Researcher Profiles - ITO Asahiro

写真a

ITO Asahiro

Organization

Graduate School of Medicine Department of Clinical Medical Science Lecturer
School of Medicine Department of Medical Science

Affiliation

Institute of Medicine

Position

Graduate School of Medicine Department of Clinical Medical Science

Lecturer 2022.04 - Now
School of Medicine Department of Medical Science

Lecturer 2022.04 - Now

Research Areas

Life Science / Cardiology

Research Interests

Structural Heart Disease

Professional Memberships

THE JAPAN SOCIETY OF ULTRASONICS IN MEDICINE
JAPANESE SOCIETY OF ECHOCARDIOGRAPHY
The Japanese Circulation Society
THE JAPANESE SOCIETY OF INTERNAL MEDICINE
THE JAPANESE SOCIETY OF INTERNAL MEDICINE

Domestic
The Japanese Circulation Society

Domestic
THE JAPAN SOCIETY OF ULTRASONICS IN MEDICINE

Domestic
JAPANESE SOCIETY OF ECHOCARDIOGRAPHY

Domestic

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Awards

医学会賞

伊藤朝広

2015.03 大阪市医学会
AHA Funded Researcher

ito asahiro

2012.11 American Heart Association Scientific Sessions 2012

Job Career (off-campus)

大阪市立大学大学院医学研究科循環器内科学

2020.04 - Now
Osaka City University Graduate School of Medicine, Clinical Medicine Course

2017.04 - 2020.03

Papers

'Conventional' haemodynamics even in the quadricuspid aortic valve: clinical recognition using multimodality imaging. Reviewed

Wakasa S, Ito A, Kitada R, Takahashi Y, Fukuda D

European heart journal. Cardiovascular Imaging 2023.04（ ISSN:2047-2404 ）

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Authorship：Lead author,　Corresponding author

DOI： 10.1093/ehjci/jead081

PubMed
Endoscopic assessment of WATCHMAN 17 months after implantation. Reviewed

Takanori Yamazaki, Tomotaka Yoshiyama, Asahiro Ito, Yasuhiro Izumiya, Daiju Fukuda

Cardiovascular intervention and therapeutics 38 ( 2 ) 258 - 259 2023.04（ ISSN:18684300 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：Domestic journal

DOI： 10.1007/s12928-022-00902-x

PubMed
Impact of cystatin C-derived glomerular filtration rate in patients undergoing transcatheter aortic valve implantation. Reviewed

Kure Y, Okai T, Izumiya Y, Yoshida H, Mizutani K, Yamaguchi T, Ogawa M, Shibata A, Ito A, Takahashi Y, Shibata T, Fukuda D

Frontiers in cardiovascular medicine 10 1035736 2023（ ISSN:2297-055X ）

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Authorship：Lead author,　Corresponding author

DOI： 10.3389/fcvm.2023.1035736

PubMed
夜間血圧、夜間心拍と心血管疾患患者の予後予測に関する検討 Reviewed

キム・アンドリュー・ティー, 伊藤朝広, 伊藤文花, 小川真奈, 北田諒子, 石川世良, 岩田真一, 泉家康宏, 福田大受

日本心臓病学会学術集会抄録 70回 O - 4 2022.09
24時間自由行動下血圧測定での血圧変動性と心房細動カテーテルアブレーション後の再発に関する検討 Reviewed

伊藤文花, 伊藤朝広, キム・アンドリュー・ティー, 小川真奈, 北田諒子, 石川世良, 岩田真一, 泉家康宏, 福田大受

日本心臓病学会学術集会抄録 70回 O - 2 2022.09
ペーシング誘発性心筋症の危険因子　リードの位置からの洞察(Risk factors of pacing-induced cardiomyopathy-Insights from lead position) Reviewed

Yoshiyama Tomotaka, Shimeno Kenji, Hayashi Yusuke, Ito Asahiro, Iwata Shinichi, Matsumura Yoshiki, Izumiya Yasuhiro, Abe Yukio, Ehara Shoichi, Naruko Takahiko

Journal of Arrhythmia 38 ( 3 ) 408 - 415 2022.06（ ISSN:1880-4276 ）

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Authorship：Lead author,　Corresponding author

ペーシング誘発性心筋症(PICM)の予測因子を後方視的観察研究で調べた。2008年1月～2018年1月にペースメーカー植込み目的で紹介された連続患者604名のうち、適格とした172名(男性88名、平均76±11歳)を組み入れた。リードの位置は右室心尖部(RVA)または右室中隔中部(mid-RVS)とし、mid-RVSの場合はその設置位置をCTで確認した。PICMの定義は、経過観察時の経胸壁心エコー法による評価で左室駆出率が40%未満とした。PICMを発症していた患者は18名(10.5%)(男性14名、平均76±14歳)存在した。RVA群66名とmid-RVS群106名を比較した場合、ペーシング時のQRS幅はmid-RVS群の方が有意に短かったものの、PICM発症率には有意差は認められなかった。多変量解析の結果、PICMの独立予測因子として、術前の左室収縮末期径(HR 1.12、95%CI 1.03～1.22)とペーシング時のQRS幅(HR 1.03、95%CI 1.004～1.06)が同定された。結論として、RVAかmid-RVSかというリードの設置位置の違いは、PICMの予測因子とはなっていなかった。術前の左室収縮末期径とペーシング時のQRS幅は、PICM予測に有用な指標となる可能性が示された。
経カテーテル大動脈弁置換術を施行する患者の転帰を予測するには基本チェックリストが有用である(Kihon checklist is useful for predicting outcomes in patients undergoing transcatheter aortic valve implantation) Reviewed

Kure Yusuke, Okai Tsukasa, Izumiya Yasuhiro, Shimizu Masashi, Yahiro Ryosuke, Yamaguchi Tomohiro, Ogawa Mana, Kishimoto Noriaki, Shibata Atsushi, Ito Asahiro, Takahashi Yosuke, Ehara Shoichi, Shibata Toshihiko, Yoshiyama Minoru

Journal of Cardiology 79 ( 1-2 ) 299 - 305 2022.02（ ISSN:0914-5087 ）

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Authorship：Lead author,　Corresponding author

大動脈弁狭窄症(AS)に対し経カテーテル大動脈弁置換術(TAVI)を行う患者において、フレイルの存在が3年後の予後に及ぼす影響を評価する前向き観察研究を施行した。当院でTAVIを行う重症ASの患者連続280名(女性率68.9%、年齢中央値84歳)を組み入れた。TAVI手技の前に、患者に基本チェックリスト(KCL)へ回答してもらうことでフレイルの評価を行った。KCLは「はい/いいえ」で回答する簡単な質問文25個で構成され、0～25点の範囲でスコア評価されるものであった。主要評価項目はTAVIから3年後の全死因死亡率とした。KCLの他に3種の尺度も用いてフレイル評価を行ったが、フレイル状態に関する受信者動作特性(ROC)曲線解析において、KCLスコアが示すROC曲線と、他の各尺度によるROC曲線の間には有意な差は認められなかった。KCLスコアで本集団がほぼ3等分になるよう層別化した時の三分位数は、8点と12点であった。多変量Cox回帰分析の結果、3年全死因死亡の有意な独立関連因子として、KCLスコア(ハザード比[HR]1.10、95%CI 1.03～1.18)、糖尿病(HR 2.0)、肝疾患(HR 3.0)、が同定された。TAVIを行う患者でフレイルを評価し3年全死因死亡を予測する上で、KCLは簡便で有用なツールになると結論された。
Kihon checklist is useful for predicting outcomes in patients undergoing transcatheter aortic valve implantation. Reviewed

Yusuke Kure, Tsukasa Okai, Yasuhiro Izumiya, Masashi Shimizu, Ryosuke Yahiro, Tomohiro Yamaguchi, Mana Ogawa, Noriaki Kishimoto, Atsushi Shibata, Asahiro Ito, Yosuke Takahashi, Shoichi Ehara, Toshihiko Shibata, Minoru Yoshiyama

Journal of cardiology 79 ( 2 ) 299 - 305 2022.02

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

BACKGROUND: Frailty is a major risk factor for death and disability following transcatheter aortic valve implantation (TAVI). The Kihon checklist (KCL) is a simple self-reporting yes/no survey consisting of 25 questions and is used as a screening tool to identify frailty in the primary care setting. No clinical studies have focused on frailty calculated by the KCL in the TAVI cohort. We investigated the 3-year prognostic impact of frailty evaluated by the KCL in patients who underwent TAVI. METHODS: This single-center prospective observational study included 280 consecutive patients with symptomatic severe aortic stenosis who underwent TAVI and evaluated pre-procedural physical performance focused on frailty at our institution. We assessed all patients' frailty by the KCL before TAVI, as described previously. We set the primary endpoint as the 3-year all-cause mortality after TAVI. RESULTS: The median patient age was 84 years (interquartile range, 81-87 years), and 31.1% were men. In the receiver operating characteristics curve, there were no significant differences between the KCL and Cardiovascular Health Study frailty index [area under the curve (AUC) 0.625 versus 0.628; p=0.93), KCL and Rockwood Clinical Frailty Scale (AUC 0.625 versus 0.542; p=0.15), and KCL and Short Physical Performance Battery (AUC 0.625 versus 0.612; p=0.91). The first and second tertiles of the total KCL score were 8 and 12, respectively. The multivariate Cox regression model indicated that the total KCL score [hazard ratio (HR), 1.104; 95% confidence interval (CI), 1.034-1.179; p=0.003], presence of diabetes mellitus (HR, 1.993; CI, 1.055-3.766; p=0.03), and presence of liver disease (HR, 3.007; CI, 1.067-8.477; p=0.04) were independently associated with 3-year all-cause mortality. CONCLUSIONS: The KCL is a simple and useful tool for evaluating frailty status and predicting 3-year all-cause mortality in patients undergoing TAVI.

DOI： 10.1016/j.jjcc.2021.09.014

PubMed
Difference in risk factors of silent brain infarction between paroxysmal and persistent atrial fibrillation. Reviewed

Kim AT, Iwata S, Ishikawa S, Tamura S, Matsuo M, Yoshiyama T, Nonin S, Ito A, Izumiya Y, Yoshiyama M

International journal of cardiology. Heart & vasculature 33 100753 2021.04

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Publishing type：Research paper (scientific journal)

DOI： 10.1016/j.ijcha.2021.100753

PubMed
シスタチンCから算出した腎機能とTAVI後の予後の検討 Reviewed

岡井主, 水谷一輝, 八尋亮介, 山口智大, 小川真奈, 能仁信一, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 29回 1057 - 1057 2021.02
Bacteremic cellulitis mimicking erythema nodosum caused by Streptococcus sanguinis endocarditis Reviewed

Nishida Marina, Imanishi Hisayoshi, Sowa-Osako Junko, Umeda Sakurako, Ito Asahiro, Yasumizu Daisuke, Yoshiyama Minoru, Tsuruta Daisuke

INTERNATIONAL JOURNAL OF DERMATOLOGY 59 ( 11 ) E425 - E427 2020.11（ ISSN:0011-9059 ）

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Publishing type：Research paper (scientific journal)

DOI： 10.1111/ijd.14973

PubMed
Prevalence and Risk Factors of Silent Brain Infarction in Patients with Aortic Stenosis. Reviewed

Ayaka Ito, Shinichi Iwata, Soichiro Tamura, Andrew T Kim, Shinichi Nonin, Sera Ishikawa, Asahiro Ito, Yasuhiro Izumiya, Takato Abe, Toshihiko Shibata, Minoru Yoshiyama

Cerebrovascular diseases extra 10 ( 3 ) 116 - 123 2020.10

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

INTRODUCTION: Silent brain infarction (SBI) is an independent risk factor for subsequent symptomatic stroke in the general population. Although aortic stenosis (AS) is also known to be associated with an increased risk of future symptomatic stroke, little is known regarding the prevalence and risk factors for SBI in patients with AS. METHODS: The study population comprised 83 patients with severe AS with no history of stroke or transient ischemic attack and paralysis or sensory impairment (mean age 75 ± 7 years). All patients underwent brain magnetic resonance imaging to screen for SBI and multidetector-row computed tomography to quantify the aortic valve calcification (AVC) volume. Comprehensive transthoracic and transesophageal echocardiography were performed to evaluate left atrial (LA) abnormalities, such as LA enlargement, spontaneous echo contrast, or abnormal LA appendage emptying velocity (<20 cm/s), and complex plaques in the aortic arch. RESULTS: SBI was detected in 38 patients (46%). Multiple logistic regression analysis indicated that CHA2DS2-VASc score and estimated glomerular filtration rate (eGFR) were independently associated with SBI (p < 0.05), whereas LA abnormalities and AVC volume were not. When patients were divided into 4 groups according to CHA2DS2-VASc score and eGFR, the group with a higher CHA2DS2-VASc score (≥4) and a lower eGFR (<60 mL/min/1.73 m2) had a greater risk of SBI than the other groups (p < 0.05). CONCLUSION: These findings indicate that AS is associated with a high prevalence of SBI, and that the CHA2DS2-VASc score and eGFR are useful for risk stratification.

DOI： 10.1159/000510438

PubMed
Presence of mitral stenosis is a risk factor of new development of acute decompensated heart failure early after transcatheter aortic valve implantation. Reviewed

Tsukasa Okai, Kazuki Mizutani, Masahiko Hara, Tomohiro Yamaguchi, Mana Ogawa, Asahiro Ito, Shinichi Iwata, Yasuhiro Izumiya, Yosuke Takahashi, Toshihiko Shibata, Minoru Yoshiyama

Open heart 7 ( 2 ) 2020.10

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

AIMS: Acute decompensated heart failure (ADHF) can occur early after transcatheter aortic valve implantation (TAVI), but the risk factors or mechanisms associated with it have not been fully determined. This hypothesis-generating study aimed to investigate the clinical indices associated with the development of ADHF within 72 hours after TAVI and to improve procedural approaches for TAVI. METHOD AND RESULTS: In this single-centre hypothesis generating prospective observational study, we enrolled 156 consecutive patients with severe aortic stenosis who underwent TAVI between January 2016 and February 2018 at our institution. We set the primary endpoint as the new development of ADHF within 72 hours after TAVI, and clinical indices associated with it were evaluated using a multivariable logistic model. The median age of the patients was 83 (quartile range 80-86) years, 48 (30.8%) were men and the median Society of Thoracic Surgery-Predicted Risk of Mortality was 7.1 (range 5.2-10.4). Mitral stenosis (MS), defined as mean transmitral valve pressure gradient ≥5 mm Hg, was present in 15 (9.6%) patients. After TAVI, the invasive mean transaortic valve pressure gradient (mAVPG) decreased from 48 (36-66) to 7 (5-11) mm Hg, and 12 (7.7%) patients developed ADHF within 72 hours after TAVI. Multivariable logistic regression analysis showed that MS (adjusted OR, 14.227; 95% CI 2.654 to 86.698; p=0.002) and greater decreases in mAVPG (1.038; 1.003 to 1.080; p=0.044) were associated with ADHF. CONCLUSIONS: MS and drastic improvement of mAVPG were associated with new development of ADHF within 72 hours after TAVI.

DOI： 10.1136/openhrt-2020-001348

PubMed
Irreversible reversal of aortic valve leaflet during transcatheter aortic valve implantation Reviewed

Ogawa Mana, Mizutani Kazuki, Okai Tsukasa, Ito Asahiro, Iwata Shinichi, Yoshiyama Minoru

CARDIOVASCULAR INTERVENTION AND THERAPEUTICS 2020.09（ ISSN:1868-4300 ）

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Publishing type：Research paper (scientific journal)

DOI： 10.1007/s12928-020-00700-3

PubMed
Irreversible reversal of aortic valve leaflet during transcatheter aortic valve implantation. Reviewed

Mana Ogawa, Kazuki Mizutani, Tsukasa Okai, Asahiro Ito, Shinichi Iwata, Minoru Yoshiyama

Cardiovascular intervention and therapeutics 2020.09

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Publishing type：Research paper (scientific journal) International / domestic magazine：Domestic journal

DOI： 10.1007/s12928-020-00700-3

PubMed
Bacteremic cellulitis mimicking erythema nodosum caused by Streptococcus sanguinis endocarditis. Reviewed

Marina Nishida, Hisayoshi Imanishi, Junko Sowa-Osako, Sakurako Umeda, Asahiro Ito, Daisuke Yasumizu, Minoru Yoshiyama, Daisuke Tsuruta

International journal of dermatology 59 ( 11 ) e425-e427 2020.06

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International / domestic magazine：International journal

DOI： 10.1111/ijd.14973

PubMed
POST-PROCEDURAL CARDIO-ANKLE VASCULAR INDEX IS ASSOCIATED WITH ONE-YEAR MORTALITY IN PATIENTS WHO UNDERWENT TRANS-FEMORAL TAVR Reviewed

Yamaguchi Tomohiro, Mizutani Kazuki, Yahiro Ryousuke, Ogawa Mana, Okai Tsukasa, Nonin Shinichi, Ito Asahiro, Iwata Shinichi, Izumiya Yasuhiro, Takahashi Yosuke, Shibata Toshihiko, Yoshiyama Minoru

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 75 ( 11 ) 1243 - 1243 2020.03（ ISSN:0735-1097 ）

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Publishing type：Research paper (scientific journal)
Predictors of increased d-dimer level at follow-up period after transcatheter aortic valve implantation.Is oral anticoagulation therapy better? Reviewed

Okai T., Mizutani K., Yamaguchi T., Ogawa M., Kajio K., Ito A., Iwata S., Takahashi Y., Izumiya Y., Murakami T., Shibata T., Yoshiyama M.

EUROPEAN HEART JOURNAL 41 53 - 53 2020.01（ ISSN:0195-668X ）

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Publishing type：Research paper (scientific journal)

DOI： 10.1093/ehjci/ehz872.050
Presence of mitral stenosis is a risk factor of new development of acute decompensated heart failure early after transcatheter aortic valve implantation Reviewed

Okai Tsukasa, Mizutani Kazuki, Hara Masahiko, Yamaguchi Tomohiro, Ogawa Mana, Ito Asahiro, Iwata Shinichi, Izumiya Yasuhiro, Takahashi Yosuke, Shibata Toshihiko, Yoshiyama Minoru

OPEN HEART 7 ( 2 ) 2020（ ISSN:2053-3624 ）

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Publishing type：Research paper (scientific journal)

AIMS: Acute decompensated heart failure (ADHF) can occur early after transcatheter aortic valve implantation (TAVI), but the risk factors or mechanisms associated with it have not been fully determined. This hypothesis-generating study aimed to investigate the clinical indices associated with the development of ADHF within 72 hours after TAVI and to improve procedural approaches for TAVI. METHOD AND RESULTS: In this single-centre hypothesis generating prospective observational study, we enrolled 156 consecutive patients with severe aortic stenosis who underwent TAVI between January 2016 and February 2018 at our institution. We set the primary endpoint as the new development of ADHF within 72 hours after TAVI, and clinical indices associated with it were evaluated using a multivariable logistic model. The median age of the patients was 83 (quartile range 80-86) years, 48 (30.8%) were men and the median Society of Thoracic Surgery-Predicted Risk of Mortality was 7.1 (range 5.2-10.4). Mitral stenosis (MS), defined as mean transmitral valve pressure gradient ≥5 mm Hg, was present in 15 (9.6%) patients. After TAVI, the invasive mean transaortic valve pressure gradient (mAVPG) decreased from 48 (36-66) to 7 (5-11) mm Hg, and 12 (7.7%) patients developed ADHF within 72 hours after TAVI. Multivariable logistic regression analysis showed that MS (adjusted OR, 14.227; 95% CI 2.654 to 86.698; p=0.002) and greater decreases in mAVPG (1.038; 1.003 to 1.080; p=0.044) were associated with ADHF. CONCLUSIONS: MS and drastic improvement of mAVPG were associated with new development of ADHF within 72 hours after TAVI.

DOI： 10.1136/openhrt-2020-001348

PubMed
Prevalence and Risk Factors of Silent Brain Infarction in Patients with Aortic Stenosis Reviewed

Ito Ayaka, Iwata Shinichi, Tamura Soichiro, Kim Andrew T., Nonin Shinichi, Ishikawa Sera, Ito Asahiro, Izumiya Yasuhiro, Abe Takato, Shibata Toshihiko, Yoshiyama Minoru

CEREBROVASCULAR DISEASES EXTRA 10 ( 3 ) 116 - 123 2020（ ISSN:1664-5456 ）

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Publishing type：Research paper (scientific journal)

INTRODUCTION: Silent brain infarction (SBI) is an independent risk factor for subsequent symptomatic stroke in the general population. Although aortic stenosis (AS) is also known to be associated with an increased risk of future symptomatic stroke, little is known regarding the prevalence and risk factors for SBI in patients with AS. METHODS: The study population comprised 83 patients with severe AS with no history of stroke or transient ischemic attack and paralysis or sensory impairment (mean age 75 ± 7 years). All patients underwent brain magnetic resonance imaging to screen for SBI and multidetector-row computed tomography to quantify the aortic valve calcification (AVC) volume. Comprehensive transthoracic and transesophageal echocardiography were performed to evaluate left atrial (LA) abnormalities, such as LA enlargement, spontaneous echo contrast, or abnormal LA appendage emptying velocity (<20 cm/s), and complex plaques in the aortic arch. RESULTS: SBI was detected in 38 patients (46%). Multiple logistic regression analysis indicated that CHA2DS2-VASc score and estimated glomerular filtration rate (eGFR) were independently associated with SBI (p < 0.05), whereas LA abnormalities and AVC volume were not. When patients were divided into 4 groups according to CHA2DS2-VASc score and eGFR, the group with a higher CHA2DS2-VASc score (≥4) and a lower eGFR (<60 mL/min/1.73 m2) had a greater risk of SBI than the other groups (p < 0.05). CONCLUSION: These findings indicate that AS is associated with a high prevalence of SBI, and that the CHA2DS2-VASc score and eGFR are useful for risk stratification.

DOI： 10.1159/000510438

PubMed
Self-expandable transcatheter aortic valve implantation is associated with frequent periprocedural stroke detected by diffusion-weighted magnetic resonance imaging-Insight from propensity score match Reviewed

Ogawa M., Mizutani K., Okai T., Kajio K., Ito A., Iwata S., Takahashi Y., Murakami T., Shibata T., Yoshiyama M.

EUROPEAN HEART JOURNAL 40 2293 - 2293 2019.10（ ISSN:0195-668X ）

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自己拡張型経カテーテル大動脈弁置換術は、拡散強調MRIにより検出される頻繁な周術期脳卒中と関連する(Self-expandable transcatheter aortic valve replacement is associated with frequent periprocedural stroke detected by diffusion-weighted magnetic resonance imaging)

Kajio Keiko, Mizutani Kazuki, Hara Masahiko, Nakao Mana, Okai Tsukasa, Ito Asahiro, Takahashi Yosuke, Iwata Shinichi, Shimono Taro, Izumiya Yasuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

Journal of Cardiology 74 ( 1-2 ) 27 - 33 2019.08（ ISSN:0914-5087 ）

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経大腿動脈的経カテーテル大動脈弁置換術(TAVR)を受ける患者113例(男性36.3%、年齢81〜87歳)を対象に、拡散強調MRI(DW-MRI)で検出される術後脳卒中のリスクを評価した。バルーン拡張型弁を第一選択治療として93例に使用し、狭いバルサルバ洞・上行大動脈接合部または弁輪を有する20例に自己拡張型弁を選択した。主要評価項目は、サイズに関係なく、DW-MRIにより検出される高信号域(HIA)の数であった。113例のうち症候性脳卒中は6例(5.3%)、無症候性脳卒中は59例(52.2%)に発生した。症候性脳卒中および総脳卒中の発生率は、自己拡張型TAVRを受けた患者の方がバルーン拡張型TAVRを受けた患者より有意に高かった(それぞれ30.0% vs.0.0%、90.0% vs.50.5%)。多変量線形回帰モデルにより自己拡張型TAVRと主要評価項目に関連が認められ、その他の共変量は主要評価項目と有意な関係がみられなかった。赤池情報基準ベースのステップワイズ統計モデル選択により、弁の種類が最適予測モデルに対する唯一の説明変数であることが示された。
自己拡張型経カテーテル大動脈弁置換術は、拡散強調MRIにより検出される頻繁な周術期脳卒中と関連する(Self-expandable transcatheter aortic valve replacement is associated with frequent periprocedural stroke detected by diffusion-weighted magnetic resonance imaging) Reviewed

Kajio Keiko, Mizutani Kazuki, Hara Masahiko, Nakao Mana, Okai Tsukasa, Ito Asahiro, Takahashi Yosuke, Iwata Shinichi, Shimono Taro, Izumiya Yasuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

(一社)日本心臓病学会　Journal of Cardiology 74 ( 1-2 ) 27 - 33 2019.08（ ISSN:0914-5087 ）

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Publishing type：Research paper (scientific journal)

経大腿動脈的経カテーテル大動脈弁置換術(TAVR)を受ける患者113例(男性36.3%、年齢81〜87歳)を対象に、拡散強調MRI(DW-MRI)で検出される術後脳卒中のリスクを評価した。バルーン拡張型弁を第一選択治療として93例に使用し、狭いバルサルバ洞・上行大動脈接合部または弁輪を有する20例に自己拡張型弁を選択した。主要評価項目は、サイズに関係なく、DW-MRIにより検出される高信号域(HIA)の数であった。113例のうち症候性脳卒中は6例(5.3%)、無症候性脳卒中は59例(52.2%)に発生した。症候性脳卒中および総脳卒中の発生率は、自己拡張型TAVRを受けた患者の方がバルーン拡張型TAVRを受けた患者より有意に高かった(それぞれ30.0% vs.0.0%、90.0% vs.50.5%)。多変量線形回帰モデルにより自己拡張型TAVRと主要評価項目に関連が認められ、その他の共変量は主要評価項目と有意な関係がみられなかった。赤池情報基準ベースのステップワイズ統計モデル選択により、弁の種類が最適予測モデルに対する唯一の説明変数であることが示された。
Self-expandable transcatheter aortic valve replacement is associated with frequent periprocedural stroke detected by diffusion-weighted magnetic resonance imaging Reviewed

Kajio Keiko, Mizutani Kazuki, Hara Masahiko, Nakao Mana, Okai Tsukasa, Ito Asahiro, Takahashi Yosuke, Iwata Shinichi, Shimono Taro, Izumiya Yasuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

JOURNAL OF CARDIOLOGY 74 ( 1 ) 27 - 33 2019.07（ ISSN:0914-5087 ）

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BACKGROUND: Little evidence is available regarding the risk of peri-procedural stroke detected by diffusion-weighted magnetic resonance imaging (DW-MRI) after transcatheter aortic valve replacement (TAVR). Our purpose was to evaluate stroke risk after TAVR using DW-MRI by enrolling consecutive patients who underwent transfemoral TAVR and post-procedural DW-MRI. METHODS: We prospectively enrolled 113 consecutive patients who underwent transfemoral TAVR and post-procedural DW-MRI. We used balloon-expandable valves as first-line therapy and selected self-expandable valves only for patients with narrow sinotubular junctions or annuli. We set the primary endpoint as the number of high intensity areas (HIA) detected by DW-MRI regardless of the size of the area. To evaluate the risks of the primary endpoint, we employed a multivariable linear regression model, setting the primary endpoint as an objective variable and patient and clinical backgrounds as explanatory variables. RESULTS: Median patient age was 84 years, and 36.3% were men. Ninety-three patients underwent balloon-expandable TAVR and 20 underwent self-expandable TAVR. Symptomatic stroke occurred in 6 (5.3%) whereas asymptomatic stroke occurred in 59 (52.2%) patients. The incidence of symptomatic and total stroke was higher in patients who underwent self-expandable TAVR than those who underwent balloon-expandable TAVR (30.0% vs. 0.0%, p<0.001 and 90.0% vs. 50.5%, p=0.001, respectively). A multivariable linear regression model demonstrated an increased primary endpoint when self-expandable TAVR was performed (p<0.001). The other covariates had no significant relationship to the primary endpoint. Akaike information criterion-based stepwise statistical model selection revealed that valve type was the only explanatory variable for the best predictive model. CONCLUSIONS: Self-expandable valves were associated with increased numbers of HIA on DW-MRI after TAVR in patients with severe aortic stenosis.

DOI： 10.1016/j.jjcc.2019.01.013

PubMed
Self-expandable transcatheter aortic valve replacement is associated with frequent periprocedural stroke detected by diffusion-weighted magnetic resonance imaging. Reviewed

Keiko Kajio, Kazuki Mizutani, Masahiko Hara, Mana Nakao, Tsukasa Okai, Asahiro Ito, Yosuke Takahashi, Shinichi Iwata, Taro Shimono, Yasuhiro Izumiya, Takashi Murakami, Toshihiko Shibata, Minoru Yoshiyama

Journal of cardiology 74 ( 1 ) 27 - 33 2019.07（ ISSN:0914-5087 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

BACKGROUND: Little evidence is available regarding the risk of peri-procedural stroke detected by diffusion-weighted magnetic resonance imaging (DW-MRI) after transcatheter aortic valve replacement (TAVR). Our purpose was to evaluate stroke risk after TAVR using DW-MRI by enrolling consecutive patients who underwent transfemoral TAVR and post-procedural DW-MRI. METHODS: We prospectively enrolled 113 consecutive patients who underwent transfemoral TAVR and post-procedural DW-MRI. We used balloon-expandable valves as first-line therapy and selected self-expandable valves only for patients with narrow sinotubular junctions or annuli. We set the primary endpoint as the number of high intensity areas (HIA) detected by DW-MRI regardless of the size of the area. To evaluate the risks of the primary endpoint, we employed a multivariable linear regression model, setting the primary endpoint as an objective variable and patient and clinical backgrounds as explanatory variables. RESULTS: Median patient age was 84 years, and 36.3% were men. Ninety-three patients underwent balloon-expandable TAVR and 20 underwent self-expandable TAVR. Symptomatic stroke occurred in 6 (5.3%) whereas asymptomatic stroke occurred in 59 (52.2%) patients. The incidence of symptomatic and total stroke was higher in patients who underwent self-expandable TAVR than those who underwent balloon-expandable TAVR (30.0% vs. 0.0%, p<0.001 and 90.0% vs. 50.5%, p=0.001, respectively). A multivariable linear regression model demonstrated an increased primary endpoint when self-expandable TAVR was performed (p<0.001). The other covariates had no significant relationship to the primary endpoint. Akaike information criterion-based stepwise statistical model selection revealed that valve type was the only explanatory variable for the best predictive model. CONCLUSIONS: Self-expandable valves were associated with increased numbers of HIA on DW-MRI after TAVR in patients with severe aortic stenosis.

DOI： 10.1016/j.jjcc.2019.01.013

PubMed
Arterial inflow line equipped with a side arm for circulatory support and catheter insertion during transcatheter aortic valve implantation for limited vascular access Reviewed

Murakami Takashi, Sada Ryoji, Takahashi Yosuke, Nishimura Shinsuke, Mizutani Kazuki, Ito Asahiro, Iwata Shinichi, Yamada Tokuhiro, Yoshiyama Minoru, Shibata Toshihiko

GENERAL THORACIC AND CARDIOVASCULAR SURGERY 67 ( 3 ) 328 - 331 2019.03（ ISSN:1863-6705 ）

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Transcatheter aortic valve implantation was performed on a 78-year-old patient. Elective circulatory support with cardiopulmonary bypass was planned because of left ventricular function impairment and hemodynamic instability. Limited vascular access was due to a severe atherosclerotic aorta distal to the origin of the left carotid artery. The right arm was the only safe vascular access site. However, at least 2 vascular access sites for angiographic catheter and inflow of circulatory support were required. An arterial inflow line equipped with a side arm was developed to enable single access to the right axillary artery to be used for the above purposes.

DOI： 10.1007/s11748-018-0905-2

PubMed
バスキュラーアクセスの造設部位が限られた患者における経カテーテル大動脈弁置換術のための循環サポートとカテーテル挿入用の分岐連結管を装着した動脈ライン(Arterial inflow line equipped with a side arm for circulatory support and catheter insertion during transcatheter aortic valve implantation for limited vascular access) Reviewed

Murakami Takashi, Sada Ryoji, Takahashi Yosuke, Nishimura Shinsuke, Mizutani Kazuki, Ito Asahiro, Iwata Shinichi, Yamada Tokuhiro, Yoshiyama Minoru, Shibata Toshihiko

シュプリンガー・ジャパン(株)　General Thoracic and Cardiovascular Surgery 67 ( 3 ) 328 - 331 2019.03（ ISSN:1863-6705 ）

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症例は78歳男性で、重度の心不全のため当院へ搬送された。脳卒中とステージ4の慢性腎臓病の既往があり、経皮的冠動脈インターベンションの手術歴があった。心エコー検査で大動脈弁狭窄症を認め、大動脈弁口面積は0.68cm2、左室の拡張末期径は61mm、駆出率は20%であった。中等度の僧帽弁閉鎖不全も認めた。造影CT検査で左総頸動脈の起始部から内臓枝の分岐部にかけて重度のアテローム性動脈硬化を認め、また下行大動脈遠位部にアテローム性動脈硬化と石灰化を認めた。MRI検査で左内頸動脈と左椎骨動脈の閉塞と右総頸動脈の重度狭窄を認めた。開腹手術は困難と判断し、経カテーテル大動脈弁置換術を施行した。大動脈と左総頸動脈は重度のアテローム性動脈硬化のため塞栓リスクが高く、バスキュラーアクセスの作成は右腕に限られていた。全身麻酔下に人工心肺装置を接続し、右腕に右腋窩動脈送血のための動脈ラインを確保し、Y字連結管を使ってカテーテル挿入ポートを分岐連結した。脱血カニューレは右大腿静脈から右房に挿入した。カテーテル挿入ポートからSAPIEN XT生体弁を留置した。手術は成功し、術後16日目に転院となった。
Arterial inflow line equipped with a side arm for circulatory support and catheter insertion during transcatheter aortic valve implantation for limited vascular access. Reviewed

Takashi Murakami, Ryoji Sada, Yosuke Takahashi, Shinsuke Nishimura, Kazuki Mizutani, Asahiro Ito, Shinichi Iwata, Tokuhiro Yamada, Minoru Yoshiyama, Toshihiko Shibata

General thoracic and cardiovascular surgery 67 ( 3 ) 328 - 331 2019.03（ ISSN:1863-6705 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：Domestic journal

Transcatheter aortic valve implantation was performed on a 78-year-old patient. Elective circulatory support with cardiopulmonary bypass was planned because of left ventricular function impairment and hemodynamic instability. Limited vascular access was due to a severe atherosclerotic aorta distal to the origin of the left carotid artery. The right arm was the only safe vascular access site. However, at least 2 vascular access sites for angiographic catheter and inflow of circulatory support were required. An arterial inflow line equipped with a side arm was developed to enable single access to the right axillary artery to be used for the above purposes.

DOI： 10.1007/s11748-018-0905-2

PubMed
バスキュラーアクセスの造設部位が限られた患者における経カテーテル大動脈弁置換術のための循環サポートとカテーテル挿入用の分岐連結管を装着した動脈ライン(Arterial inflow line equipped with a side arm for circulatory support and catheter insertion during transcatheter aortic valve implantation for limited vascular access) Reviewed

Murakami Takashi, Sada Ryoji, Takahashi Yosuke, Nishimura Shinsuke, Mizutani Kazuki, Ito Asahiro, Iwata Shinichi, Yamada Tokuhiro, Yoshiyama Minoru, Shibata Toshihiko

General Thoracic and Cardiovascular Surgery 67 ( 3 ) 328 - 331 2019.03（ ISSN:1863-6705 ）

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Authorship：Lead author,　Corresponding author

症例は78歳男性で、重度の心不全のため当院へ搬送された。脳卒中とステージ4の慢性腎臓病の既往があり、経皮的冠動脈インターベンションの手術歴があった。心エコー検査で大動脈弁狭窄症を認め、大動脈弁口面積は0.68cm2、左室の拡張末期径は61mm、駆出率は20%であった。中等度の僧帽弁閉鎖不全も認めた。造影CT検査で左総頸動脈の起始部から内臓枝の分岐部にかけて重度のアテローム性動脈硬化を認め、また下行大動脈遠位部にアテローム性動脈硬化と石灰化を認めた。MRI検査で左内頸動脈と左椎骨動脈の閉塞と右総頸動脈の重度狭窄を認めた。開腹手術は困難と判断し、経カテーテル大動脈弁置換術を施行した。大動脈と左総頸動脈は重度のアテローム性動脈硬化のため塞栓リスクが高く、バスキュラーアクセスの作成は右腕に限られていた。全身麻酔下に人工心肺装置を接続し、右腕に右腋窩動脈送血のための動脈ラインを確保し、Y字連結管を使ってカテーテル挿入ポートを分岐連結した。脱血カニューレは右大腿静脈から右房に挿入した。カテーテル挿入ポートからSAPIEN XT生体弁を留置した。手術は成功し、術後16日目に転院となった。
Greater Nocturnal Blood Pressure Is Associated With Natriuretic Peptide Level in Aortic Stenosis With Preserved Ejection Fraction Reviewed

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Ishikawa Sera, Mizutani Kazuki, Izumiya Yasuhiro, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

一般社団法人日本循環器学会　CIRCULATION JOURNAL 83 ( 2 ) 447 - 451 2019.02（ ISSN:1346-9843 ）

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Background: Although careful monitoring of asymptomatic severe aortic stenosis (AS) is recommended to prevent missing the optimal timing of surgical or transcatheter aortic valve replacement, prophylactic treatment that could extend the asymptomatic period remains unknown. In a hypertensive population, high blood pressure (BP) measured at the doctor's office is known to be associated with B-type natriuretic peptide (BNP) level, a surrogate marker for symptomatic deterioration in AS. Little is known regarding the association between nocturnal BP variables and BNP in severe AS with preserved ejection fraction (EF). Methods and Results: The subjects consisted of 78 severe AS patients (mean age, 79±6 years) with preserved EF. Nocturnal BP was measured hourly using a home BP monitoring device. On multiple regression analysis, nocturnal mean systolic BP (SBP) remained independently associated with BNP after adjustment for age, sex, body mass index, estimated glomerular filtration rate, antihypertensive medication class, early diastolic mitral annular velocity, and left ventricular mass index (P=0.03), whereas diastolic BP (DBP) and variables of BP variability were not. Conclusions: Higher nocturnal SBP rather than DBP or indices of BP variability was independently associated with BNP in AS patients with preserved EF. Intervention for nocturnal SBP may therefore extend the asymptomatic period and improve prognosis. 

DOI： 10.1253/circj.CJ-18-0818

PubMed

CiNii Article
Greater Nocturnal Blood Pressure Is Associated With Natriuretic Peptide Level in Aortic Stenosis With Preserved Ejection Fraction. Reviewed

Soichiro Tamura, Shinichi Iwata, Asahiro Ito, Sera Ishikawa, Kazuki Mizutani, Yasuhiro Izumiya, Tokuhiro Yamada, Takashi Murakami, Toshihiko Shibata, Minoru Yoshiyama

Circulation journal : official journal of the Japanese Circulation Society 83 ( 2 ) 447 - 451 2019.01（ ISSN:1346-9843 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：Domestic journal

BACKGROUND: Although careful monitoring of asymptomatic severe aortic stenosis (AS) is recommended to prevent missing the optimal timing of surgical or transcatheter aortic valve replacement, prophylactic treatment that could extend the asymptomatic period remains unknown. In a hypertensive population, high blood pressure (BP) measured at the doctor's office is known to be associated with B-type natriuretic peptide (BNP) level, a surrogate marker for symptomatic deterioration in AS. Little is known regarding the association between nocturnal BP variables and BNP in severe AS with preserved ejection fraction (EF). Methods and Results: The subjects consisted of 78 severe AS patients (mean age, 79±6 years) with preserved EF. Nocturnal BP was measured hourly using a home BP monitoring device. On multiple regression analysis, nocturnal mean systolic BP (SBP) remained independently associated with BNP after adjustment for age, sex, body mass index, estimated glomerular filtration rate, antihypertensive medication class, early diastolic mitral annular velocity, and left ventricular mass index (P=0.03), whereas diastolic BP (DBP) and variables of BP variability were not. CONCLUSIONS: Higher nocturnal SBP rather than DBP or indices of BP variability was independently associated with BNP in AS patients with preserved EF. Intervention for nocturnal SBP may therefore extend the asymptomatic period and improve prognosis.

DOI： 10.1253/circj.CJ-18-0818

PubMed
Clinical usefulness of dobutamine stress echocardiography for the assessment of double-chambered right ventricle. Reviewed

Asahiro Ito, Shinichi Iwata, Shoichi Ehara, Yasuhiro Izumiya, Minoru Yoshiyama

European heart journal cardiovascular Imaging 20 ( 1 ) 120 - 120 2019.01（ ISSN:2047-2404 ）

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DOI： 10.1093/ehjci/jey158

PubMed
Clinical usefulness of dobutamine stress echocardiography for the assessment of double-chambered right ventricle Reviewed

Ito Asahiro, Iwata Shinichi, Ehara Shoichi, Izumiya Yasuhiro, Yoshiyama Minoru

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING 20 ( 1 ) 120 - 120 2019.01（ ISSN:2047-2404 ）

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DOI： 10.1093/ehjci/jey158

PubMed
左室駆出率の保たれている大動脈弁狭窄症において、夜間高血圧はナトリウム利尿ペプチド濃度と関連している(Greater Nocturnal Blood Pressure Is Associated With Natriuretic Peptide Level in Aortic Stenosis With Preserved Ejection Fraction) Reviewed

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Ishikawa Sera, Mizutani Kazuki, Izumiya Yasuhiro, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

(一社)日本循環器学会　Circulation Journal 83 ( 2 ) 447 - 451 2019.01（ ISSN:1346-9843 ）

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Publishing type：Research paper (scientific journal)

重症の大動脈弁狭窄症(AS)がみられるが左室駆出率は保たれている患者において、B型ナトリウム利尿ペプチド(BNP)の血漿中濃度と、夜間血圧の平均値や変動度との関連性について検討する横断研究を行った。当院に入院した上記患者を前向きに追跡した78名(女性44名、平均79±6歳)のデータを解析対象とした。家庭用血圧記録計を用い、入院初夜に1時間毎の夜間血圧を記録した。また入院時採血検体から血漿BNP濃度を測定した。多変量回帰分析の結果、夜間の平均収縮期血圧は独立してBNP濃度に関連していることが示され、各種調整因子(年齢、性別、BMI、推算糸球体濾過量、投薬されていた降圧剤のクラス、拡張早期僧帽弁輪運動速度、左室心筋重量指数)で調整した場合でもその関連性は依然として有意に認められた。一方、拡張期血圧や血圧変動度を表す変量にはそうしたBNP濃度との関連性はみられなかった。夜間収縮期血圧を指標として介入治療を行うことで無症候期間を延長し予後を向上させることができると考えられた。
左室駆出率の保たれている大動脈弁狭窄症において、夜間高血圧はナトリウム利尿ペプチド濃度と関連している(Greater Nocturnal Blood Pressure Is Associated With Natriuretic Peptide Level in Aortic Stenosis With Preserved Ejection Fraction) Reviewed

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Ishikawa Sera, Mizutani Kazuki, Izumiya Yasuhiro, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

Circulation Journal 83 ( 2 ) 447 - 451 2019.01（ ISSN:1346-9843 ）

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Authorship：Lead author,　Corresponding author

重症の大動脈弁狭窄症(AS)がみられるが左室駆出率は保たれている患者において、B型ナトリウム利尿ペプチド(BNP)の血漿中濃度と、夜間血圧の平均値や変動度との関連性について検討する横断研究を行った。当院に入院した上記患者を前向きに追跡した78名(女性44名、平均79±6歳)のデータを解析対象とした。家庭用血圧記録計を用い、入院初夜に1時間毎の夜間血圧を記録した。また入院時採血検体から血漿BNP濃度を測定した。多変量回帰分析の結果、夜間の平均収縮期血圧は独立してBNP濃度に関連していることが示され、各種調整因子(年齢、性別、BMI、推算糸球体濾過量、投薬されていた降圧剤のクラス、拡張早期僧帽弁輪運動速度、左室心筋重量指数)で調整した場合でもその関連性は依然として有意に認められた。一方、拡張期血圧や血圧変動度を表す変量にはそうしたBNP濃度との関連性はみられなかった。夜間収縮期血圧を指標として介入治療を行うことで無症候期間を延長し予後を向上させることができると考えられた。
Right ventricular enlargement predicts responsiveness to tolvaptan in congestive heart failure patients with reduced ejection fraction Reviewed

Nonin Shinichi, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kitada Ryoko, Kawai Yu, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

IJC HEART & VASCULATURE 21 69 - 73 2018.12

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Background: Tolvaptan is a vasopressin type 2 receptor antagonist used in heart failure (HF) with refractory diuretic resistance. However, since tolvaptan is also ineffective in some HF patients with reduced ejection fraction (HFrEF), the identification of responders is important. Methods: The study population consisted of 51 HFrEF patients who were administered tolvaptan (EF, 28 ± 7%). We defined responders as patients with a ≥50% increase in urine volume during the 24-hours after administration of tolvaptan. All patients underwent comprehensive transthoracic echocardiography before administration of tolvaptan. Patients were followed for 120 days to ascertain secondary events (cardiac death and rehospitalization for HF). Results: Multiple regression analysis indicated that right ventricular (RV) enlargement (defined as basal RV diameter > 41 mm and midlevel RV diameter > 35 mm, according to guidelines) remained a predictor of response after adjustment for age, sex, starting dosage of tolvaptan, and estimated glomerular filtration rate (odds ratio, 4.88; 95%-confidence interval, 1.26-18.9; P < 0.05), whereas left ventricular parameters and RV dysfunction were not. Kaplan-Meier curves indicated responsiveness to tolvaptan was associated with better prognosis among the overall population (P < 0.05); similar trends were observed among patients with RV dilatation (P = 0.056). Conclusions: These findings suggest that RV enlargement, which represents right-sided volume overload, elevated filling pressure, and diastolic dysfunction similar to that seen in constrictive pericarditis, predicts responsiveness to tolvaptan in patients with HFrEF. Moreover, administration of tolvaptan may have the potential to improve the reportedly poor prognosis for HFrEF patients with RV dilatation.

DOI： 10.1016/j.ijcha.2018.09.008

PubMed
Right ventricular enlargement predicts responsiveness to tolvaptan in congestive heart failure patients with reduced ejection fraction. Reviewed

Shinichi Nonin, Shinichi Iwata, Asahiro Ito, Soichiro Tamura, Ryoko Kitada, Yu Kawai, Sera Ishikawa, Atsushi Doi, Akihisa Hanatani, Minoru Yoshiyama

International journal of cardiology. Heart & vasculature 21 69 - 73 2018.12

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

Background: Tolvaptan is a vasopressin type 2 receptor antagonist used in heart failure (HF) with refractory diuretic resistance. However, since tolvaptan is also ineffective in some HF patients with reduced ejection fraction (HFrEF), the identification of responders is important. Methods: The study population consisted of 51 HFrEF patients who were administered tolvaptan (EF, 28 ± 7%). We defined responders as patients with a ≥50% increase in urine volume during the 24-hours after administration of tolvaptan. All patients underwent comprehensive transthoracic echocardiography before administration of tolvaptan. Patients were followed for 120 days to ascertain secondary events (cardiac death and rehospitalization for HF). Results: Multiple regression analysis indicated that right ventricular (RV) enlargement (defined as basal RV diameter > 41 mm and midlevel RV diameter > 35 mm, according to guidelines) remained a predictor of response after adjustment for age, sex, starting dosage of tolvaptan, and estimated glomerular filtration rate (odds ratio, 4.88; 95%-confidence interval, 1.26-18.9; P < 0.05), whereas left ventricular parameters and RV dysfunction were not. Kaplan-Meier curves indicated responsiveness to tolvaptan was associated with better prognosis among the overall population (P < 0.05); similar trends were observed among patients with RV dilatation (P = 0.056). Conclusions: These findings suggest that RV enlargement, which represents right-sided volume overload, elevated filling pressure, and diastolic dysfunction similar to that seen in constrictive pericarditis, predicts responsiveness to tolvaptan in patients with HFrEF. Moreover, administration of tolvaptan may have the potential to improve the reportedly poor prognosis for HFrEF patients with RV dilatation.

DOI： 10.1016/j.ijcha.2018.09.008

PubMed
Differences in Prevalence and Risk Factors of Silent Brain Infarction Between Patients With Paroxysmal and Persistent Nonvalvular Atrial Fibrillation Reviewed

Tamura Soichiro, Iwata Shinichi, Ishikawa Sera, Kitada Ryoda, Kawai Yu, Nonin Shinichi, Ito Asahiro, Doi Atsushi, Izumiya Yasuhiro, Yoshiyama Minoru

CIRCULATION 138 2018.11（ ISSN:0009-7322 ）

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Right Ventricular Enlargement Predicts Responsiveness to Tolvaptan in Congestive Heart Failure Patients With Reduced Ejection Fraction Reviewed

Nonin Shinichi, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kitada Ryoko, Kawai Yu, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

CIRCULATION 138 2018.11（ ISSN:0009-7322 ）

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Renal Impairment and CHA2DS2-VASc Score Are Associated With Silent Brain Infarction in Patients With Severe Aortic Stenosis. Reviewed

Tamura Soichiro, Iwata Shinichi, Kawai Yu, Ishikawa Sera, Ito Asahiro, Mizutani Kazuki, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

CIRCULATION 138 2018.11（ ISSN:0009-7322 ）

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Greater Nocturnal Blood Pressure is Associated With Natriuretic Peptide Level in Aortic Stenosis Patients With Preserved Ejection Fraction. Reviewed

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Ishikawa Sera, Mizutani Kazuki, Izumiya Yasuhiro, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

CIRCULATION 138 2018.11（ ISSN:0009-7322 ）

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駆出率を維持する心房細動患者において夜間血圧変動性は左房拡大と関連する(Greater nighttime blood pressure variability is associated with left atrial enlargement in atrial fibrillation patients with preserved ejection fraction) Reviewed

Norioka Naoki, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kawai Yu, Nonin Shinichi, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

Nature Publishing Group　Hypertension Research 41 ( 8 ) 614 - 621 2018.08（ ISSN:0916-9636 ）

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左室駆出率50%以上の心房細動患者140例を対象に、夜間血圧変動と左房容積の関連について検討した。夜間就寝時1時間ごとの血圧測定値の標準偏差を血圧変動性の指標とした。経胸壁心エコー図からbiplane Simpson変法により左房容積係数(LAVI)を算出した。年齢、性、降圧薬の種類、および左室心筋重量係数で補正した重回帰分析において、平均夜間収縮期/拡張期血圧およびその変動性は、LAVIと有意に関連した(いずれもP<0.01)。夜間血圧高値(≧120/70mmHg)でその変動性が大きい(SD≧12.2/7.9mmHg)患者のLAVIは46.6ml/m2で、夜間血圧とその変動性がともに基準値未満の患者の値(35.0ml/m2)に比べ有意に高かった(P<0.0001)。以上から、平均夜間血圧の上昇、および夜間血圧変動性の増大が左房拡大につながる可能性が示唆された。
The impact of MS with annular calcification for worsening heart failure just after TAVR Reviewed

Okai T., Mizutani K., Nakao M., Kajio K., Nishimura S., Ito A., Iwata S., Takahashi Y., Murakami T., Shibata T., Yoshiyama M.

EUROPEAN HEART JOURNAL 39 914 - 915 2018.08（ ISSN:0195-668X ）

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The impact of MS with annular calcification for worsening heart failure just after TAVR Reviewed

Okai T, Mizutani K, Nakao M, Kajio K, Nishimura S, Ito A, Iwata S, Takahashi Y, Murakami T, Shibata T, Yoshiyama M

EUROPEAN HEART JOURNAL 39 914 - 915 2018.08（ ISSN:0195-668X ）

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Greater nighttime blood pressure variability is associated with left atrial enlargement in atrial fibrillation patients with preserved ejection fraction Reviewed

Norioka Naoki, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kawai Yu, Nonin Shinichi, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

Nature Publishing Group　HYPERTENSION RESEARCH 41 ( 8 ) 614 - 621 2018.08（ ISSN:0916-9636 ）

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Left atrial enlargement is an independent risk factor for ischemic stroke in patients with atrial fibrillation. Little is known regarding the association between nighttime blood pressure variability and left atrial enlargement in patients with atrial fibrillation and preserved ejection fraction. The study population consisted of 140 consecutive patients with atrial fibrillation (mean age 64 ± 10 years) with preserved ejection fraction (≥50%). Nighttime blood pressure was measured at hourly intervals, using a home blood pressure monitoring device. Nighttime blood pressure variability was expressed as the standard deviation of all readings. Left atrial volume index was measured using the modified Simpson's biplane method with transthoracic echocardiography. Multiple regression analysis indicated that nighttime mean systolic/diastolic blood pressure and its variability remained independently associated with left atrial enlargement after adjustment for age, sex, anti-hypertensive medication class, and left ventricular mass index (P < 0.01). When patients were divided into four groups according to nighttime blood pressure and its variability, the group with higher nighttime blood pressure and its variability had significantly larger left atrial volume than the group with lower nighttime blood pressure and its variability (46.6 ml/m2 vs. 35.0 ml/m2, P < 0.0001). Higher nighttime blood pressure and its variability are associated with left atrial enlargement. The combination of nighttime blood pressure and its variability has additional predictive value for left atrial enlargement. Intensive intervention for these high-risk patients may avoid or delay progression of left atrial enlargement and reduce the risk of stroke.

DOI： 10.1038/s41440-018-0060-2

PubMed
駆出率を維持する心房細動患者において夜間血圧変動性は左房拡大と関連する(Greater nighttime blood pressure variability is associated with left atrial enlargement in atrial fibrillation patients with preserved ejection fraction)

Norioka Naoki, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kawai Yu, Nonin Shinichi, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

Hypertension Research 41 ( 8 ) 614 - 621 2018.08（ ISSN:0916-9636 ）

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左室駆出率50%以上の心房細動患者140例を対象に、夜間血圧変動と左房容積の関連について検討した。夜間就寝時1時間ごとの血圧測定値の標準偏差を血圧変動性の指標とした。経胸壁心エコー図からbiplane Simpson変法により左房容積係数(LAVI)を算出した。年齢、性、降圧薬の種類、および左室心筋重量係数で補正した重回帰分析において、平均夜間収縮期/拡張期血圧およびその変動性は、LAVIと有意に関連した(いずれもP<0.01)。夜間血圧高値(≧120/70mmHg)でその変動性が大きい(SD≧12.2/7.9mmHg)患者のLAVIは46.6ml/m2で、夜間血圧とその変動性がともに基準値未満の患者の値(35.0ml/m2)に比べ有意に高かった(P<0.0001)。以上から、平均夜間血圧の上昇、および夜間血圧変動性の増大が左房拡大につながる可能性が示唆された。
Greater nighttime blood pressure variability is associated with left atrial enlargement in atrial fibrillation patients with preserved ejection fraction. Reviewed

Naoki Norioka, Shinichi Iwata, Asahiro Ito, Soichiro Tamura, Yu Kawai, Shinichi Nonin, Sera Ishikawa, Atsushi Doi, Akihisa Hanatani, Minoru Yoshiyama

Hypertension research : official journal of the Japanese Society of Hypertension 41 ( 8 ) 614 - 621 2018.08（ ISSN:1348-4214 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

Left atrial enlargement is an independent risk factor for ischemic stroke in patients with atrial fibrillation. Little is known regarding the association between nighttime blood pressure variability and left atrial enlargement in patients with atrial fibrillation and preserved ejection fraction. The study population consisted of 140 consecutive patients with atrial fibrillation (mean age 64 ± 10 years) with preserved ejection fraction (≥50%). Nighttime blood pressure was measured at hourly intervals, using a home blood pressure monitoring device. Nighttime blood pressure variability was expressed as the standard deviation of all readings. Left atrial volume index was measured using the modified Simpson's biplane method with transthoracic echocardiography. Multiple regression analysis indicated that nighttime mean systolic/diastolic blood pressure and its variability remained independently associated with left atrial enlargement after adjustment for age, sex, anti-hypertensive medication class, and left ventricular mass index (P < 0.01). When patients were divided into four groups according to nighttime blood pressure and its variability, the group with higher nighttime blood pressure and its variability had significantly larger left atrial volume than the group with lower nighttime blood pressure and its variability (46.6 ml/m2 vs. 35.0 ml/m2, P < 0.0001). Higher nighttime blood pressure and its variability are associated with left atrial enlargement. The combination of nighttime blood pressure and its variability has additional predictive value for left atrial enlargement. Intensive intervention for these high-risk patients may avoid or delay progression of left atrial enlargement and reduce the risk of stroke.

DOI： 10.1038/s41440-018-0060-2

PubMed
The impact of MS with annular calcification for worsening heart failure just after TAVR Reviewed

Okai T, Mizutani K, Nakao M, Kajio K, Nishimura S, Ito A, Iwata S, Takahashi Y, Murakami T, Shibata T, Yoshiyama M

EUROPEAN HEART JOURNAL 39 914 - 915 2018.08（ ISSN:0195-668X ）

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THE IMPACT OF ANNULUS ECCENTRICITY AND OVER-SIZING VALVE DEPLOYMENT FOR LESS PARAVALVULAR LEAKAGE AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT Reviewed

Nakao Mana, Mizutani Kazuki, Okai Tsukasa, Yoshida Keiko, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 71 ( 11 ) 1144 - 1144 2018.03（ ISSN:0735-1097 ）

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DOI： 10.1016/S0735-1097(18)31685-1
THE IMPACT OF ANNULUS ECCENTRICITY AND OVER-SIZING VALVE DEPLOYMENT FOR LESS PARAVALVULAR LEAKAGE AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT Reviewed

Nakao Mana, Mizutani Kazuki, Okai Tsukasa, Yoshida Keiko, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 71 ( 11 ) 1144 - 1144 2018.03（ ISSN:0735-1097 ）

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DOI： 10.1016/S0735-1097(18)31685-1
Echocardiographic parameters predicting acute hemodynamically significant mitral regurgitation during transfemoral transcatheter aortic valve replacement Reviewed

Ito Asahiro, Iwata Shinichi, Mizutani Kazuki, Nonin Shinichi, Nishimura Shinsuke, Takahashi Yosuke, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

Blackwell Publishing Inc.　ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES 35 ( 3 ) 353 - 360 2018.03（ ISSN:0742-2822 ）

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BACKGROUND: Alteration in mitral valve morphology resulting from retrograde stiff wire entanglement sometimes causes hemodynamically significant acute mitral regurgitation (MR) during transfemoral transcatheter aortic valve replacement (TAVR). Little is known about the echocardiographic parameters related to hemodynamically significant acute MR. METHODS AND RESULTS: This study population consisted of 64 consecutive patients who underwent transfemoral TAVR. We defined hemodynamically significant acute MR as changes in the severity of MR with persistent hypotension (systolic blood pressure < 80-90 mm Hg or mean arterial pressure 30 mm Hg lower than baseline). Hemodynamically significant acute MR occurred in 5 cases (7.8%). Smaller left ventricular end-systolic diameter (LVDs), larger ratios of the coiled section of stiff wire tip to LVDs (wire-width/LVDs), and higher Wilkins score were significantly associated with hemodynamically significant acute MR (P < .05), whereas the parameters of functional MR (annular area, anterior-posterior diameter, tenting area, and coaptation length) were not. Moreover, when patients were divided into 4 groups according to wire-width/LVDs and Wilkins score, the group with the larger wire-width/LVDs and higher Wilkins score improved prediction rates (P < .05). CONCLUSIONS: Small left ventricle or wire oversizing and calcific mitral apparatus were predictive of hemodynamically significant acute MR. These findings are important for risk stratification, and careful monitoring using intraoperative transesophageal echocardiography may improve the safety in this population.

DOI： 10.1111/echo.13792

PubMed
Echocardiographic parameters predicting acute hemodynamically significant mitral regurgitation during transfemoral transcatheter aortic valve replacement. Reviewed

Asahiro Ito, Shinichi Iwata, Kazuki Mizutani, Shinichi Nonin, Shinsuke Nishimura, Yosuke Takahashi, Tokuhiro Yamada, Takashi Murakami, Toshihiko Shibata, Minoru Yoshiyama

Echocardiography (Mount Kisco, N.Y.) 35 ( 3 ) 353 - 360 2018.03（ ISSN:1540-8175 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

BACKGROUND: Alteration in mitral valve morphology resulting from retrograde stiff wire entanglement sometimes causes hemodynamically significant acute mitral regurgitation (MR) during transfemoral transcatheter aortic valve replacement (TAVR). Little is known about the echocardiographic parameters related to hemodynamically significant acute MR. METHODS AND RESULTS: This study population consisted of 64 consecutive patients who underwent transfemoral TAVR. We defined hemodynamically significant acute MR as changes in the severity of MR with persistent hypotension (systolic blood pressure < 80-90 mm Hg or mean arterial pressure 30 mm Hg lower than baseline). Hemodynamically significant acute MR occurred in 5 cases (7.8%). Smaller left ventricular end-systolic diameter (LVDs), larger ratios of the coiled section of stiff wire tip to LVDs (wire-width/LVDs), and higher Wilkins score were significantly associated with hemodynamically significant acute MR (P < .05), whereas the parameters of functional MR (annular area, anterior-posterior diameter, tenting area, and coaptation length) were not. Moreover, when patients were divided into 4 groups according to wire-width/LVDs and Wilkins score, the group with the larger wire-width/LVDs and higher Wilkins score improved prediction rates (P < .05). CONCLUSIONS: Small left ventricle or wire oversizing and calcific mitral apparatus were predictive of hemodynamically significant acute MR. These findings are important for risk stratification, and careful monitoring using intraoperative transesophageal echocardiography may improve the safety in this population.

DOI： 10.1111/echo.13792

PubMed
Safety and Feasibility Report of Investigational Therapy With Interleukin-11 Against Acute Myocardial Infarction Reviewed

Maeda Makiko, Nakagawa Masaki, Owada Yasuko, Izumi Yasukatsu, Nonin Shinichi, Sugioka Kenichi, Nakatani Daisaku, Iwata Shinichi, Mizutani Kazuki, Nishimura Satoshi, Ito Asahiro, Fujita Suwako, Daimon Takashi, Sawa Yoshiki, Asakura Masanori, Fujio Yasushi, Yoshiyama Minoru

CIRCULATION 136 2017.11（ ISSN:0009-7322 ）

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DOI： 10.1007/s00380-015-0788-4
Relationship between tissue Doppler measurements of left ventricular diastolic function and silent brain infarction in patients with non-valvular atrial fibrillation. Reviewed

Sera Ishikawa, Kenichi Sugioka, Shinichi Sakamoto, Suwako Fujita, Asahiro Ito, Naoki Norioka, Shinichi Iwata, Masashi Nakagawa, Masahiko Takagi, Yukio Miki, Makiko Ueda, Minoru Yoshiyama

European heart journal cardiovascular Imaging 18 ( 11 ) 1245 - 1252 2017.11（ ISSN:2047-2404 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

Aims: Left ventricular (LV) diastolic function assessed by tissue Doppler imaging (TDI) is reported to be associated with left atrial (LA) blood stasis in patients with non-valvular atrial fibrillation (AF). This study aimed to evaluate the relationship of diastolic TDI parameters with silent brain infarction (SBI) on brain magnetic resonance imaging (MRI), and in turn the risks of subsequent stroke or dementia, in non-valvular AF patients. Methods and results: The study population consisted of 171 neurologically asymptomatic patients with non-valvular AF who underwent transoesophageal echocardiography (TOE) (128 men; mean age, 63 ± 11 years). We measured diastolic TDI parameters by transthoracic echocardiography, and also screened for SBI employing brain MRI. Early transmitral flow velocity (E) and mitral annular velocity by TDI (e') were measured, and E/e' ratios were calculated. An increased tertile of the E/e' ratio was significantly related to high prevalences of LA abnormalities detected by TOE (32% vs. 12% vs. 9%; P =0.002) and SBI on brain MRI (46% vs. 23% vs. 14%; P < 0.001). In multivariate logistic regression analyses after adjustment for age, hypertension, chronic kidney disease, and CHA2DS2-VASc score ≥2, the E/e' ratio ≥12.4 was found to be an independent predictor of the presence of SBI (OR 3.98, 95% CI 1.74-9.07; P = 0.001). Conclusions: Impaired LV diastolic function evaluated by increased E/e' ratio was closely associated with the presence of SBI independent of CHA2DS2-VASc score. TDI measurements are non-invasive and useful for risk stratification of the early stage of cerebral damages in patients with non-valvular AF.

DOI： 10.1093/ehjci/jew220

PubMed
Relationship between tissue Doppler measurements of left ventricular diastolic function and silent brain infarction in patients with non-valvular atrial fibrillation Reviewed

Ishikawa Sera, Sugioka Kenichi, Sakamoto Shinichi, Fujita Suwako, Ito Asahiro, Norioka Naoki, Iwata Shinichi, Nakagawa Masashi, Takagi Masahiko, Miki Yukio, Ueda Makiko, Yoshiyama Minoru

OXFORD UNIV PRESS　EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING 18 ( 11 ) 1245 - 1252 2017.11（ ISSN:2047-2404 ）

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Publishing type：Research paper (scientific journal)

Aims: Left ventricular (LV) diastolic function assessed by tissue Doppler imaging (TDI) is reported to be associated with left atrial (LA) blood stasis in patients with non-valvular atrial fibrillation (AF). This study aimed to evaluate the relationship of diastolic TDI parameters with silent brain infarction (SBI) on brain magnetic resonance imaging (MRI), and in turn the risks of subsequent stroke or dementia, in non-valvular AF patients. Methods and results: The study population consisted of 171 neurologically asymptomatic patients with non-valvular AF who underwent transoesophageal echocardiography (TOE) (128 men; mean age, 63 ± 11 years). We measured diastolic TDI parameters by transthoracic echocardiography, and also screened for SBI employing brain MRI. Early transmitral flow velocity (E) and mitral annular velocity by TDI (e') were measured, and E/e' ratios were calculated. An increased tertile of the E/e' ratio was significantly related to high prevalences of LA abnormalities detected by TOE (32% vs. 12% vs. 9%; P =0.002) and SBI on brain MRI (46% vs. 23% vs. 14%; P < 0.001). In multivariate logistic regression analyses after adjustment for age, hypertension, chronic kidney disease, and CHA2DS2-VASc score ≥2, the E/e' ratio ≥12.4 was found to be an independent predictor of the presence of SBI (OR 3.98, 95% CI 1.74-9.07; P = 0.001). Conclusions: Impaired LV diastolic function evaluated by increased E/e' ratio was closely associated with the presence of SBI independent of CHA2DS2-VASc score. TDI measurements are non-invasive and useful for risk stratification of the early stage of cerebral damages in patients with non-valvular AF.

DOI： 10.1093/ehjci/jew220

PubMed
Safety and Efficacy of Simultaneous Biplane Mode of 3-Dimensional Transesophageal Echocardiography-Guided Antegrade Multiple-Inflation Balloon Aortic Valvuloplasty in Patients With Severe Aortic Stenosis Reviewed

Mizutani Kazuki, Hara Masahiko, Ishikawa Hirotoshi, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Sugioka Kenichi, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

一般社団法人日本循環器学会　CIRCULATION JOURNAL 81 ( 5 ) 748 - 754 2017.05（ ISSN:1346-9843 ）

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Background:Balloon aortic valvuloplasty (BAV) is resurging as a bridge treatment in patients with severe aortic stenosis (AS) with a dissemination of transcatheter aortic valve implantation. However, the significantly high periprocedural mortality and complication rates still limit the indications of BAV. Further efforts are needed to improve the safety and efficacy of BAV.Methods and Results:We retrospectively investigated the safety and efficacy of simultaneous biplane mode of 3-dimensional transesophageal echocardiography (biplane-TEE) guided antegrade transseptal multiple-inflation BAV, with gradual upsizing of the balloon, by enrolling 20 consecutive AS patients who underwent BAV. The median age was 83 years, and there were 6 male patients (30.0%). The clinical frailty scale was 4, and the Society of Thoracic Surgeon score was 14.5%. The balloon was inflated at a median of 18 times, which improved the mean aortic valve pressure gradient from 43.0 to 15.2 mmHg (P<0.001). We safely performed BAV in all patients, without periprocedural death or symptomatic stroke, although asymptomatic stroke was detected in 8 patients (42.1%) on diffusion-weighted magnetic resonance imaging. Kaplan-Meier estimates showed that the survival rate was 84.0% and cardiovascular death-free survival was 88.9% at 1-year.Conclusions:Biplane-TEE guided antegrade multiple-inflation BAV might have the potential to improve periprocedural survival without increasing complications, compared with conventional retrograde BAV in patients with severe AS.

DOI： 10.1253/circj.CJ-16-0909

PubMed

CiNii Article
前回の経中隔僧帽弁手術後の僧帽弁周囲漏出に対する経心尖部からの経カテーテル閉鎖術(Transcatheter closure through transapical access for mitral paravalvular leak after previous trans-septal mitral operation) Reviewed

Murakami Takashi, Suehiro Yasuo, Nishimura Shinsuke, Sugioka Kenichi, Iwata Shinichi, Ito Asahiro, Sohgawa Etsuji, Mizutani Kazuki, Yoshiyama Minoru, Shibata Toshihiko

シュプリンガー・ジャパン(株)　General Thoracic and Cardiovascular Surgery 65 ( 5 ) 289 - 292 2017.05（ ISSN:1863-6705 ）

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Publishing type：Research paper (scientific journal)

症例は74歳男性で、心不全治療のため当院に転院となった。来院時に安静時呼吸困難が認められ、陽圧換気を行った。8年前に僧帽弁置換術を受けており、2ヵ月前には人工弁心内膜炎のため経心房中隔アプローチによる僧帽弁再置換術を受けていた。経食道心エコー(TEE)で肺高血圧症を伴う重度の弁周囲漏出が認められた。病歴から、心房中隔の穿通は通常の順行性経中隔アプローチでは困難であると考えられたため、左室心尖部を介して経カテーテル弁周囲漏出閉鎖術を行った。術後CTでは、欠損部がAMPLATZER Vascular Plugsで充填されているのが確認された。6ヵ月後のフォローアップ時に心不全の臨床症状や溶血の徴候はみられなかった。
Transcatheter closure through transapical access for mitral paravalvular leak after previous trans-septal mitral operation Reviewed

Murakami Takashi, Suehiro Yasuo, Nishimura Shinsuke, Sugioka Kenichi, Iwata Shinichi, Ito Asahiro, Sohgawa Etsuji, Mizutani Kazuki, Yoshiyama Minoru, Shibata Toshihiko

Springer Tokyo　GENERAL THORACIC AND CARDIOVASCULAR SURGERY 65 ( 5 ) 289 - 292 2017.05（ ISSN:1863-6705 ）

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Because paravalvular leak after mitral valve replacement in highly morbid patients is a troublesome issue, there has been a growing interest in less invasive procedures. We conducted transcatheter paravalvular leak closure of a mitral valve prosthesis through left ventricular apical access. The patient had undergone redo mitral valve replacement through a transatrial septal approach 2 months prior to the procedure; thus, penetration of the atrial septum was considered to be difficult through the ordinary antegrade trans-septal approach. Transapical access for the mitral paravalvular leak was conducted using two AMPLATZER Vascular Plugs (St. Jude Medical, St. Paul, MN), with a route directed straight to the defect. This approach is an alternative technique for transcatheter paravalvular leak closure. This is the first case report of transapical access for transcatheter paravalvular leak closure in Japan.

DOI： 10.1007/s11748-016-0644-1

PubMed
前回の経中隔僧帽弁手術後の僧帽弁周囲漏出に対する経心尖部からの経カテーテル閉鎖術(Transcatheter closure through transapical access for mitral paravalvular leak after previous trans-septal mitral operation) Reviewed

Murakami Takashi, Suehiro Yasuo, Nishimura Shinsuke, Sugioka Kenichi, Iwata Shinichi, Ito Asahiro, Sohgawa Etsuji, Mizutani Kazuki, Yoshiyama Minoru, Shibata Toshihiko

General Thoracic and Cardiovascular Surgery 65 ( 5 ) 289 - 292 2017.05（ ISSN:1863-6705 ）

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Authorship：Lead author,　Corresponding author

症例は74歳男性で、心不全治療のため当院に転院となった。来院時に安静時呼吸困難が認められ、陽圧換気を行った。8年前に僧帽弁置換術を受けており、2ヵ月前には人工弁心内膜炎のため経心房中隔アプローチによる僧帽弁再置換術を受けていた。経食道心エコー(TEE)で肺高血圧症を伴う重度の弁周囲漏出が認められた。病歴から、心房中隔の穿通は通常の順行性経中隔アプローチでは困難であると考えられたため、左室心尖部を介して経カテーテル弁周囲漏出閉鎖術を行った。術後CTでは、欠損部がAMPLATZER Vascular Plugsで充填されているのが確認された。6ヵ月後のフォローアップ時に心不全の臨床症状や溶血の徴候はみられなかった。
Transcatheter closure through transapical access for mitral paravalvular leak after previous trans-septal mitral operation. Reviewed

Takashi Murakami, Yasuo Suehiro, Shinsuke Nishimura, Kenichi Sugioka, Shinichi Iwata, Asahiro Ito, Etsuji Sohgawa, Kazuki Mizutani, Minoru Yoshiyama, Toshihiko Shibata

General thoracic and cardiovascular surgery 65 ( 5 ) 289 - 292 2017.05（ ISSN:1863-6713 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：Domestic journal

Because paravalvular leak after mitral valve replacement in highly morbid patients is a troublesome issue, there has been a growing interest in less invasive procedures. We conducted transcatheter paravalvular leak closure of a mitral valve prosthesis through left ventricular apical access. The patient had undergone redo mitral valve replacement through a transatrial septal approach 2 months prior to the procedure; thus, penetration of the atrial septum was considered to be difficult through the ordinary antegrade trans-septal approach. Transapical access for the mitral paravalvular leak was conducted using two AMPLATZER Vascular Plugs (St. Jude Medical, St. Paul, MN), with a route directed straight to the defect. This approach is an alternative technique for transcatheter paravalvular leak closure. This is the first case report of transapical access for transcatheter paravalvular leak closure in Japan.

DOI： 10.1007/s11748-016-0644-1

PubMed
Safety and Efficacy of Simultaneous Biplane Mode of 3-Dimensional Transesophageal Echocardiography-Guided Antegrade Multiple-Inflation Balloon Aortic Valvuloplasty in Patients With Severe Aortic Stenosis. Reviewed

Kazuki Mizutani, Masahiko Hara, Hirotoshi Ishikawa, Shinsuke Nishimura, Asahiro Ito, Shinichi Iwata, Yosuke Takahashi, Kenichi Sugioka, Takashi Murakami, Toshihiko Shibata, Minoru Yoshiyama

Circulation journal : official journal of the Japanese Circulation Society 81 ( 5 ) 748 - 754 2017.04（ ISSN:1346-9843 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：Domestic journal

BACKGROUND: Balloon aortic valvuloplasty (BAV) is resurging as a bridge treatment in patients with severe aortic stenosis (AS) with a dissemination of transcatheter aortic valve implantation. However, the significantly high periprocedural mortality and complication rates still limit the indications of BAV. Further efforts are needed to improve the safety and efficacy of BAV.Methods and Results:We retrospectively investigated the safety and efficacy of simultaneous biplane mode of 3-dimensional transesophageal echocardiography (biplane-TEE) guided antegrade transseptal multiple-inflation BAV, with gradual upsizing of the balloon, by enrolling 20 consecutive AS patients who underwent BAV. The median age was 83 years, and there were 6 male patients (30.0%). The clinical frailty scale was 4, and the Society of Thoracic Surgeon score was 14.5%. The balloon was inflated at a median of 18 times, which improved the mean aortic valve pressure gradient from 43.0 to 15.2 mmHg (P<0.001). We safely performed BAV in all patients, without periprocedural death or symptomatic stroke, although asymptomatic stroke was detected in 8 patients (42.1%) on diffusion-weighted magnetic resonance imaging. Kaplan-Meier estimates showed that the survival rate was 84.0% and cardiovascular death-free survival was 88.9% at 1-year. CONCLUSIONS: Biplane-TEE guided antegrade multiple-inflation BAV might have the potential to improve periprocedural survival without increasing complications, compared with conventional retrograde BAV in patients with severe AS.

DOI： 10.1253/circj.CJ-16-0909

PubMed
重症大動脈弁狭窄症患者における同時2断面表示による3次元経食道心エコーのガイド下に段階的に弁拡張する順行性大動脈弁バルーン形成術の安全性と有効性(Safety and Efficacy of Simultaneous Biplane Mode of 3-Dimensional Transesophageal Echocardiography-Guided Antegrade Multiple-Inflation Balloon Aortic Valvuloplasty in Patients With Severe Aortic Stenosis)

Mizutani Kazuki, Hara Masahiko, Ishikawa Hirotoshi, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Sugioka Kenichi, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

Circulation Journal 81 ( 5 ) 748 - 754 2017.04（ ISSN:1346-9843 ）

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大動脈弁バルーン形成術(BAV)を施行した重症大動脈弁狭窄症患者20例[男性6例、女性14例、年齢中央値83歳(77〜87歳)]を対象に、2断面を同時表示する3次元経食道心エコーのガイド下に段階的な弁拡張が可能なイノウエバルーンを使った順行性アプローチによるBAV術の安全性と有効性を検討した。患者の90%が高血圧症を有し、半数以上の患者はNYHA心機能分類がIII度以上であった。臨床フレイルスケールは4で、STS-PROMの推定死亡リスクは14.5%であった。大動脈弁圧較差は術前の43.0mmHgから術後15.2mmHg、大動脈弁弁口面積(Gorlin法)は0.61cm2から1.19cm2と有意に改善した(いずれもP<0.001)。周術期死亡または症候性脳梗塞等の重大な合併症はなかったが、MRI拡散強調画像により無症候性脳卒中が8例(42.1%)で検出された。Kaplan-Meier曲線による1年生存率は84.0%で、心血管死回避率は88.9%であった。
重症大動脈弁狭窄症患者における同時2断面表示による3次元経食道心エコーのガイド下に段階的に弁拡張する順行性大動脈弁バルーン形成術の安全性と有効性(Safety and Efficacy of Simultaneous Biplane Mode of 3-Dimensional Transesophageal Echocardiography-Guided Antegrade Multiple-Inflation Balloon Aortic Valvuloplasty in Patients With Severe Aortic Stenosis) Reviewed

Mizutani Kazuki, Hara Masahiko, Ishikawa Hirotoshi, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Sugioka Kenichi, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

(一社)日本循環器学会　Circulation Journal 81 ( 5 ) 748 - 754 2017.04（ ISSN:1346-9843 ）

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Publishing type：Research paper (scientific journal)

大動脈弁バルーン形成術(BAV)を施行した重症大動脈弁狭窄症患者20例[男性6例、女性14例、年齢中央値83歳(77〜87歳)]を対象に、2断面を同時表示する3次元経食道心エコーのガイド下に段階的な弁拡張が可能なイノウエバルーンを使った順行性アプローチによるBAV術の安全性と有効性を検討した。患者の90%が高血圧症を有し、半数以上の患者はNYHA心機能分類がIII度以上であった。臨床フレイルスケールは4で、STS-PROMの推定死亡リスクは14.5%であった。大動脈弁圧較差は術前の43.0mmHgから術後15.2mmHg、大動脈弁弁口面積(Gorlin法)は0.61cm2から1.19cm2と有意に改善した(いずれもP<0.001)。周術期死亡または症候性脳梗塞等の重大な合併症はなかったが、MRI拡散強調画像により無症候性脳卒中が8例(42.1%)で検出された。Kaplan-Meier曲線による1年生存率は84.0%で、心血管死回避率は88.9%であった。
Plaque surface irregularity and calcification length within carotid plaque predict secondary events in patients with coronary artery disease Reviewed

Nonin Shinichi, Iwata Shinichi, Sugioka Kenichi, Fujita Suwako, Norioka Naoki, Ito Asahiro, Nakagawa Masashi, Yoshiyama Minoru

ELSEVIER IRELAND LTD　ATHEROSCLEROSIS 256 29 - 34 2017.01（ ISSN:0021-9150 ）

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Publishing type：Research paper (scientific journal)

BACKGROUND AND AIMS: Although comprehensive risk factor modification is recommended, a uniform management strategy does not necessarily prevent secondary events in patients with coronary artery disease (CAD). Therefore, identification of high-risk patients who may benefit from more intensive interventions may improve prognosis. Carotid ultrasound can reliably identify systemic atherosclerosis, and carotid plaque and intima-media thickness (IMT) are known independent risk factors for CAD. However, it is unclear whether findings on carotid ultrasound can improve prediction of secondary CAD events. METHODS: The study population comprised 146 consecutive patients with CAD (mean age, 66 ± 9 years; 126 with angina pectoris, 20 with acute myocardial infarction). IMT, plaque score, plaque area, plaque surface irregularity, and calcification length (calculated by summing the calcified lesions within each plaque accompanied by acoustic shadow) were measured at baseline. Patients were followed for 10 years to ascertain secondary CAD events defined as hard major adverse cardiovascular events (MACE; cardiac death and acute myocardial infarction) and as total MACE (hard MACE and angina pectoris with coronary revascularization). RESULTS: Multiple regression analysis demonstrated that calcification length (p < 0.05) and plaque surface irregularity (p < 0.01) remained independently associated with total MACE after adjustment for age, sex, diabetes mellitus, dyslipidemia, hypertension, chronic kidney disease, smoking, and multivessel CAD. CONCLUSIONS: These findings suggest that the combination of calcification length and plaque surface irregularity has additional value beyond traditional risk classification. Intensive intervention for these high-risk patients may avoid or delay progression of atherosclerosis towards secondary CAD events.

DOI： 10.1016/j.atherosclerosis.2016.11.008

PubMed
Plaque surface irregularity and calcification length within carotid plaque predict secondary events in patients with coronary artery disease. Reviewed

Shinichi Nonin, Shinichi Iwata, Kenichi Sugioka, Suwako Fujita, Naoki Norioka, Asahiro Ito, Masashi Nakagawa, Minoru Yoshiyama

Atherosclerosis 256 29 - 34 2017.01（ ISSN:0021-9150 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

BACKGROUND AND AIMS: Although comprehensive risk factor modification is recommended, a uniform management strategy does not necessarily prevent secondary events in patients with coronary artery disease (CAD). Therefore, identification of high-risk patients who may benefit from more intensive interventions may improve prognosis. Carotid ultrasound can reliably identify systemic atherosclerosis, and carotid plaque and intima-media thickness (IMT) are known independent risk factors for CAD. However, it is unclear whether findings on carotid ultrasound can improve prediction of secondary CAD events. METHODS: The study population comprised 146 consecutive patients with CAD (mean age, 66 ± 9 years; 126 with angina pectoris, 20 with acute myocardial infarction). IMT, plaque score, plaque area, plaque surface irregularity, and calcification length (calculated by summing the calcified lesions within each plaque accompanied by acoustic shadow) were measured at baseline. Patients were followed for 10 years to ascertain secondary CAD events defined as hard major adverse cardiovascular events (MACE; cardiac death and acute myocardial infarction) and as total MACE (hard MACE and angina pectoris with coronary revascularization). RESULTS: Multiple regression analysis demonstrated that calcification length (p < 0.05) and plaque surface irregularity (p < 0.01) remained independently associated with total MACE after adjustment for age, sex, diabetes mellitus, dyslipidemia, hypertension, chronic kidney disease, smoking, and multivessel CAD. CONCLUSIONS: These findings suggest that the combination of calcification length and plaque surface irregularity has additional value beyond traditional risk classification. Intensive intervention for these high-risk patients may avoid or delay progression of atherosclerosis towards secondary CAD events.

DOI： 10.1016/j.atherosclerosis.2016.11.008

PubMed
急性心筋梗塞に対してインターロイキン-11による調査的治療を行った4例(Four cases of investigational therapy with interleukin-11 against acute myocardial infarction) Reviewed

Nakagawa Masashi, Owada Yasuko, Izumi Yasukatsu, Nonin Shinichi, Sugioka Kenichi, Nakatani Daisaku, Iwata Shinichi, Mizutani Kazuki, Nishimura Satoshi, Ito Asahiro, Fujita Suwako, Daimon Takashi, Sawa Yoshiki, Asakura Masanori, Maeda Makiko, Fujio Yasushi, Yoshiyama Minoru

シュプリンガー・ジャパン(株)　Heart and Vessels 31 ( 9 ) 1574 - 1578 2016.09（ ISSN:0910-8327 ）

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症例1は72歳男性で、前胸部圧迫感が8時間持続した。冠動脈造影(CAG)で左冠動脈前下行枝(LAD)#6の完全閉塞が認められた。TIMI分類グレード0が確認された直後から遺伝子組換えインターロイキン-11(rhIL-11)(6μg/kg)を開始した。経皮的冠動脈インターベンション(PCI)で奏効が得られた。ELISAによるrhIL-11の最大血中濃度は6ng/mLであった。症例2は75歳男性で、2年前から労作時胸部不快感があり、間欠性の前胸部圧迫感が12時間持続した。CAGにてLAD#6の完全閉塞、左回旋枝(LCx)の90%閉塞、右冠状動脈(RCA)とLCxからLADへの側副血行路が認められた。CAG直後にrhIL-11(6μg/kg)を開始した。PCIにより奏効が得られた。rhIL-11の最大血中濃度は6ng/mLであった。この症例は慢性期にLFEVの改善がみられなかった。症例3は72歳男性で、4年前から高血圧症であり、冷汗を伴う背部痛が4時間持続した。CAGにてTIMI分類グレード0のLAD#6の完全閉塞が認められた。CAG直後からrhIL-11(25μg/kg)を開始した。CAG後にPCIを施行し、TIMI分類グレード3が得られた。rhIL-11の最大血中濃度は48ng/mLであった。症例4は69歳男性で、1ヵ月前から労作時胸部圧迫感があり、胸部圧迫感が5時間持続した。CAGにてLAD#6の完全閉塞とRCA#2の90%狭窄が認められた。CAG直後からrhIL-11(25μg/kg)を開始し、PCIで奏効が得られた。rhIL-11の最大血中濃度は24ng/mLであった。4例とも心不全の症状を含む薬物有害反応は観察されず退院となった。
Four cases of investigational therapy with interleukin-11 against acute myocardial infarction Reviewed

Nakagawa Masashi, Owada Yasuko, Izumi Yasukatsu, Nonin Shinichi, Sugioka Kenichi, Nakatani Daisaku, Iwata Shinichi, Mizutani Kazuki, Nishimura Satoshi, Ito Asahiro, Fujita Suwako, Daimon Takashi, Sawa Yoshiki, Asakura Masanori, Maeda Makiko, Fujio Yasushi, Yoshiyama Minoru

HEART AND VESSELS 31 ( 9 ) 1574 - 1578 2016.09（ ISSN:0910-8327 ）

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DOI： 10.1007/s00380-015-0788-4
Four cases of investigational therapy with interleukin-11 against acute myocardial infarction. Reviewed

Masashi Nakagawa, Yasuko Owada, Yasukatsu Izumi, Shinichi Nonin, Kenichi Sugioka, Daisaku Nakatani, Shinichi Iwata, Kazuki Mizutani, Satoshi Nishimura, Asahiro Ito, Suwako Fujita, Takashi Daimon, Yoshiki Sawa, Masanori Asakura, Makiko Maeda, Yasushi Fujio, Minoru Yoshiyama

Heart and vessels 31 ( 9 ) 1574 - 8 2016.09

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Publishing type：Research paper (scientific journal) International / domestic magazine：Domestic journal

We describe four cases of the patients with ST-elevation myocardial infarction (STEMI) that were treated with interleukin-11 (IL-11), a cardioprotective cytokine. Recombinant human IL-11 (rhIL-11), was intravenously administered to two cases at low dose (6 µg/kg) and to two at high dose (25 µg/kg). The cytokine administration started just after the coronary occlusion was confirmed by coronary angiography (CAG), taking 3 h. Following CAG, percutaneous coronary intervention (PCI) was performed as a standard therapy. No serious adverse drug reactions were observed. All the cases left the hospital without the symptom of heart failure. We discuss the possibility of the clinical use of rhIL-11 as an adjunct therapy to PCI for the STEMI patients.

DOI： 10.1007/s00380-015-0788-4

PubMed
急性心筋梗塞に対してインターロイキン-11による調査的治療を行った4例(Four cases of investigational therapy with interleukin-11 against acute myocardial infarction) Reviewed

Nakagawa Masashi, Owada Yasuko, Izumi Yasukatsu, Nonin Shinichi, Sugioka Kenichi, Nakatani Daisaku, Iwata Shinichi, Mizutani Kazuki, Nishimura Satoshi, Ito Asahiro, Fujita Suwako, Daimon Takashi, Sawa Yoshiki, Asakura Masanori, Maeda Makiko, Fujio Yasushi, Yoshiyama Minoru

Heart and Vessels 31 ( 9 ) 1574 - 1578 2016.09（ ISSN:0910-8327 ）

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Authorship：Lead author,　Corresponding author

症例1は72歳男性で、前胸部圧迫感が8時間持続した。冠動脈造影(CAG)で左冠動脈前下行枝(LAD)#6の完全閉塞が認められた。TIMI分類グレード0が確認された直後から遺伝子組換えインターロイキン-11(rhIL-11)(6μg/kg)を開始した。経皮的冠動脈インターベンション(PCI)で奏効が得られた。ELISAによるrhIL-11の最大血中濃度は6ng/mLであった。症例2は75歳男性で、2年前から労作時胸部不快感があり、間欠性の前胸部圧迫感が12時間持続した。CAGにてLAD#6の完全閉塞、左回旋枝(LCx)の90%閉塞、右冠状動脈(RCA)とLCxからLADへの側副血行路が認められた。CAG直後にrhIL-11(6μg/kg)を開始した。PCIにより奏効が得られた。rhIL-11の最大血中濃度は6ng/mLであった。この症例は慢性期にLFEVの改善がみられなかった。症例3は72歳男性で、4年前から高血圧症であり、冷汗を伴う背部痛が4時間持続した。CAGにてTIMI分類グレード0のLAD#6の完全閉塞が認められた。CAG直後からrhIL-11(25μg/kg)を開始した。CAG後にPCIを施行し、TIMI分類グレード3が得られた。rhIL-11の最大血中濃度は48ng/mLであった。症例4は69歳男性で、1ヵ月前から労作時胸部圧迫感があり、胸部圧迫感が5時間持続した。CAGにてLAD#6の完全閉塞とRCA#2の90%狭窄が認められた。CAG直後からrhIL-11(25μg/kg)を開始し、PCIで奏効が得られた。rhIL-11の最大血中濃度は24ng/mLであった。4例とも心不全の症状を含む薬物有害反応は観察されず退院となった。
Remarkably Intense Emission from Ruthenium(II) Complexes with Multiple Borane Centers Reviewed

Nakagawa Atsushi, Sakuda Eri, Ito Akitaka, Kitamura Noboru

INORGANIC CHEMISTRY 54 ( 21 ) 10287 - 10295 2015.11（ ISSN:0020-1669 ）

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Publishing type：Research paper (scientific journal)

DOI： 10.1021/acs.inorgchem.5b01626
Aortic arch atherosclerosis in patients with severe aortic stenosis can be argued by greater day-by-day blood pressure variability Reviewed

Iwata Shinichi, Sugioka Kenichi, Fujita Suwako, Ito Asahiro, Matsumura Yoshiki, Hanatani Akihisa, Takagi Masahiko, Di Tullio Marco R., Homma Shunichi, Yoshiyama Minoru

ELSEVIER IRELAND LTD　ATHEROSCLEROSIS 241 ( 1 ) 42 - 47 2015.07（ ISSN:0021-9150 ）

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Publishing type：Research paper (scientific journal)

BACKGROUND AND PURPOSE: Although it is well known that the prevalence of aortic arch plaques, one of the risk factors for ischemic stroke, is high in patients with severe aortic stenosis, the underlying mechanisms are not well understood. Increased day-by-day blood pressure (BP) variability is also known to be associated with stroke; however, little is known on the association between day-by-bay BP variability and aortic arch atherosclerosis in patients with aortic stenosis. Our objective was to clarify the association between day-by-day BP variables (average values and variability) and aortic arch atherosclerosis in patients with severe aortic stenosis. METHODS: The study population consisted of 104 consecutive patients (mean age 75 ± 8 years) with severe aortic stenosis who were scheduled for aortic valve replacement. BP was measured in the morning in at least 4 consecutive days (mean 6.8 days) prior to the day of surgery. Large (≥4 mm), ulcerated, or mobile plaques were defined as complex plaques using transesophageal echocardiography. RESULTS: Cigarette smoking and all systolic BP variables were associated with the presence of complex plaques (p < 0.05), whereas diastolic BP variables were not. Multiple regression analysis indicated that day-by-day mean systolic BP and day-by-day systolic BP variability remained independently associated with the presence of complex plaques (p < 0.05) after adjustment for age, male sex, cigarette smoking, hypertension, hypercholesterolemia, and diabetes mellitus. CONCLUSIONS: These findings suggest that higher day-by-day mean systolic BP and day-by-day systolic BP variability are associated with complex plaques in the aortic arch and consequently stroke risk in patients with aortic stenosis.

DOI： 10.1016/j.atherosclerosis.2015.04.807

PubMed
Aortic arch atherosclerosis in patients with severe aortic stenosis can be argued by greater day-by-day blood pressure variability. Reviewed

Shinichi Iwata, Kenichi Sugioka, Suwako Fujita, Asahiro Ito, Yoshiki Matsumura, Akihisa Hanatani, Masahiko Takagi, Marco R Di Tullio, Shunichi Homma, Minoru Yoshiyama

Atherosclerosis 241 ( 1 ) 42 - 7 2015.07（ ISSN:0021-9150 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

BACKGROUND AND PURPOSE: Although it is well known that the prevalence of aortic arch plaques, one of the risk factors for ischemic stroke, is high in patients with severe aortic stenosis, the underlying mechanisms are not well understood. Increased day-by-day blood pressure (BP) variability is also known to be associated with stroke; however, little is known on the association between day-by-bay BP variability and aortic arch atherosclerosis in patients with aortic stenosis. Our objective was to clarify the association between day-by-day BP variables (average values and variability) and aortic arch atherosclerosis in patients with severe aortic stenosis. METHODS: The study population consisted of 104 consecutive patients (mean age 75 ± 8 years) with severe aortic stenosis who were scheduled for aortic valve replacement. BP was measured in the morning in at least 4 consecutive days (mean 6.8 days) prior to the day of surgery. Large (≥4 mm), ulcerated, or mobile plaques were defined as complex plaques using transesophageal echocardiography. RESULTS: Cigarette smoking and all systolic BP variables were associated with the presence of complex plaques (p < 0.05), whereas diastolic BP variables were not. Multiple regression analysis indicated that day-by-day mean systolic BP and day-by-day systolic BP variability remained independently associated with the presence of complex plaques (p < 0.05) after adjustment for age, male sex, cigarette smoking, hypertension, hypercholesterolemia, and diabetes mellitus. CONCLUSIONS: These findings suggest that higher day-by-day mean systolic BP and day-by-day systolic BP variability are associated with complex plaques in the aortic arch and consequently stroke risk in patients with aortic stenosis.

DOI： 10.1016/j.atherosclerosis.2015.04.807

PubMed
Predictors of silent brain infarction on magnetic resonance imaging in patients with nonvalvular atrial fibrillation: A transesophageal echocardiographic study Reviewed

Sugioka Kenichi, Takagi Masahiko, Sakamoto Shinichi, Fujita Suwako, Ito Asahiro, Iwata Shinichi, Matsumura Yoshiki, Nakagawa Masashi, Doi Atsushi, Miki Yukio, Yoshiyama Minoru, Ueda Makiko

MOSBY-ELSEVIER　AMERICAN HEART JOURNAL 169 ( 6 ) 783 - 790 2015.06（ ISSN:0002-8703 ）

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Publishing type：Research paper (scientific journal)

BACKGROUND: Silent brain infarction (SBI) is often found in patients with atrial fibrillation (AF) and may be related to cognitive decline. We investigated the predictors of SBI on brain magnetic resonance imaging (MRI) using transesophageal echocardiography (TEE) in patients with nonvalvular AF. METHODS: The study population consisted of 103 neurologically asymptomatic patients with nonvalvular AF who underwent TEE before transcatheter AF ablation (76 men; mean age 63 ± 10 years). Left atrial (LA) abnormalities such as LA thrombus, spontaneous echo contrast, or abnormal LA appendage emptying velocity (<20 cm/s) and complex plaques in the aortic arch defined as large plaques ≥4 mm thickness, ulcerated plaques, or mobile plaques were evaluated by TEE. All patients were screened for SBI by brain MRI. RESULTS: Of 103 patients, 31 (30%) showed SBI on brain MRI. Most lesions were multiple (61%) and small (<15 mm) in diameter (84%). Patients with SBI had a higher prevalence of LA abnormalities (45% vs 14%; P < .001) and complex arch plaques (45% vs 7%; P < .001) compared with those without SBI. In a multivariate logistic regression analysis including age and CHADS2 score ≥2, LA abnormalities (odds ratio 4.13; 95% CI 1.34-12.72; P = .014) and complex arch plaques (odds ratio 4.82; 95% CI 1.23-18.92; P = .024) were independent predictors of SBI. CONCLUSIONS: Left atrial abnormalities and complex arch plaques detected by TEE were closely associated with the presence of SBI on brain MRI, suggesting that microembolization of small thrombi derived from the fibrillating LA or advanced aortic atherosclerotic lesions may be important causes of SBI in patients with nonvalvular AF.

DOI： 10.1016/j.ahj.2015.03.016

PubMed
Predictors of silent brain infarction on magnetic resonance imaging in patients with nonvalvular atrial fibrillation: A transesophageal echocardiographic study. Reviewed

Kenichi Sugioka, Masahiko Takagi, Shinichi Sakamoto, Suwako Fujita, Asahiro Ito, Shinichi Iwata, Yoshiki Matsumura, Masashi Nakagawa, Atsushi Doi, Yukio Miki, Minoru Yoshiyama, Makiko Ueda

American heart journal 169 ( 6 ) 783 - 90 2015.06（ ISSN:0002-8703 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

BACKGROUND: Silent brain infarction (SBI) is often found in patients with atrial fibrillation (AF) and may be related to cognitive decline. We investigated the predictors of SBI on brain magnetic resonance imaging (MRI) using transesophageal echocardiography (TEE) in patients with nonvalvular AF. METHODS: The study population consisted of 103 neurologically asymptomatic patients with nonvalvular AF who underwent TEE before transcatheter AF ablation (76 men; mean age 63 ± 10 years). Left atrial (LA) abnormalities such as LA thrombus, spontaneous echo contrast, or abnormal LA appendage emptying velocity (<20 cm/s) and complex plaques in the aortic arch defined as large plaques ≥4 mm thickness, ulcerated plaques, or mobile plaques were evaluated by TEE. All patients were screened for SBI by brain MRI. RESULTS: Of 103 patients, 31 (30%) showed SBI on brain MRI. Most lesions were multiple (61%) and small (<15 mm) in diameter (84%). Patients with SBI had a higher prevalence of LA abnormalities (45% vs 14%; P < .001) and complex arch plaques (45% vs 7%; P < .001) compared with those without SBI. In a multivariate logistic regression analysis including age and CHADS2 score ≥2, LA abnormalities (odds ratio 4.13; 95% CI 1.34-12.72; P = .014) and complex arch plaques (odds ratio 4.82; 95% CI 1.23-18.92; P = .024) were independent predictors of SBI. CONCLUSIONS: Left atrial abnormalities and complex arch plaques detected by TEE were closely associated with the presence of SBI on brain MRI, suggesting that microembolization of small thrombi derived from the fibrillating LA or advanced aortic atherosclerotic lesions may be important causes of SBI in patients with nonvalvular AF.

DOI： 10.1016/j.ahj.2015.03.016

PubMed
Association between chronic kidney disease and thoracic aortic atherosclerosis detected using transesophageal echocardiography Reviewed

Matsumura Yoshiki, Sugioka Kenichi, Fujita Suwako, Ito Asahiro, Iwata Shinichi, Yoshiyama Minoru

ELSEVIER IRELAND LTD　ATHEROSCLEROSIS 237 ( 1 ) 301 - 306 2014.11（ ISSN:0021-9150 ）

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Publishing type：Research paper (scientific journal)

OBJECTIVE: Accelerated atherosclerosis occurs with a high frequency in patients with chronic kidney disease (CKD). We evaluated the association between CKD and thoracic aortic plaques using transesophageal echocardiography (TEE). METHODS: This study population consisted of 297 patients who underwent TEE. Aortic plaques were evaluated in the proximal thoracic aorta (PTA) (from the ascending aorta to the aortic arch) and the distal thoracic aorta (DTA) (the descending aorta) using TEE. Aortic plaques were defined as complex plaques of ≥4 mm thickness and with ulceration or mobile components. CKD was defined as the estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2). The association between CKD and aortic plaques was evaluated using multivariate analysis after adjusting for traditional atherosclerotic risk factors. RESULTS: Patients with CKD (n = 144) had a higher incidence of any plaques and complex plaques compared with those without CKD (n = 153) (85% vs. 47% and 42% vs. 17%, respectively, both P < 0.001). Univariate analysis indicated that the presence of CKD was significantly associated with complex plaques both in the DTA and the PTA (both, P < 0.001); however, multivariate analysis indicated that the presence of CKD was associated with only complex plaques in the DTA (P < 0.05), but not with those in the PTA. CONCLUSION: The presence of CKD was associated with complex aortic plaques, with this association being stronger for complex plaques in the DTA than those in the PTA.

DOI： 10.1016/j.atherosclerosis.2014.09.013

PubMed
Association between chronic kidney disease and thoracic aortic atherosclerosis detected using transesophageal echocardiography. Reviewed

Yoshiki Matsumura, Kenichi Sugioka, Suwako Fujita, Asahiro Ito, Shinichi Iwata, Minoru Yoshiyama

Atherosclerosis 237 ( 1 ) 301 - 6 2014.11（ ISSN:0021-9150 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

OBJECTIVE: Accelerated atherosclerosis occurs with a high frequency in patients with chronic kidney disease (CKD). We evaluated the association between CKD and thoracic aortic plaques using transesophageal echocardiography (TEE). METHODS: This study population consisted of 297 patients who underwent TEE. Aortic plaques were evaluated in the proximal thoracic aorta (PTA) (from the ascending aorta to the aortic arch) and the distal thoracic aorta (DTA) (the descending aorta) using TEE. Aortic plaques were defined as complex plaques of ≥4 mm thickness and with ulceration or mobile components. CKD was defined as the estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2). The association between CKD and aortic plaques was evaluated using multivariate analysis after adjusting for traditional atherosclerotic risk factors. RESULTS: Patients with CKD (n = 144) had a higher incidence of any plaques and complex plaques compared with those without CKD (n = 153) (85% vs. 47% and 42% vs. 17%, respectively, both P < 0.001). Univariate analysis indicated that the presence of CKD was significantly associated with complex plaques both in the DTA and the PTA (both, P < 0.001); however, multivariate analysis indicated that the presence of CKD was associated with only complex plaques in the DTA (P < 0.05), but not with those in the PTA. CONCLUSION: The presence of CKD was associated with complex aortic plaques, with this association being stronger for complex plaques in the DTA than those in the PTA.

DOI： 10.1016/j.atherosclerosis.2014.09.013

PubMed
RELATIONSHIP BETWEEN CHADS(2) SCORE AND COMPLEX AORTIC PLAQUES BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY IN PATIENTS WITH NONVALVULAR ATRIAL FIBRILLATION Reviewed

Sugioka Kenichi, Fujita Suwako, Iwata Shinichi, Ito Asahiro, Matsumura Yoshiki, Hanatani Akihisa, Doi Atsushi, Takagi Masahiko, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

ELSEVIER SCIENCE INC　ULTRASOUND IN MEDICINE AND BIOLOGY 40 ( 10 ) 2358 - 2364 2014.10（ ISSN:0301-5629 ）

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The CHADS2 score is widely used for risk stratification of thromboembolism in patients with non-valvular atrial fibrillation (NVAF). Although the correlation of CHADS2 score with left atrial (LA) abnormality as detected by transesophageal echocardiography (TEE) has been reported in previous studies, the relationship between CHADS2 score and complex aortic plaque, which is also a significant risk factor for thromboembolism, has not been fully investigated. We assessed aortic plaques by TEE in 150 patients age ≥ 55 y with NVAF. The prevalence of complex aortic plaques increased along with increases in CHADS2 score (p = 0.001). In a multivariate analysis that included atherosclerotic risk factors and LA abnormality, a CHADS2 score ≥2 was independently associated with the presence of complex aortic plaques (odds ratio [OR] 3.39; 95% confidence interval [CI], 1.29-8.90). A high CHADS2 score is closely associated with the presence of complex aortic plaques, which explains, in part, the increased risk of thromboembolism in NVAF patients with high CHADS2 score.

DOI： 10.1016/j.ultrasmedbio.2014.05.006

PubMed
Relationship between CHADS2 score and complex aortic plaques by transesophageal echocardiography in patients with nonvalvular atrial fibrillation. Reviewed

Kenichi Sugioka, Suwako Fujita, Shinichi Iwata, Asahiro Ito, Yoshiki Matsumura, Akihisa Hanatani, Atsushi Doi, Masahiko Takagi, Takahiko Naruko, Makiko Ueda, Minoru Yoshiyama

Ultrasound in medicine & biology 40 ( 10 ) 2358 - 64 2014.10（ ISSN:0301-5629 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

The CHADS2 score is widely used for risk stratification of thromboembolism in patients with non-valvular atrial fibrillation (NVAF). Although the correlation of CHADS2 score with left atrial (LA) abnormality as detected by transesophageal echocardiography (TEE) has been reported in previous studies, the relationship between CHADS2 score and complex aortic plaque, which is also a significant risk factor for thromboembolism, has not been fully investigated. We assessed aortic plaques by TEE in 150 patients age ≥ 55 y with NVAF. The prevalence of complex aortic plaques increased along with increases in CHADS2 score (p = 0.001). In a multivariate analysis that included atherosclerotic risk factors and LA abnormality, a CHADS2 score ≥2 was independently associated with the presence of complex aortic plaques (odds ratio [OR] 3.39; 95% confidence interval [CI], 1.29-8.90). A high CHADS2 score is closely associated with the presence of complex aortic plaques, which explains, in part, the increased risk of thromboembolism in NVAF patients with high CHADS2 score.

DOI： 10.1016/j.ultrasmedbio.2014.05.006

PubMed
The Importance of Activated Vitamin D for the Mineralization by the Osteocyte in Patients with Renal Hyperparathyroidism. Reviewed

Yajima Aiji, Tsuchiya Ken, Nitta Kosaku, Inaba Masaaki, Tominaga Yoshihiro, Amizuka Norio, Ito Akemi, Shindo Hironari

JOURNAL OF BONE AND MINERAL RESEARCH 29 S173 - S173 2014.02（ ISSN:0884-0431 ）

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RAPID AND ACCURATE ASSESSMENT OF AORTIC ARCH ATHEROSCLEROSIS USING SIMULTANEOUS MULTI-PLANE IMAGING BY TRANSESOPHAGEAL ECHOCARDIOGRAPHY Reviewed

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Iwata Shinichi, Hanatani Akihisa, Hozumi Takeshi, Ueda Makiko, Yoshiyama Minoru

Elsevier USA　ULTRASOUND IN MEDICINE AND BIOLOGY 39 ( 8 ) 1337 - 1342 2013.08（ ISSN:0301-5629 ）

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Transesophageal echocardiography (TEE) is widely used for the evaluation of aortic arch atherosclerosis which carries an increased risk of ischemic stroke. We investigated the feasibility of simultaneous multi-plane imaging by real-time 3-D TEE for the assessment of aortic arch plaques. In 152 patients, we assessed aortic arch plaques and measured their maximum thickness by both conventional TEE imaging and multi-plane TEE imaging. There was excellent correlation and good agreement between the two methods in the measurement of the maximum thickness of arch plaques (r = 0.95, mean difference, -0.1 ± 0.5 mm). The mean image acquisition time required for aortic arch assessment by multi-plane imaging was significantly shorter than that required for conventional imaging in all patients (p < 0.001), especially those with complex plaques. These findings suggest that simultaneous multi-plane TEE imaging enables rapid and accurate evaluation of arch plaques and is therefore a useful tool for the assessment of aortic arch plaques in the clinical setting.

DOI： 10.1016/j.ultrasmedbio.2013.03.011

PubMed
Relationship between day-by-day blood pressure variability and aortic arch atherosclerosis Reviewed

Iwata S, Sugioka K, Matsumura Y, Fujita S, Ito A, Hozumi T, Hanatani A, Yoshiyama M

EUROPEAN HEART JOURNAL 34 1048 - 1048 2013.08（ ISSN:0195-668X ）

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Relationship between day-by-day blood pressure variability and aortic arch atherosclerosis Reviewed

Iwata S., Sugioka K., Matsumura Y., Fujita S., Ito A., Hozumi T., Hanatani A., Yoshiyama M.

EUROPEAN HEART JOURNAL 34 1048 - 1048 2013.08（ ISSN:0195-668X ）

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Rapid and accurate assessment of aortic arch atherosclerosis using simultaneous multi-plane imaging by transesophageal echocardiography. Reviewed

Asahiro Ito, Kenichi Sugioka, Yoshiki Matsumura, Suwako Fujita, Shinichi Iwata, Akihisa Hanatani, Takeshi Hozumi, Makiko Ueda, Minoru Yoshiyama

Ultrasound in medicine & biology 39 ( 8 ) 1337 - 42 2013.08（ ISSN:1879-291X ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

Transesophageal echocardiography (TEE) is widely used for the evaluation of aortic arch atherosclerosis which carries an increased risk of ischemic stroke. We investigated the feasibility of simultaneous multi-plane imaging by real-time 3-D TEE for the assessment of aortic arch plaques. In 152 patients, we assessed aortic arch plaques and measured their maximum thickness by both conventional TEE imaging and multi-plane TEE imaging. There was excellent correlation and good agreement between the two methods in the measurement of the maximum thickness of arch plaques (r = 0.95, mean difference, -0.1 ± 0.5 mm). The mean image acquisition time required for aortic arch assessment by multi-plane imaging was significantly shorter than that required for conventional imaging in all patients (p < 0.001), especially those with complex plaques. These findings suggest that simultaneous multi-plane TEE imaging enables rapid and accurate evaluation of arch plaques and is therefore a useful tool for the assessment of aortic arch plaques in the clinical setting.

DOI： 10.1016/j.ultrasmedbio.2013.03.011

PubMed
Relationship between day-by-day blood pressure variability and aortic arch atherosclerosis Reviewed

Iwata S, Sugioka K, Matsumura Y, Fujita S, Ito A, Hozumi T, Hanatani A, Yoshiyama M

EUROPEAN HEART JOURNAL 34 1048 - 1048 2013.08（ ISSN:0195-668X ）

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Publishing type：Research paper (scientific journal)
Impact of Concomitant Coronary Artery Disease on Atherosclerotic Plaques in the Aortic Arch in Patients With Severe Aortic Stenosis Reviewed

Fujita Suwako, Sugioka Kenichi, Matsumura Yoshiki, Ito Asahiro, Hozumi Takeshi, Hasegawa Takao, Hanatani Akihisa, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

WILEY-BLACKWELL　CLINICAL CARDIOLOGY 36 ( 6 ) 352 - 357 2013.06（ ISSN:0160-9289 ）

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Publishing type：Research paper (scientific journal)

BACKGROUND: Coronary artery disease (CAD) often occurs concurrently in patients with severe aortic stenosis (AS). However, the influence of concomitant CAD on the presence of atherosclerotic complex plaques in the aortic arch, which is associated with increased stroke risk, has not been fully assessed in patients with severe AS. HYPOTHESIS: We hypothesized that concomitant CAD would be associated with the presence of complex arch plaques in patients with severe AS. METHODS: The study population consisted of 154 patients with severe AS who had undergone transesophageal echocardiography (TEE) and coronary angiography (71 male; mean age, 72 ± 8 years; mean aortic valve area, 0.67 ± 0.15 cm(2) ). Aortic arch plaques were assessed using TEE, and complex arch plaques were defined as large plaques (≥4 mm), ulcerated plaques, or mobile plaques. RESULTS: The prevalence of aortic arch plaques (87% vs 70%; P = 0.03) and complex arch plaques (48% vs 20%; P < 0.001) was significantly greater in AS patients with CAD than in those without CAD. After adjustment for traditional atherosclerotic risk factors, we found that concomitant CAD was independently associated with the presence of complex arch plaques (odds ratio: 2.86, 95% confidence interval: 1.23-6.68, P = 0.01). CONCLUSIONS: In patients with severe AS, concomitant CAD is associated with severe atherosclerotic burden in the aortic arch. This observation suggests that AS patients with concomitant CAD are at a higher risk for stroke, and that careful evaluation of complex arch plaques by TEE is needed for the risk stratification of stroke in these patients.

DOI： 10.1002/clc.22121

PubMed
Impact of concomitant coronary artery disease on atherosclerotic plaques in the aortic arch in patients with severe aortic stenosis. Reviewed

Suwako Fujita, Kenichi Sugioka, Yoshiki Matsumura, Asahiro Ito, Takeshi Hozumi, Takao Hasegawa, Akihisa Hanatani, Takahiko Naruko, Makiko Ueda, Minoru Yoshiyama

Clinical cardiology 36 ( 6 ) 352 - 7 2013.06（ ISSN:0160-9289 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

BACKGROUND: Coronary artery disease (CAD) often occurs concurrently in patients with severe aortic stenosis (AS). However, the influence of concomitant CAD on the presence of atherosclerotic complex plaques in the aortic arch, which is associated with increased stroke risk, has not been fully assessed in patients with severe AS. HYPOTHESIS: We hypothesized that concomitant CAD would be associated with the presence of complex arch plaques in patients with severe AS. METHODS: The study population consisted of 154 patients with severe AS who had undergone transesophageal echocardiography (TEE) and coronary angiography (71 male; mean age, 72 ± 8 years; mean aortic valve area, 0.67 ± 0.15 cm(2) ). Aortic arch plaques were assessed using TEE, and complex arch plaques were defined as large plaques (≥4 mm), ulcerated plaques, or mobile plaques. RESULTS: The prevalence of aortic arch plaques (87% vs 70%; P = 0.03) and complex arch plaques (48% vs 20%; P < 0.001) was significantly greater in AS patients with CAD than in those without CAD. After adjustment for traditional atherosclerotic risk factors, we found that concomitant CAD was independently associated with the presence of complex arch plaques (odds ratio: 2.86, 95% confidence interval: 1.23-6.68, P = 0.01). CONCLUSIONS: In patients with severe AS, concomitant CAD is associated with severe atherosclerotic burden in the aortic arch. This observation suggests that AS patients with concomitant CAD are at a higher risk for stroke, and that careful evaluation of complex arch plaques by TEE is needed for the risk stratification of stroke in these patients.

DOI： 10.1002/clc.22121

PubMed
Rapid and Accurate Assessment of Aortic Arch Atherosclerosis Using Real-time 3 Dimensional Transesophageal Echocardiography Reviewed

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Iwata Shinichi, Fujita Suwako, Hozumi Takeshi, Yoshiyama Minoru

CIRCULATION 126 ( 21 ) 2012.11（ ISSN:0009-7322 ）

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Rapid and Accurate Assessment of Aortic Arch Atherosclerosis Using Real-time 3 Dimensional Transesophageal Echocardiography Reviewed

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Iwata Shinichi, Fujita Suwako, Hozumi Takeshi, Yoshiyama Minoru

CIRCULATION 126 ( 21 ) 2012.11（ ISSN:0009-7322 ）

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Publishing type：Research paper (scientific journal)
Rapid and Accurate Assessment of Aortic Arch Atherosclerosis Using Real-time 3 Dimensional Transesophageal Echocardiography Reviewed

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Iwata Shinichi, Fujita Suwako, Hozumi Takeshi, Yoshiyama Minoru

CIRCULATION 126 ( 21 ) 2012.11（ ISSN:0009-7322 ）

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Publishing type：Research paper (scientific journal)
Relation of Aortic Arch Complex Plaques to Risk of Cerebral Infarction in Patients With Aortic Stenosis Reviewed

Sugioka Kenichi, Matsumura Yoshiki, Hozumi Takeshi, Fujita Suwako, Ito Asahiro, Kataoka Toru, Takagi Masahiko, Mizutani Kazuki, Naruko Takahiko, Hosono Mitsuharu, Hirai Hidekazu, Sasaki Yasuyuki, Ueda Makiko, Suehiro Shigefumi, Yoshiyama Minoru

EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC　AMERICAN JOURNAL OF CARDIOLOGY 108 ( 7 ) 1002 - 1007 2011.10（ ISSN:0002-9149 ）

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Publishing type：Research paper (scientific journal)

Aortic stenosis (AS) and systemic atherosclerosis have been shown to be closely related. We evaluated the prevalence of aortic arch plaques and their possible association with the risk of cerebral infarction in patients with severe AS. Transesophageal echocardiography was performed in 116 patients with severe AS (55 men, mean age 71 ± 7 years, mean aortic valve area 0.68 ± 0.15 cm(2)) who were scheduled for aortic valve replacement. The presence, thickness, and morphology of the aortic arch plaques were evaluated using transesophageal echocardiography. Cerebral infarcts (chronic cerebral infarction and cerebral infarction after cardiac catheterization and aortic valve replacement) were assessed in all patients. Compared to age- and gender-matched control subjects, the patients with severe AS had a significantly greater prevalence of aortic arch plaques (74% vs 41%; p <0.0001) and complex arch plaques such as large plaques (≥4 mm), ulcerated plaques, or mobile plaques (30% vs 10%; p = 0.004). Multivariate logistic analyses showed that the presence of complex arch plaques was independently associated with cerebral infarction in patients with AS after adjusting for traditional atherosclerotic risk factors and coronary artery disease (odds ratio 8.46, 95% confidence interval 2.38 to 30.12; p = 0.001). In conclusion, the results from the present study showed that there is a greater prevalence of aortic arch plaques in patients with AS and that the presence of complex plaques is independently associated with cerebral infarction in these patients. Therefore, the identification of complex arch plaques using transesophageal echocardiography is important for risk stratification of cerebrovascular events in patients with severe AS.

DOI： 10.1016/j.amjcard.2011.05.036

PubMed
Relation of aortic arch complex plaques to risk of cerebral infarction in patients with aortic stenosis. Reviewed

Kenichi Sugioka, Yoshiki Matsumura, Takeshi Hozumi, Suwako Fujita, Asahiro Ito, Toru Kataoka, Masahiko Takagi, Kazuki Mizutani, Takahiko Naruko, Mitsuharu Hosono, Hidekazu Hirai, Yasuyuki Sasaki, Makiko Ueda, Shigefumi Suehiro, Minoru Yoshiyama

The American journal of cardiology 108 ( 7 ) 1002 - 7 2011.10（ ISSN:0002-9149 ）

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Publishing type：Research paper (scientific journal) International / domestic magazine：International journal

Aortic stenosis (AS) and systemic atherosclerosis have been shown to be closely related. We evaluated the prevalence of aortic arch plaques and their possible association with the risk of cerebral infarction in patients with severe AS. Transesophageal echocardiography was performed in 116 patients with severe AS (55 men, mean age 71 ± 7 years, mean aortic valve area 0.68 ± 0.15 cm(2)) who were scheduled for aortic valve replacement. The presence, thickness, and morphology of the aortic arch plaques were evaluated using transesophageal echocardiography. Cerebral infarcts (chronic cerebral infarction and cerebral infarction after cardiac catheterization and aortic valve replacement) were assessed in all patients. Compared to age- and gender-matched control subjects, the patients with severe AS had a significantly greater prevalence of aortic arch plaques (74% vs 41%; p <0.0001) and complex arch plaques such as large plaques (≥4 mm), ulcerated plaques, or mobile plaques (30% vs 10%; p = 0.004). Multivariate logistic analyses showed that the presence of complex arch plaques was independently associated with cerebral infarction in patients with AS after adjusting for traditional atherosclerotic risk factors and coronary artery disease (odds ratio 8.46, 95% confidence interval 2.38 to 30.12; p = 0.001). In conclusion, the results from the present study showed that there is a greater prevalence of aortic arch plaques in patients with AS and that the presence of complex plaques is independently associated with cerebral infarction in these patients. Therefore, the identification of complex arch plaques using transesophageal echocardiography is important for risk stratification of cerebrovascular events in patients with severe AS.

DOI： 10.1016/j.amjcard.2011.05.036

PubMed

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MISC

Endoscopic assessment of WATCHMAN 17 months after implantation(タイトル和訳中)

Yamazaki Takanori, Yoshiyama Tomotaka, Ito Asahiro, Izumiya Yasuhiro, Fukuda Daiju

Cardiovascular Intervention and Therapeutics 38 ( 2 ) 258 - 259 2023.04（ ISSN:1868-4300 ）
経カテーテル大動脈弁置換術中の大動脈弁尖の非可逆性反転(Irreversible reversal of aortic valve leaflet during transcatheter aortic valve implantation)

Ogawa Mana, Mizutani Kazuki, Okai Tsukasa, Ito Asahiro, Iwata Shinichi, Yoshiyama Minoru

Cardiovascular Intervention and Therapeutics 36 ( 4 ) 553 - 554 2021.10（ ISSN:1868-4300 ）
POST-PROCEDURAL CARDIO-ANKLE VASCULAR INDEX IS ASSOCIATED WITH ONE-YEAR MORTALITY IN PATIENTS WHO UNDERWENT TRANS-FEMORAL TAVR

Tomohiro Yamaguchi, Kazuki Mizutani, Ryousuke Yahiro, Mana Ogawa, Tsukasa Okai, Shinichi Nonin, Asahiro Ito, Shinichi Iwata, Yasuhiro Izumiya, Yosuke Takahashi, Toshihiko Shibata, Minoru Yoshiyama

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 75 ( 11 ) 1243 - 1243 2020.03（ ISSN:0735-1097 ）（ eISSN:1558-3597 ）

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Publishing type：Research paper, summary (international conference)
Complication & Bailout of TAVI(Case-Based)1 自己拡張弁導入の際に自己弁尖が左室側に反転し、急性大動脈弁閉鎖不全を来たした1例どのようにbail-outしますか? Reviewed

水谷一輝, 山口智大, 小川真奈, 岡井主, 伊藤朝広, 岩田真一, 泉家康宏, 葭山稔

(一社)日本心血管インターベンション治療学会　日本心血管インターベンション治療学会抄録集 28回 [S29 - 2] 2019.09

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TAVI後の凝固線溶系因子の上昇に関する予測因子の検討抗凝固療法が有効? Reviewed

岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

(一社)日本心血管インターベンション治療学会　日本心血管インターベンション治療学会抄録集 28回 [MO96 - 002] 2019.09

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冠動脈3枝病変、下大静脈欠損を伴うASDを合併したsevere ASに対して、カテーテル治療で完遂し得た1例 Reviewed

山本崇之, 岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

(一社)日本心血管インターベンション治療学会　日本心血管インターベンション治療学会抄録集 28回 [MO120 - 004] 2019.09

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冠動脈3枝病変、下大静脈欠損を伴うASDを合併したsevere ASに対して、カテーテル治療で完遂し得た1例

山本崇之, 岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 28回 [MO120 - 004] 2019.09
TAVI後の凝固線溶系因子の上昇に関する予測因子の検討抗凝固療法が有効?

岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 28回 [MO96 - 002] 2019.09
Complication & Bailout of TAVI(Case-Based)1 自己拡張弁導入の際に自己弁尖が左室側に反転し、急性大動脈弁閉鎖不全を来たした1例どのようにbail-outしますか?

水谷一輝, 山口智大, 小川真奈, 岡井主, 伊藤朝広, 岩田真一, 泉家康宏, 葭山稔

日本心血管インターベンション治療学会抄録集 28回 [S29 - 2] 2019.09
発作性と持続性の非弁膜症性心房細動患者における無症候性脳梗塞の有病率およびリスク因子の差(Differences in Prevalence and Risk Factors of Silent Brain Infarction between Patients with Paroxysmal and Persistentnonvalvular Atrial Fibrillation) Reviewed

石川世良, 岩田真一, 伊藤朝広, 田村聡一郎, 河相優, 吉山智貴, 辰巳裕亮, 土井淳史, 泉家康宏, 葭山稔

(一社)日本循環器学会　日本循環器学会学術集会抄録集 83回 OJ17 - 6 2019.03

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Differences in Prevalence and Risk Factors of Silent Brain Infarction between Patients with Paroxysmal and Persistentnonvalvular Atrial Fibrillation(和訳中) Reviewed

石川世良, 岩田真一, 伊藤朝広, 田村聡一郎, 河相優, 吉山智貴, 辰巳裕亮, 土井淳史, 泉家康宏, 葭山稔

(一社)日本循環器学会, 日本循環器学会学術集会抄録集 83回 OJ17 - 6 2019.03

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発作性と持続性の非弁膜症性心房細動患者における無症候性脳梗塞の有病率およびリスク因子の差(Differences in Prevalence and Risk Factors of Silent Brain Infarction between Patients with Paroxysmal and Persistentnonvalvular Atrial Fibrillation)

石川世良, 岩田真一, 伊藤朝広, 田村聡一郎, 河相優, 吉山智貴, 辰巳裕亮, 土井淳史, 泉家康宏, 葭山稔

日本循環器学会学術集会抄録集 83回 OJ17 - 6 2019.03
Differences in Prevalence and Risk Factors of Silent Brain Infarction between Patients with Paroxysmal and Persistentnonvalvular Atrial Fibrillation(和訳中)

石川世良, 岩田真一, 伊藤朝広, 田村聡一郎, 河相優, 吉山智貴, 辰巳裕亮, 土井淳史, 泉家康宏, 葭山稔

日本循環器学会学術集会抄録集 83回 OJ17 - 6 2019.03
非弁膜症性心房細動患者における組織ドプラ法による左室拡張能評価と無症候性脳梗塞の関連性 Reviewed

石川世良, 杉岡憲一, 坂本真一, 藤田澄吾子, 伊藤朝広, 則岡直樹, 岩田真一, 仲川将志, 高木雅彦, 三木幸雄, 上田真喜子, 葭山稔

大阪市医学会, 大阪市医学会雑誌 67 74 - 74 2018.12（ ISSN:0386-4103 ）

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J-GLOBAL
非弁膜症性心房細動患者における組織ドプラ法による左室拡張能評価と無症候性脳梗塞の関連性

石川世良, 杉岡憲一, 坂本真一, 藤田澄吾子, 伊藤朝広, 則岡直樹, 岩田真一, 仲川将志, 高木雅彦, 三木幸雄, 上田真喜子, 葭山稔

大阪市医学会雑誌 67 74 - 74 2018.12（ ISSN:0386-4103 ）

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J-GLOBAL
Left Ventricular Outpouchingを有する重症大動脈弁狭窄症に対して経カテーテル的大動脈弁植え込み術を施行し得た2症例 Reviewed

梶尾啓子, 水谷一輝, 中尾真奈, 岡井主, 野元陽太, 伊藤朝広, 山崎貴紀, 岩田真一, 紙森公雄, 葭山稔

(一社)日本心血管インターベンション治療学会, 日本心血管インターベンション治療学会抄録集 27回 MO428 - MO428 2018.08

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僧帽弁狭窄症のTAVR直後に生じる心不全増悪への関与 Reviewed

岡井主, 水谷一輝, 中尾真奈, 梶尾啓子, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

(一社)日本心血管インターベンション治療学会, 日本心血管インターベンション治療学会抄録集 27回 PP17 - 2 2018.08

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Left Ventricular Outpouchingを有する重症大動脈弁狭窄症に対して経カテーテル的大動脈弁植え込み術を施行し得た2症例

梶尾啓子, 水谷一輝, 中尾真奈, 岡井主, 野元陽太, 伊藤朝広, 山崎貴紀, 岩田真一, 紙森公雄, 葭山稔

日本心血管インターベンション治療学会抄録集 27回 MO428 - MO428 2018.08
僧帽弁狭窄症のTAVR直後に生じる心不全増悪への関与

岡井主, 水谷一輝, 中尾真奈, 梶尾啓子, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 27回 PP17 - 2 2018.08
PFOかASDか診断・治療に苦慮した奇異性塞栓の1例 Reviewed

水谷一輝, 中尾真奈, 岡井主, 梶尾啓子, 伊藤朝広, 岩田真一, 葭山稔

日本心血管脳卒中学会学術集会プログラム・抄録集 5th 150 2018.06

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J-GLOBAL
PFOかASDか診断・治療に苦慮した奇異性塞栓の1例

水谷一輝, 中尾真奈, 岡井主, 梶尾啓子, 伊藤朝広, 岩田真一, 葭山稔

日本心血管脳卒中学会学術集会プログラム・抄録集 5th 150 2018.06

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J-GLOBAL
重度の大動脈弁狭窄を有する患者において自己拡張型バルブは経カテーテル大動脈弁置換術後にDW-MRIにより検出される高信号のスポットに影響を及ぼす(Self-Expandable Valve Affects High Intensity Spots Detected by DW-MRI after Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis) Reviewed

吉田啓子, 水谷一輝, 原正彦, 中尾真奈, 岡井主, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

(一社)日本循環器学会, 日本循環器学会学術集会抄録集 82回 PJ036 - 7 2018.03

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重度の大動脈弁狭窄を有する患者において自己拡張型バルブは経カテーテル大動脈弁置換術後にDW-MRIにより検出される高信号のスポットに影響を及ぼす(Self-Expandable Valve Affects High Intensity Spots Detected by DW-MRI after Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis)

吉田啓子, 水谷一輝, 原正彦, 中尾真奈, 岡井主, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 82回 PJ036 - 7 2018.03
高度三尖大動脈弁狭窄症,冠動脈三枝病変に,高度二尖弁肺動脈弁狭窄症を合併した一例 Reviewed

伊藤朝広, 岩田真一, 田村聡一郎, 石川世良, 中尾真奈, 江原省一, 泉家康宏, 村上貴志, 柴田利彦, 葭山稔

日本循環器学会近畿地方会(Web) 126th KINKI126,C18 (WEB ONLY) 2018

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J-GLOBAL
心室中隔欠損を伴う肺動脈閉鎖症術後遠隔期に生じた人工弁機能不全を三次元心エコーにて観察し得た一例 Reviewed

山本崇之, 岩田真一, 山口祐美, 田村聡一郎, 石川世良, 伊藤朝広, 水谷一輝, 江原省一, 泉家康宏, 葭山稔

日本循環器学会近畿地方会(Web) 126th KINKI126,A13 (WEB ONLY) 2018

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J-GLOBAL
免疫チェックポイント阻害薬による心毒性が疑われた一例 Reviewed

伊藤文花, 伊藤文花, 伊藤朝広, 岩田真一, 田村聡一郎, 石川世良, 江原省一, 泉家康宏, 葭山稔

日本循環器学会近畿地方会(Web) 125th KINKI125,D06 (WEB ONLY) 2018

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J-GLOBAL
心エコー図検査を契機に発見された未破裂バルサルバ洞動脈瘤の一例 Reviewed

中尾真奈, 石川世良, 田村聡一郎, 伊藤朝広, 岩田真一, 泉家康宏, 葭山稔

日本循環器学会近畿地方会(Web) 125th KINKI125,C01 (WEB ONLY) 2018

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J-GLOBAL
大動脈二尖弁のSevere ASに対してTAVRが有効であった1例 Reviewed

岡井主, 水谷一輝, 中尾真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本循環器学会近畿地方会(Web) 125th KINKI125,D17 (WEB ONLY) 2018

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J-GLOBAL
新時代のバルーン大動脈弁形成術経食道心エコーガイドのポイントと手技のtips&tricks Reviewed

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

(一社)日本心血管インターベンション治療学会, 日本心血管インターベンション治療学会抄録集 26回 S10 - 3 2017.07

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新時代のバルーン大動脈弁形成術経食道心エコーガイドのポイントと手技のtips&tricks

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 26回 S10 - 3 2017.07
経カテーテル的大動脈弁置換術中に血行動態破綻を来す急性僧帽弁閉鎖不全症の予測因子 Reviewed

伊藤朝広, 岩田真一, 水谷一輝, 土井淳史, 花谷彰久, 高橋洋介, 山田徳洪, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会　日本循環制御医学会総会プログラム・抄録集 38回 99 - 99 2017.06

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重症大動脈弁狭窄症患者における3次元経食道心エコーガイド下で施行する順行性大動脈弁バルーン形成術の頻回拡張の安全性と有効性について Reviewed

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会　日本循環制御医学会総会プログラム・抄録集 38回 101 - 101 2017.06

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経カテーテル的大動脈弁置換術中に血行動態破綻を来す急性僧帽弁閉鎖不全症の予測因子

伊藤朝広, 岩田真一, 水谷一輝, 土井淳史, 花谷彰久, 高橋洋介, 山田徳洪, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会総会プログラム・抄録集 38回 99 - 99 2017.06
重症大動脈弁狭窄症患者における3次元経食道心エコーガイド下で施行する順行性大動脈弁バルーン形成術の頻回拡張の安全性と有効性について

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会総会プログラム・抄録集 38回 101 - 101 2017.06
より安全な心血管インターベンションを目指してメディカルスタッフに求めたい安全のための技量 Reviewed

水谷一輝, 伊藤朝広, 高尾由範, 西村慎亮, 岩田真一, 高橋洋介, 村上貴志, 山田徳洪, 市田隆雄, 柴田利彦, 葭山稔

(一社)日本循環器学会　日本循環器学会学術集会抄録集 81回 CS4 - 5 2017.03

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より安全な心血管インターベンションを目指してメディカルスタッフに求めたい安全のための技量

水谷一輝, 伊藤朝広, 高尾由範, 西村慎亮, 岩田真一, 高橋洋介, 村上貴志, 山田徳洪, 市田隆雄, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 81回 CS4 - 5 2017.03
PDA先行治療で心不全症状が改善したASの一例 Reviewed

梶尾啓子, 水谷一輝, 中尾真奈, 岡井主, 野元陽太, 伊藤朝広, 山崎貴紀, 岩田真一, 紙森公雄, 葭山稔

日本循環器学会近畿地方会(Web) 124th KINKI124,G01 (WEB ONLY) 2017

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J-GLOBAL
心エコー図検査にて長期的に経過を追えたジストロフィン遺伝子関連拡張型心筋症と考えられた一例 Reviewed

中尾真奈, 能仁信一, 伊藤朝広, 田村聡一郎, 河相優, 石川世良, 岩田真一, 土井淳史, 花谷彰久, 葭山稔

日本循環器学会近畿地方会(Web) 124th KINKI124,G43 (WEB ONLY) 2017

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J-GLOBAL
多孔性心房中隔欠損症に対して経皮的心房中隔欠損閉鎖術を施行した一例 Reviewed

伊藤文花, 石川世良, 岩田真一, 田村総一郎, 河相優, 能仁信一, 伊藤朝広, 葭山稔

日本循環器学会近畿地方会(Web) 124th KINKI124,H53 (WEB ONLY) 2017

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J-GLOBAL
Elevated Left Ventricular Diastolic Filling Pressure by Tissue Doppler Imaging and Silent Brain Infarction in Patients With Nonvalvular Atrial Fibrillation Reviewed

Sera Ishikawa, Kenichi Sugioka, Shinichi Iwata, Naoki Norioka, Shinichi Nonin, Yu Kawai, Suwako Fujita, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

LIPPINCOTT WILLIAMS & WILKINS　CIRCULATION 134 2016.11（ ISSN:0009-7322 ）

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Elevated Left Ventricular Diastolic Filling Pressure by Tissue Doppler Imaging and Silent Brain Infarction in Patients With Nonvalvular Atrial Fibrillation Reviewed

Sera Ishikawa, Kenichi Sugioka, Shinichi Iwata, Naoki Norioka, Shinichi Nonin, Yu Kawai, Suwako Fujita, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

LIPPINCOTT WILLIAMS & WILKINS　CIRCULATION 134 2016.11（ ISSN:0009-7322 ）

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Greater Nighttime Blood Pressure Variability is Associated With Left Atrial Enlargement in Atrial Fibrillation Patients With Preserved Ejection Fraction Reviewed

Naoki Norioka, Shinichi Iwata, Kenichi Sugioka, Yu Kawai, Shinichi Nonin, Suwako Fujita, Sera Ishikawa, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

LIPPINCOTT WILLIAMS & WILKINS　CIRCULATION 134 2016.11（ ISSN:0009-7322 ）

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Plaque Surface Irregularity and Calcification Length Within Carotid Plaque Predict Secondary Events in Patients With Coronary Artery Disease Reviewed

Shinichi Nonin, Shinichi Iwata, Kenichi Sugioka, Yu Kawai, Suwako Fujita, Sera Ishikawa, Naoki Norioka, Asahiro Ito, Masashi Nakagawa, Minoru Yoshiyama

LIPPINCOTT WILLIAMS & WILKINS　CIRCULATION 134 2016.11（ ISSN:0009-7322 ）

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Greater Nighttime Blood Pressure Variability is Associated With Left Atrial Enlargement in Atrial Fibrillation Patients With Preserved Ejection Fraction Reviewed

Naoki Norioka, Shinichi Iwata, Kenichi Sugioka, Yu Kawai, Shinichi Nonin, Suwako Fujita, Sera Ishikawa, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

LIPPINCOTT WILLIAMS & WILKINS　CIRCULATION 134 2016.11（ ISSN:0009-7322 ）

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Elevated Left Ventricular Diastolic Filling Pressure by Tissue Doppler Imaging and Silent Brain Infarction in Patients With Nonvalvular Atrial Fibrillation

Sera Ishikawa, Kenichi Sugioka, Shinichi Iwata, Naoki Norioka, Shinichi Nonin, Yu Kawai, Suwako Fujita, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

CIRCULATION 134 2016.11（ ISSN:0009-7322 ）（ eISSN:1524-4539 ）

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Plaque Surface Irregularity and Calcification Length Within Carotid Plaque Predict Secondary Events in Patients With Coronary Artery Disease

Shinichi Nonin, Shinichi Iwata, Kenichi Sugioka, Yu Kawai, Suwako Fujita, Sera Ishikawa, Naoki Norioka, Asahiro Ito, Masashi Nakagawa, Minoru Yoshiyama

CIRCULATION 134 2016.11（ ISSN:0009-7322 ）（ eISSN:1524-4539 ）

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Greater Nighttime Blood Pressure Variability is Associated With Left Atrial Enlargement in Atrial Fibrillation Patients With Preserved Ejection Fraction

Naoki Norioka, Shinichi Iwata, Kenichi Sugioka, Yu Kawai, Shinichi Nonin, Suwako Fujita, Sera Ishikawa, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

CIRCULATION 134 2016.11（ ISSN:0009-7322 ）（ eISSN:1524-4539 ）

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Publishing type：Research paper, summary (international conference)
Greater Nighttime Blood Pressure Variability is Associated With Left Atrial Enlargement in Atrial Fibrillation Patients With Preserved Ejection Fraction

Naoki Norioka, Shinichi Iwata, Kenichi Sugioka, Yu Kawai, Shinichi Nonin, Suwako Fujita, Sera Ishikawa, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

CIRCULATION 134 2016.11（ ISSN:0009-7322 ）（ eISSN:1524-4539 ）

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Publishing type：Research paper, summary (international conference)
Elevated Left Ventricular Diastolic Filling Pressure by Tissue Doppler Imaging and Silent Brain Infarction in Patients With Nonvalvular Atrial Fibrillation

Sera Ishikawa, Kenichi Sugioka, Shinichi Iwata, Naoki Norioka, Shinichi Nonin, Yu Kawai, Suwako Fujita, Asahiro Ito, Masahiko Takagi, Minoru Yoshiyama

CIRCULATION 134 2016.11（ ISSN:0009-7322 ）（ eISSN:1524-4539 ）

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重症大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討三尖弁と二尖弁大動脈弁狭窄症の比較 Reviewed

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 64回 P - 557 2016.09

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非弁膜症性心房細動における無症候性脳梗塞と左室充満圧(E/e')との関連 Reviewed

石川世良, 杉岡憲一, 岩田真一, 伊藤朝広, 河相優, 能仁信一, 藤田澄吾子, 則岡直樹, 高木雅彦, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 64回 O - 079 2016.09

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冠動脈疾患患者において、頸動脈plaque surface irregularityは心血管二次イベントの予測因子である Reviewed

能仁信一, 岩田真一, 杉岡憲一, 河相優, 藤田澄吾子, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 花谷彰久, 高木雅彦, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 64回 P - 077 2016.09

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非弁膜症性心房細動における無症候性脳梗塞と左室充満圧(E/e')との関連

石川世良, 杉岡憲一, 岩田真一, 伊藤朝広, 河相優, 能仁信一, 藤田澄吾子, 則岡直樹, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 64回 O - 079 2016.09
重症大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討三尖弁と二尖弁大動脈弁狭窄症の比較

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 64回 P - 557 2016.09
冠動脈疾患患者において、頸動脈plaque surface irregularityは心血管二次イベントの予測因子である

能仁信一, 岩田真一, 杉岡憲一, 河相優, 藤田澄吾子, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 64回 P - 077 2016.09
経食道心エコー図ガイド下による順行性大動脈弁バルーン拡張術の有効性と安全性について Reviewed

水谷一輝, 松岡雄治郎, 阪本勇也, 伊藤朝広, 岩田真一, 仲川将志, 白井伸幸, 杉岡憲一, 高木雅彦, 葭山稔

(一社)日本心血管インターベンション治療学会　日本心血管インターベンション治療学会抄録集 25回 MO169 - MO169 2016.07

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経食道心エコーガイド下で弁輪破裂を回避し得たantegrade BAVの一例 Reviewed

松岡雄治郎, 水谷一輝, 伊藤朝広, 岩田真一, 仲川将志, 杉岡憲一, 村上貴志, 細野光治, 高木雅彦, 柴田利彦, 葭山稔

(一社)日本心血管インターベンション治療学会　日本心血管インターベンション治療学会抄録集 25回 MP235 - MP235 2016.07

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経食道心エコーガイド下で弁輪破裂を回避し得たantegrade BAVの一例

松岡雄治郎, 水谷一輝, 伊藤朝広, 岩田真一, 仲川将志, 杉岡憲一, 村上貴志, 細野光治, 高木雅彦, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 25回 MP235 - MP235 2016.07
経食道心エコー図ガイド下による順行性大動脈弁バルーン拡張術の有効性と安全性について

水谷一輝, 松岡雄治郎, 阪本勇也, 伊藤朝広, 岩田真一, 仲川将志, 白井伸幸, 杉岡憲一, 高木雅彦, 葭山稔

日本心血管インターベンション治療学会抄録集 25回 MO169 - MO169 2016.07
大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討 Reviewed

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

(一社)日本動脈硬化学会　日本動脈硬化学会総会プログラム・抄録集 48回 204 - 204 2016.06（ ISSN:1347-7099 ）

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大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

日本動脈硬化学会総会プログラム・抄録集 48回 204 - 204 2016.06（ ISSN:1347-7099 ）
結節性紅斑との鑑別を要した感染性心内膜炎による敗血疹の1例 Reviewed

真鍋麻里奈, 今西久幹, 大迫順子, 梅田桜子, 伊藤朝広, 安水大介, 葭山稔, 鶴田大輔

(公社)日本皮膚科学会　日本皮膚科学会雑誌 126 ( 5 ) 955 - 955 2016.05（ ISSN:0021-499X ）

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結節性紅斑との鑑別を要した感染性心内膜炎による敗血疹の1例

真鍋麻里奈, 今西久幹, 大迫順子, 梅田桜子, 伊藤朝広, 安水大介, 葭山稔, 鶴田大輔

日本皮膚科学会雑誌 126 ( 5 ) 955 - 955 2016.05（ ISSN:0021-499X ）（ eISSN:1346-8146 ）
大動脈弓部動脈硬化性穿通性潰瘍と非連続性に限局性解離を合併した一例 Reviewed

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 石川世良, 安保浩二, 藤岡一也, 葭山稔

(公社)日本超音波医学会, 超音波医学 43 ( Suppl. ) S793 - S793 2016.04（ ISSN:1346-1176 ）

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左室駆出率が保持された心房細動患者において、夜間血圧変動性が左房拡大に与える影響 Reviewed

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 花谷彰久, 高木雅彦, 葭山稔

(公社)日本超音波医学会, 超音波医学 43 ( Suppl. ) S564 - S564 2016.04（ ISSN:1346-1176 ）

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大動脈弓部動脈硬化性穿通性潰瘍と非連続性に限局性解離を合併した一例

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 石川世良, 安保浩二, 藤岡一也, 葭山稔

超音波医学 43 ( Suppl. ) S793 - S793 2016.04（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
左室駆出率が保持された心房細動患者において、夜間血圧変動性が左房拡大に与える影響

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 花谷彰久, 高木雅彦, 葭山稔

超音波医学 43 ( Suppl. ) S564 - S564 2016.04（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
心不全発症を契機にミトコンドリア心筋症の診断に至った左室肥大の一例 Reviewed

市川佳誉, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 安保浩二, 藤岡一也, 葭山稔

(公社)日本超音波医学会　超音波医学 43 ( 2 ) 356 - 357 2016.03（ ISSN:1346-1176 ）

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カテーテルアブレーション施行8ヵ月後検出された右房内血栓の一例 Reviewed

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 阿保浩二, 藤岡一也, 桑江優子, 大澤政彦, 葭山稔

(公社)日本超音波医学会　超音波医学 43 ( 2 ) 354 - 354 2016.03（ ISSN:1346-1176 ）

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心エコーにて限局性の心筋炎が疑われた持続性心室頻拍の一例 Reviewed

寺下和範, 杉岡憲一, 岩田真一, 河相優, 藤田澄吾子, 伊藤朝広, 安保浩二, 藤岡一也, 葭山稔

(公社)日本超音波医学会　超音波医学 43 ( 2 ) 356 - 356 2016.03（ ISSN:1346-1176 ）

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完全房室ブロックをきたした心臓原発悪性リンパ腫の一例 Reviewed

武坂絢, 杉岡憲一, 岩田真一, 伊藤朝広, 藤田澄吾子, 阿保浩二, 藤岡一也, 葭山稔

(公社)日本超音波医学会　超音波医学 43 ( 2 ) 354 - 354 2016.03（ ISSN:1346-1176 ）

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カテーテルアブレーション施行8ヵ月後検出された右房内血栓の一例

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 阿保浩二, 藤岡一也, 桑江優子, 大澤政彦, 葭山稔

超音波医学 43 ( 2 ) 354 - 354 2016.03（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
心不全発症を契機にミトコンドリア心筋症の診断に至った左室肥大の一例

市川佳誉, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 安保浩二, 藤岡一也, 葭山稔

超音波医学 43 ( 2 ) 356 - 357 2016.03（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
心エコーにて限局性の心筋炎が疑われた持続性心室頻拍の一例

寺下和範, 杉岡憲一, 岩田真一, 河相優, 藤田澄吾子, 伊藤朝広, 安保浩二, 藤岡一也, 葭山稔

超音波医学 43 ( 2 ) 356 - 356 2016.03（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
完全房室ブロックをきたした心臓原発悪性リンパ腫の一例

武坂絢, 杉岡憲一, 岩田真一, 伊藤朝広, 藤田澄吾子, 阿保浩二, 藤岡一也, 葭山稔

超音波医学 43 ( 2 ) 354 - 354 2016.03（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
重症大動脈弁狭窄症患者における大動脈弓部の動脈硬化は日間血圧変動の増加により論ずることができるか? Reviewed

岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, Di Tullio MR, 本間俊一, 葭山稔

大阪市医学会　大阪市医学会雑誌 64 41 - 41 2015.12（ ISSN:0386-4103 ）

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重症大動脈弁狭窄症患者における大動脈弓部の動脈硬化は日間血圧変動の増加により論ずることができるか?

岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, Di Tullio MR, 本間俊一, 葭山稔

大阪市医学会雑誌 64 41 - 41 2015.12（ ISSN:0386-4103 ）
緊急非心臓手術術前に発覚した高度大動脈弁狭窄症に対して順行性大動脈弁バルーン形成術を施行した一例 Reviewed

寺下和範, 水谷一輝, 松岡雄治郎, 仲川将志, 藤田澄吾子, 坂本祥吾, 伊藤朝広, 岩田真一, 杉岡憲一, 高木雅彦, 柴田利彦, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 63回 908 - 908 2015.09

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非弁膜症性心房細動における無症候性脳梗塞発症のメカニズム経食道心エコーによる検討 Reviewed

杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 63回 1244 - 1244 2015.09

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非弁膜症性心房細動における無症候性脳梗塞のCHADS2スコアに与える影響 Reviewed

河相優, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 63回 1359 - 1359 2015.09

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重症大動脈弁狭窄症における僧帽弁輪石灰化の臨床的意義についての検討 Reviewed

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 63回 477 - 477 2015.09

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重症大動脈弁狭窄症において、日間血圧変動の増大は大動脈弓部complexプラークの独立した関連因子である Reviewed

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 63回 1171 - 1171 2015.09

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連合弁膜症例に対して、経食道心エコーガイド下で大動脈弁バルーン形成術および僧帽弁交連切開術を同時施行した一例 Reviewed

松岡雄治郎, 水谷一輝, 仲川将志, 藤田澄吾子, 伊藤朝広, 坂本祥吾, 岩田真一, 杉岡憲一, 柴田利彦, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 63回 344 - 344 2015.09

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透析困難症および重症心不全を伴う大動脈弁狭窄症に対して血行動態改善目的に逆行性大動脈弁バルーン形成術を施行した1例 Reviewed

市川佳誉, 水谷一輝, 松岡雄治郎, 藤田澄吾子, 伊藤朝広, 岩田真一, 仲川将司, 杉岡憲一, 江原省一, 高木雅彦, 柴田利彦, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 63回 79 - 79 2015.09

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緊急非心臓手術術前に発覚した高度大動脈弁狭窄症に対して順行性大動脈弁バルーン形成術を施行した一例

寺下和範, 水谷一輝, 松岡雄治郎, 仲川将志, 藤田澄吾子, 坂本祥吾, 伊藤朝広, 岩田真一, 杉岡憲一, 高木雅彦, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 63回 908 - 908 2015.09
非弁膜症性心房細動における無症候性脳梗塞のCHADS2スコアに与える影響

河相優, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 63回 1359 - 1359 2015.09
重症大動脈弁狭窄症における僧帽弁輪石灰化の臨床的意義についての検討

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 63回 477 - 477 2015.09
重症大動脈弁狭窄症において、日間血圧変動の増大は大動脈弓部complexプラークの独立した関連因子である

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 63回 1171 - 1171 2015.09
連合弁膜症例に対して、経食道心エコーガイド下で大動脈弁バルーン形成術および僧帽弁交連切開術を同時施行した一例

松岡雄治郎, 水谷一輝, 仲川将志, 藤田澄吾子, 伊藤朝広, 坂本祥吾, 岩田真一, 杉岡憲一, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 63回 344 - 344 2015.09
透析困難症および重症心不全を伴う大動脈弁狭窄症に対して血行動態改善目的に逆行性大動脈弁バルーン形成術を施行した1例

市川佳誉, 水谷一輝, 松岡雄治郎, 藤田澄吾子, 伊藤朝広, 岩田真一, 仲川将司, 杉岡憲一, 江原省一, 高木雅彦, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 63回 79 - 79 2015.09
非弁膜症性心房細動における無症候性脳梗塞発症のメカニズム経食道心エコーによる検討

杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 63回 1244 - 1244 2015.09
ムコ多糖症に合併した大動脈弁・僧帽弁狭窄の心エコー図によるフォロー Reviewed

穂積健之, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 杉岡憲一, 田中あけみ, 葭山稔

(公社)日本超音波医学会, 超音波医学 42 ( Suppl. ) S526 - S526 2015.04（ ISSN:1346-1176 ）

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大動脈弁狭窄症患者における僧帽弁輪石灰化とエコーによる指標との関連 Reviewed

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 葭山稔

(公社)日本超音波医学会, 超音波医学 42 ( Suppl. ) S513 - S513 2015.04（ ISSN:1346-1176 ）

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大動脈弁狭窄症患者における僧帽弁輪石灰化とエコーによる指標との関連

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 葭山稔

超音波医学 42 ( Suppl. ) S513 - S513 2015.04（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
ムコ多糖症に合併した大動脈弁・僧帽弁狭窄の心エコー図によるフォロー

穂積健之, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 杉岡憲一, 田中あけみ, 葭山稔

超音波医学 42 ( Suppl. ) S526 - S526 2015.04（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
非弁膜症性心房細動における大動脈プラークと心不全との関連経食道心エコー図による検討 Reviewed

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 花谷彰久, 成子隆彦, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 62回 P - 492 2014.09

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非弁膜症性心房細動例におけるCHADS2スコアと大動脈complexプラークとの関連 Reviewed

杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 花谷彰久, 仲川将志, 高木雅彦, 成子隆彦, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会学術集会抄録 62回 P - 488 2014.09

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Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
非弁膜症性心房細動における大動脈プラークと心不全との関連経食道心エコー図による検討

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 花谷彰久, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 62回 P - 492 2014.09
非弁膜症性心房細動例におけるCHADS2スコアと大動脈complexプラークとの関連

杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 花谷彰久, 仲川将志, 高木雅彦, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 62回 P - 488 2014.09
重症大動脈弁狭窄症における日間血圧変動と大動脈弓部プラークとの関連 Reviewed

岩田真一, 杉岡憲一, 松村嘉起, 藤田澄吾子, 伊藤朝広, 穂積健之, 北田諒子, 花谷彰久, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 8 ( Suppl.I ) 328 - 328 2013.09（ ISSN:1882-4501 ）

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頸動脈エコーにより大動脈プラークは予測可能か? 頸動脈エコーと経食道心エコーとの比較検討 Reviewed

伊藤朝広, 杉岡憲一, 岩田真一, 松村嘉起, 藤田澄吾子, 花谷彰久, 穂積健之, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 8 ( Suppl.I ) 509 - 509 2013.09（ ISSN:1882-4501 ）

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非弁膜症性心房細動例における大動脈プラークの頻度と関連因子について経食道心エコーによる検討 Reviewed

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 穂積健之, 花谷彰久, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 8 ( Suppl.I ) 509 - 509 2013.09（ ISSN:1882-4501 ）

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非弁膜症性心房細動における経食道心エコーによる大動脈プラーク検索の意義 CHA2DS2-VAScスコアへの影響 Reviewed

山下智子, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 8 ( Suppl.I ) 509 - 509 2013.09（ ISSN:1882-4501 ）

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Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
重症大動脈弁狭窄症における日間血圧変動と大動脈弓部プラークとの関連

岩田真一, 杉岡憲一, 松村嘉起, 藤田澄吾子, 伊藤朝広, 穂積健之, 北田諒子, 花谷彰久, 葭山稔

日本心臓病学会誌 8 ( Suppl.I ) 328 - 328 2013.09（ ISSN:1882-4501 ）
非弁膜症性心房細動における経食道心エコーによる大動脈プラーク検索の意義 CHA2DS2-VAScスコアへの影響

山下智子, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会誌 8 ( Suppl.I ) 509 - 509 2013.09（ ISSN:1882-4501 ）
非弁膜症性心房細動例における大動脈プラークの頻度と関連因子について経食道心エコーによる検討

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 穂積健之, 花谷彰久, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会誌 8 ( Suppl.I ) 509 - 509 2013.09（ ISSN:1882-4501 ）
頸動脈エコーにより大動脈プラークは予測可能か? 頸動脈エコーと経食道心エコーとの比較検討

伊藤朝広, 杉岡憲一, 岩田真一, 松村嘉起, 藤田澄吾子, 花谷彰久, 穂積健之, 葭山稔

日本心臓病学会誌 8 ( Suppl.I ) 509 - 509 2013.09（ ISSN:1882-4501 ）
慢性腎臓病と大動脈プラークとの関連近位胸部大動脈と遠位胸部大動脈との比較検討 Reviewed

松村嘉起, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 穂積健之, 末廣茂文, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 7 ( Suppl.I ) 277 - 277 2012.08（ ISSN:1882-4501 ）

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大動脈弁狭窄症における冠動脈疾患合併と大動脈弓部プラークとの関連経食道心エコー図による検討 Reviewed

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 7 ( Suppl.I ) 277 - 277 2012.08（ ISSN:1882-4501 ）

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大動脈弁狭窄症における近位胸部大動脈の形態的変化についての検討三尖弁と二尖弁大動脈弁狭窄症の比較 Reviewed

藤田澄吾子, 杉岡憲一, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 7 ( Suppl.I ) 277 - 277 2012.08（ ISSN:1882-4501 ）

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慢性腎臓病と大動脈プラークとの関連近位胸部大動脈と遠位胸部大動脈との比較検討

松村嘉起, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 7 ( Suppl.I ) 277 - 277 2012.08（ ISSN:1882-4501 ）
大動脈弁狭窄症における近位胸部大動脈の形態的変化についての検討三尖弁と二尖弁大動脈弁狭窄症の比較

藤田澄吾子, 杉岡憲一, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 7 ( Suppl.I ) 277 - 277 2012.08（ ISSN:1882-4501 ）
大動脈弁狭窄症における冠動脈疾患合併と大動脈弓部プラークとの関連経食道心エコー図による検討

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 7 ( Suppl.I ) 277 - 277 2012.08（ ISSN:1882-4501 ）
弁膜症の診断と治療重症大動脈弁狭窄症における経食道心エコーによる大動脈弓部プラークの評価について Reviewed

杉岡憲一, 穂積健之, 松村嘉起, 伊藤朝広, 葭山稔

(公社)日本超音波医学会　超音波医学 39 ( Suppl. ) S189 - S189 2012.04（ ISSN:1346-1176 ）

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弁膜症の診断と治療重症大動脈弁狭窄症における経食道心エコーによる大動脈弓部プラークの評価について

杉岡憲一, 穂積健之, 松村嘉起, 伊藤朝広, 葭山稔

超音波医学 39 ( Suppl. ) S189 - S189 2012.04（ ISSN:1346-1176 ）（ eISSN:1881-9311 ）
左房に限局するガリウムの異常集積と,全周性左房内膜肥厚を認めた発作性心房細動の一例

柴田敦, 山崎貴紀, 伊藤朝広, 岩田真一, 松村嘉起, 江原省一, 花谷彰久, 島田健永, 葭山稔

日本循環器学会近畿地方会(Web) 114th 2012

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J-GLOBAL
慢性腎臓病は大動脈弓プラークの関連因子である経食道心エコー図を用いた検討 Reviewed

松村嘉起, 杉岡憲一, 穂積健之, 藤田澄吾子, 伊藤朝広, 高木雅彦, 水谷一輝, 成子隆彦, 上田真喜子, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 6 ( Suppl.I ) 398 - 398 2011.08（ ISSN:1882-4501 ）

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組織ドップラー法と二次元スペックルトラッキング法による左室壁運動評価の比較 Reviewed

森下陽子, 大倉宏之, 坂口海雲, 伊藤朝広, 片岡亨, 松下未来, 田村小枝, 山辺梓, 中村恵, 高田裕子, 清水啓子

(一社)日本心臓病学会　日本心臓病学会誌 6 ( Suppl.I ) 382 - 382 2011.08（ ISSN:1882-4501 ）

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リアルタイム3次元経食道心エコー図による大動脈弓プラークの評価についての検討 Reviewed

伊藤朝広, 杉岡憲一, 松村嘉起, 藤田澄吾子, 高木雅彦, 穂積健之, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 6 ( Suppl.I ) 311 - 311 2011.08（ ISSN:1882-4501 ）

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組織ドップラー法と二次元スペックルトラッキング法による左室壁運動評価の比較

森下陽子, 大倉宏之, 坂口海雲, 伊藤朝広, 片岡亨, 松下未来, 田村小枝, 山辺梓, 中村恵, 高田裕子, 清水啓子

日本心臓病学会誌 6 ( Suppl.I ) 382 - 382 2011.08（ ISSN:1882-4501 ）
大動脈弁狭窄症における大動脈弓complexプラークと脳梗塞発症との関連経食道心エコー図による検討 Reviewed

吉山智貴, 杉岡憲一, 穂積健之, 松村嘉起, 藤田澄吾子, 伊藤朝広, 水谷一輝, 成子隆彦, 上田真喜子, 末廣茂文, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 6 ( Suppl.I ) 348 - 348 2011.08（ ISSN:1882-4501 ）

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大動脈弁狭窄と大動脈弓プラークとの関連経食道心エコー図による検討 Reviewed

藤田澄吾子, 杉岡憲一, 穂積健之, 伊藤朝広, 松村嘉起, 成子隆彦, 上田真喜子, 河瀬吉雄, 西本正紀, 末廣茂文, 葭山稔

(一社)日本心臓病学会　日本心臓病学会誌 6 ( Suppl.I ) 272 - 272 2011.08（ ISSN:1882-4501 ）

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リアルタイム3次元経食道心エコー図による大動脈弓プラークの評価についての検討

伊藤朝広, 杉岡憲一, 松村嘉起, 藤田澄吾子, 高木雅彦, 穂積健之, 葭山稔

日本心臓病学会誌 6 ( Suppl.I ) 311 - 311 2011.08（ ISSN:1882-4501 ）
慢性腎臓病は大動脈弓プラークの関連因子である経食道心エコー図を用いた検討

松村嘉起, 杉岡憲一, 穂積健之, 藤田澄吾子, 伊藤朝広, 高木雅彦, 水谷一輝, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会誌 6 ( Suppl.I ) 398 - 398 2011.08（ ISSN:1882-4501 ）
大動脈弁狭窄症における大動脈弓complexプラークと脳梗塞発症との関連経食道心エコー図による検討

吉山智貴, 杉岡憲一, 穂積健之, 松村嘉起, 藤田澄吾子, 伊藤朝広, 水谷一輝, 成子隆彦, 上田真喜子, 末廣茂文, 葭山稔

日本心臓病学会誌 6 ( Suppl.I ) 348 - 348 2011.08（ ISSN:1882-4501 ）
大動脈弁狭窄と大動脈弓プラークとの関連経食道心エコー図による検討

藤田澄吾子, 杉岡憲一, 穂積健之, 伊藤朝広, 松村嘉起, 成子隆彦, 上田真喜子, 河瀬吉雄, 西本正紀, 末廣茂文, 葭山稔

日本心臓病学会誌 6 ( Suppl.I ) 272 - 272 2011.08（ ISSN:1882-4501 ）

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Presentations

夜間血圧、夜間心拍と心血管疾患患者の予後予測に関する検討

キム・アンドリュー・ティー , 伊藤朝広, 伊藤文花, 小川真奈, 北田諒子, 石川世良, 岩田真一, 泉家康宏, 福田大受

日本心臓病学会学術集会抄録 2022.09 (一社)日本心臓病学会
24時間自由行動下血圧測定での血圧変動性と心房細動カテーテルアブレーション後の再発に関する検討

伊藤文花, 伊藤朝広, キム・アンドリュー・ティー , 小川真奈, 北田諒子, 石川世良, 岩田真一, 泉家康宏, 福田大受

日本心臓病学会学術集会抄録 2022.09 (一社)日本心臓病学会
駆出率が低下した心不全患者において夜間平均収縮期血圧の低下は心血管死亡率と関連する(Lower Nocturnal Systolic Blood Pressure is Associated with Cardiovascular Mortality in Heart Failure with Reduced Ejection Fraction Patents)

Kim Andrew T., Ito Asahiro, Ito Ayaka, Ogawa Mana, Kitada Ryoko, Ishikawa Sera, Iwata Shinichi, Izumiya Yasuhiro

日本循環器学会学術集会抄録集 2022.03 (一社)日本循環器学会
夜間心拍数の増加は心血管疾患患者の予後予測因子である(Higher Nighttime Heart Rate is Prognostic Predictor in Patients with Cardiovascular Diseases)

Kim Andrew T., Ito Asahiro, Ito Ayaka, Ogawa Mana, Kitada Ryoko, Ishikawa Sera, Iwata Shinichi, Izumiya Yasuhiro

日本循環器学会学術集会抄録集 2022.03 (一社)日本循環器学会
基本チェックリストは経カテーテル的大動脈弁置換術施行患者の予後予測に有用である(Kihon Checklist is Useful for Predicting Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation)

岡井主, 泉家康宏, 呉裕介, 清水将史, 八尋亮介, 山口智大, 小川真奈, 柴田敦, 伊藤朝広, 高橋洋介, 江原省一, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 2022.03 (一社)日本循環器学会
収縮期血圧の変動の大きさはカテーテルアブレーション後の心房細動再発を予測する(Greater Systolic Blood Pressure Variability Predicts the Recurrence after Atrial Fibrillation Catheter Ablation)

Ito Ayaka, Ito Asahiro, Toyoda Natsumi, Yanagishita Tomoya, Kim Andrew T., Nakatsuji Kenichi, Ogawa Mana, Ishikawa Sera, Yoshiyama Tomotaka, Iwata Shinichi, Izumiya Yasuhiro

日本循環器学会学術集会抄録集 2022.03 (一社)日本循環器学会
ペーシングにより誘発される心筋症のリスク因子　リードの位置からの洞察(Risk Factors of Pacing-Induced Cardiomyopathy: Insights from Lead Position)

吉山智貴, 占野賢司, 豊田なつみ, 柳下知哉, 田村尚大, 中逵賢一, 林雄介, 伊藤朝広, 泉家康宏, 阿部幸雄, 江原省一, 成子隆彦

日本循環器学会学術集会抄録集 2022.03 (一社)日本循環器学会
僧帽弁輪石灰化に付着した疣腫を認めた感染性心内膜炎の一例

塩路夏海, 安保浩二, 草壁仁美, 堂前有加, 橋本深香, 小川真奈, Kim Andrew T., 伊藤文花, 石川世良, 伊藤朝広

日本超音波医学会関西地方会学術集会 2021.10 (公社)日本超音波医学会-関西地方会
重症大動脈弁狭窄症患者における夜間血圧と僧帽弁輪石灰化の関連　multidetector-row CTからの知見(Nighttime Blood Pressure is Associated with Mitral Annular Calcification in Patients with Severe Aortic Stenosis: Insights from Multidetector-Row Computed Tomography)

Andrew Kim, 岩田真一, 田村聡一郎, 伊藤文花, 小川真奈, 能仁信一, 石川世良, 伊藤朝広, 泉家康宏, 高橋洋介, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 2021.03 (一社)日本循環器学会
三尖弁輪部と弁尖の伸縮性は機能性三尖弁閉鎖不全症と関連する　3D経食道心エコー図からの洞察(Tricuspid Annular Area and Leaflets Stretch are Associated with Functional Tricuspid Regurgitation: Insights from Three-Dimensional Transesophageal Echocardiography)

伊藤文花, 伊藤朝広, 岩田真一, Kim Andrew T., 小川真奈, 能仁信一, 石川世良, 泉家康宏, 高橋洋介, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 2021.03 (一社)日本循環器学会
シスタチンCから算出した腎機能とTAVI後の予後の検討

岡井主, 水谷一輝, 八尋亮介, 山口智大, 小川真奈, 能仁信一, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2021.02 (一社)日本心血管インターベンション治療学会
Faster Nighttime Heart Rate is Associated with Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation(和訳中) Domestic conference

T.Kim Andrew, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Matsuo Masanori, Yoshiyama Tomotaka, Nonin Shinichi, Ishikawa Sera, Izumiya Yasuhiro, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会

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非弁膜症性心房細動患者における夜間心拍数の上昇は無症候性脳梗塞と関連している(Faster Nighttime Heart Rate is Associated with Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation)

Kim Andrew T., Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Matsuo Masanori, Yoshiyama Tomotaka, Nonin Shinichi, Ishikawa Sera, Izumiya Yasuhiro, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会
重症大動脈弁狭窄症患者における夜間血圧の上昇と僧帽弁輪石灰化との関連(Greater Nocturnal Blood Pressure is Associated with Mitral Annular Calcification in Patients with Severe Aortic Stenosis)

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Kim Andrew, Nonin Shinichi, Mizutani Kazuki, Izumiya Yasuhiro, Takahashi Yosuke, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会
経カテーテル大動脈弁置換術後1年のフォローアップで無症候性脳梗塞が認知機能低下に及ぼす臨床的影響(The Clinical Impact of Silent Cerebral Infarction for Cognitive Decline at One-Year Follow-up after Transcatheter Aortic Valve Replacement)

Ogawa Mana, Mizutani Kazuki, Yamaguchi Tomohiro, Okai Tsukasa, Nonin Shinichi, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Izumiya Yasuhiro, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会
Tricuspid Annular Area and Septum Leaflet Stretch are Associated with Functional Tricuspid Regurgitation: Insights from Three-Dimensional Transesophageal Echocardiography(和訳中) Domestic conference

Ito Asahiro, Iwata Shinichi, Kim Andrew, Tamura Soichiro, Nonin Shinichi, Mizutani Kazuki, Izumiya Yasuhiro, Takahashi Yosuke, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会

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The Clinical Impact of Silent Cerebral Infarction for Cognitive Decline at One-Year Follow-up after Transcatheter Aortic Valve Replacement(和訳中) Domestic conference

Ogawa Mana, Mizutani Kazuki, Yamaguchi Tomohiro, Okai Tsukasa, Nonin Shinichi, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Izumiya Yasuhiro, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会

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Greater Nocturnal Blood Pressure is Associated with Mitral Annular Calcification in Patients with Severe Aortic Stenosis(和訳中) Domestic conference

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Kim Andrew, Nonin Shinichi, Mizutani Kazuki, Izumiya Yasuhiro, Takahashi Yosuke, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会

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三尖弁輪面積と中隔弁の柔軟性は機能性三尖弁逆流症と関連している　3D経食道心エコー図検査からの洞察(Tricuspid Annular Area and Septum Leaflet Stretch are Associated with Functional Tricuspid Regurgitation: Insights from Three-Dimensional Transesophageal Echocardiography)

Ito Asahiro, Iwata Shinichi, Kim Andrew, Tamura Soichiro, Nonin Shinichi, Mizutani Kazuki, Izumiya Yasuhiro, Takahashi Yosuke, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2020.07 (一社)日本循環器学会
Complication & Bailout of TAVI(Case-Based)1　自己拡張弁導入の際に自己弁尖が左室側に反転し、急性大動脈弁閉鎖不全を来たした1例　どのようにbail-outしますか? Domestic conference

水谷一輝, 山口智大, 小川真奈, 岡井主, 伊藤朝広, 岩田真一, 泉家康宏, 葭山稔

日本心血管インターベンション治療学会抄録集 2019.09 (一社)日本心血管インターベンション治療学会

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冠動脈3枝病変、下大静脈欠損を伴うASDを合併したsevere ASに対して、カテーテル治療で完遂し得た1例 Domestic conference

山本崇之, 岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2019.09 (一社)日本心血管インターベンション治療学会

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TAVI後の凝固線溶系因子の上昇に関する予測因子の検討　抗凝固療法が有効? Domestic conference

岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2019.09 (一社)日本心血管インターベンション治療学会

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冠動脈3枝病変、下大静脈欠損を伴うASDを合併したsevere ASに対して、カテーテル治療で完遂し得た1例

山本崇之, 岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2019.09 (一社)日本心血管インターベンション治療学会
TAVI後の凝固線溶系因子の上昇に関する予測因子の検討　抗凝固療法が有効?

岡井主, 水谷一輝, 山口智大, 小川真奈, 梶尾啓子, 伊藤朝広, 岩田真一, 高橋洋介, 泉家康宏, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2019.09 (一社)日本心血管インターベンション治療学会
Complication & Bailout of TAVI(Case-Based)1　自己拡張弁導入の際に自己弁尖が左室側に反転し、急性大動脈弁閉鎖不全を来たした1例　どのようにbail-outしますか?

水谷一輝, 山口智大, 小川真奈, 岡井主, 伊藤朝広, 岩田真一, 泉家康宏, 葭山稔

日本心血管インターベンション治療学会抄録集 2019.09 (一社)日本心血管インターベンション治療学会
発作性と持続性の非弁膜症性心房細動患者における無症候性脳梗塞の有病率およびリスク因子の差(Differences in Prevalence and Risk Factors of Silent Brain Infarction between Patients with Paroxysmal and Persistentnonvalvular Atrial Fibrillation) Domestic conference

石川世良, 岩田真一, 伊藤朝広, 田村聡一郎, 河相優, 吉山智貴, 辰巳裕亮, 土井淳史, 泉家康宏, 葭山稔

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会

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腎機能障害とCHA2DS2-VAScスコアは重度大動脈弁狭窄患者の無症候性脳梗塞と関連している(Renal Impairment and CHA2DS2-VASc Score are Associated with Silent Brain Infarction in Patients with Severe Aortic Stenosis) Domestic conference

Tamura Soichiro, Iwata Shinichi, Kawai Yu, Ishikawa Sera, Ito Asahiro, Mizutani Kazuki, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会

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経カテーテル大動脈弁置換術後の経過観察期におけるD-dimerレベル上昇の予測因子　経口抗凝固薬療法はより優れているか(Predictors of Increased D-dimer Level at Follow-up Period after Transcatheter Aortic Valve Replacement: Is Oral Anticoagulation Therapy Better?) Domestic conference

Okai Tsukasa, Mizutani Kazuki, Yamaguchi Tomohiro, Nakao Mana, Kajio Keiko, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Izumiya Yasuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会

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経カテーテル大動脈弁置換術後の弁周囲漏出のグレードの中期改善の予測因子(Predictors of Mid-term Improvement of Paravalvular Leakage Grade after Transcatheter Aortic Valve Replacement) Domestic conference

Nakao Mana, Mizutani Kazuki, Yamaguchi Tomohiro, Okai Tsukasa, Kajio Keiko, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Izumiya Yasuhiro, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会

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冠動脈洞におけるB-type natriuretic peptideおよびtroponin Tの上昇はTAVR後の左室逆リモデリングと関連している(Elevation of B-type Natriuretic Peptide and Troponin T in Coronary Sinus is Associated with Left Ventricular Reverse Remodeling after TAVR) Domestic conference

Kajio Keiko, Mizutani Kazuki, Yamaguchi Tomohiro, Nakao Mana, Okai Tsukasa, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Izumiya Yasuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会

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腎機能障害とCHA2DS2-VAScスコアは重度大動脈弁狭窄患者の無症候性脳梗塞と関連している(Renal Impairment and CHA2DS2-VASc Score are Associated with Silent Brain Infarction in Patients with Severe Aortic Stenosis)

Tamura Soichiro, Iwata Shinichi, Kawai Yu, Ishikawa Sera, Ito Asahiro, Mizutani Kazuki, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会
経カテーテル大動脈弁置換術後の経過観察期におけるD-dimerレベル上昇の予測因子　経口抗凝固薬療法はより優れているか(Predictors of Increased D-dimer Level at Follow-up Period after Transcatheter Aortic Valve Replacement: Is Oral Anticoagulation Therapy Better?)

Okai Tsukasa, Mizutani Kazuki, Yamaguchi Tomohiro, Nakao Mana, Kajio Keiko, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Izumiya Yasuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会
経カテーテル大動脈弁置換術後の弁周囲漏出のグレードの中期改善の予測因子(Predictors of Mid-term Improvement of Paravalvular Leakage Grade after Transcatheter Aortic Valve Replacement)

Nakao Mana, Mizutani Kazuki, Yamaguchi Tomohiro, Okai Tsukasa, Kajio Keiko, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Izumiya Yasuhiro, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会
発作性と持続性の非弁膜症性心房細動患者における無症候性脳梗塞の有病率およびリスク因子の差(Differences in Prevalence and Risk Factors of Silent Brain Infarction between Patients with Paroxysmal and Persistentnonvalvular Atrial Fibrillation)

石川世良, 岩田真一, 伊藤朝広, 田村聡一郎, 河相優, 吉山智貴, 辰巳裕亮, 土井淳史, 泉家康宏, 葭山稔

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会
左房拡大は経大腿による経カテーテル大動脈弁置換術後のB-type natriuretic peptide値の改善不良と関連する(Left Atrial Enlargement is Associated with Poor Improvement of B-type Natriuretic Peptide Levels after Transfemoral Transcatheter Aortic Valve Replacement) Domestic conference

Ito Asahiro, Iwata Shinichi, Mizutani Kazuki, Nakao Mana, Okai Tsukasa, Takahashi Yosuke, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会

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左房拡大は経大腿による経カテーテル大動脈弁置換術後のB-type natriuretic peptide値の改善不良と関連する(Left Atrial Enlargement is Associated with Poor Improvement of B-type Natriuretic Peptide Levels after Transfemoral Transcatheter Aortic Valve Replacement)

Ito Asahiro, Iwata Shinichi, Mizutani Kazuki, Nakao Mana, Okai Tsukasa, Takahashi Yosuke, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会
冠動脈洞におけるB-type natriuretic peptideおよびtroponin Tの上昇はTAVR後の左室逆リモデリングと関連している(Elevation of B-type Natriuretic Peptide and Troponin T in Coronary Sinus is Associated with Left Ventricular Reverse Remodeling after TAVR)

Kajio Keiko, Mizutani Kazuki, Yamaguchi Tomohiro, Nakao Mana, Okai Tsukasa, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Izumiya Yasuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2019.03 (一社)日本循環器学会
非弁膜症性心房細動患者における組織ドプラ法による左室拡張能評価と無症候性脳梗塞の関連性 Domestic conference

石川世良, 杉岡憲一, 坂本真一, 藤田澄吾子, 伊藤朝広, 則岡直樹, 岩田真一, 仲川将志, 高木雅彦, 三木幸雄, 上田真喜子, 葭山稔

大阪市医学会雑誌 2018.12 大阪市医学会

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非弁膜症性心房細動患者における組織ドプラ法による左室拡張能評価と無症候性脳梗塞の関連性

石川世良, 杉岡憲一, 坂本真一, 藤田澄吾子, 伊藤朝広, 則岡直樹, 岩田真一, 仲川将志, 高木雅彦, 三木幸雄, 上田真喜子, 葭山稔

大阪市医学会雑誌 2018.12 大阪市医学会
Left Ventricular Outpouchingを有する重症大動脈弁狭窄症に対して経カテーテル的大動脈弁植え込み術を施行し得た2症例 Domestic conference

梶尾啓子, 水谷一輝, 中尾真奈, 岡井主, 野元陽太, 伊藤朝広, 山崎貴紀, 岩田真一, 紙森公雄, 葭山稔

日本心血管インターベンション治療学会抄録集 2018.08 (一社)日本心血管インターベンション治療学会

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僧帽弁狭窄症のTAVR直後に生じる心不全増悪への関与 Domestic conference

岡井主, 水谷一輝, 中尾真奈, 梶尾啓子, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2018.08 (一社)日本心血管インターベンション治療学会

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Left Ventricular Outpouchingを有する重症大動脈弁狭窄症に対して経カテーテル的大動脈弁植え込み術を施行し得た2症例

梶尾啓子, 水谷一輝, 中尾真奈, 岡井主, 野元陽太, 伊藤朝広, 山崎貴紀, 岩田真一, 紙森公雄, 葭山稔

日本心血管インターベンション治療学会抄録集 2018.08 (一社)日本心血管インターベンション治療学会
僧帽弁狭窄症のTAVR直後に生じる心不全増悪への関与

岡井主, 水谷一輝, 中尾真奈, 梶尾啓子, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2018.08 (一社)日本心血管インターベンション治療学会
経大腿動脈経カテーテル大動脈弁置換術中の血行動態学的に有意な急性僧帽弁逆流を予測する心エコーパラメータ(Echocardiographic Parameters Predicting Acute Hemodynamically Significant Mitral Regurgitation during Transfemoral Transcatheter Aortic Valve Replacement) Domestic conference

Ito Asahiro, Iwata Shinichi, Mizutani Kazuki, Nonin Shinichi, Nishimura Shinsuke, Takahashi Yosuke, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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経カテーテル大動脈弁置換術後の弁周囲逆流の軽減に対する弁輪偏心性と過大サイズ弁配置の影響(The Impact of Annulus Eccentricity and Over-sizing Valve Deployment for Less Paravalvular Leakage after Transcatheter Aortic Valve Replacement) Domestic conference

Nakao Mana, Mizutani Kazuki, Okai Tsukasa, Yoshida Keiko, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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経カテーテル大動脈弁置換直後の心不全増悪に対する弁輪石灰化を伴う僧帽弁狭窄の影響(The Impact of Mitral Stenosis with Annular Calcification for Worsening Heart Failure Just after Transcatheter Aortic Valve Replacement) Domestic conference

Okai Tsukasa, Mizutani Kazuki, Nakao Mana, Kajio Keiko, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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心臓以外の手術前に行うバルーン大動脈弁形成術の有効性　多施設共同レジストリからの知見(The Efficacy of Balloon Aortic Valvuloplasty before Non-cardiac Surgery: Insight from Multi-center Registry) Domestic conference

Ito Ayaka, Mizutani Kazuki, Okai Tsukasa, Yoshida Keiko, Ito Asahiro, Iwata Shinichi, Yoshiyama Minoru, Iwasaki Masamichi, Ito Kazato, Shimada Yoshihisa, Shinke Toshiro

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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重度の大動脈弁狭窄を有する患者において自己拡張型バルブは経カテーテル大動脈弁置換術後にDW-MRIにより検出される高信号のスポットに影響を及ぼす(Self-Expandable Valve Affects High Intensity Spots Detected by DW-MRI after Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis) Domestic conference

吉田啓子, 水谷一輝, 原正彦, 中尾真奈, 岡井主, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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重度大動脈弁狭窄患者において中心脈圧の大幅な変動は大動脈弁のカルシウム量と関連する(Higher Central Pulse Pressure Variability is Associated with Aortic Valve Calcium Volume in Patients with Severe Aortic Stenosis)

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Nishimura Shinsuke, Mizutani Kazuki, Takahashi Yosuke, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
重度大動脈弁狭窄患者においてCHA2DS2-VAScスコアおよび腎機能障害は無症候性脳梗塞と関連する(CHA2DS2-VASc Score and Renal Impairment are Associated with Silent Brain Infarction in Patients with Severe Aortic Stenosis)

Kawai Yu, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kitada Ryoko, Nonin Shinichi, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
重度の大動脈弁狭窄を有する患者において自己拡張型バルブは経カテーテル大動脈弁置換術後にDW-MRIにより検出される高信号のスポットに影響を及ぼす(Self-Expandable Valve Affects High Intensity Spots Detected by DW-MRI after Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis)

吉田啓子, 水谷一輝, 原正彦, 中尾真奈, 岡井主, 西村慎亮, 伊藤朝広, 岩田真一, 高橋洋介, 村上貴志, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
経大腿動脈経カテーテル大動脈弁置換術中の血行動態学的に有意な急性僧帽弁逆流を予測する心エコーパラメータ(Echocardiographic Parameters Predicting Acute Hemodynamically Significant Mitral Regurgitation during Transfemoral Transcatheter Aortic Valve Replacement)

Ito Asahiro, Iwata Shinichi, Mizutani Kazuki, Nonin Shinichi, Nishimura Shinsuke, Takahashi Yosuke, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
経カテーテル大動脈弁置換術後の弁周囲逆流の軽減に対する弁輪偏心性と過大サイズ弁配置の影響(The Impact of Annulus Eccentricity and Over-sizing Valve Deployment for Less Paravalvular Leakage after Transcatheter Aortic Valve Replacement)

Nakao Mana, Mizutani Kazuki, Okai Tsukasa, Yoshida Keiko, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
経カテーテル大動脈弁置換直後の心不全増悪に対する弁輪石灰化を伴う僧帽弁狭窄の影響(The Impact of Mitral Stenosis with Annular Calcification for Worsening Heart Failure Just after Transcatheter Aortic Valve Replacement)

Okai Tsukasa, Mizutani Kazuki, Nakao Mana, Kajio Keiko, Nishimura Shinsuke, Ito Asahiro, Iwata Shinichi, Takahashi Yosuke, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
駆出率低下を伴ううっ血性心不全患者において左室拡大はtolvaptanへの反応性を予測する(Right Ventricular Enlargement Predicts Responsiveness to Tolvaptan in Congestive Heart Failure Patients with Reduced Ejection Fraction) Domestic conference

Nonin Shinichi, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kitada Ryoko, Kawai Yu, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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重度大動脈弁狭窄患者において中心脈圧の大幅な変動は大動脈弁のカルシウム量と関連する(Higher Central Pulse Pressure Variability is Associated with Aortic Valve Calcium Volume in Patients with Severe Aortic Stenosis) Domestic conference

Tamura Soichiro, Iwata Shinichi, Ito Asahiro, Nishimura Shinsuke, Mizutani Kazuki, Takahashi Yosuke, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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重度大動脈弁狭窄患者においてCHA2DS2-VAScスコアおよび腎機能障害は無症候性脳梗塞と関連する(CHA2DS2-VASc Score and Renal Impairment are Associated with Silent Brain Infarction in Patients with Severe Aortic Stenosis) Domestic conference

Kawai Yu, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kitada Ryoko, Nonin Shinichi, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会

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駆出率低下を伴ううっ血性心不全患者において左室拡大はtolvaptanへの反応性を予測する(Right Ventricular Enlargement Predicts Responsiveness to Tolvaptan in Congestive Heart Failure Patients with Reduced Ejection Fraction)

Nonin Shinichi, Iwata Shinichi, Ito Asahiro, Tamura Soichiro, Kitada Ryoko, Kawai Yu, Ishikawa Sera, Doi Atsushi, Hanatani Akihisa, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
心臓以外の手術前に行うバルーン大動脈弁形成術の有効性　多施設共同レジストリからの知見(The Efficacy of Balloon Aortic Valvuloplasty before Non-cardiac Surgery: Insight from Multi-center Registry)

Ito Ayaka, Mizutani Kazuki, Okai Tsukasa, Yoshida Keiko, Ito Asahiro, Iwata Shinichi, Yoshiyama Minoru, Iwasaki Masamichi, Ito Kazato, Shimada Yoshihisa, Shinke Toshiro

日本循環器学会学術集会抄録集 2018.03 (一社)日本循環器学会
新時代のバルーン大動脈弁形成術　経食道心エコーガイドのポイントと手技のtips&tricks Domestic conference

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2017.07 (一社)日本心血管インターベンション治療学会

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新時代のバルーン大動脈弁形成術　経食道心エコーガイドのポイントと手技のtips&tricks

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2017.07 (一社)日本心血管インターベンション治療学会
経カテーテル的大動脈弁置換術中に血行動態破綻を来す急性僧帽弁閉鎖不全症の予測因子 Domestic conference

伊藤朝広, 岩田真一, 水谷一輝, 土井淳史, 花谷彰久, 高橋洋介, 山田徳洪, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会総会プログラム・抄録集 2017.06 日本循環制御医学会

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重症大動脈弁狭窄症患者における3次元経食道心エコーガイド下で施行する順行性大動脈弁バルーン形成術の頻回拡張の安全性と有効性について Domestic conference

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会総会プログラム・抄録集 2017.06 日本循環制御医学会

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重症大動脈弁狭窄症患者における3次元経食道心エコーガイド下で施行する順行性大動脈弁バルーン形成術の頻回拡張の安全性と有効性について

水谷一輝, 原正彦, 伊藤朝広, 岩田真一, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会総会プログラム・抄録集 2017.06 日本循環制御医学会
経カテーテル的大動脈弁置換術中に血行動態破綻を来す急性僧帽弁閉鎖不全症の予測因子

伊藤朝広, 岩田真一, 水谷一輝, 土井淳史, 花谷彰久, 高橋洋介, 山田徳洪, 村上貴志, 柴田利彦, 葭山稔

日本循環制御医学会総会プログラム・抄録集 2017.06 日本循環制御医学会
駆出率が低下しているうっ血性心不全患者において右室拡大はtolvaptanへの反応性を予測する(Right Ventricular Enlargement Predicts Responsiveness to Tolvaptan in Congestive Heart Failure Patients with Reduced Ejection Fraction)

Nonin Shinichi, Iwata Shinichi, Sugioka Kenichi, Tamura Soichiro, Kawai Yu, Fujita Suwako, Ishikawa Sera, Norioka Naoki, Ito Asahiro, Hanatani Akihisa, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会
経大腿動脈アプローチの経カテーテル大動脈弁置換術中の血行動態的に重大な急性僧帽弁逆流に影響する心エコーパラメータ(Echocardiographic Parameters Affecting Hemodynamically Significant Acute Mitral Regurgitation during Transfemoral Transcatheter Aortic Valve Replacement) Domestic conference

Ito Asahiro, Iwata Shinichi, Sugioka Kenichi, Matsuoka Yujiro, Fujita Suwako, Mizutani Kazuki, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会

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非弁膜症性心房細動の患者における無症候性脳梗塞に対する組織ドップラーイメージングによる左室拡張機能の影響(Impact of Left Ventricular Diastolic Function by Tissue Doppler Imaging on Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation) Domestic conference

Ishikawa Sera, Sugioka Kenichi, Iwata Shinichi, Norioka Naoki, Nonin Shinichi, Kawai Yu, Fujita Suwako, Ito Asahiro, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会

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非弁膜症性心房細動の患者における無症候性脳梗塞に対する組織ドップラーイメージングによる左室拡張機能の影響(Impact of Left Ventricular Diastolic Function by Tissue Doppler Imaging on Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation)

Ishikawa Sera, Sugioka Kenichi, Iwata Shinichi, Norioka Naoki, Nonin Shinichi, Kawai Yu, Fujita Suwako, Ito Asahiro, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会
経大腿動脈アプローチの経カテーテル大動脈弁置換術中の血行動態的に重大な急性僧帽弁逆流に影響する心エコーパラメータ(Echocardiographic Parameters Affecting Hemodynamically Significant Acute Mitral Regurgitation during Transfemoral Transcatheter Aortic Valve Replacement)

Ito Asahiro, Iwata Shinichi, Sugioka Kenichi, Matsuoka Yujiro, Fujita Suwako, Mizutani Kazuki, Yamada Tokuhiro, Murakami Takashi, Shibata Toshihiko, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会
夜間の高血圧は重度大動脈弁狭窄患者のB-type natriuretic peptide値と関連する(Higher Nocturnal Blood Pressure is Associated with B-Type Natriuretic Peptide Levels in Patients with Severe Aortic Stenosis) Domestic conference

Tamura Soichiro, Iwata Shinichi, Sugioka Kenichi, Kawai Yu, Fujita Suwako, Nonin Shinichi, Ishikawa Sera, Norioka Naoki, Ito Asahiro, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会

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より安全な心血管インターベンションを目指して　メディカルスタッフに求めたい安全のための技量 Domestic conference

水谷一輝, 伊藤朝広, 高尾由範, 西村慎亮, 岩田真一, 高橋洋介, 村上貴志, 山田徳洪, 市田隆雄, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会

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駆出率の保たれた重度大動脈弁狭窄患者では高い中心脈圧が推定糸球体濾過率と関連する(Higher Central Pulse Pressure is Associated with Estimated-Glomerular Filtration Rate in Patients with Severe Aortic Stenosis and Preserved Ejection Fraction) Domestic conference

Norioka Naoki, Iwata Shinichi, Sugioka Kenichi, Tamura Soichiro, Kawai Yu, Fujita Suwako, Nonin Shinichi, Ishikawa Sera, Ito Asahiro, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会

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駆出率が低下しているうっ血性心不全患者において右室拡大はtolvaptanへの反応性を予測する(Right Ventricular Enlargement Predicts Responsiveness to Tolvaptan in Congestive Heart Failure Patients with Reduced Ejection Fraction) Domestic conference

Nonin Shinichi, Iwata Shinichi, Sugioka Kenichi, Tamura Soichiro, Kawai Yu, Fujita Suwako, Ishikawa Sera, Norioka Naoki, Ito Asahiro, Hanatani Akihisa, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会

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駆出率の保たれた重度大動脈弁狭窄患者では高い中心脈圧が推定糸球体濾過率と関連する(Higher Central Pulse Pressure is Associated with Estimated-Glomerular Filtration Rate in Patients with Severe Aortic Stenosis and Preserved Ejection Fraction)

Norioka Naoki, Iwata Shinichi, Sugioka Kenichi, Tamura Soichiro, Kawai Yu, Fujita Suwako, Nonin Shinichi, Ishikawa Sera, Ito Asahiro, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会
夜間の高血圧は重度大動脈弁狭窄患者のB-type natriuretic peptide値と関連する(Higher Nocturnal Blood Pressure is Associated with B-Type Natriuretic Peptide Levels in Patients with Severe Aortic Stenosis)

Tamura Soichiro, Iwata Shinichi, Sugioka Kenichi, Kawai Yu, Fujita Suwako, Nonin Shinichi, Ishikawa Sera, Norioka Naoki, Ito Asahiro, Yoshiyama Minoru

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会
より安全な心血管インターベンションを目指して　メディカルスタッフに求めたい安全のための技量

水谷一輝, 伊藤朝広, 高尾由範, 西村慎亮, 岩田真一, 高橋洋介, 村上貴志, 山田徳洪, 市田隆雄, 柴田利彦, 葭山稔

日本循環器学会学術集会抄録集 2017.03 (一社)日本循環器学会
重症大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討　三尖弁と二尖弁大動脈弁狭窄症の比較 Domestic conference

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2016.09 (一社)日本心臓病学会

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非弁膜症性心房細動における無症候性脳梗塞と左室充満圧(E/e')との関連

石川世良, 杉岡憲一, 岩田真一, 伊藤朝広, 河相優, 能仁信一, 藤田澄吾子, 則岡直樹, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2016.09 (一社)日本心臓病学会
重症大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討　三尖弁と二尖弁大動脈弁狭窄症の比較

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2016.09 (一社)日本心臓病学会
冠動脈疾患患者において、頸動脈plaque surface irregularityは心血管二次イベントの予測因子である Domestic conference

能仁信一, 岩田真一, 杉岡憲一, 河相優, 藤田澄吾子, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2016.09 (一社)日本心臓病学会

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非弁膜症性心房細動における無症候性脳梗塞と左室充満圧(E/e')との関連 Domestic conference

石川世良, 杉岡憲一, 岩田真一, 伊藤朝広, 河相優, 能仁信一, 藤田澄吾子, 則岡直樹, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2016.09 (一社)日本心臓病学会

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冠動脈疾患患者において、頸動脈plaque surface irregularityは心血管二次イベントの予測因子である

能仁信一, 岩田真一, 杉岡憲一, 河相優, 藤田澄吾子, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2016.09 (一社)日本心臓病学会
経食道心エコー図ガイド下による順行性大動脈弁バルーン拡張術の有効性と安全性について Domestic conference

水谷一輝, 松岡雄治郎, 阪本勇也, 伊藤朝広, 岩田真一, 仲川将志, 白井伸幸, 杉岡憲一, 高木雅彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2016.07 (一社)日本心血管インターベンション治療学会

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経食道心エコーガイド下で弁輪破裂を回避し得たantegrade BAVの一例 Domestic conference

松岡雄治郎, 水谷一輝, 伊藤朝広, 岩田真一, 仲川将志, 杉岡憲一, 村上貴志, 細野光治, 高木雅彦, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2016.07 (一社)日本心血管インターベンション治療学会

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経食道心エコーガイド下で弁輪破裂を回避し得たantegrade BAVの一例

松岡雄治郎, 水谷一輝, 伊藤朝広, 岩田真一, 仲川将志, 杉岡憲一, 村上貴志, 細野光治, 高木雅彦, 柴田利彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2016.07 (一社)日本心血管インターベンション治療学会
経食道心エコー図ガイド下による順行性大動脈弁バルーン拡張術の有効性と安全性について

水谷一輝, 松岡雄治郎, 阪本勇也, 伊藤朝広, 岩田真一, 仲川将志, 白井伸幸, 杉岡憲一, 高木雅彦, 葭山稔

日本心血管インターベンション治療学会抄録集 2016.07 (一社)日本心血管インターベンション治療学会
大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討 Domestic conference

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

日本動脈硬化学会総会プログラム・抄録集 2016.06 (一社)日本動脈硬化学会

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Presentation type：Oral presentation (general)
大動脈弁狭窄症における近位胸部大動脈の動脈硬化についての検討

藤田澄吾子, 杉岡憲一, 岩田真一, 河相優, 能仁信一, 石川世良, 則岡直樹, 伊藤朝広, 仲川将志, 上田真喜子, 葭山稔

日本動脈硬化学会総会プログラム・抄録集 2016.06 (一社)日本動脈硬化学会
結節性紅斑との鑑別を要した感染性心内膜炎による敗血疹の1例 Domestic conference

真鍋麻里奈, 今西久幹, 大迫順子, 梅田桜子, 伊藤朝広, 安水大介, 葭山稔, 鶴田大輔

日本皮膚科学会雑誌 2016.05 (公社)日本皮膚科学会

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結節性紅斑との鑑別を要した感染性心内膜炎による敗血疹の1例

真鍋麻里奈, 今西久幹, 大迫順子, 梅田桜子, 伊藤朝広, 安水大介, 葭山稔, 鶴田大輔

日本皮膚科学会雑誌 2016.05 (公社)日本皮膚科学会
大動脈弓部動脈硬化性穿通性潰瘍と非連続性に限局性解離を合併した一例 Domestic conference

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 石川世良, 安保浩二, 藤岡一也, 葭山稔

超音波医学 2016.04 (公社)日本超音波医学会

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左室駆出率が保持された心房細動患者において、夜間血圧変動性が左房拡大に与える影響 Domestic conference

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 花谷彰久, 高木雅彦, 葭山稔

超音波医学 2016.04 (公社)日本超音波医学会

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大動脈弓部動脈硬化性穿通性潰瘍と非連続性に限局性解離を合併した一例

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 石川世良, 安保浩二, 藤岡一也, 葭山稔

超音波医学 2016.04 (公社)日本超音波医学会
左室駆出率が保持された心房細動患者において、夜間血圧変動性が左房拡大に与える影響

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 花谷彰久, 高木雅彦, 葭山稔

超音波医学 2016.04 (公社)日本超音波医学会
駆出率が低下した慢性心不全患者における夜間高血圧はbrain natriuretic peptide値と関連する(Higher Nocturnal Blood Pressure is Associated with Brain Natriuretic Peptide Levels in Chronic Heart Failure Patients with Reduced Ejection Fraction)

Kitada Ryoko, Iwata Shinichi, Hanatani Akihisa, Norioka Naoki, Kaga Suwako, Ito Asahiro, Sugioka Kenichi, Takagi Masahiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会
石灰化頸動脈プラークは冠動脈疾患患者の2次性心血管イベントが予測される(Calcified Carotid Plaques Predict Secondary Cardiovascular Events in Patients with Coronary Artery Disease) Domestic conference

Nonin Shinichi, Iwata Shinichi, Sugioka Kenichi, Fujita Suwako, Norioka Naoki, Ito Asahiro, Nakagawa Masashi, Hanatani Akihisa, Takagi Masahiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会

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心不全発症を契機にミトコンドリア心筋症の診断に至った左室肥大の一例 Domestic conference

市川佳誉, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 安保浩二, 藤岡一也, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会

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非弁膜症性心房細動患者において無症候性脳梗塞を予測する左心耳血流速度(Left Atrial Appendage Flow Velocity for the Prediction of Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation) Domestic conference

Ishikawa Sera, Sugioka Kenichi, Iwata Shinichi, Norioka Naoki, Kawai Yu, Kaga Suwako, Ito Asahiro, Hanatani Akihisa, Tatsumi Hiroaki, Doi Atsushi, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会

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非弁膜症性心房細動患者における無症候性脳梗塞とCHADS2スコアおよび経食道心エコー所見との関連性(Relation of Silent Brain Infarction to CHADS2 Score and Transesophageal Echocardiographic Findings in Patients with Nonvalvular Atrial Fibrillation)

Kawai Yu, Sugioka Kenichi, Iwata Shinichi, Ishikawa Sera, Norioka Naoki, Fujita Suwako, Ito Asahiro, Hanatani Akihisa, Tatsumi Hiroaki, Doi Atsushi, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会
非弁膜症性心房細動患者において無症候性脳梗塞を予測する左心耳血流速度(Left Atrial Appendage Flow Velocity for the Prediction of Silent Brain Infarction in Patients with Nonvalvular Atrial Fibrillation)

Ishikawa Sera, Sugioka Kenichi, Iwata Shinichi, Norioka Naoki, Kawai Yu, Kaga Suwako, Ito Asahiro, Hanatani Akihisa, Tatsumi Hiroaki, Doi Atsushi, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会
石灰化頸動脈プラークは冠動脈疾患患者の2次性心血管イベントが予測される(Calcified Carotid Plaques Predict Secondary Cardiovascular Events in Patients with Coronary Artery Disease)

Nonin Shinichi, Iwata Shinichi, Sugioka Kenichi, Fujita Suwako, Norioka Naoki, Ito Asahiro, Nakagawa Masashi, Hanatani Akihisa, Takagi Masahiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会
心エコーにて限局性の心筋炎が疑われた持続性心室頻拍の一例 Domestic conference

寺下和範, 杉岡憲一, 岩田真一, 河相優, 藤田澄吾子, 伊藤朝広, 安保浩二, 藤岡一也, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会

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完全房室ブロックをきたした心臓原発悪性リンパ腫の一例 Domestic conference

武坂絢, 杉岡憲一, 岩田真一, 伊藤朝広, 藤田澄吾子, 阿保浩二, 藤岡一也, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会

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夜間血圧の大きな変動は、駆出率が保持された心房細動患者における左室肥大と関係している(Greater Nighttime Blood Pressure Variability is Associated with Left Atrial Enlargement in Atrial Fibrillation Patients with Preserved Ejection Fraction) Domestic conference

Norioka Naoki, Iwata Shinichi, Sugioka Kenichi, Kaga Suwako, Ito Asahiro, Hanatani Akihisa, Takemoto Yasuhiko, Takagi Masahiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会

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カテーテルアブレーション施行8ヵ月後検出された右房内血栓の一例 Domestic conference

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 阿保浩二, 藤岡一也, 桑江優子, 大澤政彦, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会

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駆出率が低下した慢性心不全患者における夜間高血圧はbrain natriuretic peptide値と関連する(Higher Nocturnal Blood Pressure is Associated with Brain Natriuretic Peptide Levels in Chronic Heart Failure Patients with Reduced Ejection Fraction) Domestic conference

Kitada Ryoko, Iwata Shinichi, Hanatani Akihisa, Norioka Naoki, Kaga Suwako, Ito Asahiro, Sugioka Kenichi, Takagi Masahiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会

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非弁膜症性心房細動患者における無症候性脳梗塞とCHADS2スコアおよび経食道心エコー所見との関連性(Relation of Silent Brain Infarction to CHADS2 Score and Transesophageal Echocardiographic Findings in Patients with Nonvalvular Atrial Fibrillation) Domestic conference

Kawai Yu, Sugioka Kenichi, Iwata Shinichi, Ishikawa Sera, Norioka Naoki, Fujita Suwako, Ito Asahiro, Hanatani Akihisa, Tatsumi Hiroaki, Doi Atsushi, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会

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Presentation type：Oral presentation (general)
カテーテルアブレーション施行8ヵ月後検出された右房内血栓の一例

伊藤朝広, 杉岡憲一, 岩田真一, 藤田澄吾子, 則岡直樹, 阿保浩二, 藤岡一也, 桑江優子, 大澤政彦, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会
心不全発症を契機にミトコンドリア心筋症の診断に至った左室肥大の一例

市川佳誉, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 安保浩二, 藤岡一也, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会
心エコーにて限局性の心筋炎が疑われた持続性心室頻拍の一例

寺下和範, 杉岡憲一, 岩田真一, 河相優, 藤田澄吾子, 伊藤朝広, 安保浩二, 藤岡一也, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会
完全房室ブロックをきたした心臓原発悪性リンパ腫の一例

武坂絢, 杉岡憲一, 岩田真一, 伊藤朝広, 藤田澄吾子, 阿保浩二, 藤岡一也, 葭山稔

超音波医学 2016.03 (公社)日本超音波医学会
夜間血圧の大きな変動は、駆出率が保持された心房細動患者における左室肥大と関係している(Greater Nighttime Blood Pressure Variability is Associated with Left Atrial Enlargement in Atrial Fibrillation Patients with Preserved Ejection Fraction)

Norioka Naoki, Iwata Shinichi, Sugioka Kenichi, Kaga Suwako, Ito Asahiro, Hanatani Akihisa, Takemoto Yasuhiko, Takagi Masahiko, Yoshiyama Minoru

Circulation Journal 2016.03 (一社)日本循環器学会
重症大動脈弁狭窄症患者における大動脈弓部の動脈硬化は日間血圧変動の増加により論ずることができるか? Domestic conference

岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, Di Tullio MR, 本間俊一, 葭山稔

大阪市医学会雑誌 2015.12 大阪市医学会

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重症大動脈弁狭窄症患者における大動脈弓部の動脈硬化は日間血圧変動の増加により論ずることができるか?

岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, Di Tullio MR, 本間俊一, 葭山稔

大阪市医学会雑誌 2015.12 大阪市医学会
緊急非心臓手術術前に発覚した高度大動脈弁狭窄症に対して順行性大動脈弁バルーン形成術を施行した一例 Domestic conference

寺下和範, 水谷一輝, 松岡雄治郎, 仲川将志, 藤田澄吾子, 坂本祥吾, 伊藤朝広, 岩田真一, 杉岡憲一, 高木雅彦, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会

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透析困難症および重症心不全を伴う大動脈弁狭窄症に対して血行動態改善目的に逆行性大動脈弁バルーン形成術を施行した1例 Domestic conference

市川佳誉, 水谷一輝, 松岡雄治郎, 藤田澄吾子, 伊藤朝広, 岩田真一, 仲川将司, 杉岡憲一, 江原省一, 高木雅彦, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会

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非弁膜症性心房細動における無症候性脳梗塞発症のメカニズム　経食道心エコーによる検討

杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会
非弁膜症性心房細動における無症候性脳梗塞のCHADS2スコアに与える影響

河相優, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会
重症大動脈弁狭窄症における僧帽弁輪石灰化の臨床的意義についての検討

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会
重症大動脈弁狭窄症において、日間血圧変動の増大は大動脈弓部complexプラークの独立した関連因子である

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会
連合弁膜症例に対して、経食道心エコーガイド下で大動脈弁バルーン形成術および僧帽弁交連切開術を同時施行した一例

松岡雄治郎, 水谷一輝, 仲川将志, 藤田澄吾子, 伊藤朝広, 坂本祥吾, 岩田真一, 杉岡憲一, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会
透析困難症および重症心不全を伴う大動脈弁狭窄症に対して血行動態改善目的に逆行性大動脈弁バルーン形成術を施行した1例

市川佳誉, 水谷一輝, 松岡雄治郎, 藤田澄吾子, 伊藤朝広, 岩田真一, 仲川将司, 杉岡憲一, 江原省一, 高木雅彦, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会
緊急非心臓手術術前に発覚した高度大動脈弁狭窄症に対して順行性大動脈弁バルーン形成術を施行した一例

寺下和範, 水谷一輝, 松岡雄治郎, 仲川将志, 藤田澄吾子, 坂本祥吾, 伊藤朝広, 岩田真一, 杉岡憲一, 高木雅彦, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会
非弁膜症性心房細動における無症候性脳梗塞発症のメカニズム　経食道心エコーによる検討 Domestic conference

杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会

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非弁膜症性心房細動における無症候性脳梗塞のCHADS2スコアに与える影響 Domestic conference

河相優, 杉岡憲一, 岩田真一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会

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重症大動脈弁狭窄症における僧帽弁輪石灰化の臨床的意義についての検討 Domestic conference

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会

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重症大動脈弁狭窄症において、日間血圧変動の増大は大動脈弓部complexプラークの独立した関連因子である Domestic conference

則岡直樹, 岩田真一, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 松村嘉起, 花谷彰久, 高木雅彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会

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連合弁膜症例に対して、経食道心エコーガイド下で大動脈弁バルーン形成術および僧帽弁交連切開術を同時施行した一例 Domestic conference

松岡雄治郎, 水谷一輝, 仲川将志, 藤田澄吾子, 伊藤朝広, 坂本祥吾, 岩田真一, 杉岡憲一, 柴田利彦, 葭山稔

日本心臓病学会学術集会抄録 2015.09 (一社)日本心臓病学会

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左房内血栓を合併した連合弁膜症例に対して、血栓溶解療法後に大動脈弁バルーン形成術及び経皮的僧帽弁交連切開術を施行した1例(Successful Antegrade BAV and PTMC for Combined Valvular Heart Disease for the Patient of High-Risk Surgical Operation) Domestic conference

Mizutani Kazuki, Matsuoka Yujiro, Sakaguchi Mikumo, Matsumoto Kenji, Ito Asahiro, Sakamoto Shogo, Nishimura Satoshi, Ishii Hideshi, Nakagawa Masashi, Iwata Shinichi, Matsumura Yoshiki, Hasegawa Takao, Sugioka Kenichi, Ehara Shoichi, Takagi Masahiko, Shimada Kenei, Shibata Toshihiko, Yoshiyama Minoru

日本心血管インターベンション治療学会抄録集 2015.07 (一社)日本心血管インターベンション治療学会

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左房内血栓を合併した連合弁膜症例に対して、血栓溶解療法後に大動脈弁バルーン形成術及び経皮的僧帽弁交連切開術を施行した1例(Successful Antegrade BAV and PTMC for Combined Valvular Heart Disease for the Patient of High-Risk Surgical Operation)

Mizutani Kazuki, Matsuoka Yujiro, Sakaguchi Mikumo, Matsumoto Kenji, Ito Asahiro, Sakamoto Shogo, Nishimura Satoshi, Ishii Hideshi, Nakagawa Masashi, Iwata Shinichi, Matsumura Yoshiki, Hasegawa Takao, Sugioka Kenichi, Ehara Shoichi, Takagi Masahiko, Shimada Kenei, Shibata Toshihiko, Yoshiyama Minoru

日本心血管インターベンション治療学会抄録集 2015.07 (一社)日本心血管インターベンション治療学会
ムコ多糖症に合併した大動脈弁・僧帽弁狭窄の心エコー図によるフォロー Domestic conference

穂積健之, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 杉岡憲一, 田中あけみ, 葭山稔

超音波医学 2015.04 (公社)日本超音波医学会

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大動脈弁狭窄症患者における僧帽弁輪石灰化とエコーによる指標との関連 Domestic conference

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 葭山稔

超音波医学 2015.04 (公社)日本超音波医学会

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ムコ多糖症に合併した大動脈弁・僧帽弁狭窄の心エコー図によるフォロー

穂積健之, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 杉岡憲一, 田中あけみ, 葭山稔

超音波医学 2015.04 (公社)日本超音波医学会
大動脈弁狭窄症患者における僧帽弁輪石灰化とエコーによる指標との関連

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 葭山稔

超音波医学 2015.04 (公社)日本超音波医学会
非弁膜症性心房細動患者における無症候性脳梗塞と大動脈弓アテローム性動脈硬化症　経食道心エコーによる検討(Silent Brain Infarcts and Aortic Arch Atherosclerosis in Patients with Nonvalvular Atrial Fibrillation: A Transesophageal Echocardiographic Study) Domestic conference

Sugioka Kenichi, Fujita Suwako, Ito Asahiro, Iwata Shinichi, Matsumura Yoshiki, Hanatani Akihisa, Doi Atsushi, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2015.03 (一社)日本循環器学会

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非弁膜症性心房細動患者における無症候性脳梗塞と大動脈弓アテローム性動脈硬化症　経食道心エコーによる検討(Silent Brain Infarcts and Aortic Arch Atherosclerosis in Patients with Nonvalvular Atrial Fibrillation: A Transesophageal Echocardiographic Study)

Sugioka Kenichi, Fujita Suwako, Ito Asahiro, Iwata Shinichi, Matsumura Yoshiki, Hanatani Akihisa, Doi Atsushi, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2015.03 (一社)日本循環器学会
大動脈狭窄患者における僧帽弁輪石灰化と心エコーパラメーターの関連(Relationship between Mitral Annular Calcification and Echocardiographic Parameters in Patients with Aortic Stenosis) Domestic conference

Fujita Suwako, Sugioka Kenichi, Iwata Shinichi, Ito Asahiro, Matsumura Yoshiki, Hanatani Akihisa, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2015.03 (一社)日本循環器学会

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大動脈狭窄患者における僧帽弁輪石灰化と心エコーパラメーターの関連(Relationship between Mitral Annular Calcification and Echocardiographic Parameters in Patients with Aortic Stenosis)

Fujita Suwako, Sugioka Kenichi, Iwata Shinichi, Ito Asahiro, Matsumura Yoshiki, Hanatani Akihisa, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2015.03 (一社)日本循環器学会
非弁膜症性心房細動における大動脈プラークと心不全との関連　経食道心エコー図による検討 Domestic conference

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 花谷彰久, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2014.09 (一社)日本心臓病学会

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非弁膜症性心房細動例におけるCHADS2スコアと大動脈complexプラークとの関連

杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 花谷彰久, 仲川将志, 高木雅彦, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2014.09 (一社)日本心臓病学会
非弁膜症性心房細動における大動脈プラークと心不全との関連　経食道心エコー図による検討

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 花谷彰久, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2014.09 (一社)日本心臓病学会
非弁膜症性心房細動例におけるCHADS2スコアと大動脈complexプラークとの関連 Domestic conference

杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 花谷彰久, 仲川将志, 高木雅彦, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会学術集会抄録 2014.09 (一社)日本心臓病学会

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胸部X線造影における大動脈弓石灰化は非弁膜症心房細動患者における大動脈弓部の複雑なプラークの簡易的な予測因子である(Aortic Arch Calcification on chest X-ray is a simple predictor of Aortic Arch Complex Plaques in patients with Nonvalvular Atrial Fibrillation) Domestic conference

Ito Asahiro, Sugioka Kenichi, Fujita Suwako, Iwata Shinichi, Matsumura Yoshiki, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

日本動脈硬化学会総会プログラム・抄録集 2014.06 (一社)日本動脈硬化学会

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胸部X線造影における大動脈弓石灰化は非弁膜症心房細動患者における大動脈弓部の複雑なプラークの簡易的な予測因子である(Aortic Arch Calcification on chest X-ray is a simple predictor of Aortic Arch Complex Plaques in patients with Nonvalvular Atrial Fibrillation)

Ito Asahiro, Sugioka Kenichi, Fujita Suwako, Iwata Shinichi, Matsumura Yoshiki, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

日本動脈硬化学会総会プログラム・抄録集 2014.06 (一社)日本動脈硬化学会
左室収縮機能低下患者における左室拡張機能障害は右室機能障害と関連がある(Left Ventricular Diastolic Dysfunction is Associated with Right Ventricular Dysfunction in Patients with Decreased Left Ventricular Systolic Function) Domestic conference

Yamashita Tomoko, Matsumura Yoshiki, Sugioka Kenichi, Iwata Shinichi, Ito Asahiro, Fujita Suwako, Hanatani Akihisa, Yoshiyama Minoru

Circulation Journal 2014.03 (一社)日本循環器学会

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心エコー検査結果の駆出率およびE/e'に基づく分類が心筋梗塞の長期予後に及ぼす影響(Impact of Echocardiographic Classification Based on Ejection Fraction and E/e' on Long-term Prognosis of Myocardial Infarction) Domestic conference

Matsusaki Nanao, Okura Hiroyuki, Kanai Miwa, Fujimoto Tadao, Sakamoto Yuya, Hayashi Yusuke, Ito Asahiro, Tamura Kenji, Kuge Nobuya, Murata Eriko, Yoshida Kiyoshi, Yoshiyama Minoru, Kataoka Toru

Circulation Journal 2014.03 (一社)日本循環器学会

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左室収縮機能低下患者における左室拡張機能障害は右室機能障害と関連がある(Left Ventricular Diastolic Dysfunction is Associated with Right Ventricular Dysfunction in Patients with Decreased Left Ventricular Systolic Function)

Yamashita Tomoko, Matsumura Yoshiki, Sugioka Kenichi, Iwata Shinichi, Ito Asahiro, Fujita Suwako, Hanatani Akihisa, Yoshiyama Minoru

Circulation Journal 2014.03 (一社)日本循環器学会
心エコー検査結果の駆出率およびE/e'に基づく分類が心筋梗塞の長期予後に及ぼす影響(Impact of Echocardiographic Classification Based on Ejection Fraction and E/e' on Long-term Prognosis of Myocardial Infarction)

Matsusaki Nanao, Okura Hiroyuki, Kanai Miwa, Fujimoto Tadao, Sakamoto Yuya, Hayashi Yusuke, Ito Asahiro, Tamura Kenji, Kuge Nobuya, Murata Eriko, Yoshida Kiyoshi, Yoshiyama Minoru, Kataoka Toru

Circulation Journal 2014.03 (一社)日本循環器学会
重症大動脈弁狭窄症における日間血圧変動と大動脈弓部プラークとの関連 Domestic conference

岩田真一, 杉岡憲一, 松村嘉起, 藤田澄吾子, 伊藤朝広, 穂積健之, 北田諒子, 花谷彰久, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会

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非弁膜症性心房細動例における大動脈プラークの頻度と関連因子について　経食道心エコーによる検討

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 穂積健之, 花谷彰久, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会
非弁膜症性心房細動における経食道心エコーによる大動脈プラーク検索の意義　CHA2DS2-VAScスコアへの影響

山下智子, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会
重症大動脈弁狭窄症における日間血圧変動と大動脈弓部プラークとの関連

岩田真一, 杉岡憲一, 松村嘉起, 藤田澄吾子, 伊藤朝広, 穂積健之, 北田諒子, 花谷彰久, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会
頸動脈エコーにより大動脈プラークは予測可能か?　頸動脈エコーと経食道心エコーとの比較検討 Domestic conference

伊藤朝広, 杉岡憲一, 岩田真一, 松村嘉起, 藤田澄吾子, 花谷彰久, 穂積健之, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会

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非弁膜症性心房細動例における大動脈プラークの頻度と関連因子について　経食道心エコーによる検討 Domestic conference

藤田澄吾子, 杉岡憲一, 岩田真一, 伊藤朝広, 松村嘉起, 穂積健之, 花谷彰久, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会

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非弁膜症性心房細動における経食道心エコーによる大動脈プラーク検索の意義　CHA2DS2-VAScスコアへの影響 Domestic conference

山下智子, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 土井淳史, 高木雅彦, 上田真喜子, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会

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頸動脈エコーにより大動脈プラークは予測可能か?　頸動脈エコーと経食道心エコーとの比較検討

伊藤朝広, 杉岡憲一, 岩田真一, 松村嘉起, 藤田澄吾子, 花谷彰久, 穂積健之, 葭山稔

日本心臓病学会誌 2013.09 (一社)日本心臓病学会
日々の血圧変動と大動脈弓部アテローム硬化の関連性(Relationship Between Day-by-day Blood Pressure Variability and Aortic Arch Atherosclerosis) Domestic conference

Iwata Shinichi, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Ito Asahiro, Hozumi Takeshi, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

日本動脈硬化学会総会プログラム・抄録集 2013.06 (一社)日本動脈硬化学会

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日々の血圧変動と大動脈弓部アテローム硬化の関連性(Relationship Between Day-by-day Blood Pressure Variability and Aortic Arch Atherosclerosis)

Iwata Shinichi, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Ito Asahiro, Hozumi Takeshi, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

日本動脈硬化学会総会プログラム・抄録集 2013.06 (一社)日本動脈硬化学会
血圧日間変動と大動脈弓アテローム性動脈硬化症の関連性(Relationship Between Day-by-day Blood Pressure Variability and Aortic Arch Atherosclerosis) Domestic conference

Iwata Shinichi, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Ito Asahiro, Hozumi Takeshi, Hanatani Akihisa, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会

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非弁膜症性心房細動患者における大動脈プラークの有病率　経食道心エコー研究(The Prevalence of Aortic Plaques in Patients with Nonvalvular Atrial Fibrillation: A Transesophageal Echocardiographic Study)

Fujita Suwako, Sugioka Kenichi, Ito Asahiro, Matsumura Yoshiki, Iwata Shinichi, Takagi Masahiko, Hozumi Takeshi, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会
重度大動脈弁狭窄に対する大動脈弁置換後の肺高血圧に左房容積が及ぼす影響(Impact of Left Atrial Volume on Pulmonary Hypertension after Aortic Valve Replacement for Severe Aortic Stenosis)

Matsumura Yoshiki, Sugioka Kenichi, Iwata Shinichi, Yamashita Tomoko, Fujita Suwako, Ito Asahiro, Hozumi Takeshi, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会
血圧日間変動と大動脈弓アテローム性動脈硬化症の関連性(Relationship Between Day-by-day Blood Pressure Variability and Aortic Arch Atherosclerosis)

Iwata Shinichi, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Ito Asahiro, Hozumi Takeshi, Hanatani Akihisa, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会
大動脈弁狭窄患者における近位胸部大動脈の形態学的変化　二尖弁患者と三尖弁患者の比較(Morphological Changes in the Proximal Thoracic Aorta in Patients with Aortic Stenosis: Comparison between Patients with Bicuspid and Tricuspid Valve) Domestic conference

Fujita Suwako, Sugioka Kenichi, Matsumura Yoshiki, Ito Asahiro, Iwata Shinichi, Hozumi Takeshi, Ueda Makiko, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会

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非弁膜症性心房細動患者における大動脈プラークの有病率　経食道心エコー研究(The Prevalence of Aortic Plaques in Patients with Nonvalvular Atrial Fibrillation: A Transesophageal Echocardiographic Study) Domestic conference

Fujita Suwako, Sugioka Kenichi, Ito Asahiro, Matsumura Yoshiki, Iwata Shinichi, Takagi Masahiko, Hozumi Takeshi, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会

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重度大動脈弁狭窄に対する大動脈弁置換後の肺高血圧に左房容積が及ぼす影響(Impact of Left Atrial Volume on Pulmonary Hypertension after Aortic Valve Replacement for Severe Aortic Stenosis) Domestic conference

Matsumura Yoshiki, Sugioka Kenichi, Iwata Shinichi, Yamashita Tomoko, Fujita Suwako, Ito Asahiro, Hozumi Takeshi, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会

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大動脈弁狭窄患者における近位胸部大動脈の形態学的変化　二尖弁患者と三尖弁患者の比較(Morphological Changes in the Proximal Thoracic Aorta in Patients with Aortic Stenosis: Comparison between Patients with Bicuspid and Tricuspid Valve)

Fujita Suwako, Sugioka Kenichi, Matsumura Yoshiki, Ito Asahiro, Iwata Shinichi, Hozumi Takeshi, Ueda Makiko, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2013.03 (一社)日本循環器学会
慢性腎臓病と大動脈プラークとの関連　近位胸部大動脈と遠位胸部大動脈との比較検討 Domestic conference

松村嘉起, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 2012.08 (一社)日本心臓病学会

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大動脈弁狭窄症における冠動脈疾患合併と大動脈弓部プラークとの関連　経食道心エコー図による検討 Domestic conference

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 2012.08 (一社)日本心臓病学会

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大動脈弁狭窄症における近位胸部大動脈の形態的変化についての検討　三尖弁と二尖弁大動脈弁狭窄症の比較 Domestic conference

藤田澄吾子, 杉岡憲一, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 2012.08 (一社)日本心臓病学会

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大動脈弁狭窄症における冠動脈疾患合併と大動脈弓部プラークとの関連　経食道心エコー図による検討

伊藤朝広, 杉岡憲一, 藤田澄吾子, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 2012.08 (一社)日本心臓病学会
慢性腎臓病と大動脈プラークとの関連　近位胸部大動脈と遠位胸部大動脈との比較検討

松村嘉起, 杉岡憲一, 藤田澄吾子, 伊藤朝広, 岩田真一, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 2012.08 (一社)日本心臓病学会
大動脈弁狭窄症における近位胸部大動脈の形態的変化についての検討　三尖弁と二尖弁大動脈弁狭窄症の比較

藤田澄吾子, 杉岡憲一, 伊藤朝広, 岩田真一, 松村嘉起, 穂積健之, 末廣茂文, 葭山稔

日本心臓病学会誌 2012.08 (一社)日本心臓病学会
弁膜症の診断と治療　重症大動脈弁狭窄症における経食道心エコーによる大動脈弓部プラークの評価について Domestic conference

杉岡憲一, 穂積健之, 松村嘉起, 伊藤朝広, 葭山稔

超音波医学 2012.04 (公社)日本超音波医学会

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弁膜症の診断と治療　重症大動脈弁狭窄症における経食道心エコーによる大動脈弓部プラークの評価について

杉岡憲一, 穂積健之, 松村嘉起, 伊藤朝広, 葭山稔

超音波医学 2012.04 (公社)日本超音波医学会
重症心臓弁膜症患者における大動脈弓プラークの有病率と相関性　経食道心エコー研究(Prevalence and Correlates of Aortic Arch Plaques in Patients with Significant Valvular Heart Disease: A Transesophageal Echocardiographic Study) Domestic conference

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Hozumi Takeshi, Fujita Suwako, Nakata Shinji, Mizutani Kazuki, Naruko Takahiko, Ueda Makiko, Hosono Mitsuharu, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2012.03 (一社)日本循環器学会

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重症心臓弁膜症患者における大動脈弓プラークの有病率と相関性　経食道心エコー研究(Prevalence and Correlates of Aortic Arch Plaques in Patients with Significant Valvular Heart Disease: A Transesophageal Echocardiographic Study)

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Hozumi Takeshi, Fujita Suwako, Nakata Shinji, Mizutani Kazuki, Naruko Takahiko, Ueda Makiko, Hosono Mitsuharu, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2012.03 (一社)日本循環器学会
大動脈弓アテローム性動脈硬化症評価におけるリアルタイム三次元経食道心エコー検査の有用性(Utility of Real-time 3 Dimensional Transesophageal Echocardiography for the Assessment of Aortic Arch Atherosclerosis) Domestic conference

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Yoshiyama Tomotaka, Takagi Masahiko, Hozumi Takeshi, Yoshiyama Minoru

Circulation Journal 2012.03 (一社)日本循環器学会

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Presentation type：Oral presentation (general)
大動脈弓アテローム性動脈硬化症評価におけるリアルタイム三次元経食道心エコー検査の有用性(Utility of Real-time 3 Dimensional Transesophageal Echocardiography for the Assessment of Aortic Arch Atherosclerosis)

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Yoshiyama Tomotaka, Takagi Masahiko, Hozumi Takeshi, Yoshiyama Minoru

Circulation Journal 2012.03 (一社)日本循環器学会
組織ドップラー法と二次元スペックルトラッキング法による左室壁運動評価の比較 Domestic conference

森下陽子, 大倉宏之, 坂口海雲, 伊藤朝広, 片岡亨, 松下未来, 田村小枝, 山辺梓, 中村恵, 高田裕子, 清水啓子

日本心臓病学会誌 2011.08 (一社)日本心臓病学会

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慢性腎臓病は大動脈弓プラークの関連因子である　経食道心エコー図を用いた検討 Domestic conference

松村嘉起, 杉岡憲一, 穂積健之, 藤田澄吾子, 伊藤朝広, 高木雅彦, 水谷一輝, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会

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リアルタイム3次元経食道心エコー図による大動脈弓プラークの評価についての検討 Domestic conference

伊藤朝広, 杉岡憲一, 松村嘉起, 藤田澄吾子, 高木雅彦, 穂積健之, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会

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Presentation type：Oral presentation (general)
組織ドップラー法と二次元スペックルトラッキング法による左室壁運動評価の比較

森下陽子, 大倉宏之, 坂口海雲, 伊藤朝広, 片岡亨, 松下未来, 田村小枝, 山辺梓, 中村恵, 高田裕子, 清水啓子

日本心臓病学会誌 2011.08 (一社)日本心臓病学会
大動脈弁狭窄症における大動脈弓complexプラークと脳梗塞発症との関連　経食道心エコー図による検討 Domestic conference

吉山智貴, 杉岡憲一, 穂積健之, 松村嘉起, 藤田澄吾子, 伊藤朝広, 水谷一輝, 成子隆彦, 上田真喜子, 末廣茂文, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会

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大動脈弁狭窄と大動脈弓プラークとの関連　経食道心エコー図による検討 Domestic conference

藤田澄吾子, 杉岡憲一, 穂積健之, 伊藤朝広, 松村嘉起, 成子隆彦, 上田真喜子, 河瀬吉雄, 西本正紀, 末廣茂文, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会

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Presentation type：Oral presentation (general)
リアルタイム3次元経食道心エコー図による大動脈弓プラークの評価についての検討

伊藤朝広, 杉岡憲一, 松村嘉起, 藤田澄吾子, 高木雅彦, 穂積健之, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会
慢性腎臓病は大動脈弓プラークの関連因子である　経食道心エコー図を用いた検討

松村嘉起, 杉岡憲一, 穂積健之, 藤田澄吾子, 伊藤朝広, 高木雅彦, 水谷一輝, 成子隆彦, 上田真喜子, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会
大動脈弁狭窄症における大動脈弓complexプラークと脳梗塞発症との関連　経食道心エコー図による検討

吉山智貴, 杉岡憲一, 穂積健之, 松村嘉起, 藤田澄吾子, 伊藤朝広, 水谷一輝, 成子隆彦, 上田真喜子, 末廣茂文, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会
大動脈弁狭窄と大動脈弓プラークとの関連　経食道心エコー図による検討

藤田澄吾子, 杉岡憲一, 穂積健之, 伊藤朝広, 松村嘉起, 成子隆彦, 上田真喜子, 河瀬吉雄, 西本正紀, 末廣茂文, 葭山稔

日本心臓病学会誌 2011.08 (一社)日本心臓病学会
大動脈弁狭窄患者における複雑な形態を有する大動脈弓プラークと脳梗塞リスク(Aortic Arch Plaques with Complex Morphology and Risk of Cerebral Infarction in Patients with Aortic Valve Stenosis) Domestic conference

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Ohtsuka Ryo, Hozumi Takeshi, Naruko Takahiko, Ueda Makiko, Hosono Koji, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2011.03 (一社)日本循環器学会

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大動脈弁狭窄症患者における形態が複雑な大動脈プラークの高有病率　経食道心エコー研究(Higher Prevalence of Aortic Plaques with Complex Morphology in Patients with Aortic Valve Stenosis: A Transesophageal Echocardiographic Study) Domestic conference

Fujita Suwako, Sugioka Kenichi, Matsumura Yoshiki, Ito Asahiro, Otsuka Ryo, Hozumi Takeshi, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2011.03 (一社)日本循環器学会

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Presentation type：Oral presentation (general)
大動脈弁狭窄患者における複雑な形態を有する大動脈弓プラークと脳梗塞リスク(Aortic Arch Plaques with Complex Morphology and Risk of Cerebral Infarction in Patients with Aortic Valve Stenosis)

Ito Asahiro, Sugioka Kenichi, Matsumura Yoshiki, Fujita Suwako, Ohtsuka Ryo, Hozumi Takeshi, Naruko Takahiko, Ueda Makiko, Hosono Koji, Suehiro Shigefumi, Yoshiyama Minoru

Circulation Journal 2011.03 (一社)日本循環器学会
大動脈弁狭窄症患者における形態が複雑な大動脈プラークの高有病率　経食道心エコー研究(Higher Prevalence of Aortic Plaques with Complex Morphology in Patients with Aortic Valve Stenosis: A Transesophageal Echocardiographic Study)

Fujita Suwako, Sugioka Kenichi, Matsumura Yoshiki, Ito Asahiro, Otsuka Ryo, Hozumi Takeshi, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru

Circulation Journal 2011.03 (一社)日本循環器学会

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