Updated on 2026/02/20

写真a

 
IMOTO WAKI
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Lecturer
School of Medicine Department of Medical Science
Title
Lecturer
Affiliation
Institute of Medcine
Affiliation campus
Abeno Campus

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Lecturer  2024.04 - Now

  • School of Medicine 附属病院 感染症内科 

    2021.04 - 2024.03

  • School of Medicine 附属病院 呼吸器内科 

    2018.04 - 2021.03

  • School of Medicine Department of Medical Science 

    Lecturer  2024.04 - Now

Degree

  • 博士（医学） （ Osaka City University ）

Research Areas

  • Life Science / Infectious disease medicine  / Long COVID

  • Life Science / Bacteriology  / Stenotrophomonas maltophilia

  • Life Science / General internal medicine

  • Life Science / Respiratory medicine

  • Life Science / Infectious disease medicine

Research Interests

  • Stenotrophomonas maltophilia

  • Long COVID

  • DPC data

  • COVID-19後遺症

  • COVID-19の疫学

  • coronavirus disease 2019

  • Stenotrophomonas maltophilia

  • Long COVID

  • COVID-19

  • 免疫不全者の感染症

Research subject summary

  • 呼吸器感染症ワクチンに関する研究

  • COVID-19の合併症に関する疫学研究

  • Long COVID（COVID-19後遺症）に関する疫学研究

  • Stenotrophomonas maltophiliaの病原性および治療法の研究

Professional Memberships

  • 日本臨床微生物学会

    2025.09 - Now

  • 日本医真菌学会

    2025.03 - Now

  • 日本性感染症学会

    2022.10 - Now   Domestic

  • 日本性感染症学会

    2022.10 - Now

  • 日本エイズ学会

    2019.11 - Now   Domestic

  • 日本エイズ学会

    2019.11 - Now

  • 日本渡航医学会

    2019.06 - Now   Domestic

  • 日本渡航医学会

    2019.06 - Now

  • 緑膿菌・グラム陰性菌感染症研究会

    2018.07 - Now

  • 日本結核・非結核性抗酸菌症学会

    2015.09 - Now   Domestic

  • 日本結核・非結核性抗酸菌症学会

    2015.09 - Now

  • 日本感染症学会

    2015.08 - Now   Domestic

  • 日本感染症学会

    2015.08 - Now

  • 日本呼吸器学会

    2015.03 - Now   Domestic

  • 日本呼吸器学会

    2015.03 - Now

  • 日本化学療法学会

    2015.01 - Now   Domestic

  • 日本化学療法学会

    2015.01 - Now

  • 日本内科学会

    2014.06 - Now   Domestic

  • 日本内科学会

    2014.06 - Now

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Committee Memberships (off-campus)

  • 日本感染症学会   薬剤耐性(AMR)治療ガイダンス作成委員会  

    2024.08 - Now 

    　 More details

    薬剤耐性(AMR)治療ガイダンス作成委員

  • 日本臨床腫瘍学会   発熱性好中球減少症（FN）診療ガイドライン 作成ワーキンググループ  

    2021.12 - Now 

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    発熱性好中球減少症（FN）診療ガイドライン
    作成ワーキンググループ委員

Awards

  • 日本化学療法学会 学術奨励賞

    井本 和紀

    2025.05   日本化学療法学会  

  • 第98回日本感染症学会学術講演会・第72回日本化学療法学会総会 合同学会 若手優秀演題賞

    2024.06   日本感染症学会・日本化学療法学会  

  • Roche Infectious Disease Award 2023

    2023.12  

  • 第18回　日本化学療法学会西日本支部　支部長賞（臨床部門）

    井本　和紀

    2023.11   日本化学療法学会  

  • 第15回　日本化学療法学会西日本支部　支部奨励賞（基礎部門）

    井本　和紀

    2020.11   日本化学療法学会  

  • 第61回　日本感染症学会中日本地方会学術集会　学術奨励賞

    井本　和紀

    2018.11   日本感染症学会  

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Job Career (off-campus)

  • Osaka Metropolitan University

    2024.04 - Now

  • 大阪公立大学医学部附属病院   感染制御部

    2024.04 - Now

  • 大阪公立大学医学部附属病院   感染症内科

    2024.04 - Now

  • 医療法人錦秀会阪和第二泉北病院

    2023.04 - Now

  • 大阪公立大学医学部附属病院   感染症内科   病院講師

    2022.04 - 2024.03

  • Osaka Metropolitan University

    2022.04 - 2024.03

  • 大阪公立大学医学部附属病院   感染制御部   病院講師

    2022.04 - 2024.03

  • 市立岸和田市民病院   ICT/AST

    2021.04 - Now

  • 社会医療法人生長会ベルランド総合病院   ICT/AST

    2019.04 - Now

  • 社会医療法人生長会ベルランド総合病院   呼吸器内科   医員

    2015.04 - 2018.03

  • 社会医療法人生長会ベルランド総合病院   臨床研修室   臨床研修医

    2013.04 - 2015.03

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Papers

  • Efficacy of cefiderocol and levofloxacin against Stenotrophomonas maltophilia in a hemorrhagic pneumonia mouse model.

    Imoto W, Abe J, Sakurai N, Kawamoto K, Yamada K, Kaneko Y, Kakeya H

    Antimicrobial agents and chemotherapy   e0094425   2026.01（ ISSN:0066-4804 ）

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  • Evaluating the Impact of Linezolid Metabolites: PNU‐142300 and PNU‐142586 on the Development of Linezolid‐Induced Thrombocytopenia in Adult Patients Reviewed

    Norihiro Sakurai, Hiroshi Kawaguchi, Toya Matsui, Hironobu Nishiura, Kazuhiro Kobayashi, Waki Imoto, Wataru Shibata, Yasutaka Nakamura, Hiroshi Kakeya

    The Journal of Clinical Pharmacology   2025.11（ ISSN:0091-2700 ） （ eISSN:1552-4604 ）

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    Publishing type：Research paper (scientific journal)  

    Abstract

    Linezolid is a widely used antimicrobial agent in clinical practice; however, its usage is often limited by linezolid‐induced thrombocytopenia (LIT). While prior studies have assessed linezolid plasma concentrations, the clinical relevance of its metabolites, PNU‐142300 and PNU‐142586, remains unclear. This study aimed to investigate the association between these metabolite concentrations and LIT, and to identify predictive thresholds. This study retrospectively analyzed patients treated with linezolid at Osaka Metropolitan University Hospital between January 2017 and December 2024. Patient characteristics, trough concentrations (C <sub>trough</sub> ), AUC <sub>24</sub> , and pharmacokinetic parameters of linezolid and its metabolites were compared among patients with and without thrombocytopenia. Receiver operating characteristic (ROC) analysis identified thresholds for LIT prediction. Risk factors were assessed using multivariate logistic regression analysis. Forty‐eight patients were included, with thrombocytopenia developing in 26 patients (54.2%). C <sub>trough</sub> and AUC <sub>24</sub> of PNU‐142300 and PNU‐142586 were significantly higher in the thrombocytopenia group; meanwhile, linezolid C <sub>trough</sub> and AUC <sub>24</sub> did not differ significantly. ROC analysis identified C <sub>trough</sub> ≥1.43 µg/mL and AUC <sub>24</sub> ≥37.8 mg h/L for PNU‐142586 as predictive thresholds. Multivariate analysis revealed that linezolid therapy ≥14 days (OR = 9.53, P =  .044) and PNU‐142586 C <sub>trough</sub> ≥1.43 µg/mL (OR = 37.60, P =  .002) as independent risk factors. Elevated PNU‐142586 concentrations were associated with a higher cumulative incidence of LIT. Accumulation of linezolid metabolites, especially PNU‐142586, is closely associated with LIT. Monitoring of PNU‐142586 may improve the safety of linezolid therapy and support individualized dosing strategies.

    DOI： 10.1002/jcph.70124

    PubMed

  • Impact of coronavirus disease on the incidence rate of methicillin-resistant Staphylococcus aureus among hospitalized patients with lung cancer: a nationwide retrospective cohort study in Japan Reviewed

    Ihara Y., Kihara H., Imoto W., Okada N., Kakeya H., Kaneko Y.

    J Pharm Health Care Sci   11 ( 1 )   95   2025.10

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1186/s40780-025-00500-y.

  • Impact of the COVID-19 pandemic on infectious disease treatment and infection control in Japan: A retrospective multicenter study Reviewed

    Shigeki Kakuno, Waki Imoto, Koichi Yamada, Yasutaka Ihara, Kayoko Yamada, Makoto Tanaka, Gaku Kuwabara, Kana Sawa, Tsuneko Terachi, Tetsu Mizutani, Miyoshi Kitazato, Mayumi Yoshimura, Naoko Yoshii, Ayumi Shintani, Hiroshi Kakeya

    Heliyon   11 ( 12 )   e43490 - e43490   2025.07（ ISSN:2405-8440 ）

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    Authorship：Corresponding author   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.heliyon.2025.e43490

  • Development of an In Vitro Electrical Impedance Model to Assess Cytotoxicity and Antifungal Efficacy of Aspergillus fumigatus(タイトル和訳中)

    Kakuno Shigeki, Shibata Wataru, Kawamoto Kengo, Imoto Waki, Yamada Koichi, Niki Makoto, Kaneko Yukihiro, Umeyama Takashi, Miyazaki Yoshitsugu, Kakeya Hiroshi

    Medical Mycology Journal   66 ( 3 )   105 - 112   2025.07（ ISSN:2185-6486 ）

  • Prospective Analysis of Factors Influencing Inter-Individual Variation in Trough Plasma Voriconazole Concentrations in Older Patients—Impact of High <i>α</i>1-Acid Glycoprotein Levels

    Yasui Yukako, Yasui Hiroyuki, Yamamoto Yoshiki, Ishizaka Toshihiko, Hatanaka Kazuo, Imoto Waki, Shibata Wataru, Yamada Koichi, Kakeya Hiroshi

    Biological and Pharmaceutical Bulletin   48 ( 5 )   694 - 705   2025.05（ ISSN:09186158 ） （ eISSN:13475215 ）

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    <p>Voriconazole (VRCZ), an azole-based, deep-seated antifungal agent, is used as a 1st-line treatment for aspergillosis in Japan. VRCZ exhibits nonlinear pharmacokinetic (PK) behavior with relatively large inter-individual variability in plasma concentration. Additionally, genetic polymorphisms of CYP2C19 have been reported to influence the metabolic variability of VRCZ. The purpose of this study was to search for and identify clinically relevant potential factors influencing the PK and plasma concentration of VRCZ to better inform VRCZ dosing regimens. Thirty patients receiving VRCZ were enrolled. Total (C<sub>t</sub>) and unbound (C<sub>u</sub>) trough plasma concentrations of VRCZ were determined by the HPLC-UV method. Univariate and multivariate correlation analyses were used to evaluate the relationships between C<sub>t</sub> or C<sub>t</sub>/dose per body weight (C<sub>t</sub>/D) and individual demographic and laboratory characteristics. Since the increasing trend of C-reactive protein (CRP) inversely correlated with the classification of CYP2C19 gene polymorphisms, it was suggested that the inflammation counteracted the trend of C<sub>t</sub> according to CYP2C19 gene polymorphisms. Spearman’s rank-order correlation analysis showed significant correlations between C<sub>t</sub> and dose per body weight, CRP, and <i>α</i>1-acid glycoprotein (<i>α</i>1-AGP). Multivariate linear regression analysis showed that age, dose per body weight, CRP, and <i>α</i>1-AGP were significant explanatory factors for C<sub>t</sub>. In particular, elevated <i>α</i>1-AGP levels were found to have significant explanatory value for decreased C<sub>t</sub>. Although the present study has critical limitations, such as the patient sample was small in size and being limited to a single medical institution, this finding may explain some of the inter-individual variability in plasma VRCZ concentration.</p>

    DOI： 10.1248/bpb.b25-00057

    PubMed

    CiNii Research

  • Incidence and risk factors of COVID-19-associated pulmonary aspergillosis in severe cases: A single-center study from Japan Reviewed

    Kawamoto K., Imoto W., Kimura Y., Kakuno S., Shibata W., Myodo Y., Nishimura T., Ehara S., Fujii H., Mizobata Y., Shibata T., Kakeya H.

    J Infect Chemother   31 ( 4 )   102676   2025.03

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    Authorship：Corresponding author   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jiac.2025.102676.

  • 積極的な消化管内視鏡検査により診断が確定した膵周囲結核性リンパ節炎の1例

    木村 佳浩, 井本 和紀, 河本 健吾, 覺野 重毅, 柴多 渉, 掛屋 弘

    感染症学雑誌   99 ( 2 )   250 - 250   2025.03（ ISSN:0387-5911 ）

  • Assessment of incidence and risk factors of COVID-19-associated candidemia using diagnosis procedure combination data Reviewed

    Waki Imoto, Yasutaka Ihara, Tsubasa Bito, Ryota Kawai, Hiroki Namikawa, Wataru Shibata, Yukihiro Kaneko, Ayumi Shintani, Hiroshi Kakeya

    Journal of Infection and Chemotherapy   31 ( 5 )   102689 - 102689   2025.03（ ISSN:1341-321X ）

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.jiac.2025.102689

    PubMed

  • Development of an In Vitro Electrical Impedance Model to Assess Cytotoxicity and Antifungal Efficacy of Aspergillus fumigatus Reviewed

    Kakuno S., Shibata W., Kawamoto K., Imoto W., Yamada K., Niki M., Kaneko Y., Umeyama T., Miyazaki Y., Kakeya H.

    Med Mycol j   66 ( 3 )   105 - 112   2025.02

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.3314/mmj.25-00003.

  • Prospective Analysis of Factors Influencing Inter-Individual Variation in Trough Plasma Voriconazole Concentrations in Older Patients-Impact of High α1-Acid Glycoprotein Levels Reviewed

    Yasui Y., Yasui H., Yamamoto Y., Ishizaka T., Hatanaka K., Imoto W., Shibata W., Yamada K., Kakeya H.

    Biol Pharm Bull   48 ( 5 )   694 - 705   2025.01

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    Publishing type：Research paper (scientific journal)  

    DOI： 10.1248/bpb.b25-00057.

  • Incidence and risk factors for coronavirus disease 2019-associated pulmonary aspergillosis using administrative claims data. Reviewed

    Waki Imoto, Yasutaka Ihara, Takumi Imai, Ryota Kawai, Koichi Yamada, Yukihiro Kaneko, Ayumi Shintani, Hiroshi Kakeya

    Mycoses   67 ( 8 )   e13773   2024.08（ ISSN:09337407 ）

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    BACKGROUND: Coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) is one of the noticeable complications of COVID-19 and its incidence varies widely. In Japan, research on the incidence, risk factors and mortality associated with CAPA is limited. OBJECTIVES: This study aimed to explore the incidence and potential risk factors for CAPA in patients with severe or critical COVID-19 and evaluate the relationship between CAPA and mortality of patients with severe or critical COVID-19. METHODS: We investigated the incidence of CAPA in patients with severe and critical COVID-19 using administrative claims data from acute care hospitals in Japan. We employed multivariable regression models to explore potential risk factors for CAPA and their contribution to mortality in patients with severe and critical COVID-19. RESULTS: The incidence of CAPA was 0.4%-2.7% in 33,136 patients with severe to critical COVID-19. Age, male sex, chronic lung disease, steroids, immunosuppressants, intensive care unit admission, blood transfusion and dialysis were potential risk factors for CAPA in patients with severe to critical COVID-19. CAPA was an independent factor associated with mortality. CONCLUSIONS: CAPA is a serious complication in patients with severe and critical COVID-19 and may increase mortality.

    DOI： 10.1111/myc.13773

    PubMed

  • Incidence and potential risk factors of human cytomegalovirus infection in patients with severe and critical coronavirus disease 2019. Reviewed

    Waki Imoto, Takumi Imai, Ryota Kawai, Yasutaka Ihara, Yuta Nonomiya, Hiroki Namikawa, Koichi Yamada, Hisako Yoshida, Yukihiro Kaneko, Ayumi Shintani, Hiroshi Kakeya

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   31 ( 1 )   102452   2024.06（ ISSN:1341321X ）

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    BACKGROUND: Human cytomegalovirus (HCMV) infection occurs in immunosuppressed individuals and is known to increase mortality. Patients with coronavirus disease 2019 (COVID-19) are often treated with steroids, require intensive care unit (ICU) treatment, and may therefore be at risk for HCMV infection. However, which factors predispose severely ill patients with COVID-19 to HCMV infection and the prognostic value of such infections remain largely unexplored. This study aimed to examine the incidence and potential risk factors of HCMV infection in patients with severe or critical COVID-19 and evaluate the relationship between HCMV infection and mortality. METHODS AND FINDINGS: We used administrative claims data from advanced treatment hospitals in Japan to identify and analyze patients with severe or critical COVID-19. We explored potential risk factors for HCMV infection using multivariable regression models and its contribution to mortality in patients with COVID-19. Overall, 33,151 patients who progressed to severe or critical COVID-19 illness were identified. The incidence of HCMV infection was 0.3-1.7 % depending on the definition of HCMV infection. Steroids, immunosuppressants, ICU admission, and blood transfusion were strongly associated with HCMV infection. Furthermore, HCMV infection was associated with patient mortality independent of the observed risk factors for death. CONCLUSIONS: HCMV infection is a notable complication in patients with severe or critical COVID-19 who are admitted to the ICU or receive steroids, immunosuppressants, and blood transfusion and can significantly increase mortality risk.

    DOI： 10.1016/j.jiac.2024.06.015

    PubMed

  • Evaluation of predictors of third-generation cephalosporin non-susceptibility and factors affecting recurrence or death in bacteremia caused by Citrobacter freundii complex , Enterobacter cloacae complex, and Klebsiella aerogenes Reviewed

    Kazuhiro Kobayashi, Atsuko Hata, Waki Imoto, Shigeki Kakuno, Wataru Shibata, Koichi Yamada, Hiroshi Kawaguchi, Norihiro Sakurai, Toshikazu Ito, Kazuya Uenoyama, Tamotsu Takahashi, Satoru Ueda, Toshiro Katayama, Masahide Onoue, Hiroshi Kakeya

    J Chemother   36 ( 7 )   521 - 531   2024.05

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1080/1120009X.2024.2323326.

  • Evaluating the association of body mass index with COVID-19 severity and mortality using Japanese administrative claims data. Reviewed

    Waki Imoto, Yasutaka Ihara, Takumi Imai, Mitsuhiro Tamoto, Tatoi Ibuki, Koichi Yamada, Yukihiro Kaneko, Ayumi Shintani, Hiroshi Kakeya

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   30 ( 10 )   1054 - 1060   2024.04（ ISSN:1341321X ）

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    INTRODUCTION: Obesity is a risk factor for aggravation of and mortality from coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between COVID-19 and Body Mass Index (BMI) in the Japanese population. METHODS: We used administrative claims data from an advanced treatment hospital in Japan and extracted data from patients hospitalized for COVID-19. The exposure variable was BMI measured at the time of admission, and the study outcomes were progression to critical illness and death. Analyses were performed for each age group. RESULTS: Overall, 58,944 patients met the inclusion criteria. The risk of critical illness increased monotonically with higher BMI. In contrast, the relationship between BMI and mortality follows a J-shaped curve; being underweight and obese are risk factors for mortality. When stratified by age, similar trends were observed for both critical illness and mortality. CONCLUSION: A higher BMI is a risk factor for the progression of COVID-19 severity, whereas both lower and higher BMIs are risk factors for mortality in the Japanese population.

    DOI： 10.1016/j.jiac.2024.04.007

    PubMed

  • Evaluation of predictors of third-generation cephalosporin non-susceptibility and factors affecting recurrence or death in bacteremia caused by Citrobacter freundii complex, Enterobacter cloacae complex, and Klebsiella aerogenes. Reviewed

    Kazuhiro Kobayashi, Atsuko Hata, Waki Imoto, Shigeki Kakuno, Wataru Shibata, Koichi Yamada, Hiroshi Kawaguchi, Norihiro Sakurai, Toshikazu Ito, Kazuya Uenoyama, Tamotsu Takahashi, Satoru Ueda, Toshiro Katayama, Masahide Onoue, Hiroshi Kakeya

    Journal of chemotherapy (Florence, Italy)   36 ( 7 )   1 - 11   2024.03（ ISSN:1120009X ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    Factors involved in the susceptibility of third-generation cephalosporins (3GCs) to bacteremia caused by Citrobacter freundii complex, Enterobacter cloacae complex, and Klebsiella aerogenes were investigated based on a case-case-control design. Antimicrobial therapy administered 30 days prior to bacteremia and hospitalization within 90 days were common risk factors for the 3GC susceptible and 3GC non-susceptible groups, while hospitalization from an institution or another hospital was a specific risk factor for the 3GC non-susceptible group. We also attempted to examine the factors affecting the clinical outcome of bacteremia. Hospitalization more than 14 days before the onset of bacteremia was an independent factor indicating poor clinical outcome. In contrast, the implementation of source control was an independent predictor of successful treatment. Although a longer hospital stay before the onset of bacteremia was associated with worse clinical outcomes, implementation of source control may have contributed to improved treatment outcomes for bacteremia.

    DOI： 10.1080/1120009X.2024.2323326

    PubMed

  • Predictors of mortality from extended-spectrum beta-lactamase-producing Enterobacteriaceae bacteremia Reviewed

    Hiroki Namikawa, Waki Imoto, Koichi Yamada, Yoshihiro Tochino, Yukihiro Kaneko, Hiroshi Kakeya, Taichi Shuto

    Emerg Microbes Infect   12 ( 1 )   2217951   2023.12

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1080/22221751.2023.2217951.

  • Predictors for onset of extended-spectrum beta-lactamase-producing Escherichia coli-induced bacteraemia: a systematic review and meta-analysis Reviewed

    Namikawa H, Imoto W, Yamada K, Tochino Y, Kaneko Y, Kakeya H, Shuto T

    J Hosp Infect   142   88 - 95   2023.10

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.jhin.2023.09.017.

  • The Clinical Evaluation of Third-generation Cephalosporins As Definitive Therapy for Enterobacter spp. and Klebsiella aerogenes Bacteremia Reviewed

    Kazuhiro Kobayashi, Atsuko Hata, Waki Imoto, Shigeki Kakuno, Wataru Shibata, Koichi Yamada, Hiroshi Kawaguchi, Norihiro Sakurai, Kiyotaka Nakaie, Yukari Nakatsuka, Toshikazu Ito, Kazuya Uenoyama, Tamotsu Takahashi, Satoru Ueda, Toshiro Katayama, Masahide Onoue, Hiroshi Kakeya

    Intern Med   62 ( 13 )   1921 - 1929   2023.07

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    International / domestic magazine：International journal  

    DOI： 10.2169/internalmedicine.0612-22.

  • First report of Mycobacterium virginiense-induced synovitis and tenosynovitis of flexor digitorum superficialis and profundus muscles in Japan Reviewed OA

    Waki Imoto, Seishiro Matsumoto, Maya Suzuki, Nozomi Ban, Masayoshi Horikawa, Kei Mitani, Masashi Ogawa, Shigeki Kakuno, Wataru Shibata, Makoto Niki, Koichi Yamada, Mitsuhiro Okada, Hiroshi Kakeya

    J Infect Chemother   29 ( 4 )   410 - 413   2023.04

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2022.12.014.

    Repository URL： http://hdl.handle.net/10466/0002000428

  • Two cases of Clostridium ramosum bacteremia with intestinal perforation: The antimicrobial susceptibility of clinical strains Reviewed

    Kazushi Yamairi, Makoto Niki, Waki Imoto, Gaku Kuwabara, Wataru Shibata, Kazuhiro Oshima, Koichi Yamada, Yukihiro Kaneko, Hiroshi Kakeya

    Anaerobe   80   102695   2023.04

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.anaerobe.2023.102695.

  • Characterization of Aspergillus spp. isolated from patients with coronavirus disease 2019 Reviewed

    Masashi Ogawa, Makoto Niki, Waki Imoto, Akane Dobashi, Minami Imai, Naomi Takayama, Kei Mitani, Shigeki Kakuno, Wataru Shibata, Koichi Yamada, Hiroshi Kakeya

    J Infect Chemother   29 ( 6 )   580 - 585   2023.02

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2023.02.001.

  • Lomentospora prolificans-induced Invasive Fungal Sinusitis Reviewed

    Shigeki Kakuno, Waki Imoto, Yuichi Teranishi, Hiroshi Kakeya

    Intern Med   62 ( 18 )   2761 - 2762   2023.01

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.2169/internalmedicine.1074-22.

  • Muscle Biopsy-proven Drug-induced Microscopic Polyangiitis in a Patient with Tuberculosis Reviewed

    Gaku Kuwabara, Koichi Yamada, Kiyomi Tanaka, Satoshi Nozuchi, Waki Imoto, Wataru Shibata, Mitsunori Tohda, Shigenori Kyoh, Yoshiaki Itoh, Motomu Hashimoto, Hiroshi Kakeya

    Intern Med   62 ( 1 )   129 - 133   2023.01

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    International / domestic magazine：International journal  

    DOI： 10.2169/internalmedicine.9599-22.

  • A cross-sectional, multicenter survey of the prevalence and risk factors for Long COVID Reviewed OA

    Waki Imoto, Koichi Yamada, Ryota Kawai, Takumi Imai, Kengo Kawamoto, Masato Uji, Hidenori Kanda, Minoru Takada, Yoshiteru Ohno, Hiroshi Ohtani, Manami Kono, Atsuhito Hikiishi, Yosuke Eguchi, Hiroki Namikawa, Tomoya Kawaguchi, Hiroshi Kakeya

    Sci Rep   12 ( 1 )   22413   2022.12

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1038/s41598-022-25398-6.

    Repository URL： http://hdl.handle.net/10466/0002003058

  • Population pharmacokinetics of linezolid and its major metabolites PNU-142300 and PNU-142586 in adult patients Reviewed OA

    Norihiro Sakurai, Hiroshi Kawaguchi, Junko Abe, Gaku Kuwabara, Waki Imoto, Wataru Shibata, Koichi Yamada, Hiroyuki Yasui, Yasutaka Nakamur,a Hiroshi Kakeya

    Pharmacotherapy   42 ( 9 )   707 - 715   2022.09

    　More details

    International / domestic magazine：International journal  

    DOI： 10.1002/phar.2719.

    Repository URL： http://hdl.handle.net/10466/0002000424

  • Long COVID with intracranial microangiopathy Reviewed OA

    W Imoto, K Yamada, H Kakeya

    QJM   115 ( 8 )   539   2022.08

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    Authorship：Lead author   International / domestic magazine：International journal  

    DOI： 10.1093/qjmed/hcac139.

    Repository URL： http://hdl.handle.net/10466/0002003059

  • Impact of coronavirus disease 2019 on infectious disease treatment and infection control at a tertiary hospital in Japan Reviewed OA

    Waki Imoto, Koichi Yamada, Gaku Kuwabara, Wataru Shibata, Norihiro Sakurai, Yuka Nonose, Yasuyo Okada, Kiyotaka Nakaie, Akiko Fujita, Hiroshi Kakeya

    J Infect Chemother   28 ( 5 )   616 - 622   2022.05

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    Authorship：Lead author   International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2022.01.008.

    Repository URL： http://hdl.handle.net/10466/0002003060

  • Body Mass Index of Elderly Patients with Normal Renal Function as a Determining Factor for Initial Vancomycin Regimen Designing Reviewed

    Norihiro Sakurai, Hiroshi Kawaguchi, Gaku Kuwabara, Waki Imoto, Wataru Shibata, Koichi Yamada, Yasutaka Nakamura, Hiroshi Kakeya

    Chemotherapy   67 ( 3 )   193 - 200   2022

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1159/000522455.

  • Isoniazid-induced Immune Thrombocytopenia Reviewed

    Gaku Kuwabara, Kumiyo Tazoe, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Kazuhiro Oshima, Koichi Yamada, Yasuhiro Takagi, Satoshi Shiraishi, Masayuki Hino, Tomoya Kawaguchi, Hiroshi Kakeya

    Intern Med   60 ( 22 )   3639 - 3643   2021.11

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.2169/internalmedicine.6520-20.

  • Invasive pulmonary aspergillosis caused by Aspergillus terreus diagnosed using virtual bronchoscopic navigation and endobronchial ultrasonography with guide sheath and successfully treated with liposomal amphotericin B Reviewed

    Naoko Yoshii, Koichi Yamada, Makoto Niki, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Hiroki Namikawa, Kazuki Sakatoku, Kanako Sato, Toshiyuki Nakai, Kazuhiro Yamada, Tetsuya Watanabe, Kazuhisa Asai, Hiroshi Kakeya, Tomoya Kawaguchi

    Infection   49 ( 5 )   1049 - 1054   2021.10

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1007/s15010-020-01545-x.

  • Risk factor analysis for piperacillin-tazobactam-resistant Enterobacter spp. bacteremia at a tertiary hospital Reviewed

    Kazushi Yamairi, Koichi Yamada, Waki Imoto, Gaku Kuwabara, Wataru Shibata, Hiroki Namikawa, Kazuhiro Oshima, Kiyotaka Nakaie, Makoto Niki, Yukihiro Kaneko, Hiroshi Kakeya

    iagn Microbiol Infect Dis   100 ( 2 )   115342   2021.06

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.diagmicrobio.2021.115342.

  • Corynebacterium jeikeium-induced infective endocarditis and perivalvular abscess diagnosed by 16S ribosomal RNA sequence analysis: A case report Reviewed

    Waki Imoto, Yosuke Takahashi, Koichi Yamada, Kana Hojo, Takumi Kawase, Yoshito Sakon, Gaku Kuwabara, Kazushi Yamairi, Wataru Shibata, Kazuhiro Oshima, Masashi Ogawa, Makoto Niki, Kiyotaka Nakaie, Tetsuya Watanabe, Kazuhisa Asai, Yukihiro Kaneko, Tomoya Kawaguchi, Toshihiko Shibata, Hiroshi Kakeya

    J Infect Chemother   27 ( 6 )   906 - 910   2021.06

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2021.01.005.

  • COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report Reviewed

    Waki Imoto, Hoshi Himura, Kenji Matsuo, Sae Kawata, Ayako Kiritoshi, Ryo Deguchi, Masahiro Miyashita, Shinichiro Kaga, Tomohiro Noda, Katsumi Yamamoto, Koichi Yamada, Kenichiro Uchida, Tetsuro Nishimura, Hiromasa Yamamoto, Yasumitsu Mizobata, Hiroshi Kakeya

    J Infect Chemother   27 ( 6 )   911 - 914   2021.06

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    Authorship：Lead author   International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2021.02.026.

  • Incidental finding of neurosyphilis with intracranial hemorrhage and cerebral infarction: A case report Reviewed

    Waki Imoto, Hironori Arima, Koichi Yamada, Toshiyuki Kanzaki, Chihiro Nakagawa, Gaku Kuwabara, Kazushi Yamairi, Wataru Shibata, Kazuhiro Oshima, Tetsuya Watanabe, Kazuhisa Asai, Yukihiro Kaneko, Tomoya Kawaguchi, Takeo Goto, Hiroshi Kakeya

    J Infect Chemother   27 ( 3 )   521 - 525   2021.05

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2020.10.001.

  • In which cases of pneumonia should we consider treatments for Stenotrophomonas maltophilia? Reviewed OA

    W Imoto, K Yamada, G Kuwabara, K Yamairi, W Shibata, K Oshima, K Nakaie, T Watanabe, K Asai, Y Kaneko, T Kawaguchi, H Kakeya

    J Hosp Infect   111   169 - 175   2021.05

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.jhin.2021.01.011.

    Repository URL： http://hdl.handle.net/10466/0002003061

  • Three-year epidemiological analysis of Clostridioides difficile infection and the value of hospital-infection control measures in a tertiary-care teaching hospital in Japan using PCR-based open-reading frame typing Reviewed

    Kiyotaka Nakaie, Koichi Yamada, Gaku Kuwabara, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Kazuhiro Oshima, Makoto Niki, Norihiro Sakurai, Yuka Nonose, Yasuyo Okada, Akiko Fujita, Yukihiro Kaneko, Hiroshi Kakeya

    J Infect Chemother   27 ( 2 )   179 - 184   2021.02

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    International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2020.08.020.

  • Congenital bronchial atresia complicated by a lung abscess due to Aspergillus fumigatus: a case report Reviewed

    Gaku Kuwabara, Risa Sone, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Kazuhiro Oshima, Koichi Yamada, Kazuhiro Yamada, Tetsuya Watanabe, Kazuhisa Asai, Hiroaki Komatsu, Nobuhiro Izumi, Noritoshi Nishiyama, Tomoya Kawaguchi, Hiroshi Kakeya

    BMC Pulm Med   21 ( 1 )   2   2021.01

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1186/s12890-020-01367-5.

  • A mouse model of rapidly progressive fatal haemorrhagic pneumonia caused by Stenotrophomonas maltophilia Reviewed OA

    Waki Imoto, Yukihiro Kaneko, Koichi Yamada, Gaku Kuwabara, Kazushi Yamairi, Wataru Shibata, Kazuhiro Oshima, Makoto Niki, Kiyotaka Nakaie, Tetsuya Watanabe, Kazuhisa Asai, Tomoya Kawaguchi, Hiroshi Kakeya

    J Glob Antimicrob Resist   23   450 - 455   2020.12

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    Authorship：Lead author   Publishing type：Doctoral thesis   International / domestic magazine：International journal  

    DOI： 10.1016/j.jgar.2020.10.024.

    Repository URL： http://hdl.handle.net/10466/0002003159

  • Coronavirus disease with multiple infarctions Reviewed

    W Imoto, S Kaga, T Noda, K Oshima, Y Mizobata, H Kakeya

    QJM   113 ( 12 )   907 - 908   2020.12

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    Authorship：Lead author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1093/qjmed/hcaa240.

  • Blood culture reports by infectious disease physicians can improve prognosis of bacteremia, including weekend-onset cases Reviewed

    Koichi Yamada, Gaku Kuwabara, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Kazuhiro Oshima, Naoko Yoshii, Kiyotaka Nakaie, Makoto Niki, Yasuyo Okada, Akiko Fujita, Norihiro Sakurai, Yukihiro Kaneko, Hiroshi Kakeya

    Int J Infect Dis   100   174 - 179   2020.11

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    DOI： 10.1016/j.ijid.2020.08.013.

  • Clinical usefulness of very high serum soluble interleukin-2 receptor levels for the detection of tuberculous peritonitis in a patient with chronic myelogenous leukemia Reviewed

    Makoto Moriguchi, Hideo Koh, Tetsuya Hayashi, Hiroshi Okamura, Satoru Nanno, Yasuhiro Nakashima, Takahiko Nakane, Waki Imoto, Koichi Yamada, Hiroshi Kakeya, Masayuki Hino, Hirohisa Nakamae

    J Infect Chemother   26 ( 10 )   1054 - 1057   2020.10

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    International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2020.05.001.

  • The effect of intervention by an antimicrobial stewardship team on anaerobic bacteremia Reviewed

    Gaku Kuwabara, Satomi Yukawa, Koichi Yamada, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Naoko Yoshii, Tetsuya Watanabe, Kazuhisa Asai, Makoto Niki, Kiyotaka Nakaie, Yasuyo Okada, Akiko Fujita, Yukihiro Kaneko, Tomoya Kawaguchi, Hiroshi Kakeya

    Anaerobe   64   102214   2020.08

    　More details

    International / domestic magazine：International journal  

    DOI： 10.1016/j.anaerobe.2020.102214.

  • Disseminated Mycobacterium abscessus subsp. massiliense infection in a Good's syndrome patient negative for human immunodeficiency virus and anti-interferon-γ autoantibody: a case report Reviewed OA

    Waki Imoto, Koichi Yamada, Yuriko Hajika, Kousuke Okamoto, Yuka Myodo, Makoto Niki, Gaku Kuwabara, Kazushi Yamairi, Wataru Shibata, Naoko Yoshii, Kiyotaka Nakaie, Kazutaka Yoshizawa, Hiroki Namikawa, Tetsuya Watanabe, Kazuhisa Asai, Hiroshi Moro, Yukihiro Kaneko, Tomoya Kawaguchi, Yoshiaki Itoh, Hiroshi Kakeya

    BMC Infect Dis   20 ( 1 )   431   2020.06

    　More details

    Authorship：Lead author   International / domestic magazine：International journal  

    DOI： 10.1186/s12879-020-05136-x.

    Repository URL： http://hdl.handle.net/10466/0002003062

  • Clinical Characteristics of Rapidly Progressive Fatal Hemorrhagic Pneumonia Caused by Stenotrophomonas maltophilia Reviewed OA

    Waki Imoto, Koichi Yamada, Kazushi Yamairi, Wataru Shibata, Hiroki Namikawa, Satomi Yukawa, Naoko Yoshii, Kiyotaka Nakaie, Asao Hirose, Hideo Koh, Tetsuya Watanabe, Kazuhisa Asai, Hirohisa Nakamae, Yukihiro Kaneko, Tomoya Kawaguchi, Masayuki Hino, Hiroshi Kakeya

    Intern Med   59 ( 2 )   193 - 198   2020

    　More details

    Authorship：Lead author   International / domestic magazine：International journal  

    DOI： 10.2169/internalmedicine.3358-19.

    Repository URL： http://hdl.handle.net/10466/0002003063

  • The intervention by an antimicrobial stewardship team can improve clinical and microbiological outcomes of resistant gram-negative bacteria Reviewed

    Koichi Yamada, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Hiroki Namikawa, Naoko Yoshii, Hiroki Fujimoto, Kiyotaka Nakaie, Yasuyo Okada, Akiko Fujita, Hiroshi Kawaguchi, Yoshikatsu Shinoda, Yasutaka Nakamura, Yukihiro Kaneko, Hisako Yoshida, Hiroshi Kakeya

    J Infect Chemother   25 ( 12 )   1001 - 1006   2019.12

    　More details

    International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2019.05.026.

  • Clinical characteristics of bacteremia caused by hypermucoviscous Klebsiella pneumoniae at a tertiary hospital Reviewed

    Hiroki Namikawa, Koichi Yamada, Arata Sakiyama, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Naoko Yoshii, Makoto Niki, Kiyotaka Nakaie, Ken-Ichi Oinuma, Taishi Tsubouchi, Mamiko Niki, Yoshihiro Tochino, Yasuhiko Takemoto, Yukihiro Kaneko, Taichi Shuto, Hiroshi Kakeya

    Diagn Microbiol Infect Dis   95 ( 1 )   84 - 88   2019.09

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    International / domestic magazine：International journal  

    DOI： 10.1016/j.diagmicrobio.2019.04.008.

  • The effects of antifungal stewardship programs at a tertiary-care teaching hospital in Japan Reviewed

    Hiroshi Kawaguchi, Koichi Yamada, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Hiroki Namikawa, Naoka Yoshii, Kiyotaka Nakaie, Yasuyo Okada, Akiko Fujita, Yoshikatsu Shinoda, Yasutaka Nakamura, Yukihiro Kaneko, Katsuya Nagayama, Hiroshi Kakeya

    J Infect Chemother   25 ( 6 )   458 - 462   2019.06

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    International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2019.01.015.

  • Successful treatment of invasive pulmonary aspergillosis caused by Aspergillus felis, a cryptic species within the Aspergillus section Fumigati: A case report Reviewed

    Kazushi Yamairi, Kentaro Ido, Shigeki Nakamura, Makoto Niki, Waki Imoto 1, Wataru Shibata 1, Hiroki Namikawa 1, Hiroki Fujimoto 1, Koichi Yamada, Hirohisa Nakamae, Masayuki Hino, Yukihiro Kaneko, Yoshitsugu Miyazaki, Hiroshi Kakeya

    J Infect Chemother   25 ( 4 )   307 - 310   2019.04

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    International / domestic magazine：International journal  

    DOI： 10.1016/j.jiac.2018.10.016.

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Books and Other Publications

  • 発熱性好中球減少症（FN）診療ガイドライン　改訂第3版

    吉田稔、井本和紀ほか（CQ2　血液培養を行う場合, 異なる部位から2セット以上を採血することは推奨されるか？）

    南江堂  2024.02  （ ISBN:978-4-524-23376-2 ）

  • Respiratory Medicine

    （ Role： Joint author）

    2023.12  （ ISSN:1884-2887 ）

  • 呼吸器内科学レビュー2024-’25

    弦間昭彦、井本和紀、掛屋弘ほか（ Role： Joint author ,  Ⅰ章呼吸器感染症　10.医療・介護関連肺炎（NHCAP)）

    2023.11  （ ISBN:978-4-88378-476-9 ）

  • 糖尿病ケア+　2022年第19巻6号

    井本和紀、掛屋弘ほか（ Role： Joint author ,  疾患別！対応マニュアル：予防から対策まで　１肺炎・結核）

    メディカ出版  2022.11  （ ISSN:2436-6935 ）

Presentations

  • βラクタマーゼ産生菌感染症の 現状と治療面からの工夫 ペニシリナーゼ～カルバペネマーゼとどう闘うか Invited

    井本 和紀

    第95回日本感染症学会西日本地方会学術集会 第73回日本化学療法西日本支部総会 合同学会  2025.11 

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    Presentation type：Symposium, workshop panel (nominated)  

  • 重症COVID-19患者における帯状疱疹の発症率及び リスク因子・予後に関する検討～DPCデータを用いた研究～

    井本和紀, 金子幸弘, 掛屋弘

    第99回日本感染症学会総会・学術講演会 第73回日本化学療法学会総会 合同学会  2025.05 

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    Presentation type：Oral presentation (general)  

  • ブドウ糖非発酵菌

    金子 幸弘, 川村 英樹, 井本 和紀, 山田 康一

    日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集  2025.04  日本感染症学会・日本化学療法学会

  • 重症COVID-19患者における帯状疱疹の発症率及びリスク因子・予後に関する検討　DPCデータを用いた研究

    井本 和紀, 金子 幸弘, 掛屋 弘

    日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集  2025.04  日本感染症学会・日本化学療法学会

  • 重症COVID-19患者におけるカンジダ血症の発症割合及びリスク因子・予後に関する検討」 第11回日本医真菌学会関西支部「深在性真菌症研究会

    掛屋弘, 井本和紀, 金子幸弘

    第11回日本医真菌学会関西支部「深在性真菌症研究会」  2025.03 

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    Presentation type：Oral presentation (general)  

  • 血液疾患患者におけるポサコナゾールの血中濃度に影響する,遺伝子多型を含む因子解析

    安井 友佳子, 井本 和紀, 柴多 渉, 山田 康一, 掛屋 弘

    日本化学療法学会雑誌  2025.03  (公社)日本化学療法学会

  • 血液培養採取推進に向けた多職種による病棟ICTの取り組み評価

    岡田 恵代, 藤井 昭人, 藤田 明子, 仁木 誠, 河本 健吾, 覺野 重毅, 井本 和紀, 柴多 渉, 掛屋 弘

    感染症学雑誌  2025.03  (一社)日本感染症学会

  • VCMとTAZ/PIPC併用時の急性腎障害にVCMの血中濃度は関係するか

    松井 統哉, 川口 博資, 山下 佑麻, 出口 和貴, 櫻井 紀宏, 井本 和紀, 柴多 渉, 中村 安孝, 掛屋 弘

    日本化学療法学会雑誌  2025.03  (公社)日本化学療法学会

  • S. maltophilia菌血症に対してCefiderocolを投与した症例の検討の検討

    河本 健吾, 井本 和紀, 覺野 重毅, 柴多 渉, 西浦 広将, 掛屋 弘

    第59回緑膿菌・グラム陰性菌感染症研究会  2025.02 

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    Presentation type：Oral presentation (general)  

  • 当院でS.maltophilia菌血症に対してCefiderocolを投与した症例の検討

    河本 健吾, 井本 和紀, 木村 佳浩, 覺野 重毅, 柴多 渉, 西浦 広将, 掛屋 弘

    緑膿菌・グラム陰性菌感染症研究会プログラム・抄録集  2025.02  緑膿菌・グラム陰性菌感染症研究会

  • Body Mass IndexがCOVID-19患者の予後に与える影響～DPCデータを用いた研究～ Domestic conference

    井本 和紀, 山田 康一, 金子 幸弘, 掛屋 弘

    第94回日本感染症学会西日本地方会学術集会 第72回日本化学療法学会西日本支部総会  2024.11 

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    Presentation type：Oral presentation (invited, special)  

    Venue：兵庫県、神戸市  

  • Stenotrophomonas maltophilia出血性肺炎マウスモデルに 対するシデロフォアセファロスポリン系抗菌薬 セフィデロコルの有効性評価 Domestic conference

    井本 和紀, 河本 健吾, 山田 康一, 金子 幸弘, 掛屋 弘

    第94回日本感染症学会西日本地方会学術集会 第72回日本化学療法学会西日本支部総会  2024.11 

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    Presentation type：Oral presentation (general)  

    Venue：兵庫県、神戸市  

  • 症例報告の書き方 Invited Domestic conference

    井本和紀

    第94回日本感染症学会西日本地方会学術集会 第72回日本化学療法学会西日本支部総会  2024.11 

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    Presentation type：Symposium, workshop panel (nominated)  

  • 感染症入門講座「症例報告の書き方」 Invited

    井本 和紀

    第72回日本化学療法学会西日本支部総会  2024.11 

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    Presentation type：Symposium, workshop panel (nominated)  

  • COVID-19パンデミックが感染制御に与えた影響-多施設共同研究-

    覺野 重毅, 井本 和紀, 山田 康一, 寺地 つね子, 水谷 哲, 吉井 直子, 掛屋 弘

    第72回日本化学療法学会西日本支部総会  2024.11 

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    Presentation type：Oral presentation (general)  

  • 第18回日本化学療法学会 西日本支部長賞 受賞講演「Body Mass IndexがCOVID-19患者の予後に与える影響～DPCデータを用いた研究～」 Invited

    井本 和紀, 山田 康一, 金子 幸弘, 掛屋 弘

    第94回日本感染症学会西日本地方会学術集会 第72回日本化学療法学会西日本支部総会  2024.11 

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    Presentation type：Oral presentation (invited, special)  

  • 積極的な消化管内視鏡検査により診断が確定した膵周囲結核性リンパ節炎の一例

    木村 佳浩, 井本 和紀, 河本 健吾, 覺野 重毅, 柴多 渉, 掛屋 弘

    第94回日本感染症学会西日本地方会学術集会 第72回日本化学療法学会西日本支部総会  2024.11 

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    Presentation type：Oral presentation (general)  

  • Impact of coronavirus disease 2019 on infectious desease treatment and infection control: Multicenter study in Japan

    Hiroshi Kakeya, Shigeki Kakuno, Waki Imoto

    IDWeek2024  2024.10 

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    Presentation type：Poster presentation  

  • ポストコロナで求められる呼吸器感染症の病態理解と診断の重要性「 ブドウ糖非発酵菌の疫学・治療～Stenotrophomonas maltophiliaを中心に～」 Invited

    井本和紀

    第98回日本感染症学会学術講演会・第72回日本化学療法学会総会  2024.06 

  • 重症COVID-19患者におけるカンジダ感染症の発症率及びリスク因子・予後に関する検討〜DPCデータを用いた研究〜

    井本 和紀, 山田 康一, 金子 幸弘, 掛屋 弘

    第98回日本感染症学会学術講演会 第72回日本化学療法学会総会 合同学会  2024.06 

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    Presentation type：Oral presentation (general)  

  • 当院のAcinetobacter属菌による肺炎症例の検討

    河本 健吾, 井本 和紀, 覺野 重毅, 柴多 渉, 山田 康一, 明堂 由佳, 掛屋 弘

    第 98 回日本感染症学会学術講演会 第 72 回日本化学療法学会総会  2024.06 

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    Presentation type：Oral presentation (general)  

  • 電気抵抗値による細胞障害に焦点をあてたAspergillus fumigatusの新規評価法

    覺野 重毅, 河本 健吾, 井本 和紀, 柴多 渉, 山田 康一, 梅山 隆, 宮﨑 義継, 掛屋 弘

    第98回日本感染症学会学術講演会 第72回日本化学療法学会総会  2024.06 

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    Presentation type：Oral presentation (general)  

  • 電気抵抗値による細胞障害に焦点をあてたAspergillus fumigatusの新しい抗真菌薬活性の評価法

    覺野 重毅, 河本 健吾, 井本 和紀, 柴多 渉, 山田 康一, 梅山 隆, 宮崎 義継, 掛屋 弘

    日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集  2024.05  日本感染症学会・日本化学療法学会

  • 重症COVID-19患者におけるカンジダ感染症の発症率及びリスク因子・予後に関する検討　DPCデータを用いた研究

    井本 和紀, 山田 康一, 金子 幸弘, 掛屋 弘

    日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集  2024.05  日本感染症学会・日本化学療法学会

  • 新型コロナウイルスによる結核診療への時間的影響

    井本 和紀, 覺野 重毅, 柴多 渉, 山田 康一, 掛屋 弘

    結核  2024.05  (一社)日本結核・非結核性抗酸菌症学会

  • 当院におけるAcinetobacter属菌による肺炎症例の検討

    河本 健吾, 井本 和紀, 覺野 重毅, 柴多 渉, 山田 康一, 掛屋 弘, 明堂 由佳

    日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集  2024.05  日本感染症学会・日本化学療法学会

  • ポストコロナで求められる呼吸器感染症の病態理解と診断の重要性　ブドウ糖非発酵菌の疫学・治療　Stenotrophomonas maltophiliaを中心に

    井本 和紀

    日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集  2024.05  日本感染症学会・日本化学療法学会

  • ボリコナゾールの血中トラフ濃度の個体間変動に影響する諸因子の探索と評価

    安井 友佳子, 山本 圭城, 石坂 敏彦, 井本 和紀, 柴多 渉, 山田 康一, 掛屋 弘

    日本感染症学会総会・学術講演会・日本化学療法学会学術集会合同学会プログラム・抄録集  2024.05  日本感染症学会・日本化学療法学会

  • 蛍光イメージングと電気抵抗値を用いたAspergillus fumigatus　細胞間相互作用のリアルタイム評価

    覺野 重毅, 河本 健吾, 井本 和紀, 柴多 渉, 山田 康一, 梅山 隆, 宮崎 義継, 城戸 康年, 掛屋 弘

    感染症学雑誌  2024.03  (一社)日本感染症学会

  • Haemophilus influenzaeによる菌血症を呈した複雑性腎盂腎炎の1例

    木村 佳浩, 柴多 渉, 河本 健吾, 覺野 重毅, 井本 和紀, 山田 康一, 掛屋 弘

    感染症学雑誌  2024.03  (一社)日本感染症学会

  • COVID-19 Associated Pulmonary Aspergillosis(CAPA)の発症率およびリスク因子についての検討

    河本 健吾, 井本 和紀, 覺野 重毅, 柴多 渉, 山田 康一, 掛屋 弘

    感染症学雑誌  2024.03  (一社)日本感染症学会

  • Body Mass IndexがCOVID-19患者の予後に与える影響　DPCデータを用いた研究

    井本 和紀, 山田 康一, 金子 幸弘, 掛屋 弘

    日本化学療法学会雑誌  2024.03  (公社)日本化学療法学会

  • Actinotignum schaaliiによる椎間板炎と硬膜外膿瘍の1例

    道脇 唯人, 河本 健吾, 井本 和紀, 覺野 重毅, 柴多 渉, 仁木 誠, 山田 康一, 掛屋 弘

    感染症学雑誌  2024.03  (一社)日本感染症学会

  • Acinetobacter属菌による肺炎症例の検討

    河本 健吾, 井本 和紀, 覺野 重毅, 柴多 渉, 山田 康一, 明堂 由佳, 掛屋 弘

    日本呼吸器学会誌  2024.03  (一社)日本呼吸器学会

  • 当院におけるAcinetobacter属による肺炎症例の検討

    河本 健吾, 井本 和紀, 覺野 重毅, 柴多 渉, 山田 康一, 明堂 由佳, 掛屋 弘

    第58回緑膿菌感染症研究会  2024.01 

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    Presentation type：Oral presentation (general)  

  • Body Mass IndexがCOVID-19患者の予後に与える影響～DPCデータを用いた研究～ Domestic conference

    井本和紀, 山田康一, 金子幸弘, 掛屋　弘

    第71回日本化学療法学会西日本支部総会  2023.11 

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    Presentation type：Oral presentation (general)  

    Venue：富山県、富山市  

  • DPCデータを用いた重症COVID-19患者におけるサイトメガロウイルス感染症の発症率及びリスク因子の検討 Domestic conference

    井本和紀, 山田康一, 金子幸弘, 掛屋　弘

    第97回日本感染症学会総会・学術総会/第71回日本化学療法学会学術集会合同学会  2023.04 

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    Presentation type：Oral presentation (general)  

    Venue：神奈川県、横浜  

  • Hemorrhagic Pneumonia Caused by Stenotrophomonas maltophilia International conference

    Imoto W

    U.S.-Japan Cooperative Medical Sciences Program 2023 International Conference on Emerging Infectious Diseases in the Pacific Rim  2023.03 

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    Presentation type：Oral presentation (general)  

    Venue：Manila, Philippines  

  • Long COVIDの実態とリスク因子に関する多施設共同研究

    井本和紀、山田康一、掛屋 弘

    第92回日本感染症学会西日本地方会学術集会・第65回日本感染症学会中日本地方会学術集会・第70回日本化学療法学会西日本支部総会  2022.11 

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    Presentation type：Oral presentation (general)  

  • Host-Pathogen Interactionより考える新しい感染症治療戦略「Stenotrophomonas maltophiliaにおけるHost-pathogen interaction」 Invited Domestic conference

    井本和紀、掛屋 弘

    第92回日本感染症学会西日本地方会学術集会・第65回日本感染症学会中日本地方会学術集会・第70回日本化学療法学会西日本支部総会  2022.11 

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    Presentation type：Symposium, workshop panel (nominated)  

  • Good症候群患者に発症した播種性Mycobacterium abscessus subsp. massilienseの1例 Domestic conference

    井本和紀、桑原 学、柴多 渉、山田康一、金子幸弘、掛屋 弘

    第97回日本結核・非結核性抗酸菌症学会学術講演会  2022.07 

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    Presentation type：Oral presentation (general)  

    Venue：北海道、旭川市  

  • Good症候群患者に発症した播種性Mycobacterium abscessus subsp. massilienseの1例 Domestic conference

    井本和紀、桑原学、柴多渉、櫻井紀宏、山田康一、金子幸弘、掛屋弘

    第70回日本化学療法学会総会  2022.06 

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    Presentation type：Oral presentation (general)  

  • 大阪市立大学医学部附属病院におけるClostridium菌血症症例の検討 Domestic conference

    井本和紀、山田康一、掛屋　弘

    第51回日本嫌気性菌感染症学会総会・学術集会  2022.03 

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    Presentation type：Oral presentation (general)  

  • Stenotrophomonas maltophilia市中/院内/人工呼吸器関連肺炎のリスク因子の検討 Domestic conference

    井本和紀、桑原 学、柴多 渉、櫻井紀宏、山田康一、金子幸弘、掛屋 弘

    第69回日本化学療法学会西日本支部総会  2021.11 

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    Presentation type：Oral presentation (general)  

  • COVID-19が感染症診療・感染制御に与える影響 Domestic conference

    井本和紀、桑原 学、柴多 渉、櫻井紀宏、山田康一、掛屋 弘

    第69回日本化学療法学会西日本支部総会  2021.11 

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    Presentation type：Oral presentation (general)  

  • Stenotrophomonas maltophilia出血性肺炎マウスモデルの確立とキノロン系薬の有効性 Invited Domestic conference

    井本和紀、金子幸弘、桑原 学、柴多 渉、山田康一、掛屋 弘

    第69回日本化学療法学会西日本支部総会  2021.11 

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    Presentation type：Oral presentation (invited, special)  

  • 重症 COVID-19 患者に発症した CAPA（COVID-19 associated pulmonary aspergillosis）の1例 Domestic conference

    井本和紀、山田康一、桑原 学、山入和志、柴多　渉、大島一浩、掛屋　弘

    第69回日本化学療法学会総会  2021.05 

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    Presentation type：Poster presentation  

  • 脳出血発症契機に診断した神経梅毒の 1 例 Domestic conference

    井本和紀、山田康一、桑原 学、山入和志、柴多 渉、大島一浩、中家清隆、金子幸弘、掛屋 弘

    第95回日本感染症学会学術講演会  2021.05 

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    Presentation type：Poster presentation  

  • Stenotrophomonas maltophilia市中/院内/人工呼吸器関連肺炎のリスク因子の検討 Domestic conference

    井本和紀、山田康一、桑原　学、山入和志、柴多　渉、大島一浩、中家清隆、金子幸弘、掛屋　弘

    第55回緑膿菌感染症研究会  2021.02 

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    Presentation type：Oral presentation (general)  

  • Stenotrophomonas maltophilia出血性肺炎マウスモデルの確立とキノロン系薬の有効性 Domestic conference

    井本和紀、金子幸弘、山田康一、桑原　学、山入和志、柴多　渉、掛屋　弘

    第68回日本化学療法学会西日本支部総会  2020.11 

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    Presentation type：Oral presentation (general)  

    Venue：福岡県、福岡市  

  • 無菌検体におけるStenotrophomonas maltophiliaのキノロン感受性の検討 Domestic conference

    井本和紀、山田康一、桑原　学、山入和志、柴多　渉、吉井直子、中家清隆、金子幸弘、掛屋　弘

    第68回日本化学療法学会総会  2020.09 

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    Presentation type：Oral presentation (general)  

  • 病棟で施行した気管支鏡検査の感染症診断への有効性 Domestic conference

    井本和紀、山入和志、吉井直子、金田裕靖、浅井一久、川口智哉

    第43回日本呼吸器内視鏡学会学術集会  2020.06 

  • Stenotrophomonas maltophilia出血性肺炎マウスモデルの作成 Domestic conference

    井本和紀、山田康一、桑原　学、山入和志、柴多　渉、吉井直子、中家清隆、金子幸弘、掛屋　弘

    第54回緑膿菌感染症研究会  2020.02 

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    Presentation type：Oral presentation (general)  

  • 大阪市立大学医学部附属病院におけるStenotrophomonas maltophilia菌血症の後方視的検討～出血性肺炎との関連～ Domestic conference

    井本和紀、山田康一、山入和志、柴多　渉、並川浩己、吉井直子、中家清隆、金子幸弘、掛屋　弘

    第89日本感染症学会西日本地方会学術集会／第62回日本感染症学会中日本地方会学術集会／第67回日本化学療法学会西日本支部総会　合同学会  2019.11 

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    Presentation type：Oral presentation (invited, special)  

    Venue：静岡県  

  • 慢性骨髄性白血病の分子標的薬使用中に発症した結核性腹膜炎の１例 Domestic conference

    井本和紀、山入和志、柴多　渉、中家清隆、金子幸弘、掛屋　弘

    第94回日本結核病学会総会  2019.06 

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    Presentation type：Oral presentation (general)  

    Venue：大分県、大分市  

  • Stenotrophomonas maltophilia菌血症の症例対象研究～大阪市立大学医学部附属病院におけるブドウ糖非発酵菌菌血症での比較～ Domestic conference

    井本和紀、山田康一、山入和志、柴多　渉、並川浩己、吉井直子、中家清隆、金子幸弘、掛屋　弘

    第93回日本感染症学会総会・学術講演会  2019.04 

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    Presentation type：Oral presentation (general)  

  • Stenotrophomonas maltophilia菌血症の後ろ向き観察研究～大阪市立大学医学部附属病院におけるブドウ糖非発酵菌菌血症での比較～ Domestic conference

    井本和紀

    第53回緑膿菌感染症研究会  2019.03 

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    Presentation type：Oral presentation (general)  

    Venue：秋田県、秋田市  

  • 大阪市立大学附属病院におけるStenotrophomonas maltophilia菌血症の後方視的検討～出血性肺炎との関連～ Domestic conference

    井本和紀

    第53回緑膿菌感染症研究会  2019.03 

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    Presentation type：Oral presentation (general)  

  • Stenotrophomonas maltophilia菌血症の後方視的検討～出血性肺炎との関連～ Domestic conference

    井本和紀、山入和志、柴多 渉、並川浩己、吉井直子、中家清隆、山田康一、掛屋 弘

    第61回日本感染症学会中日本地方会学術集会／第66回日本化学療法学会西日本支部総会  2018.11 

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    Presentation type：Oral presentation (general)  

    Venue：鹿児島県  

  • COVID-19の流行に伴う喀痰からのStenotrophomonas maltophilia検出割合の変化についての検討

    河本 健吾, 井本 和紀, 木村 佳浩, 堀川 正悦, 柴多 渉, 明堂 由佳, 掛屋 弘

    第99回日本感染症学会総会・学術集会・第73回日本化学療法学会総会 

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    Presentation type：Oral presentation (general)  

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Grant-in-Aid for Scientific Research

  • 致死性マルトフィリア出血性肺炎の治療開発と病原因子の解明

    Grant-in-Aid for Scientific Research(C)  2028

  • 致死性マルトフィリア出血性肺炎の治療開発と病原因子の解明

    Grant-in-Aid for Scientific Research(C)  2027

  • 致死性マルトフィリア出血性肺炎の治療開発と病原因子の解明

    Grant-in-Aid for Scientific Research(C)  2026

  • 致死性マルトフィリア出血性肺炎の治療開発と病原因子の解明

    Grant-in-Aid for Scientific Research(C)  2025

  • 致死性マルトフィリア出血性肺炎の治療開発と病原因子の解明

    Grant-in-Aid for Scientific Research(C)  2024

Incentive donations / subsidies

  • Innovative Vaccine Accessibility System for Enhancing Respiratory Immunization in Older Adults and Development of a Health Information Infrastructure to Promote Behavioral Change

    Pfizer International LLC   2026.01

  • Host-pathogen interactionから迫る多剤薬剤耐性細菌の治療法開発

    公益財団法人　武田科学振興財団  2024年度医学系研究助成  2024.11

  • Host-pathogen Interactionを考慮したStenotrophomonas maltophilia感染症の治療法開発

    公益社団法人日本化学療法学会  創立70周年記念研究支援プログラム  2022

  • COVID-19回複者の後遺症に関する横断研究(アンケート送付による調査)―大阪市立大学による多施設共同研究―

    大阪難病研究財団  第27回大阪難病研究財団医学助成金  2021

  • Stenotrophomonas maltophilia出血性肺炎の病態・病原因子および治療法に関する研究

    杜の都医学振興財団  第1回研究費助成  2021

Other subsidies, etc.

  • COVID-19優秀賞

    ロシュ・ダイアグノスティックス株式会社  ロシュ感染症アワード2023  2023.12

Outline of education staff

  • 臨床医科学専攻・臨床感染制御学の大学院生指導

Charge of on-campus class subject

  • 感染症・化学療法７

    2025     Undergraduate

  • 感染制御セミナー

    2025   Intensive lecture   Graduate school

  • 臨床医科学演習（臨床感染制御学）

    2025   Intensive lecture   Graduate school

  • 特別研究

    2025   Intensive lecture   Graduate school

  • 臨床医科学（臨床感染制御学）

    2025   Intensive lecture   Graduate school

  • 研究指導

    2025   Intensive lecture   Graduate school

  • 発表表現演習

    2025   Intensive lecture   Graduate school

  • 感染制御セミナー（臨床感染制御学）

    2025   Intensive lecture   Graduate school

  • 感染症学実習（臨床感染制御学）

    2025   Intensive lecture   Graduate school

  • 感染症学研究演習（臨床感染制御学）

    2025   Intensive lecture   Graduate school

  • 臨床感染症基礎教育（臨床感染制御学）

    2025   Intensive lecture   Graduate school

  • 感染症セミナー（臨床感染制御学）

    2025   Intensive lecture   Graduate school

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Charge of off-campus class subject

  • M4ユニット型臨床臓器別講義 感染症・化学療法7 見逃せない感染症 part2 抗酸菌感染症

    2024.04
    -
    Now
    Institution：Osaka Metropolitan University

  • 細菌真菌感染症コース 統合型授業

    2024.02
    -
    Now
    Institution：Osaka Metropolitan University

  • 皮膚、骨、軟部組織感染症

    2021
    -
    Now

  • 手術部位感染症

    2021
    -
    Now

  • 微生物学

    2019.04
    -
    2020.03

Number of papers published by graduate students

  • 2025

    Number of graduate students presentations：2

  • 2024

    Number of graduate students presentations：1

  • 2023

    Number of graduate students presentations：2

  • 2022

    Number of graduate students presentations：4

Number of instructed thesis, researches

  • 2025

    Number of instructed the graduation thesis：1 

    [Number of instructed the Master's Program] (previous term)：3 

  • 2024

    Number of instructed the graduation thesis：1 

    [Number of instructed the Master's Program] (letter term)：2

  • 2023

    [Number of instructed the Master's Program] (letter term)：2

  • 2022

    [Number of instructed the Master's Program] (letter term)：1

Media Coverage

  • 新型コロナウイルス後遺症特集

    テレビ信州  2024.12

  • インフルエンザ報告件数急増に関して TV or radio program

    関西テレビ  旬感LIVEとれたてっ！  2023.10

  • 新型コロナウイルス後遺症特集

    日本テレビ  news every  2023.04

  • コロナ後遺症1年後も半数以上 Newspaper, magazine

    福島民友新聞  2023.01

  • 感染者の半数超1年後も後遺症 Newspaper, magazine

    北海道新聞  2023.01

  • 1年後も半数以上に後遺症　コロナ感染後、軽症でも Internet

    YAHOO!ニュース  2023.01

  • 「５類」へ引き下げ　コロナ後遺症の対策強化を Newspaper, magazine

    読売新聞東京本社調査研究本部  読売クオータリー  2023

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Original item・Special report (Social Activity)

  • 2024

    　 More details

    Original item：新型コロナウイルス後遺症に関する啓発活動

  • 2023

    　 More details

    Original item：新型コロナウイルス後遺症に関する啓発活動

  • 2022

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    Original item：新型コロナウイルス後遺症に関する啓発活動

  • 2021

    　 More details

    Original item：新型コロナウイルス後遺症に関する啓発活動

Foreigner acceptance

  • 2025

    foreigners accepted :1

International exchange activities

  • ASPIREプロジェクト

    Country name :Germany   2025.01 - Now

Job title

  • Job title within the department

    School of Medicine 附属病院 感染症内科 

    2024.04