Updated on 2024/08/22

写真a

 
YOSHIDA HISAKO
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Associate Professor
School of Medicine Department of Medical Science
Title
Associate Professor
Affiliation
Institute of Medicine
Contact information
メールアドレス
Affiliation campus
Abeno Campus

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Associate Professor  2023.10 - Now

  • School of Medicine Department of Medical Science 

    Associate Professor  2023.10 - Now

Degree

  • 博士(医学バイオ統計学) ( Kurume University )

Research Interests

  • Risk-Based Monitoring

Professional Memberships

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Committee Memberships (off-campus)

  • 委員   奈良県立医科大学臨床研究審査会  

    2023.06 - Now 

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    臨床研究審査会に出席又は書面で審査資料を確認し、研究の実施の適否等について審査を行う。

  • 委員   奈良県立医科大学医の倫理審査委員会  

    2020.10 - Now 

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    倫理審査委員会に出席又は書面で審査資料を確認し、研究の実施の適否等について審査を行う。

Awards

  • Teacher of the year

    2022.03   大阪市立大学  

  • 日本腹膜透析医学会学術集会 優秀演題賞

    2016.09  

  • 日本腹膜透析医学会学術集会 優秀演題賞

    2011.09  

  • 日本腹膜透析医学会 コメディカル賞

    2009.06  

  • 日本腹膜透析医学会 コメディカル賞

    2008.06  

Job Career (off-campus)

  • 佐賀大学医学部附属病院   臨床研究センター   特任准教授

    2016.04 - 2018.03

  • 九州大学大学院医学研究院   包括的腎不全治療学   寄附講座教員(助教)

    2011.04 - 2016.03

  • 九州大学大学院医学研究院   包括的腎不全治療学   寄附講座教員(客員助教)

    2007.05 - 2011.03

  • 九州大学大学院医学研究院   包括的腎不全治療学   寄附講座教員

    2006.05 - 2007.04

  • 九州大学医学部附属病院   看護部   看護師

    2000.04 - 2006.03

  • 九州大学医学部附属病院   看護部   技能補佐員・技術補佐員

    1999.04 - 2000.03

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Papers

  • Pulse pressure modifies the association between diastolic blood pressure and decrease in kidney function: the Japan Specific Health Checkups Study.

    Tamaki H, Eriguchi M, Yoshida H, Uemura T, Tasaki H, Nishimoto M, Kosugi T, Samejima KI, Iseki K, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kasahara M, Shibagaki Y, Kondo M, Asahi K, Watanabe T, Tsuruya K

    Clinical kidney journal   17 ( 6 )   sfae152   2024.06( ISSN:2048-8505

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  • Blood pressure reduction with empagliflozin in Japanese patients with type 2 diabetes and cardiovascular diseases: a post-hoc sub-analysis of the placebo-controlled randomized EMBLEM trial.

    Tanaka A, Shimabukuro M, Teragawa H, Yoshida H, Okada Y, Takamura T, Taguchi I, Toyoda S, Tomiyama H, Ueda S, Higashi Y, Node K, EMBLEM Investigators

    Hypertension research : official journal of the Japanese Society of Hypertension   2024.05( ISSN:0916-9636

  • Non-linear association between the time required to reaching temperature targets and the neurological outcome in patients undergoing targeted temperature management after out-of-hospital cardiac arrest: Observational multicentre cohort study Reviewed

    Nishimura T, Hatakeyama T, Yoshida H, Yoshimura S, Kiguchi T, Irisawa T, Yamada T, Yoshiya K, Park C, Ishibe T, Yagi Y, Kishimoto M, Kim SH, Hayashi Y, Ito Y, Sogabe T, Morooka T, Sakamoto H, Suzuki K, Nakamura F, Matsuyama T, Okada Y, Nishioka N, Matsui S, Kimata S, Kawai S, Makino Y, Kitamura T, Iwami T, Mizobata Y.

    Resuscitation plus   18   100607   2024.04

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1016/j.resplu.2024.100607

    PubMed

  • More rapid progression of brain atrophy in patients on peritoneal dialysis compared with hemodialysis: The VCOHP Study Reviewed

    Tsuruya K, Yoshida H, Yamada S, Haruyama N, Tanaka S, Tsuchimoto A, Eriguchi M, Fujisaki K, Torisu K, Nakano T, Masutani K, Kitazono T.

    Hypertension research   47   887 - 897   2024.04

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41440-023-01530-5

  • Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD) Reviewed

    Tachibana A, Iga JI, Ozaki T, Yoshida T, Yoshino Y, Shimizu H, Mori T, Furuta Y, Shibata M, Ohara T, Hata J, Taki Y, Mikami T, Maeda T, Ono K, Mimura M, Nakashima K, Takebayashi M, Ninomiya T, Ueno SI; JPSC-AD study group.

    Scientific reports   2024.03

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1038/s41598-024-57922-1

  • Amino acids to prevent cardiac surgery-associated acute kidney injury: a randomized controlled trial Reviewed

    10 ( 1 )   2024.03

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1186/s40981-024-00703-6

    PubMed

  • Utility and optimal dose of nicorandil for physiological assessment of the femoropopliteal artery Reviewed

    Yoshioka N, Shimada T, Iwasaki Y, Yoshida H, Otsuka K, Yamazaki T, Morita Y, Nakamura S, Fukuda D, Morishima I.

    103 ( 4 )   670 - 677   2024.03( ISSN:15221946

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ccd.30976

    PubMed

  • Treatment sequencing after failure to alectinib in patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer Reviewed

    Shimomura Y, Sawa K, Imai T, Ihara Y, Yoshida H, Shintani A.

    115 ( 3 )   926 - 936   2024.03( ISSN:13479032

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/cas.16056

    PubMed

  • Differential associations of fetuin-A and calcification propensity with cardiovascular events and subsequent mortality in patients undergoing hemodialysis Reviewed

    Mori K, Shoji T, Nakatani S, Uedono H, Ochi A, Yoshida H, Imanishi Y, Morioka T, Tsujimoto Y, Kuro-O M, Emoto M.

    17 ( 3 )   2024.02( ISSN:20488505

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ckj/sfae042

    PubMed

  • Survey of students and guardians for assessing the early detection of auditory processing disorder and listening difficulties in school-age students

    Sakamoto H.

    International Journal of Pediatric Otorhinolaryngology   176   111812   2024.01( ISSN:01655876

  • Tissue responses to everolimus-eluting stents implanted in severely calcified lesions following atherectomy(タイトル和訳中)

    Yamaguchi Tomohiro, Yamazaki Takanori, Yoshida Hisako, Matsumoto Kotaro, Yahiro Ryosuke, Nakao Kazuhiro, Kure Yusuke, Okai Tsukasa, Shimada Takenobu, Otsuka Kenichiro, Izumiya Yasuhiro, Fukuda Daiju

    Cardiovascular Intervention and Therapeutics   39 ( 1 )   34 - 44   2024.01( ISSN:1868-4300

  • Effect of the Xanthine Oxidase Inhibitor, Febuxostat, on WBC Count in Asymptomatic Hyperuricemia: Subanalysis of the Randomized PRIZE Study

    Takeshita Mitsuhide, Tanaka Atsushi, Yoshida Hisako, Nakamura Ikuko, Shibata Yoshisato, Hata Shiro, Kushiyama Akifumi, Okutsu Masaaki, Ishizu Tomoko, Node Koichi

    Journal of Atherosclerosis and Thrombosis   advpub ( 0 )   864 - 875   2024( ISSN:13403478 ( eISSN:18803873

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    <p><b>Aims: </b>The anti-inflammatory effects of the xanthine oxidase inhibitor, febuxostat, a urate-lowering agent, have been reported in animal studies. However, the anti-inflammatory effects of urate-lo wering therapy and its associated cardiovascular protective effects have not been fully determined in actual clinical practice. This study aimed to investigate the effect of febuxostat on white blood cell (WBC) count in patients with asymptomatic hyperuricemia and to assess for potential correlations between changes in WBC count and inflammatory biomarkers and atherosclerosis in this patient population.<b> </b></p><p><b>Methods: </b>This was a <i>post hoc</i> subanalysis of the PRIZE study, a multicenter, prospective, randomized, open-label clinical trial. In the PRIZE study, asymptomatic hyperuricemia patients were randomized to febuxostat group or control group with non-pharmacological therapy and evaluated the effect on vascular. The primary endpoints of this study were the assessment of the time course of WBC count over 24 months and its changes from baseline. Correlations of WBC count with high-sensitivity C-reactive protein (hs-CRP) and mean common carotid artery ( CCA)-IMT were also exploratorily examined in the febuxostat group.<b> </b></p><p><b>Results: </b>A total of 444 patients (febuxostat group, <i>n</i>=223; control group, <i>n</i>=221) with WBC measurements available at baseline and at least one of the follow-up time points of 12 or 24 months, were enrolled. Febuxostat modestly, but significantly, reduced WBC counts at 12 and 24 months compared with the baseline levels (<i>P</i>=0.002 and <i>P</i>=0.026, respectively). Notably, the WBC count in the febuxostat group at 12 and 24 months was significantly lower than that in the control group (<i>P</i>=0.007 and <i>P</i>=0.023, respectively). The changes in WBC count were associated with those of hs-CRP (<i>P</i>=0.038), but not with CCA-IMT (<i>P</i>=0.727).<b> </b></p><p><b>Conclusions: </b>Febuxostat therapy for 24 months modestly, but significantly, decreased WBC count in patients with asymptomatic hyperuricemia. This might potentially reflect a modest anti-inflammatory action of febuxostat in clinical settings.</p>

    DOI: 10.5551/jat.64574

    PubMed

  • Protocol of a pilot randomized clinical trial to evaluate nutritional support and rehabilitation on prevention of skeletal muscle mass loss during neoadjuvant chemotherapy in patients with esophageal cancer.

    Miki Y, Nishi S, Tamura T, Imai T, Nambara M, Fukuoka T, Yoshii M, Toyokawa T, Lee S, Fujii H, Yoshida H, Ikebuchi M, Maeda K

    PloS one   19 ( 4 )   e0302003   2024

  • Rationale and design of an investigator-initiated, multicenter, prospective, placebo-controlled, double-blind, randomized trial to evaluate the effects of finerenone on vascular stiffness and cardiorenal biomarkers in type 2 diabetes and chronic kidney disease (FIVE-STAR)

    Tanaka A.

    Cardiovascular Diabetology   22 ( 1 )   194   2023.12

  • Lack of impact of ipragliflozin on endothelial function in patients with type 2 diabetes: sub-analysis of the PROTECT study

    Kishimoto S.

    Cardiovascular Diabetology   22 ( 1 )   2023.12

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  • Factors associated with carotid intima-media thickness progression in patients with asymptomatic hyperuricemia: insights from the PRIZE study

    Saito Y.

    Scientific Reports   13 ( 1 )   10927   2023.12

  • Clinical effects of a selective urate reabsorption inhibitor dotinurad in patients with hyperuricemia and treated hypertension: a multicenter, prospective, exploratory study (DIANA)

    Tanaka A.

    European Journal of Medical Research   28 ( 1 )   238   2023.12( ISSN:09492321

  • Association of Serum Levels of Cholesterol Absorption and Synthesis Markers with the Presence of Cardiovascular Disease: The CACHE Study CVD Analysis(タイトル和訳中)

    Katsuki Shunsuke, Matoba Tetsuya, Akiyama Yusuke, Yoshida Hiroshi, Kotani Kazuhiko, Fujii Hisako, Harada-Shiba Mariko, Ishibashi Yutaka, Ishida Tatsuro, Ishigaki Yasushi, Kabata Daijiro, Kihara Yasuki, Kurisu Satoshi, Masuda Daisaku, Matsuki Kota, Matsumura Takeshi, Mori Kenta, Nakagami Tomoko, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yoshida Hisako, Tsutsui Hiroyuki, Shoji Tetsuo

    Journal of Atherosclerosis and Thrombosis   30 ( 12 )   1766 - 1777   2023.12( ISSN:1340-3478

  • A Phase I/II Clinical Trial of Intradermal, Controllable Self-Replicating Ribonucleic Acid Vaccine EXG-5003 against SARS-CoV-2

    Koseki T.

    Vaccines   11 ( 12 )   2023.12( ISSN:2076-393X

  • Synergistic effect of proteinuria on dipstick hematuria-related decline in kidney function: The Japan Specific Health Checkups(J-SHC) Study(タイトル和訳中)

    Tasaki Hikari, Eriguchi Masahiro, Yoshida Hisako, Uemura Takayuki, Fukata Fumihiro, Nishimoto Masatoshi, Kosugi Takaaki, Matsui Masaru, Samejima Ken-ichi, Iseki Kunitoshi, Asahi Koichi, Yamagata Kunihiro, Konta Tsuneo, Fujimoto Shouichi, Narita Ichiei, Kasahara Masato, Shibagaki Yugo, Moriyama Toshiki, Kondo Masahide, Watanabe Tsuyoshi, Tsuruya Kazuhiko

    Clinical and Experimental Nephrology   27 ( 12 )   990 - 1000   2023.12( ISSN:1342-1751

  • The Impact of Assisted Reproductive Technology on Umbilical Cord Insertion: Increased Risk of Velamentous Cord Insertion in Singleton Pregnancies Conceived through ICSI

    Fukuda E.

    Medicina (Lithuania)   59 ( 10 )   2023.10( ISSN:1010660X

  • 日本人健康被験者におけるコレステロール吸収・合成マーカーの血清中濃度 CACHE研究HEALTHY解析(Serum Values of Cholesterol Absorption and Synthesis Biomarkers in Japanese Healthy Subjects: The CACHE Study HEALTHY Analysis)

    Ishibashi Yutaka, Yoshida Hiroshi, Kotani Kazuhiko, Akiyama Yusuke, Fujii Hisako, Harada-Shiba Mariko, Ishida Tatsuro, Ishigaki Yasushi, Kabata Daijiro, Kihara Yasuki, Kurisu Satoshi, Masuda Daisaku, Matoba Tetsuya, Matsuki Kota, Matsumura Takeshi, Mori Kenta, Nakagami Tomoko, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yano Shozo, Yoshida Hisako, Shoji Tetsuo

    Journal of Atherosclerosis and Thrombosis   30 ( 10 )   1336 - 1349   2023.10( ISSN:1340-3478

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    健康被験者を対象に、コレステロール合成マーカーであるラトステロール(Latho)と、コレステロール吸収マーカーであるカンペステロール(Campe)およびシトステロール(Sito)の血清中濃度を調べ、それらの基準範囲を求めた。さらに、これらのマーカーと、年齢、性別、BMI、脂質、リポ蛋白コレステロールの血清中濃度との関連を分析した。コレステロール吸収・合成マーカーをガスクロマトグラフィー法で測定するCACHE研究に参加した健康成人2944名から、心血管系疾患の既往のある者、糖尿病、高血圧症、慢性腎臓病、家族性高コレステロール血症、シトステロール血症、現喫煙者、BMIが17kg/m2未満または30kg/m2以上、脂質異常症/高尿酸血症の治療を受けている者を除外した479名(女性285名、男性194名、年齢中央値49歳)を対象とした。性別で層別化した非線形回帰モデルを用いて、各種コレステロール代謝マーカーと、年齢、BMI、HDLコレステロール(HDL-C)、非HDL-Cなどとの関連を調べた。その結果、Latho、Campe、Sitoは正に歪んだ分布を示し、性差がみられた。年齢はLathoと正の相関、Campeと負の相関を示したが、Sitoとは有意な相関を示さなかった。BMIはLathoと正の相関を示したが、CampeやSitoとは有意な相関はみられなかった。HDL-CはCampeおよびSitoと正の相関を示したが、Lathoとは有意な相関を示さなかった。非HDL-Cは三つのマーカーと正の相関を示した。

  • Trace proteinuria detected via dipstick test is associated with kidney function decline and new-onset overt proteinuria: the Japan Specific Health Checkups (J-SHC) Study

    Kosugi T.

    Clinical and Experimental Nephrology   27 ( 10 )   801 - 808   2023.10( ISSN:13421751

  • 家族性高コレステロール血症とコレステロール合成および吸収マーカーの血清中濃度の関連性 CACHE研究FH解析(Association between Familial Hypercholesterolemia and Serum Levels of Cholesterol Synthesis and Absorption Markers: The CACHE Study FH Analysis)

    Matsuki Kota, Harada-Shiba Mariko, Hori Mika, Ogura Masatsune, Akiyama Yusuke, Fujii Hisako, Ishibashi Yutaka, Ishida Tatsuro, Ishigaki Yasushi, Kabata Daijiro, Kihara Yasuki, Kotani Kazuhiko, Kurisu Satoshi, Masuda Daisaku, Matoba Tetsuya, Matsumura Takeshi, Mori Kenta, Nakagami Tomoko, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yoshida Hiroshi, Yoshida Hisako, Shoji Tetsuo

    Journal of Atherosclerosis and Thrombosis   30 ( 9 )   1152 - 1164   2023.09( ISSN:1340-3478

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    脂質低下薬が投与されていない家族性高コレステロール血症(FH)患者と非FH患者でコレステロール代謝の血清マーカーの差異を評価し、血清脂質レベルとの関連性について検討した。日本の13施設で行われたCACHE研究の2944例のうち、脂質低下薬投与や血液透析が行われていないFH患者51例と非FH患者1924例を解析対象とした(CACHE研究FH解析)。潜在的交絡因子で調整後、FH患者は非FH患者に比べてコレステロール吸収マーカーのカンペステロールとシトステロールの血清レベルが有意に高く、コレステロール合成マーカーのラトステロールの血清レベルが非有意に高かった。カンペステロール、シトステロール、ラトステロールの血清レベルは、FH患者における総コレステロールと非線形に関連した。FH患者は非FH患者に比べてカンペステロール/ラトステロール比およびシトステロール/ラトステロール比が有意に高値であった。FH患者では、コレステロール合成に対してコレステロール吸収が増大していることが示唆された。

  • 糖尿病と血清ラトステロールおよびカンペステロール濃度との関係 CACHE研究のDM分析(Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis)

    Matsumura Takeshi, Ishigaki Yasushi, Nakagami Tomoko, Akiyama Yusuke, Ishibashi Yutaka, Ishida Tatsuro, Fujii Hisako, Harada-Shiba Mariko, Kabata Daijiro, Kihara Yasuki, Kotani Kazuhiko, Kurisu Satoshi, Masuda Daisaku, Matoba Tetsuya, Matsuki Kota, Mori Kenta, Nakazato Masamitsu, Taniuchi Satsuki, Ueno Hiroaki, Yamashita Shizuya, Yoshida Hiroshi, Yoshida Hisako, Shoji Tetsuo

    Journal of Atherosclerosis and Thrombosis   30 ( 7 )   735 - 753   2023.07( ISSN:1340-3478

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    動脈硬化性疾患の高リスク患者2182名を対象に、糖尿病(DM)とコレステロール代謝マーカーであるラトステロール(Latho)およびカンペステロール(Campe)の血清中濃度との関連について検討した。対象は動脈硬化性疾患高リスク病態におけるコレステロール吸収・合成マーカー(CACHE研究)に登録された患者で、コレステロール合成マーカー(Latho)と吸収マーカー(Campe)を測定した。患者を糖尿病を有するDM群830名(女性33.7%、中央値63歳)と非DM群1352名(女性47.3%、中央値56歳)の2群に分類した。血清Latho濃度に有意な群間差はなかった。血清Campe濃度およびCampe/Latho比はDM群の方が有意に低かった(いずれもP<0.001)。多重ロジスティック回帰分析で年齢、性別、心血管疾患、高血圧症、脂質異常症、慢性腎臓病の既往、喫煙歴、スタチン使用で調整し、制限付き三次スプライン回帰モデルを適用した。その結果、CampeとCampe/Latho比は血糖値およびHbA1cと逆U字曲線的関係を呈した。LathoはHbA1cとU字関係を呈したが、血糖値とは逆U字関係を呈した。

  • Effect of febuxostat on the level of malondialdehyde-modified low-density lipoprotein, an oxidative stress marker: A subanalysis of the PRIZE study

    Teragawa H.

    Clinical Cardiology   46 ( 6 )   698 - 706   2023.06( ISSN:01609289

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  • A favorable impression of vaccination leads to a better vaccination rate for the human papillomavirus vaccine: A Japanese questionnaire survey investigation

    Jwa S.

    Vaccine: X   13   100254   2023.04

  • 身長低下は腎機能低下と関連する 日本特定健診(J-SHC)研究(Height loss is associated with decreased kidney function: The Japan Specific Health Checkups(J-SHC) Study)

    Kosugi Takaaki, Eriguchi Masahiro, Yoshida Hisako, Uemura Takayuki, Tasaki Hikari, Fukata Fumihiro, Nishimoto Masatoshi, Matsui Masaru, Samejima Ken-ichi, Iseki Kunitoshi, Fujimoto Shouichi, Konta Tsuneo, Moriyama Toshiki, Yamagata Kunihiro, Narita Ichiei, Kasahara Masato, Shibagaki Yugo, Kondo Masahide, Asahi Koichi, Watanabe Tsuyoshi, Tsuruya Kazuhiko

    Geriatrics & Gerontology International   23 ( 4 )   282 - 288   2023.04( ISSN:1444-1586

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    日本特定健診データ(2008~2014年)を用いた縦断研究を実施し、身長低下と腎臓転帰との関連について検討した。最初の3回の受診(1~3回目)を身長減少の推定に用い、3回目から最終受診までのデータを用いて腎臓転帰を評価した。各受診者の年間身長変化率の5分位により、Q1~5(Q4を基準、Q1の身長低下率が最も急)に分けて検討した。計187682例を解析対象とした。身長変化率中央値は-0.11cm/年であった。Cox回帰分析を用いて、身長変化とベースラインからの血清クレアチニン値1.5倍上昇との関連について検討した。その結果、Q4と比較してQ1の血清クレアチニン値1.5倍上昇の調整ハザード比は1.45であった。Q1の推算糸球体濾過率低下はQ4と比較して有意に高かった(-0.92mL/分/1.73m2/年対-1.25mL/分/1.73m2/年、交互作用P<0.001)。以上から、身長低下は腎機能の急速な低下と関連していることが示された。

  • Effect of ipragliflozin on carotid intima-media thickness in patients with type 2 diabetes: a multicenter, randomized, controlled trial

    Tanaka A.

    European heart journal. Cardiovascular pharmacotherapy   9 ( 2 )   165 - 172   2023.02( ISSN:2055-6837

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  • More rapid progression of brain atrophy in patients on peritoneal dialysis compared with hemodialysis: The VCOHP Study

    Tsuruya K.

    Hypertension Research   47 ( 4 )   887 - 897   2023( ISSN:09169636

  • Impact of cystatin C-derived glomerular filtration rate in patients undergoing transcatheter aortic valve implantation

    Kure Y.

    Frontiers in Cardiovascular Medicine   10   1035736   2023( ISSN:2297-055X

  • Survey on the Impact of the COVID-19 Pandemic on Patients with Parkinson’s Disease and Their Caregivers in Japan

    Hattori N.

    Patient Preference and Adherence   17   1221 - 1235   2023( ISSN:1177-889X

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  • Association of Kidney Function with Serum Levels of Cholesterol Absorption and Synthesis Markers: The CACHE Study CKD Analysis.

    Shoji T, Akiyama Y, Fujii H, Harada-Shiba M, Ishibashi Y, Ishida T, Ishigaki Y, Kabata D, Kihara Y, Kotani K, Kurisu S, Masuda D, Matoba T, Matsuki K, Matsumura T, Mori K, Nakagami T, Nakazato M, Taniuchi S, Ueno H, Yamashita S, Yoshida H, Yoshida H

    Journal of atherosclerosis and thrombosis   29 ( 12 )   1835 - 1848   2022.12( ISSN:1340-3478

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  • 公益社団法人日本麻酔科学会第69回学術集会講演特集号 学術委員会:学会賞記念講演 Recruitment maneuverによる血行動態変化率は分離肺換気下における輸液反応性の指標として有効である

    木村 文, 末廣 浩一, 重里 尚, 藤本 陽平, 吉田 寿子, 田中 克明, 森 隆, 西川 精宣

    麻酔   71 ( 13 )   S171 - S178   2022.11( ISSN:00214892

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  • Relationship between Cardiac Acoustic Biomarkers and Pulmonary Artery Pressure in Patients with Heart Failure

    Kaneko T.

    Journal of Clinical Medicine   11 ( 21 )   2022.11( ISSN:2077-0383

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  • Nutritional Disorder Evaluated by the Geriatric Nutritional Risk Index Predicts Death After Hospitalization for Infection in Patients Undergoing Maintenance Hemodialysis.

    Machiba Y, Mori K, Shoji T, Nagata Y, Uedono H, Nakatani S, Ochi A, Tsuda A, Morioka T, Yoshida H, Tsujimoto Y, Emoto M

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   32 ( 6 )   751 - 757   2022.11( ISSN:1051-2276

  • 特集 腎疾患における臨床研究の進歩 【臨床研究の最新手法】 ブートストラップ法

    吉田 寿子

    腎と透析   93 ( 3 )   329 - 334   2022.09( ISSN:03852156

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  • Impact of febuxostat on visit-to-visit blood pressure variability: insights from the randomised PRIZE Study

    Saito Y.

    RMD Open   8 ( 2 )   2022.09

  • Three-dimensional transesophageal echocardiographic morphological evaluation of the tricuspid valve.

    Kawase T, Takahashi Y, Ito A, Yoshida H, Sumii Y, Nishiya K, Kishimoto N, Yamane K, Sakon Y, Morisaki A, Fujii H, Shibata T

    Interactive cardiovascular and thoracic surgery   35 ( 2 )   2022.07( ISSN:1569-9293

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  • Antithrombotics increase bleeding after endoscopic submucosal dissection for gastric cancer: Nationwide propensity score analysis.

    Nagami Y, Hatta W, Tsuji Y, Yoshio T, Kakushima N, Hoteya S, Tsuji S, Fukunaga S, Hikichi T, Kobayashi M, Morita Y, Sumiyoshi T, Iguchi M, Tomida H, Inoue T, Mikami T, Hasatani K, Nishikawa J, Matsumura T, Nebiki H, Nakamatsu D, Ohnita K, Suzuki H, Ueyama H, Hayashi Y, Yoshida H, Fujishiro M, Masamune A, Fujiwara Y

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society   34 ( 5 )   974 - 983   2022.07( ISSN:0915-5635

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  • Possible role of insulin resistance in activation of plasma xanthine oxidoreductase in health check-up examinees.

    Kurajoh M, Fukumoto S, Akari S, Murase T, Nakamura T, Takahashi K, Yoshida H, Nakatani S, Tsuda A, Morioka T, Mori K, Imanishi Y, Hirata K, Emoto M

    Scientific reports   12 ( 1 )   10281   2022.06

  • 急性顔面神経麻痺治療のためのメチルプレドニゾロンパルス静注療法のコルチコステロイド通常投与との効果の比較 傾向スコア解析(Comparing the Effects of Intravenous Methylpredonisolone Pulse Therapy with the Conventional dose of Corticosteroids for the Treatment of Acute Facial Nerve Palsy: A Propensity Score Analysis)

    Oishi Masahiro, Kouda Yuki, Amatsu Hisao, Yoshida Hisako, Shintani Ayumi, Sunami Kishiko

    Osaka City Medical Journal   68 ( 1 )   1 - 10   2022.06( ISSN:0030-6096

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    急性顔面神経麻痺治療におけるメチルプレドニゾロンパルス静注療法の有効性を評価するために、コルチコステロイド通常投与と比較する後ろ向き観察研究を行った。急性顔面神経麻痺の発症後7日以内に治療を始めた患者を対象とした。74例の顔面神経麻痺のデータを分析したが、48例はメチルプレドニゾロンパルス静注療法で、26例はコルチコステロイド通常投与で治療した。メチルプレドニゾロンパルス静注療法とコルチコステロイド通常投与による回復率は70.8%と84.6%で、治療期間の中央値は61日と30日であった。治療期間に関するKaplan-Meier曲線では両群間で有意差があり、コルチコステロイド通常投与群で治療期間が短縮した。以上より、メチルプレドニゾロンパルス静注療法がコルチコステロイド通常投与よりも優れていることを示す結果は得られなかった。

  • Association between serum urate level and carotid atherosclerosis: an insight from a post hoc analysis of the PRIZE randomised clinical trial.

    Tanaka A, Toyoda S, Kato T, Yoshida H, Hamasaki S, Watarai M, Ishizu T, Ueda S, Inoue T, Node K, PRIZE study investigators

    RMD open   8 ( 1 )   2022.04

  • Differential effect of a xanthine oxidase inhibitor on arterial stiffness and carotid atherosclerosis: a subanalysis of the PRIZE study.

    Shiina K, Tomiyama H, Tanaka A, Yoshida H, Eguchi K, Kario K, Kato T, Teragawa H, Toyoda S, Ohishi M, Fukumoto Y, Takase B, Ishizu T, Node K, PRIZE Study Investigators

    Hypertension research : official journal of the Japanese Society of Hypertension   45 ( 4 )   602 - 611   2022.04( ISSN:0916-9636

  • Malnutrition-Inflammation Complex Syndrome and Bone Fractures and Cardiovascular Disease Events in Patients Undergoing Hemodialysis: The Q-Cohort Study.

    Yamada S, Arase H, Yoshida H, Kitamura H, Tokumoto M, Taniguchi M, Hirakata H, Tsuruya K, Nakano T, Kitazono T

    Kidney medicine   4 ( 3 )   100408   2022.03

  • Computed tomography to identify risk factors for left circumflex artery injury during mitral surgery.

    Kishimoto N, Takahashi Y, Fujii H, Sakon Y, Izuta S, Kitada R, Morisaki A, Yoshida H, Ehara S, Shibata T

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery   61 ( 3 )   675 - 683   2022.02( ISSN:1010-7940

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  • Angioscopic Ulcerated Plaques in the Femoropopliteal Artery Associated with Impaired Infrapopliteal Runoff.

    Yamaguchi T, Yamazaki T, Yoshida H, Hayashi O, Yahiro R, Nakao K, Okai T, Ehara S, Izumiya Y, Yoshiyama M

    Journal of vascular and interventional radiology : JVIR   33 ( 2 )   97 - 103.e1   2022.02( ISSN:1051-0443

  • Superiority of laparoscopic liver resection to open liver resection in obese individuals with hepatocellular carcinoma: A retrospective study.

    Ishihara A, Tanaka S, Shinkawa H, Yoshida H, Takemura S, Amano R, Kimura K, Ohira G, Nishio K, Kubo S

    Annals of gastroenterological surgery   6 ( 1 )   135 - 148   2022.01

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  • Real-world data on NGS using the Oncomine DxTT for detecting genetic alterations in non-small-cell lung cancer: WJOG13019L.

    Sakata S, Otsubo K, Yoshida H, Ito K, Nakamura A, Teraoka S, Matsumoto N, Shiraishi Y, Haratani K, Tamiya M, Ikeda S, Miura S, Tanizaki J, Omori S, Yoshioka H, Hata A, Yamamoto N, Nakagawa K

    Cancer science   113 ( 1 )   221 - 228   2022.01( ISSN:1347-9032

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  • Effect of febuxostat on left ventricular diastolic function in patients with asymptomatic hyperuricemia: a sub analysis of the PRIZE Study.

    Kusunose K, Yoshida H, Tanaka A, Teragawa H, Akasaki Y, Fukumoto Y, Eguchi K, Kamiya H, Kario K, Yamada H, Sata M, Node K, PRIZE Study Investigators

    Hypertension research : official journal of the Japanese Society of Hypertension   45 ( 1 )   106 - 115   2022.01( ISSN:0916-9636

  • Long-Term Effect of Febuxostat on Endothelial Function in Patients With Asymptomatic Hyperuricemia: A Sub-Analysis of the PRIZE Study.

    Maruhashi T, Higashi Y, Yoshida H, Tanaka A, Eguchi K, Tomiyama H, Kario K, Kato T, Oda N, Tahara N, Oguri M, Watada H, Node K

    Frontiers in cardiovascular medicine   9   882821   2022( ISSN:2297-055X

  • Impact of self-reported walking habit on slower decline in renal function among the general population in a longitudinal study: the Japan Specific Health Checkups (J-SHC) Study.

    Nishimoto M, Murashima M, Yoshida H, Eriguchi M, Tasaki H, Fukata F, Kosugi T, Matsui M, Samejima KI, Iseki K, Asahi K, Yamagata K, Fujimoto S, Konta T, Narita I, Moriyama T, Kasahara M, Shibagaki Y, Kondo M, Watanabe T, Tsuruya K, Japan Specific Health Checkups (J-SHC) Study Group

    Journal of nephrology   34 ( 6 )   1845 - 1853   2021.12( ISSN:1121-8428

  • Association between chronic kidney disease and new-onset dyslipidemia: The Japan Specific Health Checkups (J-SHC) study.

    Kosugi T, Eriguchi M, Yoshida H, Tasaki H, Fukata F, Nishimoto M, Matsui M, Samejima KI, Iseki K, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kasahara M, Shibagaki Y, Kondo M, Asahi K, Watanabe T, Tsuruya K, Japan Specific Health Checkups (J-SHC) Study Group

    Atherosclerosis   332   24 - 32   2021.09( ISSN:0021-9150

  • Trace proteinuria as a risk factor for cancer death in a general population.

    Matsui M, Tsuruya K, Yoshida H, Iseki K, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kasahara M, Shibagaki Y, Kondo M, Asahi K, Watanabe T

    Scientific reports   11 ( 1 )   16890   2021.08

  • Hemodynamic Changes via the Lung Recruitment Maneuver Can Predict Fluid Responsiveness in Stroke Volume and Arterial Pressure During One-Lung Ventilation.

    Kimura A, Suehiro K, Juri T, Fujimoto Y, Yoshida H, Tanaka K, Mori T, Nishikawa K

    Anesthesia and analgesia   133 ( 1 )   44 - 52   2021.07( ISSN:0003-2999

  • Comparative Effects of Etelcalcetide and Maxacalcitol on Serum Calcification Propensity in Secondary Hyperparathyroidism: A Randomized Clinical Trial.

    Shoji T, Nakatani S, Kabata D, Mori K, Shintani A, Yoshida H, Takahashi K, Ota K, Fujii H, Ueda S, Nishi S, Nakatani T, Yoshiyama M, Goto K, Hamada T, Imanishi M, Ishimura E, Kagitani S, Kato Y, Kumeda Y, Maekawa K, Matsumura T, Nagayama H, Obi Y, Ohno Y, Sai Y, Sakurai M, Sasaki S, Shidara K, Shoji S, Tsujimoto Y, Yamakawa K, Yasuda H, Yodoi S, Inaba M, Emoto M

    Clinical journal of the American Society of Nephrology : CJASN   16 ( 4 )   599 - 612   2021.04( ISSN:1555-9041

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  • Uric acid shown to contribute to increased oxidative stress level independent of xanthine oxidoreductase activity in MedCity21 health examination registry.

    Kurajoh M, Fukumoto S, Yoshida S, Akari S, Murase T, Nakamura T, Ishii H, Yoshida H, Nagata Y, Morioka T, Mori K, Imanishi Y, Hirata K, Emoto M

    Scientific reports   11 ( 1 )   7378   2021.04

  • 非弁膜性心房細動患者を対象とした直接作用型経口抗凝固薬の服薬アドヒアランスの多施設共同大規模実態調査

    三浦 誠, 翁長 真一郎, 杉山 哲大, 尾濱 直子, 宮里 弥篤, 合田 貴史, 國分 千代, 中村 美樹, 笹田 みどり, 鈴木 正論, 本田 憲一, 花村 菜月, 濱武 久美子, 秋山 裕史, 筒井 由佳, 荒木 哲也, 伊花 和宏, 新沼 芳文, 森島 義行, 長田 茂幸, 瀧田 厚, 木村 哲也, 吉田 寿子, 新谷 歩, 関 利一

    医療薬学   47 ( 3 )   132 - 144   2021.03( ISSN:1346-342X

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    直接作用型経口抗凝固薬(DOAC)を服用中の非弁膜症性心房細動(NVAF)患者にみられる服薬アドヒアランスの実態を調査した。16施設の共同研究施設を受診した外来診療中のNVAF患者817名を対象とした。DOAC服薬率は97.49±6.728%であった。服薬不遵守に関連する因子を、多変量2値ロジスティック回帰モデルを用いて解析した。その結果、服薬不遵守定義1(服薬率90%未満および処方日数到達日の翌日までに来院しなかった対象者)では75歳未満、薬識レベル低値の二つが服薬不遵守に有意に関連する因子であった。また、男性は服薬不遵守に関連する傾向がみられた。服薬不遵守定義2(残薬が多いために持参しなかった対象者)ではかかりつけ薬局/薬剤師がないことと薬識レベルが低いことが服薬不遵守に有意に関連する因子であった。また、院内処方および病識レベルが低いことが関連する傾向が認められた。

  • Continuous warfarin administration versus heparin bridging therapy in post colorectal polypectomy haemorrhage: a study protocol for a multicentre randomised controlled trial (WHICH study).

    Nagami Y, Sakai T, Yamamura M, Nakatani M, Katsuno T, Suekane T, Uno H, Minamino H, Okuyama M, Okamoto J, Kumamoto M, Noguchi A, Yamamori K, Takaishi O, Ochi M, Miyazaki T, Tsuji S, Ikehara H, Kawaguchi K, Hayashi T, Mannami T, Kakimoto K, Naito Y, Hashimoto S, Li Z, Komeda Y, Kishino T, Yamamoto Y, Iguchi M, Akamatsu T, Horii T, Miura K, Yamashina T, Sugihara Y, Watanabe N, Kiyotoki S, Fujii R, Murata M, Ono S, Narasaka T, Kitamura S, Kono M, Kato M, Kawaratani H, Tanaka K, Yaoita T, Yamaguchi S, Abe K, Kawamura T, Kinoshita Y, Imai K, Fujinami H, Yada T, Miyamoto H, Yoshida H, Fujiwara Y

    Trials   22 ( 1 )   33   2021.01

  • Anorexia nervosa restricting type has increased in severity over three decades: Japanese clinical samples from 1988 to 2018.

    Harada T, Yamauchi T, Miyawaki D, Miyamoto S, Yoshida H, Nishimoto K, Matsuzuka T, Honda M, Inoue K

    The International journal of eating disorders   54 ( 1 )   54 - 58   2021.01( ISSN:0276-3478

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  • Stronger Effect of Azilsartan on Reduction of Proteinuria Compared to Candesartan in Patients with CKD: A Randomized Crossover Trial.

    Suehiro T, Tsuruya K, Yoshida H, Tsujikawa H, Yamada S, Tanaka S, Tsuchimoto A, Eriguchi M, Fujisaki K, Torisu K, Nakano T, Kitazono T

    Kidney & blood pressure research   46 ( 2 )   173 - 184   2021( ISSN:1420-4096

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  • 腹膜透析施行患者における自動腹膜透析の長所と短所の認識の差 コンジョイント分析(Difference in perception of advantages and disadvantages of automated peritoneal dialysis for patients undergoing peritoneal dialysis: a conjoint analysis)

    Yoshida Hisako, Tsuruya Kazuhiko

    Renal Replacement Therapy   7   1 of 7 - 7 of 7   2021

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    腹膜透析(PD)を受けている患者が自動PD(APD)の長所と短所をどのように認識しているか検討した。PD施行患者32例(男性21例、女性11例、平均57±13歳)を対象に、適正透析、腹圧、腹膜炎リスク、バッグ交換頻度、デバイスサイズ、手技といったPDの6つの特性に基づいてシミュレーションを実施させた。PDの平均期間は24ヵ月で、17例がAPD、15例がCAPDを受けていた。PDの平均期間と透析液の容量はAPD群の方がCAPD群より有意に高値を示し、腹膜炎の既往に群間差はみられなかった。検討の結果、APDの長所・短所の認識に最も影響していたのはバッグ交換頻度であり、APDデバイスサイズと腹膜炎リスクがこれに続き、PD補助デバイスの操作方法の影響は少なかった。また、APD施行群ではバッグ交換頻度が最も重要視され、CAPD群ではAPDデバイスサイズを重視する傾向が強かった。腹膜炎の病歴、透析期間、紫外線連結デバイスの使用、透析液の容量を補正後も、バッグ交換頻度とデバイスサイズが重視される結果は維持されていた。

  • Effects of Polymorphisms in the Serotonin Transporter Promoter-Linked Polymorphic Region on Postthoracotomy Pain Severity.

    Kimura A, Yamasaki H, Ishii H, Yoshida H, Shimizu M, Mori T

    Journal of pain research   14   1389 - 1397   2021( ISSN:1178-7090

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  • Patient and Physician Perspectives of Depressive Symptoms and Expectations for Treatment Outcome: Results from a Web-Based Survey.

    Ishigooka J, Hoshino T, Imai T, Yoshida H, Ono M, Ota M, Moriguchi Y, Fujikawa K, Shintani A, Fernandez JL

    Neuropsychiatric disease and treatment   17   2915 - 2924   2021( ISSN:1176-6328

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  • Placebo-Controlled, Double-Blind Study of Empagliflozin (EMPA) and Implantable Cardioverter-Defibrillator (EMPA-ICD) in Patients with Type 2 Diabetes (T2DM): Rationale and Design.

    Fujiki S, Iijima K, Okabe M, Niwano S, Tsujita K, Naito S, Ando K, Kusano K, Kato R, Nitta J, Miura T, Mitsuhashi T, Kario K, Kondo Y, Ieda M, Hagiwara N, Murohara T, Takahashi K, Tomita H, Takeishi Y, Anzai T, Shimizu W, Watanabe M, Morino Y, Kato T, Tada H, Nakagawa Y, Yano M, Maemura K, Kimura T, Yoshida H, Ota K, Tanaka T, Kitamura N, Node K, Aizawa Y, Shimizu I, Izumi D, Ozaki K, Minamino T, EMPA-ICD investigators

    Diabetes therapy : research, treatment and education of diabetes and related disorders   11 ( 11 )   2739 - 2755   2020.11( ISSN:1869-6953

  • Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD).

    Ninomiya T, Nakaji S, Maeda T, Yamada M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ohara T, Hata J, Kokubo Y, Uchida K, Taki Y, Kumagai S, Yonemoto K, Yoshida H, Muto K, Momozawa Y, Akiyama M, Kubo M, Ikeda M, Kanba S, Kiyohara Y, JPSFC-AD Study Group

    Environmental health and preventive medicine   25 ( 1 )   64   2020.10( ISSN:1342-078X

  • 心房細動発症または診断からカテーテルアブレーション治療までの期間と治療効果に関する検討 プライマリケア医の役割

    松本 善太郎, 小堀 敦志, 熊谷 浩一郎, 遠山 英子, 吉田 寿子, 新谷 歩, 佐々木 康博, 古川 裕

    心電図   40 ( 3 )   158 - 166   2020.10( ISSN:0285-1660

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    心房細動(atrial fibrillation:AF)に対するカテーテルアブレーションは、その高い治療効果から広く施行されるようになってきたが、術後の再発は課題のひとつである。その治療効果について、施行施設からの報告は多い。しかし、プライマリケアを行う医療機関からの、本邦におけるAFに対するカテーテルアブレーションの早期実施効果を検討した報告は少ない。今回われわれは、AFの発症または診断からカテーテルアブレーション治療までの期間による治療効果を検討した。当院を受診したAF患者のうちカテーテルアブレーションを施行した発作性AF82例と持続性AF15例を対象とした。カテーテルアブレーション術後3ヵ月以後に30秒以上持続する心房性不整脈を再発と定義した。年齢およびCHADS2スコアにかかわらず、AF発症または診断からカテーテルアブレーション治療実施までの期間が短くなるほど初回治療後の洞調律維持率が上昇した。AFは進行性疾患であり、AFの発症および診断から、抗凝固薬と効果の不確定な抗不整脈薬のみで漫然と経過観察するのではなく、できるだけ早期にカテーテルアブレーションを実施するため、プライマリケア医の早い判断で施行可能な施設に紹介することが重要であると考えられた。(著者抄録)

  • Venue of catheter insertion does not significantly impact the event of central line-associated bloodstream infection in patients with haematological diseases.

    Kitamura H, Kubota Y, Komukai S, Yoshida H, Kaneko Y, Mihara Y, Nagasawa Z, Kawaguchi A, Aoki Y, Kimura S

    Infection prevention in practice   2 ( 2 )   100050   2020.06

  • Increased Risk of Infection-Related and All-Cause Death in Hypercalcemic Patients Receiving Hemodialysis: The Q-Cohort Study.

    Yamada S, Arase H, Tokumoto M, Taniguchi M, Yoshida H, Nakano T, Tsuruya K, Kitazono T

    Scientific reports   10 ( 1 )   6327   2020.04

  • Association of plasma xanthine oxidoreductase activity with blood pressure affected by oxidative stress level: MedCity21 health examination registry.

    Yoshida S, Kurajoh M, Fukumoto S, Murase T, Nakamura T, Yoshida H, Hirata K, Inaba M, Emoto M

    Scientific reports   10 ( 1 )   4437   2020.03

  • Lower Serum Albumin Level Is Associated With an Increased Risk for Loss of Residual Kidney Function in Patients Receiving Peritoneal Dialysis.

    Yamada S, Kawai Y, Tsuneyoshi S, Tsujikawa H, Arase H, Yoshida H, Tsuruya K, Nakano T, Kitazono T

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   24 ( 1 )   72 - 80   2020.02( ISSN:1744-9979

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  • Advanced glycation end products are associated with immature angiogenesis and peritoneal dysfunction in patients on peritoneal dialysis.

    Nakano T, Mizumasa T, Kuroki Y, Eriguchi M, Yoshida H, Taniguchi M, Masutani K, Tsuruya K, Kitazono T

    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis   40 ( 1 )   67 - 75   2020.01( ISSN:0896-8608

  • The intervention by an antimicrobial stewardship team can improve clinical and microbiological outcomes of resistant gram-negative bacteria.

    Yamada K, Imoto W, Yamairi K, Shibata W, Namikawa H, Yoshii N, Fujimoto H, Nakaie K, Okada Y, Fujita A, Kawaguchi H, Shinoda Y, Nakamura Y, Kaneko Y, Yoshida H, Kakeya H

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   25 ( 12 )   1001 - 1006   2019.12( ISSN:1341-321X

  • Colorectal endoscopic mucosal resection with submucosal injection of epinephrine versus hypertonic saline in patients taking antithrombotic agents: propensity-score-matching analysis.

    Yamaguchi D, Yoshida H, Ikeda K, Takeuchi Y, Yamashita S, Jubashi A, Yukimoto T, Takeshita E, Yoshioka W, Fukuda H, Tominaga N, Tsuruoka N, Morisaki T, Ario K, Tsunada S, Fujimoto K

    BMC gastroenterology   19 ( 1 )   192   2019.11

  • Effect of Empagliflozin on Endothelial Function in Patients With Type 2 Diabetes and Cardiovascular Disease: Results from the Multicenter, Randomized, Placebo-Controlled, Double-Blind EMBLEM Trial.

    Tanaka A, Shimabukuro M, Machii N, Teragawa H, Okada Y, Shima KR, Takamura T, Taguchi I, Hisauchi I, Toyoda S, Matsuzawa Y, Tomiyama H, Yamaoka-Tojo M, Yoshida H, Sato Y, Ikehara Y, Ueda S, Higashi Y, Node K, EMBLEM Investigators

    Diabetes care   42 ( 10 )   e159 - e161   2019.10( ISSN:0149-5992

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  • Association of B-Type Natriuretic Peptide Level With Residual Kidney Function in Incident Peritoneal Dialysis Patients.

    Kawai Y, Tanaka S, Yoshida H, Hara M, Tsujikawa H, Tsuruya K, Kitazono T

    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis   39 ( 2 )   147 - 154   2019.03( ISSN:0896-8608

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  • Shorter Relapse-Free Period after Leukocyte Removal Therapy in Younger than Older Patients with Ulcerative Colitis.

    Yamasaki S, Sakata Y, Yoshida H, Shirai S, Tanaka Y, Nakano R, Yukimoto T, Tsuruoka N, Shimoda R, Fukuda M, Miyazono M, Ikeda Y, Iwakiri R, Anzai K, Fujimoto K

    Digestion   100 ( 4 )   247 - 253   2019( ISSN:0012-2823

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  • Sitagliptin on carotid intima-media thickness in type 2 diabetes patients receiving primary or secondary prevention of cardiovascular disease: A subgroup analysis of the PROLOGUE study.

    Tanaka A, Yoshida H, Nanasato M, Oyama JI, Ishizu T, Ajioka M, Ishiki R, Saito M, Shibata Y, Kaku K, Maemura K, Higashi Y, Inoue T, Murohara T, Node K

    International journal of cardiology   271   331 - 335   2018.11( ISSN:0167-5273

  • Comparison of the effects of linagliptin and voglibose on endothelial function in patients with type 2 diabetes and coronary artery disease: a prospective, randomized, pilot study (EFFORT).

    Koyama T, Tanaka A, Yoshida H, Oyama JI, Toyoda S, Sakuma M, Inoue T, Otsuka Y, Node K

    Heart and vessels   33 ( 8 )   958 - 964   2018.08( ISSN:0910-8327

  • Modified creatinine index and risk for cardiovascular events and all-cause mortality in patients undergoing hemodialysis: The Q-Cohort study.

    Arase H, Yamada S, Yotsueda R, Taniguchi M, Yoshida H, Tokumoto M, Nakano T, Tsuruya K, Kitazono T

    Atherosclerosis   275   115 - 123   2018.08( ISSN:0021-9150

  • Use of phosphate-binders and risk of infection-related and all-cause mortality in patients undergoing hemodialysis: The Q-Cohort Study.

    Yamada S, Tokumoto M, Taniguchi M, Yoshida H, Arase H, Tatsumoto N, Hirakata H, Kitazono T, Tsuruya K

    Scientific reports   8 ( 1 )   11387   2018.07

  • The utility of a network-based clustering method for dimension reduction of imaging and non-imaging biomarkers predictive of Alzheimer's disease.

    Yoshida H, Kawaguchi A, Yamashita F, Tsuruya K

    Scientific reports   8 ( 1 )   2807   2018.02

  • Prevalence of pruritus in patients with chronic liver disease: A multicenter study.

    Oeda S, Takahashi H, Yoshida H, Ogawa Y, Imajo K, Yoneda M, Koshiyama Y, Ono M, Hyogo H, Kawaguchi T, Fujii H, Nishino K, Sumida Y, Tanaka S, Kawanaka M, Torimura T, Saibara T, Kawaguchi A, Nakajima A, Eguchi Y, Japan Study Group of Nonalcoholic Fatty Liver Disease (JSG-NAFLD)

    Hepatology research : the official journal of the Japan Society of Hepatology   48 ( 3 )   E252 - E262   2018.02( ISSN:1386-6346

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  • New insertion method of transnasal ileus tube for small bowel obstruction: Anterior balloon method.

    Yamaguchi D, Ikeda K, Takeuchi Y, Kinoshita R, Higuchi T, Fukuda H, Tominaga N, Morisaki T, Ario K, Tsunada S, Yoshida H, Fujimoto K

    PloS one   13 ( 11 )   e0207099   2018

  • Association of Hypertriglyceridemia With the Incidence and Progression of Chronic Kidney Disease and Modification of the Association by Daily Alcohol Consumption.

    Tsuruya K, Yoshida H, Nagata M, Kitazono T, Iseki K, Iseki C, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kimura K, Kondo M, Asahi K, Ohashi Y, Watanabe T

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation   27 ( 6 )   381 - 394   2017.11( ISSN:1051-2276

  • Modified Creatinine Index and the Risk of Bone Fracture in Patients Undergoing Hemodialysis: The Q-Cohort Study.

    Yamada S, Taniguchi M, Tokumoto M, Yoshitomi R, Yoshida H, Tatsumoto N, Hirakata H, Fujimi S, Kitazono T, Tsuruya K

    American journal of kidney diseases : the official journal of the National Kidney Foundation   70 ( 2 )   270 - 280   2017.08( ISSN:0272-6386

  • N-terminal pro-brain natriuretic peptide and associated factors in the general working population: a baseline survey of the Uranosaki cohort study.

    Tanaka A, Yoshida H, Kawaguchi A, Oyama JI, Kotooka N, Toyoda S, Inoue T, Natsuaki M, Node K

    Scientific reports   7 ( 1 )   5810   2017.07

  • The Fukuoka Kidney disease Registry (FKR) Study: design and methods.

    Tanaka S, Ninomiya T, Fujisaki K, Yoshida H, Nagata M, Masutani K, Tokumoto M, Mitsuiki K, Hirakata H, Fujimi S, Kiyohara Y, Kitazono T, Tsuruya K, Fukuoka Kidney disease Registry (FKR) Study Collaboration Group

    Clinical and experimental nephrology   21 ( 3 )   465 - 473   2017.06( ISSN:1342-1751

  • Effect of sitagliptin on the echocardiographic parameters of left ventricular diastolic function in patients with type 2 diabetes: a subgroup analysis of the PROLOGUE study.

    Yamada H, Tanaka A, Kusunose K, Amano R, Matsuhisa M, Daida H, Ito M, Tsutsui H, Nanasato M, Kamiya H, Bando YK, Odawara M, Yoshida H, Murohara T, Sata M, Node K, PROLOGUE Study Investigators

    Cardiovascular diabetology   16 ( 1 )   63   2017.05

  • Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial.

    Tanaka A, Shimabukuro M, Okada Y, Taguchi I, Yamaoka-Tojo M, Tomiyama H, Teragawa H, Sugiyama S, Yoshida H, Sato Y, Kawaguchi A, Ikehara Y, Machii N, Maruhashi T, Shima KR, Takamura T, Matsuzawa Y, Kimura K, Sakuma M, Oyama JI, Inoue T, Higashi Y, Ueda S, Node K, EMBLEM Trial Investigators

    Cardiovascular diabetology   16 ( 1 )   48   2017.04

  • Total Phosphate Elimination is Negatively Associated With Increased Serum Fibroblast Growth Factor 23 Levels in Patients who Undergo Peritoneal Dialysis.

    Yamada S, Tsuruya K, Tokumoto M, Yoshida H, Tatsumoto N, Ooboshi H, Kitazono T

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   21 ( 1 )   71 - 78   2017.02( ISSN:1744-9979

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  • Factors Associated with the Serum Myostatin Level in Patients Undergoing Peritoneal Dialysis: Potential Effects of Skeletal Muscle Mass and Vitamin D Receptor Activator Use.

    Yamada S, Tsuruya K, Yoshida H, Tokumoto M, Ueki K, Ooboshi H, Kitazono T

    Calcified tissue international   99 ( 1 )   13 - 22   2016.07( ISSN:0171-967X

  • Extended Swan-Neck Catheter With Upper Abdominal Exit-Site Reduces Peritoneal Dialysis-Related Infections.

    Eriguchi M, Tsuruya K, Yoshida H, Haruyama N, Tanaka S, Tsuchimoto A, Fujisaki K, Torisu K, Masutani K, Kitazono T

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   20 ( 2 )   158 - 64   2016.04( ISSN:1744-9979

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  • Erythropoiesis-stimulating agent slows the progression of chronic kidney disease: a possibility of a direct action of erythropoietin.

    Tsuruya K, Yoshida H, Suehiro T, Fujisaki K, Masutani K, Kitazono T

    Renal failure   38 ( 3 )   390 - 6   2016( ISSN:0886-022X

  • Impact of the Triglycerides to High-Density Lipoprotein Cholesterol Ratio on the Incidence and Progression of CKD: A Longitudinal Study in a Large Japanese Population.

    Tsuruya K, Yoshida H, Nagata M, Kitazono T, Iseki K, Iseki C, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kimura K, Kondo M, Asahi K, Kurahashi I, Ohashi Y, Watanabe T

    American journal of kidney diseases : the official journal of the National Kidney Foundation   66 ( 6 )   972 - 83   2015.12( ISSN:0272-6386

  • Factors associated with serum soluble inhibitors of Wnt-β-catenin signaling (sclerostin and dickkopf-1) in patients undergoing peritoneal dialysis.

    Yamada S, Tsuruya K, Tokumoto M, Yoshida H, Ooboshi H, Kitazono T

    Nephrology (Carlton, Vic.)   20 ( 9 )   639 - 45   2015.09( ISSN:1320-5358

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  • Brain atrophy in peritoneal dialysis and CKD stages 3-5: a cross-sectional and longitudinal study.

    Tsuruya K, Yoshida H, Kuroki Y, Nagata M, Mizumasa T, Mitsuiki K, Yoshiura T, Hirakawa M, Kanai H, Hori K, Hirakata H, Kitazono T

    American journal of kidney diseases : the official journal of the National Kidney Foundation   65 ( 2 )   312 - 21   2015.02( ISSN:0272-6386

  • Fibroblast growth factor 23, but not parathyroid hormone, is associated with urinary phosphate regulation in patients on peritoneal dialysis.

    Yamada S, Tsuruya K, Tokumoto M, Yoshida H, Hasegawa S, Tanaka S, Eriguchi M, Nakano T, Masutani K, Ooboshi H, Kitazono T

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   19 ( 1 )   73 - 80   2015.02( ISSN:1744-9979

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  • Clinical Significance of Fronto-Temporal Gray Matter Atrophy in Executive Dysfunction in Patients with Chronic Kidney Disease: The VCOHP Study.

    Tsuruya K, Yoshida H, Haruyama N, Fujisaki K, Hirakata H, Kitazono T

    PloS one   10 ( 12 )   e0143706   2015

  • Dietary patterns and clinical outcomes in hemodialysis patients in Japan: a cohort study.

    Tsuruya K, Fukuma S, Wakita T, Ninomiya T, Nagata M, Yoshida H, Fujimi S, Kiyohara Y, Kitazono T, Uchida K, Shirota T, Akizawa T, Akiba T, Saito A, Fukuhara S

    PloS one   10 ( 1 )   e0116677   2015

  • Relationship between residual renal function and serum fibroblast growth factor 23 in patients on peritoneal dialysis.

    Yamada S, Tsuruya K, Taniguchi M, Yoshida H, Tokumoto M, Hasegawa S, Tanaka S, Eriguchi M, Nakano T, Kitazono T

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   18 ( 5 )   383 - 90   2014.10( ISSN:1744-9979

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  • Association of the triglycerides to high-density lipoprotein cholesterol ratio with the risk of chronic kidney disease: analysis in a large Japanese population.

    Tsuruya K, Yoshida H, Nagata M, Kitazono T, Hirakata H, Iseki K, Moriyama T, Yamagata K, Yoshida H, Fujimoto S, Asahi K, Kurahashi I, Ohashi Y, Watanabe T

    Atherosclerosis   233 ( 1 )   260 - 7   2014.03( ISSN:0021-9150

  • The clinical utility of serum tartrate-resistant acid phosphatase 5b in the assessment of bone resorption in patients on peritoneal dialysis.

    Yamada S, Tsuruya K, Yoshida H, Taniguchi M, Haruyama N, Tanaka S, Eriguchi M, Nakano T, Kitazono T

    Clinical endocrinology   78 ( 6 )   844 - 51   2013.06( ISSN:0300-0664

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  • Radial basis function-sparse partial least squares for application to brain imaging data.

    Yoshida H, Kawaguchi A, Tsuruya K

    Computational and mathematical methods in medicine   2013   591032   2013( ISSN:1748-670X

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  • Effectiveness of lanthanum carbonate treatment used in combination with other phosphate binders in peritoneal dialysis patients.

    Yamada S, Yoshida H, Taniguchi M, Tanaka S, Eriguchi M, Nakano T, Tsuruya K, Kitazono T

    Internal medicine (Tokyo, Japan)   51 ( 16 )   2097 - 104   2012( ISSN:0918-2918

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Outline of education staff

  • 統計解析のみならず,研究立案,指針や法令の理解,調整事務局業務,データマネジメント,品質管理なども含め,臨床研究にかかわるすべての職種の業務について理解し,臨床研究をマネジメントすることのできる人材が求められている.担当している臨床医科学(修士)/臨床研究管理学(博士)では,講義や演習を通して,臨床研究を実施,または支援することについて学び,発展させる方法を考える.

Charge of on-campus class subject

  • Clinical Research Management

    2024     Graduate school

  • Clinical Medicine

    2024     Graduate school

Academic Activities

  • 奈良県立医科大学 臨床研究審査会

    Role(s): Review, evaluation

    2023.06 - Now

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    Type:Scientific advice/Review 

  • 奈良県立医科大学 医の倫理委員会

    Role(s): Review, evaluation

    奈良県立医科大学 学長  2020.10 - Now

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    Type:Scientific advice/Review