Updated on 2022/07/24

写真a

 
TSUKIOKA Takuma
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Lecturer
School of Medicine Department of Medical Science
Title
Lecturer
Affiliation
Institute of Medicine

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Lecturer  2022.04 - Now

  • School of Medicine Department of Medical Science 

    Lecturer  2022.04 - Now

Degree

  • 博士(医学) ( Osaka City University )

Research Areas

  • Life Science / Respiratory surgery

Research Interests

  • 肺門部肺癌に対する前向き観察研究

Research Career

  • 原発性肺癌における転移リンパ節の上皮間葉移行

    2018.04 - 2019.03 

  • 原発性肺癌における全身性筋肉量と予後の関係

    2016.04 - 2018.03 

Professional Memberships

  • The International Association for the Study of Lung Cancer

      Domestic

  • 日本呼吸器内視鏡学会

      Domestic

  • 日本肺癌学会

      Domestic

  • 日本呼吸器外科学会

      Domestic

  • 日本胸部外科学会

      Domestic

  • 日本外科学会

      Domestic

▼display all

Job Career (off-campus)

  • 大阪市立総合医療センター呼吸器外科   医長

    2012.04 - 2016.03

  • ベルランド総合病院呼吸器外科   医長

    2011.04 - 2012.03

  • 大阪市立総合医療センター呼吸器外科   研究医

    2009.04 - 2011.03

  • 関西労災病院胸部外科   研究医

    2003.05 - 2004.03

Education

  • Osaka City University   Doctor's Course   Graduated/Completed

    - 2008.03

  • Osaka City University     Graduated/Completed

    - 2001.03

Papers

  • Combined sleeve lobectomy for centrally located primary lung cancer and lung cancer with hilar lymph node metastasis Jpn J Clin Oncol. 2020 Mar 25

    Takuma Tsukioka

    Japanase journal of clinical oncology   50 ( 7 )   794 - 799   2020.07

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)  

  • Positive correlation between sarcopenia and elevation of neutrophil/lymphocyte ration in pathological stage IIIA(N2-positive) non-small cell lung cancer patients(和訳中) Reviewed

    Tsukioka Takuma, Izumi Nobuhiro, Mizuguchi Shinjiro, Kyukwang Chung, Komatsu Hiroaki, Toda Michihito, Hara Kantaro, Miyamoto Hikaru, Nishiyama Noritoshi

    シュプリンガー・ジャパン(株) General Thoracic and Cardiovascular Surgery   66 ( 12 )   716 - 722   2018.12( ISSN:1863-6705

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    Publishing type:Research paper (scientific journal)  

  • Positive correlation between sarcopenia and elevation of neutrophil/lymphocyte ration in pathological stage IIIA (N2-positive) non-small cell lung cancer patients Reviewed

    Tsukioka Takuma, Izumi Nobuhiro, Mizuguchi Shinjiro, Kyukwang Chung, Komatsu Hiroaki, Toda Michihito, Hara Kantaro, Miyamoto Hikaru, Nishiyama Noritoshi

    GENERAL THORACIC AND CARDIOVASCULAR SURGERY   66 ( 12 )   716 - 722   2018.12( ISSN:1863-6705

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11748-018-0985-z

    PubMed

  • 1cm以下の非小細胞肺癌患者の手術成績に対して複数の悪性腫瘍が及ぼす影響(Impact of multiple malignancies on surgical outcomes in patients with 1 cm or smaller non-small cell lung cancer) Reviewed

    Tsukioka Takuma, Izumi Nobuhiro, Mizuguchi Shinjiro, Kyukwang Chung, Komatsu Hiroaki, Toda Michihito, Hara Kantaro, Miyamoto Hikaru, Nishiyama Noritoshi

    シュプリンガー・ジャパン(株) International Journal of Clinical Oncology   23 ( 1 )   66 - 72   2018.02( ISSN:1341-9625

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    Publishing type:Research paper (scientific journal)  

    1cm以下の非小細胞肺癌(NSCLC)患者の術後臨床転帰に対する複数の悪性腫瘍の影響、ならびに小型NSCLCと悪性腫瘍に対する治療間隔の影響について検討した。根治的肺切除が行われた小型NSCLC患者44例(男性19例、女性25例、年齢41〜80歳)の臨床経過を、後ろ向きに調査した。44例中1例は喀血症状、31例は他の疾患検査、12例は癌スクリーニングでNSCLCが検出された。20例(男性8例、女性12例、年齢41〜80歳)で肺癌、食道癌、乳癌等の複数の悪性疾患が認められた。経過観察期間中央値は68ヵ月で、1例で現NSCLCの再発が見られたが、NSCLCによる死亡例はなく、5年全生存率は90%であった。複数の悪性腫瘍を有する患者は悪性腫瘍の無い患者よりも予後が有意に不良であった。またNSCLCと悪性腫瘍に対する治療間隔が5年未満の患者は、5年以上の患者に比べて予後が有意に不良であった。治療間隔が5年以上の患者の予後は、複数の悪性腫瘍が無い患者と同等であった。単変量および多変量解析では、複数の悪性腫瘍の存在が有意な予後不良因子であった。結論として、小型NSCLCの予後は良好であるが、複数の悪性腫瘍の存在が有意な予後不良因子であり、短い治療間隔と予後不良との間に関連が見られた。

  • Loss of Muscle Mass is a Novel Predictor of Postoperative Early Recurrence in N2-Positive Non-Small-Cell Lung Cancer Reviewed

    Tsukioka Takuma, Izumi Nobuhiro, Kyukwang Chung, Komatsu Hiroaki, Toda Michihito, Hara Kantaro, Nishiyama Noritoshi

    Annals of Thoracic and Cardiovascular Surgery 編集委員会 Annals of Thoracic and Cardiovascular Surgery   2018( ISSN:1341-1098

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    Publishing type:Research paper (scientific journal)  

    <p>Background: We often experienced early recurrence in patients with completely resected N2-positive non-small-cell lung cancer (NSCLC). Loss of muscle mass is a poor prognostic factor in patients with several stages of NSCLC. This study aimed to investigate the relationship between preoperative loss of muscle mass and postoperative early recurrence in patients with N2-positive NSCLC.</p><p>Methods: We retrospectively analyzed 47 male patients with completely resected pathological N2-positive NSCLC. Early recurrence was defined as that diagnosed within 1 year after the operation. We used the L3 muscle index (cross-sectional area of muscle at the L3 level, normalized for height) as a clinical measurement of loss of muscle mass (cutoff value, 52.4 cm<sup>2</sup>/m<sup>2</sup>).</p><p>Results: In all, 18 patients with early recurrence had significantly poorer outcomes compared with those without (<i>P</i> <0.01). In univariate analysis, loss of muscle mass (<i>P</i> = 0.023), carcinoembryonic antigen (CEA) level >5.0 ng/mL (<i>P</i> = 0.002), and absence of postoperative chemotherapy (<i>P</i> = 0.042) were predictors of postoperative early recurrence. In multivariate analysis, loss of muscle mass (<i>P</i> = 0.004) and CEA level >5.0 ng/mL (<i>P</i> = 0.001) were independent predictors.</p><p>Conclusions: Loss of muscle mass is an independent predictor of postoperative early recurrence in pathological N2-positive NSCLC patients.</p>

    DOI: 10.5761/atcs.oa.17-00215

    CiNii Article

  • Attenuation of Bleomycin-Induced Pulmonary Fibrosis in Rats with S-Allyl Cysteine Reviewed

    Tsukioka Takuma, Takemura Shigekazu, Minamiyama Yukiko, Mizuguchi Shinjiro, Toda Michihito, Okada Shigeru

    MOLECULES   22 ( 4 )   2017.04( ISSN:1420-3049

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/molecules22040543

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  • Sarcopenia is a novel poor prognostic factor in male patients with pathological Stage I non-small cell lung cancer Reviewed

    Tsukioka Takuma, Nishiyama Noritoshi, Izumi Nobuhiro, Mizuguchi Shinjiro, Komatsu Hiroaki, Okada Satoshi, Toda Michihito, Hara Kantaro, Ito Ryuichi, Shibata Toshihiko

    JAPANESE JOURNAL OF CLINICAL ONCOLOGY   47 ( 4 )   363 - 368   2017.04( ISSN:0368-2811

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/jjco/hyx009

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  • Surgical outcome of patients with lung cancer involving the left atrium. Reviewed

    Tsukioka T, Takahama M, Nakajima R, Kimura M, Inoue H, Yamamoto R

    International journal of clinical oncology   21 ( 6 )   1046 - 1050   2016.12( ISSN:1341-9625

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10147-016-0992-y

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  • Efficacy of Surgical Airway Plasty for Benign Airway Stenosis. Reviewed

    Tsukioka T, Takahama M, Nakajima R, Kimura M, Inoue H, Yamamoto R

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia   22 ( 1 )   27 - 31   2016( ISSN:1341-1098

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5761/atcs.oa.15-00271

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  • Surgical reconstruction for tuberculous airway stenosis: management for patients with concomitant tracheal malacia. Reviewed

    Tsukioka T, Takahama M, Nakajima R, Kimura M, Tei K, Yamamoto R

    General thoracic and cardiovascular surgery   63 ( 7 )   379 - 85   2015.07( ISSN:1863-6705

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11748-015-0536-9

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  • [Thoracic Drainage Using Nasal Airway for Postoperative Broncho-pleural Fistula]. Reviewed

    Tsukioka T, Takahama M, Nakajima R, Kimura M, Tei K, Yamamoto R

    Kyobu geka. The Japanese journal of thoracic surgery   68 ( 6 )   406 - 9   2015.06( ISSN:0021-5252

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  • Sequential stenting for extensive malignant airway stenosis. Reviewed

    Tsukioka T, Takahama M, Nakajima R, Kimura M, Tei K, Yamamoto R

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia   21 ( 2 )   114 - 8   2015( ISSN:1341-1098

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5761/atcs.oa.14-00187

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  • Resection of a second primary lung cancer in a lobe where small-cell lung cancer was previously treated with chemoradiotherapy: report of a case. Reviewed

    Tsukioka T, Yamamoto R, Takahama M, Nakajima R, Tei K, Okada S, Tada H

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia   20 Suppl   482 - 5   2014( ISSN:1341-1098

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.5761/atcs.cr.13-00002

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  • Intraoperative mechanical and chemical pleurodesis with 50% glucose solution for secondary spontaneous pneumothorax in patients with pulmonary emphysema Reviewed

    TSUKIOKA Takuma, INOUE Kiyotoshi, OKA Hiroko, MIZUGUCHI Shinjiro, MORITA Ryuhei, NISHIYAMA Noritoshi

    Surgery today : the Japanese journal of surgery   43 ( 8 )   889 - 893   2013.08( ISSN:09411291

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    CiNii Article

  • Intraoperative mechanical and chemical pleurodesis with 50 % glucose solution for secondary spontaneous pneumothorax in patients with pulmonary emphysema Reviewed

    Tsukioka Takuma, Inoue Kiyotoshi, Oka Hiroko, Mizuguchi Shinjiro, Morita Ryuhei, Nishiyama Noritoshi

    SURGERY TODAY   43 ( 8 )   889 - 893   2013.08( ISSN:0941-1291

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-013-0497-5

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  • Pleurodesis with a 50% glucose solution in patients with spontaneous pneumothorax in whom an operation is contraindicated. Reviewed

    Tsukioka T, Inoue K, Oka H, Mizuguchi S, Morita R, Nishiyama N

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia   19 ( 5 )   358 - 63   2013( ISSN:1341-1098

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  • Ectopic bone formation in a subsegmental bronchus. Reviewed

    Tsukioka T, Yamamoto R, Takahama M, Nakajima R, Tada H

    General thoracic and cardiovascular surgery   60 ( 9 )   618 - 20   2012.09( ISSN:1863-6705

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11748-012-0065-8

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  • [Stage IV primary lung cancer treated with lobectomy because of refractory ipsilateral pneumothorax]. Reviewed

    Tsukioka T, Inoue K, Oka H, Nishiyama N

    Kyobu geka. The Japanese journal of thoracic surgery   65 ( 9 )   781 - 4   2012.08( ISSN:0021-5252

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  • Preoperative serum oxidative stress marker as a strong indicator of nodal involvement in clinical stage I lung adenocarcinoma Reviewed

    TSUKIOKA Takuma, NISHIYAMA Noritoshi, IWATA Takashi, NAGANO Koshi, TEI Keiko, SUEHIRO Shigefumi

    International journal of clinical oncology   17 ( 3 )   250 - 255   2012.06( ISSN:13419625

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  • Preoperative serum oxidative stress marker as a strong indicator of nodal involvement in clinical stage I lung adenocarcinoma Reviewed

    Tsukioka Takuma, Nishiyama Noritoshi, Iwata Takashi, Nagano Koshi, Tei Keiko, Suehiro Shigefumi

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   17 ( 3 )   250 - 255   2012.06( ISSN:1341-9625

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10147-011-0283-6

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  • Increase in preoperative serum reactive oxygen metabolite levels indicates nodal extension in patients with clinical stage I lung adenocarcinoma Reviewed

    TSUKIOKA Takuma, NISHIYAMA Noritoshi, IWATA Takashi, NAGANO Koshi, MIZUGUCHI Shinjiro, TEI Keiko, WAKASA Kenichi, SUEHIRO Shigefumi

    General thoracic and cardiovascular surgery   59 ( 5 )   335 - 340   2011.05( ISSN:18636705

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  • Increase in preoperative serum reactive oxygen metabolite levels indicates nodal extension in patients with clinical stage I lung adenocarcinoma. Reviewed

    Tsukioka T, Nishiyama N, Iwata T, Nagano K, Mizuguchi S, Tei K, Wakasa K, Suehiro S

    General thoracic and cardiovascular surgery   59 ( 5 )   335 - 40   2011.05( ISSN:1863-6705

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11748-010-0739-z

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  • c-1A期非小細胞肺癌症例における術前血中SLX値測定の意義 Reviewed

    月岡 卓馬, 西山 典利, 岩田 隆, 永野 晃史, 泉 信博, 水口 真二郎, 丁 奎光, 末廣 茂文

    (NPO)日本呼吸器外科学会 日本呼吸器外科学会雑誌   24 ( 6 )   886 - 890   2010.09( ISSN:0919-0945

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    2004年1月から2008年12月に縦隔リンパ節郭清を伴う肺葉切除を施行したc-1A期非小細胞肺癌症例131症例を対象とし、術後病理学的リンパ節転移陰性群と陽性群間の臨床病理学的因子を検討した。男性72例、女性59例、平均年齢67歳。腺癌107例、非腺癌24例であった。pN0症例113例、pN1症例6例、pN2症例12例であった。リンパ節転移陰性例(n=113)および陽性例(n=18)を比較検討すると術前血中SLX値の中央値はそれぞれ21.6U/mlおよび28.5U/mlであり、リンパ節転移陽性例で有意に高値であった(p=0.001)。ROCカーブから血中SLX値についてカットオフ値(26U/ml)を決定し、臨床病理学的因子について多変量解析を行うと血中SLX値のみが独立予測因子であった(リスク比:3.527、p=0.021)。c-1A期非小細胞肺癌症例において術前血中SLX値陽性例は術前精査、術式選択について慎重な検討が必要と考えられた。(著者抄録)

  • Pulmonary metastasis from colorectal carcinoma with hepatic metastasis Reviewed

    TSUKIOKA Takuma, NISHIYAMA Noritoshi, IWATA Takashi, NAGANO Koshi, IZUMI Nobuhiro, MIZUGUCHI Shinjiro, MORITA Ryuhei, INOUE Kiyotoshi, SUEHIRO Shigefumi

    General thoracic and cardiovascular surgery   55 ( 11 )   455 - 460   2007.11( ISSN:18636705

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  • Pulmonary metastasis from colorectal carcinoma with hepatic metastasis. Reviewed

    Tsukioka T, Nishiyama N, Iwata T, Nagano K, Izumi N, Mizuguchi S, Morita R, Inoue K, Suehiro S

    General thoracic and cardiovascular surgery   55 ( 11 )   455 - 60   2007.11( ISSN:1863-6705

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11748-007-0165-z

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  • Early recurrence of completely resected N2-positive non-small-cell lung cancer. Reviewed

    Tsukioka T, Nishiyama N, Iwata T, Izumi N, Mizuguchi S, Morita R, Inoue K, Suehiro S

    General thoracic and cardiovascular surgery   55 ( 3 )   113 - 8   2007.03( ISSN:1863-6705

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11748-006-0082-6

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  • Thymolipoma associated with myasthenia gravis. Reviewed

    Tsukioka T, Inoue K, Iwata T, Mizuguchi S, Morita R, Suehiro S

    General thoracic and cardiovascular surgery   55 ( 1 )   26 - 8   2007.01( ISSN:1863-6705

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  • Local and systemic impacts of pleural oxygen exposure in thoracotomy Reviewed

    Tsukioka Takuma, Takemura Shigekazu, Minamiyama Yukiko, Nishiyama Noritoshi, Mizuguchi Shinjiro, Okada Shigeru, Suehiro Shigefumi

    BIOFACTORS   30 ( 2 )   117 - 128   2007( ISSN:0951-6433

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  • Local and systemic impacts of pleural oxygen exposure in thoracotomy. Reviewed

    Tsukioka T, Takemura S, Minamiyama Y, Nishiyama N, Mizuguchi S, Okada S, Suehiro S

    BioFactors (Oxford, England)   30 ( 2 )   117 - 28   2007( ISSN:0951-6433

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  • A resected case of adrenocorticotropic hormone-producing lung adenocarcinoma Reviewed

    TSUKIOKA Takuma, INOUE Kiyotoshi, IWATA Takashi, MIZUGUCHI Shinjiro, MORITA Ryuhei, SUEHIRO Shigehumi

    The Japanese Association for Chest Surgery, The Journal of the Japanese Association for Chest Surgery   20 ( 5 )   756 - 759   2006.07( ISSN:09190945

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    The patient was a 64-year-old man who had left hemiparesis due to a brain infarction. He had severe hypertension and his serum adrenocorticotropic hormone (ACTH) level was high. A chest roentgenogram and a chest computed tomographic scan revealed a right lung tumor. Histology from a bronchoscopic examination revealed a lung adenocarcinoma (C-T2N0M0 stage IB). A right lower lobectomy with a mediastinal lymph node dissection was performed. Immunohistochemical staining for ACTH was positive in the cancer cells and we diagnosed an ACTH-producing lung adenocarcinoma (p-T2N0M0 stage IB). After the operation, his serum ACTH level decreased and we decreased the antihypertensive drugs. Paraneoplastic syndrome caused by ectopic ACTH production has been reported in association with a variety of malignant tumors. However, most cases involving this syndrome are associated with neuroendocrine tumors such as a small-cell carcinoma or carcinoid of the lung. An ACTH producing lung adenocarcinoma is a rare case. To the best of our knowledge, this is the fifth reported case of an ACTH producing lung adenocarcinoma and the second for which resection had been performed.

    DOI: 10.2995/jacsurg.20.756

    CiNii Article

  • Resected Case of Synovial Sarcoma in the Pleural Cavity Reviewed

    TSUKIOKA Takuma, INOUE Kiyotoshi, IWATA Takashi, MIZUGUCHI Shinjiro, MORITA Ryuhei, SUEHIRO Shigefumi

    日本胸部外科学会雑誌 = The Japanese journal of thoracic and cardiovascular surgery   54 ( 6 )   263 - 266   2006.06( ISSN:13444964

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  • Resected case of synovial sarcoma in the pleural cavity. Reviewed

    Tsukioka T, Inoue K, Iwata T, Mizuguchi S, Morita R, Suehiro S

    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi   54 ( 6 )   263 - 6   2006.06( ISSN:1344-4964

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11748-006-0009-2

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  • [Bronchial artery embolization for treatment of mediastinal hemorrhage after pulmonary resection: report of a case]. Reviewed

    Tsukioka T, Inoue K, Iwata T, Izumi N, Mizuguchi S, Morita R, Suehiro S

    Kyobu geka. The Japanese journal of thoracic surgery   58 ( 13 )   1169 - 72   2005.12( ISSN:0021-5252

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Presentations

  • 原発性肺癌に対する追加術式を伴う気管・気管支形成術 Domestic conference

    月岡卓馬

    第72回日本胸部外科学会定期学術集会  2019.11 

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    Presentation type:Oral presentation (general)  

  • 原発性肺癌に対する拡大気管支形成術 Domestic conference

    月岡卓馬

    第42回日本呼吸器内視鏡学会学術総会  2019.07 

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  • 第42回日本呼吸器内視鏡学会学術総会 Domestic conference

    月岡卓馬

    第35回日本呼吸器外科学会総会  2019.05 

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  • 原発性肺癌に対する気管支・肺動脈形成術の治療成績と工夫 Domestic conference

    月岡卓馬

    第119回日本外科学会定期学術集会  2019.04 

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  • pN2非小細胞肺癌予後良好群で認められる転移リンパ節における間葉系因子の喪失 Domestic conference

    月岡卓馬

    第59回日本肺癌学会学術集会  2018.12 

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  • 転移リンパ節における上皮間葉移行と間葉上皮移行 Domestic conference

    月岡卓馬

    第71回日本胸部外科学会定期学術集会  2018.10 

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  • pStageIIIA(pN2)非小細胞肺癌症例における全身性筋肉量とNeutrophil/Lymphocyte ratioの相関 Domestic conference

    月岡卓馬

    第70回日本胸部外科学会定期学術集会  2017.09 

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  • pN2非小細胞肺癌症例における術前全身性筋肉量の評価 Domestic conference

    月岡卓馬

    第60回関西胸部外科学会  2017.06 

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  • 栄養状態と全身性筋肉量の評価によるPre-cachexiaからCachexiaへの進行予測 Domestic conference

    月岡卓馬

    第117回日本外科学会定期学術集会  2017.04 

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  • Sarcopenia は70歳以上の非小細胞肺癌例における予後不良因子である(回帰式を用いたL3 muscle indexの算出) Domestic conference

    月岡卓馬

    第57回日本肺癌学会学術集会  2016.12 

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  • pStageI期非小細胞肺癌症例におけるSarcopeniaと予後の関係-回帰式を用いた骨格筋断面積およびL3 muscle indexの算出- Domestic conference

    月岡卓馬

    第69回日本胸部外科学会定期学術集会  2016.10 

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    Presentation type:Oral presentation (general)  

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Outline of education staff

  • 早期臨床実習 基本的臨床手技(医学部4年生)
    ユニット型クリニカルクラークシップ ユニットA呼吸器外科分野担当(医学部5年生)

Charge of on-campus class subject

  • 早期臨床実習

    2019     Undergraduate

  • ユニット型クリニカルクラークシップ ユニットA 呼吸器外科

    2019     Undergraduate

Other

  • Job Career

    2016.04 - 2016.12

  • Job Career

    2008.04 - 2009.03

  • Job Career

    2004.04 - 2008.03

  • Job Career

    2001.05 - 2003.04