2024/06/10 更新

写真a

ゴダイ カヨ
呉代 華容
GODAI KAYO
担当
大学院看護学研究科 看護学専攻 講師
看護学部 看護学科
職名
講師
所属
看護学研究院

担当・職階

  • 大学院看護学研究科 看護学専攻 

    講師  2024年04月 - 継続中

  • 看護学部 看護学科 

    講師  2024年04月 - 継続中

取得学位

  • 博士(看護学) ( 大阪大学 )

研究分野

  • ライフサイエンス / 臨床看護学

研究キーワード

  • 老年看護

  • 健康長寿

  • 循環器疾患リスク

  • 耐糖能異常

  • 脂質異常症

  • 高血圧

職務経歴(学外)

  • 大阪公立大学看護学部

    2024年04月 - 継続中

論文

  • Usefulness of the serum creatinine/cystatin C ratio as a blood biomarker for sarcopenia components among age groups in community-dwelling older people: The SONIC study.

    Wen Fang, Kayo Godai, Mai Kabayama, Yuya Akagi, Michiko Kido, Hiroshi Akasaka, Yoichi Takami, Kazunori Ikebe, Yasumichi Arai, Yukie Masui, Tatsuro Ishizaki, Saori Yasumoto, Yasuyuki Gondo, Koichi Yamamoto, Yasuharu Tabara, Kei Kamide

    Geriatrics & gerontology international   2024年04月

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    掲載種別:研究論文(学術雑誌)   国際・国内誌:国内誌  

    AIM: The serum creatinine/cystatin C ratio (CCR) or sarcopenia index is considered a useful marker of muscle mass. However, its usefulness in late-stage older adults remains unclear. We aimed to determine the usefulness of CCR as an indicator of sarcopenia in community-dwelling Japanese adults aged >75 years. METHODS: Our study recruited participants aged 70, 80, and 90 ± 1 years during the baseline years, and included a 3-year follow-up in the Septuagenarians, Octogenarians, Nonagenarians, Investigation with Centenarians study. From 2015 to 2018, 955 participants were eligible: 367 in their 70s, 304 in their 80s, and 284 in their 90s. The diagnostic components of sarcopenia, including "low muscle mass, plus low muscle strength, and/or low physical performance," were evaluated using the bioelectrical impedance analysis-measured skeletal muscle mass index (SMI), handgrip strength, and short physical performance battery (SPPB) score, respectively, in accordance with the Asia Working Group for Sarcopenia 2019 criteria. Separate analyses were performed between each component and CCR, adjusting for sex, body mass index, and other blood biomarkers in each group. RESULTS: The relationship between CCR and sarcopenia components was significant for handgrip strength (β = 0.21, 0.13, 0.19, and P < 0.0001, =0.0088, <0.0001, for the 70s, 80s, and 90s age groups, respectively); however, it was limited for SMI (β = 0.14; P = 0.0022, only for the 90s) and not significant for the SPPB score. CONCLUSION: CCR is a limited indicator of sarcopenia in late-stage older adults. Although its association with muscle strength was significant, its relationship with muscle mass and physical performance was less pronounced. Geriatr Gerontol Int 2024; ••: ••-••.

    DOI: 10.1111/ggi.14876

    PubMed

  • 乳がん検診受診経験のない女性従業員に対する情動的受診勧奨ツールの乳がん検診受診啓発効果: クラスターランダム化比較試験 査読

    滋賀医科大学雑誌   37 ( 1 )   20 - 27   2024年03月

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    担当区分:筆頭著者   掲載種別:研究論文(大学,研究機関等紀要)   共著区分:共著   国際・国内誌:国内誌  

    本研究では、クラスターランダム化比較研究により、乳がん検診を受けたことのない女性従業員への乳がん検診受診啓発における情動的受診勧奨ツールの効果について年代別に検討した。小売業企業の計120事業所を30事業所ずつ無作為に非介入群、情報提供群(乳がん検診に関する基本的情報と補助金申請書のチラシ配布)、情動的介入群(読み手の感情に訴えるマンガ冊子配布による受診勧奨)、チラシとマンガの両方を配布する重点介入群の4群に割り付け、それぞれの事業所に勤務する女性従業員に媒体を配布した。その後1年間における乳がん検診受診について、30~49歳の従業員では検診受診のオッズ比と95%信頼区間は、非介入群と比較して情報提供群で1.99 (0.54-7.28)、情動的介入群で2.50 (0.73-8.56)、重点介入群で3.41 (1.08-10.81)であった。50歳以上の従業員では有意な関連は見られなかった。従来型の情報提供による受診勧奨に情動的受診勧奨ツールを組み合わせることで、乳がん検診を受けたことのない30~40代の女性従業員の検診受診促進に効果がある可能性が示された。

    DOI: 10.14999/0002000119

  • Actual conditions for returning home after hospitalization among older patients receiving home medical care in Japan: OHCARE Study 査読 国際共著

    Naoko Murakami, Mai Kabayama, Tomoko Yano, Chika Nakamura, Yuka Fukata, Chihiro Morioka, Wen Fang, Yumiko Nako, Yuki Omichi, Eriko Koujiya, Kayo Godai, Michiko Kido, Winston Tseng, Taizo Wada, Toshinori Nakamura, Atsushi Hirotani, Toshio Fukuda, Michio Tamatani, Yoshinari Okuda, Masashi Ikushima, Yoshichika Baba, Masahiro Nagano, Yukio Nakamura, Hiromi Rakugi, Kei Kamide

    Geriatrics & Gerontology International   2024年01月( ISSN:1444-1586

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Aim

    To examine the actual conditions of older patients receiving home medical care after hospitalization over a period of 2 years in Japan.

    Methods

    The study population included 102 participants, aged ≥65 years, receiving home medical care, who consented to participate in the Osaka Home Care Registry (OHCARE) study in Japan over a period of 2 years. We investigated the actual conditions for returning home after hospitalization.

    Results

    The median age of the 102 participants was 84 years, and 61 (59.8%) were women. In the group that returned home, 42 (55.3%) of the respondents desired to recuperate in a familiar place, as in advanced care planning (ACP). During the 2‐year follow‐up period, the group that did not return home had significantly more deaths. A multivariate analysis showed the association in the presence of ACP (odds ratio: 4.72, 95% confidence interval: 1.60–13.86) and cardiac disease (odds ratio: 0.25, 95% confidence interval: 0.08–0.76). The lack of ACP in the medical records when the patient was admitted to the hospital may have prevented the return home.

    Conclusion

    In older patients who had difficulty returning home after hospitalization, the lack of ACP in home medical care may have been an influencing factor. ACP could help continue with home medical care. Geriatr Gerontol Int 2024; ••: ••–••.

    DOI: 10.1111/ggi.14802

  • Lifestyle factors associated with a rapid decline in the estimated glomerular filtration rate over two years in older adults with type 2 diabetes–Evidence from a large national database in Japan 査読

    Yaya Li, Makoto Fujii, Yuko Ohno, Asuka Ikeda, Kayo Godai, Yuko Nakamura, Yuya Akagi, Daisuke Yabe, Kazuyo Tsushita, Naoki Kashihara, Kei Kamide, Mai Kabayama

    PLOS ONE   18 ( 12 )   e0295235 - e0295235   2023年12月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Background

    The present study investigated lifestyle risk factors from metabolic syndrome-related lifestyles for a rapid decline in the estimated glomerular filtration rate (eGFR) among adults aged 40–74 years with treated and untreated type 2 diabetes.

    Methods and results

    This study analyzed data from the National Database of Health Insurance Claims and Specific Health Checkups of Japan, encompassing the period from fiscal year (FY) 2017 to FY2020. We established FY2018 as our baseline year. The subjects of this study were adults aged 40–74 in FY2018(baseline) who had type 2 diabetes and underwent specific health checkups in FY2020. We excluded adults with a medical record of kidney dialysis between FY2017 and FY2018, records of suspected type 1 diabetes between FY2017 and FY2020, or a baseline eGFR &gt;85 mL/min/1.73 m<sup>2</sup> or missing eGFR data as of FY2020. Eventually we analyzed 573,860 individuals. The outcome variable was a rapid decline in eGFR (≥30%) during the follow-up. Exposure lifestyle factors included skipping breakfast, late-night dinners, regular smoking, a high alcohol intake, non-refreshing sleep, and a lack of habitual exercise. Logistic regression models were stratified by age (40–59 and 60–74 years) and baseline eGFR levels (60–85, 30–59, and &lt;30 mL/min/1.73 m<sup>2</sup>). Covariates included sex, a history of heart disease, a history of stroke, a history of renal failure, anemia, low-density lipoprotein, systolic blood pressure, hemoglobin A1C, body mass index, antidiabetic medications, antihypertension drugs, lipid-lowering drugs, the oral adsorbent Kremezin, non-steroidal anti-inflammatory drugs, and drugs for the treatment of renal anemia. A rapid decline in eGFR was detected in approximately 1.3% of participants (7,683 cases). In the baseline eGFR &gt;30 subgroups (60–85 or 30–59 mL/min/1.73 m<sup>2</sup>), skipping breakfast and regular smoking were associated with a rapid decline in eGFR in both age groups, while a lack of habitual exercise and late-night dinners in the 60–74 age group and non-refreshing sleep in the 40–59 age group were identified as risk factors. Additionally, skipping breakfast was a risk factor for a rapid decline in eGFR in the 60–74 age group regardless of baseline eGFR levels. In the baseline eGFR &lt;30 mL/min/1.73 m<sup>2</sup> subgroup, skipping breakfast and non-refreshed sleep were risk factors for a rapid decline in eGFR.

    Conclusions

    We found specific lifestyle risk factors were associated with a rapid eGFR decline among people with type 2 diabetes from a nationwide database in Japan. The associations varied by baseline eGFR level, age, and sex. Lifestyle modifications may effectively prevent the aggravation of diabetic kidney disease.

    DOI: 10.1371/journal.pone.0295235

  • Factors influencing the continuation of home blood pressure measurement in community-dwelling older adults: the NOSE study. 査読

    Arisa Wada, Mai Kabayama, Kayo Godai, Michiko Kido, Yuka Ohata, Naoko Murakami, Yuko Nakamura, Hiroko Yoshida, Sumiyo Hashimoto, Makiko Higashi, Hiromi Hatanaka, Takeshi Kikuchi, Keiji Terauchi, Sho Nagayoshi, Fumie Matsuno, Noboru Shinomiya, Kei Asayama, Takayoshi Ohkubo, Hiromi Rakugi, Yasuharu Tabara, Kei Kamide

    Journal of hypertension   2023年12月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    OBJECTIVE: This study aimed to identify the factors influencing home blood pressure measurement (HBPM) continuation in community-dwelling older adults. METHODS: A longitudinal analysis used the NOSE study intervention group datasets. The participants were encouraged HBPM with self-monitoring devices provided to them twice in the morning and twice in the evening. Every 7-day interval from the HBPM start date was defined as 1 week, and the number of HBPMs per week was counted. The first week in which the number of HBPMs was zero was defined as the week in which HBPM was discontinued. Participants who did not experienced discontinuation until the end of the observation period were considered complete survivors in the survival time analysis. RESULTS: Data from 437 participants were included in the analysis. Of these, 120 (27.5%) discontinued HBPM. In univariate analysis, factors significantly associated with HBPM discontinuation included exercise habits [hazard ratio per one unit 0.47; 95% confidence interval (CI) 0.31-0.69], social participation (hazard ratio 0.65; 95% CI 0.42-0.99), MoCA-J score (hazard ratio 0.94; 95% CI 0.90-0.98), and frailty (hazard ratio 5.20; 95% CI 2.87-9.43). In multivariate analysis, factors significantly associated with HBPM discontinuation included sex (hazard ratio 0.55; 95% CI 0.32-0.95; ref. = female individuals), smoking history (hazard ratio 1.69; 95% CI 1.02-2.80), exercise habits (hazard ratio 0.51; 95% CI 0.30-0.85), MoCA-J score (hazard ratio 0.93; 95% CI 0.88-0.98), and frailty (hazard ratio 3.31; 95% CI 1.50-7.29). CONCLUSION: Among community-dwelling older adults, female sex, smoking history, lack of exercise, cognitive decline, and frailty were identified as factors influencing HBPM discontinuation.

    DOI: 10.1097/HJH.0000000000003628

    PubMed

  • Factors associated with weight loss by age among community-dwelling older people. 査読

    Tomoko Yano, Kayo Godai, Mai Kabayama, Hiroshi Akasaka, Yasushi Takeya, Koichi Yamamoto, Saori Yasumoto, Yukie Masui, Yasumichi Arai, Kazunori Ikebe, Tatsuro Ishizaki, Yasuyuki Gondo, Hiromi Rakugi, Kei Kamide

    BMC Geriatrics   23 ( 1 )   277   2023年05月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    BACKGROUND: Factors associated with weight loss in community-dwelling older people have been reported in several studies, but few studies have examined factors associated with weight loss by age groups. The purpose of this study was to clarify factors associated with weight loss by age in community-dwelling older people through a longitudinal study. METHODS: Participants in the SONIC study (Longitudinal Epidemiological Study of the Elderly) were community-dwelling people aged 70 or older. The participants were divided into two groups: 5% weight loss and maintenance groups, and compared. In addition, we examined factors affecting weight loss by age. The analysis method used was the χ2 test, and the t-test was used for comparison of the two groups. Factors associated with 5% weight loss at 3 years were examined using logistic regression analysis with sex, age, married couple, cognitive function, grip strength, and the serum albumin level as explanatory variables. RESULTS: Of the 1157 subjects, the proportions showing 5% weight loss after 3 years among all subjects, those aged 70 years, 80 years, and 90 years, were 20.5, 13.8, 26.8, and 30.5%, respectively. In logistic regression analysis, factors associated with 5% weight loss at 3 years by age were influenced by BMI of 25 or higher (OR = 1.90, 95%CI = 1.08-3.34, p = 0.026), a married couple (OR = 0.49, 95% = 0.28-0.86, p = 0.013), serum albumin level below 3.8 g/dL (OR = 10.75, 95% = 1.90-60.73, p = 0.007) at age 70, and the grip strength at age 90 (OR = 1.24, 95%CI = 1.02-1.51, p = 0.034), respectively. CONCLUSIONS: The results suggest that factors associated with weight loss by age in community-dwelling older people through a longitudinal study differ by age. In the future, this study will be useful to propose effective interventions to prevent factors associated with weight loss by age in community-dwelling older people.

    DOI: 10.1186/s12877-023-03993-0

    PubMed

  • Longitudinal association of hypertension and dyslipidemia with cognitive function in community-dwelling older adults: the SONIC study 査読 国際共著

    Yuko Nakamura, Mai Kabayama, Kayo Godai, Winston Tseng, Hiroshi Akasaka, Koichi Yamamoto, Yoichi Takami, Yasushi Takeya, Yasuyuki Gondo, Saori Yasumoto, Madoka Ogawa, Ayaka Kasuga, Yukie Masui, Kazunori Ikebe, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    Hypertension Research   2023年04月( ISSN:0916-9636

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Abstract

    The associations among cognitive function, hypertension, and dyslipidemia in older adults are controversial. Therefore, we investigated the associations among cognitive decline, hypertension, dyslipidemia, and their combination in community-dwelling older people in their 70s, 80s, and 90s in the long-term observational Septuagenarians, Octogenarians, Nonagenarians, Investigation with Centenarians (SONIC) study. We administered the Montreal Cognitive Assessment Japanese version (MoCA-J) by trained geriatricians and psychologists, and conducted blood testing and blood pressure (BP) measuring by medical staff involving 1186 participants. We performed multiple regression analysis to assess the relationships among hypertension, dyslipidemia, their combination, and lipid and BP levels with cognitive function at the 3-year follow-up after adjusting for covariate factors. At the baseline, the percentage of the combination of hypertension and dyslipidemia was 46.6% (n = 553), hypertension was 25.6% (n = 304), dyslipidemia was 15.0% (n = 178), and that without hypertension or dyslipidemia was 12.7% (n = 151). Conducting multiple regression analysis, no significant correlation was found between the combination of hypertension and dyslipidemia and MoCA-J score. In the group with the combination, high high-density lipoprotein cholesterol (HDL) levels resulted in higher MoCA-J scores at the follow-up (β = 0.06; P &lt; 0.05) and high diastolic BP (DBP) also resulted in higher MoCA-J scores (β = 0.08; P &lt; 0.05). The results suggest that high HDL and DBP levels of individuals with HT &amp; DL and high SBP levels of individuals with HT were associated with cognitive function in community-dwelling older adults.

    DOI: 10.1038/s41440-023-01271-5

    その他URL: https://www.nature.com/articles/s41440-023-01271-5

  • Effect of the Diabetic Nephropathy Aggravation Prevention Program on medical visit behavior in individuals under the municipal national health insurance. 査読

    Asuka Ikeda, Makoto Fujii, Yuko Ohno, Kayo Godai, Yaya Li, Yuko Nakamura, Daisuke Yabe, Kazuyo Tsushita, Naoki Kashihara, Kei Kamide, Mai Kabayama

    Journal of diabetes investigation   2023年03月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    AIMS/INTRODUCTION: We aimed to clarify the effectiveness of the Diabetic Nephropathy Aggravation Prevention Program in Japan by comparing the diabetes-related medical visit behavior of individuals under the municipal national health insurance according to insurers' effort levels. MATERIALS AND METHODS: We assessed changes in medical visit behavior according to insurers' effort levels, "Full Efforts," "Some Efforts" and "No Effort," using longitudinal data from the National Database of Health Insurance Claims and Specific Health Checkups before 2015 and after 2018 regarding the national health insurance programs in Japan. We analyzed the effect of the Diabetic Nephropathy Aggravation Prevention Program using a generalized linear mixed model for 208,388 participants with diabetes. RESULTS: The additive effect on medical visit behavior was significantly higher for insurers with "Full Efforts" than for those with "No Effort;" the coefficient (log odds ratio) was 0.159 (95% confidence interval 0.063-0.256). The additive effects on medical visit behavior sizes for the people with hemoglobin A1c ≥7.0%, positive urinary protein and systolic blood pressure ≥140 mmHg were 0.508, 0.402 and 0.232, respectively, which were larger than the overall effect size (0.159) for insurers with "Full Efforts." CONCLUSIONS: Our findings showed that insurer efforts had an additive effect on the increase in the number of medical visits, suggesting that this national program could reduce the number of end-stage renal failures or dialysis in Japan.

    DOI: 10.1111/jdi.14006

    PubMed

  • Lower cognitive function as a risk factor for anemia among older Japanese women from the longitudinal observation in the SONIC study 査読

    Tomoko Noma, Godai Kayo, Mai Kabayama, Yasuyuki Gondo, Saori Yasumoto, Yukie Masui, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    Geriatrics &amp; Gerontology International   2023年03月( ISSN:1444-1586

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    DOI: 10.1111/ggi.14571

    その他URL: https://onlinelibrary.wiley.com/doi/full-xml/10.1111/ggi.14571

  • Current status of the rapid decline in renal function due to diabetes mellitus and its associated factors: analysis using the National Database of Health Checkups in Japan. 査読

    Makoto Fujii, Yuko Ohno, Asuka Ikeda, Kayo Godai, Yaya Li, Yuko Nakamura, Daisuke Yabe, Kazuyo Tsushita, Naoki Kashihara, Kei Kamide, Mai Kabayama

    Hypertension research : official journal of the Japanese Society of Hypertension   2023年02月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    The increasing number of patients undergoing dialysis due to diabetes mellitus (DM) is causing serious economic problems, and its reduction is an urgent policy issue in developed countries, including Japan. We aimed to assess the association between the annual rapid decline in renal function and health checkup measures, including blood pressure, to identify health guidance targets for preventing diabetic nephropathy (DN) and diabetic kidney disease (DKD) among individuals in a medical checkup system ("Tokuteikenshin" program) in 2018. This longitudinal analysis included 3,673,829 individuals who participated in the "Tokuteikenshin" program in 2018, had hemoglobin A1c (HbA1c) levels ≥5.6%, were available for follow-up, and underwent estimated glomerular filtration rate (eGFR) evaluation. We estimated the incidence of the relative annual decrease in eGFR ≥10% per 1000 person-years and odds ratios to evaluate the rapid decline in renal function and determine health guidance goals and their role in preventing DN and DKD. Overall, 20.83% of patients with DM had a rapid decline in renal function within the observation period. A rapid decline in renal function was associated with high systolic blood pressure, poor or strict DM control, increased urinary protein excretion, and decreased blood hemoglobin levels. The incidence of rapid decline in renal function is higher in DM, and appropriate systolic blood pressure and glycemic control are important to prevent the progression to DN or DKD. Our findings will be useful for researchers, clinicians, and other public health care members in establishing effective health guidance and guidelines for CKD prevention.

    DOI: 10.1038/s41440-023-01185-2

    PubMed

  • Reply to comment on "Association between protein intake and changes in renal function among Japanese community-dwelling older people: The SONIC study". 査読

    Toshiaki Sekiguchi, Mai Kabayama, Kayo Godai, Hiroshi Akasaka, Kazunori Ikebe, Yukie Masui, Yasuyuki Gondo, Yasumichi Arai, Tatsuro Ishizaki, Kei Kamide

    Geriatrics & gerontology international   23 ( 2 )   156 - 157   2023年02月

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    掲載種別:研究論文(学術雑誌)   国際・国内誌:国際誌  

    DOI: 10.1111/ggi.14537

    PubMed

  • Offering on‐site mammography in workplaces improved screening rates: Cluster randomized controlled trial 査読

    Azusa Shima, Hideo Tanaka, Tomonori Okamura, Tomofumi Nishikawa, Ayumi Morino, Kayo Godai, Yukako Tatsumi, Mizuki Kawahara, Maiko Kiyohara, Yuichiro Kawatsu, Takashi Kimura, Naomi Miyamatsu

    Journal of Occupational Health   65 ( 1 )   2023年01月( ISSN:1341-9145

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    DOI: 10.1002/1348-9585.12389

    その他URL: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/1348-9585.12389

  • Age Group Differences in the Association Between Sleep Status and Frailty Among Community-Dwelling Older Adults: The SONIC Study. 査読

    Toshiki Mizuno, Kayo Godai, Mai Kabayama, Hiroshi Akasaka, Michiko Kido, Masaaki Isaka, Mio Kubo, Yasuyuki Gondo, Madoka Ogawa, Kazunori Ikebe, Yukie Masui, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    Gerontology & geriatric medicine   9   23337214231205432 - 23337214231205432   2023年

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Objective: We aimed to determine whether the association of sleep status with frailty differs between age groups of older adults. Method: This cross-sectional study was part of the observational Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians (SONIC) study. Subjects were community-dwelling older adults in their 70s and 80s. Frailty was evaluated using the Japanese version of the Cardiovascular Health Study criteria (J-CHS). Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep status. Poor sleep quality was defined as a PSQI global score ≥6. Sleep duration was categorized as short (<6 hr), normal (6-8), and long (>8). We performed multivariable logistic regression to investigate the association between sleep status and frailty separately for each age group adjusted for multiple covariates. Results: In those in their 70s, long sleep duration and sleep medication use were independently associated with frailty. In those in their 80s, poor sleep quality was independently associated with frailty. Conclusions: The association between sleep status and frailty was different between age groups. The findings underscore the importance of incorporating the evaluation of sleep quantity and non-pharmacological therapies in those in their 70s and the evaluation of sleep quality in those in their 80s to help prevent the onset of frailty.

    DOI: 10.1177/23337214231205432

    PubMed

  • [Relationship between glycemic control and mental health in community-dwelling older people with diabetes mellitus: The SONIC study]. 査読

    Yurie Maeyama, Mai Kabayama, Kayo Godai, Hiroshi Akasaka, Kouichi Yamamoto, Yasuyuki Gondo, Saori Yasumoto, Yukie Masui, Kazunori Ikebe, Yasumichi Arai, Tatsurou Ishizaki, Hiromi Rakugi, Kei Kamide

    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics   60 ( 2 )   141 - 152   2023年

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国内誌  

    AIM: The purpose of this study was to examine the relationship between glycemic control and mental health in community-dwelling older people with diabetes mellitus (DM) from insights that contribute to the management of diabetes in consideration of quality of life (QOL). METHODS: We used the data of the Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC) study, a prospective cohort study of community-dwelling older people. The present study included 2,051 older subjects of 70±1 years, 80±1 years and 90±1 years of age. We conducted medical interviews, blood sampling, and the subjects were asked to complete a questionnaire (WHO-5-J) at the venue. Three hundred sixty-eight people were diagnosed with DM. The subjects of this study were 192 people who were undergoing drug therapy for glycemic control. A multiple regression analysis was performed to clarify the relationship between glycemic control (divided as follows: HbA1c<7.0%, good control group; HbA1c≥7.0%, poor control group) and the WHO-5-J score, as the dependent variable, after adjusting for any confounding factors. RESULTS: In subjects of 70 years of age, a negative association was found between glycemic control and the WHO-5-J score, with the good control group showing a significantly lower score (β: -0.468, p<0.01) in comparison to the poor control group. In detail, we observed a significant difference in the sub-items of WHO-5-J, question item 3, "I have felt active and vigorous" at 70 years of age (good control group, 2.56±1.37; poor control group, 3.21±1.18; p=0.021) and question item 5, "My daily life has been filled with things that interest me" (good control group, 2.44±1.21; poor control group, 3.11±1.11; p=0.009). As for the two questions, the WHO-5-J scores were lower in the good control group. These associations showed no statistical significance at 80 years of age or 90 years of age. CONCLUSION: The results obtained in this study indicated that strict glycemic control management of diabetes mellitus may lead to a lower mental QOL in younger elderly individuals (70 years of age). Therefore, it is important to pay attention to the mental burdens of the management of glycemic control in older people with DM.

    DOI: 10.3143/geriatrics.60.141

    PubMed

  • Body mass, blood pressure, and cognitive functioning among octogenarians and centenarians 査読 国際共著

    Peter Martin, Rotem Arieli, Mai Kabayama, Kayo Godai, Yasuyuki Gondo, Mary Ann Johnson, Leonard W. Poon

    Exploration of Medicine   4 ( 5 )   625 - 636   2023年

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Aim: The purpose of this study was to examine the association among body mass, blood pressure (BP), and cognitive functioning for octogenarians and centenarians. Methods: A total of 300 participants (221 centenarians and 79 octogenarians) from the Georgia Centenarian Study were included in this study. Demographic variables included age, gender, and ethnicity. Body mass was measured with the body mass index (BMI), and systolic and diastolic BP, as well as mean arterial pressure (MAP) and the Mini-Mental Status Examination (MMSE) were assessed. Results: Results showed age differences indicating that centenarians had lower BMI and MMSE scores when compared to octogenarians. Women had lower cognitive functioning scores compared to men. Black Americans had higher BMI and BP as well as lower MMSE scores. Participants with low BMI values (< 18.5 kg/m2) and normal BP had a significantly lower MMSE score when compared to those with elevated BMI values (≥ 25 kg/m2 to < 30 kg/m2) and high BP. Multiple regression analyses determined that age, gender, ethnicity, and BMI were significantly associated with cognitive function in very late life. Conclusions: The results suggest that extreme values of body mass (low and high) in combination with normal BP (< 130 mmHg) are potential risk factors for compromised cognition.

    DOI: 10.37349/emed.2023.00165

  • Self-Monitoring Home Blood Pressure in Community-Dwelling Older People: Age Differences in White-Coat and Masked Phenomena and Related Factors—The SONIC Study 査読

    Jinmei Tuo, Kayo Godai, Mai Kabayama, Yuya Akagi, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Saori Yasumoto, Yukie Masui, Yasumichi Arai, Kazunori Ikebe, Yasuyuki Gondo, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    International Journal of Hypertension   2022   1 - 9   2022年04月( ISSN:2090-0384

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Some studies reported that home blood pressure (HBP) monitoring was conducted by community-dwelling older people themselves, but there have been few studies on HBP including very old populations aged over 90 years old. Thus, the aim of the present study was to clarify the current situation of white-coat and masked phenomena defined by on-site and home BP measurements in community-dwelling old and oldest-old populations. The study subjects were 380 participants from the SONIC study, a cohort study of a community-dwelling old population, who measured their HBP in a series of 3–5 days by themselves and brought their HBP records to the venue on the survey day. Study participants’ characteristics were as follows: female, 185 (48.7%); male, 195 (51.3%); 70s, 95 (25.0%); 80s, 245 (64.5%); and 90s, 40 (10.5%). A total of 344 (90.5%) participants had hypertension. A total of 291 (76.6%) hypertensive participants taking antihypertensive medication were analyzed in the present study. Regarding the types of hypertension defined by home and on-site BP, they showed white-coat phenomenon, 183 (48.2%); masked phenomenon, 115 (30.3%); sustained hypertension, 130 (34.2%); and normotension, 82 (21.6%). On comparison of age groups, there was a tendency for the white-coat phenomenon to be common in young-old people in their 70s and the masked phenomenon to be common in very old people in their 90s. Therefore, since the detection of white-coat and masked phenomena is closely associated with appropriate BP management, it is very important for community-dwelling older populations to self-monitor HBP.

    DOI: 10.1155/2022/5359428

    その他URL: http://downloads.hindawi.com/journals/ijhy/2022/5359428.xml

  • Cognitive decline and poor social relationship in older adults during COVID-19 pandemic: can information and communications technology (ICT) use helps? 査読

    Yaya Li, Kayo Godai, Michiko Kido, Susumu Komori, Ryoichi Shima, Kei Kamide, Mai Kabayama

    BMC geriatrics   22 ( 1 )   375 - 375   2022年04月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    BACKGROUND: To answer whether older adults' cognitive function benefits from ICT use, we (1) examined the relationship between ICT use and cognitive decline during the COVID-19 pandemic and (2) explored the potential role of ICT use in mitigating the relationship between loneliness, social isolation, and cognitive decline among community-dwelling older adults. METHODS: From February to March 2021, a mail survey was distributed to 1,400 older adults aged 70-89 years old. Responded participants were 1,003 (71.6% response rate). Subjective cognitive decline (SCD) was the independent variable. ICT use was assessed based on ICT use history and current ICT use activities. Loneliness was based on the Japanese version of the Three-Item Loneliness Scale. Social isolation was a total score of six items. Covariate-adjusted logistic regressions were performed and stratified by age groups (70-79 and ≥ 80 years). RESULTS: During the COVID-19 epidemic, the proportion of people aged ≥ 80 years who reported cognitive decline was twice that of 70s. Non-ICT use was independently associated with a higher risk of cognitive decline in participants aged ≥ 80 years. Furthermore, the significant associations between cognitive decline and interaction items (non-ICT use by loneliness or social isolation) were observed in the ≥ 80 age group. No association was found in the 70-79 age group. CONCLUSIONS: Non-ICT users with high loneliness or social isolation scores were more likely to experience cognitive decline for adults age ≥ 80 years. For older adults who were vulnerable to poor social relationships, ICT use is potentially an efficient intervention. Further longitudinal investigations are needed.

    DOI: 10.1186/s12877-022-03061-z

    PubMed

  • Association between protein intake and changes in renal function among Japanese community-dwelling older people: The SONIC study. 査読

    Toshiaki Sekiguchi, Mai Kabayama, Hirochika Ryuno, Kentaro Tanaka, Eri Kiyoshige, Yuya Akagi, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Saori Yasumoto, Yukie Masui, Kazunori Ikebe, Yasuyuki Gondo, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    Geriatrics & gerontology international   22 ( 4 )   286 - 291   2022年04月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    AIM: The aim of this study was to clarify the association between dietary protein intake and decline in the estimated glomerular filtration rate (eGFR) among Japanese older adults. METHODS: We used the data of the Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC) study, an ongoing narrow-age range cohort study: 69-71 years, 79-81 years and 89-91 years. The outcome variable, change in eGFR, was estimated from serum creatinine measured at the baseline and 3-year follow up, and the exposure variable, protein intake, was calculated using the brief-type self-administered diet history questionnaire at the baseline. Associations between eGFR change and protein intake were determined by multiple linear regression analysis. RESULTS: The mean eGFR change per year was -1.89 mL/min/1.73 m2 . The mean protein intake was 1.50 g/kg/day. The results of this study showed that there was no significant association between protein or animal protein intake and change in eGFR per year in the entire population of participants, including the very elderly, but there was a significant positive association in those whose renal function fell into chronic kidney disease stage G3 or G4. CONCLUSIONS: Protein intake among community-dwelling older adults was not associated with lower eGFR, and for older chronic kidney disease patients, protein and animal protein intakes were more beneficial in maintaining eGFR. The results provide evidence that protein intake should not be restricted for older patients with chronic kidney disease, including the very elderly. Geriatr Gerontol Int 2022; 22: 286-291.

    DOI: 10.1111/ggi.14355

    PubMed

  • Older Adults’ Resilience Against Impact of Lifestyle Changes During the COVID-19 Pandemic 査読

    Ayaka Kasuga, Saori Yasumoto, Takeshi Nakagawa, Yoshiko Ishioka, Akari Kikuchi, Hiroki Inagaki, Madoka Ogawa, Noriko Hori, Yukie Masui, Hwang Choe, Hiroyuki Muto, Mai Kabayama, Kayo Godai, Kazunori Ikebe, Kei Kamide, Tatsuro Ishizaki, Yasuyuki Gondo

    Gerontology and Geriatric Medicine   8   233372142211162 - 233372142211162   2022年04月( ISSN:2333-7214

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    掲載種別:研究論文(学術雑誌)  

    Background:

    Older adults were expected to experience a decline in physical activities and an increase in social isolation during the COVID-19 pandemic.

    Methods:

    We investigated the changes in living conditions of 508 older adults (79.70 years ± 0.88) before (from July to December 2019) and during (in August 2020) the pandemic. We compared the mean score for the same individual instrumental activities of daily living (IADL), frequency of going out, exercise, and social interaction at two-time points. We also examined the influence of living arrangement (living alone or not) on the frequency of exercise and social interaction.

    Results:

    The frequency of going out decreased during the pandemic (in 2020); however, there was no significant change in IADL. The frequency of exercise and social interaction increased irrespective of the living arrangement. The frequency of exercise increased more in those living alone.

    Conclusions:

    Although older adults refrained from going out, they compensated for the risks of inactivity in daily life by increasing or maintaining their frequency of exercise and social interactions. The view that “older adults have a poor ability to accommodate the lifestyle changes during the COVID-19 pandemic” may be a stereotypical assumption.

    DOI: 10.1177/23337214221116226

    その他URL: http://journals.sagepub.com/doi/full-xml/10.1177/23337214221116226

  • Alcohol drinking patterns have a positive association with cognitive function among older people: a cross-sectional study. 査読

    Yuya Akagi, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Saori Yasumoto, Nonglak Klinpudtan, Werayuth Srithumsuk, Kayo Godai, Kazunori Ikebe, Hiroshi Akasaka, Serina Yokoyama, Yoichi Nozato, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Ken Sugimoto, Yasumichi Arai, Hiroki Inagaki, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    BMC geriatrics   22 ( 1 )   158 - 158   2022年02月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    BACKGROUND: The relationship between moderate alcohol drinking or other alcohol drinking patterns such as frequency, beverage type, and situation of drinking and cognitive function is not sufficiently clear in older people. The purpose of this study was to investigate the association between alcohol drinking patterns and cognitive function in community-dwelling Japanese people aged 75 and over. METHODS: This study was a cross-sectional design based on a prospective cohort study called the SONIC study. Subjects were older people aged 75-77 or 85-87 who voluntarily participated in 2016-2017. Drinking information was collected for daily drinking frequency, daily drinking intake, beverage type, and non-daily drinking opportunity. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Other potential confounding factors evaluated were age, sex, medical factors, and psychosocial factors. An analysis of covariance was performed to evaluate the MoCA-J score relative to drinking frequency or alcohol intake. Multiple regression analysis was performed to investigate the association between beverage type or non-daily drinking opportunity and the MoCA-J score. RESULTS: The final number of participants analyzed was 1,226. The MoCA-J score for participants who reported drinking alcohol 1-6 days/week was significantly higher than that for those who reported drinking none or every day. No significant difference in the MoCA-J score was observed relative to daily alcohol intake. In terms of beverage type, wine was associated positively with the MoCA-J score. Non-daily drinking opportunity was also associated positively with the MoCA-J score. CONCLUSIONS: Moderate-frequency drinking, wine consumption, and non-daily drinking opportunities were associated with higher cognitive function in community-dwelling Japanese aged 75 and over. Further longitudinal studies are needed to clarify the causal relationships.

    DOI: 10.1186/s12877-022-02852-8

    PubMed

  • 地域在住後期高齢者における新型コロナウイルス感染症拡大に伴う活動量の変化とその関連因子についての検討 査読

    呉代 華容, 樺山 舞, 神出 計, 野上 素子, 春日 彩花, 安元 佐織, 増井 幸恵, 赤坂 憲, 池邉 一典, 石崎 達郎, 樂木 宏実, 権藤 恭之

    日本老年医学会雑誌   58 ( 4 )   591 - 601   2021年10月( ISSN:0300-9173

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国内誌  

    目的:新型コロナウイルス感染症の感染拡大を防ぐため,我が国では2020年4月から5月にかけ緊急事態宣言が発令され,外出自粛や人との接触を減らすことが奨励された.これにより,特に高齢者の心身機能への影響が懸念されたため,後期高齢者を対象に,活動量の主観的な変化について,年代,地域別に把握すること,またその関連因子を検討することを目的とした.方法:高齢者長期縦断疫学研究(SONIC研究)に参加している地域在住高齢者に郵送アンケート調査を実施し,自粛期間中(4,5月頃)の活動量,やる気の低下等について尋ねた.活動量減少についての集計を年齢コホート・地域別に行い,活動量減少に関連する要因についてロジスティック回帰分析を用いて検討した.結果:有効回答が得られた1,785名(回答率75.2%)のうち,分析対象者は70歳コホート753名,80歳コホート496名,90歳コホート293名の計1,542名であった.活動量が減少したと回答したのは70歳コホートで68.1%,80歳コホートで65.3%,90歳コホートで56.0%,地域別には都市部で69.4%,非都市部57.7%であった.活動量減少にはやる気が起きないことと新型コロナウイルスへの不安が強く関連したとともに,70歳・80歳コホートでは都市部で活動量減少が多かった.90歳コホートでは地域の影響は減弱し,経済状況にゆとりがないことと2年前の歩行速度1m/s以上であることが活動量減少に有意な関連を認めた.結論:活動自粛に伴う影響は年代,地域で異なっていた.コロナ禍での生活不活発による健康への悪影響を予防するためのアプローチは都市部においてより重要性が高いことが示唆された.また,90歳以上の超高齢群では元の身体状況や経済状況など70,80代とは異なる要因が活動量低下に関連することが明らかとなった.(著者抄録)

    その他URL: https://search-tp.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2021&ichushi_jid=J01214&link_issn=&doc_id=20211208220009&doc_link_id=10.3143%2Fgeriatrics.58.591&url=https%3A%2F%2Fdoi.org%2F10.3143%2Fgeriatrics.58.591&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  • The association between longevity associated FOXO3 allele and heart disease in Septuagenarians and Octogenarians: The SONIC study. 査読

    Nonglak Klinpudtan, Richard C Allsopp, Mai Kabayama, Kayo Godai, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Werayuth Srithumsuk, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Saori Yasumoto, Madoka Ogawa, Tatsuro Ishizaki, Yasumichi Arai, Hiromi Rakugi, Randi Chen, Bradley J Willcox, D Craig Willcox, Kei Kamide

    The journals of gerontology. Series A, Biological sciences and medical sciences   77 ( 8 )   1542 - 1548   2021年07月

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    掲載種別:研究論文(学術雑誌)   国際・国内誌:国際誌  

    The G allele of FOXO3 gene (Single nucleotide polymorphism - SNP; rs2802292) is strongly associated with human longevity. However, knowledge of the effect of FOXO3 in older populations, men or women, with heart disease is limited. This cross-sectional study in Japan included 1836 older adults in the 70 and 80-year-old groups. DNA samples isolated from buffy coat samples of peripheral blood were used to genotype FOXO3 (rs2802292). Self-reports were used to obtain heart disease data according to physician diagnosis. Multiple logistic regression was used to test the association by adjusting for the traditional risk factor of heart disease. The prevalence of heart disease in women FOXO3 G allele carriers was higher than non-carriers (16.7 vs. 11.6%, p=.022). The prevalence of coronary heart disease was lower for FOXO3 G carriers in the 70-year-old group for both sexes (men: 9.3 vs. 4.3%, p=.042, and women: 10 vs. 9%, p=.079, respectively). The G allele was negatively associated with heart disease after adjusting for diabetes, hypertension, dyslipidemia, and smoking in men (odds ratio (OR)= 0.70, 95%confidence intervals (CI), 0.49-0.99, p=.046), although the association was weaker after full adjustment. In contrast, women carriers of the FOXO3 G allele showed a positive association with heart disease after total adjustment (OR= 1.49, 95%CI, 1.00-2.21, p=.049). In conclusion, the longevity associated G allele of FOXO3 was observed to have contrasting associations with heart disease prevalence according to sex in older Japanese. To further confirm this association, a longitudinal study and a large sample size will be required.

    DOI: 10.1093/gerona/glab204

    PubMed

  • Association between physical function and onset of coronary heart disease in a cohort of community-dwelling older populations: The SONIC study. 査読

    Nonglak Klinpudtan, Mai Kabayama, Kayo Godai, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Werayuth Srithumsuk, Eri Kiyoshige, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Saori Yasumoto, Madoka Ogawa, Hiroki Inagaki, Tatsuro Ishizaki, Yasumichi Arai, Hiromi Rakugi, Kei Kamide

    Archives of gerontology and geriatrics   95   104386 - 104386   2021年03月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    BACKGROUND: Physical function is a strong predictor of the adverse outcomes of cardiovascular disease in older populations. However, studies of healthy older people on the prevention of coronary heart disease (CHD) are very limited. OBJECTIVES: We prospectively examined the association of walking speed and handgrip strength with CHD in the community-dwelling older populations. METHODS: The study cohort in Japan included 1272 older people free from heart disease at the baseline. Physical function was identified based on walking speed and handgrip strength assessment at the survey site. Any new case of CHD was identified based on a self-reported doctor's diagnosis. Cox-proportion hazard models were adjusted for covariate factors to examine the CHD risk. RESULTS: During the 7-year follow-up, 45 new cases of CHD (25 men and 20 women) were documented. Slow walking speed was strongly associated with CHD risk after adjusting for all confounding factors in the total participants and women (hazard ratio (HR)= 2.53, 95%confidence interval (CI), 1.20-5.33, p=0.015, and HR= 4.78, 95% CI,1.07-21.35, p=0.040, respectively), but not in men. Weak grip strength was associated with CHD after age-adjustment (HR= 2.45, 95%CI, 1.03-5.81, p=0.043) only in men. However, after additional multivariate adjustment, the associations were getting weaker.

    DOI: 10.1016/j.archger.2021.104386

    PubMed

  • Cluster-randomized controlled trial for the early promotion of clinic visits for untreated hypertension. 査読

    Azusa Shima, Hisatomi Arima, Katsuyuki Miura, Yukako Tatsumi, Takayoshi Ohkubo, Yuichiro Kawatsu, Ayumi Morino, Takashi Kimura, Kayo Godai, Saori Azuma, Naomi Miyamatsu

    Hypertension research : official journal of the Japanese Society of Hypertension   44 ( 3 )   355 - 362   2021年03月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Despite clear evidence of the benefits of lowering blood pressure among patients with hypertension, the treatment rate remains <40% worldwide. In the present trial, we aimed to investigate the effects of the early promotion of clinic visits among patients with untreated hypertension detected during annual health checkups. This was a worksite-based, parallel group, cluster-randomized trial with blinded outcome assessment. Employees of 152 Japanese supermarket stores found to have untreated hypertension (blood pressure levels ≥ 160/100 mmHg) during health checkups were assigned to an early promotion group (encouraged to visit a clinic in face-to-face interviews and provided with a referral letter to a physician as well as a leaflet) or a control group (received usual care), according to random assignment. The primary outcome was the completion of a clinic visit within 6 months. Odds ratios with 95% confidence intervals for the early promotion group versus the control group were estimated using multilevel logistic regression with random effects of clusters. A total of 273 participants (mean age 50.3 years, 55% women) from 107 stores were assigned to the early promotion group (138 from 55 stores) or control group (135 from 52 stores). During the 6-month follow-up, 47 (34.1%) participants in the early promotion group visited a clinic, as did 26 (19.3%) in the control group (odds ratio 2.33, 95% confidence interval 1.12-4.84, P = 0.024). Early promotion using a referral letter during health checkups significantly increased the number of clinic visits within 6 months completed by participants with untreated hypertension (UMIN000025411).

    DOI: 10.1038/s41440-020-00559-0

    PubMed

  • Effect of iki-iki hyakusai taiso on the prevention of progression of frailty in nose town, osaka prefecture 査読

    Jinmei Tuo, Mai Kabayama, Ya Huang, Yuya Akagi, Kayo Godai, Eri Kiyoshige, Hiromi Hatanaka, Sumiyo Hashimoto, Takeshi Kikuchi, Kei Kamide

    Japanese Journal of Geriatrics   58 ( 3 )   459 - 469   2021年( ISSN:0300-9173

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国内誌  

    Aim: We examined the effect of “IkiIki Hyakusai Taiso” as way to prevent the physical decline in community-dwelling elderly in Nose Town, Osaka Prefecture. Methods: Participants were community-dwelling elderly who participated in the Preventive Care program “IkiIki Hyakusai Taiso” from October 2015 to June 2019 in Nose Town, Osaka Prefecture, Japan. They performed exercises once a week. An as-sessment of the physical function, basic health checklist, and questionnaire about daily life were collected. Frailty was determined based on responses to the basic health checklist. Results: A total of 1,028 community-dwelling elderly people participated in this project. There were 766 (74.5%) women. The mean age of the participants was 72.6 ± 8.0 years old, and 506 participants (49.2%) were part of the young-old generation. The physical function measurement values, including the 5-meter walking speed, time up and go test (TUG), 5 times sit to stand, and grip strength all significantly improved. Ninety percent of the participants participated in this program every time it was held. Regarding the self-rated health questionnaire, the rate of “feeling good due to participating in the program” increased from 29.1% to 45.4% after participating in this program for 6 months. The prevalence of partial social activities was mostly an increasing trend among the participants of this program. Conclusion: Our findings showed that “IkiIki Hyakusai Taiso” improves and maintains the physical function and self-rated health among community-dwelling elderly individuals. Therefore, “IkiIki Hyakusai Taiso” seems to be a very useful preventive care program in the community.

    DOI: 10.3143/geriatrics.58.459

    PubMed

  • Association between uric acid and atherosclerosis in community‐dwelling older people: The SONIC study 査読

    Kentaro Tanaka, Mai Kabayama, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Toshiaki Sekiguchi, Eri Kiyoshige, Yuya Akagi, Kayo Godai, Saori Yasumoto, Yukie Masui, Yasuyuki Gondo, Kazunori Ikebe, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    Geriatrics & Gerontology International   2020年11月( ISSN:1444-1586

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    DOI: 10.1111/ggi.14081

    その他URL: https://onlinelibrary.wiley.com/doi/full-xml/10.1111/ggi.14081

  • Association between physical function and long-term care in community-dwelling older and oldest people: the SONIC study 査読

    Werayuth Srithumsuk, Mai Kabayama, Kayo Godai, Nonglak Klinpudtan, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Saori Yasumoto, Yasuyuki Gondo, Yasumichi Arai, Yukie Masui, Tatsuro Ishizaki, Hiroshi Shimokata, Hiromi Rakugi, Kei Kamide

    Environmental health and preventive medicine   25 ( 1 )   46   2020年09月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    BACKGROUND: Preventing the need for long-term care (LTC) by identifying physical function risk factors are important to decrease the LTC burden. The objective of this study was to investigate whether grip strength and/or walking speed, which are components of the frailty definition, are associated with LTC in community-dwelling older and oldest people. METHODS: The participants were 1098 community-dwelling older and oldest people who had not received LTC at the baseline. The endpoint was receiving LTC after the baseline survey. The independent variables were grip strength and walking speed, and participants were divided into two groups based on these variables. The confounding factors were age, sex, the Japanese version of the Montreal Cognitive Assessment (MoCA-J), hypertension, diabetes mellitus, stroke, joint diseases, living alone, body mass index, and serum albumin. We calculated the hazard ratio of receiving LTC using the Cox proportional hazard model. RESULTS: Among the 1098 participants, 107 (9.7%) newly received LTC during the follow-up. Regarding the physical function, only slow walking speed was significantly correlated with LTC after adjusting for all confounding factors except the MoCA-J score (HR = 1.74, 95% CI = 1.10-2.75, P = .018). However, slow walking speed was still a risk factor for LTC after adjusting for the MoCA-J score and other confounding factors (HR = 1.64, 95% CI = 1.03-2.60, P = .037). CONCLUSIONS: The findings from this study may contribute to a better understanding of slow walking speed as a factor related to LTC, which might be a criterion for disability prevention and could serve as an outcome measure for physical function in older people.

    DOI: 10.1186/s12199-020-00884-3

    PubMed

  • 特定保健指導積極的支援における中性脂肪該当者の特徴と中性脂肪に対する指導効果の検討 査読

    樋口 温子, 樺山 舞, 神出 計, 呉代 華容, 赤木 優也, 奥田 奈賀子, 中村 幸志, 渡邉 至, 栗林 徹, 板井 一好, 由田 克士, 三浦 克之, 岡山 明

    日本循環器病予防学会誌   55 ( 2 )   124 - 133   2020年09月( ISSN:1346-6267

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国内誌  

    【目的】特定健康診断を受検し、特定保健指導積極的支援に該当した者の中で、中性脂肪(TG)の基準に該当した対象者(TG≧150mg/dl)の特徴とTG値に対する特定保健指導の効果を検討することを目的とした。【方法】医療保険者155施設から収集したデータを用いた。2011年度に特定健診を受検して特定保健指導の積極的支援に割り付けられ、さらに翌年の特定健診を受診し、かつ服薬なしであった52,958名(男性82.8%)を解析の対象とした。TG基準該当者のうち、TG500mg/dl未満をTG高値者、500mg/dl以上をTG異常高値者とした。男女別に、TG基準非該当者と該当者、TG高値者と異常高値者の特性を比較した。また、それぞれの翌年のTG値を比較した。【結果】積極的支援該当者の中でTG基準該当者は男女ともに約半数を占めており、生活習慣としてはエネルギー過剰摂取につながるような、早食い、夕食後間食という食習慣がある男性が多く、運動習慣(男性のみ)・身体活動習慣がある者の割合が低いという特徴が明らかとなった。さらにTG異常高値者においては、高値者と比較して男性のみに高い喫煙率とハイリスク飲酒、就寝前夕食が関連していることが明らかとなった。保健指導のTGに対する効果は、減量達成した場合には特にTG減少量が大きくなることが認められた。またTG150ml/dl以上である場合は、BMI低下と独立したTG低下効果が認められ、さらに異常高値群では喫煙・飲酒の改善がTG減少量と関連を示した。【結論】保健指導積極的支援において、TG高値者およびTG異常高値者の特徴が明らかとなった。また特定保健指導にはTG低下効果があり、減量達成や喫煙・飲酒の改善が得られることによって、よりTG低下を促進する可能性が示唆された。今後は生活習慣の変化を踏まえた更なる検討が必要である。(著者抄録)

  • Recent status of self-measured home blood pressure in the Japanese general population: a modern database on self-measured home blood pressure (MDAS). 査読

    Kei Asayama, Yasuharu Tabara, Emi Oishi, Satoko Sakata, Takashi Hisamatsu, Kayo Godai, Mai Kabayama, Yukako Tatsumi, Jun Hata, Masahiro Kikuya, Kei Kamide, Katsuyuki Miura, Toshiharu Ninomiya, Takayoshi Ohkubo

    Hypertension research : official journal of the Japanese Society of Hypertension   43 ( 12 )   1403 - 1412   2020年08月

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    掲載種別:研究論文(学術雑誌)   国際・国内誌:国際誌  

    Despite the clinical usefulness of self-measured home blood pressure (BP), reports on the characteristics of home BP have not been sufficient and have varied due to the measurement conditions in each study. We constructed a database on self-measured home BP, which included five Japanese general populations as subdivided aggregate data that were clustered and meta-analyzed according to sex, age category, and antihypertensive drug treatment at baseline (treated and untreated). The self-measured home BPs were collected after a few minutes of rest in a sitting position: (1) the morning home BP was measured within 1 h of waking, after urination, before breakfast, and before taking antihypertensive medication (if any); and (2) the evening home BP was measured just before going to bed. The pulse rate was simultaneously measured. Eligible data from 2000 onward were obtained. The morning BP was significantly higher in treated participants than in untreated people of the same age category, and the BP difference was more marked in women. Among untreated residents, home systolic/diastolic BPs measured in the morning were higher than those measured in the evening; the differences were 5.7/5.0 mmHg in women (ranges across the cohorts, 5.3-6.8/4.7-5.4 mmHg) and 7.3/7.7 mmHg in men (ranges, 6.4-8.5/7.0-8.7 mmHg). In contrast, the home pulse rate in women and men was 2.4 (range, 1.5-3.7) and 5.6 (range, 4.6-6.6) beats per minute, respectively, higher in the evening than in the morning. We demonstrated the current status of home BP and home pulse rate in relation to sex, age, and antihypertensive treatment status in the Japanese general population. The approach by which fine-clustered aggregate statistics were collected and integrated could address practical issues raised in epidemiological research settings.

    DOI: 10.1038/s41440-020-0530-1

    PubMed

  • The association of blood pressure with physical frailty and cognitive function in community-dwelling septuagenarians, octogenarians, and nonagenarians: the SONIC study 査読

    Mai Kabayama, Kei Kamide, Yasuyuki Gondo, Yukie Masui, Takeshi Nakagawa, Madoka Ogawa, Saori Yasumoto, Hirochika Ryuno, Yuya Akagi, Eri Kiyoshige, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Hiroki Inagaki, Peter Martin, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi

    Hypertension Research   43 ( 12 )   1421 - 1429   2020年07月( ISSN:0916-9636

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    DOI: 10.1038/s41440-020-0499-9

    その他URL: http://www.nature.com/articles/s41440-020-0499-9

  • Association of anemia and SRH in older people: the SONIC study. 査読

    Tomoko Noma, Mai Kabayama, Yasuyuki Gondo, Saori Yasumoto, Yukie Masui, Ken Sugimoto, Hiroshi Akasaka, Kayo Godai, Atsuko Higuchi, Yuya Akagi, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Yasumichi Arai, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    Geriatrics & gerontology international   20 ( 7 )   720 - 726   2020年07月

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    AIM: The incidence of anemia increases with aging, and it is considered to affect mortality through complex pathophysiological outcomes. Although it has been suggested that self-rated health may also contribute to the prognosis of anemia in older people, the relationship between anemia and self-rated health is not well understood. This study thus examined the actual status of anemia in older community-dwelling Japanese people and clarified the relationship between anemia and self-rated health. METHODS: We conducted medical interviews, physical measurements and blood testing in 2083 people aged 69-91 years who participated in the long-term observational Septuagenarians, Octogenarians, Nonagenarians, Investigation with Centenarians (SONIC) study. Subjects were divided into two groups according to whether they had anemia. Logistic regression analyses were used to assess the relationship between anemia and self-rated health after adjusting for possible confounding factors. RESULTS: The prevalence of anemia was 22.3% in all participants, 7.2% in men and 11.6% in women aged 69-71 years, 27.4% in men and 26.3% in women aged 79-81 years, and 55.8% in men and 44.9% in women aged 89-91 years. Multivariate analysis revealed a correlation between the presence of anemia and poor self-rated health in all (odds ratio 0.67, 95% confidence interval 0.48-0.93) and aged 69-71 years (odds ratio 0.47, 95% confidence interval 0.25-0.86). CONCLUSIONS: Anemia was associated with self-rated health in older Japanese people, suggesting that careful management of anemia may contribute to health and longevity. Geriatr Gerontol Int 2020; ••: ••-••.

    DOI: 10.1111/ggi.13945

    PubMed

  • Work-related, personal, and diabetes-related factors relevant to dropout from outpatient diabetes treatment visits among Japanese male employees with diabetes 査読

    Nao Sonoda, Soichiro Watanabe, Yuko Ohno, Kayo Godai, Chieko Hatamochi, Yoshie Sugimoto, Satoko Okawa, Maiko Shikama, Akiko Morimoto

    DIABETOLOGY INTERNATIONAL   11 ( 3 )   261 - 268   2020年07月( ISSN:2190-1678

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    掲載種別:研究論文(学術雑誌)  

    AimIn recent years, support for coexisting diabetes treatment and work (Ryoritsu Shien) has become increasingly important for employees with diabetes. It is important to identify factors associated with dropout from outpatient visits for diabetes treatment among employees with diabetes to determine appropriate support to prevent dropout. Therefore, we explored work-related, personal, and diabetes-related factors relevant for dropout from outpatient diabetes treatment visits among Japanese employees with diabetes.MethodsThis cross-sectional study was conducted in 2018. Participants were 140 full-time employees with type 2 diabetes aged over 40 years. Participants were classified into two groups: a dropout group and a continuation group. Work-related, personal, and diabetes-related factors were evaluated using a self-administered questionnaire and specific health checkup data.ResultsOf the 140 employees with diabetes, 12 (8.6%) were classified in the dropout group. Multivariable logistic regression analysis revealed three factors associated with a lower risk for dropout from diabetes treatment outpatient visits. These were: high supervisor support, as measured by the Job Content Questionnaire (multivariable-adjusted odds ratio [OR] 0.71, 95% confidence interval [CI] 0.52-0.97, per 1 score); older age (multivariable-adjusted OR 0.79, 95% CI: 0.66-0.95, per 1 year); and presence of metabolic syndrome (multivariable-adjusted OR 0.04, 95% CI 0.01-0.28, presence vs. absence).ConclusionsOur findings suggest that supervisor support, age, and metabolic syndrome are important factors related to dropout from outpatient diabetes treatment visits among Japanese male employees with diabetes.

    DOI: 10.1007/s13340-019-00420-x

  • Day-to-day blood pressure variability is associated with lower cognitive performance among the Japanese community-dwelling oldest-old population: the SONIC study. 査読

    Kayo Godai, Mai Kabayama, Yasuyuki Gondo, Saori Yasumoto, Toshiaki Sekiguchi, Tomoko Noma, Kentaro Tanaka, Eri Kiyoshige, Yuya Akagi, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Yasumichi Arai, Yukie Masui, Tatsuro Ishizaki, Kazunori Ikebe, Michihiro Satoh, Kei Asayama, Takayoshi Ohkubo, Hiromi Rakugi, Kei Kamide

    Hypertension research : official journal of the Japanese Society of Hypertension   43 ( 5 )   404 - 411   2020年05月

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Although high blood pressure (BP) and BP variability have been reported to be associated with cognitive impairment, few studies have investigated the association between home BP (HBP) and cognitive function in the oldest-old. The aim of this study was to evaluate whether the value of and the day-to-day variability in HBP was associated with cognitive function in a Japanese community-dwelling oldest-old population. Among 111 participants aged 85-87 years, cognitive function was assessed using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). HBP was measured two times every morning for a median of 30 days. The value of and variability in HBP were calculated as the average and coefficient of variation (CV) of the measurements, respectively. The associations of HBP variability with MoCA-J were examined using multiple linear regression models. Of 111 participants, 47.7% were men, and 64.0% were taking medications for hypertension. The mean HBP was 141.9 ± 14.8/72.2 ± 8.4 mmHg, and the mean CV of HBP was 6.7 ± 1.9/6.8 ± 2.4. The mean total MoCA-J score was 22.9 ± 3.5. The MoCA-J score was significantly lower with increasing CVs of both systolic BP (b = -0.36, p = 0.034) and diastolic BP (b = -0.26, p = 0.046) after adjustment for possible confounding factors. The value of HBP was not associated with MoCA-J. In the community-dwelling oldest-old population, higher day-to-day HBP variability, but not the value of HBP, was associated with cognitive impairment. When measuring HBP, attention should be paid not only to the values but also to their variations.

    DOI: 10.1038/s41440-019-0377-5

    PubMed

  • The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study. 査読

    Werayuth Srithumsuk, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Nonglak Klinpudtan, Eri Kiyoshige, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Madoka Ogawa, Hiroki Inagaki, Tatsuro Ishizaki, Yasumichi Arai, Hiromi Rakugi, Kei Kamide

    BMC geriatrics   20 ( 1 )   24 - 24   2020年01月

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    掲載種別:研究論文(学術雑誌)   国際・国内誌:国際誌  

    BACKGROUND: Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this study was to investigate the importance of stroke as a risk factor of cognitive decline during 3 years in community dwelling older and oldest people. METHODS: This study was longitudinal study with a 3-year follow-up in Japan. The participants were 1333 community dwelling older and oldest people (70 years old = 675, 80 years old = 589, and 90 years old = 69). Data collected included basic data (age, sex, and history of stroke), vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and current smoking), and social factors (educational level, frequency of going outdoors, long-term care (LTC) service used, and residential area). The Japanese version of the Montreal Cognitive Assessment (MoCA-J) was decline of ≥2 points was defined as cognitive decline. Multiple logistic regression analysis was used to investigate the association between stroke and other risk factors with cognitive decline during a 3-year follow-up. RESULTS: The fit of the hypothesized model by multiple logistic regression showed that a history of stroke, advanced age, and greater MoCA-J score at the baseline were important risk factors, while the presence of dyslipidemia and a higher educational level were protective factors that were significantly correlated with cognitive decline during the 3-year follow-up. CONCLUSIONS: The cognitive decline after the 3-year follow-up was influenced by the history of stroke and advanced age, while greater MoCA-J score at the baseline was positively associated with subsequent 3 years cognitive decline. The protective factors were the presence of dyslipidemia and a higher educational level. Therefore, these factors are considered important and should be taken into consideration when searching for creative solutions to prevent cognitive decline after stroke in community dwelling older and oldest people.

    DOI: 10.1186/s12877-020-1423-5

    PubMed

  • Validation of an automated home blood pressure measurement device in oldest-old populations. 査読

    Kayo Godai, Mai Kabayama, Kanako Saito, Kei Asayama, Koichi Yamamoto, Ken Sugimoto, Takayoshi Ohkubo, Hiromi Rakugi, Kei Kamide

    Hypertension research : official journal of the Japanese Society of Hypertension   43 ( 1 )   30 - 35   2020年01月

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Despite the wide use of automated devices for the self-measurement of home blood pressure (BP), no evidence is available regarding the accuracy of such devices in oldest-old populations. The aim of this study was to validate the accuracy of the automated oscillometric upper arm-cuff BP-monitoring device according to an international protocol in oldest-old individuals. In 35 participants aged over 85 years old, BP was measured on the same arm sequentially using a mercury sphygmomanometer (by two observers) and an Omron HEM-7080IC. The difference between the test device and observer measurements and associated factors were evaluated according to the International Organization for Standardization (ISO) 81060-2:2013 protocol. A total of 105 pairs (three pairs per participant) of the test device and observer BP measurements were obtained. The mean (±standard deviation: SD) differences in systolic BP (SBP) and diastolic BP (DBP) between the methods were -0.7 ± 7.1 and -1.1 ± 4.5 mmHg, respectively, and those for each participant were -0.7 ± 5.8 mmHg for SBP and -1.1 ± 4.1 mmHg for DBP; the device therefore fulfilled the requirements of the ISO protocol. In the multivariate analysis with the linear mixed model, the difference was associated with the cuff size for SBP and pulse pressure for DBP. The Omron HEM-7080IC passed the ISO requirements for oldest-old individuals aged 85 years or older. This device can be recommended for clinical and self/home use in oldest-old populations.

    DOI: 10.1038/s41440-019-0330-7

    PubMed

  • Association between heart diseases, social factors and physical frailty in community-dwelling older populations: The septuagenarians, octogenarians, nonagenarians investigation with centenarians study 査読

    Nonglak Klinpudtan, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Werayuth Srithumsuk, Eri Kiyoshige, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Saori Yasumoto, Madoka Ogawa, Hiroki Inagaki, Tatsuro Ishizaki, Hiromi Rakugi, Kei Kamide

    Geriatrics and Gerontology International   20 ( 10 )   974 - 979   2020年( ISSN:1444-1586

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    © 2020 Japan Geriatrics Society Aim: Heart diseases and social factors are associated with physical frailty, but there are few studies of older people living in the community. Consequently, the aim of this study was to examine the association between heart diseases, social factors and physical frailty in community-dwelling older populations including the oldest-old people. Methods: The cross-sectional study included 1882 participants of community-dwelling older and oldest-old people. The survey site assessed questionnaires on medical history, social factors, blood samples and physical examination. Physical frailty was based on slow gait speed or weak grip strength. Associations were analyzed using multiple logistic regression with adjustments for covariate factors. Results: Subjects with heart disease had a higher prevalence of physical frailty than those without heart disease. After adjusting the covariate factors, heart diseases were associated with a slow gait speed (odds ratio [OR] = 1.62; 95% confidence interval [CI]: 1.13–2.32, P = 0.009). Frequency of going outdoors and direct interaction with relatives or friends were associated with a slow gait speed (OR = 0.83, 95% CI 0.75–0.91, P ≤ 0.001 and OR = 0.87, 95% CI 0.81–0.94, P < 0.001), and associated with physical frailty (OR = 0.80, 95% CI 0.72–0.89, P ≤ 0.001 and OR = 0.88, 95% CI 0.82–0.95, P = 0.002). Living alone and frequency of direct interaction with relatives or friends were associated with physical frailty in subjects with heart disease. Conclusions: Our findings indicate that in community-dwelling older people, heart diseases and social factors were associated with physical frailty. Older people with heart disease, those living alone and the frequency of direct interaction with relatives or friends were associated with physical frailty. Geriatr Gerontol Int ••; ••: ••–•• Geriatr Gerontol Int 2020; ••: ••–••.

    DOI: 10.1111/ggi.14002

    PubMed

  • Associations among work-related stress and mental fatigue, and regular exercise in Japanese employees with or without diabetes 査読

    Akiko Morimoto, Soichiro Watanabe, Yuko Ohno, Kayo Godai, Chieko Hatamochi, Yoshie Sugimoto, Satoko Okawa, Maiko Shikama, Nao Sonoda

    DIABETOLOGY INTERNATIONAL   11 ( 2 )   105 - 113   2019年10月( ISSN:2190-1678

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    掲載種別:研究論文(学術雑誌)   共著区分:共著   国際・国内誌:国際誌  

    Aim Understanding work-related factors associated with regular exercise in employees could be useful for determining appropriate interventions to prevent the onset and aggravation of diabetes. This study aimed to assess the associations among work-related stress and mental fatigue, and regular exercise in Japanese employees with or without diabetes. Methods This cross-sectional study was conducted in 2018, and included 2916 full-time employees aged older than 40 years without cardiovascular disease, cancer, respiratory disease, kidney disease, disc herniation, and depression. Work-related stress was measured by the Job Content Questionnaire and work-related mental fatigue was measured using the Numerical Rating Scale (NRS). Results Regular exercise was present in 23.9% of 117 employees with diabetes and in 21.3% of 2799 employees without diabetes. In employees with diabetes, the multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for regular exercise were 0.26 (0.07-0.96) in those with an NRS score of 4-6 (moderate) and 0.22 (0.06-0.85) in those with an NRS score of 7-10 (severe) compared with those with an NRS score of 0-3 (none or mild), after adjusting for confounding factors. Similarly, in employees without diabetes, the multivariable-adjusted ORs (95% CIs) for regular exercise were 0.77 (0.62-0.97) in those with an NRS score of 4-6 and 0.75 (0.59-0.94) in those with an NRS score of 7-10 compared with those with an NRS score of 0-3. Conclusions Work-related mental fatigue was negatively associated with regular exercise in employees with and without diabetes.

    DOI: 10.1007/s13340-019-00410-z

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MISC(その他記事)

  • 高齢者における血圧管理を考える

    神出 計, 糀屋 絵理子, 呉代 華容, 樺山 舞

    日本循環器病予防学会誌   57 ( 3 )   173 - 182   2022年11月( ISSN:1346-6267

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    高齢者における循環器疾患予防の観点から、非常に頻度が高い高血圧の管理をいかに適切に行うかが重要な鍵となる。しかしながら高齢者高血圧患者の血圧管理基準については様々な点において未だに議論が絶えない。高齢者は65歳から100歳以上と非常に幅が広く、個人の身体機能や認知機能にばらつきが大きいこと、降圧目標値が決めにくい、高血圧や降圧の影響が脳心血管病発症のみならず認知症などの老年症候群にも深く関わること、特に減塩などの生活習慣修正が低栄養などとも関連しやすいことなど、考慮すべき点が非常に多いことなどが背景にある。これらを考慮すると、現在の高血圧治療ガイドライン2019で示されているように、日常生活機能が保たれた高齢者では、脳心血管病の発症を抑制するため厳格な降圧を行うが、虚弱高齢者においては、自覚症状や老年症候群などの進行を評価しながら、降圧開始基準や降圧目標を個別に設定する必要がある。家庭血圧測定を行いながらの細やかな血圧管理が重要と考えられる。(著者抄録)

  • 高血圧治療ガイドラインに準拠した高血圧治療

    呉代 華容, 神出 計

    人間ドック   37 ( 1 )   7 - 14   2022年06月( ISSN:1880-1021 ( eISSN:2186-5027

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    高血圧は最も罹患者数の多い生活習慣病であり、脳血管疾患や虚血性心疾患、慢性心不全などの重大なリスク因子である。また、高齢者では老年症候群の発症・進展にも影響することが明らかにされている。高血圧治療の目的は、脳心血管病の発症・進展・再発の抑制とともに、それらによる死亡を減少させること、また、高血圧者がより健康で高いQOLを保った日常生活ができるように支援することであり、健康日本21(第二次)で掲げられている健康寿命の延伸の達成には、血圧を良好にコントロールすることはきわめて重要である。高血圧は日常の話題になるほどに非常に身近な病気であり、治療方法も確立している。にもかかわらず、未治療や治療目標未達成の者が多く存在する。医師のみならず広く医療・介護・福祉関係従事者は現在の高血圧管理指針となっている高血圧治療ガイドライン2019(JSH2019)の内容を理解し、その方針に準拠した管理を行うことが重要である。(著者抄録)

    その他URL: https://search-tp.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2022&ichushi_jid=J04279&link_issn=&doc_id=20220707360001&doc_link_id=10.11320%2Fningendock.37.7&url=https%3A%2F%2Fdoi.org%2F10.11320%2Fningendock.37.7&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  • 日本における高齢者コホート研究の成果 SONIC研究 健康長寿要因探究のための高齢者長期縦断疫学研究

    神出 計, 樺山 舞, 呉代 華容, 樂木 宏実

    日本老年医学会雑誌   58 ( Suppl. )   62 - 62   2021年05月( ISSN:0300-9173

  • 老年医学の展望 高齢者コホート研究update

    呉代 華容, 神出 計

    日本老年医学会雑誌   58 ( 2 )   183 - 189   2021年04月( ISSN:0300-9173

     詳細を見る

    我が国では未曾有の勢いで高齢化が進行し,世界でも最たる長寿国となった.一方で,医療と社会保障制度を維持していくためには,健康長寿社会の実現が求められている.健やかに老い尊厳ある人生を全うするためには,老年病や老年症候群を発症してからの治療や介護だけでなく予防を第一に推進すべきであり,コホート研究の果たす役割は大きい.本稿では,健康長寿社会を目指すべく実施されている,地域在住高齢者を対象とした国内の地域住民を対象としたコホート研究の一端を紹介しつつ,高齢者コホート研究の特徴や展望について述べた.今後,統合コホートの創出や社会実装に向けたコホート研究のさらなる発展が期待される.(著者抄録)

    その他URL: https://search-tp.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2021&ichushi_jid=J01214&link_issn=&doc_id=20210527160002&doc_link_id=1390569634316499968&url=https%3A%2F%2Fcir.nii.ac.jp%2Fcrid%2F1390569634316499968&type=CiNii&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00003_3.gif

  • 【高血圧診療において高齢者で何を診るか】高齢者高血圧の診断と治療の基本 高齢者高血圧の特徴と血圧測定における注意事項

    呉代 華容, 神出 計

    老年内科   2 ( 1 )   1 - 7   2020年07月( ISSN:2435-1881

講演・口頭発表等

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    日本応用老年学会大会  2023年10月  (一社)日本応用老年学会

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    吉田 寛子, 赤木 優也, 木戸 倫子, 呉代 華容, 赤坂 憲, 山本 浩一, 樂木 宏実, 樺山 舞, 神出 計

    日本高血圧学会総会プログラム・抄録集  2023年09月  (NPO)日本高血圧学会

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    日本高血圧学会総会プログラム・抄録集  2023年09月  (NPO)日本高血圧学会

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    大畑 裕可, 呉代 華容, 樺山 舞, 和田 ありさ, 木戸 倫子, 浅山 敬, 大久保 孝義, 樂木 宏実, 田原 康玄, 神出 計

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    志摩 梓, 呉代 華容, 清原 麻衣子, 木村 隆, 宮松 直美

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    方 聞, 呉代 華容, 樺山 舞, 関口 敏彰, 赤木 優也, 赤坂 憲, 権藤 恭之, 新井 康通, 石崎 達郎, 神出 計

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

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    八田 薫, 呉代 華容, 樺山 舞, 赤坂 憲, 権藤 恭之, 増井 幸恵, 新井 康通, 石崎 達郎, 樂木 宏実, 神出 計

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

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    金城 理子, 呉代 華容, 樺山 舞, 赤坂 憲, 増井 幸恵, 池邉 一典, 石崎 達郎, 権藤 恭之, 樂木 宏実, 神出 計

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

  • 地域在住高齢者における受動喫煙と認知機能の関連の検討(SONIC研究)

    木戸 倫子, 赤木 優也, 権藤 恭之, 呉代 華容, 赤坂 憲, 安元 佐織, 増井 幸恵, 石崎 達郎, 樺山 舞, 神出 計

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

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    森岡 千尋, 村上 尚子, 高井 悠花, 方 聞, 中村 千賀, 矢野 朋子, 奈古 由美子, 呉代 華容, 樺山 舞, 神出 計

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

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    矢野 朋子, 村上 尚子, 高井 悠花, 中村 千賀, 森岡 千尋, 方 聞, 奈古 由美子, 呉代 華容, 樺山 舞, 神出 計

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

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    藤原 菜摘, リ・アア, 呉代 華容, 木戸 倫子, 神出 計, 樺山 舞

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

  • 新型コロナウイルス感染症拡大防止対策のために地域在住高齢者の介護予防活動自粛によって生じた身体機能の変化についての検討

    横山 優夏, 呉代 華容, 樺山 舞, 木戸 倫子, 畑中 裕美, 向井 咲乃, 和田 ありさ, 菊池 健, 百々 孝之, 神出 計

    日本老年医学会雑誌  2023年05月  (一社)日本老年医学会

  • 非肥満者における循環器疾患危険因子の保有が脳血管疾患および虚血性心疾患の新規発症に及ぼす影響 肥満者との比較検討

    久保 心櫻, 辻本 美香, 北川 温子, 呉代 華容, 神出 計, 樺山 舞

    日本循環器病予防学会誌  2023年05月  (一社)日本循環器病予防学会

  • Within-week variability of the home blood pressure in the NOSE study.

    Mio Kubo, Kayo Godai, Mai Kabayama, Arisa Wada, Michiko Kido, Sumiyo Hashimoto, Makiko Higashi, Hiromi Hatanaka, Takeshi Kikuchi, Takayuki Dodo, Yasuharu Tabara, Kei Asayama, Takayoshi Ohkubo, Hiromi Rakugi, Kei Kamide

    Blood pressure monitoring  2022年12月 

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    池田 明日香, 藤井 誠, 大野 ゆう子, Li Yaya, 中村 佑子, 呉代 華容, 神出 計, 樺山 舞

    医療情報学連合大会論文集  2022年11月  (一社)日本医療情報学会

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    藤井 誠, 大野 ゆう子, 池田 明日香, 呉代 華容, Li Yaya, 中村 祐子, 神出 計, 樺山 舞

    医療情報学連合大会論文集  2022年11月  (一社)日本医療情報学会

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    中村 祐子, 樺山 舞, 呉代 華容, 赤坂 憲, 権藤 恭之, 新井 康通, 増井 幸恵, 石崎 達郎, 樂木 宏実, 神出 計

    日本老年医学会雑誌  2022年10月  (一社)日本老年医学会

  • 地域在住高齢者における経済状況別に検討した人のつながりと認知機能との関連

    野上 素子, 樺山 舞, 呉代 華容, 赤坂 憲, 池邉 一典, 安元 佐織, 石崎 達郎, 権藤 恭之, 樂木 宏実, 神出 計

    日本老年医学会雑誌  2022年10月  (一社)日本老年医学会

  • 能勢町の通いの場における地域包括による支援と参加者のフレイルの実態

    畑中 裕美, 樺山 舞, 木村 ありさ, 橋本 澄代, 吉田 寛子, 中村 祐子, 小林 慶吾, 呉代 華容, 菊池 健, 神出 計

    日本老年医学会雑誌  2022年10月  (一社)日本老年医学会

  • 能勢町保健事業への参加経路の年代別特徴 新型コロナワクチン接種会場における取組

    東 万紀子, 樺山 舞, 木村 ありさ, 橋本 澄代, 木戸 倫子, 呉代 華容, 菊池 健, 疋田 晃浩, 田原 康玄, 神出 計

    日本老年医学会雑誌  2022年10月  (一社)日本老年医学会

  • 訪問診療を受ける在宅療養高齢者における多剤併用と療養中イベントの関連要因の検討 OHCARE研究

    村上 尚子, 大道 友貴, 糀屋 絵理子, 中村 千賀, 矢野 朋子, 奈古 由美子, 呉代 華容, 樺山 舞, 樂木 宏実, 神出 計

    日本老年医学会雑誌  2022年10月  (一社)日本老年医学会

  • NDBデータを用いた市町村国保における糖尿病性腎症重症化予防プログラム効果の検討

    池田 明日香, 藤井 誠, 大野 ゆう子, Li Yaya, 中村 祐子, 呉代 華容, 神出 計, 樺山 舞

    日本公衆衛生学会総会抄録集  2022年09月  日本公衆衛生学会

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    藤井 誠, 大野 ゆう子, 池田 明日香, Li Yaya, 中村 祐子, 呉代 華容, 神出 計, 樺山 舞

    日本公衆衛生学会総会抄録集  2022年09月  日本公衆衛生学会

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    藤原 菜摘, 木戸 倫子, 呉代 華容, 石月 眞名, 神出 計, 樺山 舞

    日本公衆衛生学会総会抄録集  2022年09月  日本公衆衛生学会

  • 長期家庭血圧測定における週内・季節変動の特徴 能勢健康長寿研究

    久保 心櫻, 呉代 華容, 樺山 舞, 和田 ありさ, 木戸 倫子, 浅山 敬, 大久保 孝義, 田原 康玄, 神出 計

    日本高血圧学会臨床高血圧フォーラムプログラム・抄録集  2022年06月  (NPO)日本高血圧学会

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    水野 稔基, 呉代 華容, 樺山 舞, 井坂 昌明, 権藤 恭之, 小川 まどか, 池邉 一典, 増井 幸恵, 新井 康通, 石崎 達郎, 樂木 宏実, 神出 計

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    村上 尚子, 高井 悠花, 大道 友貴, 中村 千賀, 矢野 朋子, 奈古 由美子, 呉代 華容, 樺山 舞, 楽木 宏実, 神出 計

    日本老年医学会雑誌  2022年05月  (一社)日本老年医学会

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    吉田 寛子, 樺山 舞, 呉代 華容, 赤坂 憲, 山本 浩一, 池邉 一典, 安元 佐織, 権藤 恭之, 樂木 宏実, 神出 計

    日本循環器病予防学会誌  2022年05月  (一社)日本循環器病予防学会

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    小林 慶吾, 呉代 華容, 樺山 舞, 赤坂 憲, 権藤 恭之, 増井 幸恵, 新井 康通, 石崎 達郎, 楽木 宏実, 神出 計

    日本老年医学会雑誌  2022年05月  (一社)日本老年医学会

  • 地域在住高齢者における糖尿病とアテローム性動脈硬化症の関連性 SONIC研究

    菊池 晴奈, 呉代 華容, 樺山 舞, 赤坂 憲, 池邉 一典, 新井 康通, 石崎 達郎, 権藤 恭之, 楽木 宏実, 神出 計

    日本老年医学会雑誌  2022年05月  (一社)日本老年医学会

  • 地域在住高齢者における睡眠薬使用・睡眠状態とフレイルの関連性は年代別で異なる SONIC研究

    水野 稔基, 呉代 華容, 樺山 舞, 権藤 恭之, 小川 まどか, 増井 幸恵, 新井 康通, 石崎 達郎, 楽木 宏実, 神出 計

    日本老年医学会雑誌  2022年05月  (一社)日本老年医学会

  • 地域在住高齢者における疾患への罹患と主観的健康感の関連についての検討

    田村 彩乃, 樺山 舞, 呉代 華容, 赤坂 憲, 権藤 恭之, 増井 幸恵, 新井 康通, 石崎 達郎, 楽木 宏実, 神出 計

    日本老年医学会雑誌  2022年05月  (一社)日本老年医学会

  • 地域在住高齢者における70歳以降の就労に関連する要因についての男女別検討

    久保 心櫻, 呉代 華容, 樺山 舞, 赤坂 憲, 安元 佐織, 増井 幸恵, 石崎 達郎, 権藤 恭之, 楽木 宏実, 神出 計

    日本老年医学会雑誌  2022年05月  (一社)日本老年医学会

  • 在宅医療受給者における訪問看護利用者の特性の検討と緊急時における訪問看護ステーションの役割 OHCARE研究

    高井 悠花, 村上 尚子, 奈古 由美子, 中村 千賀, 矢野 朋子, 糀屋 絵理子, 呉代 華容, 木戸 倫子, 樺山 舞, 神出 計

    日本老年医学会雑誌  2022年05月  (一社)日本老年医学会

  • 健康寿命延伸に向けた家庭血圧測定による地域介入 地域コホートの立ち上げ 能勢健康長寿研究(のせけん)

    樺山 舞, 和田 ありさ, 呉代 華容, 浅山 敬, 大久保 孝義, 樂木 宏実, 田原 康玄, 神出 計

    日本循環器病予防学会誌  2022年05月  (一社)日本循環器病予防学会

  • 地域在住高齢者における年代別体重減少の要因

    矢野 朋子, 呉代 華容, 樺山 舞, 増井 幸恵, 石崎 達郎, 権藤 恭之, 神出 計

    日本公衆衛生学会総会抄録集  2021年11月  日本公衆衛生学会

  • 地域在住高齢者において骨関節疾患が将来の身体的フレイルへの進展に及ぼす影響の年代別の検討

    大畑 裕可, 樺山 舞, 呉代 華容, 赤坂 憲, 山本 浩一, 杉本 研, 池邉 一典, 増井 幸恵, 権藤 恭之, 石崎 達郎, 楽木 宏実, 神出 計

    日本サルコペニア・フレイル学会雑誌  2021年10月  (一社)日本サルコペニア・フレイル学会

  • 家庭血圧測定による健康寿命延伸に対する効果検証の試み 能勢健康長寿研究(のせけん)について

    木村 ありさ, 樺山 舞, 呉代 華容, 橋本 澄代, 東 万紀子, 吉村 哲哉, 福原 美貴子, 藤原 伸祐, 田原 康玄, 神出 計

    日本老年医学会雑誌  2021年05月  (一社)日本老年医学会

  • Associations among anxiety, risk perception, preventive behaviors, and personality in Japanese older adults aged 78 to 99 years during the COVID-19 pandemic

    Hiroyuki Muto, Yasuyuki Gondo, Ayaka Kasuga, Takeshi Nakagawa, Yoshiko Ishioka, Wataru Onoguchi, Akari Kikuchi, Hiroki Inagaki, Madoka Ogawa, Noriko Hori, Yukie Masui, Hwang Choe, Yutian Cheng, Kiyoaki Matsumoto, Saori Yasumoto, Mai Kabayama, Kayo Godai, Kazunori Ikebe, Kei Kamide, Tatsuro Ishizaki

    PsyArXiv  2021年03月 

  • 未治療高血圧者への健診現場での紹介状発行が翌年のIII度高血圧を抑制する効果 職域クラスターランダム化比較試験の事後解析

    志摩 梓, 辰巳 友佳子, 有馬 久富, 三浦 克之, 河津 雄一郎, 森野 亜弓, 大久保 孝義, 木村 隆, 呉代 華容, 宮松 直美

    日本循環器病予防学会誌  2020年11月  (一社)日本循環器病予防学会

  • 地域在住高齢者における年代別体重減少と6年後調査脱落との関連

    矢野 朋子, 呉代 華容, 樺山 舞, 神出 計

    日本公衆衛生学会総会抄録集  2020年10月  日本公衆衛生学会

  • 地域在住高齢者における体格指数の変化で分類した肥満と頸動脈硬化の縦断的検討 SONIC研究

    車 千鶴, 樺山 舞, 呉代 華容, 赤木 優也, 赤坂 憲, 杉本 研, 池邉 一典, 権藤 恭之, 樂木 宏実, 神出 計

    日本老年医学会雑誌  2020年10月  (一社)日本老年医学会

  • 地域在住の高齢者ならびに超高齢者の身体機能と要介護認定との関連 SONIC研究

    シートゥムンクウィアラユ, 樺山 舞, 呉代 華容, クリンプタンノンラツク, 杉本 研, 石崎 達郎, 権藤 恭之, 樂木 宏実, 下方 浩史, 神出 計

    日本老年医学会雑誌  2020年07月  (一社)日本老年医学会

  • 地域在住高齢者における塩分チェックシートで評価した塩分摂取量と血圧値の関連の検討

    吉田 寛子, 樺山 舞, 呉代 華容, 赤坂 憲, 杉本 研, 池邉 一典, 安元 佐織, 権藤 恭之, 樂木 宏実, 神出 計

    日本老年医学会雑誌  2020年07月  (一社)日本老年医学会

  • The Association between heart diseases, social factors, and physical frailty in community-dwelling older populations: SONIC study

    Kei Kamide, Nonglak Klinpudtan, Mai Kabayama, Yasuyuki Gondo, Yukie Masui, Yuya Akagi, Werayuth Srithum, Eri Kiyoshige, Kayo Godai, Ken Sugimoto, Hiroshi Akasaka, Yoichi Takami, Yasushi Takeya, Koichi Yamamoto, Kazunori Ikebe, Saori Yasumoto, Madoka Ogawa, Hiroki Inagaki, Tatsuro Ishizaki, Hiromi Rakugi

    2020年02月  Research Square

     詳細を見る

    <title>Abstract</title> Objectives Physical frailty is geriatric syndrome and can increase the risk of adverse outcome in the older population. Heart diseases are associated with physical frailty but a few studies in community-dwelling old population. Therefore the aim of this study was to examine the association between heart diseases, social factors, and physical frailty in community-dwelling older populations including the oldest old people. Methods The cross-sectional study included 1882 participants in community-dwelling older and oldest-old people in three age groups: 73 (±1), 83 (±1), and 93(±1) from both urban and rural areas of Japan. Questionnaires on medical history, psycho-social factors, blood samples, physical examinations, the hand grip strength test, and gait speed were measured at the venue. Physical frailty was defined based on a slow gait speed or weak grip strength. Heart diseases were assessed by self-reported questionnaires. Social interaction was based on the frequency of going outdoors and direct social contact. Analyses were conducted mainly using multiple logistic regression with adjustments for physical frailty risk factors. Results Heart disease subjects had a higher prevalence of physical frailty than those without heart disease (slow gait speed: 69.6 vs. 56.2%, p&lt;.001; slow gait speed or weak grip strength: 80 vs. 69.6%, p=.002). After adjusting the covariate factors, heart diseases were associated with a slow gait speed (OR=1.5; 95%CI: 1.03-2.20, p=.035). Social interaction was associated with a slow gait speed (frequency of going outdoors: OR=0.87, 95%CI 0.79-0.9, p=.008; frequency of direct social contact: OR=0.88, 95%CI 0.82-0.95, p=.001), a weak grip strength (frequency of going outdoors: OR=0.86, 95%CI 0.77-0.96, p=.005), and with physical frailty (frequency of going outdoors: OR=0.84, 95%CI 0.75-0.94, p=.002; frequency of direct social contact: OR=0.89, 95%CI 0.82-0.97, p=.007). Living alone and frequency of direct social contact were associated with physical frailty among heart disease patients. Conclusions Our findings indicate that in community-dwelling older people, heart diseases and social interaction were associated with physical frailty. Older people with heart disease, those living alone and the frequency of direct social contact were associated with physical frailty. Future research must involve a longitudinal study to clarify the causal relationship.

    その他リンク: https://www.researchsquare.com/article/rs-13772/v1.html

  • 地域在住高齢者における上腕血圧の左右差と動脈硬化との関連についての検討

    廣瀬 充登, 樺山 舞, 呉代 華容, 赤木 優也, 赤坂 憲, 山本 浩一, 杉本 研, 楽木 宏実, 神出 計

    日本高血圧学会総会プログラム・抄録集  2019年10月  (NPO)日本高血圧学会

  • 地域在住の超高齢者における血圧日間変動と認知機能との関連 SONIC研究からの知見

    呉代 華容, 樺山 舞, 赤坂 憲, 山本 浩一, 杉本 研, 佐藤 倫広, 浅山 敬, 大久保 孝義, 楽木 宏実, 神出 計

    日本高血圧学会総会プログラム・抄録集  2019年10月  (NPO)日本高血圧学会

  • 現代の我が国の一般地域住民における家庭血圧の現状 Modern Database on Ambulatory and Self-measured home blood pressure(MDAS)

    浅山 敬, 田原 康玄, 大石 絵美, 坂田 智子, 久松 隆史, 呉代 華容, 樺山 舞, 辰巳 友佳子, 秦 淳, 菊谷 昌浩, 神出 計, 三浦 克之, 二宮 利治, 大久保 孝義

    日本高血圧学会総会プログラム・抄録集  2019年10月  (NPO)日本高血圧学会

  • 飲酒習慣を有する男性高血圧患者のアルコール摂取量の減少と早朝家庭血圧の関連 OSAKE研究

    赤木 優也, 樺山 舞, 呉代 華容, 玉谷 実智夫, 冨田 純, 滝内 伸, 山本 浩一, 杉本 研, 楽木 宏実, 神出 計

    日本高血圧学会総会プログラム・抄録集  2019年10月  (NPO)日本高血圧学会

  • 飲酒習慣を有する高血圧患者への保健指導の有効性に関する多施設前向きランダム化比較試験(OSAKE研究)

    樺山 舞, 赤木 優也, 呉代 華容, 玉谷 実智夫, 冨田 純, 滝内 伸, 山本 浩一, 杉本 研, 楽木 宏実, 神出 計

    日本高血圧学会総会プログラム・抄録集  2019年10月  (NPO)日本高血圧学会

  • 禁煙継続者及び禁煙開始者の耐糖能障害発症リスク 職域コホートにおける平均7年間の追跡

    東 さおり, 志摩 梓, 呉代 華容, 辰巳 友佳子, 森野 亜弓, 河津 雄一郎, 宮松 直美

    日本循環器病予防学会誌  2019年04月  (一社)日本循環器病予防学会

  • The association of the measuring blood pressure at home with cognitive functioning among community-dwelling elderly.

    Godai K, Kabayama M, Yamamoto K, Sugimoto K, Arai Y, Ishizaki T, Ikebe K, Gondo Y, Rakugi H, Kamide K

    2019年01月 

  • 地域在住の超高齢者における血圧特性 随時血圧と家庭血圧との違い SONIC研究からの知見

    呉代 華容, 樺山 舞, 赤坂 憲, 山本 浩一, 杉本 研, 佐藤 倫広, 浅山 敬, 大久保 孝義, 樂木 宏実, 神出 計

    日本高血圧学会総会プログラム・抄録集  2018年09月  (NPO)日本高血圧学会

  • ALCOHOL CONSUMPTION AND PSYCHOLOGICAL DISTRESS IN HEALTHY JAPANESE RESIDENTS: THE KOBE STUDY

    K. Godai, N. Miyamatsu, A. Higashiyama, S. Kubo, Y. Nishida, D. Sugiyama, Y. Nii, Y. Tatsumi, T. Nishikawa, T. Okamura

    ALCOHOL AND ALCOHOLISM  2017年10月  OXFORD UNIV PRESS

  • 特定保健指導の積極的支援該当者における睡眠の質とHbA1c値改善との関連

    呉代 華容, 神出 計, 樺山 舞, 奥田 奈賀子, 中村 幸志, 渡邉 至, 栗林 徹, 板井 一好, 由田 克士, 三浦 克之, 岡山 明

    日本公衆衛生学会総会抄録集  2017年10月  日本公衆衛生学会

  • 診察室血圧は自由行動した血圧を過小評価する:仮面高血圧研究

    呉代華容, 神出 計

    血圧  2017年10月 

  • 若年代層ほど禁煙失敗リスクが高い 職域コホートにおける5年間の追跡

    志摩 梓, 三浦 克之, 森野 亜弓, 河津 雄一郎, 呉代 華容, 辰巳 友佳子, 東 さおり, 宮松 直美

    日本アルコール・薬物医学会雑誌  2017年08月  日本アルコール・アディクション医学会

  • 男女別、飲酒状況が精神的健康状態に与える影響 神戸研究

    呉代 華容, 宮松 直美, 東山 綾, 久保 佐智美, 西田 陽子, 杉山 大典, 二井 悠希, 辰巳 友佳子, 西川 智文, 岡村 智教

    日本アルコール・薬物医学会雑誌  2017年08月  日本アルコール・アディクション医学会

  • 能動喫煙・受動喫煙が精神的健康状態に与える影響

    二井 悠希, 宮松 直美, 東山 綾, 久保 佐智美, 西田 陽子, 杉山 大典, 呉代 華容, 辰巳 友佳子, 西川 智文, 岡村 智教

    日本アルコール・薬物医学会雑誌  2017年08月  日本アルコール・アディクション医学会

  • Effects of health-prone behavior concerning breast cancer on blood pressure control in hypertensives

    N. Miyamatsu, A. Shima, K. Godai, H. Tanaka, E. Mekata, Y. Kawatsu, Y. Matsumura, T. Nishikawa, T. Okamura

    EUROPEAN JOURNAL OF PUBLIC HEALTH  2016年11月  OXFORD UNIV PRESS

  • インスリン療法中の糖尿病患者における軽症低血糖頻度とその後の重症低血糖との関連

    園田奈央, 森本明子, 卯木智, 森野勝太郎, 関根理, 根本憲一, 呉代華容, 前川聡, 宮松直美

    糖尿病(Web)  2016年 

  • 職域がん検診調査(第1報) 調査概要、大腸がん検診結果の認識と精密検査受診状況

    呉代 華容, 志摩 梓, 河津 雄一郎, 辰巳 友佳子, 森本 明子, 宮松 直美

    日本公衆衛生学会総会抄録集  2015年10月  日本公衆衛生学会

  • 職域がん検診調査(第2報) 胃がんリスク検診に関する自己認識と精密検査受診状況

    志摩 梓, 呉代 華容, 辰巳 友佳子, 河津 雄一郎, 森本 明子, 宮松 直美

    日本公衆衛生学会総会抄録集  2015年10月  日本公衆衛生学会

  • 糖尿病患者における喫煙状況と軽度認知機能低下との関連

    園田奈央, 森本明子, 卯木智, 呉代華容, 森野勝太郎, 関根理, 根本憲一, 前川聡, 宮松直美

    日本循環器病予防学会誌  2015年06月 

  • 職域高血圧者における降圧剤処方間隔と3年後の血圧コントロールの関連

    志摩 梓, 辰巳 友佳子, 呉代 華容, 森本 明子, 河津 雄一郎, 石崎 達郎, 岡村 智教, 宮松 直美

    日本循環器病予防学会誌  2015年06月  (一社)日本循環器病予防学会

  • 女性就労者におけるBody mass index階層と転倒経験の関連について

    志摩 梓, 河津 雄一郎, 呉代 華容, 荻田 美穂子, 森本 明子, 片寄 亮, 宮松 直美

    日本公衆衛生学会総会抄録集  2014年10月  日本公衆衛生学会

  • Synergistic effect of the combination of mass media and distribution media on improvement of knowledge about early stroke symptoms

    N. Miyamatsu, A. Morino, K. Miura, K. Godai, A. Morimoto, Y. Murakami, N. Takashima, Y. Kita, K. Nozaki

    INTERNATIONAL JOURNAL OF STROKE  2014年10月  WILEY-BLACKWELL

  • Association of Early Hospital Arrival with Functional Prognosis at Discharge in Ischemic Stroke

    Morino, Ayumi, Morimoto, Akiko, Ichiura, Kayoko, Katayose, Ryo, Sonoda, Nao, Godai, Kayo, Miyamatsu, Naomi

    CEREBROVASCULAR DISEASES  2014年09月  KARGER

  • 喫煙の有無による,循環器リスク因子集積がその後9年間の外来医療費に及ぼす影響

    志摩梓, 呉代華容, 森本明子, 辰巳友佳子, 河津雄一郎, 石崎達郎, 岡村智教, 宮松直美

    日本循環器病予防学会誌  2014年07月 

  • 就労者における健康習慣の実施数と9年後の高血圧の関連の検討

    志摩梓, 呉代華容, 森本明子, 辰巳友佳子, 河津雄一郎, 宮松直美

    日本産業衛生学会講演集(CD-ROM)  2014年05月 

  • 一大学病院外来通院中の糖尿病患者の低血糖の実態

    園田奈央, 森本明子, 卯木智, 森野勝太郎, 関根理, 前川聡, 小林康子, 呉代華容, 森野亜弓, 宮松直美

    糖尿病  2014年04月 

  • 脳梗塞患者の発症―来院時間が退院時の機能維特に及ぼす影響

    森野亜弓, 森本明子, 一浦嘉代子, 荻野麻子, 河上圭代, 北脇友美, 西田浩美, 脇千代, 本郷美都里, 植西治子, 片寄亮, 園田奈央, 呉代華容, 宮松直美

    J Epidemiol  2014年01月 

  • 職域集団における糖尿病型ごとの睡眠時間とHbA<sub>1c</sub>値との関連

    呉代華容, 志摩梓, 河津雄一郎, 森本明子, 園田奈央, 森野亜弓, 宮松直美

    J Epidemiol  2014年01月 

  • 一企業就労女性の閉経の有無によるBMIと高血圧症の関連の横断的評価

    片寄亮, 志摩梓, 志摩梓, 河津雄一郎, 森本明子, 呉代華容, 森野亜弓, 園田奈央, 一浦嘉代子, 宮松直美

    Journal of Epidemiology  2014年 

  • Attitude to an Ambulance Call and Knowledge About Early Symptoms of Stroke Among Japanese General Population

    N. Miyamatsu, K. Nozaki, K. Miura, A. Morino, A. Morimoto, R. Katayose, K. Godai, N. Sonoda, Y. Murakami, Y. Kita, N. Takashima, A. Kashiwagi

    CEREBROVASCULAR DISEASES  2013年  KARGER

  • Relationship Between Knowledge of Early Stroke Symptoms and Planned Response to Each Symptom Among a General Japanese Population

    A. Morimoto, N. Miyamatsu, K. Nozaki, K. Miura, A. Morino, R. Katayose, K. Godai, N. Sonoda, Y. Murakami, Y. Kita, N. Takashima, A. Kashiwagi

    CEREBROVASCULAR DISEASES  2013年  KARGER

  • Nurses' Practices of Care for Patients with Acute Stroke: Differences among Nursing Units

    Katayose, Ryo, Ogita, Mihoko, Morimoto, Akemi, Morimoto, Akiko, Ichiura, Kayoko, Morino, Ayumi, Sonoda, Nao, Godai, Kayo, Ogawa, Nozomi, Miyamatsu, Naomi

    CEREBROVASCULAR DISEASES  2013年  KARGER

  • Knowledge About Early Symptoms of Stroke Among a Japanese Population

    Morino, Ayumi, Miyamatsu, Naomi, Nozaki, Kazuhiko, Miura, Katsuyuki, Morimoto, Akiko, Katayose, Ryo, Sonoda, Nao, Godai, Kayo, Murakami, Yoshitaka, Kita, Yoshikuni, Takashima, Naoyuki, Kashiwagi, Atsunori

    CEREBROVASCULAR DISEASES  2013年  KARGER

  • Effects of Intensive and Moderate Public Education on Knowledge about Risk Factors of Stroke among a General Japanese Population

    Kayo Godai, Naomi Miyamatsu, Tomonori Okamura, Hirofumi Nakayama, Akiko Morimoto, Kazunori Toyoda, Kazuo Suzuki, Akihiro Toyota, Takashi Hata, Takenori Yamaguchi

    CEREBROVASCULAR DISEASES  2013年  KARGER

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