Updated on 2022/07/13
Graduate School of Medicine Department of Clinical Medical Science
Associate Professor 2022.04 - Now
School of Medicine Department of Medical Science
Associate Professor 2022.04 - Now
医学博士 （ Osaka City University ）
Life Science / Respiratory medicine / Respiratory medicine
respiratory medicine
COPD
bronchial asthma
pulmonary circulation
acute lung injury
Pathophysiology and treatment of respiratory diseases
Respiratory medicine
Airway hyperreactivity, Airway remodeling, Acute lung injury, Airway inflammation Individual
1900.04
THE JANPANESE SOCIETY OF INTERNAL MEDICINE
Domestic
日本肺癌学会
Domestic
日本アレルギー学会
Domestic
日本呼吸器学会
Domestic
理事 日本内科学会近畿地方会
2013.04 - Now
代議員 日本呼吸器学会
2007.04 - Now
(財) 日本アレルギー協会真鍋賞
2016.06
第18回 Pneumo Forum 最優秀賞
2009.11
日本呼吸器学会熊谷賞
2009.06
日本アレルギー学会学術大会賞
2008.06
(財) 日本アレルギー協会学術奨励賞
2005.10
Teacher of the Year (大阪市立大学医学部)
2005.03
第12回 Pneumo Forum 最優秀賞
2003.11
大阪市立大学医学部優秀教育者
2003.10
アストラゼネカ医学研究奨励賞
2003.09
大阪市医学会市長賞
2003.02
日本呼吸器学会奨励賞
2000.03
Osaka City University Doctor's Course Graduated/Completed
1988.04 - 1992.03
Osaka City University Graduated/Completed
1980.04 - 1986.03
Efficacy and safety of ultrasound (US) guided percutaneous needle biopsy for peripheral lung or pleural lesion: comparison with computed tomography (CT) guided needle biopsy Reviewed
Yamamoto N, Watanabe T, Yamada K, Nakai T, Suzumura T, Sakagami K, Yoshimoto N, Sato K, Tanaka H, Mitsuoka S, Asai K, Kimura T, Kanazawa H, Hirata K, Kawaguchi T
JOURNAL OF THORACIC DISEASE 11 ( 3 ) 936 - 943 2019.03（ ISSN:2072-1439 ）
Possible role of airway microvascular permeability on airway obstruction in patients with chronic obstructive pulmonary disease Reviewed
Kyomoto Y, Kanazawa H, Tochino Y, Watanabe T, Asai K, Kawaguchi T
RESPIRATORY MEDICINE 146 137 - 141 2019.01（ ISSN:0954-6111 ）
Evaluation of the severity of small airways obstruction and alveolar destruction in chronic obstructive pulmonary disease. Reviewed
Kawamoto T, Kanazawa H, Tochino Y, Kawaguchi T
Respiratory medicine 141 159 - 164 2018.08（ ISSN:0954-6111 ）
Correlation between disease activity and serum ferritin in clinically amyopathic dermatomyositis with rapidly-progressive interstitial lung disease: a case report. Reviewed
Yamada K, Asai K, Okamoto A, Watanabe T, Kanazawa H, Ohata M, Ohsawa M, Hirata K.
BMC RESEARCH NOTES 11 ( 1 ) 34 - 38 2018.01
Decreased levels of irisin, a skeletal muscle cell-derived myokine, are related to emphysema associated with chronic obstructive pulmonary disease. Reviewed
Sugiyama Y, Asai K, Yamada K, Kureya Y, Ijiri N, Watanabe T, Kanazawa H, Hirata K
International journal of chronic obstructive pulmonary disease 12 765 - 772 2017（ ISSN:1178-2005 ）
Up-regulation of the MicroRNA miR-30c Induced by High Mobility Group Box 1 in A549 Cells Used as an Alveolar Epithelial Model. Reviewed
Nagayasu F, Konishi K, Ijiri N, Asai K, Tochino Y, Kamoi H, Kanazawa H, Hirata K
OSAKA CITY MEDICAL JOURNAL 62 ( 2 ) 121 - 131 2016.12（ ISSN:0030-6096 ）
Down-Regulation of Soluble α-Klotho is Associated with Reduction in Serum Irisin Levels in Chronic Obstructive Pulmonary Disease. Reviewed
Kureya Y, Kanazawa H, Ijiri N, Tochino Y, Watanabe T, Asai K, Hirata K
Lung 194 ( 3 ) 345 - 351 2016.06（ ISSN:0341-2040 ）
Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking. Reviewed
Yamada K, Asai K, Nagayasu F, Sato K, Ijiri N, Yoshii N, Imahashi Y, Watanabe T, Tochino Y, Kanazawa H, Hirata K
BMC pulmonary medicine 16 27 2016.02（ ISSN:1471-2466 ）
Pentraxin-3 as a Biomarker for Febrile Neutropenia in Patients with Lung Cancer. Reviewed
Takeda N, Asai K, Ijiri N, Yamamoto N, Watanabe T, Kamoi H, Kanazawa H, Hirata K
Osaka city medical journal 61 ( 1 ) 43 - 52 2015.06（ ISSN:0030-6096 ）
Irisin, a newly discovered myokine, is a novel biomarker associated with physical activity in patients with chronic obstructive pulmonary disease. Reviewed
Ijiri N, Kanazawa H, Asai K, Watanabe T, Hirata K
Respirology (Carlton, Vic.) 20 ( 4 ) 612 - 617 2015.05（ ISSN:1323-7799 ）
ＰＭＸ－ＤＨＰが著効したステロイド抵抗性の薬剤性肺障害の３症例 Reviewed
玉垣学也、鴨井博、金澤 博、平田 一人
エンドトキシン血症救命治療研究会誌 19 67 - 75 2015
Analysis of the contributing factors to airway hyperresponsiveness by a forced oscillation technique in patients with asthma. Reviewed
Imahashi Y, Kanazawa H, Ijiri N, Yoshii N, Tamagaki G, Asai K, Tochino Y, Hirata K
Osaka city medical journal 60 ( 2 ) 53 - 62 2014.12（ ISSN:0030-6096 ）
Simultaneous assessment of hepatocyte growth factor and vascular endothelial growth factor in epithelial lining fluid from patients with COPD. Reviewed
Kanazawa H, Tochino Y, Asai K, Hirata K
Chest 146 ( 5 ) 1159 - 1165 2014.11（ ISSN:0012-3692 ）
Potential role of pentosidine on susceptibility to small airway closure in elderly and smoking asthma. Reviewed
Kanazawa H, Kyoh S, Tochino Y, Asai K, Hirata K
Respiratory medicine 108 ( 5 ) 709 - 715 2014.05（ ISSN:0954-6111 ）
Epistatic effects of multiple receptor genes on pathophysiology of asthma - its limits and potential for clinical application Reviewed
Yoshikawa T, Kanazawa H, Fujimoto S, Hirata K
MEDICAL SCIENCE MONITOR 20 64 - 71 2014.01（ ISSN:1643-3750 ）
Application of a new parameter in the 6-minute walk test for manifold analysis of exercise capacity in patients with COPD. Reviewed
Ijiri N, Kanazawa H, Yoshikawa T, Hirata K
International journal of chronic obstructive pulmonary disease 9 1235 - 40 2014（ ISSN:1176-9106 ）
エベロリムスによる薬剤性肺障害の１例 Reviewed
武田 倫子, 浅井 一久, 井尻 尚樹, 金澤 博, 内田 潤次, 平田 一人
日本呼吸器学会誌 3 227 - 231 2014
Cellular Signaling Crosstalk Between Multiple Receptors for Investigation of Pathophysiology in Multifactorial Diseases - What is Clinically-Relevant Crosstalk? Reviewed
Yoshikawa T, Kanazawa H
CURRENT MEDICINAL CHEMISTRY 20 ( 9 ) 1091 - 1102 2013.03（ ISSN:0929-8673 ）
Association of airway pentosidine levels with bronchodilator response mediated by salbutamol administration in asthmatic patients. Reviewed
Tamagaki G, Kanazawa H, Hirata K
Pulmonary pharmacology & therapeutics 25 ( 6 ) 478 - 482 2012.12（ ISSN:1094-5539 ）
Integrated effect of EGFR and PAR-1 signaling crosstalk on airway hyperresponsiveness. Reviewed
Yoshikawa T, Kanazawa H
International journal of molecular medicine 30 ( 1 ) 41 - 48 2012.07（ ISSN:1107-3756 ）
Validity of HMGB1 measurement in epithelial lining fluid in patients with COPD. Reviewed
Kanazawa H, Tochino Y, Asai K, Ichimaru Y, Watanabe T, Hirata K
European journal of clinical investigation 42 ( 4 ) 419 - 426 2012.04（ ISSN:0014-2972 ）
Yoshikawa T, Kanazawa H
Allergology international : official journal of the Japanese Society of Allergology 61 ( 1 ) 65 - 73 2012.03（ ISSN:1323-8930 ）
葉書アンケートによるインフルエンザ治療実態調査 Reviewed
栩野 吉弘, 藤岡 雅司, 渡辺 徹也, 田中 秀典, 浅井 一久, 木村 達郎, 鴨井 博, 金澤 博, 新宅 治夫, 平田 一人
日本化学療法学会雑誌 60 541 - 548 2012
成人気管支喘息患者におけるＩＣＳ＋ＬＡＢＡ併用療法からブデソニド/ホルモテロール配合剤 (シムビコートタービュヘイラー) への切り替えによる臨床的検討 Reviewed
今橋 由美子, 玉垣 学也, 小林 大起, 中川 直子, 渡辺 徹也, 浅井 一久, 栩野 吉弘, 鴨井 博, 金澤 博, 平田 一人
呼吸 31 754 - 759 2012
Association of plasma adiponectin levels with cellular hydration state measured using bioelectrical impedance analysis in patients with COPD. Reviewed
Yoshikawa T, Kanazawa H
International journal of chronic obstructive pulmonary disease 7 515 - 521 2012（ ISSN:1176-9106 ）
Measurement of soluble perforin, a marker of CD8+ T lymphocyte activation in epithelial lining fluid. Reviewed
Shiratsuchi N, Asai K, Kanazawa H, Kyoh S, Tochino Y, Kodama T, Hirata K
Respiratory medicine 105 ( 12 ) 1885 - 1890 2011.12（ ISSN:0954-6111 ）
Comparison of alveolar nitric oxide concentrations using two different methods for assessing small airways obstruction in asthma. Reviewed
Kobayashi D, Tochino Y, Kanazawa H, Ichimaru Y, Kyoh S, Asai K, Hirata K
Respirology (Carlton, Vic.) 16 ( 5 ) 862 - 868 2011.07（ ISSN:1323-7799 ）
Association of six-minute walk distance (6MWD) with resting pulmonary function in patients with chronic obstructive pulmonary disease (COPD). Reviewed
Fujimoto H, Asai K, Watanabe T, Kanazawa H, Hirata K
Osaka city medical journal 57 ( 1 ) 21 - 9 2011.06（ ISSN:0030-6096 ）
Increased levels of HMGB-1 and endogenous secretory RAGE in induced sputum from asthmatic patients. Reviewed
Watanabe T, Asai K, Fujimoto H, Tanaka H, Kanazawa H, Hirata K
Respiratory medicine 105 ( 4 ) 519 - 525 2011.04（ ISSN:0954-6111 ）
Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma. Reviewed
Kanazawa H, Tochino Y, Kyoh S, Ichimaru Y, Asai K, Hirata K
The Journal of allergy and clinical immunology 127 ( 4 ) 899 - 904 2011.04（ ISSN:0091-6749 ）
Phenotypic differences between asymptomatic airway hyperresponsiveness and remission of asthma. Reviewed
Yoshikawa T, Kanazawa H
Respiratory medicine 105 ( 1 ) 24 - 30 2011.01（ ISSN:0954-6111 ）
胸腔鏡下胸管結紮術により治癒が得られた特発性乳び胸の1例 Reviewed
白土 直子、浅井 一久、武田 倫子、玉垣 学也、小林 大起、藤本寛樹、渡辺 徹也、姜 成勲、鴨井 博、金澤 博、工藤 新三、花田 庄司、丁 奎光、泉 信博、永野 晃史、西山 典利、平田 一人
日本胸部臨床 70 1070 - 1074 2011
Increased levels of N(epsilon)-(carboxymethyl)lysine in epithelial lining fluid from peripheral airways in patients with chronic obstructive pulmonary disease: a pilot study. Reviewed
Kanazawa H, Kodama T, Asai K, Matsumura S, Hirata K
Clinical science (London, England : 1979) 119 ( 3-4 ) 143 - 149 2010.08（ ISSN:0143-5221 ）
Validity of measurement of two specific biomarkers for the assessment of small airways inflammation in asthma. Reviewed
Kanazawa H, Kyoh S, Asai K, Hirata K
The Journal of asthma : official journal of the Association for the Care of Asthma 47 ( 4 ) 400 - 406 2010.05（ ISSN:0277-0903 ）
Gene polymorphism of epidermal growth factor receptor and airway hyperresponsiveness in young allergic subjects without respiratory symptoms Reviewed
Yoshikawa T, Kanazawa H, Tanaka J, Fujimoto S, Yamamoto T
MEDICAL SCIENCE MONITOR 16 ( 4 ) CR163 - CR171 2010（ ISSN:1643-3750 ）
臨床病理カンファレンス２５ 「慢性閉塞性肺疾患」 Reviewed
金澤 博、鴨井 博、児玉 豊城、姜 成勲、植田 隆子，吉川 貴仁、伊倉 義弘、大澤 政彦、岩田 隆、平田 一人、上田 真喜子
総合臨床 59 1494 - 1502 2010
Increased levels of angiopoietin-2 in induced sputum from smoking asthmatic patients Reviewed
Kanazawa H, Asai K, Tochino Y, Kyoh S, Kodama T, Hirata K
CLINICAL AND EXPERIMENTAL ALLERGY 39 ( 9 ) 1330 - 1337 2009.09（ ISSN:0954-7894 ）
A technological advance comparing epithelial lining fluid from different regions of the lung in smokers. Reviewed
Kodama T, Kanazawa H, Tochino Y, Kyoh S, Asai K, Hirata K
Respiratory medicine 103 ( 1 ) 35 - 40 2009.01（ ISSN:0954-6111 ）
呼吸器感染症に対するLVFX高用量投与の有用性に関する検討 Reviewed
姜 成勲、鴨井 博、金澤 博、平田 一人、栗原 直嗣、三木 文雄、寺田 忠之、高松 健次、仲岡 祐右、玉垣 芳則、松下 晴彦、山田 政司
化学療法の領域 25 116 - 121 2009
活性化トロンビンによる気道リモデリング誘導機序に関する検討 Reviewed
金澤 博、姜 成勲、栩野 吉弘、児玉 豊城、浅井 一久、平田 一人
アレルギー 58 554 - 559 2009
Comparison of N-epsilon-(Carboxymethyl)Lysine levels and percentage of eosinophils in induced sputum for assessment of small airway involvements in asthma. Reviewed
Kyoh S, Kanazawa H, Tochino Y, Kodama T, Asai K, Hirata K
Medical science monitor : international medical journal of experimental and clinical research 14 ( 7 ) CR375 - CR378 2008.07（ ISSN:1234-1010 ）
Association of beta2-adrenoreceptor genotypes with bronchodilatory effect of tiotropium in COPD. Reviewed
Umeda N, Yoshikawa T, Kanazawa H, Hirata K, Fujimoto S
Respirology (Carlton, Vic.) 13 ( 3 ) 346 - 352 2008.05（ ISSN:1323-7799 ）
Angiopoietin-2 as a contributing factor of exercise-induced bronchoconstriction in asthmatic patients receiving inhaled corticosteroid therapy. Reviewed
Kanazawa H, Tochino Y, Asai K
The Journal of allergy and clinical immunology 121 ( 2 ) 390 - 395 2008.02（ ISSN:0091-6749 ）
臨床病理カンファレンス１５ 「特発性間質性肺炎とその類縁疾患」 Reviewed
金澤 博、鴨井 博、児玉 豊城、木村 達郎、浅井 一久、平居 秀和、伊倉 義弘、松岡 利幸、西山 典利、平田 一人、上田 真喜子
総合臨床 58 1855 - 1863 2008
臨床病理カンファレンス７「結核」 Reviewed
工藤 新三、金澤 博、鴨井 博、栩野 吉弘、下内 昭、西田 典史、大澤 政彦、平田 一人、上田 真喜子
総合臨床 57 2965 - 2973 2008
市中肺炎に対するgarenoxacinの有用性の検討 Reviewed
金澤 博、姜 成勲、浅井 一久、栩野 吉弘、光岡 茂樹、鴨井 博、平田 一人
新薬と治療 57 69 - 79 2008
Correlations of health-related quality of life questionnaire results in asthma and allergic rhinitis: Effects of a leukotriene receptor antagonist Reviewed
Ichimaru Y, Kanazawa H, Kamoi H, Kyoh S, Tochino Y, Kodama T, Hirata K
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 36 ( 3 ) 559 - 566 2008（ ISSN:0300-0605 ）
Nepsilon-(carboxymethyl)lysine, a major advanced glycation end product in exhaled breath condensate as a biomarker of small airway involvement in asthma. Reviewed
Tochino Y, Kanazawa H, Ichimaru Y, Asai K, Kyoh S, Hirata K
The Journal of asthma : official journal of the Association for the Care of Asthma 44 ( 10 ) 861 - 866 2007.12（ ISSN:0277-0903 ）
Role of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease Reviewed
Kanazawa H
MEDICAL SCIENCE MONITOR 13 ( 11 ) RA189 - RA195 2007.11（ ISSN:1643-3750 ）
Up-regulation of thrombin activity induced by vascular endothelial growth factor in asthmatic airways. Reviewed
Kanazawa H, Yoshikawa T
Chest 132 ( 4 ) 1169 - 1174 2007.10（ ISSN:0012-3692 ）
Changes in circulating thrombomodulin levels with exercise in patients with chronic obstructive pulmonary disease. Reviewed
Kanazawa H, Asai K, Nomura S
Respirology (Carlton, Vic.) 12 ( 5 ) 670 - 674 2007.09（ ISSN:1323-7799 ）
Azithromycin administration is effective in patients with abnormal bronchoscopic findings Reviewed
Kanazawa H
RESPIROLOGY 12 ( 4 ) 625 - 625 2007.07（ ISSN:1323-7799 ）
Induced sputum analysis in asymptomatic young adults with bronchial hyperresponsiveness to methacholine. Reviewed
Nomura N, Yoshikawa T, Kamoi H, Kanazawa H, Hirata K, Fujimoto S
Respirology (Carlton, Vic.) 12 ( 4 ) 516 - 522 2007.07（ ISSN:1323-7799 ）
Effects of tiotropium or combined therapy with salmeterol on hyperinflation in COPD. Reviewed
Eguchi Y, Tateishi Y, Umeda N, Yoshikawa T, Kamoi H, Kanazawa H, Kudoh S, Hirata K, Fujimoto S
Osaka city medical journal 53 ( 1 ) 25 - 34 2007.06（ ISSN:0030-6096 ）
Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients. Reviewed
Kanazawa H, Nomura S, Asai K
Chest 131 ( 4 ) 1035 - 1041 2007.04（ ISSN:0012-3692 ）
Vascular endothelial growth factor as a non-invasive marker of pulmonary vascular remodeling in patients with bronchitis-type of COPD. Reviewed
Kanazawa H, Asai K, Nomura S
Respiratory research 8 22 2007.03（ ISSN:1465-9921 ）
Efficacy of azithromycin administration in prevention of respiratory tract infection after bronchoscopic biopsy: a randomized, controlled trial. Reviewed
Kanazawa H
Respirology (Carlton, Vic.) 12 ( 1 ) 70 - 75 2007.01（ ISSN:1323-7799 ）
Roles of angiopoietin-1 and -2 on airway microvascular permeability in asthmatic patients.
Chest 131 ( 4 ) 1035 - 1041 2007
Role of vascular endothelial growth factor in pulmonary endothelial cell injury by exercise challenge in asthmatic patients. Reviewed
Kanazawa H, Tochino Y, Ichimaru Y, Kodama T, Kyoh S, Umeda N
The Journal of asthma : official journal of the Association for the Care of Asthma 43 ( 4 ) 267 - 271 2006.05（ ISSN:0277-0903 ）
Alterations in T-lymphocyte subsets in the airways of asthmatic patients with active hepatitis C virus infection. Reviewed
Kanazawa H, Yoshikawa J
Respiration; international review of thoracic diseases 73 ( 3 ) 318 - 323 2006（ ISSN:0025-7931 ）
Potential mechanisms of improvement of airway hyperresponsiveness by inhaled corticosteroid therapy in asthmatic patients. Reviewed
Nomura S, Kanazawa H, Asai K, Nomura N, Hirata K, Yoshikawa J
The Journal of asthma : official journal of the Association for the Care of Asthma 43 ( 2 ) 113 - 117 2006（ ISSN:0277-0903 ）
Effect of beclomethasone dipropionate on basic fibroblast growth factor levels in induced sputum samples from asthmatic patients Reviewed
Kanazawa H, Yoshikawa J
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY 95 ( 6 ) 546 - 550 2005.12（ ISSN:1081-1206 ）
Evaluation of peripheral muscle oxygenation during exercise by spatially resolved spectroscopy in patients with chronic obstructive pulmonary disease. Reviewed
Tateishi Y, Yoshikawa T, Kanazawa H, Fujiwara H, Hirata K, Yoshikawa J, Fujimoto S
Osaka city medical journal 51 ( 2 ) 65 - 72 2005.12（ ISSN:0030-6096 ）
A case-control study of bronchial asthma associated with ulcerative colitis: role of airway microvascular permeability Reviewed
Kanazawa H, Yoshikawa J
CLINICAL AND EXPERIMENTAL ALLERGY 35 ( 11 ) 1432 - 1436 2005.11（ ISSN:0954-7894 ）
Elevated oxidative stress and reciprocal reduction of vascular endothelial growth factor levels with severity of COPD. Reviewed
Kanazawa H, Yoshikawa J
Chest 128 ( 5 ) 3191 - 7 2005.11（ ISSN:0012-3692 ）
Analysis of vascular endothelial growth factor levels in induced sputum samples from patients with cough variant asthma Reviewed
Kanazawa H, Eguchi Y, Nomura N, Yoshikawa J
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY 95 ( 3 ) 266 - 271 2005.09（ ISSN:1081-1206 ）
Role of nitric oxide on airway microvascular permeability in patients with asthma. Reviewed
Tohyama Y, Kanazawa H, Fujiwara H, Hirata K, Fujimoto S, Yoshikawa J
Osaka city medical journal 51 ( 1 ) 1 - 9 2005.06（ ISSN:0030-6096 ）
Effects of pranlukast on vascular endothelial growth factor levels in asthma Reviewed
Kanazawa H
CHEST 127 ( 4 ) 1461 - 1461 2005.04（ ISSN:0012-3692 ）
Relationship between vascular endothelial growth factor and angiopoietin-2 in asthmatics before and after inhaled beclomethasone therapy. Reviewed
Nomura S, Kanazawa H, Hirata K, Iwao H, Yoshikawa J
The Journal of asthma : official journal of the Association for the Care of Asthma 42 ( 2 ) 141 - 6 2005.03（ ISSN:0277-0903 ）
An unique case of primary pulmonary cryptococcosis with extensive chest wall invasion Reviewed
Mitsuoka S, Kanazawa H
THORAX 60 ( 1 ) 86 - 86 2005.01（ ISSN:0040-6376 ）
Relationship between vascular endothelial growth factor and angiopoietin-2 in asthmatics before and after inhaled beclomethasone therapy Reviewed
Nomura S, Kanazawa H, Hirata K, Iwao H, Yoshikawa J
JOURNAL OF ASTHMA 42 ( 2 ) 141 - 146 2005（ ISSN:0277-0903 ）
Elevated oxidative stress and reciprocal reduction of vascular endothelial growth factor levels with severity of chronic obstructive pulmonary disease. Reviewed
Chest 128 ( 5 ) 3191 - 3197 2005
A case-control study of bronchial asthma associated with ulcerative colitis: role of airway microvascular permeability.
Clin Exp Allergy 35 ( 1 ) 1432 - 1436 2005
Acute effects of nifedipine administration in pulmonary haemodynamics and oxygen delivery during exercise in patients with chronic obstructive pulmonary disease: implication of the angiotensin-converting enzyme gene polymorphisms. Reviewed
Kanazawa H, Tateishi Y, Yoshikawa J
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 24 ( 4 ) 224 - 8 2004.07（ ISSN:1475-0961 ）
Accelerated decline in lung function and impaired reversibility with salbutamol in asthmatic patients with chronic hepatitis C virus infection: A 6-year follow-up study Reviewed
Kanazawa H, Yoshikawa J
AMERICAN JOURNAL OF MEDICINE 116 ( 11 ) 749 - 752 2004.06（ ISSN:0002-9343 ）
Role of microvascular permeability on physiologic differences in asthma and eosinophilic bronchitis Reviewed
Kanazawa H, Nomura S, Yoshikawa J
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 169 ( 10 ) 1125 - 1130 2004.05（ ISSN:1073-449X ）
Effects of pranlukast administration on vascular endothelial growth factor levels in asthmatic patients. Reviewed
Kanazawa H, Yoshikawa T, Hirata K, Yoshikawa J
CHEST 125 ( 5 ) 1700 - 5 2004.05（ ISSN:0012-3692 ）
Increased responses to inhaled oxitropium bromide in asthmatic patients with active hepatitis C virus infection. Reviewed
Kanazawa H, Hirata K, Yoshikawa J
CHEST 125 ( 4 ) 1368 - 71 2004.04（ ISSN:0012-3692 ）
Activated Akt expression has significant correlation with EGFR and TGF-alpha expressions in stage I NSCLC. Reviewed
Mukohara T, Kudoh S, Matsuura K, Yamauchi S, Kimura T, Yoshimura N, Kanazawa H, Hirata K, Inoue K, Wanibuchi H, Fukushima S, Yoshikawa J
ANTICANCER RESEARCH 24 ( 1 ) 11 - 7 2004.01（ ISSN:0250-7005 ）
Accelerated decline in lung function and impaired reversibility with salbutamol in asthmatic patients with chronic hepatitis C virus infection: A 6-year follow-up study. Reviewed
Am J Med 116 ( 1 ) 749 - 753 2004
Determinants of the severity of exercise-induced bronchoconstriction in patients with asthma Reviewed
Otani K, Kanazawa H, Fujiwara H, Hirata K, Fujimoto S, Yoshikawa J
JOURNAL OF ASTHMA 41 ( 3 ) 271 - 278 2004（ ISSN:0277-0903 ）
COPD and hepatitis C Reviewed
Kanazawa H
CHEST 124 ( 5 ) 2036 - 2036 2003.11（ ISSN:0012-3692 ）
Influence of oxygen administration on pulmonary haemodynamics and tissue oxygenation during exercise in COPD patients with different ACE genotypes. Reviewed
Kanazawa H, Hirata K, Yoshikawa J
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 23 ( 6 ) 332 - 6 2003.11（ ISSN:1475-0961 ）
Effect of inhaled beclomethasone dipropionate on peroxynitrite inhibitory activity in induced sputum from asthmatic patients. Reviewed
Kanazawa H, Nomura S, Hirata K, Yoshikawa J
CHEST 124 ( 5 ) 1755 - 61 2003.11（ ISSN:0012-3692 ）
Imbalance between vascular endothelial growth factor and endostatin in emphysema Reviewed
Kanazawa H, Hirata K, Yoshikawa J
EUROPEAN RESPIRATORY JOURNAL 22 ( 4 ) 609 - 612 2003.10（ ISSN:0903-1936 ）
Evaluation of oxygen uptake kinetics and oxygen kinetics of peripheral skeletal muscle during recovery from exercise in patients with chronic obstructive pulmonary disease. Reviewed
Okamoto T, Kanazawa H, Hirata K, Yoshikawa J
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 23 ( 5 ) 257 - 62 2003.09（ ISSN:1475-0961 ）
Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-small-cell lung cancer (NSCLC) Reviewed
Mukohara T, Kudoh S, Yamauchi S, Kimura T, Yoshimura N, Kanazawa H, Hirata K, Wanibuchi H, Fukushima S, Inoue K, Yoshikawa J
LUNG CANCER 41 ( 2 ) 123 - 130 2003.08（ ISSN:0169-5002 ）
Effects of captopril administration on pulmonary haemodynamics and tissue oxygenation during exercise in ACE gene subtypes in patients with COPD: a preliminary study Reviewed
Kanazawa H, Hirata K, Yoshikawa J
THORAX 58 ( 7 ) 629 - 631 2003.07（ ISSN:0040-6376 ）
Increased levels of vascular endothelial growth factor in induced sputum in asthmatic patients Reviewed
Asai K, Kanazawa H, Kamoi H, Shiraishi S, Hirata K, Yoshikawa J
CLINICAL AND EXPERIMENTAL ALLERGY 33 ( 5 ) 595 - 599 2003.05（ ISSN:0954-7894 ）
Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease Reviewed
Kanazawa H, Asai K, Hirata K, Yoshikawa J
AMERICAN JOURNAL OF MEDICINE 114 ( 5 ) 354 - 358 2003.04（ ISSN:0002-9343 ）
Accelerated decline of lung function in COPD patients with chronic hepatitis C virus infection - A preliminary study based on small numbers of patients Reviewed
Kanazawa H, Hirata K, Yoshikawa J
CHEST 123 ( 2 ) 596 - 599 2003.02（ ISSN:0012-3692 ）
Interferon therapy induces the improvement of lung function by inhaled corticosteroid therapy in asthmatic patients with chronic hepatitis C virus infection: a preliminary study. Reviewed
Kanazawa H, Mamoto T, Hirata K, Yoshikawa J
CHEST 123 ( 2 ) 600 - 603 2003.02（ ISSN:0012-3692 ）
Imbalance between levels of nitrogen oxides and peroxynitrite inhibitory activity in chronic obstructive pulmonary disease Reviewed
Kanazawa H, Shiraishi S, Hirata K, Yoshikawa J
THORAX 58 ( 2 ) 106 - 109 2003.02（ ISSN:0040-6376 ）
Imbalance between vascular endothelial growth factor and endostatin in emphysema Reviewed
Eur Respir J 22 ( 1 ) 609 - 612 2003
Possible effects of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease. Reviewed
Am J Med 114 354 - 358 2003
Imbalance between vascular endothelial growth factor and endostatin levels in induced sputum from asthmatic subjects Reviewed
Asai K, Kanazawa H, Otani K, Shiraishi S, Hirata K, Yoshikawa J
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 110 ( 4 ) 571 - 575 2002.10（ ISSN:0091-6749 ）
Involvement of vascular endothelial growth factor in exercise induced bronchoconstriction in asthmatic patients Reviewed
Kanazawa H, Hirata K, Yoshikawa J
THORAX 57 ( 10 ) 885 - 888 2002.10（ ISSN:0040-6376 ）
Transient increase in endothelin-1 levels in the pulmonary circulation during exercise while breathing of oxygen in patients with chronic obstructive pulmonary disease. Reviewed
Kanazawa H, Hirata K, Yoshikawa J
INTERNAL MEDICINE 41 ( 7 ) 522 - 5 2002.07（ ISSN:0918-2918 ）
Vascular involvement in exercise-induced airway narrowing in patients with bronchial asthma. Reviewed
Kanazawa H, Asai K, Hirata K, Yoshikawa J
CHEST 122 ( 1 ) 166 - 70 2002.07（ ISSN:0012-3692 ）
Decreased peroxynitrite inhibitory activity in induced sputum in patients with bronchial asthma Reviewed
Kanazawa H, Shiraishi S, Hirata K, Yoshikawa J
THORAX 57 ( 6 ) 509 - 512 2002.06（ ISSN:0040-6376 ）
Association between the angiotensin-converting enzyme gene polymorphisms and tissue oxygenation during exercise in patients with COPD. Reviewed
Kanazawa H, Otsuka T, Hirata K, Yoshikawa J
CHEST 121 ( 3 ) 697 - 701 2002.03（ ISSN:0012-3692 ）
Nitrogen oxides reduce albuterol-induced bronchodilation in patients with bronchial asthma Reviewed
Kanazawa H, Hirata K, Yoshikawa J
RESPIRATION 69 ( 6 ) 490 - 495 2002（ ISSN:0025-7931 ）
両側に気胸を反復し、NSIP Group 2と考えられた上葉優位な間質性肺炎の一例 Reviewed
鴨井 博、岡本 隆司、吉村 成央、白石 訓、浅井 一久、金澤 博、工藤 新三、平田 一人、吉川 純一
日本呼吸器学会雑誌 40 936 - 940 2002
Association between the angiotensin converting enzyme gene polymorphisms and tissue oxygenation during exercise in patients with chronic obstructive pulmonary disease. Reviewed
Chest 121 697 - 701 2001
Role of endogenous nitric oxide in exercise-induced airway narrowing in patients with bronchial asthma Reviewed
Kanazawa H, Hirata K, Yoshikawa J
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 106 ( 6 ) 1081 - 1087 2000.12（ ISSN:0091-6749 ）
Deletion polymorphisms in the angiotensin converting enzyme gene are associated with pulmonary hypertension evoked by exercise challenge in patients with chronic obstructive pulmonary disease Reviewed
Kanazawa H, Okamoto T, Hirata K, Yoshikawa J
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 162 ( 4 ) 1235 - 1238 2000.10（ ISSN:1073-449X ）
Possible mechanism of bronchoprotection by SIN-1 in anaesthetized guinea pigs: roles of nitric oxide and peroxynitrite Reviewed
Kanazawa H, Hirata K, Yoshikawa J
CLINICAL AND EXPERIMENTAL ALLERGY 30 ( 3 ) 445 - 450 2000.03（ ISSN:0954-7894 ）
Administration of SIN-1 induces guinea pig airway hyperresponsiveness through inactivation of airway neutral endopeptidase Reviewed
Kanazawa H, Hirata K, Yoshikawa J
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 120 ( 4 ) 317 - 322 1999.12（ ISSN:1018-2438 ）
Inhibition of bronchoprotective effects of beta(2)-adrenoceptor agonists by peroxynitrite in guinea pig airways Reviewed
Kanazawa H, Shiraishi S, Okamoto T, Hirata K, Yoshikawa J
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 159 ( 4 ) 1272 - 1276 1999.04（ ISSN:1073-449X ）
Guinea pig airway hyperresponsiveness induced by blockade of the angiotensin II type 1 receptor - Role for endogenous nitric oxide Reviewed
Kanazawa H, Hirata K, Yoshikawa J
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 159 ( 1 ) 165 - 168 1999.01（ ISSN:1073-449X ）
Plasma endothelin-1 level in chronic obstructive pulmonary disease: Relationship with natriuretic peptide Reviewed
Fujii T, Otsuka T, Tanaka S, Kanazawa H, Hirata K, Kohno M, Kurihara N, Yoshikawa J
RESPIRATION 66 ( 3 ) 212 - 219 1999（ ISSN:0025-7931 ）
Subthreshold concentration of endothelin-1-enhanced, capsaicin-induced bronchoconstriction in anaesthetized guinea-pigs Reviewed
Kanazawa H, Fujiwara H, Hirata K, Yoshikawa J
EUROPEAN RESPIRATORY JOURNAL 12 ( 6 ) 1307 - 1312 1998.12（ ISSN:0903-1936 ）
Increased production of endogenous nitric oxide in patients with bronchial asthma and chronic obstructive pulmonary disease Reviewed
Kanazawa H, Shoji S, Yoshikawa T, Hirata K, Yoshikawa J
CLINICAL AND EXPERIMENTAL ALLERGY 28 ( 10 ) 1244 - 1250 1998.10（ ISSN:0954-7894 ）
Severity of exercise-induced bronchoconstriction is related to airway eosinophilic inflammation in patients with asthma Reviewed
Yoshikawa T, Shoji S, Fujii T, Kanazawa H, Kudoh S, Hirata K, Yoshikawa J
EUROPEAN RESPIRATORY JOURNAL 12 ( 4 ) 879 - 884 1998.10（ ISSN:0903-1936 ）
CYFRA 21-1, a cytokeratin subunit 19 fragment, in bronchoalveolar lavage fluid from patients with interstitial lung disease Reviewed
Kanazawa H, Yoshikawa T, Yamada M, Shoji S, Fujii T, Kudoh S, Hirata K, Yoshikawa J
CLINICAL SCIENCE 94 ( 5 ) 531 - 535 1998.05（ ISSN:0143-5221 ）
Clinical implication of protein levels of IL-5 in induced sputum in asthmatic patients Reviewed
Shoji S, Kanazawa H, Hirata K, Kurihara N, Yoshikawa J
JOURNAL OF ASTHMA 35 ( 3 ) 243 - 249 1998（ ISSN:0277-0903 ）
PAMP is a novel inhibitor of the tachykinin release in the airway of guinea pigs Reviewed
Kanazawa H, Kamoi H, Kawaguchi T, Shoji S, Fujii T, Kudoh S, Hirata K, Yoshikawa J
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 272 ( 6 ) L1066 - L1069 1997.06（ ISSN:1040-0605 ）
Increased levels of nitric oxide derivatives in induced sputum in patients with asthma Reviewed
Kanazawa H, Shoji S, Yamada M, Fujii T, Kawaguchi T, Kudoh S, Hirata K, Yoshikawa J
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 99 ( 5 ) 624 - 629 1997.05（ ISSN:0091-6749 ）
Synergistic effect of nitric oxide and vasoactive intestinal peptide on bronchoprotection against histamine in anesthetized guinea pigs Reviewed
Kanazawa H, Kawaguchi T, Shoji S, Fujii T, Kudoh S, Hirata K, Kurihara N, Yoshikawa J
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 155 ( 2 ) 747 - 750 1997.02（ ISSN:1073-449X ）
Adenosine modulates endothelin-induced bronchoconstriction in guinea pig airway Reviewed
Kanazawa H, Fujiwara H, Shoji S, Fujii T, Kudoh S, Hirata K, Kurihara N, Yoshikawa J
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 112 ( 1 ) 83 - 87 1997.01（ ISSN:1018-2438 ）
慢性閉塞性肺疾患患者における運動誘発性低酸素血症と長期予後の関係 Reviewed
藤井 達夫、栗原 直嗣、大塚 敏広、田中 繁宏、金澤 博、工藤 新三、平田 一人、藤本 繁夫、吉川 純一
日本胸部疾患学会雑誌 35 934 - 941 1997
肺癌化学療法における骨髄抑制に対するOK-432とG-CSFの併用効果の検討 Reviewed
大塚 敏広、工藤 新三、沖塩 協一、山田 政司、川口 俊、少路 誠一、藤井 達夫、金澤 博、平田 一人、吉川 純一、栗原 直嗣
Biotherapy 11 851 - 855 1997
Potentiation of the bronchoprotective effects of vasoactive intestinal peptide, isoprenaline, and theophylline against histamine challenge in anaesthetised guinea pigs by adrenomedullin Reviewed
Kanazawa H, Kawaguchi T, Fujii T, Shoji S, Hirata K, Kudoh S, Kurihara N, Yoshikawa J
THORAX 51 ( 12 ) 1199 - 1202 1996.12（ ISSN:0040-6376 ）
An accelerated increase of plasma adrenomedullin in acute asthma Reviewed
Kohno M, Hanehira T, Hirata K, Kawaguchi T, Okishio K, Kano H, Kanazawa H, Yoshikawa J
METABOLISM-CLINICAL AND EXPERIMENTAL 45 ( 11 ) 1323 - 1325 1996.11（ ISSN:0026-0495 ）
Role of endogenous nitric oxide in airflow obstruction in smokers Reviewed
Kanazawa H, Shoji S, Hirata K, Kurihara N, Yoshikawa J
CHEST 110 ( 4 ) 927 - 929 1996.10（ ISSN:0012-3692 ）
Calcitonin gene-related peptide antagonizes the protective effect of adrenomedullin on histamine-induced bronchoconstriction Reviewed
Kanazawa H, Kawaguchi T, Kamoi H, Fujii T, Kudoh S, Hirata K, Kurihara N, Yoshikawa J
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 23 ( 6-7 ) 472 - 475 1996（ ISSN:0305-1870 ）
亜急性知覚神経障害で発症したanti-Hu antibody 陽性小細胞肺癌の１例 Reviewed
沖塩 協一、工藤 新三、勝元 栄一、大塚 敏広、少路 誠一、藤井 達夫、金澤 博、平田 一人、栗原 直嗣、吉川 純一
日本胸部疾患学会雑誌 34 816 - 821 1996
多発性気管支静脈瘤の１例 Reviewed
大塚 敏広、沖塩 協一、川口 俊、藤井 達夫、少路 誠一、金澤 博、工藤 新三、平田 一人、栗原 直嗣
日本胸部疾患学会雑誌 34 327 - 330 1996
COPD患者の運動訓練とdetrainingの運動能への影響 Reviewed
大塚 敏広、栗原 直嗣、藤井 達夫、金澤 博、工藤 新三、平田 一人、藤本 繁夫、吉川 純一
厚生省特定疾患呼吸不全調査研究班 7 156 - 159 1996
Clinical significance of serum concentration of interleukin-8 in patients with bronchial asthma or chronic pulmonary emphysema Reviewed
Kanazawa H, Kurihara N, Otsuka T, Fujii T, Tanaka S, Kudoh S, Hirata K, Takeda T
RESPIRATION 63 ( 4 ) 236 - 240 1996（ ISSN:0025-7931 ）
COMPARISON OF BRONCHODILATOR RESPONSES TO ADRENOMEDULLIN AND PROADRENOMEDULLIN N-TERMINAL-20-PEPTIDE Reviewed
Kanazawa H, Kawaguchi T, Fujii T, Kudoh S, Hirata K, Kurihara N, Takeda T
LIFE SCIENCES 57 ( 16 ) PL241 - PL245 1995.09（ ISSN:0024-3205 ）
ADRENOMEDULLIN INHIBITS THE SECRETION OF CYTOKINE-INDUCED NEUTROPHIL CHEMOATTRACTANT, A MEMBER OF THE INTERLEUKIN-8 FAMILY, FROM RAT ALVEOLAR MACROPHAGES Reviewed
Kamoi H, Kanazawa H, Hirata K, Kurihara N, Yano Y, Otani S
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 211 ( 3 ) 1031 - 1035 1995.06（ ISSN:0006-291X ）
ANGIOTENSIN-II STIMULATES PEPTIDE LEUKOTRIENE PRODUCTION BY GUINEA-PIG AIRWAY VIA THE AT(1) RECEPTOR PATHWAY Reviewed
Kanazawa H, Kurihara N, Hirata K, Kudoh S, Fujii T, Tanaka S, Takeda T
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 52 ( 4 ) 241 - 244 1995.04（ ISSN:0952-3278 ）
ANGIOTENSIN-II STIMULATES PRODUCTION OF NITRIC-OXIDE IN GUINEA-PIG AIRWAYS VIA AT(1) RECEPTOR ACTIVATION Reviewed
Kanazawa H, Kurihara N, Hirata K, Fujiwara H, Takeda T
LIFE SCIENCES 56 ( 17 ) 1427 - 1431 1995.03（ ISSN:0024-3205 ）
THROMBOMODULIN IN EXERCISE-INDUCED ASTHMA Reviewed
Kanazawa H, Kurihara N, Hirata K, Kamimori T, Takeda T
INTERNAL MEDICINE 34 ( 3 ) 158 - 162 1995.03（ ISSN:0918-2918 ）
慢性肺疾患患者のステロイド性骨粗鬆症に対する活性型ビタミンD3(1α-OH-D3)の使用経験 Reviewed
栗原 直嗣、平田 一人、藤本 繁夫、浜田 朝夫、後藤 武、藤原 寛、金澤 博、小松 孝、黒田 富士子、藤原 聖之、玉垣 芳則
医学と薬学 34 101 - 107 1995
ADRENOMEDULLIN, A NEWLY DISCOVERED HYPOTENSIVE PEPTIDE, IS A POTENT BRONCHODILATOR Reviewed
Kanazawa H, Kurihara N, Hirata K, Kudoh S, Kawaguchi T, Takeda T
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205 ( 1 ) 251 - 254 1994.11（ ISSN:0006-291X ）
ATLウイルスキャリアーに発症したAngiocentric Immunoproliferative Lesionsの１例 Reviewed
藤原 寛、栗原 直嗣、太田 勝康、平田 一人、松下 晴彦、金澤 博、武田 忠直
日本胸部疾患学会雑誌 32 469 - 475 1994
タザノラストが有効であったC型慢性肝炎合併の気管支喘息症例 Reviewed
金澤 博、栗原 直嗣、平田 一人、工藤 新三、田中 繁宏、藤井 達夫、少路 誠一、川口 俊、大塚 敏広、沖塩 協一、武田 忠直
医薬の門 34 431 - 433 1994
EFFECT OF NEUROPEPTIDE-Y ON HUMAN BRONCHUS AND ITS MODULATION OF NEUTRAL ENDOPEPTIDASE Reviewed
Fujiwara H, Kurihara N, Hirata K, Ohta K, Kanazawa H, Takeda T
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 92 ( 1 ) 89 - 94 1993.07（ ISSN:0091-6749 ）
EFFECT OF A NEW LEUKOTRIENE RECEPTOR ANTAGONIST, ONO-1078, ON HUMAN BRONCHIAL SMOOTH-MUSCLE INVITRO Reviewed
Fujiwara H, Kurihara N, Ohta K, Hirata K, Matsushita H, Kanazawa H, Takeda T
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 48 ( 3 ) 241 - 246 1993.03（ ISSN:0952-3278 ）
両肺野にびまん性一部著明融合像を示す浸潤様影と両側肺門リンパ節腫脹（BHL）を認めたサルコイドーシスの一症例 Reviewed
鴨井 博、栗原 直嗣、平田 一人、川口 俊、紙森 隆雄、田中 繁宏、若山 公作、金澤 博、藤原 寛、藤井 達夫、藤本 繁夫、武田 忠直
呼吸 12 918 - 924 1993
LOW CONCENTRATION ENDOTHELIN-1 ENHANCED HISTAMINE-MEDIATED BRONCHIAL CONTRACTIONS OF GUINEA-PIGS INVIVO Reviewed
Kanazawa H, Kurihara N, Hirata K, Fujiwara H, Matushita H, Takeda T
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 187 ( 2 ) 717 - 721 1992.09（ ISSN:0006-291X ）
THE ROLE OF FREE-RADICALS AND NEUTROPHIL ELASTASE IN DEVELOPMENT OF PULMONARY-EMPHYSEMA Reviewed
Kanazawa H, Kurihara N, Hirata K, Fujimoto S, Takeda T
INTERNAL MEDICINE 31 ( 7 ) 857 - 860 1992.07（ ISSN:0918-2918 ）
慢性閉塞性肺疾患患者における運動負荷時の呼吸筋機能と呼吸困難への酸素投与の効果 Reviewed
松下 晴彦、栗原 直嗣、若山 公作、藤本 繁夫、金澤 博、藤原 寛、足立 規子、平田 一人、太田 勝康、武田 忠直
日本胸部疾患学会雑誌 30 1116 - 1124 1992
肺気腫患者における抗コリン剤 (オキシトロピウム) とβ２刺激剤 (フェノテロール）の順序を変えた単回併用吸入による気管支拡張効果の比較 Reviewed
栗原 直嗣、藤本 繁夫、平田 一人、若山 公作、川口 知哉、紙森 隆雄、金澤 博、足立 規子、松下 晴彦、太田 勝康、武田 忠直、背古 和人
呼吸 11 1600 - 1607 1992
THE ROLE OF FREE-RADICALS IN AIRWAY-OBSTRUCTION IN ASTHMATIC-PATIENTS Reviewed
Kanazawa H, Kurihara N, Hirata K, Takeda T
CHEST 100 ( 5 ) 1319 - 1322 1991.11（ ISSN:0012-3692 ）
慢性肺疾患患者に対する肺炎球菌ワクチン接種の抗原性と臨床効果の検討 Reviewed
藤本 繁夫、栗原 直嗣、平田 一人、太田 勝康、松下 晴彦、藤原 寛、金澤 博、足立 規子、若山 公作、武田 忠直
新薬と臨床 40 72 - 78 1991
成人気管支喘息におけるイブジラストの臨床効果 Reviewed
平田 一人、栗原 直嗣、藤本 繁夫、引石 文夫、太田 勝康、松下 晴彦、藤原 寛、金澤 博、若山 公作、武田 忠直
アレルギーの臨床 11 63 - 72 1991
1. O-Chlorobenzylidene malononitrile (CS) 暴露症例の肺胞気道系変化 Reviewed
平田 一人、栗原 直嗣、引石 文夫、金澤 博、藤原 寛、平賀 通、松下 晴彦、太田 勝康、藤本 繁夫、武田 忠直
呼吸 9 878 - 884 1990
新呼吸器専門医テキスト
金澤 博 他（ Role： Joint author）
南江堂 2015
COPDにおける肺血管リモデリング Invited Reviewed
金澤 博
心臓 45 407 - 412 2013
Cellular signaling crosstalk between multiple receptors for investigation of pathophysiology in multifactorial diseases - What is clinically-relevant crosstalk? Reviewed
Yoshikawa T, Kanazawa H
Curr Med Chem 20 1091 - 1102 2013
bFGFの気道リモデリング誘導機序 Invited Reviewed
金澤 博
呼吸 29 548 - 552 2011
気管支喘息におけるHMGB1の病態生理学的関与 Invited Reviewed
金澤 博
International Review of Asthma & COPD 13 3 - 28 2011
医学と医療の最前線「気道リモデリングと血管リモデリングのクロストーク」 Invited Reviewed
金澤 博、平田 一人
日本内科学会雑誌 10 3361 - 3367 2011
気道リモデリングと血管リモデリングのクロストーク Invited Reviewed
金澤 博
アレルギーの臨床 31 597 - 601 2011
Functional crosstalk between β2-adrenoreceptor and muscarinic acetylcholine receptor: implications for bronchodilatory responses in patients with asthma and COPD Reviewed
Yoshikawa T, Kanazawa H
Curr Pharmacogenomics & Personalized Med 6 302 - 319 2008
高齢者喘息への研究アプローチ (2): 生理活性物質を中心に Invited Reviewed
金澤 博、平田 一人
アレルギーの臨床 27 45 - 51 2007
ブデソニド吸入製剤の薬剤特性を生かした気道リモデリングの治療戦略 Invited Reviewed
金澤 博、平田 一人
アレルギー・免疫 14 110 - 116 2007
特集：気道構成細胞と喘息. 血管内皮細胞 Invited Reviewed
金澤 博
喘息 20 49 - 54 2007
VEGFとロイコトリエン Invited Reviewed
金澤 博
臨床免疫・アレルギー科 47 498 - 503 2007
Role of vascular endothelial growth factor in the pathogenesis of chronic obstructive pulmonary disease Reviewed
Kanazawa H
Med Sci Monit 13, RA189-195. 13 189 - 195 2007
Microvascular theory of exercise-induced bronchoconstriction in asthma: Potential implication of vascular endothelial growth factor Reviewed
Kanazawa H
Med Sci Monit 13 189 - 195 2007
VEGF, Angiopioietin-1 and -2 in bronchial asthma: New molecular targets in airway angiogenesis and microvascular remodeling.
Recent Patents Inflammation& Allergy Drug Discovery 1 ( 1 ) 1 - 8 2007
気道リモデリングにおける血管新生の分子機序 Invited Reviewed
金澤 博
アレルギー・免疫. 13, 48-53. 13 48 - 53 2006
Anticholinergic agents in asthma: chronic bronchodilator therapy, relief of acute severe asthma, reduction of chronic viral inflammation and prevention of airway remodeling.
Curr Opin Pulm Med 12 ( 1 ) 60 - 67 2006
The relationship between HCV and pulmonary disorders: potential mechanisms of interaction.
Expert Rev Clin Immunol 2 ( 5 ) 801 - 810 2006
気道微小循環を基盤とする気管支喘息の新規病態生理の確立 Invited Reviewed
金澤 博
アレルギア 34 54 - 56 2005
喫煙とACE遺伝子多型 Invited Reviewed
金澤 博
呼吸器科 6 549 - 554 2004
気道微小血管透過性と吸入ステロイド Invited Reviewed
金澤 博
Pharma Medica. 22, 21-26. 22 21 - 26 2004
高齢者肺炎におけるガチフロキサシンの有用性 Invited Reviewed
金澤 博
Progress in Medicine 23 160 - 161 2003
COPDにおける肺高血圧とACE遺伝子多型 Invited Reviewed
金澤 博、平田 一人
分子呼吸器病 6 33 - 35 2002
アレルギー性鼻炎合併喘息 Invited Reviewed
金澤 博、平田 一人
アレルギー科 13 336 - 340 2002
Clinical aspects of delayed hypersensitivity in lungs: Pathophysiology of hypersensitivity disorders in clinics.
Microsc. Res. Tech. 53 ( 4 ) 307 - 312 2001
アドレノメデュリン Invited Reviewed
金澤 博
Pharma Medica 17 57 - 63 1999
呼吸器疾患におけるアドレノメデュリンの意義 Invited Reviewed
金澤 博
医学のあゆみ 184 79 - 81 1998
アドレノメデュリンと気道反応 Invited Reviewed
金澤 博、平田 一人、吉川 純一
現代医療 28 93 - 97 1996
慢性閉塞性肺疾患の臨床 Invited Reviewed
栗原 直嗣、平田 一人、金澤 博
日本医事新報 3729 17 - 22 1995
肺胞マクロファージと気道炎症 Reviewed
平田 一人、金澤 博、栗原 直嗣、武田 忠直
呼吸 11 1643 - 1649 1992
咳・息切れで悩む患者の診断と治療 Invited Domestic conference
金澤 博
東成区医師会学術講演会 2020.12
LABA/LAMA/ICS製剤の位置づけ Invited Domestic conference
金澤 博
赤穂市医師会学術講演会 2020.11
NEAT1 helps to promote IL-8 mRNA expressions in BEAS-2B stimulated by CSE Domestic conference
2020.09
Astaxanthin suppresses cigarette smoke-induced emphysema through Nrf2 activation in mice Domestic conference
2020.09
COPD診療に取り組むメリットは？ Invited Domestic conference
金澤 博
布施医師会学術講演会 2020.09
気道の老化反応から見た喘息とCOPDのオーバーラップ(ACO)の病態 Invited Domestic conference
金澤 博
第58回日本呼吸器学会学術講演会 2018.04
サルコペニアとマイオカイン Domestic conference
浅井 一久、井尻 尚樹、金澤 博、平田 一人
第56回日本呼吸器学会総会 2016
COPD患者における可溶性α-klothoの肺及び骨格筋に及ぼす生理作用 Domestic conference
呉家 由子、金澤 博
第56回日本呼吸器学会総会 2016
喘息・COPDにおける気道系・血管系のリモデリングの相違点と類似点 Domestic conference
浅井 一久, 金澤 博, 平田 一人
第55回日本呼吸器学会学術講演会 2015
気管支喘息患者における運動耐容能に関する検討 Domestic conference
佐藤 佳奈子, 金澤 博
第64回日本アレルギー学会学術大会 2015
呼吸器疾患における栄養管理 栄養障害の病態と予後 COPDとやせ Domestic conference
浅井 一久, 栩野 吉弘, 鴨井 博, 金澤 博, 平田 一人
第24回日本呼吸ケア・リハビリテーション学会学術集会 2014
Role of HMGB1 in the pathogenesis of COPD Invited International conference
Kanazawa H
116th Annual meeting of KATRD 2013
喘息病態の修飾因子・難治化因子；喫煙 Domestic conference
浅井 一久, 金澤 博, 平田 一人
第61回日本アレルギー学会秋季学術大会 2011
Mechanisms of corticosteroid resistance in smoking asthmatic patients - potential role of angiopoietin-2 Domestic conference
金澤 博
第50回日本呼吸器学会総会 2010
アレルギー疾患に用いられる薬物療法の実際 Domestic conference
金澤 博
第22回日本アレルギー学会春季臨床大会 2010
気道微小循環系を基盤とする気管支喘息の新規病態生理の確立 Invited Domestic conference
金澤 博
第49回日本呼吸器学会総会 2009
誘発喀痰を用いた気道炎症の評価とモニタリング Domestic conference
金澤 博
第20回日本アレルギー学会春季臨床大会 2008
VEGFとロイコトリエン Domestic conference
金澤 博
第18回日本アレルギー学会春季臨床大会 2006
気道リモデリングと血管新生 Domestic conference
金澤 博
第18回日本アレルギー学会春季臨床大会 2006
The involvement of vascular endothelial growth factor in airway vascular remodeling Invited Domestic conference
金澤 博
第55回日本アレルギー学会秋季学術大会 2005
慢性閉塞性肺疾患における運動と肺循環動態 - ACE遺伝子多型解析の臨床的意義 Domestic conference
金澤 博
第12回日本呼吸器学会 2005
Increased levels of vascular endothelial growth factor in induced sputum in asthmatic patients International conference
Kanazawa H
12th European Respiratory Society Annual Congress 2002
特殊な喘息の病態; アレルギー性鼻炎合併喘息 Domestic conference
金澤 博
第13回日本アレルギー学会春季臨床大会 2001
気管支喘息における気道内NO過剰産生の病態生理学的意義 Invited Domestic conference
金澤 博
第40回 日本呼吸器学会総会 2000
PAMP is a novel inhibitor of the tachykinin release in the airways of guinea pigs Invited International conference
Kanazawa H
1st International Symposium on Adrenomedullin and PAMP 1998
Priming of neutrophils in asthmatics International conference
Kanazawa H
13th World Allergy Congress of Asthmology 1990
末梢気道の血管透過性から見たCOPDの増悪発症機序の解明と新規治療戦略の確立
Grant-in-Aid for Scientific Research(C) 2017.04
Elucidation of the pathophysiology of intractable asthma from the view-point of aging of airway tissues and establishment of new treatment strategy
Grant-in-Aid for Scientific Research(C) 2014.04
Establishment of the comprehensive medical treatment strategy of chronic obstructive pulmonary disease based on the concept of cardio-pulmonary connection
Grant-in-Aid for Scientific Research(C) 2011
Elucidation of molecular mechanisms of angiogenesis mediated by angiopoietins and its application for asthma therapy
Grant-in-Aid for Scientific Research(C) 2008
ESTABLISHMENT OF PATHOPHYSIOLOGY OF ASTHMA BASED ON AIRWAY MICROCIRCULATION AND ITS APPLICATION FOR NEW THERAPY STRATEGY
Grant-in-Aid for Scientific Research(C) 2005
EVALUATION OF GENETIC FACTORS FOR THE DEVELOPMENT OF SECONDARY PULMONARY HYPERTENSION IN COPD
Grant-in-Aid for Scientific Research(C) 2004
A NON-INVASIVE METHOD FOR EVALUATING PULMONARY ENDOTHELIAL CELL APOPTOSIS AND ITS APPLICATION TO THERAPY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Grant-in-Aid for Scientific Research(C) 2003
NEW STRATEGY BASED ON REGULATION OF OXTPATIVE STRESS IN TREATMENT OF BRONCHIAL ASTHMA
Grant-in-Aid for Scientific Research(C) 2001
Respiratory medicine
臨床病態学（呼吸循環系）
2020 Graduate school
呼吸器内科学
2020 Undergraduate
呼吸器内科学
2018 Undergraduate
FD活動への貢献 2018
大阪府医師会及び、その連携医師会の学術講演会
Role(s)： Panelist, Commentator, Host, Lecturer, Consultant, Report author
1990 - Now
Job Career
1986.06 - 1988.03
Job Career
1992.04 - 1993.06
Job Career
1993.06 - 2000.10
Job Career
2000.10 - 2006.07
Job Career
2006.07 - 2009.01
Job Career
2009.01 - Now