Updated on 2026/02/25

写真a

 
TAMAI KOJI
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Lecturer
School of Medicine Department of Medical Science
Title
Lecturer
Affiliation
Institute of Medcine
Affiliation campus
Abeno Campus

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Lecturer  2025.04 - Now

  • School of Medicine Department of Medical Science 

    Lecturer  2025.04 - Now

Degree

  • 博士（医学） （ Osaka City University ）

Research Areas

  • Life Science / Orthopedics  / Artificial intelligence

  • Life Science / Orthopedics  / Fraility

  • Life Science / Orthopedics  / Spine surgery

  • Life Science / Orthopedics  / Orthopaedic Surgery

Research Interests

  • Orthopaedic Surgery, Musculoskeletal System, Spine Surgery, Spine, Geriatrics, Frailty, Artificial Intelligence

Professional Memberships

  • 日本脊椎脊髄病学会

    2012.04 - Now

  • 日本整形外科学会

    2010.04 - Now

  • 日本インストゥルメンテーション学会

    2018.04 - Now

  • 中部日本整形災害外科学会

    2010.04 - Now

  • North America Spine Society

    2016.04 - Now

  • SPINE20

    2019.01 - Now

  • Cervical Spine Research Society

    2018.04 - Now

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Committee Memberships (off-campus)

  • International Strategic Growth Committee member  

    2024.09 - Now 

  • 日本脊椎脊髄病学会   評議員  

    2024.04 - Now 

  • 日本脊椎脊髄病学会   社会保険等システム検討委員会委員  

    2024.04 - Now 

  • 日本脊椎脊髄病学会   英文誌編集委員会委員  

    2024.04 - Now 

  • 日本脊椎脊髄病学会   国際委員会委員  

    2023.10 - Now 

  • SPINE20   Chair of Scientific Committee  

    2023.09 - Now 

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Awards

  • 日本整形外科学会奨励賞

    2026   日本整形外科学会  

  • JOS Associated Editor Recommended Reviewers

    2025  

  • Teacher of the year 2024

    2024   大阪公立大学医学部医学科  

  • 仁澪奨励賞

    2024   仁澪会  

  • 最優秀Discusser賞

    2023.08   Japan Association of Spine Surgeons with Ambition  

  • 最優秀演題賞

    2021   AO spine Japan congress/conference  

  • 20 under 40 award

    2021  

  • 若手研究者奨励賞

    2020   大阪市立大学  

  • 香港骨化学会トラベリングフェロー

    2020   日本整形外科学会  

  • 台湾脊椎外科学会トラベリングフェロー

    2020   日本脊椎脊髄病学会  

  • アジアトラベリングフェロー

    2019   日本脊椎脊髄病学会  

  • 同門会賞

    2018   大阪市立大学整形外科同門会  

  • アルファテック・パシフィック奨励賞

    2015   整形災害外科学研究助成財団  

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Job Career (off-campus)

  • 大阪市立総合医療センター

    2012.04 - 2013.03

  • 清恵会病院

    2008.04 - 2012.03

Papers

  • Efficacy of Chemonucleolysis With Condoliase Versus Minimally Invasive Discectomy for Lumbar Disc Herniation: A Propensity Score-Matched Retrospective Cohort Study

    Uematsu M.

    Global Spine Journal   16 ( 2 )   1221 - 1231   2026.03（ ISSN:21925682 ）

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  • Changes in performance status and predictive factors for poor improvement following surgery for spinal metastasis: a nationwide multicenter prospective cohort study

    Suzuki A.

    Spine Journal   26 ( 2 )   386 - 399   2026.02（ ISSN:15299430 ）

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  • Risk factors for cage subsidence following anterior-posterior spinal fixation in osteoporotic vertebral fractures: a multicenter retrospective study.

    Kinoshita Y, Takahashi S, Yasuda H, Terakawa M, Konishi S, Kato M, Toyoda H, Suzuki A, Tamai K, Yabu A, Sawada Y, Iwamae M, Okamura Y, Kobayashi Y, Uematsu M, Taniwaki H, Nakamura H, Terai H

    Asian spine journal   2026.01（ ISSN:1976-1902 ）

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  • Deep learning algorithm for identifying osteopenia/osteoporosis using cervical radiography

    Tamai K.

    Scientific Reports   15 ( 1 )   25274   2025.12

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  • Characterizing stroke-related cellular changes in the surviving neurons of mouse ischemic stroke

    Ikegami T.

    Neurochemistry International   191   106086   2025.12（ ISSN:01970186 ）

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  • Effect of Preoperative Nutritional Status on Postoperative Clinical Outcomes of Patients With Metastatic Spinal Tumors

    Kawai M.

    Spine   50 ( 22 )   1571 - 1580   2025.11（ ISSN:03622436 ）

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  • Canadian Spine Society: 25th Annual Scientific Conference, February 25 to 28, 2025, Fairmont Le Manoir Richelieu, La Malbaie, Charlevoix, Que., Canada

    Chan V.

    Canadian Journal of Surgery Journal Canadien De Chirurgie   68 ( 6suppl3 )   S58 - S132   2025.11（ ISSN:0008-428X ）

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  • Predicting osteoporosis-related complications in lumbar spine surgery using Hounsfield unit and vertebral bone quality scores: A 5-Year follow-up study with principal component analysis insights

    Kinoshita Y.

    European Spine Journal   34 ( 11 )   5148 - 5156   2025.11（ ISSN:09406719 ）

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  • Machine Learning-Based Prediction of Quality of Life Improvement After Surgery for Spinal Metastases

    Kitagawa K.

    Spine   50 ( 20 )   1410 - 1419   2025.10（ ISSN:03622436 ）

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  • Characteristics and Clinical Outcomes of Transition from Conservative Therapy to Surgical Intervention in Older Patients with Cervical Spinal Cord Injury without Major Bone Injury: A Nationwide Retrospective Study

    Yokogawa Noriaki, Sasagawa Takeshi, Hayashi Hiroyuki, Demura Satoru, Nakashima Hiroaki, Segi Naoki, Watanabe Kota, Nori Satoshi, Funayama Toru, Eto Fumihiko, Nakajima Hideaki, Furuya Takeo, Yunde Atsushi, Terashima Yoshinori, Hirota Ryosuke, Yamada Tomohiro, Hasegawa Tomohiko, Suzuki Hidenori, Imajo Yasuaki, Kawaguchi Kenichi, Haruta Yohei, Tonomura Hitoshi, Sakata Munehiro, Terai Hidetomi, Tamai Koji, Inoue Gen, Ikegami Shota, Akeda Koji, Nakanishi Kazuo, Uei Hiroshi, Funao Haruki, Oshima Yasushi, Yoshii Toshitaka, Hashimoto Ko, Iizuka Yoichi, Kiyasu Katsuhito, Ishihara Masayuki, Kaito Takashi, Okada Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   9 ( 5 )   530 - 538   2025.09（ eISSN:2432261X ）

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    <p>Introduction: Cervical spinal cord injury (CSCI) without major bone injury is increasing among older adults, particularly in aging societies like Japan. The optimal treatment strategies remain unclear, with conservative therapy often preferred, especially for older patients. However, surgery is frequently necessary due to poor improvement or progression of paralysis during conservative treatment. This study investigated the characteristics and outcomes of older patients with CSCI without major bone injury who transitioned from conservative treatment to surgery.</p><p>Methods: This nationwide, retrospective study examined data from patients aged ≥65 years with CSCI without major bone injury. The patients were categorized into 3 groups: conservative treatment, planned surgery, and those who switched from conservative treatment to surgery. The study aimed to identify the risk factors for conservative therapy failure that necessitate surgical intervention and to compare the outcomes between patients who had planned surgery and those who required surgery after conservative management failed.</p><p>Results: Among 615 patients, 422 (68.6%) received conservative treatment, 193 (31.4%) had planned surgery, and 116 (18.9%) transitioned from conservative to surgical treatment. Transition to surgery was mainly due to poor improvement or progression of neurological deficits. Significant risk factors for transitioning to surgery included younger age, presence of ossification of the posterior longitudinal ligament, and spinal cord signal changes on magnetic resonance imaging. Comparative analysis showed no significant differences in neurological outcomes between patients who had surgery as planned and those who required surgery after failed conservative treatment.</p><p>Conclusions: A significant proportion of older patients with CSCI without major bone injury who were initially managed conservatively eventually required surgery due to insufficient neurological improvement. The outcomes of patients who transitioned to surgery were similar to those who had surgery as initially planned, indicating that careful monitoring of conservative treatment followed by surgery, if necessary, may be an effective approach.</p>

    DOI： 10.22603/ssrr.2024-0291

    PubMed

    CiNii Research

  • Learning curve in the introduction of endoscopic laminectomy

    AKAI Yasuaki

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   68 ( 5 )   655 - 656   2025.09（ ISSN:00089443 ） （ eISSN:13490885 ）

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  • Impact of Antiplatelet Medication Continuation on Surgical Outcomes after Minimally Invasive Posterior Lumbar Decompression Surgery: Retrospective Cohort Study

    Sawada Y.

    Global Spine Journal   15 ( 7 )   3065 - 3072   2025.09（ ISSN:21925682 ）

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  • Characteristics and Clinical Outcomes of Transition from Conservative Therapy to Surgical Intervention in Older Patients with Cervical Spinal Cord Injury without Major Bone Injury: A Nationwide Retrospective Study(タイトル和訳中)

    Yokogawa Noriaki, Sasagawa Takeshi, Hayashi Hiroyuki, Demura Satoru, Nakashima Hiroaki, Segi Naoki, Watanabe Kota, Nori Satoshi, Funayama Toru, Eto Fumihiko, Nakajima Hideaki, Furuya Takeo, Yunde Atsushi, Terashima Yoshinori, Hirota Ryosuke, Yamada Tomohiro, Hasegawa Tomohiko, Suzuki Hidenori, Imajo Yasuaki, Kawaguchi Kenichi, Haruta Yohei, Tonomura Hitoshi, Sakata Munehiro, Terai Hidetomi, Tamai Koji, Inoue Gen, Ikegami Shota, Akeda Koji, Nakanishi Kazuo, Uei Hiroshi, Funao Haruki, Oshima Yasushi, Yoshii Toshitaka, Hashimoto Ko, Iizuka Yoichi, Kiyasu Katsuhito, Ishihara Masayuki, Kaito Takashi, Okada Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   9 ( 5 )   530 - 538   2025.09

  • A deep learning-based prediction model for prognosis of cervical spine injury: a Japanese multicenter survey

    Ito S.

    European Spine Journal   34 ( 9 )   3714 - 3723   2025.09（ ISSN:09406719 ）

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  • 内視鏡下椎弓切除術導入におけるラーニングカーブ　UBE/BESS vs.MEL

    赤井 靖明, 加藤 相勲, 玉井 孝司, 高橋 真治, 鈴木 亨暢, 寺井 秀富

    中部日本整形外科災害外科学会雑誌   68 ( 5 )   655 - 656   2025.09（ ISSN:0008-9443 ）

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    腰部脊柱管狭窄症に対し内視鏡下椎弓切除術を施行した67例をUBE/BESS群28例、MEL群39例に分け、ラーニングカーブを比較検討した。その結果、両群のラーニングカーブは類似しており、術後成績も同等であった。本検討ではUBE/BESSを担当した術者は既にMELの手技を習熟していたため、UBE/BESSを早期に習得できた可能性が考えられた。

  • The Risk of Intravenous Cement Leakage and Short-term Outcomes of Selective Cement-augmented Pedicle Screws: A Multicenter Retrospective Study

    Takahashi S.

    Clinical Spine Surgery   38 ( 7 )   E419 - E424   2025.08（ ISSN:23800186 ）

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  • Effect of romosozumab administration on proximal junctional kyphosis in corrective spinal fusion surgery

    Sawada Y.

    Spine Journal   25 ( 6 )   1218 - 1228   2025.06（ ISSN:15299430 ）

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  • Clinical and Economic Outcomes of Intradiscal Injection of Condoliase for a Treatment of Lumbar Disc Herniation with Severe Low Back Pain: A Multicenter Study

    Hirai Takashi, Takahashi Takuya, Takahashi Yohei, Watanabe Kota, Banno Tomohiro, Sakaki Kyohei, Arai Yoshiyasu, Takano Yuichi, Eguchi Yawara, Taniguchi Yuki, Maki Satoshi, Aoki Yasuchika, Fujii Shunichi, Sakaeda Kentaro, Matsukura Yu, Akazawa Tsutomu, Minamide Akihito, Nojiri Hidetoshi, Sakai Kenichiro, Kato Satoshi, Tamai Koji, Suzuki Hidekazu, Miyagi Masayuki, Sato Hiroyuki, Yoshii Toshitaka, Yamada Hiroshi, Kaito Takashi, Hiraizumi Yutaka, Yamagata Masatsune, Nakamura Masaya, Hirakawa Akihiro, Hosogane Naofumi, Ohtori Seiji

    Spine Surgery and Related Research   9 ( 3 )   368 - 374   2025.05（ eISSN:2432261X ）

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    <p>Introduction: Chemonucleolysis with condoliase (chondroitin sulfate ABC endolyase) has been widely employed to treat patients with lumbar disc herniation (LDH) in Japan. Although it is an effective and relatively safe treatment for radicular neuropathy in patients with LDH, there have been no reports that investigate how severe low back pain (LBP) changes after condoliase injection. In this multicenter study, the effectiveness of condoliase injection for reducing severe LBP in patients with LDH was evaluated.</p><p>Methods: This retrospective study involved patients treated with intradiscal condoliase injection for LDH at nine participating centers. Patients were diagnosed with subligamentous-type herniation based on pretreatment MRI. Patients with severe LBP (defined as a preinjection numeric rating scale [NRS] for LBP greater than or equal to that for leg pain) were categorized into the LBP group. Demographic data, adverse events, treatment costs, and the NRS for LBP and lower extremity pain were analyzed. A 50% response was defined as ≥50% improvement in the NRS at 1 year postinjection. On the basis of the Pfirman classification, the LBP group was divided into less-degenerative (Grades II and III) and degenerative (Grades IV and V) subgroups.</p><p>Results: Seventy-nine patients were classified into the LBP group. Of these patients, 61 (77.2%) showed a >50% reduction in LBP, and another 61 (77.2%) demonstrated a >50% reduction in lower extremity pain. Improvement of lower limb pain was considerably better in the less-degenerative group than in the degenerative group, whereas that of low back pain was similar between the two subgroups. Medical costs, which include remuneration for injection, drug fees, inpatient costs, and other expenses, were similar between the LBP group and all cases.</p><p>Conclusions: This retrospective multicenter study revealed that patients with LDH with severe LBP frequently experienced improvement in radicular pain and LBP, which is similar to LDH cases without severe LBP.</p>

    DOI： 10.22603/ssrr.2024-0288

    PubMed

    CiNii Research

  • "Koshimagari Exercise" for Adult Spinal Deformity in Older Adults: Assessment of Home-Based Exercise Outcomes in a Prospective Multicenter Study

    Terai Hidetomi, Takahashi Shinji, Hoshino Masatoshi, Taniwaki Hiroshi, Tamai Koji, Ohmine Toshimitsu, Nakatsuchi Tamotsu, Shinbashi Goya, Teraguchi Masatoshi, Minetama Masakazu, Watanabe Kei, Sato Naritoshi, Kitamura Takuya, Kanda Masaru, Tsujio Tadao, Takeuchi Yuichi, Mizouchi Tatsuki, Ishizu Katsuhito, Ebina Toshihito, Muraoka Yasunari, Sodeyama Tomonori, Mikami Hiroshi, Kasukawa Yuji, Hyakumachi Takahiko, Ishida Kazuhiro, Miyagishima Kazufumi, Oishi Yosuke, Yo Kiyonori, Kimura Ryota, Sato Hiromichi, Nagata Keiji, Yamato Yu, Matsudaira Ko, Miyakoshi Naohisa, Matsuyama Yukihiro, Haro Hirotaka, Hashizume Hiroshi, Yamada Hiroshi, Kaito Takashi, Project Committee of the Japanese Society for Spine Surgery and Related Research (JSSR)

    Spine Surgery and Related Research   9 ( 3 )   358 - 367   2025.05（ eISSN:2432261X ）

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    <p>Introduction: Adult spinal deformity (ASD) is prevalent among older adults, considerably affecting their quality of life. Although surgical interventions are effective, they have high complication rates and medical costs. Furthermore, there is a lack of evidence supporting the effectiveness of nonsurgical treatments (e.g., physical therapy) in patients with ASD. This study aimed to investigate the impact of "Koshimagari exercise," a specific home-based exercise regimen designed for patients with ASD, and to evaluate its effects on clinical outcomes in older adults.</p><p>Methods: A total of 144 participants aged 50-80 years with chronic low back pain (LBP) due to spinal deformities were included in this multicenter prospective study. Qualified physiotherapists conducted intervention sessions at the hospital once a week, and self-exercise was performed at home three times a week. After 3 months, the frequency of self-exercise at home increased to four times a week. Clinical evaluations were conducted using the Oswestry Disability Index (ODI), five-level classification system of EuroQol-5 Dimensions (EQ-5D), Japanese edition of Scoliosis Research Society-22r (SRS-22r), and visual analog scale (VAS) for LBP at baseline and 3, 6, and 12 months. Radiographic evaluations were performed in standing and supine positions.</p><p>Results: Of 130 participants who provided written informed consent, 98 completed the 6-month follow-up and were included in the analysis. Significant improvements observed in ODI, EQ-5D, and VAS scores were observed at 3 months, with SRS-22r scores improving throughout the study period. Radiographically, there were significant differences in the sagittal vertical axis and pelvic tilt at 12 months. Sufficient compliance with the self-exercise program was reported by 96%, 86%, and 73% of participants at 3, 6, and 12 months, respectively.</p><p>Conclusions: The "Koshimagari Exercise" program led to significant short-term improvements in health-related quality of life and pain among elderly patients with ASD. This home-based self-exercise program is an excellent nonsurgical treatment option for patients with ASD.</p>

    DOI： 10.22603/ssrr.2024-0273

    PubMed

    CiNii Research

  • 特集 整形外科領域におけるAIの応用 Ⅱ章.AIによる画像診断 1.AI技術を活用した脊椎画像診断

    藪 晋人, 高橋 真治, 玉井 孝司, 星野 雅俊, 寺井 秀富

    整形外科   76 ( 6 )   517 - 523   2025.05（ ISSN:00305901 ） （ eISSN:24329444 ）

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  • 【整形外科領域におけるAIの応用】(II章)AIによる画像診断　AI技術を活用した脊椎画像診断

    藪 晋人, 高橋 真治, 玉井 孝司, 星野 雅俊, 寺井 秀富

    整形外科   76 ( 6 )   517 - 523   2025.05（ ISSN:0030-5901 ）

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    ＜文献概要＞はじめに　本邦において,脊椎疾患は高齢化や生活習慣の変化に伴い,増加傾向にある.働き盛りの年齢層から高齢者にいたるまで幅広くみられ,生活の質の低下や介護リスクの増大を招く要因となる.そのため,適切な治療介入が求められる一方で,診断の質を確保することが喫緊の課題である.中でも,画像診断は診断過程においてきわめて重要な役割を担っているが,その解釈は医師の知識や経験に大きく依存しており,軽微な病変や複雑な構造を正確に読み取るには時間と労力を要する.近年,AIの急速な発展により,医療現場におけるAIの活用が注目されている.特にヒトの視覚を模したアルゴリズムである畳み込みニューラルネットワーク(convolutional neural network:CNN)は物体認識やパターン認識に優れ,画像診断との親和性が高い.CNNによる画像解析のタスクは,大きく「分類」,「検出」,「セグメンテーション」の三つに大別される.分類では画像全体から疾患の有無や種類を判別し,検出では異常部位の位置を特定する.さらに,セグメンテーションでは病変領域をピクセル単位で詳細に抽出する(図1).脊椎外科領域においてもCNNを用いた画像診断モデルの開発がすすめられており,従来の診断精度の向上や医療従事者の負担軽減,ひいては患者への早期対応に寄与することが期待されている.本稿では,日常診療でよく遭遇する脊椎疾患の画像診断におけるAI技術の現状について文献レビューを行い,今後の展望について考察した.

  • 重度腰痛を伴う腰椎椎間板ヘルニアに対する椎間板内コンドリアーゼ注入の臨床的・経済的アウトカム　多施設研究(Clinical and Economic Outcomes of Intradiscal Injection of Condoliase for a Treatment of Lumbar Disc Herniation with Severe Low Back Pain: A Multicenter Study)

    Hirai Takashi, Takahashi Takuya, Takahashi Yohei, Watanabe Kota, Banno Tomohiro, Sakaki Kyohei, Arai Yoshiyasu, Takano Yuichi, Eguchi Yawara, Taniguchi Yuki, Maki Satoshi, Aoki Yasuchika, Fujii Shunichi, Sakaeda Kentaro, Matsukura Yu, Akazawa Tsutomu, Minamide Akihito, Nojiri Hidetoshi, Sakai Kenichiro, Kato Satoshi, Tamai Koji, Suzuki Hidekazu, Miyagi Masayuki, Sato Hiroyuki, Yoshii Toshitaka, Yamada Hiroshi, Kaito Takashi, Hiraizumi Yutaka, Yamagata Masatsune, Nakamura Masaya, Hirakawa Akihiro, Hosogane Naofumi, Ohtori Seiji

    Spine Surgery and Related Research   9 ( 3 )   368 - 374   2025.05

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    腰椎椎間板ヘルニア(LDH)患者にみられる重度腰痛に対する椎間板内コンドリアーゼ注入の有効性を検討した。MRIにて靱帯下型ヘルニアと診断され、重度腰痛を呈するLDH患者79例(男性52例、女性27例、平均44.5±19.4歳)を対象に多施設後ろ向き研究を行い、患者基礎データ、有害事象の発現、治療コスト、腰痛と下肢痛の数値化評価尺度(NRS)を評価した。なお、Pfirman分類をもとに軽度変性群(グレードII・III)と変性群(グレードIV・V)に分けた。腰痛NRSはベースライン時が7.6、12ヵ月後が2.3と減少が認められ、下肢痛NRSも12ヵ月後に著明に減少しており、NRSスコアが50%以上減少したのは腰痛が77.2%、下肢痛が77.2%となっていた。また、Pfirman分類上の軽度変性群と変性群との比較では、腰痛NRSは軽度変性群が7.1から1.9、変性群が7.5から2.3へそれぞれ減少、下肢痛NRSは軽度変性群が6.0から0.8、変性群が6.3から2.1へそれぞれ減少を示し、腰痛NRSの改善度に群間差はなかったが、下肢痛NRSの改善度は軽度変性群の方が有意に良好であった。コンドリアーゼ注入の診療報酬、薬剤費、入院費などを含めた総医療コストは130000円であった。椎間板内コンドリアーゼ注入によってLDH患者の腰痛、下肢痛に有意な改善が得られることが示された。

  • 高齢者の成人脊柱変形における「腰曲がり運動」　前向き多施設研究における在宅運動療法のアウトカム評価("Koshimagari Exercise" for Adult Spinal Deformity in Older Adults: Assessment of Home-Based Exercise Outcomes in a Prospective Multicenter Study)

    Terai Hidetomi, Takahashi Shinji, Hoshino Masatoshi, Taniwaki Hiroshi, Tamai Koji, Ohmine Toshimitsu, Nakatsuchi Tamotsu, Shinbashi Goya, Teraguchi Masatoshi, Minetama Masakazu, Watanabe Kei, Sato Naritoshi, Kitamura Takuya, Kanda Masaru, Tsujio Tadao, Takeuchi Yuichi, Mizouchi Tatsuki, Ishizu Katsuhito, Ebina Toshihito, Muraoka Yasunari, Sodeyama Tomonori, Mikami Hiroshi, Kasukawa Yuji, Hyakumachi Takahiko, Ishida Kazuhiro, Miyagishima Kazufumi, Oishi Yosuke, Yo Kiyonori, Kimura Ryota, Sato Hiromichi, Nagata Keiji, Yamato Yu, Matsudaira Ko, Miyakoshi Naohisa, Matsuyama Yukihiro, Haro Hirotaka, Hashizume Hiroshi, Yamada Hiroshi, Kaito Takashi, Project Comittee of the Japanese Society for Spine Surgery and Related Research(JSSR)

    Spine Surgery and Related Research   9 ( 3 )   358 - 367   2025.05

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    高齢者の成人脊柱変形における「腰曲がり運動」のアウトカムを検討した。脊柱変形による慢性腰痛(LBP)を呈する高齢者130例を対象に多施設前向き研究を行い、認定理学療法士が院内で週1回の運動指導を実施し、さらに在宅で週3回の運動プログラムを継続するよう指導、3ヵ月後に運動頻度を週4回とした。臨床評価項目として、Oswestry障害度指数(ODI)、EQ-5Dスコア、SRS-22r日本語版スコア、腰痛VASスコアをベースライン時と3、6、12ヵ月後に測定し、さらに立位と仰臥位にてX線学的評価を行った。6ヵ月後に評価可能であったのは98例(男性15例、女性83例、平均73.0±5.9歳)であり、平均BMIは23.3、Charlson合併症指数(CCI)は0.5、陳旧性椎体骨折を27%に認めた。ODIはベースライン時が35.3、3ヵ月後が32.3、6ヵ月後が33.0と減少し、EQ-5Dスコアはベースライン時が0.63、3ヵ月後が0.65と有意差が認められたが、6ヵ月後、12ヵ月後ではベースライン時と比較して有意差はなかった。腰痛VASスコアはベースライン時が53.1、3ヵ月後が42.8、6ヵ月後が46.0、12ヵ月後が46.2を示し、SRS-22rスコアは3ヵ月後に改善していた。また、X線学的パラメータに関してSVAとPTは12ヵ月後にベースライン時と比較して有意差が認められ、12ヵ月後の運動療法のコンプライアンスはexcellentが33%、goodが40%、fairが27%を示していた。「腰曲がり運動」によって健康関連QOLと腰痛の早期的改善が得られることが示された。

  • Risk Factors for Early 3-Month Postoperative Mortality in Metastatic Spinal Tumor Surgery: A JASA Multicenter Prospective Study.

    Takaaki Uto, Satoshi Kato, Noriaki Yokogawa, Takaki Shimizu, Satoru Demura, Yuki Shiratani, Akinobu Suzuki, Koji Tamai, Kenichiro Kakutani, Yutaro Kanda, Hiroyuki Tominaga, Ichiro Kawamura, Masayuki Ishihara, Masaaki Paku, Toru Funayama, Kousei Miura, Eiki Shirasawa, Hirokazu Inoue, Atsushi Kimura, Takuya Iimura, Hiroshi Moridaira, Koji Akeda, Norihiko Takegami, Kazuo Nakanishi, Hirokatsu Sawada, Koji Matsumoto, Masahiro Funaba, Hidenori Suzuki, Hideaki Nakajima, Tsutomu Oshigiri, Takashi Hirai, Bungo Otsuki, Kazu Kobayakawa, Haruki Funao, Koji Uotani, Shinji Tanishima, Koichi Sairyo, Ko Hashimoto, Chizuo Iwai, Shoji Seki, Masashi Miyazaki, Kazuyuki Watanabe, Toshio Nakamae, Takashi Kaito, Hiroaki Nakashima, Narihito Nagoshi, Shiro Imagama, Kota Watanabe, Gen Inoue, Takeo Furuya

    Spine   51 ( 1 )   52 - 59   2025.04（ ISSN:03622436 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    STUDY DESIGN: Prospective multicenter study. OBJECTIVE: To investigate risk factors for 3-month postoperative mortality in metastatic spinal tumor surgery, focusing on nutritional biomarkers and prognostic scores alongside clinical indicators. SUMMARY OF BACKGROUND DATA: Metastatic spinal tumors affect patient morbidity and mortality. Although prognostic tools exist, they have limitations, particularly in emergency situations requiring rapid assessment. Nutritional biomarkers and prognostic scores may influence outcomes, but their role in predicting early postoperative mortality after spinal tumor surgery, particularly in prospective, multicenter studies, warrants investigation. METHODS: Data from 336 patients undergoing palliative surgery for metastatic spinal tumors were collected from 35 centers. The primary outcome was 3-month postoperative mortality. Univariate and multivariate logistic regression analyses with bootstrapping were performed to identify predictors of early mortality, including demographics, prognostic scores (revised Tokuhashi, Tomita, modified Glasgow Prognostic Score [mGPS], and the New England Spinal Metastasis Score [NESMS]), and nutritional biomarkers. The discriminative ability of these factors was evaluated using the receiver operating characteristic curve analysis. RESULTS: Results: The 3-month postoperative mortality rate was 15.5%, with primary cancer progression accounting for 54% of the deaths. Multivariate analysis revealed that high mGPS (OR=1.989, P=0.008) and low preoperative performance status (PS) (OR=1.412, P=0.034) were significant independent predictors of early mortality, the Tomita score showed a trend towards significance (OR=1.234, P=0.050). The mGPS demonstrated a high discriminative ability, with an area under the curve of 0.716. CONCLUSION: High mGPS and low preoperative PS are significant predictors of 3-month postoperative mortality in patients undergoing surgery for metastatic spinal tumors. Incorporating the mGPS, which reflects nutritional and inflammatory status, into preoperative risk stratification is crucial for optimizing surgical decision-making. LEVEL OF EVIDENCE: 2.

    DOI： 10.1097/BRS.0000000000005359

    PubMed

  • 【人工知能(AI)革命-脊椎脊髄診療の将来像は?】AIを活用した骨粗鬆症性椎体骨折の予後予測

    藪 晋人, 高橋 真治, 玉井 孝司, 星野 雅俊, 寺井 秀富

    脊椎脊髄ジャーナル   38 ( 4 )   209 - 215   2025.04（ ISSN:0914-4412 ）

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    ＜文献概要＞はじめに　本邦において,骨粗鬆症性椎体骨折(osteoporotic vertebral fracture:OVF)は高齢化に伴いますます注目されている疾患であり,その発症は高齢者の日常生活活動や生活の質を著しく低下させる要因となる.多くのOVFは安静や装具といった保存的治療により骨癒合が得られるが,一部の症例では骨癒合不全や高度椎体変形をきたし,慢性腰痛や遅発性神経障害を引き起こすことがある.これらの問題は,患者にとっての負担だけでなく,医療費の増加や介護リスクの増大といった社会的コストをも伴うため,受傷早期の予後予測と適切な治療介入が重要となる.これまでに受傷時の単純X線やMRIを用いたOVFの予後予測が行われているが,さらなる精度の改善が求められる.近年,人工知能(artificial intelligence:AI)の急速な発展により,医療分野においてもAIの導入が加速している.AIは物体認識やパターン認識に優れ,画像やデータベースに登録された大量の臨床データを使用したAIによる疾病の診断や予後予測に関する研究が進められている.本稿では,われわれがAI技術の1つである機械学習モデルを活用して構築したOVFにおける骨癒合不全や椎体変形の予測モデルについて,その概要を述べるとともに,OVFの予後予測について文献的考察を行った.

  • 特集 人工知能(AI)革命-脊椎脊髄診療の将来像は? AIを活用した骨粗鬆症性椎体骨折の予後予測

    藪 晋人, 高橋 真治, 玉井 孝司, 星野 雅俊, 寺井 秀富

    脊椎脊髄ジャーナル   38 ( 4 )   209 - 215   2025.03（ ISSN:09144412 ）

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  • Prognosis of Cervical Diffuse Idiopathic Skeletal Hyperostosis-Related Spine Injuries in Elderly Patients: Analyses of Both Fracture and Spinal Cord Injury Without Fracture

    Segi N.

    Global Spine Journal   15 ( 2 )   321 - 331   2025.03（ ISSN:21925682 ）

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  • The Efficacy of Systemic Transdermal Diclofenac Patch for Postoperative Pain after Lumbar Spinal Surgery

    Uematsu M.

    Spine   50 ( 3 )   201 - 206   2025.02（ ISSN:03622436 ）

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  • Analysis of Risk Factors for Postoperative Progressive Segment Degeneration at the Decompression and Non-decompression Segments after Minimally Invasive Lumbar Decompression Surgery: A 5-year Follow-up Study

    Habibi Hasibullah, Toyoda Hiromitsu, Terai Hidetomi, Yamada Kentaro, Kato Minori, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Iwamae Masayoshi, Sawada Yuta, Kobayashi Yuto, Okamura Yuki, Nakamura Hiroaki

    Spine Surgery and Related Research   9 ( 1 )   22 - 29   2025.01（ eISSN:2432261X ）

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    <p>Introduction: The risk factors for the development of progressive segment degeneration (PSD) after decompression surgery are still unknown. In this study, the risk factors for PSD in patients who undergo decompression surgery for lumbar spinal stenosis with and without coexisting spondylolisthesis and scoliosis were examined, focusing on decompression and non-decompression segments.</p><p>Methods: We reviewed the data of patients with >5 years of postoperative follow up. Radiographic PSD was defined as either the development of an anterolisthesis or retrolisthesis of >3 mm or a decrease in disc height of >3 mm during the 5-year follow up. On the basis of intervertebral segments, the association between PSD and other preoperative clinical findings was analyzed.</p><p>Results: Overall, 840 lumbar segments (L1-L2 to L5-S1) in 168 patients, with a mean age of 69.5±9.2 years, met the inclusion criteria. PSD was observed in 162 (19.3%) lumbar segments. A logistic regression model identified that Cobb angle ≥10° (OR 2.53, 95% CI 1.50-4.24), spondylolisthesis ≥3 mm (OR 4.447, 95% CI 2.06-9.58), and level of segments were more likely to have PSD at the non-decompression level; additionally, lateral listhesis ≥3 mm (OR 2.91, 95% CI 1.08-7.81) was more likely to have PSD in the decompression segments. In clinical outcomes in patients with PSD at baseline and the 5-year follow-up, no significant difference was found.</p><p>Conclusions: Even though PSD does not correlate with worsening symptoms, our study confirms that a higher degree of pre-existing disc degeneration is indicative of a higher PSD in 5 years.</p>

    DOI： 10.22603/ssrr.2024-0014

    PubMed

    CiNii Research

  • Diagnosis and Treatment of Symptomatic Multiple Sacral Perineural Cysts-Technical Note

    Tsujino Masashi, Suzuki Akinobu, Terai Hidetomi, Kato Minori, Toyoda Hiromitsu, Takahashi Shinji, Tamai Koji, Nakamura Hiroaki

    Spine Surgery and Related Research   9 ( 1 )   93 - 99   2025.01（ eISSN:2432261X ）

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    <p>Introduction: Sacral perineural cysts are rarely symptomatic; however, they may occasionally cause various symptoms. As the patient exhibits multiple cysts, it often becomes difficult to determine if these cysts are symptomatic.</p><p>Technical Note: Six patients with multiple sacral cysts, identified using magnetic resonance imaging (MRI), were further examined using myelography and computed tomography (CT) immediately and 6-18 h after myelography. Symptomatic cysts were exclusively diagnosed as not enhanced immediately (filling defect sign) but displayed enhancement later (delayed filling sign/retention sign) compared to the subarachnoid space. A minimal laminectomy was performed on the target cyst. The dura and epineurium with the arachnoid of the cyst were then longitudinally incised along the nerve root, and the adhesion at the junction between the cyst and the dura mater was released. The incised epineurium and dura mater were sutured using 6-0 nylon and covered with multiple layers of polyglycolic acid seat and fibrin glue. A suction drain was placed for 1 or 2 days, and the patients were mobilized on postoperative day 1. Symptoms improved in all patients; however, the improvement ratio varied. At an average follow-up of 39 months, no recurrence was observed on the MRI.</p><p>Conclusions: This case series reports the diagnostic and surgical methods for multiple sacral perineural cysts and their outcomes. Delayed CT myelography is helpful in diagnosing symptomatic cysts. Moreover, all cysts with filling defect signs or delayed filling/retention signs demonstrated neural adhesions in the neck. Microsurgical fenestration and the release of adhesions are effective for the improvement of symptoms without recurrence.</p>

    DOI： 10.22603/ssrr.2024-0021

    PubMed

    CiNii Research

  • Open-Door Cervical Laminoplasty Using Instrumentation of Every Level Versus Alternate Levels

    Tamai K.

    Journal of Bone and Joint Surgery   107 ( 2 )   144 - 151   2025.01（ ISSN:00219355 ）

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  • SPINE20 Recommendations 2024 -Spinal Disability: Social Inclusion as a Key to Prevention and Management

    Menezes C.M.

    Global Spine Journal   15 ( 1 )   8 - 20   2025.01（ ISSN:21925682 ）

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  • 最小侵襲腰椎除圧術後の除圧セグメントと非除圧セグメントにおける進行性区域変性症のリスク因子解析　5年間の経過観察研究(Analysis of Risk Factors for Postoperative Progressive Segment Degeneration at the Decompression and Non-decompression Segments after Minimally Invasive Lumbar Decompression Surgery: A 5-year Follow-up Study)

    Habibi Hasibullah, Toyoda Hiromitsu, Terai Hidetomi, Yamada Kentaro, Kato Minori, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Iwamae Masayoshi, Sawada Yuta, Kobayashi Yuto, Okamura Yuki, Nakamura Hiroaki

    Spine Surgery and Related Research   9 ( 1 )   22 - 29   2025.01

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    除圧手術を受けた腰部脊柱管狭窄症/脊椎すべり症・側彎症患者における術後進行性区域変性症(PSD)発症のリスク因子について、特に除圧セグメントと非除圧セグメントに焦点をあてて検討した。腰部脊柱管狭窄症患者168例の840セグメント(L1-L2、L5-S1)を対象に5年以上の経過観察を行い、X線学的に3mm超の前方すべり、後方すべりまたは椎間板高の3mm超の減少が生じていればPSDと判定を下した。PSDの発症を162セグメント(19.3%)に認め、発症率は除圧セグメントが46.9%、非除圧セグメントが23.5%と除圧セグメントの方が有意に高かった。PSD発症の独立リスク因子として、非除圧セグメントではCobb角10°以上、3mm以上の脊椎すべり症、L3/4、L4/5、L5/Sが示され、除圧セグメントでは3mm以上の側方すべりが抽出された。5年間においてPSDの発症を認めたのは168例のうち106例(63.1%)であり、PSD発症群の方が非発症群より脚部痛、脚部のしびれ、腰痛を示すVASスコアは不良であった。既存の椎間板変性によって術後PSDの発症リスクが高まる可能性が示された。

  • Risk factors for adjacent segment disease after lateral lumbar interbody fusion for lumbar spinal canal stenosis with instability

    Sawada Y.

    European Spine Journal   2025（ ISSN:09406719 ）

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  • Predicting Postoperative Neurological Outcomes in Metastatic Spinal Tumor Surgery Using Machine Learning

    Maki S.

    Spine   51 ( 2 )   100 - 106   2025（ ISSN:03622436 ）

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  • Disc Level–Specific outcomes of intradiscal condoliase injection for lumbar disc herniation: A multicenter retrospective study

    Watanabe K.

    Journal of Orthopaedic Science   2025（ ISSN:09492658 ）

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  • Cement leakage risk reduction and propensity score matching analysis of clinical efficacy for Cement-Augmented fenestrated pedicle screw in patients with osteoporosis

    Uematsu M.

    European Spine Journal   2025（ ISSN:09406719 ）

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  • Does cessation of combustible cigarette and heated tobacco product smoking immediately following a fracture benefit fracture healing? In vivo and in vitro validation

    Iwamae M.

    Biochemical and Biophysical Research Communications   736   150512   2024.12（ ISSN:0006291X ）

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  • Is orthotic treatment beneficial for fresh osteoporotic vertebral fractures? A propensity score matching study

    Iwamae M.

    Spine Journal   24 ( 12 )   2343 - 2355   2024.12（ ISSN:15299430 ）

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  • Impact of malnutrition on mortality and neurological recovery of older patients with spinal cord injury

    Tamai K.

    Scientific Reports   14 ( 1 )   5853   2024.12

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  • Is Intraoperative Blood Loss Volume in Elderly Cervical Spine Injury Surgery Greater in Patients with Ankylosis? A Multicenter Survey

    Uehara Masashi, Ikegami Shota, Takizawa Takashi, Oba Hiroki, Yokogawa Noriaki, Sasagawa Takeshi, Nakashima Hiroaki, Segi Naoki, Ito Sadayuki, Funayama Toru, Eto Fumihiko, Yamaji Akihiro, Watanabe Kota, Nori Satoshi, Takeda Kazuki, Furuya Takeo, Yunde Atsushi, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Terashima Yoshinori, Hirota Ryosuke, Suzuki Hidenori, Imajo Yasuaki, Tonomura Hitoshi, Sakata Munehiro, Hashimoto Ko, Onoda Yoshito, Kawaguchi Kenichi, Haruta Yohei, Suzuki Nobuyuki, Kato Kenji, Uei Hiroshi, Sawada Hirokatsu, Nakanishi Kazuo, Misaki Kosuke, Terai Hidetomi, Tamai Koji, Kuroda Akiyoshi, Inoue Gen, Kakutani Kenichiro, Kakiuchi Yuji, Kiyasu Katsuhito, Tominaga Hiroyuki, Tokumoto Hiroto, Iizuka Yoichi, Takasawa Eiji, Akeda Koji, Takegami Norihiko, Funao Haruki, Oshima Yasushi, Kaito Takashi, Sakai Daisuke, Yoshii Toshitaka, Ohba Tetsuro, Otsuki Bungo, Seki Shoji, Miyazaki Masashi, Ishihara Masayuki, Okada Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   8 ( 6 )   575 - 582   2024.11（ eISSN:2432261X ）

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    <p>Introduction: Preoperative estimations of blood loss are important when planning surgery for cervical spine injuries in older adults. The association between ankylosis and blood loss in perioperative management is of particular interest. This multicenter database review aimed to evaluate the impact of ankylosis on surgical blood loss volume in elderly patients with cervical spine injury.</p><p>Methods: The case histories of 1512 patients with cervical spine injury at among 33 institutions were reviewed. After the exclusion of patients without surgery or whose blood loss or ankylosis status was unclear, 793 participants were available for analysis. Differences in blood loss volume were compared between the Ankylosis (+) group with ankylosis at the cervical level and the Ankylosis (−) group without by the inverse probability of treatment weighting (IPTW) method using a propensity score.</p><p>Results: Of the 779 patients (mean age: 75.0±6.3 years) eligible for IPTW calculation, 257 (32.4%) had ankylosis at the cervical level. The mean blood loss volume was higher in Ankylosis (+) patients than in Ankylosis (−) patients (P<0.001). This difference did not reach statistical significance when weighted by background factors, with mean blood loss of 244 mL and 188 mL, respectively, after adjustment.</p><p>Conclusions: This study revealed that ankylosis was significantly associated with increased blood loss volume when unadjusted by surgical time. Elderly patients with cervical spine injury accompanied by ankylosis appear predisposed to higher bleeding and severe hemorrhage, both as a result of the condition and their particular demographic characteristics.</p>

    DOI： 10.22603/ssrr.2023-0118

    PubMed

    CiNii Research

  • Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries

    Battaglini D.

    Heart and Lung   68   131 - 144   2024.11（ ISSN:01479563 ）

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  • 脊椎強直を呈する高齢患者における頸椎損傷手術によって出血量は増大するのか　多施設共同調査(Is Intraoperative Blood Loss Volume in Elderly Cervical Spine Injury Surgery Greater in Patients with Ankylosis?: A Multicenter Survey)

    Uehara Masashi, Ikegami Shota, Takizawa Takashi, Oba Hiroki, Yokogawa Noriaki, Sasagawa Takeshi, Nakashima Hiroaki, Segi Naoki, Ito Sadayuki, Funayama Toru, Eto Fumihiko, Yamaji Akihiro, Watanabe Kota, Nori Satoshi, Takeda Kazuki, Furuya Takeo, Yunde Atsushi, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Terashima Yoshinori, Hirota Ryosuke, Suzuki Hidenori, Imajo Yasuaki, Tonomura Hitoshi, Sakata Munehiro, Hashimoto Ko, Onoda Yoshito, Kawaguchi Kenichi, Haruta Yohei, Suzuki Nobuyuki, Kato Kenji, Uei Hiroshi, Sawada Hirokatsu, Nakanishi Kazuo, Misaki Kosuke, Terai Hidetomi, Tamai Koji, Kuroda Akiyoshi, Inoue Gen, Kakutani Kenichiro, Kakiuchi Yuji, Kiyasu Katsuhito, Tominaga Hiroyuki, Tokumoto Hiroto, Iizuka Yoichi, Takasawa Eiji, Akeda Koji, Takegami Norihiko, Funao Haruki, Oshima Yasushi, Kaito Takashi, Sakai Daisuke, Yoshii Toshitaka, Ohba Tetsuro, Otsuki Bungo, Seki Shoji, Miyazaki Masashi, Ishihara Masayuki, Okada Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   8 ( 6 )   575 - 582   2024.11

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    高齢頸椎損傷患者において脊椎強直が術中出血量に影響を及ぼすかどうか検討した。頸椎損傷に対して手術を施行された高齢患者779例を対象に多施設共同調査を行い、逆確率重み付け(IPTW)法を用いて脊椎強直群257例(男性208例、女性49例、平均75.2±6.3歳)と非強直群522例(男性326例、女性196例、平均74.9±6.3歳)の術中出血量を比較した。平均手術時間は脊椎強直群が177分、非強直群が159分、平均出血量は強直群が279mL、非強直群が171mLであり、出血量は強直群の方が有意に多かったが、背景因子の重み付けを行うと強直群244mL、非強直群188mLとなり有意差はみられなかった。手術時間は強直群の方が非強直群より長く、この結果に基づいてIPTW法を実施した。その結果、平均出血量は強直群が333mL、非強直群が170mLと強直群の方が有意に高値を示していた。1000mL以上の出血がみられた患者も強直群に有意に多かった。頸椎損傷に対して手術を施行された高齢患者では、脊椎強直が術中出血量高値と有意に関連することが明らかになった。

  • Low Nutrition before Injury Is a Risk Factor for Dysphagia in Older Patients with Cervical Spinal Cord Injury: Based on a Multicenter Data of 707 Patients

    Segi Naoki, Nakashima Hiroaki, Ito Sadayuki, Ouchida Jun, Yokogawa Noriaki, Sasagawa Takeshi, Funayama Toru, Eto Fumihiko, Watanabe Kota, Nori Satoshi, Furuya Takeo, Yunde Atsushi, Terashima Yoshinori, Hirota Ryosuke, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Kawaguchi Kenichi, Haruta Yohei, Hashimoto Ko, Onoda Yoshito, Nakanishi Kazuo, Misaki Kosuke, Ikegami Shota, Uehara Masashi, Suzuki Hidenori, Imajo Yasuaki, Uei Hiroshi, Sawada Hirokatsu, Terai Hidetomi, Tamai Koji, Kuroda Akiyoshi, Inoue Gen, Suzuki Nobuyuki, Kato Kenji, Akeda Koji, Takegami Norihiko, Iizuka Yoichi, Oshima Yasushi, Tonomura Hitoshi, Kiyasu Katsuhito, Funao Haruki, Yoshii Toshitaka, Ishihara Masayuki, Kaito Takashi, Seki Shoji, Kakutani Kenichiro, Tominaga Hiroyuki, Ohba Tetsuro, Sakai Daisuke, Otsuki Bungo, Miyazaki Masashi, Okada Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   8 ( 5 )   473 - 479   2024.09（ eISSN:2432261X ）

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    <p>Introduction: For older adults, dysphagia is a serious problem that can occur after spinal cord injury (SCI), but its risk factors are unclear. This study aimed to identify risk factors for dysphagia in elderly patients (≥65 years) with cervical SCI.</p><p>Methods: This multicenter study included 707 patients with cervical SCI (mean age 75.3 years). Univariate and multivariate analyses were conducted for patient characteristics and geriatric nutritional risk index (GNRI).</p><p>Results: Dysphagia occurred in 69 patients (9.8%). The significant factors were as follows: male sex (odds ratio [OR] 3.43), GNRI <92 (1.83), dementia (2.94), fracture (3.40), complete paralysis (3.61), anterior surgery (3.74), and tracheostomy (17.06). Age was not identified as a risk factor.</p><p>Conclusions: Low GNRI before injury was one of the independent risk factors for dysphagia after geriatric cervical SCI. GNRI represents the comprehensive nutritional status of the elderly and reflects feeding function and its recovery capacity.</p>

    DOI： 10.22603/ssrr.2023-0227

    PubMed

    CiNii Research

  • Minimum Clinically Important Difference of the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire for Patients with Lumbar Spine Disease Undergoing Posterior Surgery by Generation

    Kato Minori, Terai Hidetomi, Namikawa Takashi, Matsumura Akira, Hoshino Masatoshi, Toyoda Hiromitsu, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Sawada Yuta, Iwamae Masayoshi, Okamura Yuki, Kobayashi Yuto, Nakamura Hiroaki

    Spine Surgery and Related Research   8 ( 5 )   518 - 527   2024.09（ eISSN:2432261X ）

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    <p>Introduction: Few studies have assessed the minimum clinically important difference (MCID) of each Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ) domain. This study assessed MCIDs of JOABPEQ in patients with lumbar spine disease by generation.</p><p>Methods: We evaluated the JOABPEQ score of 805 consecutive patients with lumbar spine disease undergoing posterior surgery preoperatively and 1 year postoperatively. MCIDs of each JOABPEQ domain were determined using anchor- and distribution-based methods according to age. A question based on the concept of a health transition item was used as the anchor for the MCID decision.</p><p>Results: Overall, MCIDs of the JOABPEQ were 28.6 and 27.3 points for pain-related disorder and gait disturbance, respectively. The MCID for the lumbar spine dysfunction domain did not reach 0.6 over the area under the curve. Regarding the differences among generations, MCIDs of pain-related disorder and gait disturbance domains differed slightly between the elderly and middle-aged. The psychological disorder domain did not reflect clinically meaningful changes in the elderly. MCIDs of the social life disturbance domain decreased with age.</p><p>Conclusions: Focusing on achieving the ideal responsiveness of patient-reported outcomes across generations, MCIDs of the pain-related disorder and gait disturbance domains may be valuable for patients, regardless of age, when adopting the JOABPEQ for patients with lumbar spine disease undergoing surgery. This study only evaluated cases that underwent posterior lumbar surgery. Future research will necessitate conducting surveys concerning the outcomes of various treatments for lumbar spine disease.</p>

    DOI： 10.22603/ssrr.2023-0293

    PubMed

    CiNii Research

  • 腰椎疾患患者の年代別にみた日本整形外科学会背部痛評価質問票の最小臨床重要変化量(Minimum Clinically Important Difference of the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire for Patients with Lumbar Spine Disease Undergoing Posterior Surgery by Generation)

    Kato Minori, Terai Hidetomi, Namikawa Takashi, Matsumura Akira, Hoshino Masatoshi, Toyoda Hiromitsu, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Sawada Yuta, Iwamae Masayoshi, Okamura Yuki, Kobayashi Yuto, Nakamura Hiroaki

    Spine Surgery and Related Research   8 ( 5 )   518 - 527   2024.09

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    腰椎疾患患者における日本整形外科学会背部痛評価質問票(JOABPEQ)の最小臨床重要変化量(MCID)を年代別に検討した。後方アプローチにて手術を施行された腰椎疾患患者805例を対象に、術前と術後1年にJOABPEQを測定し、アンカーベース法と分布ベース法を用いて各JOABPEQドメインのMCIDを算出した。被験者は65歳未満の中年群226例(男性112例、女性114例、平均55.8±8.8歳)、65～74歳の前期高齢者群316例(男性151例、女性165例、平均70.1±2.9歳)、75歳以上の後期高齢者群263例(男性108例、女性155例、平均79.5±2.8歳)に分類した。ASA IIIは後期高齢者群に有意に多くみられ、JOAスコアは術前の12.5点から術後1年目に22.5点に増加し、改善率は60.7%、腰痛VASスコアの減少度は24.0mm、脚部痛VASスコアの減少度は40.3mmを示していた。JOABPEQの各ドメイン(疼痛関連障害、歩行障害、社会生活障害)は術後に20点超を示し、年代別の比較では後期高齢者群のスコアは中年群より有意に低かった。アンカーベース法の結果をみると、改善と判定された患者数は中年群が156例、前期高齢者群が186例、後期高齢者群が124例であり、年齢を重ねるのに伴って改善率は低くなっていた。疼痛関連障害と歩行障害のMCIDにみられる中年群と高齢者群との差は軽微なものであり、心理的障害ドメインに群間差はなく、社会生活障害のMCIDは加齢に伴って減少していた。

  • 頸髄損傷高齢患者の嚥下障害のリスク因子としての損傷前低栄養　707例の多施設データ(Low Nutrition before Injury Is a Risk Factor for Dysphagia in Older Patients with Cervical Spinal Cord Injury: Based on a Multicenter Data of 707 Patients)

    Segi Naoki, Nakashima Hiroaki, Ito Sadayuki, Ouchida Jun, Yokogawa Noriaki, Sasagawa Takeshi, Funayama Toru, Eto Fumihiko, Watanabe Kota, Nori Satoshi, Furuya Takeo, Yunde Atsushi, Terashima Yoshinori, Hirota Ryosuke, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Kawaguchi Kenichi, Haruta Yohei, Hashimoto Ko, Onoda Yoshito, Nakanishi Kazuo, Misaki Kosuke, Ikegami Shota, Uehara Masashi, Suzuki Hidenori, Imajo Yasuaki, Uei Hiroshi, Sawada Hirokatsu, Terai Hidetomi, Tamai Koji, Kuroda Akiyoshi, Inoue Gen, Suzuki Nobuyuki, Kato Kenji, Akeda Koji, Takegami Norihiko, Iizuka Yoichi, Oshima Yasushi, Tonomura Hitoshi, Kiyasu Katsuhito, Funao Haruki, Yoshii Toshitaka, Ishihara Masayuki, Kaito Takashi, Seki Shoji, Kakutani Kenichiro, Tominaga Hiroyuki, Ohba Tetsuro, Sakai Daisuke, Otsuki Bungo, Miyazaki Masashi, Okada Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   8 ( 5 )   473 - 479   2024.09

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    頸髄損傷を呈した高齢患者における嚥下障害発症のリスク因子について検討した。65歳以上の頸髄損傷患者707例(男性511例、女性196例、平均75.3±6.7歳)を対象に多施設研究を行った。高齢者栄養評価指標(GNRI)は平均96.9、5項目修正フレイル指標(mFI-5)が2点以下を示していたのが約80%、頸部骨折を38%に認め、米国脊椎損傷学会障害度指数(AIS)Dを伴う麻痺が35%に検出された。被験者のうち66%に手術を施行し、後方アプローチが大半を占めていた。嚥下障害の発症を69例(9.8%)に認め、単変量解析では男性、GNRI 92未満、喫煙、後縦靱帯骨化、骨折、完全麻痺(AIS AまたはB)、手術治療、前方アプローチ、および気管切開が嚥下障害の発症に関わる有意なリスク因子として示された。ロジスティック回帰分析では男性、GNRI 92未満、認知症、骨折、完全麻痺、前方アプローチおよび気管切開が嚥下障害の有意なリスク因子として抽出された。頸髄受傷前のGNRI低値が嚥下障害発症のリスク因子のひとつであることが明らかになった。

  • Effects of Orthotic Treatment on Fresh Osteoporotic Vertebral Fractures

    Iwamae Masayoshi, Takahashi Shinji, Terai Hidetomi, Tamai Koji, Hoshino Masatoshi, Toyoda Hiromitsu, Suzuki Akinobu, Kato Minori, Umano Masayuki, Kobayashi Yuto, Sasaki Ryo, Uematsu Masato, Shimada Nagakazu, Nakamura Hiroaki

    Journal of Spine Research   15 ( 6 )   869 - 876   2024.06（ ISSN:18847137 ） （ eISSN:24351563 ）

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    <p>Osteoporotic vertebral fractures (OVF) are the most common osteoporotic fractures, affecting patients' quality of life and activity of daily life. Although orthotics is generally the treatment of choice for conservative treatment of OVF, the current evidence for orthotics is limited. Prospective studies without orthotics for the conservative treatment of OVF are difficult due to an ethical point of view because it is common sense that orthotics are the treatment of choice. In fact, there are very few reports that have verified the effectiveness of orthotics compared to no orthotics in the past. Therefore, we compared data from a cohort without orthotics and a cohort with orthotics using propensity score matching to demonstrate the effect of orthotics. In this review, we summarize the effects of orthotics in OVF based on reports of orthotics, including our previous study.</p>

    DOI： 10.34371/jspineres.2024-0610

    CiNii Research

  • Epidemiology of Cervical Fracture/Cervical Spinal Cord Injury and Changes in Surgical Treatment Modalities in Elderly Individuals During a 10-year Period: A Nationwide Multicenter Study in Japan

    Segi N.

    Global Spine Journal   14 ( 5 )   1583 - 1594   2024.06（ ISSN:21925682 ）

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  • Risk Factors for Residual Back Pain After Balloon Kyphoplasty for Osteoporotic Vertebral Fracture

    Salimi H.

    Indian Journal of Orthopaedics   58 ( 5 )   567 - 574   2024.05（ ISSN:00195413 ）

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  • Neurological recovery rate and predictive factors of incomplete AIS grade C spinal cord injury in the older aged population

    Tamai K.

    Spinal Cord   62 ( 4 )   149 - 155   2024.04（ ISSN:13624393 ）

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  • Residual Paresthesia After Surgery for Degenerative Cervical Myelopathy: Incidence and Impact on Clinical Outcomes and Satisfaction

    Tamai K.

    Spine   49 ( 6 )   378 - 384   2024.03（ ISSN:03622436 ）

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  • Influence of the timing of surgery for cervical spinal cord injury without bone injury in the elderly: A retrospective multicenter study

    Nori S.

    Journal of Orthopaedic Science   29 ( 2 )   480 - 485   2024.03（ ISSN:09492658 ）

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  • 高齢者の骨損傷を伴わない頸髄損傷に対して手術のタイミングが及ぼす影響　後ろ向き多施設共同研究(Influence of the timing of surgery for cervical spinal cord injury without bone injury in the elderly: A retrospective multicenter study)

    Nori Satoshi, Watanabe Kota, Takeda Kazuki, Yamane Junichi, Kono Hitoshi, Yokogawa Noriaki, Sasagawa Takeshi, Ando Kei, Nakashima Hiroaki, Segi Naoki, Funayama Toru, Eto Fumihiko, Yamaji Akihiro, Furuya Takeo, Yunde Atsushi, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Terashima Yoshinori, Hirota Ryosuke, Suzuki Hidenori, Imajo Yasuaki, Ikegami Shota, Uehara Masashi, Tonomura Hitoshi, Sakata Munehiro, Hashimoto Ko, Onoda Yoshito, Kawaguchi Kenichi, Haruta Yohei, Uei Hiroshi, Sawada Hirokatsu, Nakanishi Kazuo, Misaki Kosuke, Terai Hidetomi, Tamai Koji, Shirasawa Eiki, Inoue Gen, Kiyasu Katsuhito, Iizuka Yoichi, Takasawa Eiji, Funao Haruki, Kaito Takashi, Yoshii Toshitaka, Ishihara Masayuki, Okada Seiji, Imagama Shiro, Kato Satoshi

    Journal of Orthopaedic Science   29 ( 2 )   480 - 485   2024.03（ ISSN:0949-2658 ）

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    高齢者の骨損傷を伴わない頸髄損傷(CSCI)に対する受傷48時間以内の手術施行が神経学的回復に及ぼす影響を検討した。2010～2020年に手術を受けた65歳以上のCSCI患者159例を対象に多施設共同後ろ向き研究を行い、受傷48時間以内の早期手術施行群24例(男性62.5%、平均73.5±6.12歳)と48時間以降の後期手術施行群135例(男性73.3%、平均74.1±6.02歳)に分類した。全例のうち97.5%に後方アプローチが採用されており、術式、手術時間、出血量のほか、硬膜断裂、手術部位感染症、C5麻痺、神経学的増悪、心筋梗塞、脳梗塞、せん妄、嚥下障害、呼吸不全、肺塞栓症などの合併症の発症に関して早期手術群と後期手術群との間に有意差はみられなかった。受傷後6ヵ月におけるAmerican Spinal Injury Association Motor Score(AMS)は後期手術群の方が早期手術群より有意に高値を示していたが、ベースライン時から6ヵ月後までのAMSの変化は早期手術群の方が有意に大きかった。線形重回帰分析では、ベースライン時のAMS、せん妄、肺炎、糖尿病が術後のAMSの変化に有意な負の影響を及ぼすことが判明し、早期手術施行とAMSの変化との間に有意な関連は認められなかった。

  • Degeneration of Cervical Multifidus Muscles Negatively Affects Physical Activity-related Quality of Life After Laminoplasty for Degenerative Cervical Myelopathy.

    Masayoshi Iwamae, Koji Tamai, Akinobu Suzuki, Hidetomi Terai, Masatoshi Hoshino, Minori Kato, Hiromitsu Toyoda, Shinji Takahashi, Akito Yabu, Yuta Sawada, Hiroaki Nakamura

    Clinical spine surgery   37 ( 8 )   E364 - E370   2024.02（ ISSN:23800186 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    STUDY DESIGN: A retrospective cohort study. OBJECTIVE: The study aimed to investigate the related factors affecting physical activity-related quality of life (QOL) after 2 years of cervical laminoplasty for degenerative cervical myelopathy (DCM), focusing on the degree of preoperative degeneration of the cervical multifidus muscles. SUMMARY OF BACKGROUND DATA: The association between paraspinal muscle degeneration and clinical outcomes after spinal surgery is being investigated. The effect of preoperative degeneration of the cervical multifidus muscles in patients undergoing cervical laminoplasty is ambiguous. METHODS: Patients who underwent laminoplasty for DCM and followed up for more than 2 years were reviewed. To evaluate physical QOL, the physical component summary (PCS) of the 36-Item Short-Form Health Survey (SF-36) was recorded at 2 years postoperatively. The degree of preoperative degeneration in the multifidus muscles at the C4 and C7 levels on axial T2-weighted magnetic resonance imaging (MRI) was categorized according to the Goutallier grading system. The correlation between 2-year postoperative PCS and each preoperative clinical outcome, radiographic parameter, and MRI finding, including Goutallier classification, was analyzed. Variables with a P value <0.10 in univariate analysis were included in multiple linear regression analysis. RESULTS: In total, 106 consecutive patients were included. The 2-year postoperative PCS demonstrated significant correlation with age (R=-0.358, P=0.002), preoperative JOA score (R=0.286, P=0.021), preoperative PCS (R=0.603, P<0.001), C2-C7 lordotic angle (R=-0.284, P=0.017), stenosis severity (R=-0.271, P=0.019), and Goutallier classification at the C7 level (R=-0.268, P=0.021). In multiple linear regression analysis, sex (β=-0.334, P=0.002), age (β=-0.299, P=0.013), preoperative PCS (β=0.356, P=0.009), and Goutallier classification at the C7 level (β=-0.280, P=0.018) were significantly related to 2-year postoperative PCS. CONCLUSIONS: Increased degeneration of the multifidus muscle at the C7 level negatively affected physical activity-related QOL postoperatively. These results may guide spine surgeons in predicting physical activity-related QOL in patients with DCM after laminoplasty. LEVEL OF EVIDENCE: Level III.

    DOI： 10.1097/BSD.0000000000001585

    PubMed

  • 連載 最新原著レビュー 新型コロナウイルス感染症パンデミックが脊椎疾患を有する高齢者に与えた影響

    寺井 秀富, 高橋 真治, 玉井 孝司, 中村 博亮

    整形外科   75 ( 2 )   165 - 167   2024.02（ ISSN:00305901 ） （ eISSN:24329444 ）

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  • Prognostic Factors for Respiratory Dysfunction for Cervical Spinal Cord Injury and/or Cervical Fractures in Elderly Patients: A Multicenter Survey.

    Hirota R, Terashima Y, Ohnishi H, Yamashita T, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Watanabe K, Yamane J, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    Global spine journal   14 ( 1 )   101 - 112   2024.01（ ISSN:2192-5682 ）

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  • Short-Term Risk Factors for Distal Junctional Kyphosis after Spinal Reconstruction Surgery in Patients with Osteoporotic Vertebrae

    Sawada Y.

    Asian Spine Journal   18 ( 1 )   101 - 109   2024（ ISSN:19761902 ）

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  • Machine-learning-based approach for nonunion prediction following osteoporotic vertebral fractures.

    Takahashi S, Terai H, Hoshino M, Tsujio T, Kato M, Toyoda H, Suzuki A, Tamai K, Yabu A, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   32 ( 11 )   3788 - 3796   2023.11（ ISSN:0940-6719 ）

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  • The Impact of Multidisciplinary Approaches to Social Functioning on Surgical Outcomes After Surgery for Cervical Myelopathy.

    Tamai K, Terai H, Watanabe S, Tashiro Y, Omine T, Katsuda H, Shimada N, Kobayashi Y, Nakamura H

    Spine   48 ( 19 )   1365 - 1372   2023.10（ ISSN:0362-2436 ）

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  • Prognostic impact of respiratory dysfunction in elderly patients with cervical spinal cord injury and/or fractures: a multicenter survey.

    Hirota R, Terashima Y, Ohnishi H, Yamashita T, Yokogawa N, Sasagawa T, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   32 ( 10 )   3522 - 3532   2023.10（ ISSN:0940-6719 ）

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  • Risk of Revision After Vertebral Augmentation for Osteoporotic Vertebral Fracture: A Narrative Review.

    Takahashi S, Inose H, Tamai K, Iwamae M, Terai H, Nakamura H

    Neurospine   20 ( 3 )   852 - 862   2023.09（ ISSN:2586-6583 ）

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  • Development of locomotive syndrome in elderly population after COVID-19 outbreak: A population-based cross-sectional study with over 12,000 participants.

    Terai H, Tamai K, Takahashi S, Katsuda H, Shimada N, Hori Y, Kobayashi Y, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   28 ( 4 )   895 - 900   2023.07（ ISSN:0949-2658 ）

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  • Factors Predicting the Final Diagnosis in Image-Guided Percutaneous Needle Biopsy for Suspected Spinal Tumors.

    Oka M, Suzuki A, Terai H, Kato M, Toyoda H, Takahashi S, Tamai K, Nakamura H

    Journal of clinical medicine   12 ( 13 )   2023.06（ ISSN:2077-0383 ）

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  • Risk of Residual Low Back Pain in Conservative Treatment of Osteoporotic Vertebral Fractures without Poor Prognostic Factors on Magnetic Resonance Imaging

    Iwamae Masayoshi, Terai Hidetomi, Tamai Koji, Hoshino Masatoshi, Takahashi Shinji, Umano Masayuki, Kobayashi Yuto, Katsuda Hiroshi, Kaneda Kunikazu, Shimada Nagakazu, Nakamura Hiroaki

    Journal of Spine Research   14 ( 5 )   786 - 793   2023.05（ ISSN:18847137 ） （ eISSN:24351563 ）

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    <p><b>Introduction: </b>Poor prognostic factors (PPF) on magnetic resonance imaging (MRI) (confined high intensity area or diffuse low intensity area in fractured vertebrae on T2-weighted MR images) predict delayed union after osteoporotic vertebral fractures (OVF). However, although we have treated OVF without PPF on MRI conservatively, there have been a few cases with residual low back pain. Therefore, the objectives of this study were to identify the risk factors of residual low back pain despite the absence of PPF on MRI, and to investigate clinical and radiographical characteristics during follow-up in such patients.</p><p><b>Methods: </b>This retrospective cohort study included 55 patients (mean age 75.1 years, 47 females) who were followed up for over 6 months after conservative treatment for OVF. The cases with PPF on MRI or with cauda equina or nerve root compressed on MRI were excluded. The participants were divided into two groups: the residual low back pain group (VAS in low back pain ≥40 at 6 months; 16 patients) and the control group (39 patients). Evaluation items included radiographic parameters on dynamic films (sitting/supine lateral views) and whole spine X-ray, VAS in low back pain/buttock pain at the initial examination and 6 months after injury.</p><p><b>Results: </b>Firstly, to identify the risk factors, univariate analysis showed significant differences in VAS in buttock pain at initial examination (p = 0.002), motion angle of fractured vertebrae (p = 0.047), TK (p = 0.046), and LL (p = 0.031). Multivariate analysis showed that VAS in buttock pain at first examination was an independent risk factor for residual low back pain 6 months after injury (adjusted odds ratio = 1.526, p = 0.019). Secondly, the patients in the residual low back pain group were significantly larger SVA at 6 months and more change in the height of anterior wall of fractured vertebrae in dynamic films at 6 months than those in the control group (p = 0.029 and p = 0.011, respectively). Moreover, the cases with confined high intensity area on T2-weighted images at 6 months were significantly more in the residual low back pain group than in the control group (p = 0.006). </p><p><b>Conclusions: </b>The risk factor for residual low back pain after conservative treatment for OVF without PPF on MRI was buttock pain at the initial examination. The causes of residual low back pain were a larger SVA and delayed union of the fractured vertebrae. Patients with buttock pain at the initial examination should be carefully followed up, and surgical intervention such as vertebroplasty might be considered as necessary.</p>

    DOI： 10.34371/jspineres.2022-0050

    CiNii Research

  • Risk Factors for Poor Outcome after Palliative Surgery for Metastatic Spinal Tumors.

    Suzuki A, Terai H, Takahashi S, Kato M, Toyoda H, Tamai K, Hori Y, Okamura Y, Nakamura H

    Journal of clinical medicine   12 ( 10 )   2023.05（ ISSN:2077-0383 ）

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  • A case report of pathological fracture of the thoracic spine with a difficulty in diagnosis

    SUZUKI Maya

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   66 ( 3 )   507 - 508   2023.05（ ISSN:00089443 ） （ eISSN:13490885 ）

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  • Deep Learning Algorithm for Identifying Cervical Cord Compression Due to Degenerative Canal Stenosis on Radiography.

    Tamai K, Terai H, Hoshino M, Tabuchi H, Kato M, Toyoda H, Suzuki A, Takahashi S, Yabu A, Sawada Y, Iwamae M, Oka M, Nakaniwa K, Okada M, Nakamura H

    Spine   48 ( 8 )   519 - 525   2023.04（ ISSN:0362-2436 ）

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  • Neck pain and related factors in patients with rheumatoid arthritis.

    Suzuki A, Yamada K, Yabu A, Tamai K, Takahashi S, Inui K, Okano T, Koike T, Nakamura H

    Modern rheumatology   33 ( 3 )   503 - 508   2023.04（ ISSN:1439-7595 ）

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  • Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture.

    Tamai K, Terai H, Nakamura H, Yokogawa N, Sasagawa T, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Watanabe K, Yamane J, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    Journal of clinical medicine   12 ( 6 )   2023.03（ ISSN:2077-0383 ）

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  • Effects of Dementia on Outcomes after Cervical Spine Injuries in Elderly Patients: Evaluation of 1512 Cases in a Nationwide Multicenter Study in Japan.

    Yamada Y, Yokogawa N, Kato S, Sasagawa T, Tsuchiya H, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Yamane J, Nori S, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Watanabe K

    Journal of clinical medicine   12 ( 5 )   2023.02（ ISSN:2077-0383 ）

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  • Characteristics of the cervical spine and cervical cord injuries in older adults with cervical ossification of the posterior longitudinal ligament.

    Okuwaki S, Funayama T, Koda M, Eto F, Yamaji A, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    Scientific reports   13 ( 1 )   2689   2023.02

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  • Periostin increased by mechanical stress upregulates interleukin-6 expression in the ligamentum flavum.

    Yabu A, Suzuki A, Hayashi K, Hori Y, Terai H, Orita K, Habibi H, Salimi H, Kono H, Toyoda H, Maeno T, Takahashi S, Tamai K, Ozaki T, Iwamae M, Ohyama S, Imai Y, Nakamura H

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology   37 ( 2 )   e22726   2023.02（ ISSN:0892-6638 ）

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  • Risk Factors for Early Mortality in Older Patients with Traumatic Cervical Spine Injuries-A Multicenter Retrospective Study of 1512 Cases.

    Kobayashi M, Yokogawa N, Kato S, Sasagawa T, Tsuchiya H, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Yamane J, Nori S, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Watanabe K

    Journal of clinical medicine   12 ( 2 )   2023.01（ ISSN:2077-0383 ）

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  • SPINE20 recommendations 2023: One Earth, one family, one future WITHOUT spine DISABILITY.

    Chhabra HS, Tamai K, Alsebayel H, AlEissa S, Alqahtani Y, Arand M, Basu S, Blattert TR, Bussières A, Campello M, Costanzo G, Côté P, Darwano B, Franke J, Garg B, Hasan R, Ito M, Kamra K, Kandziora F, Kassim N, Kato S, Lahey D, Mehta K, Menezes CM, Muehlbauer EJ, Mullerpatan R, Pereira P, Roberts L, Ruosi C, Sullivan W, Shetty AP, Tucci C, Wadhwa S, Alturkistany A, Busari JO, Wang JC, Teli MGA, Rajasekaran S, Mulukutla RD, Piccirillo M, Hsieh PC, Dohring EJ, Srivastava SK, Larouche J, Vlok A, Nordin M

    Brain & spine   3   102688   2023

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  • Effect of low body mass index on clinical recovery after fusion surgery for osteoporotic vertebral fracture: A retrospective, multicenter study of 237 cases.

    Inoue G, Miyagi M, Saito W, Shirasawa E, Uchida K, Hosogane N, Watanabe K, Katsumi K, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Nojiri K, Suzuki S, Okada E, Ueda S, Hikata T, Shiono Y, Watanabe K, Terai H, Tamai K, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Ohtori S, Furuya T, Orita S, Inage K, Yoshii T, Ushio S, Funao H, Isogai N, Harimaya K, Okada S, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kiyasu K, Imagama S, Ando K, Kobayashi K, Sakai D, Tanaka M, Kimura A, Inoue H, Nakano A, Ikegami S, Shimizu M, Futatsugi T, Kakutani K, Yurube T, Nakanishi K, Oshima M, Uei H, Aoki Y, Takahata M, Iwata A, Endo H, Seki S, Murakami H, Kato S, Yoshioka K, Hongo M, Abe T, Tsukanishi T, Takaso M, Ishii K

    Medicine   101 ( 52 )   e32330   2022.12（ ISSN:0025-7974 ）

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  • Delayed aortic injury after thoracic corrective osteotomy: a case report

    Masuda Sho, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Nakamura Hiroaki

    European Spine Journal   31 ( 12 )   3703 - 3707   2022.12（ ISSN:0940-6719 ） （ eISSN:14320932 ）

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  • SPINE20 recommendations 2022: spine care-working together to recover stronger.

    Darwono B, Tamai K, Côté P, Aleissa S, Rahim AH, Pereira P, Alsobayel H, Chhabra HS, Costanzo G, Ito M, Kandziora F, Lahey D, Menezes CM, Bajammal S, Sullivan WJ, Vajkoczy P, Ahmad A, Arand M, Asmiragani S, Blattert TR, Busari J, Dohring EJ, Misaggi B, Muehlbauer EJ, Mulukutla RD, Munting E, Piccirillo M, Ruosi C, Alturkistany A, Campello M, Hsieh PC, Teli MGA, Wang JC, Nordin M

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   31 ( 12 )   3262 - 3273   2022.12（ ISSN:0940-6719 ）

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  • Prevalence, risk factors, and potential symptoms of hyponatremia after spinal surgery in elderly patients.

    Kinoshita Y, Tamai K, Oka M, Habibi H, Terai H, Hoshino M, Toyoda H, Suzuki A, Takahashi S, Nakamura H

    Scientific reports   12 ( 1 )   18622   2022.11

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  • Increased Surgical Experience in Microendoscopic Spinal Surgery Can Reduce Development of Postoperative Spinal Epidural Hematoma and Improve the Clinical Outcomes.

    Iwamae M, Tamai K, Kaneda K, Terai H, Katsuda H, Shimada N, Nakamura H

    Journal of clinical medicine   11 ( 21 )   2022.11（ ISSN:2077-0383 ）

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  • 特集 整形外科領域における人工知能の応用 各論 人工知能を活用した骨粗鬆症性椎体骨折の画像診断補助システム-MR画像における新鮮椎体骨折の識別

    藪 晋人, 星野 雅俊, 田淵 仁志, 高橋 真治, 寺井 秀富, 升本 浩紀, 前野 考史, 岩前 真由, 豊田 宏光, 鈴木 亨暢, 玉井 孝司, 猪瀬 弘之, 吉井 俊貴, 大川 淳, 中村 博亮

    臨床整形外科   57 ( 10 )   1205 - 1211   2022.10（ ISSN:05570433 ） （ eISSN:18821286 ）

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  • Does surgery improve neurological outcomes in older individuals with cervical spinal cord injury without bone injury? A multicenter study.

    Nori S, Watanabe K, Takeda K, Yamane J, Kono H, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kiyasu K, Iizuka Y, Takasawa E, Funao H, Kaito T, Yoshii T, Ishihara M, Okada S, Imagama S, Kato S

    Spinal cord   60 ( 10 )   895 - 902   2022.10（ ISSN:1362-4393 ）

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  • Factors Affecting the Waiting Time from Injury to Surgery in Elderly Patients with a Cervical Spine Injury: A Japanese Multicenter Survey.

    Uehara M, Ikegami S, Takizawa T, Oba H, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    World neurosurgery   166   e815 - e822   2022.10（ ISSN:1878-8750 ）

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  • Differences in clinical characteristics of cervical spine injuries in older adults by external causes: a multicenter study of 1512 cases.

    Yokogawa N, Kato S, Sasagawa T, Hayashi H, Tsuchiya H, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Nori S, Yamane J, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Watanabe K

    Scientific reports   12 ( 1 )   15867   2022.09

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  • Postoperative Physical Therapy Program Focused on Low Back Pain Can Improve Treatment Satisfaction after Minimally Invasive Lumbar Decompression.

    Terai H, Tamai K, Kaneda K, Omine T, Katsuda H, Shimada N, Kobayashi Y, Nakamura H

    Journal of clinical medicine   11 ( 19 )   2022.09（ ISSN:2077-0383 ）

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  • Change in Physical and Mental Quality-of-Life between the Short- and Mid-Term Periods after Cervical Laminoplasty for Cervical Spondylotic Myelopathy: A Retrospective Cohort Study with Minimum 5 Years Follow-up.

    Tamai K, Suzuki A, Terai H, Kato M, Toyoda H, Takahashi S, Yabu A, Sawada Y, Iwamae M, Nakamura H

    Journal of clinical medicine   11 ( 17 )   2022.09（ ISSN:2077-0383 ）

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  • A multicenter study of 1-year mortality and walking capacity after spinal fusion surgery for cervical fracture in elderly patients.

    Sasagawa T, Yokogawa N, Hayashi H, Tsuchiya H, Ando K, Nakashima H, Segi N, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Ikegami S, Uehara M, Suzuki H, Imajo Y, Funayama T, Eto F, Yamaji A, Hashimoto K, Onoda Y, Kakutani K, Kakiuchi Y, Suzuki N, Kato K, Terashima Y, Hirota R, Yamada T, Hasegawa T, Kawaguchi K, Haruta Y, Seki S, Tonomura H, Sakata M, Uei H, Sawada H, Tominaga H, Tokumoto H, Kaito T, Iizuka Y, Takasawa E, Oshima Y, Terai H, Tamai K, Otsuki B, Miyazaki M, Nakajima H, Nakanishi K, Misaki K, Inoue G, Kiyasu K, Akeda K, Takegami N, Yoshii T, Ishihara M, Okada S, Aoki Y, Harimaya K, Murakami H, Ishii K, Ohtori S, Imagama S, Kato S

    BMC musculoskeletal disorders   23 ( 1 )   798   2022.08

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  • Decreased daily exercise since the COVID-19 pandemic and the deterioration of health-related quality of life in the elderly population: a population-based cross-sectional study.

    Tamai K, Terai H, Takahashi S, Katsuda H, Shimada N, Habibi H, Nakamura H

    BMC geriatrics   22 ( 1 )   678   2022.08

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  • Incidence of postoperative progressive segment degeneration at decompression and adjacent segments after minimally invasive lumbar decompression surgery: a 5-year follow-up study.

    Habibi H, Toyoda H, Terai H, Yamada K, Hoshino M, Suzuki A, Takahashi S, Tamai K, Salimi H, Hori Y, Yabu A, Nakamura H

    Journal of neurosurgery. Spine   37 ( 1 )   96 - 103   2022.07

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  • SPINE20 recommendations 2021: spine care for people's health and prosperity.

    Costanzo G, Misaggi B, Ricciardi L, AlEissa SI, Tamai K, Alhelal F, Alqahtani Y, Alsobayel HI, Arand M, Balsano M, Blattert TR, Brayda-Bruno M, Busari JO, Campello M, Chhabra HS, Tamburrelli FC, Côté P, Darwono B, Kandziora F, La Maida GA, Muehlbauer EJ, Mulukutla RD, Pereira P, Rajasekaran S, Rothenfluh DA, Sullivan WJ, Truumees E, Dohring EJ, Pigott T, Shetty AP, Teli MGA, Wang JC, Ames C, Anema JR, Bang A, Cheung KMC, Gross DP, Haldeman S, Minisola S, Mullerpatan R, Negrini S, Salmi LR, Spinelli MS, Vlok A, Yankey KP, Zaina F, Alturkistany A, Franke J, Liljenqvist UR, Piccirillo M, Nordin M

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   31 ( 6 )   1333 - 1342   2022.06（ ISSN:0940-6719 ）

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  • Mid-term changes in spinopelvic sagittal alignment in lumbar spinal stenosis with coexisting degenerative spondylolisthesis or scoliosis after minimally invasive lumbar decompression surgery: minimum five-year follow-up

    Salimi Hamidullah, Toyoda Hiromitsu, Terai Hidetomi, Yamada Kentaro, Hoshino Masatoshi, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    The Spine Journal   22 ( 5 )   819 - 826   2022.05（ ISSN:1529-9430 ）

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    BACKGROUND CONTEXT : Recently, the number of patients with lumbar spinal stenosis (LSS) who present with a coexisting spinal deformity such as degenerative spondylolisthesis (DS) and scoliosis (DLS) has been increasing. Lumbar decompression without fusion can lead to a reactive improvement in the lumbar and sagittal spinopelvic alignment, even if a sagittal imbalance exists preoperatively. However, ......

    DOI： 10.1016/j.spinee.2021.11.012

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  • Facet Joint Opening on Computed Tomography Is a Predictor of Poor Clinical Outcomes After Minimally Invasive Decompression Surgery for Lumbar Spinal Stenosis.

    Yamada K, Toyoda H, Takahashi S, Tamai K, Suzuki A, Hoshino M, Terai H, Nakamura H

    Spine   47 ( 5 )   405 - 413   2022.03（ ISSN:0362-2436 ）

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  • Relationship between facet joint opening on CT and facet joint effusion on MRI in patients with lumbar spinal stenosis: analysis of a less invasive decompression procedure.

    Yamada K, Toyoda H, Takahashi S, Tamai K, Suzuki A, Hoshino M, Terai H, Nakamura H

    Journal of neurosurgery. Spine   36 ( 3 )   376 - 384   2022.03

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  • A deep learning algorithm to identify cervical ossification of posterior longitudinal ligaments on radiography.

    Tamai K, Terai H, Hoshino M, Yabu A, Tabuchi H, Sasaki R, Nakamura H

    Scientific reports   12 ( 1 )   2113   2022.02

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  • The health-related quality of life of patients with musculoskeletal disorders after the COVID-19 pandemic.

    Terai H, Tamai K, Takahashi S, Hori Y, Iwamae M, Ohyama S, Yabu A, Hoshino M, Nakamura H

    International orthopaedics   46 ( 2 )   189 - 195   2022.02（ ISSN:0341-2695 ）

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  • Impact of the COVID-19 Pandemic on Elderly Patients with Spinal Disorders.

    Terai H, Takahashi S, Tamai K, Hori Y, Iwamae M, Hoshino M, Ohyama S, Yabu A, Nakamura H

    Journal of clinical medicine   11 ( 3 )   2022.01（ ISSN:2077-0383 ）

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  • 臨床室 脊椎術後に発生した鉱質コルチコイド反応性低ナトリウム血症の1例

    木下 右貴, 玉井 孝司, 寺井 秀富, 豊田 宏光, 鈴木 亨暢, 中村 博亮

    整形外科   73 ( 1 )   28 - 31   2022.01（ ISSN:00305901 ） （ eISSN:24329444 ）

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  • Improvements in Mental Well-Being and its Predictive Factors in Patients who Underwent Cervical versus Lumbar Decompression Surgery

    Tamai Koji, Suzuki Akinobu, Toyoda Hiromitsu, Terai Hidetomi, Hoshino Masatoshi, Takahashi Shinji, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine Surgery and Related Research   6 ( 1 )   10 - 16   2022（ eISSN:2432261X ）

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    <p>Introduction: Mental well-being is essential for patient satisfaction. Therefore, a better understanding of the changes in the mental well-being of patients following spinal surgery can be useful to surgeons. We compared the 2-year postoperative change in the mental well-being of patients who underwent cervical and lumbar decompression surgery. Additionally, the predictive factors for improvement in mental well-being associated with both methods were evaluated.</p><p>Methods: The patients who underwent spinal decompression surgery and were followed >2 years postoperatively were enrolled (lumbar cohort: n=111, cervical cohort: n=121). The 36-item Short-Form Health Survey (SF-36) mental component summary (MCS) was set as the mental well-being parameter, and the minimal clinically important difference (MCID) was defined as 4.0. After adjusting the cervical and lumbar cohorts using propensity scores, the improvements in the MCS were compared between the groups using a mixed-effect model. To identify predictors for improvements, the correlation between the MCS changes and preoperative clinical scores was evaluated. Subsequently, multivariate linear regression was applied, which included variables with p<0.10 in the former analysis as explanatory variables, and the change of MCS as the objective variable.</p><p>Results: There were no significant differences in the MCS improvement between the adjusted cervical and lumbar cohorts; 47% and 49%, respectively, had MCS improvement score >MCIDs. However, predictors for the improvement were different between the two cohorts: SF-36 Social functioning in cervical surgery and lower back pain and SF-36 Role physical in lumbar surgery.</p><p>Conclusions: Although there was no significant difference in the improvement in the mental well-being between patients who underwent either cervical or lumbar decompression surgery, less than half of the patients in both groups achieved a meaningful improvement. Preoperative back pain and personal activity were independent predictors in the lumbar cohort, while social functioning was the only predictor in the cervical cohort.</p><p>Level of evidence: III</p>

    DOI： 10.22603/ssrr.2021-0060

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  • Is Blood Loss Greater in Elderly Patients under Antiplatelet or Anticoagulant Medication for Cervical Spine Injury Surgery? A Japanese Multicenter Survey

    Uehara Masashi, Ikegami Shota, Takizawa Takashi, Oba Hiroki, Yokogawa Noriaki, Sasagawa Takeshi, Ando Kei, Nakashima Hiroaki, Segi Naoki, Funayama Toru, Eto Fumihiko, Yamaji Akihiro, Watanabe Kota, Nori Satoshi, Takeda Kazuki, Furuya Takeo, Orita Sumihisa, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Terashima Yoshinori, Hirota Ryosuke, Suzuki Hidenori, Imajo Yasuaki, Tonomura Hitoshi, Sakata Munehiro, Hashimoto Ko, Onoda Yoshito, Kawaguchi Kenichi, Haruta Yohei, Suzuki Nobuyuki, Kato Kenji, Uei Hiroshi, Sawada Hirokatsu, Nakanishi Kazuo, Misaki Kosuke, Terai Hidetomi, Tamai Koji, Shirasawa Eiki, Inoue Gen, Kakutani Kenichiro, Kakiuchi Yuji, Kiyasu Katsuhito, Tominaga Hiroyuki, Tokumoto Hiroto, Iizuka Yoichi, Takasawa Eiji, Akeda Koji, Takegami Norihiko, Funao Haruki, Oshima Yasushi, Kaito Takashi, Sakai Daisuke, Yoshii Toshitaka, Ohba Tetsuro, Otsuki Bungo, Seki Shoji, Miyazaki Masashi, Ishihara Masayuki, Okada Seiji, Aoki Yasuchika, Harimaya Katsumi, Murakami Hideki, Ishii Ken, Ohtori Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   6 ( 4 )   366 - 372   2022（ eISSN:2432261X ）

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    <p>Introduction: In elderly patients with cervical spinal cord injury, comorbidities such as cardiovascular and cerebrovascular diseases are common, with frequent administration of antiplatelet/anticoagulant (APAC) drugs. Such patients may bleed easily or unexpectedly during surgery despite prior withdrawal of APAC medication. Few reports have examined the precise relationship between intraoperative blood loss and history of APAC use regarding surgery for cervical spine injury in the elderly. The present multicenter database survey aimed to answer the question of whether the use of APAC drugs affected the amount of intraoperative blood loss in elderly patients with cervical spinal cord trauma.</p><p>Methods: The case histories of 1512 patients with cervical spine injury at 33 institutes were retrospectively reviewed. After excluding cases without spinal surgery or known blood loss volume, 797 patients were enrolled. Blood volume loss was the outcome of interest. We calculated propensity scores using the inverse probability of treatment weighting (IPTW) method. As an alternative sensitivity analysis, linear mixed model analyses were conducted as well.</p><p>Results: Of the 776 patients (mean age: 75.1±6.4 years) eligible for IPTW calculation, 157 (20.2%) were taking APAC medications before the injury. After weighting, mean estimated blood loss was 204 mL for non-APAC patients and 215 mL for APAC patients. APAC use in elderly patients was not significantly associated with surgical blood loss according to the IPTW method with propensity scoring or linear mixed model analyses. Thus, it appeared possible to perform surgery expecting comparable blood loss in APAC and non-APAC cases.</p><p>Conclusions: This multicenter study revealed no significant increase in surgical blood loss in elderly patients with cervical trauma taking APAC drugs. Surgeons may be able to prioritize patient background, complications, and preexisting conditions over APAC use before injury when examining the surgical indications for cervical spine trauma in the elderly.</p>

    DOI： 10.22603/ssrr.2021-0183

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  • Clinical Comparison of Combined Cortical Bone Trajectory and Transarticular Surface Screw Versus Standard Pedicle Screw Insertion by Wiltse Approach for L5 Isthmic Spondylolisthesis

    Terai Hidetomi, Tamai Koji, Takahashi Shinji, Umano Masayuki, Iwamae Masayoshi, Toyoda Hiromitsu, Suzuki Akinobu, Hoshino Masatoshi, Nakamura Hiroaki

    Clinical Spine Surgery   34 ( 10 )   E580 - E587   2021.12（ ISSN:2380-0186 ）

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    Study Design: This was a retrospective cohort study. / Objective: The objective of this study was to assess the effectiveness and invasiveness of a combined screw insertion technique [using cortical bone trajectory (CBT) screw and transarticular surface screw (TASS)] for patients with L5 isthmic spondylolisthesis. / Summary of Background Data: Lumbosacral posterior fixation using TASS is safe, with high biomechanical strength. However, ......

    DOI： 10.1097/BSD.0000000000001170

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  • 経験と考察 新型コロナウイルス感染症(COVID-19)流行による生活様式の変化に対して運動指導を希望する整形外科患者の特徴

    馬野 雅之, 寺井 秀富, 玉井 孝司, 勝田 紘史, 島田 永和, 中村 博亮

    整形外科   72 ( 13 )   1327 - 1332   2021.12（ ISSN:00305901 ） （ eISSN:24329444 ）

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  • Characteristics and Short-Term Surgical Outcomes of Patients with Recurrent Lumbar Disc Herniation after Percutaneous Laser Disc Decompression.

    Terai H, Tamai K, Iwamae M, Kaneda K, Katsuda H, Shimada N, Nakamura H

    Medicina (Kaunas, Lithuania)   57 ( 11 )   2021.11（ ISSN:1010-660X ）

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  • Heated Tobacco Products Impair Cell Viability, Osteoblastic Differentiation, and Bone Fracture-Healing

    Nishino Kazuya, Tamai Koji, Orita Kumi, Hashimoto Yusuke, Nakamura Hiroaki

    The Journal of Bone and Joint Surgery   103 ( 21 )   2024 - 2031   2021.11（ ISSN:0021-9355 ） （ eISSN:15351386 ）

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  • Prevalence of Restless Legs Syndrome and its Symptoms among Patients with Spinal Disorders.

    Terai H, Toyoda H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Ohyama S, Yabu A, Nakamura H

    Journal of clinical medicine   10 ( 21 )   2021.10（ ISSN:2077-0383 ）

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  • Using artificial intelligence to diagnose fresh osteoporotic vertebral fractures on magnetic resonance images.

    Yabu A, Hoshino M, Tabuchi H, Takahashi S, Masumoto H, Akada M, Morita S, Maeno T, Iwamae M, Inose H, Kato T, Yoshii T, Tsujio T, Terai H, Toyoda H, Suzuki A, Tamai K, Ohyama S, Hori Y, Okawa A, Nakamura H

    The spine journal : official journal of the North American Spine Society   21 ( 10 )   1652 - 1658   2021.10（ ISSN:1529-9430 ）

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  • Clinical outcomes of laminoplasty for patients with lysosomal storage disease including mucopolysaccharidosis and mucolipidoses: a retrospective cohort study.

    Terai H, Tamai K, Hoshino M, Toyoda H, Suzuki A, Takahashi S, Hori Y, Yabu A, Nakamura H

    Orphanet journal of rare diseases   16 ( 1 )   401   2021.09

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  • Clinical Outcomes of Minimally Invasive Posterior Decompression for Lumbar Spinal Stenosis with Degenerative Spondylolisthesis

    Kobayashi Yuto, Tamai Koji, Toyoda Hiromitsu, Terai Hidetomi, Hoshino Masatoshi, Suzuki Akinobu, Takahashi Shinji, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine   46 ( 18 )   1218 - 1225   2021.09（ ISSN:0362-2436 ） （ eISSN:15281159 ）

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    Study Design: Retrospective cohort study. / Objective: To compare the clinical outcomes 5 years after minimally invasive posterior decompression for lumber spinal stenosis (LSS) between patients with and without degenerative spondylolisthesis (DS). ...

    DOI： 10.1097/BRS.0000000000003997

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  • Direct Lateral Corpectomy and Reconstruction Using an Expandable Cage Improves Local Kyphosis but Not Global Sagittal Alignment.

    Terai H, Takahashi S, Yasuda H, Konishi S, Maeno T, Kono H, Matsumura A, Namikawa T, Kato M, Hoshino M, Tamai K, Toyoda H, Suzuki A, Nakamura H

    Journal of clinical medicine   10 ( 17 )   2021.09（ ISSN:2077-0383 ）

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  • The effect of minimally invasive lumbar decompression surgery on sagittal spinopelvic alignment in patients with lumbar spinal stenosis: a 5-year follow-up study.

    Salimi H, Toyoda H, Yamada K, Terai H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Hori Y, Yabu A, Nakamura H

    Journal of neurosurgery. Spine   35 ( 2 )   177 - 184   2021.08

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  • Can Conventional Magnetic Resonance Imaging Substitute Three-Dimensional Magnetic Resonance Imaging in the Diagnosis of Lumbar Foraminal Stenosis?

    Hasib MM, Yamada K, Hoshino M, Yamada E, Tamai K, Takahashi S, Suzuki A, Toyoda H, Terai H, Nakamura H

    Asian spine journal   15 ( 4 )   472 - 480   2021.08（ ISSN:1976-1902 ）

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  • SPINE20 A global advocacy group promoting evidence-based spine care of value.

    AlEissa SI, Tamai K, Konbaz F, Alturkistany A, Blattert TR, Chhabra HS, Costanzo G, Dohring EJ, Kandziora F, Kothe R, Misaggi B, Muehlbauer EJ, Pereira P, Rajasekaran S, Sullivan WJ, Truumees E, Alqahtani Y, Alsobayel HI, Franke J, Teli MGA, Wang JC, Al-Hazzaa HM, Alosaimi MN, Berven S, Brayda-Bruno M, Briggs AM, Busari JO, Caserta AV, Côté P, Crostelli M, Fehlings MG, Gunzburg R, Haddadin S, Ihm J, Hilibrand AS, Luca A, Osvaldo M, Pigott T, Rothenfluh DA, Ruosi C, Salmi LR, Shetty AP, Singh K, Vaccaro AR, Wong DA, Zileli M, Nordin M

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   30 ( 8 )   2091 - 2101   2021.08（ ISSN:0940-6719 ）

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  • Differences in surgical outcome after anterior corpectomy and reconstruction with an expandable cage with rectangular footplates between thoracolumbar and lumbar osteoporotic vertebral fracture.

    Terai H, Takahashi S, Yasuda H, Konishi S, Maeno T, Kono H, Matsumura A, Namikawa T, Kato M, Hoshino M, Tamai K, Toyoda H, Suzuki A, Nakamura H

    North American Spine Society journal   6   100071   2021.06

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  • Expression and function of FGF9 in the hypertrophied ligamentum flavum of lumbar spinal stenosis patients.

    Habibi H, Suzuki A, Hayashi K, Salimi H, Terai H, Hori Y, Tamai K, Orita K, Ohyama S, Yabu A, Maruf MH, Nakamura H

    The spine journal : official journal of the North American Spine Society   21 ( 6 )   1010 - 1020   2021.06（ ISSN:1529-9430 ）

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  • Risk Factor for Poor Patient Satisfaction After Lumbar Spine Surgery in Elderly Patients Aged Over 80 years.

    Hikata T, Ishii K, Matsumoto M, Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Endo K, Suzuki H, Nakano A, Watanabe K, Ohya J, Chikuda H, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Kobayashi R, Iizuka Y, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Abe T, Fujii K, Kaito T, Eguchi Y, Furuya T, Orita S, Ohtori S

    Clinical spine surgery   34 ( 4 )   E223 - E228   2021.05（ ISSN:2380-0186 ）

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  • Classification and prognostic factors of residual symptoms after minimally invasive lumbar decompression surgery using a cluster analysis: a 5-year follow-up cohort study

    Toyoda Hiromitsu, Yamada Kentaro, Terai Hidetomi, Hoshino Masatoshi, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Ohyama Shoichiro, Hori Yusuke, Yabu Akito, Salimi Hamidullah, Nakamura Hiroaki

    European Spine Journal   30 ( 4 )   918 - 927   2021.04（ ISSN:0940-6719 ） （ eISSN:14320932 ）

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    Purpose: Residual symptoms indicating incomplete remission of lower leg numbness or low back pain may occur after spine surgery. The purpose was to elucidate the pattern of residual symptoms 5 years after minimally invasive lumbar decompression surgery using a cluster analysis. ...

    DOI： 10.1007/s00586-021-06754-y

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  • Biglycan expression and its function in human ligamentum flavum.

    Salimi H, Suzuki A, Habibi H, Orita K, Hori Y, Yabu A, Terai H, Tamai K, Nakamura H

    Scientific reports   11 ( 1 )   4867   2021.03

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  • Time Course of Physical and Mental Well-being Improvements After Cervical Surgery

    Tamai Koji, Suzuki Akinobu, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Takahashi Shinji, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine   46 ( 5 )   E303 - E309   2021.03（ ISSN:0362-2436 ） （ eISSN:15281159 ）

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    Study Design: Retrospective cohort study. / Objective: To elucidate the postoperative time course of improvements in physical and mental well-being in patients with cervical spondylotic myelopathy (CSMI. …

    DOI： 10.1097/BRS.0000000000003787

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  • Impact of High-intensity Zones on Their Corresponding Lumbar Spine Segments: A Propensity Score-matched Analysis.

    Chen X, Tamai K, Yang JJ, Shah ID, Paholpak P, Wang JC, Buser Z

    Clinical spine surgery   34 ( 1 )   32 - 38   2021.02（ ISSN:2380-0186 ）

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  • The short-term outcomes of minimally invasive decompression surgery in patients with lumbar ossification or calcification of the ligamentum flavum.

    Tamai K, Kaneda K, Iwamae M, Terai H, Katsuda H, Shimada N, Nakamura H

    Journal of neurosurgery. Spine   34 ( 2 )   203 - 210   2021.02

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  • Presence of sarcopenia does not affect the clinical results of balloon kyphoplasty for acute osteoporotic vertebral fracture.

    Ohyama S, Hoshino M, Takahashi S, Hori Y, Yasuda H, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Toyoda H, Dohzono S, Nakamura H

    Scientific reports   11 ( 1 )   122   2021.01

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  • Percutaneous Endovascular Retrieval of Large Cement Leakage into the Right Atrium Following Cement-Augmented Pedicle Screw Instrumentation

    Takahashi Shinji, Sohgawa Etsuji, Suzuki Akinobu, Yamamoto Akira, Sasaki Ryo, Tanaka Katsuaki, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Tamai Koji, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 6 )   446 - 449   2021（ eISSN:2432261X ）

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  • Surgical Outcomes of a New Technique Using a Convex Rod Rotation Maneuver for Adolescent Idiopathic Scoliosis

    Takahashi Shinji, Terai Hidetomi, Toyoda Hiromitsu, Hoshino Masatoshi, Suzuki Akinobu, Tamai Koji, Ohyama Shoichiro, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 3 )   205 - 210   2021（ eISSN:2432261X ）

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    <p>Introduction: Because of adolescent idiopathic scoliosis (AIS), most surgeons use rod rotation on the concave side for Lenke types 1 and 2 curves. Nevertheless, the accurate placement of pedicle screws within dysplastic pedicles, especially on the concave side, is sometimes challenging. Conversely, there is a concern that apical rotation might be exacerbated after convex rod rotation maneuver (RRM) because the rod is rotated in the same direction as vertebral rotation. This study aims to demonstrate the surgical technique and outcomes of a convex RRM with direct vertebral rotation (DVR) for the correction of AIS.</p><p>Technical Note: Multilevel pedicle screws were inserted into the vertebrae. The pre-bent pure titanium rod was set on the convex side and then derotated to nearly 90°. DVR was conducted for the desired vertebrae. Another pre-bent titanium alloy rod, for placement on the concave side, was contoured the same as the rod on the convex side. Using a reduction tube that allowed easier capture of the rod, the rod was connected to the concave side screws. DVR was again conducted for the desired vertebrae. Among the 59 patients, the correction rate of the main thoracic curve in Lenke types 1 and 2 AIS was 75.1% and 65.0%, respectively. The absolute value of the change in apical vertebral rotation between pre- and post-operative computed tomography (CT) scans in Lenke types 1 and 2 curves was 4.8° and 4.2°, respectively.</p><p>Conclusions: The convex RRM improved vertebral rotation in Lenke types 1 and 2 AIS. This procedure should be regarded as one of the surgical options for AIS, especially in patients with a narrow pedicle width on the concave side.</p>

    DOI： 10.22603/ssrr.2020-0185

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  • Reductions in the Frequency of Going Out Due to the COVID-19 Pandemic Negatively Affect Patients with Spinal Disorders

    Terai Hidetomi, Iwamae Masayoshi, Tamai Koji, Takahashi Shinji, Hori Yusuke, Ohyama Shoichiro, Yabu Akito, Hoshino Masatoshi, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 6 )   365 - 374   2021（ eISSN:2432261X ）

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    <p>Introduction: The coronavirus disease 2019 (COVID-19) pandemic has greatly changed the lifestyles of individuals due to the need to prevent disease spread. Globally, governments have enforced various policies, including travel bans, quarantine, home confinement, and lockdowns, as safety measures. Consequently, the frequency of individuals going out has decreased. This survey aimed to assess how decreasing the frequency of going out due to the COVID-19 pandemic impacts patients with spinal disorders.</p><p>Methods: This multicenter cross-sectional questionnaire survey included patients who visited four private spine clinics for any symptoms. Participants completed questionnaires pre- and post-pandemic that assessed the following topics: frequency of leaving home, exercise habits, locomotive syndrome, and health-related quality of life (HRQOL). Patients were divided into decreased and non-decreased frequency of going out groups, according to observed changes in their frequencies of leaving home. Both groups were statistically compared using univariate and multivariate logistic regression analyses to identify factors associated with the frequency of going out.</p><p>Results: Among 855 patients, 160 (18.7%; the decreased group) reported that they went out less frequently, and 695 (81.3%; the non-decreased group) reported that they left home equally frequently post- versus pre-pandemic. Multivariate analyses showed that exercise habits significantly decreased (adjusted odds ratio (aOR) = 2.67, p = 0.004), the incidence of locomotive syndrome significantly increased (aOR = 2.86, p = 0.012), and HRQOL significantly deteriorated (aOR = 4.14, p < 0.001) in the decreased group compared to the non-decreased group.</p><p>Conclusions: Restrictions regarding leaving home due to the COVID-19 pandemic significantly decreased exercise frequency, increased the occurrence of locomotive syndrome, and were associated with deterioration of HRQOL in patients with spine disorders. It may be beneficial for spine surgeons to encourage patients with spinal disorders to leave home at a frequency similar to what they did pre-pandemic while avoiding crowded areas, despite the presence of the COVID-19 pandemic.</p>

    DOI： 10.22603/ssrr.2021-0088

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  • Do rheumatoid arthritis patients have low back pain or radiological lumbar lesions more frequently than the healthy population? : Cross-sectional analysis in a cohort study with age and sex-matched healthy volunteers

    Suzuki Akinobu, Tamai Koji, Takahashi Shinji, Yamada Kentaro, Inui Kentaro, Tada Masahiro, Okano Tadashi, Sugioka Yuko, Koike Tatsuya, Nakamura Hiroaki

    The Spine Journal   20 ( 12 )   1995 - 2002   2020.12（ ISSN:1529-9430 ）

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    BACKGROUND CONTEXT: Rheumatoid arthritis (RA) can affect the spine; however, the epidemiology of lumbar lesions and/or low back pain (LBP) in RA patients has not been well-studied. / PURPOSE: The purpose of this study was to compare the prevalence of lumbar lesions and LBP in RA patients with that in healthy volunteers, and to elucidate the influence of RA on lumbar disease....

    DOI： 10.1016/j.spinee.2020.06.020

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  • The Severity of Cervical Disc Degeneration Does Not Impact 2-year Postoperative Outcomes in Patients With Cervical Spondylotic Myelopathy Who Underwent Laminoplasty

    Habibi Hasibullah, Suzuki Akinobu, Tamai Koji, Ohyama Shoichiro, Hori Yusuke, Yabu Akito, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Takahashi Shinji, Ahmadi Sayed Abdullah, Nakamura Hiroaki

    Spine   45 ( 18 )   E1142 - E1149   2020.09（ ISSN:0362-2436 ） （ eISSN:15281159 ）

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    Study Design: Retrospective cohort study. / Objective: The aim of this study was to evaluate the impact of cervical disc degeneration (CDD) severity on 2-year postoperative outcomes following laminoplasty. / Summary of Background Data: The impact of CDD on postoperative outcomes of cervical laminoplasty has not been well established....

    DOI： 10.1097/BRS.0000000000003528

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  • Short- versus long-segment posterior spinal fusion with vertebroplasty for osteoporotic vertebral collapse with neurological impairment in thoracolumbar spine: a multicenter study.

    Ishikawa Y, Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Izumi T, Hirano T, Endo N, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    BMC musculoskeletal disorders   21 ( 1 )   513   2020.08

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  • Effect of bisphosphonates or teriparatide on mechanical complications after posterior instrumented fusion for osteoporotic vertebral fracture: a multi-center retrospective study.

    Kawabata A, Yoshii T, Hirai T, Ushio S, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    BMC musculoskeletal disorders   21 ( 1 )   420   2020.07

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  • The factors related to the poor ADL in the patients with osteoporotic vertebral fracture after instrumentation surgery.

    Murata K, Matsuoka Y, Nishimura H, Endo K, Suzuki H, Takamatsu T, Sawaji Y, Aihara T, Kusakabe T, Maekawa A, Yamamoto K, Watanabe K, Kaito T, Terai H, Tamai K, Tagami A, Yoshii T, Harimaya K, Kawaguchi K, Kimura A, Inoue G, Nakano A, Sakai D, Hiyama A, Ikegami S, Ohtori S, Furuya T, Orita S, Imagama S, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Uei H, Ajiro Y, Takahata M, Endo H, Abe T, Nakanishi K, Watanabe K, Okada E, Hosogane N, Funao H, Isogai N, Ishii K

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   29 ( 7 )   1597 - 1605   2020.07（ ISSN:0940-6719 ）

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  • Facet joint opening on preoperative computed tomography is risk factor for revision surgery after less invasive decompression procedure for lumbar spinal stenosis

    Yamada Kentaro, Toyoda Hiromitsu, Tamai Koji, Takahashi Shinji, Suzuki Akinobu, Hoshino Masatoshi, Terai Hidetomi, Nakamura Hiroaki

    Journal of Spine Research   11 ( 6 )   936 - 941   2020.06（ ISSN:18847137 ） （ eISSN:24351563 ）

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    <p><b>Purpose: </b>There is no consensus of regarding the indication of surgical treatment of the less invasive decompression procedure for lumbar spinal stenosis (LSS). Although facet joint opening (FO) on preoperative computed tomography (CT) images has been reported as a parameter indicating segmental instability, there is no report on how FO affects on postoperative outcomes. The purpose of this study was to investigate risk factors for revision surgery after less invasive decompression surgery for LSS including FO by a minimum-5-year postoperative survey.</p><p><b>Materials and Methods: </b>A total of 244 patients who underwent microscopic or microendoscopic decompression surgery for LSS and followed for ≥5 years were included in this study. We investigated revision lumbar surgeries at the same levels or other lumbar levels based on medical records. Revision surgeries due to postoperative hematoma or infection were excluded. FO was defined as a ≥2 mm opening on preoperative axial CT images at each lumbar intervertebral level. We evaluated the FO at index decompression levels and sum of FO-positive levels from L1-2 to L5-S. Risk factors for further surgeries were investigated among demographics, preoperative symptoms, and radiological parameters other than FO using univariate and cox proportional hazard regression analysis.</p><p><b>Results: </b>There was 26 reoperations (10.7%) at a mean of 3.9 years after primary surgeries. FO at index decompression levels was significantly more frequent in patients with than without revision surgeries (69 and 39%, respectively, p=0.003). The sum of FO-positive levels among lumbar segments was significantly higher in patients with than without revision surgeries (2.0 and 1.2 levels, respectively, p=0.001). The cox proportional hazard regression analysis indicated that the sum of FO-positive levels among lumbar segments was one of the risk factors for revision surgery (p=0.003, adjusted hazard ratio: 1.47).</p><p><b>Conclusions: </b>The FO of index decompression levels and sum of FO were associated with the need for further lumbar surgeries after less invasive surgery. FO might indicate not only segmental instability but also predictive parameter for progression of degenerative change.</p>

    DOI： 10.34371/jspineres.2020-0512

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  • Improvement in Patient Mental Well-being After Surgery for Cervical Spondylotic Myelopathy

    Tamai Koji, Suzuki Akinobu, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Takahashi Shinji, Ohyama Shoichiro, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine   45 ( 10 )   E568 - E575   2020.05（ ISSN:0362-2436 ） （ eISSN:15281159 ）

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    Study Design: Retrospective cohort study. / Objective: The aim of this study was to investigate changes in mental well-being after surgery for cervical spondylotic myelopathy (CSM) and identify factors associated with improvement….

    DOI： 10.1097/BRS.0000000000003337

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  • Clinical Impact of Cervical Imbalance on Surgical Outcomes of Laminoplasty: A Propensity Score-Matching Analysis.

    Tamai K, Suzuki A, Yabu A, Terai H, Hoshino M, Toyoda H, Takahashi S, Ohyama S, Hori Y, Nakamura H

    Clinical spine surgery   33 ( 1 )   E1 - E7   2020.02（ ISSN:2380-0186 ）

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  • The effect of nicotine cessation on human bone marrow stem cell proliferation and differentiation into osteoblasts.

    Tamai K, Formanek B, Chamnan R, Wang JC, Buser Z

    The spine journal : official journal of the North American Spine Society   20 ( 2 )   307 - 309   2020.02（ ISSN:1529-9430 ）

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  • Patient-reported outcomes for cervical disease in end-stage renal disease patients: Propensity matching analysis using volunteer data

    Tamai Koji, Yabu Akito, Takayama Kazushi, Kita Teruo, Sakanaka Hideki, Suzuki Akinobu, Nakamura Hiroaki

    Journal of Clinical Neuroscience   72   130 - 133   2020.02（ ISSN:0967-5868 ）

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    As the number of patients with end-stage renal disease (ESRD) has been increasing, the number of cervical spine surgeries for the patients with ESRD has also been increasing. The purpose is to identify the differences in cervical disease-specific patient-reported outcomes (PROs) between a healthy population and patients with ESRD, adjusting for subjects' age and physical activity. / [Methods] The ESRD group included patients with ESRD who were treated with hemodialysis in our outpatient clinic and healthy volunteers were individuals who attended public health lectures. Volunteers with a history of cervical disease were excluded. All participants answered the Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire (JOACMEQ) and questionnaires that evaluate the disability in performing physical activities....

    DOI： 10.1016/j.jocn.2019.12.045

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  • Reply to the Editor: Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit-A Nationwide Multicenter Study in Japan

    Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Funao Haruki, Okada Eijiro, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshio, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   4 ( 3 )   292 - 293   2020（ eISSN:2432261X ）

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  • The Surgical Outcomes of Spinal Fusion for Osteoporotic Vertebral Fractures in the Lower Lumbar Spine with a Neurological Deficit

    Isogai Norihiro, Hosogane Naobumi, Funao Haruki, Nojiri Kenya, Suzuki Satoshi, Okada Eijiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Shuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   4 ( 3 )   199 - 207   2020（ eISSN:2432261X ）

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    <p>Introduction: Osteoporotic vertebral fracture (OVF) is the most common osteoporotic fracture, and some patients require surgical intervention to improve their impaired activities of daily living with neurological deficits. However, many previous reports have focused on OVF around the thoracolumbar junction, and the surgical outcomes of lumbar OVF have not been thoroughly discussed. We aimed to investigate the surgical outcomes for lumbar OVF with a neurological deficit.</p><p>Methods: Patients who underwent fusion surgery for thoracolumbar OVF with a neurological deficit were enrolled at 28 institutions. Clinical information, comorbidities, perioperative complications, Japanese Orthopaedic Association scores, visual analog scale scores, and radiographic parameters were compared between patients with lower lumbar fracture (L3-5) and those with thoracolumbar junction fracture (T10-L2). Each patient with lower lumbar fracture (L group) was matched with to patients with thoracolumbar junction fracture (T group).</p><p>Results: A total 403 patients (89 males and 314 females, mean age: 73.8 ± 7.8 years, mean follow-up: 3.9 ± 1.7 years) were included in this study. Lower lumbar OVF was frequently found in patients with lower bone mineral density. After matching, mechanical failure was more frequent in the L group (L group: 64%, T group: 39%; p < 0.001). There was no difference between groups in the clinical and radiographical outcomes, although the rates of complication and revision surgery were still high in both groups.</p><p>Conclusions: The surgical intervention for OVF is effective in patients with myelopathy or radiculopathy regardless of the surgical level, although further study is required to improve clinical and radiographical outcomes.</p><p>Level of evidence: Level III</p>

    DOI： 10.22603/ssrr.2019-0079

    PubMed

    CiNii Research

  • Characteristic radiological findings for revision surgery after balloon kyphoplasty.

    Takahashi S, Hoshino M, Yasuda H, Hori Y, Ohyama S, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Toyoda H, Dohzono S, Sasaoka R, Kanematsu F, Terakawa M, Nakamura H

    Scientific reports   9 ( 1 )   18513   2019.12

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  • Impact of Sarcopenia on Clinical Outcomes of Minimally Invasive Lumbar Decompression Surgery.

    Toyoda H, Hoshino M, Ohyama S, Terai H, Suzuki A, Yamada K, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    Scientific reports   9 ( 1 )   16619   2019.11

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  • Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study.

    Sakai Y, Kaito T, Takenaka S, Yamashita T, Makino T, Hosogane N, Nojiri K, Suzuki S, Okada E, Watanabe K, Funao H, Isogai N, Ueda S, Hikata T, Shiono Y, Watanabe K, Katsumi K, Fujiwara H, Nagamoto Y, Terai H, Tamai K, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Ohtori S, Orita S, Furuya T, Yoshii T, Ushio S, Inoue G, Miyagi M, Saito W, Imagama S, Ando K, Sakai D, Nukaga T, Kiyasu K, Kimura A, Inoue H, Nakano A, Harimaya K, Doi T, Kawaguchi K, Yokoyama N, Oishi H, Ikegami S, Futatsugi T, Shimizu M, Kakutani K, Yurube T, Oshima M, Uei H, Aoki Y, Takahata M, Iwata A, Seki S, Murakami H, Yoshioka K, Endo H, Hongo M, Nakanishi K, Abe T, Tsukanishi T, Ishii K

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 6 )   985 - 990   2019.11（ ISSN:0949-2658 ）

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  • Surgical outcomes of spinal fusion for osteoporotic vertebral fracture in the thoracolumbar spine: Comprehensive evaluations of 5 typical surgical fusion techniques.

    Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Hirano T, Endo N, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 6 )   1020 - 1026   2019.11（ ISSN:0949-2658 ）

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  • Fibroblast Growth Factor 9 Is Upregulated Upon Intervertebral Mechanical Stress-Induced Ligamentum Flavum Hypertrophy in a Rabbit Model.

    Hayashi K, Suzuki A, Terai H, Ahmadi SA, Rahmani MS, Maruf MH, Habibi H, Hori Y, Yamada K, Hoshino M, Toyoda H, Takahashi S, Tamai K, Ohyama S, Imai Y, Nakamura H

    Spine   44 ( 20 )   E1172 - E1180   2019.10（ ISSN:0362-2436 ）

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  • Increased advanced glycation end products in hypertrophied ligamentum flavum of diabetes mellitus patients.

    Maruf MH, Suzuki A, Hayashi K, Habibi H, Salimi H, Terai H, Tamai K, Hoshino M, Toyoda H, Yamada K, Takahashi S, Ohyama S, Hori Y, Nakamura H

    The spine journal : official journal of the North American Spine Society   19 ( 10 )   1739 - 1745   2019.10（ ISSN:1529-9430 ）

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  • The most appropriate cervical vertebra for the measurement of occipitocervical inclination parameter: a validation study of C3, C4, and C5 levels using multi-positional magnetic resonance imaging.

    Paholpak P, Formanek B, Vega A, Tamai K, Buser Z, Wang JC

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 10 )   2325 - 2332   2019.10（ ISSN:0940-6719 ）

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  • Sarcopenia is related to spinal sagittal imbalance in patients with spinopelvic mismatch.

    Ohyama S, Hoshino M, Terai H, Toyoda H, Suzuki A, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 9 )   1929 - 1936   2019.09（ ISSN:0940-6719 ）

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  • Development of a scoring system for predicting adjacent vertebral fracture after balloon kyphoplasty.

    Takahashi S, Hoshino M, Yasuda H, Hori Y, Ohyama S, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Toyoda H, Dohzono S, Sasaoka R, Kanematsu F, Nakamura H

    The spine journal : official journal of the North American Spine Society   19 ( 7 )   1194 - 1201   2019.07（ ISSN:1529-9430 ）

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  • Answer to the Letter to the Editor concerning "The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders" by Toyoda H, et al. (Eur Spine J; doi.org/10.1007/s00586-018-5858-8).

    Toyoda H, Hoshino M, Ohyama S, Terai H, Suzuki A, Yamada K, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 5 )   1252 - 1253   2019.05（ ISSN:0940-6719 ）

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  • The Impact of Cervical Spinal Muscle Degeneration on Cervical Sagittal Balance and Spinal Degenerative Disorders.

    Tamai K, Grisdela P Jr, Romanu J, Paholpak P, Nakamura H, Wang JC, Buser Z

    Clinical spine surgery   32 ( 4 )   E206 - E213   2019.05（ ISSN:2380-0186 ）

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  • Kinematic characteristics of patients with cervical imbalance: a weight-bearing dynamic MRI study.

    Tamai K, Grisdela P Jr, Romanu J, Paholpak P, Buser Z, Wang JC

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 5 )   1200 - 1208   2019.05（ ISSN:0940-6719 ）

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  • Impact of Hemodialysis on Surgical Outcomes and Mortality Rate after Lumbar Spine Surgery: A Matched Cohort Study.

    Hori Y, Takahashi S, Terai H, Hoshino M, Toyoda H, Suzuki A, Hayashi K, Tamai K, Ohyama S, Nakamura H

    Spine surgery and related research   3 ( 2 )   151 - 156   2019.04

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  • Risk Factors for Proximal Junctional Fracture Following Fusion Surgery for Osteoporotic Vertebral Collapse with Delayed Neurological Deficits: A Retrospective Cohort Study of 403 Patients.

    Tamai K, Terai H, Suzuki A, Nakamura H, Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Izumi T, Hirano T, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    Spine surgery and related research   3 ( 2 )   171 - 177   2019.04

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  • Kinematic evaluation of thoracic spinal cord sagittal diameter and the space available for cord using weight-bearing kinematic magnetic resonance imaging.

    Paholpak P, Abedi A, Chamnan R, Chantarasirirat K, Tamai K, Buser Z, Wang JC

    Spinal cord   57 ( 4 )   276 - 281   2019.04（ ISSN:1362-4393 ）

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  • Reliability and Validity of the AOSpine Thoracolumbar Injury Classification System: A Systematic Review.

    Abedi A, Mokkink LB, Zadegan SA, Paholpak P, Tamai K, Wang JC, Buser Z

    Global spine journal   9 ( 2 )   231 - 242   2019.04（ ISSN:2192-5682 ）

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  • Prevention of Nerve Root Thermal Injury Caused by Bipolar Cauterization Near the Nerve Roots.

    Ohyama S, Takahashi S, Tamai K, Hori Y, Hirakawa Y, Hoshino M, Suzuki A, Nakamura H

    Spine   44 ( 6 )   E321 - E328   2019.03（ ISSN:0362-2436 ）

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  • Surgical outcomes of spinal fusion for osteoporotic thoracolumbar vertebral fractures in patients with Parkinson's disease: what is the impact of Parkinson's disease on surgical outcome?

    Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Izumi T, Hirano T, Endo N, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    BMC musculoskeletal disorders   20 ( 1 )   103   2019.03

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  • Cost-effectiveness of Balloon Kyphoplasty for Patients With Acute/Subacute Osteoporotic Vertebral Fractures in the Super-Aging Japanese Society.

    Takahashi S, Hoshino M, Yasuda H, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Ohyama S, Toyoda H, Dohzono S, Kanematsu F, Hori Y, Nakamura H

    Spine   44 ( 5 )   E298 - E305   2019.03（ ISSN:0362-2436 ）

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  • Perioperative Catheter Use as a Risk Factor for Surgical Site Infection After Cervical Surgery: An Analysis of 39,893 Patients.

    Tamai K, Wang C, Heindel P, Paholpak P, Buser Z, Wang JC

    Spine   44 ( 3 )   E157 - E161   2019.02（ ISSN:0362-2436 ）

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  • Preoperative severity of facet joint degeneration does not impact the 2-year clinical outcomes and cervical imbalance following laminoplasty.

    Tamai K, Suzuki A, Yabu A, Takahashi S, Toyoda H, Hoshino M, Terai H, Nakamura H

    The spine journal : official journal of the North American Spine Society   19 ( 2 )   246 - 252   2019.02（ ISSN:1529-9430 ）

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  • The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders.

    Toyoda H, Hoshino M, Ohyama S, Terai H, Suzuki A, Yamada K, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 2 )   241 - 249   2019.02（ ISSN:0940-6719 ）

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  • Balloon Kyphoplasty Versus Conservative Treatment for Acute Osteoporotic Vertebral Fractures With Poor Prognostic Factors: Propensity Score Matched Analysis Using Data From Two Prospective Multicenter Studies.

    Hoshino M, Takahashi S, Yasuda H, Terai H, Watanabe K, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Ohyama S, Toyoda H, Dohzono S, Kanematsu F, Hori Y, Nakamura H

    Spine   44 ( 2 )   110 - 117   2019.01（ ISSN:0362-2436 ）

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  • Anatomical analysis of the human ligamentum flavum in the thoracic spine: Clinical implications for posterior thoracic spinal surgery.

    Ahmadi SA, Suzuki A, Terai H, Tamai K, Akhgar J, Hoshino M, Toyoda H, Rahmani MS, Hayashi K, Ohyama S, Takahashi S, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 1 )   62 - 67   2019.01（ ISSN:0949-2658 ）

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  • Evaluation of foraminal cross-sectional area in lumbar spondylolisthesis using kinematic MRI.

    Paholpak P, Nazareth A, Khan YA, Khan SU, Ansari F, Tamai K, Buser Z, Wang JC

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie   29 ( 1 )   17 - 23   2019.01（ ISSN:1633-8065 ）

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  • Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit-A Nationwide Multicenter Study in Japan.

    Hosogane N, Nojiri K, Suzuki S, Funao H, Okada E, Isogai N, Ueda S, Hikata T, Shiono Y, Watanabe K, Watanabe K, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Terai H, Tamai K, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Ohtori S, Orita S, Furuya T, Yoshii T, Ushio S, Inoue G, Miyagi M, Saito W, Imagama S, Ando K, Sakai D, Nukaga T, Kiyasu K, Kimura A, Inoue H, Nakano A, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Ikegami S, Shimizu M, Futatsugi T, Kakutani K, Yurube T, Oshima M, Uei H, Aoki Y, Takahata M, Iwata A, Seki S, Murakami H, Yoshioka K, Endo H, Hongo M, Nakanishi K, Abe T, Tsukanishi T, Ishii K

    Spine surgery and related research   3 ( 4 )   361 - 367   2019

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  • Comparison of minimally invasive decompression and combined minimally invasive decompression and fusion in patients with degenerative spondylolisthesis with instability.

    Hayashi K, Toyoda H, Terai H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Ohyama S, Hori Y, Yabu A, Nakamura H

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   57   79 - 85   2018.11（ ISSN:0967-5868 ）

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  • Small C7-T1 lordotic angle and muscle degeneration at C7 level were independent radiological characteristics of patients with cervical imbalance: a propensity score-matched analysis.

    Tamai K, Romanu J, Grisdela P Jr, Paholpak P, Zheng P, Nakamura H, Buser Z, Wang JC

    The spine journal : official journal of the North American Spine Society   18 ( 9 )   1505 - 1512   2018.09（ ISSN:1529-9430 ）

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  • Can multi-positional magnetic resonance imaging be used to evaluate angular parameters in cervical spine? A comparison of multi-positional MRI to dynamic plain radiograph.

    Paholpak P, Tamai K, Shoell K, Sessumpun K, Buser Z, Wang JC

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   27 ( 5 )   1021 - 1027   2018.05（ ISSN:0940-6719 ）

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  • The evaluation of lumbar paraspinal muscle quantity and quality using the Goutallier classification and lumbar indentation value.

    Tamai K, Chen J, Stone M, Arakelyan A, Paholpak P, Nakamura H, Buser Z, Wang JC

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   27 ( 5 )   1005 - 1012   2018.05（ ISSN:0940-6719 ）

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  • MRI kinematic analysis of T1 sagittal motion between cervical flexion and extension positions in 145 patients.

    Tamai K, Buser Z, Paholpak P, Sessumpun K, Hsieh PC, Nakamura H, Wang JC

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   27 ( 5 )   1034 - 1041   2018.05（ ISSN:0940-6719 ）

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  • Characteristics of Cervical Spine Motion in Different Types of Cervical Alignment: Kinematic MRI Study.

    Sessumpun K, Paholpak P, Hindoyan KN, Tamai K, Sangkomkamhang T, Buser Z, Wang JC

    Clinical spine surgery   31 ( 4 )   E239 - E244   2018.05（ ISSN:2380-0186 ）

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  • Can C7 Slope Substitute the T1 slope?: An Analysis Using Cervical Radiographs and Kinematic MRIs.

    Tamai K, Buser Z, Paholpak P, Sessumpun K, Nakamura H, Wang JC

    Spine   43 ( 7 )   520 - 525   2018.04（ ISSN:0362-2436 ）

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  • Predictive factors for osteochondritis dissecans of the lateral femoral condyle concurrent with a discoid lateral meniscus.

    Takigami J, Hashimoto Y, Tomihara T, Yamasaki S, Tamai K, Kondo K, Nakamura H

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA   26 ( 3 )   799 - 805   2018.03（ ISSN:0942-2056 ）

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  • Validity and Reproducibility of Various Measurement Methods for Craniocervical Sagittal Balance.

    Tamai K, Suzuki A, Takahashi S, Hoshino M, Toyoda H, Hayashi K, Ohyama S, Kishimura Y, Onode E, Umano M, Terai H, Nakamura H

    Clinical spine surgery   31 ( 2 )   80 - 85   2018.03（ ISSN:2380-0186 ）

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  • Differences in short-term clinical and radiological outcomes depending on timing of balloon kyphoplasty for painful osteoporotic vertebral fracture.

    Takahashi S, Hoshino M, Terai H, Toyoda H, Suzuki A, Tamai K, Watanabe K, Tsujio T, Yasuda H, Kono H, Sasaoka R, Dohzono S, Hayashi K, Ohyama S, Hori Y, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   23 ( 1 )   51 - 56   2018.01（ ISSN:0949-2658 ）

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  • The primary diagnosis and the coexisting anxiety disorders have no impact on the additional surgical procedure after spinal cord stimulators implantation: An analysis of 11,029 patients.

    Tamai K, Buser Z, Wang C, Paholpak P, Nakamura H, Wang JC, Hsieh PC

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   47   208 - 213   2018.01（ ISSN:0967-5868 ）

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  • Anatomical analysis of human ligamentum flavum in the cervical spine: Special consideration to the attachments, coverage, and lateral extent.

    Rahmani MS, Terai H, Akhgar J, Suzuki A, Toyoda H, Hoshino M, Tamai K, Ahmadi SA, Hayashi K, Takahashi S, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   22 ( 6 )   994 - 1000   2017.11（ ISSN:0949-2658 ）

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  • Mechanical stress induces elastic fibre disruption and cartilage matrix increase in ligamentum flavum.

    Hayashi K, Suzuki A, Abdullah Ahmadi S, Terai H, Yamada K, Hoshino M, Toyoda H, Takahashi S, Tamai K, Ohyama S, Javid A, Suhrab Rahmani M, Hasib MM, Nakamura H

    Scientific reports   7 ( 1 )   13092   2017.10

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  • Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study.

    Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Nishimura H, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S

    Global spine journal   7 ( 7 )   636 - 641   2017.10（ ISSN:2192-5682 ）

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  • Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study.

    Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Matsuoka Y, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S

    Global spine journal   7 ( 6 )   560 - 566   2017.09（ ISSN:2192-5682 ）

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  • Anterior Cervical Discectomy and Fusion Provides Better Surgical Outcomes Than Posterior Laminoplasty in Elderly Patients With C3-4 Level Myelopathy.

    Tamai K, Terai H, Suzuki A, Toyoda H, Hoshino M, Takahashi S, Hayashi K, Ohyama S, Nakamura H

    Spine   42 ( 8 )   548 - 555   2017.04（ ISSN:0362-2436 ）

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  • Incidence of Pleural Fluid and Its Associated Risk Factors After Posterior Spinal Fusion in Patients With Adolescent Idiopathic Scoliosis.

    Hayashi K, Terai H, Toyoda H, Suzuki A, Hoshino M, Tamai K, Ohyama S, Nakamura H

    Spine   42 ( 8 )   603 - 609   2017.04（ ISSN:0362-2436 ）

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  • Cervical lordotic alignment following posterior spinal fusion for adolescent idiopathic scoliosis: reciprocal changes and risk factors for malalignment.

    Hayashi K, Toyoda H, Terai H, Suzuki A, Hoshino M, Tamai K, Ohyama S, Nakamura H

    Journal of neurosurgery. Pediatrics   19 ( 4 )   440 - 447   2017.04（ ISSN:1933-0707 ）

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  • The incidence of nerve root injury by high-speed drill can be reduced by chilled saline irrigation in a rabbit model.

    Tamai K, Suzuki A, Takahashi S, Akhgar J, Rahmani MS, Hayashi K, Ohyama S, Nakamura H

    The bone & joint journal   99-B ( 4 )   554 - 560   2017.04（ ISSN:2049-4394 ）

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  • Anatomical analysis of the relation between human ligamentum flavum and posterior spinal bony prominence.

    Akhgar J, Terai H, Rahmani MS, Tamai K, Suzuki A, Toyoda H, Hoshino M, Ikebuchi M, Ahmadi SA, Hayashi K, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   22 ( 2 )   260 - 265   2017.03（ ISSN:0949-2658 ）

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  • Facet Effusion without Radiographic Instability Has No Effect on the Outcome of Minimally Invasive Decompression Surgery.

    Tamai K, Kato M, Konishi S, Matsumura A, Hayashi K, Nakamura H

    Global spine journal   7 ( 1 )   21 - 27   2017.02（ ISSN:2192-5682 ）

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  • Risk factors of cervical surgery related complications in patients older than 80 years.

    Tamai K, Terai H, Suzuki A, Nakamura H, Yamashita M, Eguchi Y, Imagama S, Ando K, Kobayashi K, Matsumoto M, Ishii K, Hikata T, Seki S, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Endo K, Suzuki H, Nakano A, Watanabe K, Ohya J, Chikuda H, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Sakane M, Yamazaki M, Kaito T, Furuya T, Orita S, Ohtori S

    Spine surgery and related research   1 ( 4 )   179 - 184   2017

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  • Clinical Outcome of Cervical Laminoplasty and Postoperative Radiological Change for Cervical Myelopathy With Degenerative Spondylolisthesis.

    Suzuki A, Tamai K, Terai H, Hoshino M, Toyoda H, Takahashi S, Hayashi K, Ohyama S, Nakamura H

    Spine   41 ( 23 )   1808 - 1812   2016.12（ ISSN:0362-2436 ）

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  • Laminar closure after expansive open-door laminoplasty: fixation methods and cervical alignments impact on the laminar closure and surgical outcomes.

    Tamai K, Suzuki A, Terai H, Toyoda H, Hoshino M, Nakamura H

    The spine journal : official journal of the North American Spine Society   16 ( 9 )   1062 - 9   2016.09（ ISSN:1529-9430 ）

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  • Anatomical Location of the Common Iliac Veins at the Level of the Sacrum: Relationship between Perforation Risk and the Trajectory Angle of the Screw.

    Akhgar J, Terai H, Suhrab Rahmani M, Tamai K, Suzuki A, Toyoda H, Hoshino M, Abdullah Ahmadi S, Hayashi K, Nakamura H

    BioMed research international   2016   1457219   2016（ ISSN:2314-6133 ）

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  • A new corrective technique for adolescent idiopathic scoliosis: convex manipulation using 6.35 mm diameter pure titanium rod followed by concave fixation using 6.35 mm diameter titanium alloy.

    Terai H, Toyoda H, Suzuki A, Dozono S, Yasuda H, Tamai K, Nakamura H

    Scoliosis   10 ( Suppl 2 )   S14   2015（ ISSN:1748-7161 ）

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  • Which is the best schedule of autologous blood storage for preoperative adolescent idiopathic scoliosis patients?

    Tamai K, Terai H, Toyoda H, Suzuki A, Yasuda H, Dozono S, Nakamura H

    Scoliosis   10 ( Suppl 2 )   S11   2015（ ISSN:1748-7161 ）

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  • The novel HECT-type ubiquitin-protein ligase Pub2p shares partially overlapping function with Pub1p in Schizosaccharomyces pombe.

    Tamai KK, Shimoda C

    Journal of cell science   115 ( Pt 9 )   1847 - 57   2002.05（ ISSN:0021-9533 ）

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MISC

Presentations

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Grant-in-Aid for Scientific Research

  • Role of Advanced Glycation End Products (AGEs) in ossification of posterior longitudinal ligament (OPLL)

    Grant-in-Aid for Scientific Research(C)  2027

  • Role of Advanced Glycation End Products (AGEs) in ossification of posterior longitudinal ligament (OPLL)

    Grant-in-Aid for Scientific Research(C)  2026

  • Basic science study of the impact of heated tobacco cessation on the bone healing

    Grant-in-Aid for Scientific Research(C)  2025

  • Role of Advanced Glycation End Products (AGEs) in ossification of posterior longitudinal ligament (OPLL)

    Grant-in-Aid for Scientific Research(C)  2025

  • 慢性頚髄圧迫モデルラットの脊髄症状進行に対する電子タバコエアロゾルの影響

    Grant-in-Aid for Early-Career Scientists  2020.04

  • 電子タバコのエアロゾル吸入が骨癒合に及ぼす影響の検証と禁煙の有効性評価

    2019.04

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Outline of education staff

  • 整形外科一般、脊椎外科一般

Charge of on-campus class subject

  • 整形外科学1

    2025   Weekly class   Undergraduate

  • 運動器

    2025   Weekly class   Undergraduate

International exchange activities

  • カンボジア・プノンペンにおいて、頚椎領域を中心とした手術支援ならびに教育研修セミナー、手術手技ワークショップを実施した。

    Field category :Education

    2026.02

  • North America Spine SocietyのInternational Strategic Growth Committee委員として、タイや台湾、サウジアラビアなどで教育講演を行っている。

    2024.09 - Now

  • SPINE20 Scientific Committee委員長として、G20諸国に対して政策提言作成、シンポジウム企画・運営を主導。

    Field category :Social contributions

    2019 - Now