Updated on 2023/02/15

写真a

 
KOJIMA Chie
 
Organization
Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology Associate Professor
School of Engineering Department of Applied Chemistry
Title
Associate Professor
Affiliation
Institute of Engineering

Position

  • Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology 

    Associate Professor  2022.04 - Now

  • School of Engineering Department of Applied Chemistry 

    Associate Professor  2022.04 - Now

Degree

  • 博士(生命科学) ( Kyoto University )

Research Areas

  • Nanotechnology/Materials / Polymer materials

  • Life Science / Biomaterials  / Biomedical engineering/biological material studies

  • Life Science / Biomedical engineering  / Biomedical engineering/biological material studies

Professional Memberships

  • Japanese Cancer Association

    2019.07 - Now   Domestic

  • The Kinki Chemical Society Japan

    2015.04 - Now   Domestic

  • Japanese Society for Molecular Imaging

    2014.04 - Now   Domestic

  • Japanese Society for Regenerative Medicine

    2014.04 - Now   Domestic

  • The Japanese Peptide Society

    2011.01 - Now   Domestic

  • The Chemical Society of Japan

    2006.12 - Now   Domestic

  • The Japan Society of Drug Delivery System

    2006.03 - Now   Domestic

  • The Society of Polymer Science, Japan

    2005.04 - Now   Domestic

  • Japanese Society for Biomaterials

    2005.04 - Now   Domestic

  • The Japanese Biochemical Society

    2003.04 - Now   Domestic

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Awards

  • Konica Minolta Imaging Science Encouragement Award

    2019.01   Konica Minolta Science and Technology Foundation  

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    Country:Japan

  • The CSJ Award for Women Chemists

    2015.03   The Chemical Society of Japan(CSJ)  

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    Country:Japan

  • SPSJ Award for the Outstanding Paper in Polymer Journal sponsored by ZEON

    2014.05   The Society of Polymer Science  

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    Country:Japan

Papers

  • 生体組織の新規透明化技術

    成相 哲朗, 谷川 潤, 市原 準二, 川村 哲也, 宝来 真志, 児島 千恵

    住友化学   2022   57 - 62   2022.07( ISSN:0387-1312

  • Design of a dendrimer with a matrix metalloproteinase-responsive fluorescence probe and a tumor-homing peptide for metastatic tumor cell imaging in the lymph node Reviewed

    K. Nagai, T. Sato, C. Kojima

    Bioorganic & Medicinal Chemistry Letters 雑誌 Elsevier   33   2021.02

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    Kind of work:Joint Work  

  • Different antifouling effects of random and block copolymers comprising 2-methacryloyloxyethyl phosphorylcholine and dodecyl methacrylate Reviewed

    C. Kojima, R. Katayama, T. L. Nguyen, Y. Oki, A. Tsujimoto, S. Yusa, K. Shiraishi, A. Matsumoto

    Eur. Polymer J. 雑誌 Elsevier   136   2020.08

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    Kind of work:Joint Work  

  • Rapid optical tissue clearing using various anionic polymer hydrogels Reviewed

    C. Kojima, Y. Ono, T. Koda, A. Matsumoto

    Materials Today Communications 雑誌 Elsevier   21   2019.12

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    Kind of work:Joint Work  

  • Rapid optical tissue clearing using poly(acrylamide-co-styrenesulfonate) hydrogels for three-dimensional imaging Reviewed

    Y. Ono, I. Nakase, A. Matsumoto, C. Kojima

    J. Biomed. Mater. Res. B 雑誌 Wiley   107   2297 - 2304   2019.10

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    Kind of work:Joint Work  

  • Formation of hydrophobic domains on the poly(MPC-co-dodecyl methacrylate)-coated surface recognized by macrophage-like cells Reviewed

    R. Katayama, M. Ikeda, K. Shiraishi, A. Matsumoto, C. Kojima

    Langmuir 雑誌 American Chemical Society   35   12229 - 12235   2019.09

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    Kind of work:Joint Work  

  • Modulation of Cell Adhesion and Differentiation on Collagen Gels by the Addition of the Ovalbumin Secretory Signal Peptide Reviewed

    C. Kojima, Y. Narita, Y. Nakajima, N. Morimoto, T. Yoshikawa, N. Takahashi, A. Handa, T. Waku, N. Tanaka

    ACS Biomater. Sci. Eng. 雑誌 American Chemical Society   5 ( 11 )   5698 - 5704   2019.04

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    Kind of work:Joint Work  

  • Controlled release of DNA from zinc and magnesium ion-doped hydroxyapatites Reviewed

    C. Kojima, K. Watanabe, H. Murata, Y. Nishio, R. Makiura, K. Matsunaga, A. Nakahira

    Res. Chem. Intermediates 雑誌 Springer   45   23 - 32   2019.01

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    Kind of work:Joint Work  

  • Design of peptide-dendrimer conjugates with tumor homing and antitumor effects Reviewed

    C. Kojima, K. Saito, E. Kondo,

    Res. Chem. Intermediates 雑誌 Springer   44   4685 - 4695   2018.08

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    Kind of work:Joint Work  

  • Dual pH- and UCST-type thermo-sensitive dendrimers: phenylalanine-modified polyamidoamine dendrimers with carboxyl termini Reviewed

    M. Tamaki, D. Fukushima, C. Kojima

    RSC Advances 雑誌 ROYAL SOCIETY OF CHEMISTRY   8   28147 - 28151   2018

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    Kind of work:Joint Work  

  • Visible laser-induced in situ cell detachment from gold nanoparticle-embedded collagen gel Reviewed

    C. Kojima, Y. Nakajima, N. Oeda, T. Kawano, Y. Taki,

    Macromol. Biosci 雑誌 Wiley   17   2017.05

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    Kind of work:Joint Work  

  • Ovalbumin secretory signal peptide-containing collagen gel as a cell scaffold Reviewed

    C. Kojima, Y. Narita, T. Waku, N. Morimoto, D. Togawa, N. Takahashi, A. Handa, N. Tanaka,

    Chem. Lett 雑誌 日本化学会   46 ( 3 )   395 - 397   2017.03

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    Kind of work:Joint Work  

  • Applications of gold nanoparticle-loaded thermosensitive elastin-mimetic dendrimer to photothermal therapy Reviewed

     C. Kojima, D. Fukushima

    J. Photopolym. Sci. Technol. 雑誌   29 ( 4 )   519 - 523   2016.09

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    Kind of work:Joint Work  

  • Dendrigraft polylysine coated-poly(glycolic acid) fibrous scaffolds for hippocampal neurons Reviewed

    C. Kojima, E. Fusaoka-Nishioka, T. Imai, A. Nakahira, H. Onodera,

    J. Biomed. Mater Res. A 雑誌 Wiley   104   2744 - 2750   2016.07

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    Kind of work:Joint Work  

  • Optimization of dendrimer structure for sentinel lymph node imaging: Effects of generation and terminal group Reviewed

    Y. Niki, M. Ogawa, R. Makiura, Y. Magata, C. Kojima

    Nanomedicine 雑誌   11 ( 8 )   2119 - 2127   2015.11

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    Kind of work:Joint Work  

  • Effect of main chain conformation to thermosensitivity in elastin-like peptide-grafted polylysine Reviewed

    C. Kojima, U. H. Sk, D. Fukushima, K. Irie, N. Akazawa, M. Umeda, T. Niidome

    RSC Advances 雑誌   127 ( 5 )   104900 - 104906   2015.11

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    Kind of work:Joint Work  

  • Ovalbumin delivery by guanidine-terminated dendrimers bearing an amyloid-promoting peptide via nanoparticle formulation Reviewed

    C. Kojima, R. Kameyama, M. Yamada, M. Ichikawa, T. Waku, A. Handa, N. Tanaka

    Bioconjugate Chem. 雑誌 American Chemical Society   26 ( 8 )   1804 - 1810   2015.08

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    Kind of work:Joint Work  

  • Dual stimuli-sensitive dendrimers: photothermogenic gold nanoparticle-loaded thermo-responsive elastin-mimetic dendrimers Reviewed

    D. Fukushima, U. H. Sk, Y. Sakamoto, I. Nakase, C. Kojima

    Colloid Surf. B-Biointerfaces 雑誌 Elsevier   132 ( 1 )   155 - 160   2015.05

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    Kind of work:Joint Work  

  • Prolonged local retention of subcutaneously injected polymers monitored by noninvasive SPECT imaging Reviewed

    C. Kojima, Y. Niki, M. Ogawa, Y. Magata

    Int. J. Pharm 雑誌 ELSEVIER   467 ( 1-2 )   164 - 168   2014.12

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    Kind of work:Joint Work  

  • Temperature-sensitive elastin-mimetic dendrimers: Effect of peptide length and dendrimer generation to temperature sensitivity Reviewed

    C. Kojima, K. Irie, T. Tada, N. Tanaka

    Biopolymers 雑誌 Wiley Periodicals   101 ( 6 )   603 - 612   2014.06

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    Kind of work:Joint Work  

  • Photothermogenic properties of different sized gold nanoparticles for application in photothermal therapy Reviewed

    C. Kojima, N. Oeda, S. Ito, H. Miyasaka, T. Iida

    Chem. Lett. 雑誌 CSJ Pulications   43 ( 7 )   975 - 976   2014.03

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    Kind of work:Joint Work  

  • Synthesis of Temperature-dependent Elastin-like Peptide-modified Dendrimer for Drug Delivery Reviewed

    C. Kojima, K. Irie

    Biopolymers:Peptide Sci. 雑誌 Wiley   100 ( 6 )   714 - 721   2013.11

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    Kind of work:Joint Work  

  • The synthesis and evaluation of polymer prodrug/collagen hybrid gels for delivery into metastatic cancer cells Reviewed

    C. Kojima, E. Nishisaka, T. Suehiro, K. Watanabe, A. Harada, T. Goto, Y. Magata, K. Kono

    Nanomedicine 雑誌 Elsevier   9 ( 6 )   767 - 775   2013.08

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    Kind of work:Joint Work  

  • Synthesis and binding properties of peptidomimetics based on a dendritic polymer Reviewed

    C. Kojima, H. Fukada, T. Inui

    Polymer J 雑誌 Nature Pub. Group   45 ( 8 )   813 - 818   2013.08

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    Kind of work:Joint Work  

  • Preparation of hydroxyapatite-decorated poly(lactide-co-glycolide) microspheres for paclitaxel delivery Reviewed

    C. Kojima, K. Watanabe, T. Nagayasu, Y. Nishio, R. Makiura, A. Nakahira

    J. Nanoparticle Res 雑誌 Springer   15   2013.07

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    Kind of work:Joint Work  

  • Design of a Novel Drug Carrier with Photo-Responsive Properties: Drug-Encapsulated and Alkanethiol-Modified Gold Nanoparticle-Loaded PEGylated Dendrimer Reviewed

    C. Kojima, H. Kawabata, A. Harada, H. Horinaka, K. Kono

    Chem. Lett. 雑誌 CSJ Pulications   42 ( 6 )   612 - 614   2013.04

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    Kind of work:Joint Work  

  • Paclitaxel-loaded hydroxyapatite/collagen hybrid gels as drug delivery systems for metastatic cancer cells Reviewed

    K. Watanabe, Y. Nishio, R. Makiura, A. Nakahira, C. Kojima

    Int. J. Pharm. 雑誌 Elsevier   446   81 - 86   2013.03

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    Kind of work:Joint Work  

  • Doxorubicin-conjugated dendrimer/collagen hybrid gels for metastasis-associated drug delivery system Reviewed

    C. Kojima, T. Suehiro, K. Watanabe, M. Ogawa, A. Fukuhara, E. Nishisaka, A. Harada, K. Kono, T. Inui, Y. Magata

    Acta Biomater. 雑誌 Elsevier   9 ( 3 )   5673 - 5680   2013.03

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    Kind of work:Joint Work  

  • Gold nanoparticle-loaded PEGylated dendrimers for theragnosis Reviewed

    C. Kojima, S.-H. Cho, E. Higuchi

    Res. Chem. Intermed 雑誌 Springer   38 ( 6 )   1279 - 1289   2012.04

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    Kind of work:Joint Work  

  • Adsorption and desorption of bioactive proteins on hydroxyapatite for protein delivery systems Reviewed

    C. Kojima, K. Watanabe

    J. Drug Deliv. 雑誌 Hindawi Publishing Corporation   2012   2012.03

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    Kind of work:Joint Work  

  • Dendrimer-based MRI contrast agents: the effects of PEGylation on relaxivity and pharmacokinetics Reviewed

    C. Kojima, B. Turkbey, M. Ogawa, M. Bernardo, C. A. S. Regino, L. H. Bryant, Jr., P. L. Choyke, K. Kono, H. Kobayashi

    Nanomedicine 雑誌 Elsevier   7 ( 6 )   1001 - 1008   2011.12

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    Kind of work:Joint Work  

  • Improvement of Temperature-responsive Drug Release from Collagen-mimic Dendrimers Reviewed

    C. Kojima, T. Suehiro

    Chem. Lett. 雑誌 CSJ Pulications   40 ( 11 )   1249 - 1251   2011.10

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    Kind of work:Joint Work  

  • Design of Photosensitive Gold Nanoparticles for Biomedical Applications Based on Self-consistent Optical Response Theory Reviewed

    C. Kojima, Y. Watanabe, H. Hattori, T. Iida

    J. Phys. Chem. C 雑誌 American Chemical Society   115 ( 39 )   19091 - 19095   2011.10

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    Kind of work:Joint Work  

  • Preparation of heat-induced artificial collagen gels based on collagen-mimetic dendrimers Reviewed

    C. Kojima, T. Suehiro, T. Tada, Y. Sakamoto, T. Waku, N. Tanaka

    Soft Matter 雑誌 RSC Publishing   7 ( 19 )   8991 - 8997   2011.07

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    Kind of work:Joint Work  

  • Temperature-dependent higher order structures of the (Pro-Pro-Gly)10-modified dendrimer Reviewed

    T. Suehiro, T. Tada, T. Waku, N. Tanaka, C. Hongo, S. Yamamoto, A. Nakahira, C. Kojima

    Biopolymers 雑誌 Wiley Periodicals   95 ( 4 )   270 - 277   2011.04

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    Kind of work:Joint Work  

  • Preparation of near-infrared light absorbing gold nanoparticles using polyethylene glycol-attached dendrimers Reviewed

    C. Kojima, Y. Umeda, A. Harada, K. Kono

    Colloids and Surf. B: Biointerfaces 雑誌 Elsevier B.V.   81 ( 2 )   648 - 651   2010.12

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    Kind of work:Joint Work  

  • Temperature-sensitive hyperbranched poly(glycidol)s with oligo(ethylene glycol) monoethers Reviewed

    C. Kojima, K. Yoshimura, A. Harada, Y. Sakanishi, K. Kono

    J. Polym. Sci. Part A: Polym. Chem. 雑誌 Wiley Periodicals   48 ( 18 )   4047 - 4056   2010.09

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    Kind of work:Joint Work  

  • PEG-attached PAMAM dendrimers encapsulating gold nanoparticles: growing gold nanoparticles in the dendrimers for improvement of their photothermal properties Reviewed

    Y. Umeda, C. Kojima, A. Harada, H. Horinaka, K. Kono

    Bioconjugate Chem. 雑誌 American Chemical Society   21 ( 8 )   1559 - 1564   2010.08

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    Kind of work:Joint Work  

  • Higher order structure of short collagen model peptides attached to dendrimers and linear polymers Reviewed

    T. Suehiro, C. Kojima, S. Tsumura, A. Harada, K. Kono

    Biopolymers 雑誌 Wiley Periodicals   93 ( 7 )   640 - 648   2010.07

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    Kind of work:Joint Work  

  • X-ray computed tomography contrast agents prepared by seeded growth of gold nanoparticle in PEGylated dendrimer Reviewed

    C. Kojima, Y. Umeda, M. Ogawa, A. Harada, Y. Magata, K. Kono

    Nanotechnology 雑誌 IOP Publishing   21 ( 24 )   2010.06

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    Kind of work:Joint Work  

  • Influence of dendrimer generation and polyethylene glycol length on the biodistribution of pegylated dendrimers. Reviewed

    C. Kojima, C. Regino, Y. Umeda, H. Kobayashi, K. Kono

    Int. J. Pharm. 雑誌 Elsevier B.V.   383 ( 1-2 )   293 - 296   2010.01

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    Kind of work:Joint Work  

  • Synthesis and characterization of hyperbranched poly(glycidol) modified with pH- and temperature-sensitive groups. Reviewed

    C. Kojima, K. Yoshimura, A. Harada, Y. Sakanishi, K. Kono

    Bioconjugate Chem. 雑誌 American Chemical Society   20 ( 5 )   1054 - 1057   2009.05

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    Kind of work:Joint Work  

  • A collagen-mimic dendrimer capable of controlled release. Reviewed

    C. Kojima, S. Tsumura, A. Harada, K. Kono

    J. Am. Chem. Soc. 雑誌 American Chemical Society   131 ( 17 )   6052 - 6053   2009.05

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    Kind of work:Joint Work  

  • Aqueous solubilization of fullerenes using poly(amidoamine) dendrimers bearing cyclodextrin and poly(ethylene glycol). Reviewed

    C. Kojima, Y. Toi, A. Harada, K. Kono

    Bioconjugate Chem. 雑誌 American Chemical Society   19 ( 11 )   2280 - 2284   2008.11

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    Kind of work:Joint Work  

  • Preparation and characterization of complexes of liposomes with gold nanoparticles. Reviewed

    C. Kojima, Y. Hirano, E. Yuba, A. Harada, K. Kono

    Colloid Surf. B-Biointerfaces 雑誌 Elsevier B.V.   66 ( 2 )   246 - 252   2008.10

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    Kind of work:Joint Work  

  • Preparation and cytotoxic activity of poly(ethylene glycol)-modified poly(amidoamine) dendrimers bearing adriamycin Reviewed

    K. Kono, C. Kojima, N. Hayashi, E. Nishisaka, K. Kiura, S. Watarai, A. Harada

    Biomaterials 雑誌 Elsevier   29 ( 11 )   1664 - 1675   2008.04

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    Kind of work:Joint Work  

  • Preparation of Poly(ethylene Glycol)-Modified Poly(amidoamine) Dendrimers Encapsulating Gold Nanoparticles and Their Heat-Generating Ability. Reviewed

    Y. Haba, C. Kojima, A. Harada, T. Ura, H. Horinaka, K. Kono

    Langmuir 雑誌 American Chemical Society   23 ( 10 )   5243 - 5246   2007.05

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    Kind of work:Joint Work  

  • Preparation of Poly(ethylene Glycol)-Attached Dendrimers Encapsulating Photosensitizers for Application to Photodynamic Therapy. Reviewed

    C. Kojima, Y. Toi, A. Harada, K. Kono.

    Bioconjugate Chem. 雑誌 American Chemical Society   18 ( 3 )   663 - 670   2007.05

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    Kind of work:Joint Work  

  • Comparison of thermosensitive properties of poly(amidoamine) dendrimers with peripheral N-isopropylamide groups and linear polymers with the same groups. Reviewed

    Y. Haba, C. Kojima, A. Harada, K. Kono

    Angew. Chem. Int. Ed. 雑誌 WILEY-VCH   46 ( 1-2 )   234 - 237   2006.12

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    Kind of work:Joint Work  

  • Thermosensitive Properties of Poly(amidoamine) Dendrimers with Peripheral Phenylalanine Residues Reviewed

    Y. Tono, C. Kojima, Y. Haba, T. Takahashi, A. Harada, S. Yagi, K. Kono

    Langmuir 雑誌 American Chemical Society   22 ( 11 )   4920 - 4922   2006.05

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    Kind of work:Joint Work  

  • Regulation of Bin1 SH3 Domain Binding by Phosphoinositides. Reviewed

    C. Kojima, A. Hashimoto, I. Yabuta, M. Hirose, S. Hashimoto, Y. Kanaho, H. Sumimoto, T. Ikegami, H. Sabe

    EMBO J. 雑誌 Nature Pub. Group   23 ( 22 )   4413 - 4422   2004.11

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    Kind of work:Joint Work  

  • Design of Biocompatible Dendrimers with Environment Sensitivity. Reviewed

    C. Kojima, Y. Haba, T. Fukui, K. Kono, T. Takagishi

    Macromolecules 雑誌 American Chemical Society   36 ( 7 )   2183 - 2186   2003.04

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    Kind of work:Joint Work  

  • Synthesis of Polyamidoamine Dendrimers Having Poly(ethylene glycol) Grafts and Their Ability to Encapsulate Anticancer Drugs. Reviewed

    C. Kojima, K. Kono, K. Maruyama, T. Takagishi

    Bioconjugate Chem. 雑誌 American Chemical Society   11 ( 6 )   910 - 917   2000.11

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    Kind of work:Joint Work  

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Charge of on-campus class subject

  • Drug Delivery System

    2021    

  • Laboratory Training in Drug Discovery Sciences & Technology II

    2021   Practical Training  

  • Laboratory Training in Drug Discovery Sciences & Technology I

    2021   Practical Training  

  • Laboratory Exercises for Applied Chemistry II

    2021   Practical Training  

  • Laboratory Exercises for Applied Chemistry I

    2021   Practical Training  

  • Laboratory Exercises for Applied Chemistry V

    2021   Practical Training  

  • Laboratory Exercises for Applied Chemistry III

    2021   Practical Training  

  • First Year Seminar

    2021    

  • Advanced Nanobiochemistry

    2021    

  • Introduction of Drug Discovery

    2021    

  • Laboratory Exercises for Applied Chemistry IV

    2021   Practical Training  

  • Exercises in Organic Chemistry IIA

    2021    

  • Polymer Chemistry I

    2021    

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