Updated on 2024/04/12

写真a

 
MATSUMOTO Sakiko
 
Organization
Graduate School of Medicine Department of Basic Medical Science Lecturer
School of Medicine Department of Medical Science
Title
Lecturer
Affiliation
Institute of Medicine

Position

  • Graduate School of Medicine Department of Basic Medical Science 

    Lecturer  2023.04 - Now

  • Graduate School of Medicine Department of Basic Medical Science 

    Assistant Professor  2022.04 - 2023.03

  • School of Medicine Department of Medical Science 

    Lecturer  2023.04 - Now

  • School of Medicine Department of Medical Science 

    Assistant Professor  2022.04 - 2023.03

Degree

  • PhD ( Nagoya University )

  • 修士(医科学) ( Osaka City University )

  • 学士(人間科学) ( Osaka University )

Research Areas

  • Life Science / Medical biochemistry

Research Interests

  • 神経科学、神経発生、神経変性、微小管

Research subject summary

  • ・微小管モータータンパク質キネシンおよびダイニンの共通アダプター因子であるNudCの中枢神経系における機能解析
    ・脱リン酸化酵素PP4cの中枢神経系海馬ニューロンにおける基質探索と機能解析

Research Career

  • 微小管モータータンパク質アダプター因子NudCの中枢神経系における機能解析

    大脳皮質層形成、軸索輸送 

    2016.07 - Now 

  • 神経損傷特異的プロテアーゼの神経発生における機能解析

    2011.04 - 2016.06 

Professional Memberships

  • 日本神経化学会

    2024 - Now   Domestic

  • 日本生化学会

    2022 - Now

  • 日本分子生物学会

    2022 - Now

Awards

  • 医学部長賞奨励賞

    2023.03   大阪公立大学医学部  

Job Career (off-campus)

  • 名古屋大学大学院   医学系研究科   研究員(非常勤)

    2015.04 - 2016.06

Papers

  • DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers. Reviewed

    Jin M, Matsumoto S, Ayaki T, Yamakado H, Taguchi T, Togawa N, Konno A, Hirai H, Nakajima H, Komai S, Ishida R, Chiba S, Takahashi R, Takao T, Hirotsune S

    Nature communications   13 ( 1 )   6880   2022.11

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41467-022-34555-4

    PubMed

  • Functional Cooperation of α-Synuclein and Tau Is Essential for Proper Corticogenesis. Reviewed

    Wang S, Fu Y, Miyata T, Matsumoto S, Shinoda T, Itoh K, Harada A, Hirotsune S, Jin M

    The Journal of neuroscience : the official journal of the Society for Neuroscience   42 ( 37 )   7031 - 7046   2022.09( ISSN:0270-6474

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1523/JNEUROSCI.0396-22.2022

    PubMed

  • Correction: Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury. Reviewed

    Kaneko A, Kiryu-Seo S, Matsumoto S, Kiyama H

    Cell death & disease   11 ( 7 )   541   2020.07

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41419-020-2722-7

    PubMed

  • Publisher Correction: Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport. Reviewed

    Toba S, Jin M, Yamada M, Kumamoto K, Matsumoto S, Yasunaga T, Fukunaga Y, Miyazawa A, Fujita S, Itoh K, Fushiki S, Kojima H, Wanibuchi H, Arai Y, Nagai T, Hirotsune S

    Scientific reports   8 ( 1 )   8019   2018.05

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-018-25979-4

    PubMed

  • Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport Reviewed

    Toba Shiori, Jin Mingyue, Yamada Masami, Kumamoto Kanako, Matsumoto Sakiko, Yasunaga Takuo, Fukunaga Yuko, Miyazawa Atsuo, Fujita Sakiko, Itoh Kyoko, Fushiki Shinji, Kojima Hiroaki, Wanibuchi Hideki, Arai Yoshiyuki, Nagai Takeharu, Hirotsune Shinji

    SCIENTIFIC REPORTS   7 ( 1 )   16386   2017.11( ISSN:2045-2322

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-017-15575-3

    PubMed

  • Damage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury. Reviewed

    Kaneko A, Kiryu-Seo S, Matsumoto S, Kiyama H

    Cell death & disease   8 ( 6 )   e2847   2017.06

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/cddis.2017.212

    PubMed

  • Motor Nerve Arborization Requires Proteolytic Domain of Damage-Induced Neuronal Endopeptidase (DINE) during Development. Reviewed

    Matsumoto S, Kiryu-Seo S, Kiyama H

    The Journal of neuroscience : the official journal of the Society for Neuroscience   36 ( 17 )   4744 - 57   2016.04( ISSN:0270-6474

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1523/JNEUROSCI.3811-15.2016

    PubMed

  • N-terminal Cleaved Pancreatitis-associated Protein-III (PAP-III) Serves as a Scaffold for Neurites and Promotes Neurite Outgrowth Reviewed

    Konishi Hiroyuki, Matsumoto Sakiko, Namikawa Kazuhiko, Kiyama Hiroshi

    JOURNAL OF BIOLOGICAL CHEMISTRY   288 ( 15 )   10205 - 10213   2013.04( ISSN:0021-9258

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1074/jbc.M112.395301

    PubMed

  • Expression analysis of the regenerating gene (Reg) family members Reg-III beta and Reg-III gamma in the mouse during development Reviewed

    Matsumoto Sakiko, Konishi Hiroyuki, Maeda Rie, Kiryu-Seo Sumiko, Kiyama Hiroshi

    JOURNAL OF COMPARATIVE NEUROLOGY   520 ( 3 )   479 - 494   2012.02( ISSN:0021-9967

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cne.22705

    PubMed

  • Continuous stress-induced dopamine dysregulation augments PAP-I and PAP-II expression in melanotrophs of the pituitary gland Reviewed

    Konishi Hiroyuki, Ogawa Tokiko, Kawahara Shinichi, Matsumoto Sakiko, Kiyama Hiroshi

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   407 ( 1 )   7 - 12   2011.04( ISSN:0006-291X

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbrc.2011.02.064

    PubMed

  • The pancreatitis-associated protein-III (PAP-III) is polymerized into a fibrillar structure by the cleavage of its N-terminus Reviewed

    Konishi Hiroyuki, Kawahara Shinichi, Matsumoto Sakiko, Maeda Rie, Kiyama Hiroshi

    NEUROSCIENCE RESEARCH   68   E252 - E252   2010( ISSN:0168-0102

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neures.2010.07.1119

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MISC

Presentations

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Grant-in-Aid for Scientific Research

  • 新しく同定したα-シヌクレイン翻訳後修飾によるパーキンソン病発症メカニズムの解明

    Grant-in-Aid for Scientific Research(C)  2024

  • 新しく同定したα-シヌクレイン翻訳後修飾によるパーキンソン病発症メカニズムの解明

    Grant-in-Aid for Scientific Research(C)  2022.04

  • 脱リン酸化酵素PP4c欠損による中枢神経変性のメカニズム解明

    Grant-in-Aid for Early-Career Scientists  2019.04

  • 微小管モータータンパク質制御因子NudCの神経系における機能解析

    Grant-in-Aid for Young Scientists(B)  2017.04

  • 神経再生関連分子の機能解析

    Grant-in-Aid for JSPS Fellows  2012.04

Other subsidies, etc.

  • αシヌクレインのドーパ化修飾によるパーキンソン病中脳黒質選択的な神経 変性メカニズムの解明

    大阪公立大学  2022年度戦略的研究事業若手研究  2022

Outline of education staff

  • 医学部生を対象とした生化学(アミノ酸、ビタミン)講義と、タンパク質の酵素反応に関する実習、および研究室配属学生に対する基礎医学実習

Charge of on-campus class subject

  • 生体物質代謝・生化学コース

    2023     Undergraduate

  • 分子系実習 蛋白質・酵素コース

    2023   Practical Training   Undergraduate

  • 医学研究推進コース3

    2023   Practical Training   Undergraduate

  • 分子系実習 蛋白質・酵素コース

    2022   Practical Training   Undergraduate

  • 修業実習

    2022   Practical Training   Undergraduate

  • 生体物質代謝・生化学コース

    2022     Undergraduate

  • 修業実習

    2021   Practical Training   Undergraduate

  • 分子系実習 蛋白質・酵素コース

    2021   Practical Training   Undergraduate

  • 生体物質代謝・生化学コース

    2021     Undergraduate

  • 分子系実習 蛋白質・酵素コース

    2020     Undergraduate

  • 修業実習

    2020     Undergraduate

  • 生体物質代謝・生化学コース

    2020     Undergraduate

  • 修業実習

    2019     Undergraduate

  • 分子系実習 蛋白質・酵素コース

    2019     Undergraduate

  • 生体物質代謝・生化学コース

    2019     Undergraduate

  • 分子系実習 蛋白質・酵素コース

    2018     Undergraduate

  • 修業実習

    2018     Undergraduate

  • 生体物質代謝・生化学コース

    2018     Undergraduate

  • 修業実習

    2017     Undergraduate

  • 分子系実習 蛋白質・酵素コース

    2017     Undergraduate

  • 生体物質代謝・生化学コース

    2017     Undergraduate

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Charge of off-campus class subject

  • 分子系実習 蛋白質・酵素コース

    Institution:Osaka City University

  • 修業実習

    Institution:Osaka City University

  • 生体物質代謝・生化学コース

    Institution:Osaka City University

  • 解剖学

Faculty development activities

  • 第10回FD-WS  2023

Foreigner acceptance

  • 2018

    International Students :1

  • 2017

    International Students :2

  • 2016

    International Students :1