Furuta, A. Fukuyama,T.; Ryu, I.

    Bull. Chem. Soc. Jpn. 雑誌   90 ( 5 )   607 - 612   2017.04

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    Kind of work:Joint Work  

  • Efficient Anionic Ring Opening Polymerization of Ethylene Oxide under Microfluidic Conditions, Reviewed

    Furuta, A. Okada, K.; Fukuyama, T.

    Bull. Chem. Soc. Jpn. 雑誌   90 ( 7 )   838 - 842   2017.04

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    Kind of work:Joint Work  

  • Flow Dehydration and Hydrogenation of Allylic Alcohols: Application to the Waste-Free Synthesis of Pristane Reviewed

    Furuta, A.; Hirobe, Y.; Fukuyama, T.; Ryu, I.; Manabe, Y.; Fukase, K.

    Eur. J. Org. Chem. 雑誌   2017 ( 10 )   1365 - 1368   2017.03

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    Kind of work:Joint Work  

  • Versatile Cross-Dehydrogenative Coupling of Heteroaromatics and Hydrogen Donors via Decatungstate Photocatalysis, Wuattrini, M. C.; Fujii, S. Reviewed

    Wuattrini, M. C.; Fujii, S.; Yamada, K. Fukuyama, T.; Ravelli, D.; Fagnoni, M.; Ryu, I.

    Chem. Commun. 雑誌   53 ( 15 )   2335 - 2338   2017.01

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    Kind of work:Joint Work  

  • Formal Total Synthesis of l-Ossamine via Decarboxylative Functionalization Using Visible-Light-Mediated Photoredox Catalysis in a Flow System Reviewed

    Inuki, S.; Sato, K.; Fukuyama, T.; Ryu, I.; Fujimoto, Y.

    J. Org. Chem. 雑誌   82 ( 2 )   1248 - 1253   2017.01

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    Kind of work:Joint Work  

  • Radical Bromoallylation of Alkynes Leading to 1-Bromo-1,4-dienes Reviewed

    Kippo, T.; Hamaoka, K.; Ueda, M.; Fukuyama T.; Ryu, I.

    Tetrahedron 雑誌   72 ( 48 )   7866 - 7874   2016.12

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    Kind of work:Joint Work  

  • Flow Update for a Cossy Photocyclization, Reviewed

    Fukuyama, T.; Fujita, Y.; Rashid, M. A.; Ryu, I.

    Org. Lett. 雑誌   18 ( 20 )   5444 - 5446   2016.10

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    Kind of work:Joint Work  

  • A Greener Process for Fow C-H Chlorination of Cyclic Alkanes Using in situ Generation and on-site Consumption of Chlorine Gas, Reviewed

    Fukuyama, T.; Tokizane, M.; Matsui, A.; Ryu, I

    React. Chem. Eng. 雑誌   1 ( 6 )   613 - 615   2016.09

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    Kind of work:Joint Work  

  • Carbonylative Mizoroki-Heck Reaction of Alkyl Iodides with Arylalkenes Using a Pd/Photoirradiation System Reviewed

    Sumino, S.; Ui, T.; Hamada, Y.; Fukuyama, T.; Ryu, I.

    Org. Lett. 雑誌   17 ( 20 )   4952 - 4955   2015.10

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    Kind of work:Joint Work  

  • Photocatalytic One-Pot Synthesis of Homoallyl Ketones via Norrish Type I Reaction of Cyclopentanones Reviewed

    Okada, M.; Yamada, K.; Fukuyama, T.; Ravelli, D.; Fagnoni, M. Ryu, I.

    J. Org. Chem. 雑誌   80 ( 18 )   9365 - 9369   2015.08

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    Kind of work:Joint Work  

  • Coupling-Reagent-Free Synthesis of Dipeptides and Tripeptides Using Amino Acid Ionic Liquids Reviewed

    Furukawa, S.; Fukuyama, T.; Matsui, A. Kuratsu, M.; Ineyama, T.; Nakaya, R.; Ryu, I.

    Chem. Eur. J. 雑誌   21 ( 34 )   11980 - 11983   2015.07

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    Kind of work:Joint Work  

  • Photocatalyzed Site-Selective C–H to C–C Conversion of Aliphatic Nitriles, Reviewed

    Yamada, K.; Okada, M.; Fukuyama, T.; Ravelli, D.; Fagnoni, M. Ryu, I.

    Org. Lett. 雑誌   17 ( 5 )   1292 - 1295   2015.02

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    Kind of work:Joint Work  

  • Flow Update for the Carbonylation of-Silyl-Substituted Organolithiums under CO Pressure Reviewed

    Fukuyama, T.; Totoki, T.; Ryu, I.

    Org. Lett. 雑誌   16 ( 21 )   5632 - 5635   2014.10

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    Kind of work:Joint Work  

  • Revisiting Bromination of C-H Bonds with Molecular Bromine Using a Photo-Microflow System Reviewed

    Manabe, Y.; Kitawaki, Y.; Nagasaki, M.; Fukase, K.; Matsubara, H.; Hino, Y.; Fukuyama, T.; Ryu, I.

    Chem. Eur. J. 雑誌   20 ( 40 )   12750 - 12753   2014.09

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    Kind of work:Joint Work  

  • Synthesis of Fluorenones through Rhodium-Catalyzed Intramolecular Acylation of Biarylcarboxylic Acids, Reviewed

    Fukuyama, T.; Maetani, S.; Miyagawa, S.; Ryu, I.

    Org. Lett. 雑誌   16 ( 12 )   3216 - 3219   2014.06

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    Kind of work:Joint Work  

  • Flow Carbonylation Using Near-stoichiometric Carbon Monoxide. Application to Heck Carbonylation, Reviewed

    Akinaga, H.; Masaoka, N.; Takagi, K.; Fukuyama, T.; Ryu, I.

    Chem. Lett. 雑誌   43 ( 9 )   1456 - 1458   2014.05

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    Kind of work:Joint Work  

  • Sunlight Photocatalyzed Regioselective β-Alkylation and Acylation of Cyclopentanones Reviewed

    Okada, M.; Fukuyama, T.; Yamada, K.; Ryu, I.; Ravelli, D.; Fagnoni, M.

    Chem. Sci. 雑誌   5 ( 7 )   2893 - 2898   2014.05

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    Kind of work:Joint Work  

  • Borohydride Mediated Radical Addition Reactions of Organic Iodides to Electron-Deficient Alkenes, Kawamoto, T.; Uehara, S.; Hirao, H.; Fukuyama, T.; Matsubara, H. Reviewed

    Kawamoto, T.; Uehara, S.; Hirao, H.; Fukuyama, T.; Matsubara, H.; Ryu, I.

    J. Org. Chem. 雑誌   79 ( 9 )   3999 - 4007   2014.04

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    Kind of work:Joint Work  

  • Carbonylation Reactions of Alkyl Iodides through the Interplay of Carbon Radicals and Pd Catalysts Reviewed

    Sumino, S.; Fusano, A.; Fukuyama, T.; Ryu, I.

    Acc. Chem. Res. 雑誌   47 ( 5 )   1563 - 1574   2014.04

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    Kind of work:Joint Work  

  • Radical Vinylation of Dioxolanes and N-Acylpyrrolisines Using Vinyl Bromides Reviewed

    Kippo, T.; Kimura, Y.; Maeda, A.; Matsubara, H.; Fukuyama, T.; Ryu, I.

    Org. Chem. Front. 雑誌   1 ( 7 )   755 - 758   2014.03

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    Kind of work:Joint Work  

  • One-pot Synthesis of Cyanohydrin Derivatives from Alkyl Bromides via Incorporation of Two One-Carbon Components by Consecutive Radical/Ionic Reactions Reviewed

    Sumino, S., Fusano, A.; Okai, H.; Fukuyama, T.; Ryu, I.

    Beilstein, J. Org. Chem. 雑誌   10 ( 1 )   150 - 154   2014.01

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    Kind of work:Joint Work  

  • Carbonylation in Microflow: Close Encounters of CO and Reactive Species Reviewed

    Fukuyama, T.; Totoki, T.; Ryu, I.

    Green Chem 雑誌   16 ( 4 )   2042 - 2050   2014.01

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    Kind of work:Joint Work  

  • Ruthenium-Catalyzed Addition of 1,3-Diketones to Terminal Alkynes, Reviewed

    Leotard, B., Fukuyama, T.; Higashibeppu, Y.; Brancour, C.; Okamoto, H.; Ryu, I.

    Synlett 雑誌   24 ( 17 )   2287 - 2291   2013.09

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    Kind of work:Joint Work  

  • Flow Giese Reaction Using Cyanoborohydride as a Radical Mediator Reviewed

    Fukuyama, T.; Kawamoto, T.; Kobayashi, M.; Ryu, I.

    Beilstein J. Org. Chem. 雑誌   9 ( 8 )   2013.08

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    Kind of work:Joint Work  

  • Ruthenium Hydride/Nitrogen Tridentate Ligand-Catalyzed α-Alkylation of Acetamides with Primary Alcohols Reviewed

    Kuwahara, T.; Fukuyama, T.; Ryu, I.

    RSC Adv. 雑誌   3 ( 33 )   13702 - 13704   2013.07

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    Kind of work:Joint Work  

  • Synthesis of Alkylated Nitriles by [RuHCl(CO)(PPh3)3]-catalyzed Alkylation of Acetonitrile Using Primary Alcohols Reviewed

    Kuwahara, T.; Fukuyama, T.; Ryu, I.

    Chem. Lett 雑誌   42 ( 10 )   1163 - 1165   2013.06

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    Kind of work:Joint Work  

  • Modernized Low Pressure Carbonylation Methods in Batch and Flow Employing Common Acids as a CO Source, Reviewed

    Brancour, C.; Fukuyama, T.; Mukai, Y.; Skrydstrup, T.; Ryu, I.

    Org. Lett. 雑誌   15 ( 11 )   2794 - 2797   2013.05

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    Kind of work:Joint Work  

  • Continuous Microflow Bromination of Alkenes Combined with a Circulatory Recycling of a Fluorous Polyether as a Bromine Support, Reviewed

    Fukuyama, T.; Rahman, M. T.; Kamata, N.; Tokizane, M.; Fukuda, Y.; Ryu, I.

    J. Flow Chem. 雑誌   3   4 - 6   2013.05

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    Kind of work:Joint Work  

  • Efficient C–H/C–N and C–H/C–CO–N Conversion via Decatungstate-Photoinduced Alkylation of Diisopropyl Azodicarboxylate Reviewed

    Ryu, I.; Tani, A.; Fukuyama, T.; Ravelli, D.; Montanaro, S.; Fagnoni, M.

    Org. Lett. 雑誌   15 ( 10 )   2554 - 2557   2013.05

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    Kind of work:Joint Work  

  • Rhodium-Catalyzed Decarbonylative C–H Arylation of 2-Aryloxybenzoic Acids Leading to Dibenzofuran Derivatives Reviewed

    Maetani, S.; Fukuyama, T.; Ryu, I.

    Org. Lett. 雑誌   15 ( 11 )   2754 - 2757   2013.05

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  • Free-Radical-Mediated [2+2+1] Cycloaddition of Acetylenes, Amidines, and CO Leading to Five-Membered α,β-Unsaturated Lactams, Reviewed

    Fukuyama, T.; Nakashima, N.; Okada, T.; Ryu, I.

    J. Am. Chem. Soc. 雑誌   135 ( 3 )   1006 - 1008   2013.01

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    Kind of work:Joint Work  

  • 100 Gram Scale Synthesis of a Key Intermediate of Matrix Metalloproteinase Inhibitor in a Continuous-Flow System Based on a Copper-Free Sonogashira Reaction Using an Ionic Liquid as a Catalyst Support Reviewed

    Fukuyama, T.; Rahman M. T.; Sumino, Y.; Ryu, I.

    Synlett 雑誌   23 ( 15 )   2279 - 2283   2012.09

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    Kind of work:Joint Work  

  • RuHCl(CO)(PPh3)3-Catalyzed α-Alkylation of Ketones with Primary Alcohols Reviewed

    Kuwahara, T.; Fukuyama, T.; Ryu, I.

    Org. Lett 雑誌   14 ( 18 )   4703 - 4705   2012.08

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    Kind of work:Joint Work  

  • Pd/Light-Accelerated Atom-Transfer Carbonylation of Alkyl Iodides: Applications in Multicomponent Coupling Processes Leading to Functionalized Carboxylic Acid Derivatives Reviewed

    Fusano, A.; Sumino, S.; Nishitani, S.; Inoue, T.; Morimoto, K.; Fukuyama, T.; Ryu, I.

    Chem. Eur. J. 雑誌   18 ( 30 )   9415 - 9422   2012.07

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    Kind of work:Joint Work  

  • Synthesis of Carbamoylacetates from α-Iodoesters, CO, and Amines under Pd/Light Combined Conditions, Sumino, S. Reviewed

    Sumino, S.; Fusano, A.; Fukuyama, T.; Ryu, I.

    Synlett 雑誌   23 ( 9 )   1331 - 1334   2012.07

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  • Rh-Catalyzed [5+1] and [4+1] Cycloaddition Reaction of 1,4-Enyne Esters with CO. Shortcut to Functionalized Resorcinols and Cyclopentenones Reviewed

    Fukuyama, T.; Ohta, Y.; Brancour, C.; Miyagawa, K.; Ryu, I.; Dhimane, A.; Fensterbank, L.; Malacria, M.

    Chem. Eur. J. 雑誌   18 ( 23 )   7243 - 7247   2012.06

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    Kind of work:Joint Work  

  • Nitroxide Mediated Polymerization of Styrene, n-Butyl Acrylate and Methyl Methacrylate Using Microflow Reactor Technology Reviewed

    Fukuyama, T.; Kajihara, Y.; Ryu, I.; Studer, A.

    Synthesis 雑誌   44 ( 16 )   2555 - 2559.   2012.01

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    Kind of work:Joint Work  

  • Radical Addition of Alkyl Halides to Formaldehyde in the Presence of Cyanoborohydride as a Radical Mediator. A New Protocol for Hydroxymethylation Reaction Reviewed

    Kawamoto, T.; Fukuyama, T.; Ryu, I.

    J. Am. Chem. Soc. 雑誌   134 ( 2 )   875 - 877   2012.01

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  • Iron-catalyzed Decarbonylation Reaction of Aliphatic Carboxylic Acids Leading to α-Olefins Reviewed

    Maetani, S.; Fukuyama, T.; Suzuki, N.; Ishihara, D.; Ryu, I.

    Chem. Commun 雑誌   48 ( 19 )   2552 - 2554   2012.01

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  • Diaryl Ketone Synthesis by [RuHCl(CO)(PPh3)3]-catalyzed Coupling Reaction of Arylboronic Acids with Aryl Aldehydes Reviewed

    Fukuyama, T.; Okamoto, H.; Ryu, I.

    Chem. Lett 雑誌   40 ( 12 )   1453 - 1455.   2011.12

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  • Copper-Free Sonogashira Coupling Reaction in Phosphonium Amino Acid Ionic Liquids Reviewed

    Fukuyama, T.; Rahman, M. T.; Maetani, S.; Ryu, I.

    Chem. Lett. 雑誌   40 ( 9 )   1027 - 1029   2011.09

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    Kind of work:Joint Work  

  • Koch–Haaf Reaction of Adamantanols in an Acid-tolerant Hastelloy-made Microreactor Reviewed

    Fukuyama, T.; Mukai, Y.; Ryu, I.

    Beilstein J. Org. Chem. 雑誌   7 ( 7 )   1288 - 1293.   2011.09

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  • Et2MeN·HI-Catalyzed Reaction of Arylboronic Acids with 2-Acyl-2,3-dihydro-4H-pyrans Leading to 2-Aryltetrahydrocyclopenta- [1,3,2]dioxaboroles Reviewed

    Fukuyama, T.; Okamura, T.; Ryu, I.

    Synthesis 雑誌   ( 10 )   1537 - 1540   2011.07

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  • Continuous Microflow [2 + 2] Photocycloaddition Reactions Using Energy-saving Compact Light Sources Reviewed

    Fukuyama, T.; Kajihara, Y.; Hino, Y.; Ryu, I.

    J. Flow Chem. 雑誌   1 ( 1 )   40 - 45   2011.07

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  • Radical Carbonylation of ω-Alkynylamines Leading to α-Methylene Lactams. Synthetic Scope and the Mechanistic Insights Reviewed

    Ryu, I.; Fukuyama, T.; Tojino, M.; Uenoyama, Y.; Yonamine, Y.; Terasoma, N.; Matsubara, H.

    Org. Biomol. Chem. 雑誌   9 ( 10 )   3780 - 3786.   2011.03

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  • Vicinal C-Functionalization of Alkenes. Pd/ Light-Induced Multi-Component Coupling Reactions Leading to 4-Keto Esters and Lactones Reviewed

    Fusano, A.; Sumino, S.; Fukuyama, T.; Ryu, I.

    Org. Lett. 雑誌   13 ( 8 )   2114 - 2117   2011.03

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  • Efficient Iridium-Catalyzed Decarbonylation Reaction of Aliphatic Carboxylic Acids Leading to Internal or Terminal Alkenes Reviewed

    Maetani, S.; Fukuyama, T.; Suzuki, N.; Ishihara, D.; Ryu, I.

    Organometallics 雑誌   30 ( 6 )   1389 - 1394   2011.02

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  • Atom-Economical Synthesis of Unsymmetrical Ketones through Photocatalyzed C-H Activation of Alkanes and Coupling with CO and Electrophilic Alkenes Reviewed

    Ryu, I.; Tani, A.; Fukuyama, T.; Ravelli, D.; Fagnoni, M.; Albini, A.

    Angew. Chem. Int. Ed. 雑誌   50 ( 8 )   1869 - 1872.   2011.01

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  • Thermal Retro-Aldol Reaction Using Fluorous Ether F-626 as a Reaction Medium, Reviewed

    Fukuyama, T.; Kawamoto, T.; Okamura, T.; Denichoux, A.; Ryu, I.

    Synlett 雑誌   ( 14 )   2193 - 2196   2010.09

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  • Regioselective Synthesis of 1-Bromo-1,4-Dienes by Free-Radical-Mediated Bromoallylation of Activated Acetylenes Reviewed

    Kippo, T.; Fukuyama, T.; Ryu, I.

    Org. Lett. 雑誌   12 ( 18 )   4006 - 4009   2010.08

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  • Monolithic and Flexible Polyimide Film Microreactors for Organic Microchemical Applications Fabricated by Laser Ablation Reviewed

    Min, K.-I.; Lee, T.-H.; Park, C. P.; Wu, Z.-Y.; Girault, H. H.; Ryu, I.; Fukuyama, T.; Mukai, Y.; Kim, D.-P.

    Angew. Chem. Int. Ed. 雑誌   49 ( 39 )   7063 - 7067   2010.06

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  • Regioselective Radical Bromoallylation of Allenes Leading to 2-Bromo-Substituted 1,5-Dienes, Reviewed

    Kippo, T.; Fukuyama, T.; Ryu, I.

    Org. Lett 雑誌   13 ( 15 )   3864 - 3867   2010.06

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  • Synthesis of Functionalized Resorcinols by Rhodium-Catalyzed [5+1] Cycloaddition Reaction of 3-Acyloxy-1,4-Enynes with CO, Reviewed

    Brancour, C.; Fukuyama, T.; Ohta, Y.; Ryu, I. Dhimane, A.-L.; Fensterbank, L.; Malacria, M.

    Chem. Commun. 雑誌   46 ( 30 )   5470 - 5472.   2010.06

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  • Diastereoselective [2+2] Photocycloaddition of Chiral Cyclic Enone and Cyclopentene Using a Microflow Reactor System, Reviewed

    Tsutsumi, K.; Terao, K.; Yamaguchi, H.; Yoshimura, S.; Morimoto, T.; Kakiuchi, K.; Fukuyama, T.; Ryu, I.

    Chem. Lett. 雑誌   39 ( 8 )   828 - 829   2010.06

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  • Black-Light-Induced Radical/Ionic Hydroxymethylation of Alkyl Iodides with Atmospheric CO in the Presence of Tetrabutylammonium Borohydride Reviewed

    Koayashi, S.; Kawamoto, T.; Uehara, S.; Fukuyama, T.; Ryu, I.

    Org. Lett.   12 ( 7 )   1548 - 1551   2010.04

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  • Synthesis of Alkyl Alkynyl Ketones by Pd/Light-Induced Three-Component Coupling Reactions of Iodoalkanes, CO, and 1-Alkynes Reviewed

    Fusano, A.; Fukuyama, T.; Nishitani, N.; Inouye, T.; *Ryu, I.

    Org. Lett. 雑誌   12 ( 10 )   2410 - 2413   2010.04

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  • Stannylcarbonylation of Hydroxy-substituted Alkynes. Intramoleuclar Trapping of alpha-Ketenyl Radicals by a Hydroxy Group Leading to Lactols Reviewed

    Ryu, I.; Fukuyaama, T.; Nobuta, O.; Uenoyama, Y.

    Bull. Kor. Chem. Soc   31 ( 3 )   545 - 546   2010.03

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  • Synthesis of 2-Hydroxymethyl Ketones by Ruthenium Hydride-Catalyzed Cross-Coupling Reaction of alpha,beta-Unsaturated Aldehydes with Primary Alcohols Reviewed

    Denichoux, A.; Fukuyama, T.; Doi, T.; Horiguchi, J.; Ryu, I.

    Org. Lett   12 ( 1 )   2010.01

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  • An automated-flow microreactor system for quick optimization and production: application of 10-and 100-gram order productions of a matrix metalloproteinase inhibitor using a Sonogashira coupling reaction Reviewed

    Sugimoto, A.; Fukuyama, T.; Rahman, M. T.; Ryu, I.

    Tetrahedron Lett.   50 ( 46 )   6364 - 6367   2009.11

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  • Addition of allyl bromide to phenylacetylene catalyzed by palladium on alumina and its application to a continuous flow synthesis Reviewed

    Fukuyama, T.; Kippo, T.; Ryu, I. Sagae, T.

    Res. Chem. Intermediate   35 ( 41860 )   1053 - 1058   2009.11

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  • Hydroruthenation triggered catalytic conversion of dialdehydes and keto aldehydes to lactones Reviewed

    Omura, S.; Fukuyama, T.; Murakami, Y.; Okamoto, H.; Ryu, I.

    Chem. Commun.   ( 44 )   6741 - 6743   2009.11

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  • Radical carbonylations using a continuous microflow system Reviewed

    Fukuyama, T.; Rahman, M. T.; Kamata, N.; Ryu, I.

    Beilstein J. Org. Chem.   5   2009.07

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  • Microflow Radical Carboaminoxylations with a Novel Alkoxyamine Reviewed

    Wienhofer, I. C.; Atuder, A.; Rahman, M. T.; Fukuyama, T.; Ryu, I.

    Org. Lett.   11 ( 11 )   2457 - 2460   2009.06

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  • Generation and Trapping of Cyclopentenylidene Gold Species: Four Pathways to Polycyclic Compounds Reviewed

    Lemiere, G.; Gandon, V.; Cariou, K.; Hours, A.; Fukuyama, T,; Dhimane, A.L.; Fensterbank, L.; Malacria, M.

    J. Am. Chem. Soc.   131 ( 8 )   2993 - 3006   2009.03

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  • Microflow photo-radical reaction using a compact light source: application to the Barton reaction leading to a key intermediate for myriceric acid A Reviewed

    Sugimoto, A.; Fukuyama, T.; Sumino, Y.; Takagi, M.; Ryu, I.

    Tetrahedron   65 ( 8 )   1593 - 1598   2009.02

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  • Ruthenium Hydride-Catalyzed Addition of Aldehydes to Dienes Leading to beta,gamma-Unsaturated Ketones Reviewed

    Omura, S.; Fukuyama, T.; Horiguchi, J.; Murakami, Y.; Ryu, I.

    J. Am. Chem. Soc.   130 ( 43 )   14094 - 14095   2008.10

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  • Tin-Free Giese Reaction and the Related Radical Carbonylation Using Alkyl Iodides and Cyanoborohydrides Reviewed

    I. Ryu, S. Uehara, H. Hirao, T. Fukuyama

    Org. Lett. 雑誌   10 ( 5 )   1005 - 1008   2008.02

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  • Spurring Radical Reactions of Organic Halides with Tin Hydride and TTMSS Using Microreactors Reviewed

    T. Fukuyama, M. Kobayashi, Md. Rahman, N. Kamata, I. Ryu

    Org. Lett. 雑誌   10 ( 4 )   533 - 536   2008.01

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  • Advantures in inner space : Microflow systems for practical organic synthesis Reviewed

    T. Fukuyama, Md. Rahman, M, Sato, I. Ryu

    Synlett 雑誌   ( 2 )   151 - 163   2008.01

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  • Ruthenium Hydride Catalyzed Regioselective Addition of Aldehydes to Enones to Give 1,3-Diketones Reviewed

    T. Fukuyama, T. Doi, S. Minamino, S. Omura, I. Ryu

    Angew. Chem. Int. Ed. 雑誌   46 ( 29 )   5559 - 5561   2007.07

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  • Tandem Gold(I)-Catalyzed Cyclization/Electrophilic Cyclopropantion of Vinyl Allene Reviewed

    G. Lemiere, V. Gandon, K. Cariou, T. Fukuyama, A.L. Dhimane, L. Fensterbank, M. Malacria

    Org. Lett. 雑誌   9 ( 11 )   2207 - 2209   2007.05

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  • Synthesis of lactams by radical substitution reaction of alpha,beta-unsaturated acyl radicals at amine nitrogen Reviewed

    Y. Uenoyama, T. Fukuyama, I. Ryu

    Org. Lett. 雑誌   vol 9 ( No 5 )   935 - 937   2007.03

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  • Ru-Catalyzed intermolecular [3+2+1] cycloaddition of alpha,beta-unsaturated ketones with silylacetylenes and carbon monoxide leading to alpha-pyrones Reviewed

    T. Fukuyama, Y. Higashibeppu, R. Yamaura, I. Ryu

    Org. Lett. 雑誌   vol 9 ( No 4 )   587 - 589   2007.02

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  • Atom transfer caronylation using ionic liquids as reaction media Reviewed

    T.Fukuyama, T. Inouye, I. Ryu

    J.Organomet. Chem. 雑誌   Vol 692 ( No 1-3 )   685 - 690   2007.01

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  • RuHCl(CO)(PPh)3-catalyzed reductive dimerization of alpha,beta-unsaturated aldehydes leading to alpha-hydroxymethyl ketones Reviewed

    T. Doi, T. Fukuyama, S. Minamino, I. Ryu

    Synlett 雑誌   ( No 18 )   3013 - 3016   2006.11

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  • Cascade radical carbonylations leading to 3-substituted cyclohexanones Reviewed

    Y. Uenoyama, T. Fukuyama, I. Ryu

    Synlett 雑誌   ( No 14 )   2342 - 2344   2006.09

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  • Trifluoromethyl-radical mediated carbonylationof alkanes leading to ethynyl ketones Reviewed

    Y. Uenoyama, T. Fukuyama, K. Morimoto, O. Nobuta, H. Nagai, I. Ryu

    Helvetica Chim. Acta 雑誌   vol 89 ( No 10 )   2483 - 2494   2006.09

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  • The Barton reaction using a microreactor and black light. Continuous-flow synthesis of a key steroid intermediate for an endothelin receptor antagonist Reviewed

    A. Sugimoto, Y. Sumino, M. Takagi, T. Fukuyama, I. Ryu

    Tetrahedron Lett. 雑誌   Vol 47 ( No 35 )   6197 - 6200   2006.08

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  • Low pressure Pd-catalyzed carbonylation in an ionic liquid using a multiphase microflow system Reviewed

    M.T. Rahman, T. Fukuyama, N. Kamata, M. Sato, I. Ryu

    Chem. Commun. 雑誌   ( No 21 )   2236 - 2238   2006.06

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  • Selective 6-endo cyclization of the acyl radicals onto the nitrogen of imine and oxazoline C-N bonds Reviewed

    M. Tojino, N. Otsuka, T. Fukuyama, H. Matsubara, I. Ryu

    J. Am. Chem. Soc. 雑誌   Vol 128 ( No 24 )   7712 - 7713   2006.06

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  • High throughput evaluation of the production of substituted acetylenes by the Sonogashira reaction followed by the Mizoroki-Heck reaction in ionic liquids, in situ, using novel array reactor Reviewed

    M. T. Rahman, T. Fukuyama, I. Ryu, K. Suzuki, K. Yonemura, P. F. Hughes, K. Nokihara

    Tetrahedron Lett. 雑誌   Vol 47 ( No 16 )   2703 - 2706   2006.04

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  • An unusual ruthenium hydride-catalyzed dimerization of primary unsaturated alcohols Reviewed

    T. Doi, T. Fukuyama, s. Minamino, G. Husson, I. Ryu

    Chem. Commun. 雑誌   ( No17 )   1875 - 1877   2006.04

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  • RuHCl(CO)(PPh)3-catalyzed chemoselective transfer-hydrogenation of enones leading to saturated ketones Reviewed

    T.Doi, T. Fukuyama, J. Horiguchi, T. Okamura, I. Ryu

    Synlett 雑誌   ( No 5 )   721 - 724   2006.03

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  • Effective acceleration of atom transfer carbonylation of alkyl iodides by metal complexes. Application to the syntesis of the hinokinin precursor and dihydrocapsaicin Reviewed

    T. Fukuyama, S. Nishitani, T. Inouye, K. Morimoto, I. Ryu

    Org. Lett. 雑誌   Vol 8 ( No 7 )   1383 - 1386   2006.03

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  • Synthesis of functionalized hydroquinones via [Cp*RuCl2]2-catalyzed cocyclization of alkynes, alpha,beta-unsaturated carbonyl compounds, and carbon monoxide Reviewed

    T. Fukuyama, R. Yamaura, Y. Higashibeppu, T. Okamura, I. Ryu, T. Kondo, T. Mitsudo

    Org. Lett. 雑誌   Vol 7 ( No 26 )   5781 - 5783   2005.12

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  • An anionic strategy for three- and four component foupling reactions leading to ketone frameworks based on vinylogous conversion of dilithio ketone alpha,beta-dianions Reviewed

    S. Yamato, G. Yamamura, M. Komatsu, M. Arai, T. Fukuyama, I. Ryu

    Org. Lett. 雑誌   Vol 7 ( No 12 )   2489 - 2491   2005.06

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  • Synthsis of acetylenic ketones by a Pd-catalyzed carobnylative three-component coupling reaction In [bmim]PF6 Reviewed

    T. Fukuyama, R. Yamaura, I. Ryu

    Can. J. Chem. 雑誌   Vol 83 ( No 6-7 )   711 - 715   2005.06

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  • Generation of ketone dilithio a,b-dianions and their reactions with electrophiles Reviewed

    H. Nakahira, M. Ikebe, Y. Oku, N. Sonoda, T. Fukuyama, I. Ryu

    Tetrahedron 雑誌   Vo 61 ( No13 )   3383 - 3392   2005.03

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  • Acetylene carbonylation by radicals: Tin radical catalyzed synthesis of a-methylene amides from 1-alkynes, carbon monoxide, and amines Reviewed

    Uenoyama Y, Fukuyama T, Nobuta O, Matsubara H, Ryu I

    Angew. Chem. Int. Ed. 雑誌   Vol 44 ( No 7 )   1075 - 1078   2005.02

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  • Mizoroki-Heck arylation of a,b-unsaturated acids with a hybrid fluorous ether, F-626: Facile filtrative separation of products and efficient recycling of a reaction medium containing a catalyst Reviewed

    T. Fukuyama, M. Arai, H. Matsubara, I. Ryu

    J. Org. Chem. 雑誌   Vol 69 ( No 23 )   8105 - 8107   2004.11

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  • Intramolecular nucleophilic carbonyl trapping of a-ketenyl radicals by an amino group Reviewed

    M. Tojino, Y. Uenoyama, T. Fukuyama, I. Ryu

    Chem. Commun. 雑誌   ( No 21 )   2482 - 2483   2004.11

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  • Quick execution of [2+2] type photochemical cycloaddition reaction by continuous flow system using a glass-made microreactor Reviewed

    T. Fukuyama, Y. Hino, N. Kamata, I. Ryu

    Chem. Lett. 雑誌   vol 33 ( No 11 )   1430 - 1431   2004.10

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  • [Bmim]NTf2, a low viscosity ionic liquid is a viable reaction medium for Pd-catalyzed cross-coupling reactions Reviewed

    S. Liu, T. Fukuyama, M. Sato, I. Ryu

    Synlett 雑誌   ( No 10 )   1814 - 1816   2004.08

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  • Radical carbonylation of 1,5-enynes using TTMSS as a chain carrier. Unexpected formation of persistent 3-silyl-1-siloxyallyl radicals serving as a chain breaking path Reviewed

    T. Fukuyama, Y. Uenoyama, S. Oguri, N. Otuska, I. Ryu

    Chem. Lett. 雑誌   Vol 33 ( No 7 )   854 - 855   2004.07

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  • Ruthenium- and rhodium-catalyzed direct carbonylation of the ortho C-H bond in the benzene ring of N-arylpyrazoles Reviewed

    T, Asaumi, T, Matsuo, T, Fukuyama, Y, Ie, F, Kakiuchi, N. Chatani

    J. Org. Chem. 雑誌   Vol 69 ( No 13 )   4433 - 4440   2004.07

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  • Continuous microflow synthesis of butyl cinnamate by a Mizoroki-Heck reaction using a low viscosity ionic liquids as the recycling reaction medium Reviewed

    S. Liu, T. Fukuyama, M. Sato, I. Ryu

    Org. Process Res. Dev. 雑誌   Vol 8 ( No 3 )   477 - 481   2004.03

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  • Two types of intramolecular homolytic substitution reactions at group XIV atoms: unusual radical 1,4-Sn shifts from Si to C and carbonylative SHi reaction at Si Reviewed

    A. Studer, S. Amrein, H. Matsubara, C. G. Schiesser, T. Doi, T. Kawamura, T. Fukuyama, I. Ryu

    Chem. Commun. 雑誌   ( No 10 )   1190 - 1191   2003.10

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  • Cyclizative radical carbonylation of azaenynes by TTMSS and hexanethiol leading to a-silyl- and thiomethylene lactams. Insights into the E/Z stereoselectivities Reviewed

    M. Tojino, N. Otsuka, T. Fukuyama, H. Matsubara, C. H. Schiesser, H. Kuriyama, H. Miyazato, S. Minakata, M. Komatsu, I. Ryu

    Org. Biomol. Chem 雑誌   Vol 1 ( No 23 )   4262 - 4267   2003.06

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  • Broad-spectrum radical cyclizations boosted by polarity matching. Carbonyltative access to a-stannylmethylene lactams from azaenynes and CO Reviewed

    I. Ryu, H. Miyazato, H. Kuriyama, K. Matsu, M. Tojino, T. Fukuyama, S. Minakata, M. Komatsu,

    J. Am. Chem. Soc. 雑誌   vol 125 ( No 19 )   5632 - 5663   2003.04

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  • A copper-free Sonogashira coupling reaction in ionic liquids and its application to a microflow system for efficient catalyst recycling Reviewed

    Fukuyama T, Shinmen M, Nishitani S, Sato M, Ryu I

    Org. Lett. 雑誌   Vol 4 ( No 10 )   1691 - 1694   2002.04

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  • Cationic organotin clusters for highly efficient alcohol acetylation catalysts Reviewed

    Durand S, Sakamoto K,Fukuyama T, Orita A, Otera J, Duthie A, Dakternieks D, Schulte M, Jurkschat K

    Organometallics 雑誌   Vol 19 ( No 16 )   3220 - 3223   2000.08

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  • Synthesis and structural studies on dimeric organotin cations Reviewed

    Sakamoto K, Ikeda H, Akashi H, Fukuyama T, Orita A, Otera J

    Organometallics 雑誌   Vol 19 ( No 16 )   3242 - 3248   2000.08

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  • A new synthetic route to heteroarylsilanes via ruthenium- catalyzed C-H/SiR3 coupling Reviewed

    Kakiuchi F, Matsumoto M, Sonoda M, Fukuyama T, Chatani N, Murai S, Furukawa N, Seki Y

    Chem. Lett. 雑誌   ( No.7 )   750 - 751   2000.07

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  • Acylation of five-membered N-heteroaromatic compounds by ruthenium carbonyl-catalyzed direct carbonylation at a C-H bond Reviewed

    Chatani N, Fukuyama T, Tatamidani H, Kakiuchi F, Murai S

    J. Org. Chem. 雑誌   Vol.65 ( No 13 )   4039 - 4047   2000.06

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  • Direct carbonylation at a C-H bond in the benzene ring of 2- phenyloxazolines catalyzed by Ru-3(CO)(12). Scope, limitations, and mechanistic aspects Reviewed

    Ie Y, Chatani N, Ogo T,Marshall D. R, Fukuyama T, Kakiuchi F, Murai S

    J. Org. Chem. 雑誌   Vol.65 ( No 5 )   1475 - 1488   2000.03

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  • Ru-3(CO)(12)-catalyzed site-selective carbonylation reactions at a C-H bond in aza-heterocycles Reviewed

    Fukuyama T, Chatani N,Tatsumi J, Kakiuchi F, Murai S

    J. Am. Chem. Soc. 雑誌   Vol.120 ( No44 )   11522 - 11523   1998.11

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  • New synthetic method for the preparation of indenones from aromatic imines. Ru-3(CO)(12)-catalyzed carbonylation at an ortho C-H bond in the aromatic imines Reviewed

    Fukuyama T, Chatani N, Kakiuchi F, Murai S

    J. Org. Chem. 雑誌   Vol.62 ( No16 )   5647 - 5650   1997.08

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  • Ru-3(CO)(12)-catalyzed coupling of heteroaromatic C- H/CO/olefins. Regioselective acylation of the imidazole ring

    Chatani N, Fukuyama T, Kakiuchi F, Murai S

    J. Am. Chem. Soc. 雑誌   Vol.118 ( No 2 )   493 - 494   1996.02

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Grant-in-Aid for Scientific Research

  • Innovation in carbonylation reaction using continuous droplet flow technology

    Grant-in-Aid for Scientific Research(C)  2026

  • Innovation in carbonylation reaction using continuous droplet flow technology

    Grant-in-Aid for Scientific Research(C)  2025

  • Innovation in carbonylation reaction using continuous droplet flow technology

    Grant-in-Aid for Scientific Research(C)  2024

Charge of on-campus class subject

  • 化学実験1

    2024   Weekly class   Undergraduate

  • 機器分析法

    2024   Weekly class   Undergraduate

  • 化学特別演習2A

    2024   Intensive lecture   Graduate school

  • 化学特別演習1A

    2024   Intensive lecture   Graduate school

  • 化学特別研究2A

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  • 化学特別研究1A

    2024   Intensive lecture   Graduate school

  • 研究企画ゼミナール

    2024   Intensive lecture   Graduate school

  • 化学特別演習5A

    2024   Intensive lecture   Graduate school

  • 化学特別演習4A

    2024   Intensive lecture   Graduate school

  • 化学特別演習3A

    2024   Intensive lecture   Graduate school

  • 化学特別研究5A

    2024   Intensive lecture   Graduate school

  • 化学特別研究4A

    2024   Intensive lecture   Graduate school

  • 化学特別研究3A

    2024   Intensive lecture   Graduate school

  • 化学実験Ⅱ

    2024   Weekly class   Undergraduate

  • 化学実験Ⅰ

    2024   Weekly class   Undergraduate

  • Chemistry Laboratory I

    2021   Practical Training  

  • Organic Chemistry II

    2021    

  • Organic Chemistry

    2021    

  • Organic Spectroscopy II

    2021    

  • Exercises in Organic Chemistry II

    2021    

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