Updated on 2026/03/09

写真a

 
HASEGAWA ITSUKI
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Lecturer
School of Medicine Department of Medical Science
Title
Lecturer
Affiliation
Institute of Medcine

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Lecturer  2025.04 - Now

  • School of Medicine Department of Medical Science 

    Lecturer  2025.04 - Now

Degree

  • 博士（医学） （ Osaka City University ）

Research Areas

  • Life Science / Neurology

Research Interests

  • Glymphatic system、多光子イメージング

Professional Memberships

  • 日本内科学会

  • 日本微小循環学会

  • 日本神経学会

  • 日本神経治療学会

  • 日本脳循環代謝学会

  • 日本認知症学会

▼display all

Awards

  • 第45回調査研究助成金

    長谷川樹, 武田 景敏, 辻, 浩史, 伊藤 義彰

    2025.12   鈴木謙三記念医科学応用研究財団   MCIおよび初期AD患者の包括的評価と予後予測： 心理検査・画像診断・アンケートを用いた多面的アプローチ

  • 研究助成 高齢者福祉分野

    長谷川樹, 辻 浩史, 本田 茂, 伊藤義彰

    2025.11   三井住友海上福祉財団   眼底検査によるMCI・早期アルツハイマー病の診断と、抗アミロイド抗体療法のリスク評価

Job Career (off-campus)

  • Graduate School of Medicine, Osaka Metropolitan University   Department of Neurology

    2025.04 - Now

  • Graduate School of Medicine, Osaka Metropolitan University   Department of Neurology   Lecturer

    2024.04 - 2025.03

  • Graduate School of Medicine, Osaka Metropolitan University   Department of Neurology   Lecturer

    2022.10 - 2024.03

Papers

  • Anti-Programmed Death-Ligand 1 Antibody-Associated Eosinophilic Granulomatosis with Polyangiitis in Non-Small Cell Lung Cancer: A Case Report

    Sugimoto Akira, Kaneda Hiroyasu, Nozuchi Satoshi, Mino Toshikazu, Hasegawa Itsuki, Mizutani Megumi, Nagamine Hiroaki, Matsumoto Yoshiya, Oka Takako, Tani Yoko, Yamada Kazuhiro, Watanabe Tetsuya, Asai Kazuhisa, Itoh Yoshiaki, Kawaguchi Tomoya

    Internal Medicine   advpub ( 0 )   2026（ ISSN:09182918 ） （ eISSN:13497235 ）

    　More details

    Publishing type：Research paper (scientific journal)  

    <p>Eosinophilic granulomatosis with polyangiitis (EGPA), a subtype of antineutrophil cytoplasmic antibody (ANCA)-related vasculitis, is rarely reported as an immune-related adverse event. We herein present the case of a 61-year-old woman with non-small cell lung cancer treated with durvalumab after definitive chemoradiotherapy. Following durvalumab treatment initiation, she experienced numbness in her hands and feet, and drop foot in her right ankle. She was subsequently diagnosed with peripheral neuropathy, eosinophilia, and myeloperoxidase-ANCA positivity, and had a history of asthma. Consequently, the patient was diagnosed as having EGPA. We report the first case of EGPA caused by durvalumab, an anti-programmed death-ligand 1 (PD-L1) antibody. </p>

    DOI： 10.2169/internalmedicine.6539-25

    PubMed

    CiNii Research

  • A Mild Case of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy With Chronic Onset

    Kenta Aohara, Keitaro Kurooka, Masafumi Nishikawa, Itsuki Hasegawa, Akitoshi Takeda, Hiroshi Tsuji, Yoshiaki Itoh

    Cureus   11 ( 17 )   e83926   2025.12

    　More details

  • A Mild Case of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy With Chronic Onset.

    Aohara K, Kurooka K, Nishikawa M, Hasegawa I, Takeda A, Tsuji H, Itoh Y

    Cureus   17 ( 5 )   e83926   2025.05（ ISSN:2168-8184 ）

    　More details

  • 視野障害と振戦で発症した自己免疫性GFAPアストロサイトパチーの1例

    黒岡 慶太朗, 青原 健太, 西川 真史, 長谷川 樹, 武田 景敏, 木村 暁夫, 下畑 享良, 伊藤 義彰

    臨床神経学   64 ( 10 )   762 - 762   2024.10（ ISSN:0009-918X ）

  • Diffusion Mediates Molecular Transport through the Perivascular Space in the Brain. Reviewed

    Marie Tanaka, Yoko Hirayoshi, Shinobu Minatani, Itsuki Hasegawa, Yoshiaki Itoh

    International journal of molecular sciences   25 ( 5 )   2024.02

    　More details

    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    The perivascular space has been proposed as a clearance pathway for degradation products in the brain, including amyloid β, the accumulation of which may induce Alzheimer's disease. Live images were acquired using a two-photon microscope through a closed cranial window in mice. In topical application experiments, the dynamics of FITC-dextran were evaluated from 30 to 150 min after the application and closure of the window. In continuous injection experiments, image acquisition began before the continuous injection of FITC-dextran. The transport of dextran molecules of different sizes was evaluated. In topical application experiments, circumferential accumulation around the penetrating arteries, veins, and capillaries was observed, even at the beginning of the observation period. No further increases were detected. In continuous injection experiments, a time-dependent increase in the fluorescence intensity was observed around the penetrating arteries and veins. Lower-molecular-weight dextran was transported more rapidly than higher-molecular-weight dextran, especially around the arteries. The largest dextran molecules were not transported significantly during the observation period. The size-dependent transport of dextran observed in the present study strongly suggests that diffusion is the main mechanism mediating substance transport in the perivascular space.

    DOI： 10.3390/ijms25052480

    PubMed

Presentations

Grant-in-Aid for Scientific Research

  • 生体マウスでのライブイメージングを用いた異常蛋白凝集物の脳内伝播機構の解明

    Grant-in-Aid for Early-Career Scientists  2027

  • 生体マウスでのライブイメージングを用いた異常蛋白凝集物の脳内伝播機構の解明

    Grant-in-Aid for Early-Career Scientists  2026

  • 生体マウスでのライブイメージングを用いた異常蛋白凝集物の脳内伝播機構の解明

    Grant-in-Aid for Early-Career Scientists  2025

Charge of off-campus class subject

  • 中枢脱髄疾患(医学部医学科4年次)

    2025.04
    -
    Now
    Institution：Osaka Metropolitan University

  • パーキンソン病と類縁疾患(医学部医学科4年次)

    2024.04
    -
    Now
    Institution：Osaka Metropolitan University

Social Activities　⇒ Link to the list of Social Activities

  • 難病患者における多職種研修会

    Role(s)： Lecturer

    2026.01

  • 大阪市難病相談会

    Role(s)： Lecturer

    Type： Lecture

    大阪市保健所  2023.10