Updated on 2024/10/01

写真a

 
TERAI Hidetomi
 
Organization
Graduate School of Medicine Department of Clinical Medical Science Professor
School of Medicine Department of Medical Science
Title
Professor
Affiliation
Institute of Medicine
Affiliation campus
Abeno Campus

Position

  • Graduate School of Medicine Department of Clinical Medical Science 

    Professor  2024.10 - Now

  • Graduate School of Medicine Department of Clinical Medical Science 

    Associate Professor  2015.04 - 2024.09

  • School of Medicine Department of Medical Science 

    Professor  2024.10 - Now

  • School of Medicine Department of Medical Science 

    Associate Professor  2022.04 - 2024.09

Degree

  • 医学博士 ( Osaka City University )

Research Areas

  • Life Science / Orthopedics  / Spine surgery

Research Interests

  • 脊椎外科 整形外科 骨再生

Research subject summary

  • 脊椎外科学、低侵襲脊椎手術、小児脊椎脊髄病に関する研究

Research Career

  • spinal surgery, endoscopic surgery

    Spine, Endoscopy 

    2002.04 - Now 

  • 脊椎外科学に関する研究 骨組織再生に関する研究

    脊椎外科 骨再生  Individual

    1998.04 - Now 

Professional Memberships

  • Japanese Orthopaedic Association

    1997.08 - Now   Domestic

  • The International Society for the Study of the Lumbar Spine; ISSLS

    2022.10 - Now   Overseas

  • ムコ多糖症研究会

    2018.08 - Now

  • North American Spine Society (NASS)

    2015.07 - Now   Overseas

  • 日本脊椎インスツルメンテーション学会

    2010.04 - Now

  • 日本腰痛学会

    2009.11 - Now

  • 日本側弯症学会

    2008.10 - Now   Domestic

  • Pacific and Asian Society of Minimally Invasive Spine Surgery; PASMISS

    2005.04 - Now   Overseas

  • 日本低侵襲脊椎外科学会

    2005.04 - Now

  • Japanese Society for Spine Surgery and Related Research

    2003.03 - Now   Domestic

  • 日本骨代謝学会

    2002.08 - 2017.06   Domestic

▼display all

Awards

  • Best presentation award in 26th JPSTSS

    Hidetomi Terai

    2019.09   Japan Society for the Study of Surgical Technique for Spine and Spinal Nerves (JPSTSS)   Minimum Invasive PLIF using CBT/TASS technique for Isthmic Spondylolisthesis

  • ISSLS Prize- clinical science

    International Society for the Study of the Lumbar Spine

    2019.06   ISSLS PRIZE IN CLINICAL SCIENCE 2019: clinical importance of trunk muscle mass for low back pain, spinal balance, and quality of life-a multicenter cross-sectional study.

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    Country:Sweden

    Trunk muscle mass was significantly associated with the ODI, VAS score, SVA, and EQ5D score. Trunk muscle mass may assume an important role to elucidate and treat lumbar spinal dysfunction and spinal imbalance. These slides can be retrieved under Electronic Supplementary Material.

  • 若手研究者表彰事業・奨励賞

    2009.11   長寿科学振興財団  

Job Career (off-campus)

  • Masachussetts General Hospital, Harvard Medical School   Tissue Engineering Lab, Dept. of Surgery   Research fellow

    1999.12 - 2001.11

  • 近畿大学医学部    麻酔科   麻酔科 研修医

    1995.05 - 1997.04

Education

  • Osaka City University   Orthopedic surgery   Doctor's Course   Graduated/Completed

    1998.04 - 2002.03

  • Tohoku University     Graduated/Completed

    1989.04 - 1995.03

Papers

  • Residual Paresthesia after Surgery for Degenerative Cervical Myelopathy: Incidence and Impact on Clinical Outcomes and Satisfaction. Reviewed

    Tamai K, Terai H, Iwamae M, Kato M, Toyoda H, Suzuki A, Takahashi S, Sawada Y, Okamura Y, Kobayashi Y, Nakamura H

    Spine   2023.12( ISSN:0362-2436

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/BRS.0000000000004907

    PubMed

  • 【脊椎脊髄疾患に対するリハビリテーション~Now and the Future~】腰曲がりに対するリハビリテーション Reviewed

    寺井 秀富, 高橋 真治, 谷脇 浩志, 星野 雅俊

    Journal of Clinical Rehabilitation   32 ( 13 )   1277 - 1281   2023.11( ISSN:0918-5259

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    Publishing type:Research paper (scientific journal)  

  • The Impact of Multidisciplinary Approaches to Social Functioning on Surgical Outcomes After Surgery for Cervical Myelopathy. Reviewed

    Tamai K, Terai H, Watanabe S, Tashiro Y, Omine T, Katsuda H, Shimada N, Kobayashi Y, Nakamura H

    Spine   48 ( 19 )   1365 - 1372   2023.10( ISSN:0362-2436

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/BRS.0000000000004764

    PubMed

  • 【リハビリテーション診療update】(IV章)リハビリテーションが必要となる疾患 運動器疾患 脊椎疾患 Reviewed

    寺井 秀富, 中村 博亮, 池淵 充彦

    日本医師会雑誌   152 ( 特別2 )   S160 - S161   2023.10( ISSN:0021-4493

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    Publishing type:Research paper (scientific journal)  

  • Prognostic impact of respiratory dysfunction in elderly patients with cervical spinal cord injury and/or fractures: a multicenter survey. Reviewed

    Hirota R, Terashima Y, Ohnishi H, Yamashita T, Yokogawa N, Sasagawa T, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   32 ( 10 )   3522 - 3532   2023.10( ISSN:0940-6719

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00586-023-07828-9

    PubMed

  • 特集 整形外科領域における人工知能(AI) 人工知能技術を活用した椎体骨折の画像診断 Reviewed

    藪 晋人, 高橋 真治, 星野 雅俊, 寺井 秀富

    整形・災害外科   66 ( 10 )   1169 - 1174   2023.09( ISSN:03874095

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.18888/se.0000002701

  • 【整形外科領域における人工知能(AI)】人工知能技術を活用した椎体骨折の画像診断 Reviewed

    藪 晋人, 高橋 真治, 星野 雅俊, 寺井 秀富

    整形・災害外科   66 ( 10 )   1169 - 1174   2023.09( ISSN:0387-4095

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    Publishing type:Research paper (scientific journal)  

    <文献概要>椎体骨折において,適切な診断や治療介入の遅れは患者の著しい生活の質の低下を引き起こし,問題となる。よって診断の質の確保は喫緊の課題であり,その中で画像診断は重要な役割を担う。高齢者では陳旧性椎体骨折を有することが多く,新鮮骨粗鬆症性椎体骨折(OVF)の診断に加え,脊椎腫瘍や感染性脊椎炎などによる病的骨折との鑑別も必要となるため,画像診断に難渋することが多い。近年,人工知能(AI)を活用した椎体骨折画像診断システムの報告が増加しており,診断精度の向上にかかる期待は大きい。われわれが構築したMRIにおける新鮮・陳旧性OVFのAI識別システム1)の識別能は良好であり,脊椎外科医と同等であった。AIを活用した椎体骨折画像診断システム開発の今後のさらなる発展が望まれる。

  • Risk of Revision After Vertebral Augmentation for Osteoporotic Vertebral Fracture: A Narrative Review. Reviewed

    Takahashi S, Inose H, Tamai K, Iwamae M, Terai H, Nakamura H

    Neurospine   20 ( 3 )   852 - 862   2023.09( ISSN:2586-6583

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.14245/ns.2346560.280

    PubMed

  • Management of Antithrombotic Drugs before Elective Spine Surgery: A Nationwide Web-Based Questionnaire Survey in Japan(タイトル和訳中) Reviewed

    Tezuka Fumitake, Sakai Toshinori, Imagama Shiro, Takahashi Hiroshi, Takaso Masashi, Aizawa Toshimi, Otani Koji, Okuda Shinya, Kato Satoshi, Kanemura Tokumi, Kawaguchi Yoshiharu, Konishi Hiroaki, Suda Kota, Terai Hidetomi, Nakanishi Kazuo, Nishida Kotaro, Machino Masaaki, Miyakoshi Naohisa, Murakami Hideki, Yamato Yu, Yukawa Yasutsugu, Medical Safety Promotion Committee of The Japanese Society for Spine Surgery and Related Research

    Spine Surgery and Related Research   7 ( 5 )   428 - 435   2023.09

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    Publishing type:Research paper (scientific journal)  

  • 【成人脊柱変形とロコモ】骨粗鬆症性椎体骨折と体幹筋力・脊椎アライメントの関連 Reviewed

    高橋 真治, 大山 翔一朗, 堀 悠介, 星野 雅俊, 寺井 秀富, 中村 博亮

    Loco Cure   9 ( 3 )   236 - 242   2023.08( ISSN:2189-4221

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    Publishing type:Research paper (scientific journal)  

    脊椎アライメントの異常は腰背部痛や歩行障害,QOL低下などの要因となりうる.脊椎アライメント不良の関連因子として年齢や骨粗鬆症性椎体骨折(osteoporotic vertebral fracture:OVF),体幹筋低下などが報告されている.OVFは脊椎および骨盤のパラメーターを変化させるが,筋力により代償機構がはたらくと脊椎のバランスを保持できる.しかし体幹筋量が減少すると脊椎アライメントや腰痛,QOLに影響を及ぼすことが示されている.さらに,縦断研究では,ロコモ度2が脊椎アライメント悪化の予測因子であり,運動介入が予防に有効である可能性も示唆された.これらの知見は,高齢者の健康寿命維持に重要な情報となりうる.(著者抄録)

  • Prognosis of Cervical Diffuse Idiopathic Skeletal Hyperostosis-Related Spine Injuries in Elderly Patients: Analyses of Both Fracture and Spinal Cord Injury Without Fracture. Reviewed

    Segi N, Nakashima H, Machino M, Ito S, Yokogawa N, Sasagawa T, Funayama T, Eto F, Yamaji A, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Iizuka Y, Takasawa E, Akeda K, Takegami N, Kiyasu K, Tominaga H, Tokumoto H, Funao H, Oshima Y, Yoshii T, Kaito T, Sakai D, Ohba T, Seki S, Otsuki B, Ishihara M, Miyazaki M, Okada S, Imagama S, Kato S

    Global spine journal   21925682231186757   2023.07( ISSN:2192-5682

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/21925682231186757

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  • Development of locomotive syndrome in elderly population after COVID-19 outbreak: A population-based cross-sectional study with over 12,000 participants(タイトル和訳中) Reviewed

    Terai Hidetomi, Tamai Koji, Takahashi Shinji, Katsuda Hiroshi, Shimada Nagakazu, Hori Yusuke, Kobayashi Yuto, Nakamura Hiroaki

    Journal of Orthopaedic Science   28 ( 4 )   895 - 900   2023.07( ISSN:0949-2658

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    Publishing type:Research paper (scientific journal)  

  • Factors Predicting the Final Diagnosis in Image-Guided Percutaneous Needle Biopsy for Suspected Spinal Tumors. Reviewed

    Oka M, Suzuki A, Terai H, Kato M, Toyoda H, Takahashi S, Tamai K, Nakamura H

    Journal of clinical medicine   12 ( 13 )   2023.06( ISSN:2077-0383

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/jcm12134292

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  • Muscle strength rather than appendicular skeletal muscle mass might affect spinal sagittal alignment, low back pain, and health-related quality of life. Reviewed

    Tanaka Y, Miyagi M, Inoue G, Hori Y, Inage K, Murata K, Fujimaki H, Kuroda A, Yokozeki Y, Inoue S, Mimura Y, Takahashi S, Ohyama S, Terai H, Hoshino M, Suzuki A, Tsujio T, Toyoda H, Orita S, Eguchi Y, Shiga Y, Furuya T, Maki S, Ikeda S, Shirasawa E, Imura T, Nakazawa T, Uchida K, Ohtori S, Nakamura H, Takaso M

    Scientific reports   13 ( 1 )   9894   2023.06

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-023-37125-w

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  • Risk of Residual Low Back Pain in Conservative Treatment of Osteoporotic Vertebral Fractures without Poor Prognostic Factors on Magnetic Resonance Imaging Reviewed

    Iwamae Masayoshi, Terai Hidetomi, Tamai Koji, Hoshino Masatoshi, Takahashi Shinji, Umano Masayuki, Kobayashi Yuto, Katsuda Hiroshi, Kaneda Kunikazu, Shimada Nagakazu, Nakamura Hiroaki

    Journal of Spine Research   14 ( 5 )   786 - 793   2023.05( ISSN:18847137 ( eISSN:24351563

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    Publishing type:Research paper (scientific journal)  

    <p><b>Introduction: </b>Poor prognostic factors (PPF) on magnetic resonance imaging (MRI) (confined high intensity area or diffuse low intensity area in fractured vertebrae on T2-weighted MR images) predict delayed union after osteoporotic vertebral fractures (OVF). However, although we have treated OVF without PPF on MRI conservatively, there have been a few cases with residual low back pain. Therefore, the objectives of this study were to identify the risk factors of residual low back pain despite the absence of PPF on MRI, and to investigate clinical and radiographical characteristics during follow-up in such patients.</p><p><b>Methods: </b>This retrospective cohort study included 55 patients (mean age 75.1 years, 47 females) who were followed up for over 6 months after conservative treatment for OVF. The cases with PPF on MRI or with cauda equina or nerve root compressed on MRI were excluded. The participants were divided into two groups: the residual low back pain group (VAS in low back pain ≥40 at 6 months; 16 patients) and the control group (39 patients). Evaluation items included radiographic parameters on dynamic films (sitting/supine lateral views) and whole spine X-ray, VAS in low back pain/buttock pain at the initial examination and 6 months after injury.</p><p><b>Results: </b>Firstly, to identify the risk factors, univariate analysis showed significant differences in VAS in buttock pain at initial examination (p = 0.002), motion angle of fractured vertebrae (p = 0.047), TK (p = 0.046), and LL (p = 0.031). Multivariate analysis showed that VAS in buttock pain at first examination was an independent risk factor for residual low back pain 6 months after injury (adjusted odds ratio = 1.526, p = 0.019). Secondly, the patients in the residual low back pain group were significantly larger SVA at 6 months and more change in the height of anterior wall of fractured vertebrae in dynamic films at 6 months than those in the control group (p = 0.029 and p = 0.011, respectively). Moreover, the cases with confined high intensity area on T2-weighted images at 6 months were significantly more in the residual low back pain group than in the control group (p = 0.006). </p><p><b>Conclusions: </b>The risk factor for residual low back pain after conservative treatment for OVF without PPF on MRI was buttock pain at the initial examination. The causes of residual low back pain were a larger SVA and delayed union of the fractured vertebrae. Patients with buttock pain at the initial examination should be carefully followed up, and surgical intervention such as vertebroplasty might be considered as necessary.</p>

    DOI: 10.34371/jspineres.2022-0050

  • Risk Factors for Poor Outcome after Palliative Surgery for Metastatic Spinal Tumors. Reviewed

    Suzuki A, Terai H, Takahashi S, Kato M, Toyoda H, Tamai K, Hori Y, Okamura Y, Nakamura H

    Journal of clinical medicine   12 ( 10 )   2023.05( ISSN:2077-0383

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/jcm12103442

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  • A case report of pathological fracture of the thoracic spine with a difficulty in diagnosis Reviewed

    SUZUKI Maya

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   66 ( 3 )   507 - 508   2023.05( ISSN:00089443 ( eISSN:13490885

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.11359/chubu.2023.507

  • Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity Reviewed

    Edahiro R.

    Nature Genetics   55 ( 5 )   753 - 767   2023.05( ISSN:10614036

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41588-023-01375-1

  • 高齢のロコモティブシンドローム患者の検出に用いられる人工知能モデル 横断研究(Artificial intelligence model to identify elderly patients with locomotive syndrome: A cross-section study) Reviewed

    Takahashi Shinji, Nonomiya Yuta, Terai Hidetomi, Hoshino Masatoshi, Ohyama Shoichiro, Shintani Ayumi, Nakamura Hiroaki

    Journal of Orthopaedic Science   28 ( 3 )   656 - 661   2023.05( ISSN:0949-2658

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    高齢のロコモティブシンドローム(LS)患者の検出に用いられる人工知能(AI)ベースの決定システムを開発し、その有用性について検討した。高齢者409名(男性164名、女性245名、平均73.5±5.4歳)を対象に、横断研究を実施して足部スキャン圧システムとして歩行中の足底圧分布を測定し、さらに画像処理システムには畳み込みニューラルネットワーク(CNN)を用いて足底圧をベースにLSの発症可能性を推定した。AIモデルのロジスティック回帰段階では、年齢、性別、身長、体重およびCNNの出力にもとづいて発症予測方程式を作成した。開発コホートの対象者は300名で、このうち104名(34.7%)がLSと診断された。三分割交差検証データセットの平均確度はトレーニングセットが0.71、検証セットが0.68を示しており、CNN出力はLS発症群の方が健常者群より有意に高かった。開発コホートにおける平均AUCは0.84、臨床モデルの平均AUCは0.80であった。足底圧分布をベースとしたAIモデルはLSのスクリーニングに有用なツールであることが示された。

  • 診断に難渋した胸椎病的骨折の1例 Reviewed

    鈴木 摩耶, 豊田 宏光, 寺井 秀富, 玉井 孝司, 中村 博亮

    中部日本整形外科災害外科学会雑誌   66 ( 3 )   507 - 508   2023.05( ISSN:0008-9443

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    Publishing type:Research paper (scientific journal)  

    症例は54歳女性で、人間ドックにて全身に多発する骨硬化性病変を指摘され、精査目的に当院紹介となった。経過中に腰痛が出現し、MRIで第9胸椎に病的骨折を認めた。血液検査や骨生検では異常所見は認めず、入院後に硬性コルセット装着にて安静加療を行ったが、徐々に骨折部の圧壊の進行を認めたため、第21病日に第7~12胸椎の後方除圧固定術を施行した。術中迅速病理検査では急性骨髄炎の診断であったが、術後の病理組織検査では悪性リンパ腫を否定できず、その後の精査結果よりSAPHO症候群の診断に至った。

  • MRIの予後不良因子を持たない新鮮骨粗鬆症性椎体骨折の保存加療における腰痛遺残リスク Reviewed

    岩前 真由, 寺井 秀富, 玉井 孝司, 星野 雅俊, 高橋 真治, 馬野 雅之, 小林 祐人, 勝田 紘史, 金田 国一, 島田 永和, 中村 博亮

    Journal of Spine Research   14 ( 5 )   786 - 793   2023.05( ISSN:1884-7137

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    Publishing type:Research paper (scientific journal)  

    はじめに:新鮮OVFのうちMRI予後不良因子(T2強調像で高信号限局型,低信号広範囲型)がないにも関わらず腰痛が遺残した症例について検討した.対象と方法:後ろ向きコホート研究.対象はOVFに対し保存加療を選択し,6ヶ月以上経過観察できた55例(平均年齢75.1歳,女性47例).MRIの予後不良因子を有する症例,馬尾・神経根の圧排を認める症例は除外した.6ヶ月時の腰痛VAS≧40の症例を腰痛遺残群(16例),その他を対照群(39例)に群分けした.評価項目は,初診時のX線動態撮影(座位・仰臥位側面)や全脊柱X線各種パラメーター,腰痛/臀部痛VAS,ODIを用いた.結果:単変量解析にて,初診時の臀部痛VAS(p=0.002),椎体可動角(p=0.047),TK(p=0.046),LL(p=0.031)に有意差があった.以上の有意な項目に年齢,性別,初診時腰痛VASを加えた多変量解析の結果,初診時の臀部痛VASが独立した腰痛遺残の危険因子であった(調整Odds比=1.526,p=0.019).結語:OVF受傷後6ヶ月時の腰痛遺残の危険因子は,初診時の臀部痛であった.(著者抄録)

  • Deep Learning Algorithm for Identifying Cervical Cord Compression Due to Degenerative Canal Stenosis on Radiography. Reviewed

    Tamai K, Terai H, Hoshino M, Tabuchi H, Kato M, Toyoda H, Suzuki A, Takahashi S, Yabu A, Sawada Y, Iwamae M, Oka M, Nakaniwa K, Okada M, Nakamura H

    Spine   48 ( 8 )   519 - 525   2023.04( ISSN:0362-2436

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/BRS.0000000000004595

    PubMed

  • Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture. Reviewed

    Tamai K, Terai H, Nakamura H, Yokogawa N, Sasagawa T, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Watanabe K, Yamane J, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    Journal of clinical medicine   12 ( 6 )   2023.03( ISSN:2077-0383

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    DOI: 10.3390/jcm12062387

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  • Effects of Dementia on Outcomes after Cervical Spine Injuries in Elderly Patients: Evaluation of 1512 Cases in a Nationwide Multicenter Study in Japan. Reviewed

    Yamada Y, Yokogawa N, Kato S, Sasagawa T, Tsuchiya H, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Yamane J, Nori S, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Watanabe K

    Journal of clinical medicine   12 ( 5 )   2023.02( ISSN:2077-0383

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    DOI: 10.3390/jcm12051867

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  • Characteristics of the cervical spine and cervical cord injuries in older adults with cervical ossification of the posterior longitudinal ligament. Reviewed

    Okuwaki S, Funayama T, Koda M, Eto F, Yamaji A, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    Scientific reports   13 ( 1 )   2689   2023.02

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    DOI: 10.1038/s41598-023-29877-2

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  • Relationship between body mass index and spinal pathology in community-dwelling older adults. Reviewed

    Takeuchi Y, Takahashi S, Ohyama S, Hori Y, Tsujio T, Kotake S, Yabu A, Hoshino M, Terai H, Kobayashi A, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   32 ( 2 )   428 - 435   2023.02( ISSN:0940-6719

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    DOI: 10.1007/s00586-022-07495-2

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  • Periostin increased by mechanical stress upregulates interleukin-6 expression in the ligamentum flavum. Reviewed

    Yabu A, Suzuki A, Hayashi K, Hori Y, Terai H, Orita K, Habibi H, Salimi H, Kono H, Toyoda H, Maeno T, Takahashi S, Tamai K, Ozaki T, Iwamae M, Ohyama S, Imai Y, Nakamura H

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology   37 ( 2 )   e22726   2023.02( ISSN:0892-6638

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    DOI: 10.1096/fj.202200917RR

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  • Less-invasive decompression procedures can reduce risk of reoperation for lumbar spinal stenosis with diffuse idiopathic skeletal hyperostosis extended to the lumbar segment: analysis of two retrospective cohorts. Reviewed

    Yamada K, Toyoda H, Hyakumachi T, Abe Y, Takahashi S, Suzuki A, Terai H, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   32 ( 2 )   505 - 516   2023.02( ISSN:0940-6719

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    DOI: 10.1007/s00586-022-07496-1

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  • Influence of the timing of surgery for cervical spinal cord injury without bone injury in the elderly: A retrospective multicenter study. Reviewed

    Nori S, Watanabe K, Takeda K, Yamane J, Kono H, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kiyasu K, Iizuka Y, Takasawa E, Funao H, Kaito T, Yoshii T, Ishihara M, Okada S, Imagama S, Kato S

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   2023.01( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2023.01.004

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  • Risk Factors for Early Mortality in Older Patients with Traumatic Cervical Spine Injuries-A Multicenter Retrospective Study of 1512 Cases. Reviewed

    Kobayashi M, Yokogawa N, Kato S, Sasagawa T, Tsuchiya H, Nakashima H, Segi N, Ito S, Funayama T, Eto F, Yamaji A, Yamane J, Nori S, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Kuroda A, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Watanabe K

    Journal of clinical medicine   12 ( 2 )   2023.01( ISSN:2077-0383

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    DOI: 10.3390/jcm12020708

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  • 私論 医療における確率について思うこと Reviewed

    寺井 秀富

    整形外科   74 ( 1 )   32 - 32   2023.01( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j_seikei74_32

  • Management of Antithrombotic Drugs before Elective Spine Surgery: A Nationwide Web-based Questionnaire Survey in Japan Reviewed

    Tezuka Fumitake, Sakai Toshinori, Imagama Shiro, Takahashi Hiroshi, Takaso Masashi, Aizawa Toshimi, Otani Koji, Okuda Shinya, Kato Satoshi, Kanemura Tokumi, Kawaguchi Yoshiharu, Konishi Hiroaki, Suda Kota, Terai Hidetomi, Nakanishi Kazuo, Nishida Kotaro, Machino Masaaki, Miyakoshi Naohisa, Murakami Hideki, Yamato Yu, Yukawa Yasutsugu, Medical Safety Promotion Committee of The Japanese Society for Spine Surgery and Related Research

    Spine Surgery and Related Research   advpub ( 0 )   2023( eISSN:2432261X

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    <p><b>Introduction: </b>The number of patients on antithrombotic drugs for coronary heart disease or cerebrovascular disease has been increasing with the aging of society. We occasionally need to decide whether to continue or discontinue antithrombotic drugs before spine surgery. The purpose of this study is to understand the current perioperative management of antithrombotic drugs before elective spine surgery in Japan.</p><p><b>Methods: </b>In 2021, members of the Japanese Society for Spine Surgery and Related Research (JSSR) were asked to complete a web-based questionnaire survey that included items concerning the respondents' surgical experience, their policy regarding discontinuation or continuation of antithrombotic drugs, their reasons for decisions concerning the management of antithrombotic drugs, and their experience of perioperative complications related to the continuation or discontinuation of these drugs.</p><p><b>Results: </b>A total of 1,181 spine surgeons returned completed questionnaires, giving a response rate of 32.0%. JSSR board-certified spine surgeons comprised 75.1% of the respondents. Depending on the management policy regarding antithrombotic drugs for each comorbidity, approximately 73% of respondents discontinued these drugs before elective spine surgery, and about 80% also discontinued anticoagulants. Only 4%–5% of respondents reported continuing antiplatelet drugs, and 2.5% reported continuing anticoagulants. Among the respondents who discontinued antiplatelet drugs, 20.4% reported having encountered cerebral infarction and 3.7% reported encountering myocardial infarction; among those who discontinued anticoagulants, 13.6% reported encountering cerebral embolism and 5.4% reported encountering pulmonary embolism. However, among the respondents who continued antiplatelet drugs and those who continued anticoagulants, 26.3% and 27.2%, respectively, encountered an unexpected increase in intraoperative bleeding, and 10.3% and 8.7%, respectively, encountered postoperative spinal epidural hematoma requiring emergency surgery.</p><p><b>Conclusions:</b></p><p>Our findings indicate that, in principle, >70% of JSSR members discontinue antithrombotic drugs before elective spine surgery. However, those with a discontinuation policy have encountered thrombotic complications, while those with a continuation policy have encountered hemorrhagic complications.</p>

    DOI: 10.22603/ssrr.2023-0015

  • Epidemiology of Cervical Fracture/Cervical Spinal Cord Injury and Changes in Surgical Treatment Modalities in Elderly Individuals During a 10-year Period: A Nationwide Multicenter Study in Japan Reviewed

    Segi N.

    Global Spine Journal   2023( ISSN:21925682

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    DOI: 10.1177/21925682231151643

  • Efficacy of Early Rehabilitation for Severe Coronavirus Disease 2019 Pneumonia: Factor Analysis Using Machine Learning

    Ikebuchi Mitsuhiko, Ohta Yoichi, Minoda Yukihide, Toki Akiko, Nakatsuchi Tamotsu, Terai Hidetomi, Nakamura Hiroaki, Kato Ryoichi, Nakajima Sigeyoshi

    Progress in Rehabilitation Medicine   8 ( 0 )   20230027   2023( eISSN:24321354

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    <p><b>Objectives: </b>Patients with severe coronavirus disease 2019 (COVID-19) who develop pneumonia face the risk of ventilatory muscle disuse in the acute phase, which can result in persistent respiratory impairments in the subacute phase. Although rehabilitation during the acute phase is considered effective, there are limited reports on this topic. Therefore, this study aimed to investigate the effectiveness of acute-phase rehabilitation in patients with severe COVID-19.</p><p><b>Methods: </b>The study included 57 patients (45 men and 12 women; mean age: 63.2±12.1 years) admitted between April and June 2021, all of whom required intubation for respiratory management. Among them, 34 patients underwent acute-phase rehabilitation interventions based on the early goal-directed mobilization protocol. The primary objectives were to assess the occurrence of medical accidents related to acute-phase rehabilitation and evaluate their impact on survival and mobility upon hospital discharge. Statistical techniques and machine learning algorithms were employed for data analysis.</p><p><b>Results: </b>Remarkably, no medical accidents occurred during the acute-phase rehabilitation among the patients. Furthermore, our findings indicated that acute-phase rehabilitation did not influence survival outcomes. However, it did have a positive impact on the mobility of patients upon hospital discharge.</p><p><b>Conclusions: </b>Acute-phase rehabilitation can be safely administered to patients with severe COVID-19 by following an early goal-directed mobilization protocol. This approach may also contribute to improved activities of daily living after discharge.</p>

    DOI: 10.2490/prm.20230027

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  • Efficacy of Early Rehabilitation for Severe Coronavirus Disease 2019 Pneumonia: Factor Analysis Using Machine Learning(タイトル和訳中) Reviewed

    Ikebuchi Mitsuhiko, Ohta Yoichi, Minoda Yukihide, Toki Akiko, Nakatsuchi Tamotsu, Terai Hidetomi, Nakamura Hiroaki, Kato Ryoichi, Nakajima Sigeyoshi

    Progress in Rehabilitation Medicine   8   1 - 15   2023

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  • Effect of low body mass index on clinical recovery after fusion surgery for osteoporotic vertebral fracture: A retrospective, multicenter study of 237 cases. Reviewed

    Inoue G, Miyagi M, Saito W, Shirasawa E, Uchida K, Hosogane N, Watanabe K, Katsumi K, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Nojiri K, Suzuki S, Okada E, Ueda S, Hikata T, Shiono Y, Watanabe K, Terai H, Tamai K, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Ohtori S, Furuya T, Orita S, Inage K, Yoshii T, Ushio S, Funao H, Isogai N, Harimaya K, Okada S, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kiyasu K, Imagama S, Ando K, Kobayashi K, Sakai D, Tanaka M, Kimura A, Inoue H, Nakano A, Ikegami S, Shimizu M, Futatsugi T, Kakutani K, Yurube T, Nakanishi K, Oshima M, Uei H, Aoki Y, Takahata M, Iwata A, Endo H, Seki S, Murakami H, Kato S, Yoshioka K, Hongo M, Abe T, Tsukanishi T, Takaso M, Ishii K

    Medicine   101 ( 52 )   e32330   2022.12( ISSN:0025-7974

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    DOI: 10.1097/MD.0000000000032330

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  • The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force Reviewed

    Wang Q.S.

    Nature Communications   13 ( 1 )   2022.12

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    DOI: 10.1038/s41467-022-32276-2

  • Exome Sequencing Reveals De Novo Variants in Congenital Scoliosis. Reviewed

    Murakami K, Kikugawa S, Seki S, Terai H, Suzuki T, Nakano M, Takahashi J, Nakamura Y

    Journal of pediatric genetics   11 ( 4 )   287 - 291   2022.12( ISSN:2146-4596

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    DOI: 10.1055/s-0041-1726282

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  • Prevalence, risk factors, and potential symptoms of hyponatremia after spinal surgery in elderly patients. Reviewed

    Kinoshita Y, Tamai K, Oka M, Habibi H, Terai H, Hoshino M, Toyoda H, Suzuki A, Takahashi S, Nakamura H

    Scientific reports   12 ( 1 )   18622   2022.11

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    DOI: 10.1038/s41598-022-23583-1

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  • Increased Surgical Experience in Microendoscopic Spinal Surgery Can Reduce Development of Postoperative Spinal Epidural Hematoma and Improve the Clinical Outcomes. Reviewed

    Iwamae M, Tamai K, Kaneda K, Terai H, Katsuda H, Shimada N, Nakamura H

    Journal of clinical medicine   11 ( 21 )   2022.11( ISSN:2077-0383

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    DOI: 10.3390/jcm11216495

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  • Real-World Data Analysis of Pembrolizumab Monotherapy for NSCLC Using Japanese Postmarketing All-Case Surveillance Data Reviewed

    Terai H.

    JTO Clinical and Research Reports   3 ( 11 )   2022.11

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    DOI: 10.1016/j.jtocrr.2022.100404

  • 特集 整形外科領域における人工知能の応用 各論 人工知能を活用した骨粗鬆症性椎体骨折の画像診断補助システム-MR画像における新鮮椎体骨折の識別 Reviewed

    藪 晋人, 星野 雅俊, 田淵 仁志, 高橋 真治, 寺井 秀富, 升本 浩紀, 前野 考史, 岩前 真由, 豊田 宏光, 鈴木 亨暢, 玉井 孝司, 猪瀬 弘之, 吉井 俊貴, 大川 淳, 中村 博亮

    臨床整形外科   57 ( 10 )   1205 - 1211   2022.10( ISSN:05570433 ( eISSN:18821286

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    DOI: 10.11477/mf.1408202457

  • Machine-learning-based approach for nonunion prediction following osteoporotic vertebral fractures. Reviewed

    Takahashi S, Terai H, Hoshino M, Tsujio T, Kato M, Toyoda H, Suzuki A, Tamai K, Yabu A, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   2022.10( ISSN:0940-6719

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    DOI: 10.1007/s00586-022-07431-4

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  • 【整形外科領域における人工知能の応用】人工知能を活用した骨粗鬆症性椎体骨折の画像診断補助システム MR画像における新鮮椎体骨折の識別 Reviewed

    藪 晋人, 星野 雅俊, 田淵 仁志, 高橋 真治, 寺井 秀富, 升本 浩紀, 前野 考史, 岩前 真由, 豊田 宏光, 鈴木 亨暢, 玉井 孝司, 猪瀬 弘之, 吉井 俊貴, 大川 淳, 中村 博亮

    臨床整形外科   57 ( 10 )   1205 - 1211   2022.10( ISSN:0557-0433

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    <文献概要>畳み込みニューラルネットワーク(CNN)を用いてMR画像(T1強調画像,矢状断)による新鮮骨粗鬆症性椎体骨折(OVF)の診断を行い,その精度を2人の脊椎外科医と比較した.新鮮OVFの診断においてCNNのROC曲線下面積は0.949であった.感度,特異性および精度は(CNN/脊椎外科医1/脊椎外科医2)感度:0.881/0.881/1.000,特異度:0.879/0.862/0.655,精度:0.880/0.870/0.800であった.MR画像を用いた新鮮OVF診断において,CNN分類器の診断能は良好であり,また脊椎外科医と同等であった.

  • Factors Affecting the Waiting Time from Injury to Surgery in Elderly Patients with a Cervical Spine Injury: A Japanese Multicenter Survey. Reviewed

    Uehara M, Ikegami S, Takizawa T, Oba H, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Kato S

    World neurosurgery   166   e815 - e822   2022.10( ISSN:1878-8750

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    DOI: 10.1016/j.wneu.2022.07.104

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  • Differences in clinical characteristics of cervical spine injuries in older adults by external causes: a multicenter study of 1512 cases. Reviewed

    Yokogawa N, Kato S, Sasagawa T, Hayashi H, Tsuchiya H, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Nori S, Yamane J, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kakutani K, Kakiuchi Y, Kiyasu K, Tominaga H, Tokumoto H, Iizuka Y, Takasawa E, Akeda K, Takegami N, Funao H, Oshima Y, Kaito T, Sakai D, Yoshii T, Ohba T, Otsuki B, Seki S, Miyazaki M, Ishihara M, Okada S, Imagama S, Watanabe K

    Scientific reports   12 ( 1 )   15867   2022.09

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    DOI: 10.1038/s41598-022-19789-y

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  • DOCK2 is involved in the host genetics and biology of severe COVID-19 Reviewed

    Namkoong H.

    Nature   609 ( 7928 )   754 - 760   2022.09( ISSN:00280836

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    DOI: 10.1038/s41586-022-05163-5

  • Postoperative Physical Therapy Program Focused on Low Back Pain Can Improve Treatment Satisfaction after Minimally Invasive Lumbar Decompression. Reviewed

    Terai H, Tamai K, Kaneda K, Omine T, Katsuda H, Shimada N, Kobayashi Y, Nakamura H

    Journal of clinical medicine   11 ( 19 )   2022.09( ISSN:2077-0383

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    DOI: 10.3390/jcm11195566

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  • Change in Physical and Mental Quality-of-Life between the Short- and Mid-Term Periods after Cervical Laminoplasty for Cervical Spondylotic Myelopathy: A Retrospective Cohort Study with Minimum 5 Years Follow-up. Reviewed

    Tamai K, Suzuki A, Terai H, Kato M, Toyoda H, Takahashi S, Yabu A, Sawada Y, Iwamae M, Nakamura H

    Journal of clinical medicine   11 ( 17 )   2022.09( ISSN:2077-0383

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    DOI: 10.3390/jcm11175230

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  • A multicenter study of 1-year mortality and walking capacity after spinal fusion surgery for cervical fracture in elderly patients. Reviewed

    Sasagawa T, Yokogawa N, Hayashi H, Tsuchiya H, Ando K, Nakashima H, Segi N, Watanabe K, Nori S, Takeda K, Furuya T, Yunde A, Ikegami S, Uehara M, Suzuki H, Imajo Y, Funayama T, Eto F, Yamaji A, Hashimoto K, Onoda Y, Kakutani K, Kakiuchi Y, Suzuki N, Kato K, Terashima Y, Hirota R, Yamada T, Hasegawa T, Kawaguchi K, Haruta Y, Seki S, Tonomura H, Sakata M, Uei H, Sawada H, Tominaga H, Tokumoto H, Kaito T, Iizuka Y, Takasawa E, Oshima Y, Terai H, Tamai K, Otsuki B, Miyazaki M, Nakajima H, Nakanishi K, Misaki K, Inoue G, Kiyasu K, Akeda K, Takegami N, Yoshii T, Ishihara M, Okada S, Aoki Y, Harimaya K, Murakami H, Ishii K, Ohtori S, Imagama S, Kato S

    BMC musculoskeletal disorders   23 ( 1 )   798   2022.08

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    DOI: 10.1186/s12891-022-05752-5

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  • Decreased daily exercise since the COVID-19 pandemic and the deterioration of health-related quality of life in the elderly population: a population-based cross-sectional study. Reviewed

    Tamai K, Terai H, Takahashi S, Katsuda H, Shimada N, Habibi H, Nakamura H

    BMC geriatrics   22 ( 1 )   678   2022.08

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    DOI: 10.1186/s12877-022-03316-9

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  • 特集 脊椎・脊髄感染症の診断と治療-最近の知見 脊椎感染症の手術療法 Reviewed

    寺井 秀富, 中村 博亮

    脊椎脊髄ジャーナル   35 ( 3 )   153 - 160   2022.08( ISSN:09144412

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    DOI: 10.11477/mf.5002201812

  • 【脊椎・脊髄感染症の診断と治療-最近の知見】脊椎感染症の手術療法 Reviewed

    寺井 秀富, 中村 博亮

    脊椎脊髄ジャーナル   35 ( 3 )   153 - 160   2022.08( ISSN:0914-4412

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    <文献概要>はじめに 近年,人口の高齢化に伴って脊椎感染症の発生も増加している.脊椎感染症の治療戦略は,基本的に適切な抗菌薬投与と局所安静による保存療法である.しかし,抗菌薬投与のみで感染を鎮静化できない場合,疼痛を制御できない場合,神経障害を生じている場合,椎体破壊が進行し脊柱不安定性を生じる場合などでは手術加療を検討しなければならない.手術療法として,ドレナージ,後方除圧術,後方固定術,前方固定術などさまざまな方法が報告されている.個々の症例の状態に応じた手術療法を選択すべきであるが,骨粗鬆症,糖尿病といった併存症の多い高齢者,ステロイド・免疫抑制剤の使用や血液透析患者などの易感染性宿主など本来手術を避けたい症例にこそ手術加療が必要になることも多く,可能な限り低侵襲な治療法が望まれる.近年,経皮的スクリューや低侵襲前方アプローチといった低侵襲脊椎手術の発展とともに,脊椎感染症の治療も変化してきている.本稿では,脊椎感染症に対する手術療法としてドレナージ,後方除圧,後方固定,前方固定(椎体間固定)の各手技について概説する.

  • Is Blood Loss Greater in Elderly Patients under Antiplatelet or Anticoagulant Medication for Cervical Spine Injury Surgery?: A Japanese Multicenter Survey(和訳中) Reviewed

    Uehara Masashi, Ikegami Shota, Takizawa Takashi, Oba Hiroki, Yokogawa Noriaki, Sasagawa Takeshi, Ando Kei, Nakashima Hiroaki, Segi Naoki, Funayama Toru, Eto Fumihiko, Yamaji Akihiro, Watanabe Kota, Nori Satoshi, Takeda Kazuki, Furuya Takeo, Orita Sumihisa, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Terashima Yoshinori, Hirota Ryosuke, Suzuki Hidenori, Imajo Yasuaki, Tonomura Hitoshi, Sakata Munehiro, Hashimoto Ko, Onoda Yoshito, Kawaguchi Kenichi, Haruta Yohei, Suzuki Nobuyuki, Kato Kenji, Uei Hiroshi, Sawada Hirokatsu, Nakanishi Kazuo, Misaki Kosuke, Terai Hidetomi, Tamai Koji, Shirasawa Eiki, Inoue Gen, Kakutani Kenichiro, Kakiuchi Yuji, Kiyasu Katsuhito, Tominaga Hiroyuki, Tokumoto Hiroto, Iizuka Yoichi, Takasawa Eiji, Akeda Koji, Takegami Norihiko, Funao Haruki, Oshima Yasushi, Kaito Takashi, Sakai Daisuke, Yoshii Toshitaka, Ohba Tetsuro, Otsuki Bungo, Seki Shoji, Miyazaki Masashi, Ishihara Masayuki, Okada Seiji, Aoki Yasuchika, Harimaya Katsumi, Murakami Hideki, Ishii Ken, Ohtori Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   6 ( 4 )   366 - 372   2022.07

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  • Characteristics of low back pain and its countermeasures among elderly population living in sub-urban area of Japan -Based on the results obtained from the longitudinal analysis of the Shiraniwa Study- Reviewed

    Ohyama Shoichiro, Takahashi Shinji, Hoshino Masatoshi, Hori Yusuke, Yabu Akito, Tsujio Tadao, Takeuchi Yuichi, Terai Hidetomi, Nakamura Hiroaki

    Journal of Spine Research   13 ( 6 )   809 - 817   2022.06( ISSN:18847137 ( eISSN:24351563

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    DOI: 10.34371/jspineres.2022-0602

  • A deep convolutional neural network for diagnosing osteoporotic vertebral fractures Reviewed

    Yabu Akito, Takahashi Shinji, Terai Hidetomi, Hoshino Masatoshi, Nakamura Hiroaki

    Journal of Spine Research   13 ( 6 )   844 - 850   2022.06( ISSN:18847137 ( eISSN:24351563

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    DOI: 10.34371/jspineres.2022-0607

  • Does surgery improve neurological outcomes in older individuals with cervical spinal cord injury without bone injury? A multicenter study. Reviewed

    Nori S, Watanabe K, Takeda K, Yamane J, Kono H, Yokogawa N, Sasagawa T, Ando K, Nakashima H, Segi N, Funayama T, Eto F, Yamaji A, Furuya T, Yunde A, Nakajima H, Yamada T, Hasegawa T, Terashima Y, Hirota R, Suzuki H, Imajo Y, Ikegami S, Uehara M, Tonomura H, Sakata M, Hashimoto K, Onoda Y, Kawaguchi K, Haruta Y, Suzuki N, Kato K, Uei H, Sawada H, Nakanishi K, Misaki K, Terai H, Tamai K, Shirasawa E, Inoue G, Kiyasu K, Iizuka Y, Takasawa E, Funao H, Kaito T, Yoshii T, Ishihara M, Okada S, Imagama S, Kato S

    Spinal cord   2022.06( ISSN:1362-4393

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    DOI: 10.1038/s41393-022-00818-6

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  • Development of locomotive syndrome in elderly population after COVID-19 outbreak: A population-based cross-sectional study with over 12,000 participants. Reviewed

    Terai H, Tamai K, Takahashi S, Katsuda H, Shimada N, Hori Y, Kobayashi Y, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   2022.06( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2022.05.012

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  • Decreased muscle mass and strength affected spinal sagittal malalignment. Reviewed

    Miyagi M, Inoue G, Hori Y, Inage K, Murata K, Kawakubo A, Fujimaki H, Koyama T, Yokozeki Y, Mimura Y, Takahashi S, Ohyama S, Terai H, Hoshino M, Suzuki A, Tsujio T, Dohzono S, Sasaoka R, Toyoda H, Orita S, Eguchi Y, Shiga Y, Furuya T, Maki S, Shirasawa E, Saito W, Imura T, Nakazawa T, Uchida K, Ohtori S, Nakamura H, Takaso M

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   31 ( 6 )   1431 - 1437   2022.06( ISSN:0940-6719

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    DOI: 10.1007/s00586-022-07151-9

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  • 【超高齢社会における腰痛診療】Shiraniwa Studyからみた高齢者腰痛の特徴とその対策 Reviewed

    大山 翔一朗, 高橋 真治, 星野 雅俊, 堀 悠介, 藪 晋人, 辻尾 唯雄, 竹内 雄一, 寺井 秀富, 中村 博亮

    Journal of Spine Research   13 ( 6 )   809 - 817   2022.06( ISSN:1884-7137

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    我々は2016年8月より都市圏在住65歳以上の高齢者409名を対象に,腰痛を含めた身体症状や,身体機能評価,画像検査からなる観察研究(Shiraniwa Study)を行っている.その横断解析の結果より,高齢者腰痛の独立した関連因子は脊柱インバランス(SVA>95),肥満(BMI≧25.0),既存椎体骨折,不安の強さであり,腰痛対策としてこれらに介入することが有効と考えた.縦断的に脊柱インバランス進行を生じた高齢者の特徴を解析したところ,ロコモ度2は独立した脊柱インバランス進行の予測因子であった.また,経時的にロコモ度が改善した高齢者は体重減少を認めていたことから,減量はロコモ度改善を介して脊柱インバランス進行の抑制に寄与する可能性があると考えられた.減量は高齢者腰痛の関連因子である,肥満,脊柱インバランスの両者に影響することから,有効な高齢者腰痛対策となり得ると注目している.(著者抄録)

  • 【新技術の腰痛診療への応用】人工知能技術を活用した骨粗鬆症性椎体骨折の画像診断補助システム Reviewed

    藪 晋人, 高橋 真治, 寺井 秀富, 星野 雅俊, 中村 博亮

    Journal of Spine Research   13 ( 6 )   844 - 850   2022.06( ISSN:1884-7137

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    高齢化社会の進行に伴い,骨粗鬆症患者数も増加の一途をたどっている.骨粗鬆症性椎体骨折は高齢者のADLやQOLを低下させるため,早期に適切な治療介入を行う必要があり,精度の高い診断が重要となる.近年,人工知能による物体認識は畳み込みニューラルネットワーク(Convolutional neural network:CNN)の開発により著しく改善を認め,画像診断サポートツールに応用されている.過去に我々はCNNを用いてMR画像で新鮮椎体骨折を検出するシステムを構築した.本稿ではその研究成果を述べるとともに骨粗鬆症性椎体骨折に関する診断や画像診断サポートツールとしての人工知能の有用性についてレビューした.(著者抄録)

  • Mid-term changes in spinopelvic sagittal alignment in lumbar spinal stenosis with coexisting degenerative spondylolisthesis or scoliosis after minimally invasive lumbar decompression surgery: minimum five-year follow-up. Reviewed

    Salimi H, Toyoda H, Terai H, Yamada K, Hoshino M, Suzuki A, Takahashi S, Tamai K, Hori Y, Yabu A, Nakamura H

    The spine journal : official journal of the North American Spine Society   22 ( 5 )   819 - 826   2022.05( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2021.11.012

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  • Long-Term Outcomes in Elderly Patients After Deferral of Coronary Revascularization Guided by Fractional Flow Reserve. Reviewed

    Ueki Y, Kuramitsu S, Saigusa T, Senda K, Matsuo H, Horie K, Takashima H, Terai H, Kikuta Y, Ishihara T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Tsujita K, Masamura K, Doijiri T, Sasaki Y, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Kanemura N, Sonoda S, Yokoi H, Tanaka N, J-CONFIRM Investigators.

    Circulation journal : official journal of the Japanese Circulation Society   2022.03( ISSN:1346-9843

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    DOI: 10.1253/circj.CJ-21-1024

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  • Facet Joint Opening on Computed Tomography Is a Predictor of Poor Clinical Outcomes After Minimally Invasive Decompression Surgery for Lumbar Spinal Stenosis. Reviewed

    Yamada K, Toyoda H, Takahashi S, Tamai K, Suzuki A, Hoshino M, Terai H, Nakamura H

    Spine   47 ( 5 )   405 - 413   2022.03( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000004262

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  • Expression and function of fibroblast growth factor 1 in the hypertrophied ligamentum flavum of lumbar spinal stenosis. Reviewed

    Habibi H, Suzuki A, Hayashi K, Salimi H, Hori Y, Orita K, Yabu A, Terai H, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   27 ( 2 )   299 - 307   2022.03( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2021.01.004

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  • Expression and function of fibroblast growth factor 1 in the hypertrophied ligamentum flavum of lumbar spinal stenosis(和訳中) Reviewed

    Habibi Hasibullah, Suzuki Akinobu, Hayashi Kazunori, Salimi Hamidullah, Hori Yusuke, Orita Kumi, Yabu Akito, Terai Hidetomi, Nakamura Hiroaki

    Journal of Orthopaedic Science   27 ( 2 )   299 - 307   2022.03( ISSN:0949-2658

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  • 【アスリートの椎間板-椎間板を制するものは腰痛を制す-】アスリートの椎間板 ラグビー選手の椎間板 Reviewed

    寺井 秀富, 橋本 祐介, 西野 壱哉, 中村 博亮

    臨床スポーツ医学   39 ( 3 )   256 - 261   2022.03( ISSN:0289-3339

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  • Anti-seizure effects of medicinal plants in Malawi on pentylenetetrazole-induced seizures in zebrafish larvae. Reviewed

    Gwedela MNV, Terai H, Lampiao F, Matsunami K, Aizawa H

    Journal of ethnopharmacology   284   114763   2022.02( ISSN:0378-8741

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    DOI: 10.1016/j.jep.2021.114763

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  • Artificial intelligence model to identify elderly patients with locomotive syndrome: A cross-section study. Reviewed

    Takahashi S, Nonomiya Y, Terai H, Hoshino M, Ohyama S, Shintani A, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   2022.02( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2022.01.010

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  • A deep learning algorithm to identify cervical ossification of posterior longitudinal ligaments on radiography. Reviewed

    Tamai K, Terai H, Hoshino M, Yabu A, Tabuchi H, Sasaki R, Nakamura H

    Scientific reports   12 ( 1 )   2113   2022.02

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    DOI: 10.1038/s41598-022-06140-8

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  • Incidence of postoperative progressive segment degeneration at decompression and adjacent segments after minimally invasive lumbar decompression surgery: a 5-year follow-up study. Reviewed

    Habibi H, Toyoda H, Terai H, Yamada K, Hoshino M, Suzuki A, Takahashi S, Tamai K, Salimi H, Hori Y, Yabu A, Nakamura H

    Journal of neurosurgery. Spine   37 ( 1 )   1 - 8   2022.02( ISSN:1547-5654

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    DOI: 10.3171/2021.12.SPINE211151

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  • Association of Guideline-Directed Medical Therapy Adherence with Outcomes After Fractional Flow Reserve-Based Deferral of Revascularization. Reviewed

    Ishii M, Kuramitsu S, Yamanaga K, Matsuo H, Horie K, Takashima H, Terai H, Kikuta Y, Ishihara T, Saigusa T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Masamura K, Doijiri T, Toyota F, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Kanemura N, Sonoda S, Yokoi H, Tanaka N, Tsujita K, J- CONFIRM Registry Investigators .

    European heart journal. Cardiovascular pharmacotherapy   2022.02( ISSN:2055-6837

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    DOI: 10.1093/ehjcvp/pvac008

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  • Five-Year Outcomes After Fractional Flow Reserve-Based Deferral of Revascularization in Chronic Coronary Syndrome: Final Results From the J-CONFIRM Registry. Reviewed

    Kuramitsu S, Matsuo H, Shinozaki T, Horie K, Takashima H, Terai H, Kikuta Y, Ishihara T, Saigusa T, Sakamoto T, Suematsu N, Shiono Y, Asano T, Tsujita K, Masamura K, Doijiri T, Toyota F, Ogita M, Kurita T, Matsuo A, Harada K, Yaginuma K, Sonoda S, Yokoi H, Tanaka N, J-CONFIRM Investigators.

    Circulation. Cardiovascular interventions   15 ( 2 )   e011387   2022.02( ISSN:1941-7640

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    DOI: 10.1161/CIRCINTERVENTIONS.121.011387

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  • The health-related quality of life of patients with musculoskeletal disorders after the COVID-19 pandemic. Reviewed

    Terai H, Tamai K, Takahashi S, Hori Y, Iwamae M, Ohyama S, Yabu A, Hoshino M, Nakamura H

    International orthopaedics   46 ( 2 )   189 - 195   2022.02( ISSN:0341-2695

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    DOI: 10.1007/s00264-021-05256-2

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  • Impact of the COVID-19 Pandemic on Elderly Patients with Spinal Disorders. Reviewed

    Terai H, Takahashi S, Tamai K, Hori Y, Iwamae M, Hoshino M, Ohyama S, Yabu A, Nakamura H

    Journal of clinical medicine   11 ( 3 )   2022.01

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    DOI: 10.3390/jcm11030602

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  • Comparison of Medical Costs, Including Nursing Care and Informal Care Costs, Involved in Balloon Kyphoplasty and Conservative Treatment for Osteoporotic Vertebral Fractures Reviewed

    Takahashi Shinji, Terai Hidetomi, Hoshino Masatoshi, Nakamura Hiroaki

    Journal of Spine Research   13 ( 1 )   57 - 64   2022.01( ISSN:18847137 ( eISSN:24351563

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    <p><b>Introduction: </b>Osteoporotic vertebral fracture (OVF) is one of the most common fractures among the elderly, and its impact on the cost of care is a concern. Balloon kyphoplasty (BKP) is a widely used treatment for OVF. The purpose of this study is to estimate the cost of conservative treatment and BKP, including the cost of nursing care and the loss of productivity of caregivers, based on previous reports.</p><p><b>Methods: </b>For the distribution of activities of daily living (ADLs) after OVF, we used data from our multicenter prospective study that evaluated BKP and conservative treatment for 6 months in patients aged ≥65 years within 2 months of the onset. Estimates of nursing care costs and informal care costs were estimated mainly based on data published by the Ministry of Health, Labor and Welfare.</p><p><b>Results: </b>To compare nursing care costs, we summed up the distribution of ADLs, the level of nursing care required, and the level of independence in daily living at the end of 6 months of treatment. The per capita nursing care costs by level of nursing care required at the end of 6 months were 39,497 yen/month in the BKP group and 58,298 yen/month in the conservative therapy group with a difference of 18,801 yen/month. The per capita informal care costs by level of care required at the end of 6 months of treatment were 35,722 yen/month in the BKP group and 44,102 yen/month in the conservative therapy group, with a difference of 8,380 yen/month.</p><p><b>Conclusions: </b>For patients with OVF, improvement of ADL via BKP may reduce the cost of care and caregiver productivity loss.</p>

    DOI: 10.34371/jspineres.2021-0041

    CiNii Article

  • 臨床室 脊椎術後に発生した鉱質コルチコイド反応性低ナトリウム血症の1例 Reviewed

    木下 右貴, 玉井 孝司, 寺井 秀富, 豊田 宏光, 鈴木 亨暢, 中村 博亮

    整形外科   73 ( 1 )   28 - 31   2022.01( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j_seikei73_28

  • Improvements in Mental Well-Being and its Predictive Factors in Patients who Underwent Cervical versus Lumbar Decompression Surgery(和訳中) Reviewed

    Tamai Koji, Suzuki Akinobu, Toyoda Hiromitsu, Terai Hidetomi, Hoshino Masatoshi, Takahashi Shinji, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine Surgery and Related Research   6 ( 1 )   10 - 16   2022.01

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  • 臨床室 脊椎術後に発生した鉱質コルチコイド反応性低ナトリウム血症の1例 Reviewed

    木下 右貴, 玉井 孝司, 寺井 秀富, 豊田 宏光, 鈴木 亨暢, 中村 博亮

    整形外科   73 ( 1 )   28 - 31   2022.01( ISSN:0030-5901

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    症例は77歳女性で、両下肢痛、両下肢しびれ、腰痛を主訴とした。腰部脊椎管狭窄症の診断でL4/L5前側方進入椎体間固定術を施行した。術後3日に低Na血症(129mEq/l)を認め、食塩経口負荷で一旦改善傾向を認めたが、術後12日のリハビリテーション後よりNa 116mEq/lの重篤な低Na血症を認めた。アンジオテンシンII受容体拮抗薬系降圧薬とNSAIDsを定期内服し、初回の腰椎後方除圧術後にも低Na血症で入院加療した既往が判明し、鉱質コルチコイド反応性低Na血症の可能性を考えた。イルベサルタン・アムロジピンベシル酸塩配合、セレコキシブの内服を中止し、1.7%生理食塩水投与を開始した。翌日にNa 124mEq/lまで改善したため1.2%生理食塩水投与に変更し、術後17日より食塩経口負荷を、術後19日よりフルドロコルチゾン酢酸エステル投与を開始した。術後22日にNa 133mEq/lで自宅退院し、退院後4ヵ月でフルドロコルチゾン酢酸エステルを終了した。

  • 骨粗鬆症性椎体骨折に対するBalloon Kyphoplastyと保存治療の医療費の比較 介護費とインフォーマルケア費の検討 Reviewed

    高橋 真治, 寺井 秀富, 星野 雅俊, 中村 博亮

    Journal of Spine Research   13 ( 1 )   57 - 64   2022.01( ISSN:1884-7137

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    はじめに:骨粗鬆症性椎体骨折(OVF)は高齢者の多くが罹患する骨折であり介護費用に与える影響が懸念される.一方でBalloon kyphoplasty(BKP)はOVFに対して広く行われている治療の一つである.本研究目的は過去の報告をもとに介護費用及び介護者の生産性損失を含めた保存治療およびBKPの費用を推計することである.対象と方法:OVF後のADL分布は,新規にOVFを発症した受傷後2ヵ月以内の65歳以上の者を対象としてBKPあるいは保存治療を実施した6ヵ月間の多施設前向き研究のデータを使用した.介護費用の推計やインフォーマルケア費用の推計について,主に厚生労働省が公表しているデータを基に推計した.結果:介護費用は,治療実施6ヵ月後時点のADL分布と要介護度と日常生活自立度の分布を基に算出した.治療実施6ヵ月後時点の要介護度別の1人あたり介護費は,BKP群39,497円/月,保存療法群58,298円/月,差分18,801円/月であった.インフォーマルケア費用の比較として,治療実施6ヵ月後時点の要介護度別の1人あたりインフォーマルケア費用は,BKP群で35,722円/月,保存療法群で44,102円/月,差分は8,380円/月であった.結語:BKPによるADLの改善が,介護費用および介護者の生産性損失を削減する可能性がある.(著者抄録)

  • Improvements in Mental Well-Being and its Predictive Factors in Patients who Underwent Cervical versus Lumbar Decompression Surgery

    Tamai Koji, Suzuki Akinobu, Toyoda Hiromitsu, Terai Hidetomi, Hoshino Masatoshi, Takahashi Shinji, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine Surgery and Related Research   6 ( 1 )   10 - 16   2022( eISSN:2432261X

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    <p>Introduction: Mental well-being is essential for patient satisfaction. Therefore, a better understanding of the changes in the mental well-being of patients following spinal surgery can be useful to surgeons. We compared the 2-year postoperative change in the mental well-being of patients who underwent cervical and lumbar decompression surgery. Additionally, the predictive factors for improvement in mental well-being associated with both methods were evaluated.</p><p>Methods: The patients who underwent spinal decompression surgery and were followed >2 years postoperatively were enrolled (lumbar cohort: n=111, cervical cohort: n=121). The 36-item Short-Form Health Survey (SF-36) mental component summary (MCS) was set as the mental well-being parameter, and the minimal clinically important difference (MCID) was defined as 4.0. After adjusting the cervical and lumbar cohorts using propensity scores, the improvements in the MCS were compared between the groups using a mixed-effect model. To identify predictors for improvements, the correlation between the MCS changes and preoperative clinical scores was evaluated. Subsequently, multivariate linear regression was applied, which included variables with p<0.10 in the former analysis as explanatory variables, and the change of MCS as the objective variable.</p><p>Results: There were no significant differences in the MCS improvement between the adjusted cervical and lumbar cohorts; 47% and 49%, respectively, had MCS improvement score >MCIDs. However, predictors for the improvement were different between the two cohorts: SF-36 Social functioning in cervical surgery and lower back pain and SF-36 Role physical in lumbar surgery.</p><p>Conclusions: Although there was no significant difference in the improvement in the mental well-being between patients who underwent either cervical or lumbar decompression surgery, less than half of the patients in both groups achieved a meaningful improvement. Preoperative back pain and personal activity were independent predictors in the lumbar cohort, while social functioning was the only predictor in the cervical cohort.</p><p>Level of evidence: III</p>

    DOI: 10.22603/ssrr.2021-0060

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  • Prognostic Factors for Respiratory Dysfunction for Cervical Spinal Cord Injury and/or Cervical Fractures in Elderly Patients: A Multicenter Survey Reviewed

    Hirota R.

    Global Spine Journal   2022( ISSN:21925682

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    DOI: 10.1177/21925682221095470

  • Finding of the factors affecting the severity of COVID-19 based on mathematical models. Reviewed

    Qu J, Sumali B, Lee H, Terai H, Ishii M, Fukunaga K, Mitsukura Y, Nishimura T

    Scientific reports   11 ( 1 )   24224   2021.12

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    DOI: 10.1038/s41598-021-03632-x

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  • Electrophysiological and pharmacological characterization of spreading depolarization in the adult zebrafish tectum. Reviewed

    Terai H, Gwedela MNV, Kawakami K, Aizawa H

    Journal of neurophysiology   126 ( 6 )   1934 - 1942   2021.12( ISSN:0022-3077

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    DOI: 10.1152/jn.00343.2021

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  • Clinical Comparison of Combined Cortical Bone Trajectory and Transarticular Surface Screw Versus Standard Pedicle Screw Insertion by Wiltse Approach for L5 Isthmic Spondylolisthesis. Reviewed

    Terai H, Tamai K, Takahashi S, Umano M, Iwamae M, Toyoda H, Suzuki A, Hoshino M, Nakamura H

    Clinical spine surgery   34 ( 10 )   E580 - E587   2021.12( ISSN:2380-0186

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    DOI: 10.1097/BSD.0000000000001170

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  • 経験と考察 新型コロナウイルス感染症(COVID-19)流行による生活様式の変化に対して運動指導を希望する整形外科患者の特徴 Reviewed

    馬野 雅之, 寺井 秀富, 玉井 孝司, 勝田 紘史, 島田 永和, 中村 博亮

    整形外科   72 ( 13 )   1327 - 1332   2021.12( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j_seikei72_1327

  • A phase I/II study of osimertinib in EGFR exon 20 insertion mutation-positive non-small cell lung cancer. Reviewed

    Yasuda H, Ichihara E, Sakakibara-Konishi J, Zenke Y, Takeuchi S, Morise M, Hotta K, Sato M, Matsumoto S, Tanimoto A, Matsuzawa R, Kiura K, Takashima Y, Yano S, Koyama J, Fukushima T, Hamamoto J, Terai H, Ikemura S, Takemura R, Goto K, Soejima K

    Lung cancer (Amsterdam, Netherlands)   162   140 - 146   2021.12( ISSN:0169-5002

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    DOI: 10.1016/j.lungcan.2021.10.006

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  • 【高齢者の脊椎脆弱性骨折に対する最小侵襲手術】骨粗鬆症性椎体骨折の画像診断と治療戦略 Reviewed

    寺井 秀富

    整形外科最小侵襲手術ジャーナル   ( 101 )   10 - 16   2021.12( ISSN:1342-3991

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    超高齢社会の到来に伴い、すべての整形外科医にとって骨粗鬆症性椎体骨折は向き合わなければならない疾患となった。骨粗鬆症性椎体骨折は1つの疾患として呼称されているが、病期によって様々な症状と病態を呈し、それらを一括りにすることはできない。治療方法は病態に即した方法を選択しなければ十分な治療効果が望めないため、正確な病期・病態の把握が治療の第一歩となる。骨粗鬆症性椎体骨折の病期・病態の把握には症状や身体所見とあわせ、画像診断を欠かすことはできない。限られた医療資源のなかで必要な画像検査を取捨選択し、適切な治療方針を立てる必要がある。本稿では各病期・病態に応じた画像検査とその解釈を示し、どのように治療戦略を立てていくのかを解説する。(著者抄録)

  • 経験と考察 新型コロナウイルス感染症(COVID-19)流行による生活様式の変化に対して運動指導を希望する整形外科患者の特徴 Reviewed

    馬野 雅之, 寺井 秀富, 玉井 孝司, 勝田 紘史, 島田 永和, 中村 博亮

    整形外科   72 ( 13 )   1327 - 1332   2021.12( ISSN:0030-5901

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    2020年11〜12月に大阪府内で行われた大規模アンケート調査から、COVID-19流行以後の生活様式の変化に対して運動指導を希望する整形外科患者の特徴について分析した。その結果、運動指導の希望がある患者は高齢、女性、膝関節疾患や股関節疾患、外出頻度が低下した患者、運動頻度が低下した患者、運動頻度が増加した患者で有意に多かった。また、運動指導の希望がない患者でも運動習慣の低下が約1/3、ADLの増悪が約1割の患者に存在することが明らかになった。

  • Characteristics and Short-Term Surgical Outcomes of Patients with Recurrent Lumbar Disc Herniation after Percutaneous Laser Disc Decompression. Reviewed

    Terai H, Tamai K, Iwamae M, Kaneda K, Katsuda H, Shimada N, Nakamura H

    Medicina (Kaunas, Lithuania)   57 ( 11 )   2021.11( ISSN:1010-660X

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    DOI: 10.3390/medicina57111225

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  • Reductions in the Frequency of Going Out Due to the COVID-19 Pandemic Negatively Affect Patients with Spinal Disorders(和訳中) Reviewed

    Terai Hidetomi, Iwamae Masayoshi, Tamai Koji, Takahashi Shinji, Hori Yusuke, Ohyama Shoichiro, Yabu Akito, Hoshino Masatoshi, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 6 )   365 - 374   2021.11

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  • Percutaneous Endovascular Retrieval of Large Cement Leakage into the Right Atrium Following Cement-Augmented Pedicle Screw Instrumentation(和訳中) Reviewed

    Takahashi Shinji, Sohgawa Etsuji, Suzuki Akinobu, Yamamoto Akira, Sasaki Ryo, Tanaka Katsuaki, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Tamai Koji, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 6 )   446 - 449   2021.11

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  • Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol. Reviewed

    Nakagawara K, Namkoong H, Terai H, Masaki K, Tanosaki T, Shimamoto K, Lee H, Tanaka H, Okamori S, Kabata H, Chubachi S, Ikemura S, Kamata H, Yasuda H, Kawada I, Ishii M, Ishibashi Y, Harada S, Fujita T, Ito D, Bun S, Tabuchi H, Kanzaki S, Shimizu E, Fukuda K, Yamagami J, Kobayashi K, Hirano T, Inoue T, Kagyo J, Shiomi T, Ohgino K, Sayama K, Otsuka K, Miyao N, Odani T, Oyamada Y, Masuzawa K, Nakayama S, Suzuki Y, Baba R, Nakachi I, Kuwahara N, Ishiguro T, Mashimo S, Minematsu N, Ueda S, Manabe T, Funatsu Y, Koh H, Yoshiyama T, Saito F, Ishioka K, Takahashi S, Nakamura M, Goto A, Harada N, Kusaka Y, Nakano Y, Nishio K, Tateno H, Edahiro R, Takeda Y, Kumanogoh A, Kodama N, Okamoto M, Umeda A, Hagimura K, Sato T, Miyazaki N, Takemura R, Sato Y, Takebayashi T, Nakahara J, Mimura M, Ogawa K, Shimmura S, Negishi K, Tsubota K, Amagai M, Goto R, Ibuka Y, Hasegawa N, Kitagawa Y, Kanai T, Fukunaga K

    BMJ open respiratory research   8 ( 1 )   2021.11

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    DOI: 10.1136/bmjresp-2021-001015

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  • Prevalence of Restless Legs Syndrome and its Symptoms among Patients with Spinal Disorders. Reviewed

    Terai H, Toyoda H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Ohyama S, Yabu A, Nakamura H

    Journal of clinical medicine   10 ( 21 )   2021.10

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    DOI: 10.3390/jcm10215001

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  • Relationship between facet joint opening on CT and facet joint effusion on MRI in patients with lumbar spinal stenosis: analysis of a less invasive decompression procedure. Reviewed

    Yamada K, Toyoda H, Takahashi S, Tamai K, Suzuki A, Hoshino M, Terai H, Nakamura H

    Journal of neurosurgery. Spine   36 ( 3 )   1 - 9   2021.10( ISSN:1547-5654

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    DOI: 10.3171/2021.6.SPINE21721

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  • Using artificial intelligence to diagnose fresh osteoporotic vertebral fractures on magnetic resonance images. Reviewed

    Yabu A, Hoshino M, Tabuchi H, Takahashi S, Masumoto H, Akada M, Morita S, Maeno T, Iwamae M, Inose H, Kato T, Yoshii T, Tsujio T, Terai H, Toyoda H, Suzuki A, Tamai K, Ohyama S, Hori Y, Okawa A, Nakamura H

    The spine journal : official journal of the North American Spine Society   21 ( 10 )   1652 - 1658   2021.10( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2021.03.006

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  • Clinical Efficacy and Future Prospects of Immunotherapy in Lung Cancer. Reviewed

    Kinoshita T, Terai H, Yaguchi T

    Life (Basel, Switzerland)   11 ( 10 )   2021.09

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    DOI: 10.3390/life11101029

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  • Clinical outcomes of laminoplasty for patients with lysosomal storage disease including mucopolysaccharidosis and mucolipidoses: a retrospective cohort study. Reviewed

    Terai H, Tamai K, Hoshino M, Toyoda H, Suzuki A, Takahashi S, Hori Y, Yabu A, Nakamura H

    Orphanet journal of rare diseases   16 ( 1 )   401   2021.09

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    DOI: 10.1186/s13023-021-02031-9

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  • Clinical Outcomes of Minimally Invasive Posterior Decompression for Lumbar Spinal Stenosis with Degenerative Spondylolisthesis. Reviewed

    Kobayashi Y, Tamai K, Toyoda H, Terai H, Hoshino M, Suzuki A, Takahashi S, Hori Y, Yabu A, Nakamura H

    Spine   46 ( 18 )   1218 - 1225   2021.09( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000003997

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  • Direct Lateral Corpectomy and Reconstruction Using an Expandable Cage Improves Local Kyphosis but Not Global Sagittal Alignment. Reviewed

    Terai H, Takahashi S, Yasuda H, Konishi S, Maeno T, Kono H, Matsumura A, Namikawa T, Kato M, Hoshino M, Tamai K, Toyoda H, Suzuki A, Nakamura H

    Journal of clinical medicine   10 ( 17 )   2021.09

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    DOI: 10.3390/jcm10174012

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  • Impact of the COVID-19 pandemic on the development of locomotive syndrome. Reviewed

    Terai H, Hori Y, Takahashi S, Tamai K, Iwamae M, Hoshino M, Ohyama S, Yabu A, Nakamura H

    Journal of orthopaedic surgery (Hong Kong)   29 ( 3 )   23094990211060967   2021.09( ISSN:1022-5536

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    DOI: 10.1177/23094990211060967

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  • Can Conventional Magnetic Resonance Imaging Substitute Three-Dimensional Magnetic Resonance Imaging in the Diagnosis of Lumbar Foraminal Stenosis? Reviewed

    Hasib MM, Yamada K, Hoshino M, Yamada E, Tamai K, Takahashi S, Suzuki A, Toyoda H, Terai H, Nakamura H

    Asian spine journal   15 ( 4 )   472 - 480   2021.08( ISSN:1976-1902

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    DOI: 10.31616/asj.2020.0133

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  • Spontaneous Improvement of Postoperative Coronal Imbalance Following Selective Thoracolumbar-Lumbar Fusion in Lenke 5C Adolescent Idiopathic Scoliosis. Reviewed

    Matsumura A, Iwamae M, Namikawa T, Kato M, Hori Y, Hidaka N, Nakamura H, Terai H

    World neurosurgery   151   e241 - e249   2021.07( ISSN:1878-8750

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    DOI: 10.1016/j.wneu.2021.04.024

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  • 【痛み-慢性痛研究の最近の話題と将来展望】治療 骨粗鬆症性椎体骨折の治療にエビデンスはあるのか? Reviewed

    星野 雅俊, 寺井 秀富, 高橋 真治

    医学のあゆみ   278 ( 1 )   88 - 93   2021.07( ISSN:0039-2359

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    痛みの克服は高齢者の日常生活動作(ADL)や生活の質(QOL)の向上に大きく寄与するため重要テーマであり、骨粗鬆症性椎体骨折(OVF)は高齢者の痛みの原因となる代表的疾患である。急性期臨床椎体骨折の治療に関する文献的考察と自験データをまとめたところ、「骨粗鬆症性椎体骨折の治療にエビデンスはあるのか?」への答えは「いいえ」であった。われわれ整形外科医が第一義的責任を持ってその治療体系の策定を行うべきであり、超高齢社会におけるその責務は大きい。(著者抄録)

  • The effect of minimally invasive lumbar decompression surgery on sagittal spinopelvic alignment in patients with lumbar spinal stenosis: a 5-year follow-up study. Reviewed

    Salimi H, Toyoda H, Yamada K, Terai H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Hori Y, Yabu A, Nakamura H

    Journal of neurosurgery. Spine   35 ( 2 )   1 - 8   2021.06( ISSN:1547-5654

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    DOI: 10.3171/2020.11.SPINE201552

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  • Expression and function of FGF9 in the hypertrophied ligamentum flavum of lumbar spinal stenosis patients. Reviewed

    Habibi H, Suzuki A, Hayashi K, Salimi H, Terai H, Hori Y, Tamai K, Orita K, Ohyama S, Yabu A, Maruf MH, Nakamura H

    The spine journal : official journal of the North American Spine Society   21 ( 6 )   1010 - 1020   2021.06( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2021.02.004

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  • Differences in surgical outcome after anterior corpectomy and reconstruction with an expandable cage with rectangular footplates between thoracolumbar and lumbar osteoporotic vertebral fracture. Reviewed

    Terai H, Takahashi S, Yasuda H, Konishi S, Maeno T, Kono H, Matsumura A, Namikawa T, Kato M, Hoshino M, Tamai K, Toyoda H, Suzuki A, Nakamura H

    North American Spine Society journal   6   100071   2021.06

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    DOI: 10.1016/j.xnsj.2021.100071

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  • 特集 ロコモティブシンドロームの現況 Ⅳ.住民コホートによる評価 8.Shiraniwaスタディ Reviewed

    大山 翔一朗, 高橋 真治, 寺井 秀富, 星野 雅俊, 中村 博亮

    整形外科   72 ( 6 )   642 - 645   2021.05( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j_seikei72_642

  • Characteristics of Elderly Patients with Deteriorating Spinal Sagittal Imbalance Reviewed

    Ohyama Shoichiro, Takahashi Shinji, Terai Hidetomi, Hoshino Masatoshi, Tsujio Tadao, Nakamura Hiroaki

    Journal of Spine Research   12 ( 5 )   759 - 765   2021.05( ISSN:18847137 ( eISSN:24351563

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    <p><b>Introduction: </b>Spinal sagittal imbalance is reported to be associated with a decline in patients' quality of life; however, the cause of its progression has not been investigated. The purpose of this study was to clarify the characteristics of elderly patients with deteriorating spinal sagittal imbalance over a 2-year period.</p><p><b>Methods: </b>A total of 321 participants (133 males and 188 females; mean age 72.9±4.9 years) from the Shiraniwa study were included in this analysis. Based on the SVA measured from whole spine radiographs, we classified the participants into the following three groups: SVA≤40 mm, 40 mm<SVA≤95 mm, and SVA>95 mm. Participants who showed disease progression from the first year to the third year were defined as the deteriorating spinal sagittal imbalance (DSI) group.</p><p>We compared the following items between DSI and non-DSI groups: the incidence of prevalent vertebral fractures, disc degeneration, and back muscle strength; locomotive syndrome (LS) stage 2; and sarcopenia. Using multiple logistic regression analysis, we investigated the predictors for DSI. Moreover, body composition measured using a bio-impedance analysis machine (BIA) was compared between the two groups.</p><p><b>Results: </b>Overall, 45 (14.0%) participants were classified into the DSI group. The prevalence of LS stage 2 was significantly higher in the DSI group than in the non-DSI group (55.6% vs. 28.0%; p<0.01). LS stage 2 was an independent predictor of DSI with an adjusted odds ratio of 2.35 (95% CI: 1.08-5.12). Regarding the body composition measured by BIA, the ratio of trunk muscle to trunk weight percentage was significantly lower in the DSI group (male: 74.1%/78.2%, p=0.02; women: 63.7%/70.9%, p<0.01).</p><p><b>Conclusions: </b>LS stage 2 was an independent predictor of deteriorating spinal sagittal imbalance over a 2-year period. Elderly patients with deteriorating spinal sagittal imbalance showed a significantly lower ratio of trunk muscle to trunk weight percentage.</p>

    DOI: 10.34371/jspineres.2021-0014

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  • 特集 ロコモティブシンドロームの現況 Ⅵ.疾患とロコモ 3.脊柱アライメントと筋量,筋力 Reviewed

    堀 悠介, 高橋 真治, 大山 翔一朗, 星野 雅俊, 寺井 秀富, 中村 博亮

    整形外科   72 ( 6 )   667 - 670   2021.05( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j_seikei72_667

  • 特集 骨粗鬆症性椎体骨折-難治例の診断・治療を中心に- 急性期骨粗鬆症性椎体骨折の診断-難治例の予測も含めて Reviewed

    寺井 秀富, 高橋 真治, 星野 雅俊, 藪 晋人, 中村 博亮

    関節外科 基礎と臨床   40 ( 5 )   482 - 488   2021.05( ISSN:02865394

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    DOI: 10.18885/jjs.0000000631

  • 特集 骨粗鬆症性椎体骨折-難治例の診断・治療を中心に- 骨粗鬆症性椎体骨折に対するBKP治療-難治例への応用とピットフォール Reviewed

    高橋 真治, 寺井 秀富, 星野 雅俊, 大山 翔一朗, 堀 悠介, 中村 博亮

    関節外科 基礎と臨床   40 ( 5 )   529 - 534   2021.05( ISSN:02865394

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    DOI: 10.18885/jjs.0000000637

  • Risk Factor for Poor Patient Satisfaction After Lumbar Spine Surgery in Elderly Patients Aged Over 80 years. Reviewed

    Hikata T, Ishii K, Matsumoto M, Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Endo K, Suzuki H, Nakano A, Watanabe K, Ohya J, Chikuda H, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Kobayashi R, Iizuka Y, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Abe T, Fujii K, Kaito T, Eguchi Y, Furuya T, Orita S, Ohtori S

    Clinical spine surgery   34 ( 4 )   E223 - E228   2021.05( ISSN:2380-0186

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    DOI: 10.1097/BSD.0000000000001101

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  • 【ロコモティブシンドロームの現況】住民コホートによる評価 Shiraniwaスタディ Reviewed

    大山 翔一朗, 高橋 真治, 寺井 秀富, 星野 雅俊, 中村 博亮

    整形外科   72 ( 6 )   642 - 645   2021.05( ISSN:0030-5901

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    <文献概要>はじめに 本邦の超高齢社会への対策上の課題として,高齢者の実数や,今後の高齢者増加率が都市部で圧倒的に高いという現状を考慮すると,都市部在住高齢者の健康実態,特に整形外科にとっては運動器の実態調査をする必要がある.そこでわれわれは2016年8月より,第三次産業に従事してきた高齢者を中心とする大都市圏ベッドタウンである奈良県生駒市において都市圏高齢者運動器コホート研究(Shiraniwaスタディ)を開始した.対象は歩行可能な65歳以上の高齢者で,縦断5年間,計6回の運動器調査に参加する意志がある方とし,自治体回覧板および院内掲示により参加を募った.初年度409名(男性164名,女性245名,平均年齢73.5歳)が参加し,現在進行形で調査中である.本稿ではShiraniwaスタディより得たロコモティブシンドローム(ロコモ)に関する知見について述べる.

  • 脊柱インバランスが進行する高齢者の特徴は? 都市圏高齢者運動器コホート研究(Shiraniwa Study)2年経過の結果より Reviewed

    大山 翔一朗, 高橋 真治, 寺井 秀富, 星野 雅俊, 辻尾 唯雄, 中村 博亮

    Journal of Spine Research   12 ( 5 )   759 - 765   2021.05( ISSN:1884-7137

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    はじめに:本研究の目的は脊柱インバランスが進行する高齢者の特徴を示すことである.対象と方法:Shiraniwa Study初年度,3年次のいずれにも参加した321名(男性133名,女性188名,平均72.9±4.9歳)を対象とした.全脊柱X線写真より計測したC7SVAより,≦40mm,40mm〜95mm,>95mmの3段階に分け,2年の経過で1段階以上増悪したものを進行群とし,その特徴を評価した.結果:14.0%(45名)が進行群に該当した.ロコモ度2該当者は進行群で有意に多く(55.6%/28.0%,p<0.01),調整オッズ比2.35(95%信頼区間:1.08〜5.12)と脊柱インバランス進行の独立した予測因子であった一方で,既存椎体骨折,椎間板変性,背筋力,サルコペニア有病率に有意差は認めなかった.また,体幹部重量に占める筋量が進行群で有意に低かった(男:74.1%/78.2%,p=0.02,女:63.7%/70.9%,p<0.01).結語:ロコモ度2は脊柱インバランス進行の予測因子であり,進行群で体幹部重量に占める筋量が有意に低かった.(著者抄録)

  • 思春期特発性側彎症に対する新たな凸型ロット回旋矯正法の手術成績(Surgical Outcomes of a New Technique Using a Convex Rod Rotation Maneuver for Adolescent Idiopathic Scoliosis) Reviewed

    Takahashi Shinji, Terai Hidetomi, Toyoda Hiromitsu, Hoshino Masatoshi, Suzuki Akinobu, Tamai Koji, Ohyama Shoichiro, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 3 )   205 - 210   2021.05

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  • 【骨粗鬆症性椎体骨折-難治例の診断・治療を中心に-】骨粗鬆症性椎体骨折に対するBKP治療 難治例への応用とピットフォール Reviewed

    高橋 真治, 寺井 秀富, 星野 雅俊, 大山 翔一朗, 堀 悠介, 中村 博亮

    関節外科   40 ( 5 )   529 - 534   2021.05( ISSN:0286-5394

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    <文献概要>Balloon kyphoplasty(BKP)は,骨粗鬆症性椎体骨折(osteoporotic vertebral fracture;OVF)に対してよく行われる手技ではあるが,BKPが適応となる骨折型にはまだまだ議論の余地がある。患者の全身状態やOVFが多発している場合など後方固定を選択しにくい状況もあるが,その場合にBKPでどこまで対応可能かは未知な部分も多い。本稿ではBKPがどういった症例に有用なのか,筆者らの過去のデータを示しながら具体例を論じている。本稿を参考にしていただき今後の診療に役立てていただきたい。

  • 【骨粗鬆症性椎体骨折-難治例の診断・治療を中心に-】急性期骨粗鬆症性椎体骨折の診断 難治例の予測も含めて Reviewed

    寺井 秀富, 高橋 真治, 星野 雅俊, 藪 晋人, 中村 博亮

    関節外科   40 ( 5 )   482 - 488   2021.05( ISSN:0286-5394

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    <文献概要>診断の目的は大きく2つであり,1つは骨粗鬆症治療に重要な形態骨折を判別すること,もう1つは骨折治療が必要な臨床骨折を判別することである。「疼痛持続・ADL(activities of daily living)低下」や単純X線で「強い椎体圧壊やクレフト」がみられた患者にはMRIを撮像し精度の高い予後予測を行うべきであり,予後不良が予見される患者には慎重な経過観察を施さなくてはならない。

  • 【運動器疼痛】運動器疼痛の臨床研究 脊柱インバランス進行予測因子 Reviewed

    大山 翔一朗, 高橋 真治, 星野 雅俊, 寺井 秀富, 辻尾 唯雄, 中村 博亮

    ペインクリニック   42 ( 別冊春 )   S139 - S147   2021.05( ISSN:0388-4171

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    脊柱インバランスは運動器疼痛のみならず、高齢者のQOLを著しく損なうことが知られているが、その原因については十分に解明されていない。われわれが実施している都市圏高齢者運動器コホート研究(Shiraniwa Study)の結果より、加齢、椎間板変性、背筋力低下、ロコモ度2はそれぞれ独立した脊柱インバランスの関連因子であることが判明した。また、ロコモ度2は2年の経過で新たに脊柱インバランスが進行することを予測する因子でもあり、脊柱インバランス進行を予防する上でのターゲットとなり得る。(著者抄録)

  • 【ロコモティブシンドロームの現況】疾患とロコモ 脊柱アライメントと筋量,筋力 Reviewed

    堀 悠介, 高橋 真治, 大山 翔一朗, 星野 雅俊, 寺井 秀富, 中村 博亮

    整形外科   72 ( 6 )   667 - 670   2021.05( ISSN:0030-5901

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    <文献概要>はじめに 超高齢社会において脊椎疾患の病的意義はますます大きい.特に脊柱矢状面アライメントの悪化は腰痛や生活の質(QOL)に大きな影響を及ぼし,高齢者の日常生活を著しく障害する.手術機器,技術の進歩により脊柱変形に対する矯正固定術が行われるようになってはいるが,高齢者では高い合併症率や高コストが報告されており,予防的治療を中心とした治療戦略への見直しが必要である.近年ではサルコペニアをはじめ,筋量減少と疾病との関係に注目が集まっている.体幹筋は脊柱の支持に不可欠な要素であり,体幹筋への介入により脊柱変形を予防できる可能性はあるが,脊柱アライメントと体幹筋量や筋力との関係は十分に解明されていない.本稿では脊柱アライメントと,特に体幹部の筋量,筋力との関係について筆者らの研究成果を最新の知見をふまえて考察する.

  • Gender-specific analysis for the association between trunk muscle mass and spinal pathologies. Reviewed

    Hori Y, Hoshino M, Inage K, Miyagi M, Takahashi S, Ohyama S, Suzuki A, Tsujio T, Terai H, Dohzono S, Sasaoka R, Toyoda H, Kato M, Matsumura A, Namikawa T, Seki M, Yamada K, Habibi H, Salimi H, Yamashita M, Yamauchi T, Furuya T, Orita S, Maki S, Shiga Y, Inoue M, Inoue G, Fujimaki H, Murata K, Kawakubo A, Kabata D, Shintani A, Ohtori S, Takaso M, Nakamura H

    Scientific reports   11 ( 1 )   7816   2021.04

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    DOI: 10.1038/s41598-021-87334-4

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  • Classification and prognostic factors of residual symptoms after minimally invasive lumbar decompression surgery using a cluster analysis: a 5-year follow-up cohort study. Reviewed

    Toyoda H, Yamada K, Terai H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Ohyama S, Hori Y, Yabu A, Salimi H, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   30 ( 4 )   918 - 927   2021.04( ISSN:0940-6719

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    DOI: 10.1007/s00586-021-06754-y

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  • Trunk Muscle Mass Measured by Bioelectrical Impedance Analysis Reflecting the Cross-Sectional Area of the Paravertebral Muscles and Back Muscle Strength: A Cross-Sectional Analysis of a Prospective Cohort Study of Elderly Population. Reviewed

    Salimi H, Ohyama S, Terai H, Hori Y, Takahashi S, Hoshino M, Yabu A, Habibi H, Kobayashi A, Tsujio T, Kotake S, Nakamura H

    Journal of clinical medicine   10 ( 6 )   1 - 10   2021.03

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    DOI: 10.3390/jcm10061187

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  • Biglycan expression and its function in human ligamentum flavum. Reviewed

    Salimi H, Suzuki A, Habibi H, Orita K, Hori Y, Yabu A, Terai H, Tamai K, Nakamura H

    Scientific reports   11 ( 1 )   4867   2021.03

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    DOI: 10.1038/s41598-021-84363-x

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  • Time Course of Physical and Mental Well-being Improvements After Cervical Surgery. Reviewed

    Tamai K, Suzuki A, Terai H, Hoshino M, Toyoda H, Takahashi S, Hori Y, Yabu A, Nakamura H

    Spine   46 ( 5 )   E303 - E309   2021.03( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000003787

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  • Relationship between number of radiological risk factors for delayed union after osteoporotic vertebral fracture and clinical outcomes. Reviewed

    Toyoda H, Hoshino M, Takahashi S, Terai H, Namikawa T, Kato M, Matsumura A, Suzuki A, Takayama K, Sasaoka R, Yasuda H, Kanematsu F, Kono H, Tsujio T, Nakamura H

    Archives of osteoporosis   16 ( 1 )   20   2021.02( ISSN:1862-3522

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    DOI: 10.1007/s11657-021-00884-y

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  • Presence of sarcopenia does not affect the clinical results of balloon kyphoplasty for acute osteoporotic vertebral fracture. Reviewed

    Ohyama S, Hoshino M, Takahashi S, Hori Y, Yasuda H, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Toyoda H, Dohzono S, Nakamura H

    Scientific reports   11 ( 1 )   122   2021.01

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    DOI: 10.1038/s41598-020-80129-z

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  • Risk factors of the poor long-term prognosis of osteoporotic vertebral fractures: A multicenter cohort study. Reviewed

    Takahashi S, Terai H, Hoshino M, Tsujio T, Suzuki A, Namikawa T, Kato M, Matsumura A, Takayama K, Toyoda H, Tamai K, Ohyama S, Hori Y, Yabu A, Nakamura H

    Journal of orthopaedic surgery (Hong Kong)   29 ( 1 )   2309499021994969   2021.01( ISSN:1022-5536

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    DOI: 10.1177/2309499021994969

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  • Reductions in the Frequency of Going Out Due to the COVID-19 Pandemic Negatively Affect Patients with Spinal Disorders

    Terai Hidetomi, Iwamae Masayoshi, Tamai Koji, Takahashi Shinji, Hori Yusuke, Ohyama Shoichiro, Yabu Akito, Hoshino Masatoshi, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 6 )   365 - 374   2021( eISSN:2432261X

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    <p>Introduction: The coronavirus disease 2019 (COVID-19) pandemic has greatly changed the lifestyles of individuals due to the need to prevent disease spread. Globally, governments have enforced various policies, including travel bans, quarantine, home confinement, and lockdowns, as safety measures. Consequently, the frequency of individuals going out has decreased. This survey aimed to assess how decreasing the frequency of going out due to the COVID-19 pandemic impacts patients with spinal disorders.</p><p>Methods: This multicenter cross-sectional questionnaire survey included patients who visited four private spine clinics for any symptoms. Participants completed questionnaires pre- and post-pandemic that assessed the following topics: frequency of leaving home, exercise habits, locomotive syndrome, and health-related quality of life (HRQOL). Patients were divided into decreased and non-decreased frequency of going out groups, according to observed changes in their frequencies of leaving home. Both groups were statistically compared using univariate and multivariate logistic regression analyses to identify factors associated with the frequency of going out.</p><p>Results: Among 855 patients, 160 (18.7%; the decreased group) reported that they went out less frequently, and 695 (81.3%; the non-decreased group) reported that they left home equally frequently post- versus pre-pandemic. Multivariate analyses showed that exercise habits significantly decreased (adjusted odds ratio (aOR) = 2.67, p = 0.004), the incidence of locomotive syndrome significantly increased (aOR = 2.86, p = 0.012), and HRQOL significantly deteriorated (aOR = 4.14, p < 0.001) in the decreased group compared to the non-decreased group.</p><p>Conclusions: Restrictions regarding leaving home due to the COVID-19 pandemic significantly decreased exercise frequency, increased the occurrence of locomotive syndrome, and were associated with deterioration of HRQOL in patients with spine disorders. It may be beneficial for spine surgeons to encourage patients with spinal disorders to leave home at a frequency similar to what they did pre-pandemic while avoiding crowded areas, despite the presence of the COVID-19 pandemic.</p>

    DOI: 10.22603/ssrr.2021-0088

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  • Percutaneous Endovascular Retrieval of Large Cement Leakage into the Right Atrium Following Cement-Augmented Pedicle Screw Instrumentation

    Takahashi Shinji, Sohgawa Etsuji, Suzuki Akinobu, Yamamoto Akira, Sasaki Ryo, Tanaka Katsuaki, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Tamai Koji, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 6 )   446 - 449   2021( eISSN:2432261X

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    DOI: 10.22603/ssrr.2021-0011

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  • Is Blood Loss Greater In Elderly Patients Under Antiplatelet Or Anticoagulant Medication For Cervical Spine Injury Surgery? A Japanese Multicenter Survey

    Uehara Masashi, Ikegami Shota, Takizawa Takashi, Oba Hiroki, Yokogawa Noriaki, Sasagawa Takeshi, Ando Kei, Nakashima Hiroaki, Segi Naoki, Funayama Toru, Eto Fumihiko, Yamaji Akihiro, Watanabe Kota, Nori Satoshi, Takeda Kazuki, Furuya Takeo, Orita Sumihisa, Nakajima Hideaki, Yamada Tomohiro, Hasegawa Tomohiko, Terashima Yoshinori, Hirota Ryosuke, Suzuki Hidenori, Imajo Yasuaki, Tonomura Hitoshi, Sakata Munehiro, Hashimoto Ko, Onoda Yoshito, Kawaguchi Kenichi, Haruta Yohei, Suzuki Nobuyuki, Kato Kenji, Uei Hiroshi, Sawada Hirokatsu, Nakanishi Kazuo, Misaki Kosuke, Terai Hidetomi, Tamai Koji, Shirasawa Eiki, Inoue Gen, Kakutani Kenichiro, Kakiuchi Yuji, Kiyasu Katsuhito, Tominaga Hiroyuki, Tokumoto Hiroto, Iizuka Yoichi, Takasawa Eiji, Akeda Koji, Takegami Norihiko, Funao Haruki, Oshima Yasushi, Kaito Takashi, Sakai Daisuke, Yoshii Toshitaka, Ohba Tetsuro, Otsuki Bungo, Seki Shoji, Miyazaki Masashi, Ishihara Masayuki, Okada Seiji, Aoki Yasuchika, Harimaya Katsumi, Murakami Hideki, Ishii Ken, Ohtori Seiji, Imagama Shiro, Kato Satoshi

    Spine Surgery and Related Research   advpub ( 0 )   2021( eISSN:2432261X

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    <p><b>Background: </b>In elderly patients with cervical spinal cord injury, comorbidities such as cardiovascular and cerebrovascular diseases are common, with frequent administration of antiplatelet/anticoagulant (APAC) drugs. Such patients may bleed easily or unexpectedly during surgery despite prior withdrawal of APAC medication. Few reports have examined the precise relationship between intraoperative blood loss and history of APAC use regarding surgery for cervical spine injury in the elderly.<b></b>The present<b></b>multicenter database survey aimed to answer the question of whether the use of APAC drugs affected the amount of intraoperative blood loss in elderly patients with cervical spinal cord trauma.</p><p><b>Methods:</b> The case histories of 1512 patients with cervical spine injury at 33 institutes were retrospectively reviewed. After excluding cases without spinal surgery or known blood loss volume, 797 patients were enrolled. Blood volume loss was the outcome of interest. We calculated propensity scores using the inverse probability of treatment weighting (IPTW) method. As an alternative sensitivity analysis, linear mixed model analyses were conducted as well.</p><p><b>Results:</b> Of the 776 patients (mean age: 75.1 ± 6.4 years) eligible for IPTW calculation, 157 (20.2%) were taking APAC medications before the injury. After weighting, mean estimated blood loss was 204 mL for non-APAC patients and 215 mL for APAC patients. APAC use in elderly patients was not significantly associated with surgical blood loss according to the IPTW method with propensity scoring or linear mixed model analyses. Thus, it appeared possible to perform surgery expecting comparable blood loss in APAC and non-APAC cases.</p><p><b>Conclusions:</b> This multicenter study revealed no significant increase in surgical blood loss in elderly patients with cervical trauma taking APAC drugs. Surgeons may be able to prioritize patient background, complications, and preexisting conditions over APAC use before injury when examining the surgical indications for cervical spine trauma in the elderly.</p>

    DOI: 10.22603/ssrr.2021-0183

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  • Clinical Characteristics and Therapeutic Outcomes of Metastatic Peritoneal Carcinomatosis in Non-Small-Cell Lung Cancer. Reviewed

    Tani T, Nakachi I, Ikemura S, Nukaga S, Ohgino K, Kuroda A, Terai H, Masuzawa K, Shinozaki T, Ishioka K, Funatsu Y, Koh H, Fukunaga K, Soejima K, Keio Lung Oncology Group (KLOG).

    Cancer management and research   13   7497 - 7503   2021

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    DOI: 10.2147/CMAR.S330103

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  • Surgical Outcomes of a New Technique Using a Convex Rod Rotation Maneuver for Adolescent Idiopathic Scoliosis

    Takahashi Shinji, Terai Hidetomi, Toyoda Hiromitsu, Hoshino Masatoshi, Suzuki Akinobu, Tamai Koji, Ohyama Shoichiro, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    Spine Surgery and Related Research   5 ( 3 )   205 - 210   2021( eISSN:2432261X

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    <p>Introduction: Because of adolescent idiopathic scoliosis (AIS), most surgeons use rod rotation on the concave side for Lenke types 1 and 2 curves. Nevertheless, the accurate placement of pedicle screws within dysplastic pedicles, especially on the concave side, is sometimes challenging. Conversely, there is a concern that apical rotation might be exacerbated after convex rod rotation maneuver (RRM) because the rod is rotated in the same direction as vertebral rotation. This study aims to demonstrate the surgical technique and outcomes of a convex RRM with direct vertebral rotation (DVR) for the correction of AIS.</p><p>Technical Note: Multilevel pedicle screws were inserted into the vertebrae. The pre-bent pure titanium rod was set on the convex side and then derotated to nearly 90°. DVR was conducted for the desired vertebrae. Another pre-bent titanium alloy rod, for placement on the concave side, was contoured the same as the rod on the convex side. Using a reduction tube that allowed easier capture of the rod, the rod was connected to the concave side screws. DVR was again conducted for the desired vertebrae. Among the 59 patients, the correction rate of the main thoracic curve in Lenke types 1 and 2 AIS was 75.1% and 65.0%, respectively. The absolute value of the change in apical vertebral rotation between pre- and post-operative computed tomography (CT) scans in Lenke types 1 and 2 curves was 4.8° and 4.2°, respectively.</p><p>Conclusions: The convex RRM improved vertebral rotation in Lenke types 1 and 2 AIS. This procedure should be regarded as one of the surgical options for AIS, especially in patients with a narrow pedicle width on the concave side.</p>

    DOI: 10.22603/ssrr.2020-0185

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  • 特集 脊椎骨粗鬆症性椎体骨折に対する治療戦略-薬物療法を中心にUP TO DATE 骨粗鬆症性椎体骨折の保存療法の限界について-前向き多施設研究結果を踏まえて Reviewed

    寺井 秀富, 高橋 真治, 星野 雅俊, 藪 晋人, 中村 博亮

    脊椎脊髄ジャーナル   33 ( 12 )   1052 - 1057   2020.12( ISSN:09144412

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    DOI: 10.11477/mf.5002201543

  • 【脊椎骨粗鬆症性椎体骨折に対する治療戦略-薬物療法を中心にUP TO DATE】骨粗鬆症性椎体骨折の保存療法の限界について 前向き多施設研究結果を踏まえて Reviewed

    寺井 秀富, 高橋 真治, 星野 雅俊, 藪 晋人, 中村 博亮

    脊椎脊髄ジャーナル   33 ( 12 )   1052 - 1057   2020.12( ISSN:0914-4412

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    <文献概要>はじめに 人生100年時代といわれる超長寿社会において,疫学的に医療の重要課題は"老化"といわれている.骨粗鬆症は老化に典型的な伴う疾患であり,人類に与える影響は各種がん以上とされる.基礎的臨床的集学的な研究が進み,骨粗鬆症が治療可能な時代となった理由のうち最も中心的な役割を担うのが薬物療法である.一方で,われわれ脊椎外科医が最前線に立って治療にあたるべき骨粗鬆症性椎体骨折(osteoporotic vertebral fracture:OVF)の治療成績は改善されているのであろうか.本稿では,われわれが15年以上にわたって注力してきた臨床OVFのデータとともに現在進行形の研究を紹介し,OVF研究の問題点と今後の展望を私見ながら提案したい.

  • The short-term outcomes of minimally invasive decompression surgery in patients with lumbar ossification or calcification of the ligamentum flavum. Reviewed

    Tamai K, Kaneda K, Iwamae M, Terai H, Katsuda H, Shimada N, Nakamura H

    Journal of neurosurgery. Spine   34 ( 2 )   1 - 8   2020.11( ISSN:1547-5654

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    DOI: 10.3171/2020.6.SPINE20946

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  • Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: A multicenter retrospective study. Reviewed

    Ishii M, Terai H, Kabata H, Masaki K, Chubachi S, Tateno H, Nakamura M, Nishio K, Koh H, Watanabe R, Ueda S, Terashima T, Suzuki Y, Yagi K, Miyao N, Minematsu N, Inoue T, Nakachi I, Namkoong H, Okamori S, Ikemura S, Kamata H, Yasuda H, Kawada I, Hasegawa N, Fukunaga K, Keio COVID-19 Research Consortium (K-CORC) and the Keio Donner Project Team.

    The Journal of infection   81 ( 5 )   e3 - e5   2020.11( ISSN:0163-4453

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    DOI: 10.1016/j.jinf.2020.08.052

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  • Simultaneous Opposition Tendon Transfer with Median Nerve Decompression for Severe Bilateral Carpal Tunnel Syndrome in Adolescents with Hunter Syndrome: A Case Report. Reviewed

    Uemura T, Okada M, Terai H, Yokoi T, Onode E, Shintani K, Konishi S, Nakamura H

    Plastic and reconstructive surgery. Global open   8 ( 11 )   e3251   2020.11

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    DOI: 10.1097/GOX.0000000000003251

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  • The Severity of Cervical Disc Degeneration Does Not Impact 2-year Postoperative Outcomes in Patients With Cervical Spondylotic Myelopathy Who Underwent Laminoplasty. Reviewed

    Habibi H, Suzuki A, Tamai K, Ohyama S, Hori Y, Yabu A, Terai H, Hoshino M, Toyoda H, Takahashi S, Ahmadi SA, Nakamura H

    Spine   45 ( 18 )   E1142 - E1149   2020.09( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000003528

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  • Short- versus long-segment posterior spinal fusion with vertebroplasty for osteoporotic vertebral collapse with neurological impairment in thoracolumbar spine: a multicenter study. Reviewed

    Ishikawa Y, Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Izumi T, Hirano T, Endo N, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    BMC musculoskeletal disorders   21 ( 1 )   513   2020.08

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    DOI: 10.1186/s12891-020-03539-0

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  • Residual numbness of the upper extremity after cervical surgery in patients with cervical spondylotic myelopathy. Reviewed

    Iwamae M, Suzuki A, Tamai K, Terai H, Hoshino M, Toyoda H, Takahashi S, Ohyama S, Hori Y, Yabu A, Nakamura H

    Journal of neurosurgery. Spine   33 ( 6 )   1 - 8   2020.07( ISSN:1547-5654

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    DOI: 10.3171/2020.4.SPINE191566

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  • Effect of bisphosphonates or teriparatide on mechanical complications after posterior instrumented fusion for osteoporotic vertebral fracture: a multi-center retrospective study. Reviewed

    Kawabata A, Yoshii T, Hirai T, Ushio S, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    BMC musculoskeletal disorders   21 ( 1 )   420   2020.07

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    DOI: 10.1186/s12891-020-03452-6

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  • The factors related to the poor ADL in the patients with osteoporotic vertebral fracture after instrumentation surgery. Reviewed

    Murata K, Matsuoka Y, Nishimura H, Endo K, Suzuki H, Takamatsu T, Sawaji Y, Aihara T, Kusakabe T, Maekawa A, Yamamoto K, Watanabe K, Kaito T, Terai H, Tamai K, Tagami A, Yoshii T, Harimaya K, Kawaguchi K, Kimura A, Inoue G, Nakano A, Sakai D, Hiyama A, Ikegami S, Ohtori S, Furuya T, Orita S, Imagama S, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Uei H, Ajiro Y, Takahata M, Endo H, Abe T, Nakanishi K, Watanabe K, Okada E, Hosogane N, Funao H, Isogai N, Ishii K

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   29 ( 7 )   1597 - 1605   2020.07( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-06092-0

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  • 神経障害を伴う下位腰椎の骨粗鬆症性椎体骨折に対する脊椎固定術の手術転帰(The Surgical Outcomes of Spinal Fusion for Osteoporotic Vertebral Fractures in the Lower Lumbar Spine with a Neurological Deficit) Reviewed

    Isogai Norihiro, Hosogane Naobumi, Funao Haruki, Nojiri Kenya, Suzuki Satoshi, Okada Eijiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Shuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   4 ( 3 )   199 - 207   2020.07

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    神経障害を伴う骨粗鬆症性椎体骨折患者403例を対象に、脊椎固定術を施行して、下位腰椎椎体骨折患者と胸腰椎移行部の椎体骨折患者における臨床的および放射線学的転帰を比較した。患者を、骨折部位に応じて下位腰椎(L3〜5)群76例(男性17例、女性59例、平均73.2±8.0歳)と腰椎移行部(T10〜L2)群327例(男性72例、女性255例、平均74.0±7.8歳)の2群に分類した。骨密度は下位腰椎群(0.59±0.21g/cm2)の方が胸腰椎移行部群(0.65±0.21g/cm2)より有意に低かった。年齢、性別、骨密度をマッチングし、下位腰椎群の患者1人に対して胸腰椎移行部群の患者2人を割り付け、L群73例とT群146例の2群に再分類した。手術時間および術中出血量に有意な群間差はなかった。融合セグメント数はT群(4.2±2.0)の方がL群(3.4±2.2)より有意に多かった(P<0.01)。内固定の機械的破綻率(mechanical failure)はL群(64%)の方がT群(39%)より有意に高かった(P<0.001)。周術期合併症および修正手術の発生率に有意な群間差はなく、臨床的および放射線学的転帰にも有意な群間差はなかった。

  • 「神経障害を伴う骨粗鬆症性椎体骨折に対する外科的治療 日本で行われた全国多施設研究」に関する編集者への回答(Reply to the Editor: Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit: A Nationwide Multicenter Study in Japan) Reviewed

    Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Funao Haruki, Okada Eijiro, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshio, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   4 ( 3 )   292 - 293   2020.07

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  • Facet joint opening on preoperative computed tomography is risk factor for revision surgery after less invasive decompression procedure for lumbar spinal stenosis Reviewed

    Yamada Kentaro, Toyoda Hiromitsu, Tamai Koji, Takahashi Shinji, Suzuki Akinobu, Hoshino Masatoshi, Terai Hidetomi, Nakamura Hiroaki

    Journal of Spine Research   11 ( 6 )   936 - 941   2020.06( ISSN:18847137 ( eISSN:24351563

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    <p><b>Purpose: </b>There is no consensus of regarding the indication of surgical treatment of the less invasive decompression procedure for lumbar spinal stenosis (LSS). Although facet joint opening (FO) on preoperative computed tomography (CT) images has been reported as a parameter indicating segmental instability, there is no report on how FO affects on postoperative outcomes. The purpose of this study was to investigate risk factors for revision surgery after less invasive decompression surgery for LSS including FO by a minimum-5-year postoperative survey.</p><p><b>Materials and Methods: </b>A total of 244 patients who underwent microscopic or microendoscopic decompression surgery for LSS and followed for ≥5 years were included in this study. We investigated revision lumbar surgeries at the same levels or other lumbar levels based on medical records. Revision surgeries due to postoperative hematoma or infection were excluded. FO was defined as a ≥2 mm opening on preoperative axial CT images at each lumbar intervertebral level. We evaluated the FO at index decompression levels and sum of FO-positive levels from L1-2 to L5-S. Risk factors for further surgeries were investigated among demographics, preoperative symptoms, and radiological parameters other than FO using univariate and cox proportional hazard regression analysis.</p><p><b>Results: </b>There was 26 reoperations (10.7%) at a mean of 3.9 years after primary surgeries. FO at index decompression levels was significantly more frequent in patients with than without revision surgeries (69 and 39%, respectively, p=0.003). The sum of FO-positive levels among lumbar segments was significantly higher in patients with than without revision surgeries (2.0 and 1.2 levels, respectively, p=0.001). The cox proportional hazard regression analysis indicated that the sum of FO-positive levels among lumbar segments was one of the risk factors for revision surgery (p=0.003, adjusted hazard ratio: 1.47).</p><p><b>Conclusions: </b>The FO of index decompression levels and sum of FO were associated with the need for further lumbar surgeries after less invasive surgery. FO might indicate not only segmental instability but also predictive parameter for progression of degenerative change.</p>

    DOI: 10.34371/jspineres.2020-0512

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  • CTにおけるfacet joint openingは腰椎変性疾患に対する低侵襲除圧術の再手術の危険因子である Reviewed

    山田 賢太郎, 豊田 宏光, 玉井 孝司, 高橋 真治, 鈴木 亨暢, 星野 雅俊, 寺井 秀富, 中村 博亮

    Journal of Spine Research   11 ( 6 )   936 - 941   2020.06( ISSN:1884-7137

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    CTにおけるfacet joint opening(FO)は不安定性の指標になるとの報告がある一方で,腰椎変性疾患に対して低侵襲除圧術の限界について一定した見解がない.本研究は低侵襲除圧術で手術加療を行い最低5年の経過観察をしえた244例の再手術についてFOを含めて危険因子解析を行った.その結果,除圧椎間のFOのみならず,腰椎全体でFOをきたす椎間が多いことも再手術の危険因子であることが示された.(著者抄録)

  • Improvement in Patient Mental Well-being After Surgery for Cervical Spondylotic Myelopathy. Reviewed

    Tamai K, Suzuki A, Terai H, Hoshino M, Toyoda H, Takahashi S, Ohyama S, Hori Y, Yabu A, Nakamura H

    Spine   45 ( 10 )   E568 - E575   2020.05( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000003337

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  • One case of C2 aneurysmal bone cyst treated minimally invasive using endoscope and navigation Reviewed

    KAWAI Hideyuki

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   63 ( 3 )   461 - 462   2020.05( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2020.461

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  • 内視鏡とナビゲーションを併用し低侵襲に治療しえたC2動脈瘤様骨嚢腫の1例 Reviewed

    河合 秀幸, 鈴木 亨暢, 寺井 秀富, 星野 雅俊, 豊田 宏光, 中村 博亮

    中部日本整形外科災害外科学会雑誌   63 ( 3 )   461 - 462   2020.05( ISSN:0008-9443

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    17歳男。頸部痛を主訴とした。多発性線維性骨異形成症による併存症、L2・L3の動脈瘤様骨嚢腫に対してハイドロキシアパタイト(HA)を用いた椎体形成術の既往があり、頸椎単純CTでは後頭骨・頭蓋底および各頸椎椎体のすりガラス状陰影、C2椎体に骨溶解像と後壁の菲薄化、病的骨折を疑わせる後壁の一部途絶を認めた。線維性骨異形成症に伴うC2動脈瘤様骨嚢腫による切迫骨折と診断して内視鏡と術中CT navigation下に頸椎前方アプローチでHAを用いたC2椎体形成術を選択し、最小侵襲で安全に椎体形成術を行うことができた。病理診断は線維性骨異形成症に伴う動脈瘤性骨嚢腫で、術後1週の単純CTではC2内にHAが充填されており、脱出や隣接椎体に明らかな骨折などは認めなかった。

  • Scalable implementation of a superconducting nanowire single-photon detector array with a superconducting digital signal processor. Reviewed

    Yabuno M, Miyajima S, Miki S, Terai H

    Optics express   28 ( 8 )   12047 - 12057   2020.04

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    DOI: 10.1364/OE.388302

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  • Surgical Management of Spinal Disorders in People with Mucopolysaccharidoses. Reviewed

    Terai H, Nakamura H

    International journal of molecular sciences   21 ( 3 )   2020.02

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    DOI: 10.3390/ijms21031171

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  • Surgical Management of Spinal Disorders in People with Mucopolysaccharidoses. Reviewed

    Terai H, Nakamura H

    International journal of molecular sciences   21 ( 3 )   2020.02( ISSN:16616596

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    DOI: 10.3390/ijms21031171

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  • Surgical treatment for spinal disorders with osteoporotic vertebral fractures Reviewed

    63 ( 2 )   187 - 194   2020.02( ISSN:03874095

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    DOI: 10.18888/se.0000001183

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  • Clinical Impact of Cervical Imbalance on Surgical Outcomes of Laminoplasty: A Propensity Score-Matching Analysis. Reviewed

    Tamai K, Suzuki A, Yabu A, Terai H, Hoshino M, Toyoda H, Takahashi S, Ohyama S, Hori Y, Nakamura H

    Clinical spine surgery   33 ( 1 )   E1 - E7   2020.02( ISSN:2380-0186

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    DOI: 10.1097/BSD.0000000000000849

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  • 【骨粗鬆症性椎体骨折治療の最新知見】骨粗鬆症性椎体骨折による脊椎障害に対する手術治療 Reviewed

    寺井 秀富, 中村 博亮

    整形・災害外科   63 ( 2 )   187 - 194   2020.02( ISSN:0387-4095

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    <文献概要>骨粗鬆症性椎体骨折は背部痛だけでなく,神経圧排や脊柱変形など様々な脊椎障害の原因となる。骨粗鬆症性椎体骨折に対する治療は薬物治療を含む保存治療から外科的治療まで多岐にわたり現在もエビデンスの構築が進んでいる。椎体形成術に対するエビデンスは本邦を中心として蓄積が進んでいるが,椎体形成術以外の外科的治療に関しては病態のバリエーションが多く,一定の見解が得られていないのが現状である。椎体形成術以外の外科的手術方法の選択には病態の把握が重要であり,病態に即してin situ固定,椎体形成術+後方固定,前方固定,骨切り術を含めた変形矯正などが選択され,時にはそれらを同時に行うこともある。前方固定術では局所後彎の矯正は可能であるが,短い後方固定では脊柱アライメント矯正は得られないが満足な除痛効果とADLの改善は得られることから,病態に即した術式選択が重要であるといえる。

  • Delayed-onset pneumothorax after posterior spinal fusion for idiopathic scoliosis: Report of two cases Reviewed

    Terai H.

    Indian Spine Journal   3 ( 1 )   110 - 113   2020.01( ISSN:25895079

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    DOI: 10.4103/isj.isj_16_19

  • The Surgical Outcomes of Spinal Fusion for Osteoporotic Vertebral Fractures in the Lower Lumbar Spine with a Neurological Deficit Reviewed

    Isogai Norihiro, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Hosogane Naobumi, Nishimura Hirosuke, Tagami Atsushi, Yamada Shuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Funao Haruki, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Nojiri Kenya, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Suzuki Satoshi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Okada Eijiro, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken, Ueda Seiji, Hikata Tomohiro, Shiono Yuta

    一般社団法人 日本脊椎脊髄病学会 Spine Surgery and Related Research   2020

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    <p><b>Introduction</b>: Osteoporotic vertebral fracture (OVF) is the most common osteoporotic fracture, and some patients require surgical intervention to improve their impaired activities of daily living with neurological deficits. However, many previous reports have focused on OVF around the thoracolumbar junction, and the surgical outcomes of lumbar OVF have not been thoroughly discussed. We aimed to investigate the surgical outcomes for lumbar OVF with a neurological deficit.</p><p><b>Methods: </b>Patients who underwent fusion surgery for thoracolumbar OVF with a neurological deficit were enrolled at 28 institutions. Clinical information, comorbidities, perioperative complications, Japanese Orthopaedic Association scores, visual analog scale scores, and radiographic parameters were compared between patients with lower lumbar fracture (L3-5) and those with thoracolumbar junction fracture (T10-L2). Each patient with lower lumbar fracture (L group) was matched with to patients with thoracolumbar junction fracture (T group).</p><p><b>Results: </b>A total 403 patients (89 males and 314 females, mean age: 73.8 ± 7.8 years, mean follow-up: 3.9 ± 1.7 years) were included in this study. Lower lumbar OVF was frequently found in patients with lower bone mineral density. After matching, mechanical failure was more frequent in the L group (L group: 64%, T group: 39%; p < 0.001). There was no difference between groups in the clinical and radiographical outcomes, although the rates of complication and revision surgery were still high in both groups.</p><p><b>Conclusions: </b>The surgical intervention for OVF is effective in patients with myelopathy or radiculopathy regardless of the surgical level, although further study is required to improve clinical and radiographical outcomes.</p>

    DOI: 10.22603/ssrr.2019-0079

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  • Reply to the Editor: Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit-A Nationwide Multicenter Study in Japan

    Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Funao Haruki, Okada Eijiro, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshio, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   4 ( 3 )   292 - 293   2020( eISSN:2432261X

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    DOI: 10.22603/ssrr.2020-0033

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  • Cognitive Modeling of Automation Adaptation in a Time Critical Task. Reviewed

    Morita J, Miwa K, Maehigashi A, Terai H, Kojima K, Ritter FE

    Frontiers in psychology   11   2149   2020

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    DOI: 10.3389/fpsyg.2020.02149

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  • Analysis of clinical outcomes in elderly patients with impaired swallowing function. Reviewed

    Sunata K, Terai H, Seki H, Mitsuhashi M, Kagoshima Y, Nakayama S, Wakabayashi K, Muraoka K, Suzuki Y, Suzuki Y

    PloS one   15 ( 9 )   e0239440   2020

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    DOI: 10.1371/journal.pone.0239440

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  • The Surgical Outcomes of Spinal Fusion for Osteoporotic Vertebral Fractures in the Lower Lumbar Spine with a Neurological Deficit

    Isogai Norihiro, Hosogane Naobumi, Funao Haruki, Nojiri Kenya, Suzuki Satoshi, Okada Eijiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Shuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   4 ( 3 )   199 - 207   2020( eISSN:2432261X

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    <p>Introduction: Osteoporotic vertebral fracture (OVF) is the most common osteoporotic fracture, and some patients require surgical intervention to improve their impaired activities of daily living with neurological deficits. However, many previous reports have focused on OVF around the thoracolumbar junction, and the surgical outcomes of lumbar OVF have not been thoroughly discussed. We aimed to investigate the surgical outcomes for lumbar OVF with a neurological deficit.</p><p>Methods: Patients who underwent fusion surgery for thoracolumbar OVF with a neurological deficit were enrolled at 28 institutions. Clinical information, comorbidities, perioperative complications, Japanese Orthopaedic Association scores, visual analog scale scores, and radiographic parameters were compared between patients with lower lumbar fracture (L3-5) and those with thoracolumbar junction fracture (T10-L2). Each patient with lower lumbar fracture (L group) was matched with to patients with thoracolumbar junction fracture (T group).</p><p>Results: A total 403 patients (89 males and 314 females, mean age: 73.8 ± 7.8 years, mean follow-up: 3.9 ± 1.7 years) were included in this study. Lower lumbar OVF was frequently found in patients with lower bone mineral density. After matching, mechanical failure was more frequent in the L group (L group: 64%, T group: 39%; p < 0.001). There was no difference between groups in the clinical and radiographical outcomes, although the rates of complication and revision surgery were still high in both groups.</p><p>Conclusions: The surgical intervention for OVF is effective in patients with myelopathy or radiculopathy regardless of the surgical level, although further study is required to improve clinical and radiographical outcomes.</p><p>Level of evidence: Level III</p>

    DOI: 10.22603/ssrr.2019-0079

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  • Characteristic radiological findings for revision surgery after balloon kyphoplasty Reviewed

    Takahashi Shinji, Hoshino Masatoshi, Yasuda Hiroyuki, Hori Yusuke, Ohyama Shoichiro, Terai Hidetomi, Hayashi Kazunori, Tsujio Tadao, Kono Hiroshi, Suzuki Akinobu, Tamai Koji, Toyoda Hiromitsu, Dohzono Sho, Sasaoka Ryuichi, Kanematsu Fumiaki, Terakawa Masaki, Nakamura Hiroaki

    SCIENTIFIC REPORTS   9 ( 1 )   18513   2019.12( ISSN:2045-2322

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    DOI: 10.1038/s41598-019-55054-5

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  • Characteristic radiological findings for revision surgery after balloon kyphoplasty. Reviewed

    Takahashi S, Hoshino M, Yasuda H, Hori Y, Ohyama S, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Toyoda H, Dohzono S, Sasaoka R, Kanematsu F, Terakawa M, Nakamura H

    Scientific reports   9 ( 1 )   18513   2019.12

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    DOI: 10.1038/s41598-019-55054-5

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  • Improvement in Patient Mental Well-being After Surgery for Cervical Spondylotic Myelopathy. Reviewed

    Tamai K, Suzuki A, Terai H, Hoshino M, Toyoda H, Takahashi S, Ohyama S, Hori Y, Yabu A, Nakamura H

    Spine   2019.11( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000003337

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  • Impact of Sarcopenia on Clinical Outcomes of Minimally Invasive Lumbar Decompression Surgery. Reviewed

    Toyoda H, Hoshino M, Ohyama S, Terai H, Suzuki A, Yamada K, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    Scientific reports   9 ( 1 )   16619   2019.11

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    DOI: 10.1038/s41598-019-53053-0

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  • Surgical outcomes of spinal fusion for osteoporotic vertebral fracture in the thoracolumbar spine: Comprehensive evaluations of 5 typical surgical fusion techniques. Reviewed

    Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Hirano T, Endo N, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 6 )   1020 - 1026   2019.11( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2019.07.018

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  • Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study. Reviewed

    Sakai Y, Kaito T, Takenaka S, Yamashita T, Makino T, Hosogane N, Nojiri K, Suzuki S, Okada E, Watanabe K, Funao H, Isogai N, Ueda S, Hikata T, Shiono Y, Watanabe K, Katsumi K, Fujiwara H, Nagamoto Y, Terai H, Tamai K, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Ohtori S, Orita S, Furuya T, Yoshii T, Ushio S, Inoue G, Miyagi M, Saito W, Imagama S, Ando K, Sakai D, Nukaga T, Kiyasu K, Kimura A, Inoue H, Nakano A, Harimaya K, Doi T, Kawaguchi K, Yokoyama N, Oishi H, Ikegami S, Futatsugi T, Shimizu M, Kakutani K, Yurube T, Oshima M, Uei H, Aoki Y, Takahata M, Iwata A, Seki S, Murakami H, Yoshioka K, Endo H, Hongo M, Nakanishi K, Abe T, Tsukanishi T, Ishii K

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 6 )   985 - 990   2019.11( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2019.08.015

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  • Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study(和訳中) Reviewed

    Sakai Yusuke, Kaito Takashi, Takenaka Shota, Yamashita Tomoya, Makino Takahiro, Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Okada Eijiro, Watanabe Kota, Funao Haruki, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kei, Katsumi Keiichi, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Shuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Doi Toshio, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Ikegami Shota, Futatsugi Toshimasa, Shimizu Masayuki, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    (公社)日本整形外科学会 Journal of Orthopaedic Science   24 ( 6 )   985 - 990   2019.11( ISSN:0949-2658

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  • Surgical outcomes of spinal fusion for osteoporotic vertebral fracture in the thoracolumbar spine: Comprehensive evaluations of 5 typical surgical fusion techniques(和訳中) Reviewed

    Watanabe Kei, Katsumi Keiichi, Ohashi Masayuki, Shibuya Yohei, Hirano Toru, Endo Naoto, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Terai Hidetomi, Tamai Koji, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Yoshii Toshitaka, Ushio Shuta, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Nakano Atsushi, Sakai Daisuke, Nukaga Tadashi, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Ohtori Seiji, Furuya Takeo, Orita Sumihisa, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Kiyasu Katsuhito, Murakami Hideki, Yoshioka Katsuhito, Seki Shoji, Hongo Michio, Kakutani Kenichiro, Yurube Takashi, Aoki Yasuchika, Oshima Masashi, Takahata Masahiko, Iwata Akira, Endo Hirooki, Abe Tetsuya, Tsukanishi Toshinori, Nakanishi Kazuyoshi, Watanabe Kota, Hikata Tomohiro, Suzuki Satoshi, Isogai Norihiro, Okada Eijiro, Funao Haruki, Ueda Seiji, Shiono Yuta, Nojiri Kenya, Hosogane Naobumi, Ishii Ken

    (公社)日本整形外科学会 Journal of Orthopaedic Science   24 ( 6 )   1020 - 1026   2019.11( ISSN:0949-2658

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  • General Anesthesia Management for Adult Mucopolysaccharidosis Patients Undergoing Major Spine Surgery Reviewed

    Tsuchiya Masahiko, Terai Hidetomi, Mizutani Koh, Funai Yusuke, Tanaka Katsuaki, Yamada Tokuhiro, Mori Takashi, Nishikawa Kiyonobu

    MEDICAL PRINCIPLES AND PRACTICE   28 ( 6 )   581 - 585   2019.11( ISSN:1011-7571

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    DOI: 10.1159/000503051

  • Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study. Reviewed

    Sakai Y, Kaito T, Takenaka S, Yamashita T, Makino T, Hosogane N, Nojiri K, Suzuki S, Okada E, Watanabe K, Funao H, Isogai N, Ueda S, Hikata T, Shiono Y, Watanabe K, Katsumi K, Fujiwara H, Nagamoto Y, Terai H, Tamai K, Matsuoka Y, Suzuki H, Nishimura H, Tagami A, Yamada S, Adachi S, Ohtori S, Orita S, Furuya T, Yoshii T, Ushio S, Inoue G, Miyagi M, Saito W, Imagama S, Ando K, Sakai D, Nukaga T, Kiyasu K, Kimura A, Inoue H, Nakano A, Harimaya K, Doi T, Kawaguchi K, Yokoyama N, Oishi H, Ikegami S, Futatsugi T, Shimizu M, Kakutani K, Yurube T, Oshima M, Uei H, Aoki Y, Takahata M, Iwata A, Seki S, Murakami H, Yoshioka K, Endo H, Hongo M, Nakanishi K, Abe T, Tsukanishi T, Ishii K

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 6 )   985 - 990   2019.11( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2019.08.015

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  • A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients. Reviewed

    Tani T, Naoki K, Yasuda H, Arai D, Ishioka K, Ohgino K, Yoda S, Nakayama S, Satomi R, Terai H, Ikemura S, Sato T, Soejima K

    Cancer chemotherapy and pharmacology   84 ( 5 )   1065 - 1071   2019.11( ISSN:0344-5704

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    DOI: 10.1007/s00280-019-03934-y

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  • Surgical outcomes of spinal fusion for osteoporotic vertebral fracture in the thoracolumbar spine: Comprehensive evaluations of 5 typical surgical fusion techniques. Reviewed

    Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Hirano T, Endo N, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 6 )   1020 - 1026   2019.11( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2019.07.018

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  • 胸腰椎の骨粗鬆症性椎体骨折に対する脊椎固定術の成績 5種類の定型手技の包括的評価(Surgical outcomes of spinal fusion for osteoporotic vertebral fracture in the thoracolumbar spine: Comprehensive evaluations of 5 typical surgical fusion techniques) Reviewed

    Watanabe Kei, Katsumi Keiichi, Ohashi Masayuki, Shibuya Yohei, Hirano Toru, Endo Naoto, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Terai Hidetomi, Tamai Koji, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Yoshii Toshitaka, Ushio Shuta, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Nakano Atsushi, Sakai Daisuke, Nukaga Tadashi, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Ohtori Seiji, Furuya Takeo, Orita Sumihisa, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Kiyasu Katsuhito, Murakami Hideki, Yoshioka Katsuhito, Seki Shoji, Hongo Michio, Kakutani Kenichiro, Yurube Takashi, Aoki Yasuchika, Oshima Masashi, Takahata Masahiko, Iwata Akira, Endo Hirooki, Abe Tetsuya, Tsukanishi Toshinori, Nakanishi Kazuyoshi, Watanabe Kota, Hikata Tomohiro, Suzuki Satoshi, Isogai Norihiro, Okada Eijiro, Funao Haruki, Ueda Seiji, Shiono Yuta, Nojiri Kenya, Hosogane Naobumi, Ishii Ken

    Journal of Orthopaedic Science   24 ( 6 )   1020 - 1026   2019.11( ISSN:0949-2658

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    胸腰椎の骨粗鬆症性椎体骨折(OVF)に対する脊椎固定術の術後成績について検討した。脊椎固定術を施行され、2年以上の経過観察が可能であったOVF症例315例を対象とし、術式に基づいて前方固定群(ASF群)19例(男性6例、女性13例、中央値70歳)、前方/後方併用固定群(APSF群)27例(男性5例、女性22例、中央値72歳)、後方固定群(PSF群)40例(男性11例、女性29例、中央値75歳)、3-カラム骨切り+後方固定群(3CO群)92例(男性4例、女性88例、中央値72歳)、椎体形成+後方固定群(VP+PSF群)137例(男性42例、女性95例、中央値77歳)に分類した。平均手術時間はAPSF群が最も長く、術中出血量は3CO群の方がPSF群、VP+PSF群より多かった。周術期合併症の発症率に有意な群間差はなかった。術後の局所後彎角はPSF群を除く各群で有意に改善しており、改善度はAPSF群と3CO群が他の手技群と比較して良好であった。器具破損は59例(18.7%)にみられ、有意な群間差はみられなかった。また、腰痛と下肢痛のVASスコアは各群とも術後に有意に改善し、有意な群間差はなかった。JOAスコアも各群で有意に改善したが、ASF群の回復率は他の手技群と比較して低値を示していた。今回検討した5種類の脊椎固定術はいずれも神経学的・機能的成績の改善に優れていると考えられた。

  • 神経障害を伴う骨粗鬆症性椎体圧潰に対する脊椎固定術後の合併症 日本脊椎外科学会多施設研究(Complications after spinal fixation surgery for osteoporotic vertebral collapse with neurological deficits: Japan Association of Spine Surgeons with ambition multicenter study) Reviewed

    Sakai Yusuke, Kaito Takashi, Takenaka Shota, Yamashita Tomoya, Makino Takahiro, Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Okada Eijiro, Watanabe Kota, Funao Haruki, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kei, Katsumi Keiichi, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Shuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Doi Toshio, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Ikegami Shota, Futatsugi Toshimasa, Shimizu Masayuki, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Journal of Orthopaedic Science   24 ( 6 )   985 - 990   2019.11( ISSN:0949-2658

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    神経障害を伴う骨粗鬆症性椎体圧潰(OVC)に対する脊椎固定術後の合併症の発症率とリスク因子について検討した。OVC患者403例(男性89例、女性314例、平均73.8±7.8歳)を対象とする後ろ向き多施設共同研究を実施した。年齢、性別、BMI等の患者データを収集するとともに、術後6週以内に生じた合併症を調査した。その結果、術中合併症を15例(3.7%)に認め、硬膜断裂、神経障害、大量出血、静脈損傷などがみられた。6週以内の術後合併症の発症は57例(14.1%)であり、せん妄、硬膜外血腫、手術部位感染症、深部静脈血栓症、肺炎、尿路感染症、脳梗塞、心不全がみられた。このうち、せん妄が23例(5.7%)と最も多く、死亡例はなかった。脊椎固定に際して5種類の手技が用いられていたが、合併症の発症率に差はみられなかった。単変量解析では術後合併症の発症は高齢者、男性、肝疾患、パーキンソン病に多く、BMI、喫煙歴、ステロイドの服用、疼痛VAS、JOAスコア、手術手技、手術時間、予測出血量と合併症発症との関連はみられなかった。単変量解析では、術後合併症発症の独立リスク因子として、年齢、肝疾患、パーキンソン病が抽出された。

  • Fibroblast Growth Factor 9 Is Upregulated Upon Intervertebral Mechanical Stress-Induced Ligamentum Flavum Hypertrophy in a Rabbit Model Reviewed

    Hayashi Kazunori, Suzuki Akinobu, Terai Hidetomi, Ahmadi Sayed Abdullah, Rahmani Mohammad Suhrab, Maruf Mohammad Hasib, Habibi Hasibullah, Hori Yusuke, Yamada Kentaro, Hoshino Masatoshi, Toyoda Hiromitsu, Takahashi Shinji, Tamai Koji, Ohyama Shoichiro, Imai Yuuki, Nakamura Hiroaki

    SPINE   44 ( 20 )   E1172 - E1180   2019.10( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000003089

  • Fibroblast Growth Factor 9 Is Upregulated Upon Intervertebral Mechanical Stress-Induced Ligamentum Flavum Hypertrophy in a Rabbit Model. Reviewed

    Hayashi K, Suzuki A, Terai H, Ahmadi SA, Rahmani MS, Maruf MH, Habibi H, Hori Y, Yamada K, Hoshino M, Toyoda H, Takahashi S, Tamai K, Ohyama S, Imai Y, Nakamura H

    Spine   44 ( 20 )   E1172 - E1180   2019.10( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000003089

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  • Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit: A Nationwide Multicenter Study in Japan(和訳中) Reviewed

    Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Funao Haruki, Okada Eijiro, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshio, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    (一社)日本脊椎脊髄病学会 Spine Surgery and Related Research   3 ( 4 )   361 - 367   2019.10

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  • Increased advanced glycation end products in hypertrophied ligamentum flavum of diabetes mellitus patients. Reviewed

    Maruf MH, Suzuki A, Hayashi K, Habibi H, Salimi H, Terai H, Tamai K, Hoshino M, Toyoda H, Yamada K, Takahashi S, Ohyama S, Hori Y, Nakamura H

    The spine journal : official journal of the North American Spine Society   19 ( 10 )   1739 - 1745   2019.10( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2019.06.001

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  • 神経障害を伴う骨粗鬆症性椎体骨折に対する外科的治療 日本における全国多施設共同研究(Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit: A Nationwide Multicenter Study in Japan) Reviewed

    Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Funao Haruki, Okada Eijiro, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshio, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   3 ( 4 )   361 - 367   2019.10

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    骨粗鬆症性椎体圧迫骨折(OVF)偽関節に対する外科的治療のアウトカムについて検討した。後ろ向き多施設研究を実施し、OVF後に椎体圧潰または偽関節による神経障害をきたし、骨折固定術を施行した403例(男性89例、女性314例、平均73.8±7.8歳)を対象とした。術後1年以上にわたり経過観察を行い、術前と最終観察時のX線学的・臨床的アウトカムを評価した。平均手術時間は256.8±115.0分、平均出血量は676.3±1166.9gであり、周術期合併症の発症率は18.1%、せん妄を23例、硬膜破砕を5例、深部感染を4例、表在性感染を4例、血腫を4例、肺炎を3例、深部静脈血栓を3例に認めた。また、機器不全が41.2%にみられ、椎弓根スクリューの緩みが最も多かった。術前局所後彎角は22.0±16.9°であったが、5.2±13.1°に補正され、最終観察時には12.0±15.2°となっていた。腰痛と下肢痛のVASスコアは術後に有意に改善を示し、JOAスコアも最終観察時に有意な改善を認めた。歩行不能であったのは術前が52.4%であったが、最終観察時には7.5%に減少していた。偽関節を有する骨粗鬆症性椎体圧迫骨折に対して、骨折固定法は有用であることが示された。

  • Sarcopenia is related to spinal sagittal imbalance in patients with spinopelvic mismatch Reviewed

    Ohyama Shoichiro, Hoshino Masatoshi, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Takahashi Shinji, Hayashi Kazunori, Tamai Koji, Hori Yusuke, Nakamura Hiroaki

    EUROPEAN SPINE JOURNAL   28 ( 9 )   1929 - 1936   2019.09( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-06066-2

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  • Sarcopenia is related to spinal sagittal imbalance in patients with spinopelvic mismatch. Reviewed

    Ohyama S, Hoshino M, Terai H, Toyoda H, Suzuki A, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 9 )   1929 - 1936   2019.09( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-06066-2

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  • The factors related to the poor ADL in the patients with osteoporotic vertebral fracture after instrumentation surgery. Reviewed

    Murata K, Matsuoka Y, Nishimura H, Endo K, Suzuki H, Takamatsu T, Sawaji Y, Aihara T, Kusakabe T, Maekawa A, Yamamoto K, Watanabe K, Kaito T, Terai H, Tamai K, Tagami A, Yoshii T, Harimaya K, Kawaguchi K, Kimura A, Inoue G, Nakano A, Sakai D, Hiyama A, Ikegami S, Ohtori S, Furuya T, Orita S, Imagama S, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Uei H, Ajiro Y, Takahata M, Endo H, Abe T, Nakanishi K, Watanabe K, Okada E, Hosogane N, Funao H, Isogai N, Ishii K

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   2019.08( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-06092-0

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  • 特集 DISHの臨床 DISHの疫学 Reviewed

    豊田 宏光, 寺井 秀富, 山田 賢太郎, 中村 博亮

    脊椎脊髄ジャーナル   32 ( 7 )   653 - 660   2019.07( ISSN:09144412

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    DOI: 10.11477/mf.5002201171

  • 特集 DISHの臨床 腰椎変性疾患とDISH Reviewed

    山田 賢太郎, 豊田 宏光, 寺井 秀富, 中村 博亮

    脊椎脊髄ジャーナル   32 ( 7 )   685 - 692   2019.07( ISSN:09144412

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    DOI: 10.11477/mf.5002201177

  • Radiculopathy induced by calcification of multi-level lumbar ligamentum flavum : report of a case Reviewed

    70 ( 8 )   857 - 860   2019.07( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j_seikei70_857

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  • 【DISHの臨床】DISHの疫学 Reviewed

    豊田 宏光, 寺井 秀富, 山田 賢太郎, 中村 博亮

    (株)三輪書店 脊椎脊髄ジャーナル   32 ( 7 )   653 - 660   2019.07( ISSN:0914-4412

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    <文献概要>はじめに 近年,びまん性特発性骨増殖症(diffuse idiopathic skeletal hyperostosis:DISH)に対する関心が高まりつつある.DISHは前縦靱帯骨化を主病変とする病態から脊柱不撓性をもたらすものの,後縦靱帯骨化症(ossification of the posterior longitudinal ligament:OPLL)や黄色靱帯骨化症(ossification of the yellow ligament:OYL)とは異なり単独で神経障害や著しい疼痛をもたらすことはまれな疾患である.しかしながら,高齢者の脊椎疾患の治療を行っていると,DISHが背景に存在する脊椎外傷や変性疾患に遭遇することは少なくない.本稿では,DISHに関する本邦の臨床研究の歴史を振り返り,疫学知見に関するレビューを行った.

  • 【DISHの臨床】腰椎変性疾患とDISH Reviewed

    山田 賢太郎, 豊田 宏光, 寺井 秀富, 中村 博亮

    (株)三輪書店 脊椎脊髄ジャーナル   32 ( 7 )   685 - 692   2019.07( ISSN:0914-4412

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    <文献概要>はじめに Diffuse idiopathic skeletal hyperostosis(DISH)は,Resnickらにより定義された椎体に骨性架橋を認める病態である.DISHの弊害の中で脊椎脊髄外科医にとって最も特徴的なものは,DISHに伴う椎体骨折である.DISHによる椎体骨折は低エネルギー外傷で起こり得,遅発性神経麻痺,また骨折部の高度な不安定性に留意するべきと報告されている.これらはDISHによる骨性架橋による長いレバーアームのため,骨折部へ応力が集中され引き起こされると考えられている.同様の機序で,慢性疾患である腰部脊柱管狭窄症に対してもDISHは負の影響があると推察されるが,古くにDISHと脊柱管狭窄に関する症例報告がなされて以降,まとまった症例での報告は数少ない.本稿では,著者らの臨床研究結果も交えて,DISHの腰椎変性疾患への影響に焦点を当てて解説する.

  • Development of a scoring system for predicting adjacent vertebral fracture after balloon kyphoplasty. Reviewed

    Takahashi S, Hoshino M, Yasuda H, Hori Y, Ohyama S, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Toyoda H, Dohzono S, Sasaoka R, Kanematsu F, Nakamura H

    The spine journal : official journal of the North American Spine Society   19 ( 7 )   1194 - 1201   2019.07( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2019.02.013

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  • 【DISHの臨床】DISHの疫学 Reviewed

    豊田 宏光, 寺井 秀富, 山田 賢太郎, 中村 博亮

    脊椎脊髄ジャーナル   32 ( 7 )   653 - 660   2019.07( ISSN:0914-4412

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    Publishing type:Research paper (scientific journal)  

    <文献概要>はじめに 近年,びまん性特発性骨増殖症(diffuse idiopathic skeletal hyperostosis:DISH)に対する関心が高まりつつある.DISHは前縦靱帯骨化を主病変とする病態から脊柱不撓性をもたらすものの,後縦靱帯骨化症(ossification of the posterior longitudinal ligament:OPLL)や黄色靱帯骨化症(ossification of the yellow ligament:OYL)とは異なり単独で神経障害や著しい疼痛をもたらすことはまれな疾患である.しかしながら,高齢者の脊椎疾患の治療を行っていると,DISHが背景に存在する脊椎外傷や変性疾患に遭遇することは少なくない.本稿では,DISHに関する本邦の臨床研究の歴史を振り返り,疫学知見に関するレビューを行った.

  • 臨床室 多椎間腰椎黄色靱帯石灰化症により神経根性疼痛をきたした1例 Reviewed

    津本 柊子, 玉井 孝司, 久保 卓也, 藪 晋人, 寺井 秀富, 中村 博亮

    整形外科   70 ( 8 )   857 - 860   2019.07( ISSN:0030-5901

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    71歳女性。右下肢痛が出現し、黄色靱帯石灰化症による右L2/L3椎間孔部狭窄症と診断され、L2/L3右椎間孔拡大術が施行された。その後、黄色靱帯石灰化症による右L3/L4椎間孔部狭窄症に対しL3/L4椎間孔拡大術を施行した。今回、右下肢痛、しびれが再度出現し、黄色靱帯石灰化症によるL2/L3、L3/L4腰部脊柱管狭窄を認めたため、L2/L3、L3/L4顕微鏡下後方除圧術を行った。その結果、術後は右下肢の疼痛は速やかに改善したが、しびれは残存した。

  • 【DISHの臨床】腰椎変性疾患とDISH Reviewed

    山田 賢太郎, 豊田 宏光, 寺井 秀富, 中村 博亮

    脊椎脊髄ジャーナル   32 ( 7 )   685 - 692   2019.07( ISSN:0914-4412

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    <文献概要>はじめに Diffuse idiopathic skeletal hyperostosis(DISH)は,Resnickらにより定義された椎体に骨性架橋を認める病態である.DISHの弊害の中で脊椎脊髄外科医にとって最も特徴的なものは,DISHに伴う椎体骨折である.DISHによる椎体骨折は低エネルギー外傷で起こり得,遅発性神経麻痺,また骨折部の高度な不安定性に留意するべきと報告されている.これらはDISHによる骨性架橋による長いレバーアームのため,骨折部へ応力が集中され引き起こされると考えられている.同様の機序で,慢性疾患である腰部脊柱管狭窄症に対してもDISHは負の影響があると推察されるが,古くにDISHと脊柱管狭窄に関する症例報告がなされて以降,まとまった症例での報告は数少ない.本稿では,著者らの臨床研究結果も交えて,DISHの腰椎変性疾患への影響に焦点を当てて解説する.

  • Clinical Impact of Cervical Imbalance on Surgical Outcomes of Laminoplasty: A Propensity Score-Matching Analysis. Reviewed

    Tamai K, Suzuki A, Yabu A, Terai H, Hoshino M, Toyoda H, Takahashi S, Ohyama S, Hori Y, Nakamura H

    Clinical spine surgery   2019.05( ISSN:2380-0186

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    DOI: 10.1097/BSD.0000000000000849

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  • Answer to the Letter to the Editor concerning "The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders" by Toyoda H, et al. (Eur Spine J; doi.org/10.1007/s00586-018-5858-8). Reviewed

    Toyoda H, Hoshino M, Ohyama S, Terai H, Suzuki A, Yamada K, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 5 )   1252 - 1253   2019.05( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-05942-1

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  • ISSLS PRIZE IN CLINICAL SCIENCE 2019: clinical importance of trunk muscle mass for low back pain, spinal balance, and quality of life-a multicenter cross-sectional study. Reviewed

    Hori Y, Hoshino M, Inage K, Miyagi M, Takahashi S, Ohyama S, Suzuki A, Tsujio T, Terai H, Dohzono S, Sasaoka R, Toyoda H, Kato M, Matsumura A, Namikawa T, Seki M, Yamada K, Habibi H, Salimi H, Yamashita M, Yamauchi T, Furuya T, Orita S, Maki S, Shiga Y, Inoue M, Inoue G, Fujimaki H, Murata K, Kawakubo A, Kabata D, Shintani A, Ohtori S, Takaso M, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 5 )   914 - 921   2019.05( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-05904-7

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  • Impact of Hemodialysis on Surgical Outcomes and Mortality Rate after Lumbar Spine Surgery: A Matched Cohort Study

    Hori Yusuke, Takahashi Shinji, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Suzuki Akinobu, Hayashi Kazunori, Tamai Koji, Ohyama Shoichiro, Nakamura Hiroaki

    Spine Surgery and Related Research   3 ( 2 )   151 - 156   2019.04( eISSN:2432261X

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    <p>Introduction: Despite ongoing improvements in both dialysis and surgical techniques, spinal surgery in patients undergoing hemodialysis (HD) is a challenge to surgeons because of the high mortality rate. However, no previous studies have examined clinical outcomes after lumbar surgery in HD patients. The purpose of this study is to compare clinical outcomes and complication rates after lumbar spinal surgery in patients with or without hemodialysis.</p><p>Methods: This retrospective, matched cohort study was conducted to compare surgical outcomes between HD vs non-HD patients who underwent lumbar surgery at our hospital. Controls were individually matched to cases at a ratio of 1:2. Clinical outcomes, complications, and mortality rates were compared between the two groups.</p><p>Results: Twenty-nine patients in the HD group and 57 in the non-HD group were included in the current study. Five patients in the HD group died during the follow-up period, whereas no patients died in the non-HD group (mortality rate, 17.2% vs. 0%, <i>P</i> = 0.003). Japanese Orthopaedic Association (JOA) scores were significantly less improved in the HD group than in the non-HD group (11.9 vs. 14.2 preoperatively, <i>P</i> = 0.001; 19.9 vs. 25.1 at final follow-up, <i>P</i> < 0.001). Five patients underwent repeat surgery in the HD group, which was significantly higher than the non-HD group (17.2% vs. 3.5%, <i>P</i> = 0.041).</p><p>Conclusions: The current study indicates that patients undergoing HD had poor outcomes after lumbar spinal surgery. Moreover, 5 of 29 patients died within a mean 2.4-years follow-up. The indications for lumbar spine surgery in HD patients must be carefully considered because of poor surgical outcomes and high mortality rate.</p>

    DOI: 10.22603/ssrr.2018-0025

    PubMed

    CiNii Article

  • Risk Factors for Proximal Junctional Fracture Following Fusion Surgery for Osteoporotic Vertebral Collapse with Delayed Neurological Deficits: A Retrospective Cohort Study of 403 Patients

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki, Watanabe Kei, Katsumi Keiichi, Ohashi Masayuki, Shibuya Yohei, Izumi Tomohiro, Hirano Toru, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Yoshii Toshitaka, Ushio Shuta, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Nakano Atsushi, Sakai Daisuke, Nukaga Tadashi, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Ohtori Seiji, Furuya Takeo, Orita Sumihisa, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Kiyasu Katsuhito, Murakami Hideki, Yoshioka Katsuhito, Seki Shoji, Hongo Michio, Kakutani Kenichiro, Yurube Takashi, Aoki Yasuchika, Oshima Masashi, Takahata Masahiko, Iwata Akira, Endo Hirooki, Abe Tetsuya, Tsukanishi Toshinori, Nakanishi Kazuyoshi, Watanabe Kota, Hikata Tomohiro, Suzuki Satoshi, Isogai Norihiro, Okada Eijiro, Funao Haruki, Ueda Seiji, Shiono Yuta, Nojiri Kenya, Hosogane Naobumi, Ishii Ken

    Spine Surgery and Related Research   3 ( 2 )   171 - 177   2019.04( ISSN:2432261X ( eISSN:2432261X

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    <p>Introduction: Approximately 3% of osteoporotic vertebral fractures develop osteoporotic vertebral collapse (OVC) with neurological deficits, and such patients are recommended to be treated surgically. However, a proximal junctional fracture (PJFr) following surgery for OVC can be a serious concern. Therefore, the aim of this study is to identify the incidence and risk factors of PJFr following fusion surgery for OVC.</p><p>Methods: This study retrospectively analyzed registry data collected from facilities belonging to the Japan Association of Spine Surgeons with Ambition (JASA) in 2016. We retrospectively analyzed 403 patients who suffered neurological deficits due to OVC below T10 and underwent corrective surgery; only those followed up for ≥2 years were included. Potential risk factors related to the PJFr and their cut-off values were calculated using multivariate logistic regression analysis and receiver operating characteristic (ROC) analysis.</p><p>Results: Sixty-three patients (15.6%) suffered PJFr during the follow-up (mean 45.7 months). In multivariate analysis, the grade of osteoporosis (grade 2, 3: adjusted odds ratio (aOR) 2.92; p=0.001) and lower instrumented vertebra (LIV) level (sacrum: aOR 6.75; p=0.003) were independent factors. ROC analysis demonstrated that lumbar bone mineral density (BMD) was a predictive factor (area under curve: 0.72, p=0.035) with optimal cut-off value of 0.61 g/cm<sup>2</sup> (sensitivity, 76.5%; specificity, 58.3%), but that of the hip was not (p=0.228).</p><p>Conclusions: PJFr was found in 16% cases within 4 years after surgery; independent risk factors were severe osteoporosis and extended fusion to the sacrum. The lumbar BMD with cut-off value 0.61 g/cm<sup>2</sup> may potentially predict PJFr. Our findings can help surgeons select perioperative adjuvant therapy, as well as a surgical strategy to prevent PJFr following surgery.</p>

    DOI: 10.22603/ssrr.2018-0068

    PubMed

    CiNii Article

  • 誌上シンポジウム 超高齢社会における脊椎手術 骨粗鬆症性脊椎椎体骨折に対する脊椎固定術 Reviewed

    寺井 秀富

    臨床整形外科   54 ( 4 )   351 - 360   2019.04( ISSN:05570433 ( eISSN:18821286

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    DOI: 10.11477/mf.1408201329

  • Risk Factors for Proximal Junctional Fracture Following Fusion Surgery for Osteoporotic Vertebral Collapse with Delayed Neurological Deficits: A Retrospective Cohort Study of 403 Patients(和訳中) Reviewed

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki, Watanabe Kei, Katsumi Keiichi, Ohashi Masayuki, Shibuya Yohei, Izumi Tomohiro, Hirano Toru, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Yoshii Toshitaka, Ushio Shuta, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Nakano Atsushi, Sakai Daisuke, Nukaga Tadashi, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Ohtori Seiji, Furuya Takeo, Orita Sumihisa, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Kiyasu Katsuhito, Murakami Hideki, Yoshioka Katsuhito, Seki Shoji, Hongo Michio, Kakutani Kenichiro, Yurube Takashi, Aoki Yasuchika, Oshima Masashi, Takahata Masahiko, Iwata Akira, Endo Hirooki, Abe Tetsuya, Tsukanishi Toshinori, Nakanishi Kazuyoshi, Watanabe Kota, Hikata Tomohiro, Suzuki Satoshi, Isogai Norihiro, Okada Eijiro, Funao Haruki, Ueda Seiji, Shiono Yuta, Nojiri Kenya, Hosogane Naobumi, Ishii Ken

    (一社)日本脊椎脊髄病学会 Spine Surgery and Related Research   3 ( 2 )   171 - 177   2019.04

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  • 超高齢社会における脊椎手術 骨粗鬆症性脊椎椎体骨折に対する脊椎固定術 Reviewed

    寺井 秀富

    (株)医学書院 臨床整形外科   54 ( 4 )   351 - 360   2019.04( ISSN:0557-0433

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    <文献概要>超高齢社会の現在,骨粗鬆症性椎体骨折(OVFs)に対する治療は大きな問題である.従来,保存療法と薬物療法が基本とされてきたが,奏効しない場合には外科的介入が必要となる.椎体形成術の登場によりOVFsに対する治療戦略は大きく変化したが,椎体形成術だけで解決できない椎体骨折例も多数存在し,それらに対しては脊椎固定術が必要となる.脊椎固定の手術手技はIn situ固定,椎体形成術+後方固定,骨切り,前方固定など多岐にわたり,病態に応じた術式の選択と合併症を回避する高度な技術力が要求される.

  • 腰椎手術後の手術成績と死亡率に対する血液透析の影響 対応コホート研究(Impact of Hemodialysis on Surgical Outcomes and Mortality Rate after Lumbar Spine Surgery: A Matched Cohort Study) Reviewed

    Hori Yusuke, Takahashi Shinji, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Suzuki Akinobu, Hayashi Kazunori, Tamai Koji, Ohyama Shoichiro, Nakamura Hiroaki

    Spine Surgery and Related Research   3 ( 2 )   151 - 156   2019.04

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    腰椎手術後の臨床転帰と合併症率を血液透析(HD)の有無で比較した。2010年1月〜2015年12月に当施設で腰椎手術を施行されたHD患者と非HD患者を比較する後ろ向き対応コホート研究を実施した。臨床転帰は日本整形外科学会(JOA)スコアで、腰痛、下肢痛、下肢のしびれは視覚アナログスケール(VAS)で評価した。HD群29例(男性58.6%、平均69.7±6.8歳)と非HD群57例(男性57.9%、平均70.1±6.7歳)を比較した。HD群のJOAスコアは8.0改善し、非HD群の10.9よりも改善度が有意に低かった。腰痛、下肢痛、下肢のしびれに対するVASスコアの改善はHD群と非HD群で差はなかった。経過観察期間中、HD群では5例が死亡したのに対し、非HD群では死亡が認められず、死亡率はHD群が有意に高かった。再手術率はHD群が17.2%で非HD群の3.5%よりも有意に高かった。

  • 遅発性神経障害を伴った骨粗鬆症性椎体圧潰に対する固定術後のproximal junctional fractureの危険因子 患者403例の後ろ向きコホート研究(Risk Factors for Proximal Junctional Fracture Following Fusion Surgery for Osteoporotic Vertebral Collapse with Delayed Neurological Deficits: A Retrospective Cohort Study of 403 Patients) Reviewed

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki, Watanabe Kei, Katsumi Keiichi, Ohashi Masayuki, Shibuya Yohei, Izumi Tomohiro, Hirano Toru, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Yoshii Toshitaka, Ushio Shuta, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Nakano Atsushi, Sakai Daisuke, Nukaga Tadashi, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Ohtori Seiji, Furuya Takeo, Orita Sumihisa, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Kiyasu Katsuhito, Murakami Hideki, Yoshioka Katsuhito, Seki Shoji, Hongo Michio, Kakutani Kenichiro, Yurube Takashi, Aoki Yasuchika, Oshima Masashi, Takahata Masahiko, Iwata Akira, Endo Hirooki, Abe Tetsuya, Tsukanishi Toshinori, Nakanishi Kazuyoshi, Watanabe Kota, Hikata Tomohiro, Suzuki Satoshi, Isogai Norihiro, Okada Eijiro, Funao Haruki, Ueda Seiji, Shiono Yuta, Nojiri Kenya, Hosogane Naobumi, Ishii Ken

    Spine Surgery and Related Research   3 ( 2 )   171 - 177   2019.04

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    骨粗鬆症性椎体圧潰(OVC)に対する外科的治療後のproximal junctional fracture(PJFr)の発生率と独立危険因子を同定した。Japan Association of Spine Surgeons with Ambitionに所属する機関の2016年の登録データを後ろ向きに解析した。T10以下のOVCによる神経障害に対して矯正手術を実施し、2年以上経過観察を行った403例(女性331例、男性72例、平均73.8±7.8歳)を解析した。63例にPJFrを認めた。多重ロジスティック回帰分析の結果、骨粗鬆症のグレードとlower instrumented vertebraレベルがPJFrの独立危険因子であった。受信者動作特性曲線解析では、腰椎骨密度が良好な予測能の有意な因子であったが、股関節骨密度は有意な因子ではなかった。初回手術後のPJFrの予測に対する最適カットオフ値は腰椎骨密度0.61g/cm2であった。

  • 超高齢社会における脊椎手術 骨粗鬆症性脊椎椎体骨折に対する脊椎固定術 Reviewed

    寺井 秀富

    臨床整形外科   54 ( 4 )   351 - 360   2019.04( ISSN:0557-0433

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    Publishing type:Research paper (scientific journal)  

    <文献概要>超高齢社会の現在,骨粗鬆症性椎体骨折(OVFs)に対する治療は大きな問題である.従来,保存療法と薬物療法が基本とされてきたが,奏効しない場合には外科的介入が必要となる.椎体形成術の登場によりOVFsに対する治療戦略は大きく変化したが,椎体形成術だけで解決できない椎体骨折例も多数存在し,それらに対しては脊椎固定術が必要となる.脊椎固定の手術手技はIn situ固定,椎体形成術+後方固定,骨切り,前方固定など多岐にわたり,病態に応じた術式の選択と合併症を回避する高度な技術力が要求される.

  • Surgical outcomes of spinal fusion for osteoporotic thoracolumbar vertebral fractures in patients with Parkinson's disease: what is the impact of Parkinson's disease on surgical outcome? Reviewed

    Watanabe Kei, Katsumi Keiichi, Ohashi Masayuki, Shibuya Yohei, Izumi Tomohiro, Hirano Toru, Endo Naoto, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Terai Hidetomi, Tamai Koji, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Yoshii Toshitaka, Ushio Shuta, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Nakano Atsushi, Sakai Daisuke, Nukaga Tadashi, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Ohtori Seiji, Furuya Takeo, Orita Sumihisa, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Kiyasu Katsuhito, Murakami Hideki, Yoshioka Katsuhito, Seki Shoji, Hongo Michio, Kakutani Kenichiro, Yurube Takashi, Aoki Yasuchika, Oshima Masashi, Takahata Masahiko, Iwata Akira, Endo Hirooki, Abe Tetsuya, Tsukanishi Toshinori, Nakanishi Kazuyoshi, Watanabe Kota, Hikata Tomohiro, Suzuki Satoshi, Isogai Norihiro, Okada Eijiro, Funao Haruki, Ueda Seiji, Shiono Yuta, Nojiri Kenya, Hosogane Naobumi, Ishii Ken

    BMC MUSCULOSKELETAL DISORDERS   20 ( 1 )   103   2019.03( ISSN:1471-2474

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    DOI: 10.1186/s12891-019-2473-8

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  • Surgical outcomes of spinal fusion for osteoporotic thoracolumbar vertebral fractures in patients with Parkinson's disease: what is the impact of Parkinson's disease on surgical outcome? Reviewed

    Watanabe K, Katsumi K, Ohashi M, Shibuya Y, Izumi T, Hirano T, Endo N, Kaito T, Yamashita T, Fujiwara H, Nagamoto Y, Matsuoka Y, Suzuki H, Nishimura H, Terai H, Tamai K, Tagami A, Yamada S, Adachi S, Yoshii T, Ushio S, Harimaya K, Kawaguchi K, Yokoyama N, Oishi H, Doi T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Nakano A, Sakai D, Nukaga T, Ikegami S, Shimizu M, Futatsugi T, Ohtori S, Furuya T, Orita S, Imagama S, Ando K, Kobayashi K, Kiyasu K, Murakami H, Yoshioka K, Seki S, Hongo M, Kakutani K, Yurube T, Aoki Y, Oshima M, Takahata M, Iwata A, Endo H, Abe T, Tsukanishi T, Nakanishi K, Watanabe K, Hikata T, Suzuki S, Isogai N, Okada E, Funao H, Ueda S, Shiono Y, Nojiri K, Hosogane N, Ishii K

    BMC musculoskeletal disorders   20 ( 1 )   103   2019.03

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    DOI: 10.1186/s12891-019-2473-8

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  • Answer to the Letter to the Editor concerning "The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders" by Toyoda H, et al. (Eur Spine J; doi.org/10.1007/s00586-018-5858-8). Reviewed

    Toyoda H, Hoshino M, Ohyama S, Terai H, Suzuki A, Yamada K, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   2019.03( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-05942-1

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  • Cost-effectiveness of Balloon Kyphoplasty for Patients With Acute/Subacute Osteoporotic Vertebral Fractures in the Super-Aging Japanese Society. Reviewed

    Takahashi S, Hoshino M, Yasuda H, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Ohyama S, Toyoda H, Dohzono S, Kanematsu F, Hori Y, Nakamura H

    Spine   44 ( 5 )   E298 - E305   2019.03( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000002829

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  • Development of a scoring system for predicting adjacent vertebral fracture after balloon kyphoplasty. Reviewed

    Takahashi S, Hoshino M, Yasuda H, Hori Y, Ohyama S, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Toyoda H, Dohzono S, Sasaoka R, Kanematsu F, Nakamura H

    The spine journal : official journal of the North American Spine Society   2019.03( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2019.02.013

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  • Cost-effectiveness of Balloon Kyphoplasty for Patients With Acute/Subacute Osteoporotic Vertebral Fractures in the Super-Aging Japanese Society. Reviewed

    Takahashi S, Hoshino M, Yasuda H, Terai H, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Ohyama S, Toyoda H, Dohzono S, Kanematsu F, Hori Y, Nakamura H

    Spine   44 ( 5 )   E298 - E305   2019.03( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000002829

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  • ISSLS PRIZE IN CLINICAL SCIENCE 2019: clinical importance of trunk muscle mass for low back pain, spinal balance, and quality of life-a multicenter cross-sectional study. Reviewed

    Hori Y, Hoshino M, Inage K, Miyagi M, Takahashi S, Ohyama S, Suzuki A, Tsujio T, Terai H, Dohzono S, Sasaoka R, Toyoda H, Kato M, Matsumura A, Namikawa T, Seki M, Yamada K, Habibi H, Salimi H, Yamashita M, Yamauchi T, Furuya T, Orita S, Maki S, Shiga Y, Inoue M, Inoue G, Fujimaki H, Murata K, Kawakubo A, Kabata D, Shintani A, Ohtori S, Takaso M, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   2019.02( ISSN:0940-6719

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    DOI: 10.1007/s00586-019-05904-7

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  • Preoperative severity of facet joint degeneration does not impact the 2-year clinical outcomes and cervical imbalance following laminoplasty Reviewed

    Tamai Koji, Suzuki Akinobu, Yabu Akito, Takahashi Shinji, Toyoda Hiromitsu, Hoshino Masatoshi, Terai Hidetomi, Nakamura Hiroaki

    SPINE JOURNAL   19 ( 2 )   246 - 252   2019.02( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2018.06.343

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  • The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders Reviewed

    Toyoda Hiromitsu, Hoshino Masatoshi, Ohyama Shoichiro, Terai Hidetomi, Suzuki Akinobu, Yamada Kentaro, Takahashi Shinji, Hayashi Kazunori, Tamai Koji, Hori Yusuke, Nakamura Hiroaki

    EUROPEAN SPINE JOURNAL   28 ( 2 )   241 - 249   2019.02( ISSN:0940-6719

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    DOI: 10.1007/s00586-018-5858-8

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  • Preoperative severity of facet joint degeneration does not impact the 2-year clinical outcomes and cervical imbalance following laminoplasty. Reviewed

    Tamai K, Suzuki A, Yabu A, Takahashi S, Toyoda H, Hoshino M, Terai H, Nakamura H

    The spine journal : official journal of the North American Spine Society   19 ( 2 )   246 - 252   2019.02( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2018.06.343

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  • The association of back muscle strength and sarcopenia-related parameters in the patients with spinal disorders. Reviewed

    Toyoda H, Hoshino M, Ohyama S, Terai H, Suzuki A, Yamada K, Takahashi S, Hayashi K, Tamai K, Hori Y, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   28 ( 2 )   241 - 249   2019.02( ISSN:0940-6719

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    DOI: 10.1007/s00586-018-5858-8

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  • Balloon Kyphoplasty Versus Conservative Treatment for Acute Osteoporotic Vertebral Fractures With Poor Prognostic Factors: Propensity Score Matched Analysis Using Data From Two Prospective Multicenter Studies. Reviewed

    Hoshino M, Takahashi S, Yasuda H, Terai H, Watanabe K, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Ohyama S, Toyoda H, Dohzono S, Kanematsu F, Hori Y, Nakamura H

    Spine   44 ( 2 )   110 - 117   2019.01( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000002769

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  • Balloon Kyphoplasty Versus Conservative Treatment for Acute Osteoporotic Vertebral Fractures With Poor Prognostic Factors: Propensity Score Matched Analysis Using Data From Two Prospective Multicenter Studies. Reviewed

    Hoshino M, Takahashi S, Yasuda H, Terai H, Watanabe K, Hayashi K, Tsujio T, Kono H, Suzuki A, Tamai K, Ohyama S, Toyoda H, Dohzono S, Kanematsu F, Hori Y, Nakamura H

    Spine   44 ( 2 )   110 - 117   2019.01( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000002769

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  • Surgical Treatment of a Patient with Prolonged Exacerbation of Hirayama Disease(和訳中) Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Tamura Akiko, Hayashi Kazunori, Terai Hidetomi, Nakamura Hiroaki

    (一社)日本脊椎脊髄病学会 Spine Surgery and Related Research   3 ( 1 )   95 - 97   2019.01

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  • Anatomical analysis of the human ligamentum flavum in the thoracic spine: Clinical implications for posterior thoracic spinal surgery(和訳中) Reviewed

    Ahmadi Sayed Abdullah, Suzuki Akinobu, Terai Hidetomi, Tamai Koji, Akhgar Javid, Hoshino Masatoshi, Toyoda Hiromitsu, Rahmani Mohammad Suhrab, Hayashi Kazunori, Ohyama Shoichiro, Takahashi Shinji, Nakamura Hiroaki

    (公社)日本整形外科学会 Journal of Orthopaedic Science   24 ( 1 )   62 - 67   2019.01( ISSN:0949-2658

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  • Anatomical analysis of the human ligamentum flavum in the thoracic spine: Clinical implications for posterior thoracic spinal surgery Reviewed

    Ahmadi Sayed Abdullah, Suzuki Akinobu, Terai Hidetomi, Tamai Koji, Akhgar Javid, Hoshino Masatoshi, Toyoda Hiromitsu, Rahmani Mohammad Suhrab, Hayashi Kazunori, Ohyama Shoichiro, Takahashi Shinji, Nakamura Hiroaki

    JOURNAL OF ORTHOPAEDIC SCIENCE   24 ( 1 )   62 - 67   2019.01( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2018.08.023

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  • 広汎性特発性骨増殖症は手術を必要とする腰部脊柱管狭窄症と関連する(Diffuse idiopathic skeletal hyperostosis is associated with lumbar spinal stenosis requiring surgery) Reviewed

    Yamada Kentaro, Satoh Shigenobu, Hashizume Hiroshi, Yoshimura Noriko, Kagotani Ryohei, Ishimoto Yuyu, Abe Yuichiro, Toyoda Hiromitsu, Terai Hidetomi, Masuda Takeshi, Muraki Shigeyuki, Nakamura Hiroaki, Yoshida Munehito

    (一社)日本骨代謝学会 Journal of Bone and Mineral Metabolism   37 ( 1 )   118 - 124   2019.01( ISSN:0914-8779

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    手術を必要とする腰部脊柱管狭窄症(LSS)患者とLSSの症状のない被験者における広汎性特発性骨増殖症(DISH)の有病率を調査し、手術を必要とするLSSとDISHとの関連を明らかにした。症候性LSSに対して手術を実施した患者2363例(男性49.8%、平均68.0±8.4歳)とLSSのない対照787例(男性33.4%、平均67.2±12.4歳)を調査した。DISHの有病率はX線検査でLSSのない無症候性対照では14.4%、X線検査でLSSのある無症候性対照では21.1%、手術を必要とするLSS患者では31.7%で、有意に増加した。DISHの分布は群間で同様であったが、手術を必要とするLSS患者では胸郭下部と上部中央腰椎域の頻度が高かった。年齢、性別、BMI、糖尿病の補正後、多変量解析ではDISHが手術を必要とするLSSに関連する独立因子であった。手術を必要とするLSS患者では、DISHのない患者よりも手術を必要とするDISH患者において、腰椎上部での狭窄と多層狭窄の高発生率が観察された。DISHによる下部可動域における減少によって、LSSの発症または重度が増加することが示唆された。

  • Anatomical analysis of the human ligamentum flavum in the thoracic spine: Clinical implications for posterior thoracic spinal surgery. Reviewed

    Ahmadi SA, Suzuki A, Terai H, Tamai K, Akhgar J, Hoshino M, Toyoda H, Rahmani MS, Hayashi K, Ohyama S, Takahashi S, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   24 ( 1 )   62 - 67   2019.01( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2018.08.023

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  • Efficacy of afatinib or osimertinib plus cetuximab combination therapy for non-small-cell lung cancer with EGFR exon 20 insertion mutations. Reviewed

    Hasegawa H, Yasuda H, Hamamoto J, Masuzawa K, Tani T, Nukaga S, Hirano T, Kobayashi K, Manabe T, Terai H, Ikemura S, Kawada I, Naoki K, Soejima K

    Lung cancer (Amsterdam, Netherlands)   127   146 - 152   2019.01( ISSN:0169-5002

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    DOI: 10.1016/j.lungcan.2018.11.039

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  • Diffuse idiopathic skeletal hyperostosis is associated with lumbar spinal stenosis requiring surgery. Reviewed

    Yamada K, Satoh S, Hashizume H, Yoshimura N, Kagotani R, Ishimoto Y, Abe Y, Toyoda H, Terai H, Masuda T, Muraki S, Nakamura H, Yoshida M

    Journal of bone and mineral metabolism   37 ( 1 )   118 - 124   2019.01( ISSN:0914-8779

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    DOI: 10.1007/s00774-017-0901-0

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  • 平山病の長期悪化患者に対する外科的治療(Surgical Treatment of a Patient with Prolonged Exacerbation of Hirayama Disease) Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Tamura Akiko, Hayashi Kazunori, Terai Hidetomi, Nakamura Hiroaki

    Spine Surgery and Related Research   3 ( 1 )   95 - 97   2019.01

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    症例は48歳女性で、右遠位上手部と前腕の進行性脱力を呈していた。症状は15歳時に始まり、右手の冷感も伴っていた。3年後には右手指の伸展が困難となり、寒冷気候中では巧緻運動障害も経験していた。筋力低下の悪化も進行し、近位同側下肢の緩徐な進行性脱力も現れたため当院に来院した。神経学的検査で、右遠位上肢の顕著な萎縮と鷲手変形が明らかとなり、罹患した前腕の尺骨側と手で中程度から重度の感覚障害が観察された。頸部MRIでは、C4-5、C5-6、C6-7レベルでのT2強調画像上に高輝度領域を伴う非対称な前後方向平坦化が見られ、屈位の頸部MRIでは後部硬膜壁の変位がない脊髄前方移動、当該脊髄のC4-5およびC5-6レベルでの圧迫が明らかとなった。C4-5およびC5-6レベルでの前方除圧固定術を行い、ポリエーテルエーテルケトンケージを各椎体間スペースに配置して頸椎前彎を達成した。術後2年で右足は完全な強さを維持しているが、右遠位上肢の顕著な萎縮と鷲手変形は残存している。

  • 胸椎におけるヒト黄色靱帯の解剖学的解析 後胸椎手術の臨床適応(Anatomical analysis of the human ligamentum flavum in the thoracic spine: Clinical implications for posterior thoracic spinal surgery) Reviewed

    Ahmadi Sayed Abdullah, Suzuki Akinobu, Terai Hidetomi, Tamai Koji, Akhgar Javid, Hoshino Masatoshi, Toyoda Hiromitsu, Rahmani Mohammad Suhrab, Hayashi Kazunori, Ohyama Shoichiro, Takahashi Shinji, Nakamura Hiroaki

    Journal of Orthopaedic Science   24 ( 1 )   62 - 67   2019.01( ISSN:0949-2658

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    防腐処理死体20検体を用いて、胸椎黄色靱帯の解剖学的解明を試みた。全椎体を採取後に椎弓根を垂直面で切断、T1/T2からT12/L1の黄色靱帯を造影剤で染色し、CT像によって形状と椎体骨構造との関係を評価した。その結果、胸椎の層間腔内に左右二つの黄色靱帯が存在しており、腹側でcranial laminae、背側でcaudal laminaeを被覆していた。正中における黄色靱帯の高さは頭側から尾側に向かって徐々に増大しており、平均高はT1/T2で11.8±1.6mm、T12/L1で15.1±0.1mmを示していた。黄色靱帯の幅も頭側から尾側にかけて緩やかに増加しており、平均幅はT1/T2で13.8±1.4mm、T12/L1で17.8±1.6mmであった。なお、いずれの脊椎レベルでも幅に有意な左右差はなかった。また、黄色靱帯によるcaudal laminaの被覆率は上位脊椎から下位脊椎に向かって徐々に増加し、平均被覆率はT1で31.7%、T12で41.7%であったが、cranial laminaの被覆率は減少しており、平均被覆率はT2で12.6%、L1で4.3%であった。黄色靱帯で被覆されない空白域に関して脊椎レベルでの差はなく、平均53.9±2.5%を示していた。胸椎椎間孔において、黄色靱帯は椎間関節をT2/T3からT12/L1のレベルで被覆していたが、T1/T2レベルでの被覆はみられなかった。

  • 広汎性特発性骨増殖症は手術を必要とする腰部脊柱管狭窄症と関連する(Diffuse idiopathic skeletal hyperostosis is associated with lumbar spinal stenosis requiring surgery) Reviewed

    Yamada Kentaro, Satoh Shigenobu, Hashizume Hiroshi, Yoshimura Noriko, Kagotani Ryohei, Ishimoto Yuyu, Abe Yuichiro, Toyoda Hiromitsu, Terai Hidetomi, Masuda Takeshi, Muraki Shigeyuki, Nakamura Hiroaki, Yoshida Munehito

    Journal of Bone and Mineral Metabolism   37 ( 1 )   118 - 124   2019.01( ISSN:0914-8779

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    手術を必要とする腰部脊柱管狭窄症(LSS)患者とLSSの症状のない被験者における広汎性特発性骨増殖症(DISH)の有病率を調査し、手術を必要とするLSSとDISHとの関連を明らかにした。症候性LSSに対して手術を実施した患者2363例(男性49.8%、平均68.0±8.4歳)とLSSのない対照787例(男性33.4%、平均67.2±12.4歳)を調査した。DISHの有病率はX線検査でLSSのない無症候性対照では14.4%、X線検査でLSSのある無症候性対照では21.1%、手術を必要とするLSS患者では31.7%で、有意に増加した。DISHの分布は群間で同様であったが、手術を必要とするLSS患者では胸郭下部と上部中央腰椎域の頻度が高かった。年齢、性別、BMI、糖尿病の補正後、多変量解析ではDISHが手術を必要とするLSSに関連する独立因子であった。手術を必要とするLSS患者では、DISHのない患者よりも手術を必要とするDISH患者において、腰椎上部での狭窄と多層狭窄の高発生率が観察された。DISHによる下部可動域における減少によって、LSSの発症または重度が増加することが示唆された。

  • Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit-A Nationwide Multicenter Study in Japan- Reviewed

    Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Funao Haruki, Okada Eijiro, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshio, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    一般社団法人 日本脊椎脊髄病学会 SPINE SURGERY AND RELATED RESEARCH   3 ( 4 )   361 - 367   2019( ISSN:2432-261X

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    <p>Introduction: The prevalence of patients with osteoporosis continues to increase in aging societies, including Japan. The first choice for managing osteoporotic vertebral compression fracture (OVF) is conservative treatment. Failure in conservative treatment for OVF may lead to non-union or vertebral collapse, resulting in neurological deficit and subsequently requiring surgical intervention. This multicenter nationwide study in Japan was conducted to comprehensively understand the outcomes of surgical treatments for OVF non-union.</p><p>Methods: This multicenter, retrospective study included 403 patients (89 males, 314 females, mean age 73.8 ± 7.8 years, mean follow-up 3.9 ± 1.7 years) with neurological deficit due to vertebral collapse or non-union after OVF at T10-L5 who underwent fusion surgery with a minimum 1-year follow-up. Radiological and clinical outcomes at baseline and at the final follow-up (FU) were evaluated.</p><p>Results: OVF was present at a thoracolumbar junction such as T12 (124 patients) and L1 (117 patients). A majority of OVF occurred after a minor trauma, such as falling down (55.3%) or lifting objects (8.4%). Short segment fusion, including affected vertebra, was conducted (mean 4.0 ± 2.0 vertebrae) with 256.8 minutes of surgery and 676.1 g of blood loss. A posterior approach was employed in 86.6% of the patients, followed by a combined anterior and posterior (8.7%), and an anterior (4.7%) approach. Perioperative complications and implant failures were observed in 18.1% and 41.2%, respectively. VAS scores of low back pain (74.7 to 30.8 mm) and leg pain (56.8 to 20.7 mm) improved significantly at FU. Preoperatively, 52.6% of the patients were unable to walk and the rate of non-ambulatory patients decreased to 7.5% at FU.</p><p>Conclusions: This study demonstrated that substantial improvement in activity of daily living (ADL) was achieved by fusion surgery. Although there was a considerable rate of complications, fusion surgery is beneficial for elderly OVF patients with non-union.</p>

    DOI: 10.22603/ssrr.2019-0004

    CiNii Article

  • General Anesthesia Management for Adult Mucopolysaccharidosis Patients Undergoing Major Spine Surgery. Reviewed

    Tsuchiya M, Terai H, Mizutani K, Funai Y, Tanaka K, Yamada T, Mori T, Nishikawa K

    Medical principles and practice : international journal of the Kuwait University, Health Science Centre   28 ( 6 )   581 - 585   2019( ISSN:1011-7571

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    DOI: 10.1159/000503051

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  • Surgical Treatment of Osteoporotic Vertebral Fracture with Neurological Deficit-A Nationwide Multicenter Study in Japan-

    Hosogane Naobumi, Nojiri Kenya, Suzuki Satoshi, Funao Haruki, Okada Eijiro, Isogai Norihiro, Ueda Seiji, Hikata Tomohiro, Shiono Yuta, Watanabe Kota, Watanabe Kei, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Terai Hidetomi, Tamai Koji, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Adachi Shinji, Ohtori Seiji, Orita Sumihisa, Furuya Takeo, Yoshii Toshitaka, Ushio Shuta, Inoue Gen, Miyagi Masayuki, Saito Wataru, Imagama Shiro, Ando Kei, Sakai Daisuke, Nukaga Tadashi, Kiyasu Katsuhito, Kimura Atsushi, Inoue Hirokazu, Nakano Atsushi, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshio, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Kakutani Kenichiro, Yurube Takashi, Oshima Masashi, Uei Hiroshi, Aoki Yasuchika, Takahata Masahiko, Iwata Akira, Seki Shoji, Murakami Hideki, Yoshioka Katsuhito, Endo Hirooki, Hongo Michio, Nakanishi Kazuyoshi, Abe Tetsuya, Tsukanishi Toshinori, Ishii Ken

    Spine Surgery and Related Research   3 ( 4 )   361 - 367   2019( eISSN:2432261X

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    <p>Introduction: The prevalence of patients with osteoporosis continues to increase in aging societies, including Japan. The first choice for managing osteoporotic vertebral compression fracture (OVF) is conservative treatment. Failure in conservative treatment for OVF may lead to non-union or vertebral collapse, resulting in neurological deficit and subsequently requiring surgical intervention. This multicenter nationwide study in Japan was conducted to comprehensively understand the outcomes of surgical treatments for OVF non-union.</p><p>Methods: This multicenter, retrospective study included 403 patients (89 males, 314 females, mean age 73.8 ± 7.8 years, mean follow-up 3.9 ± 1.7 years) with neurological deficit due to vertebral collapse or non-union after OVF at T10-L5 who underwent fusion surgery with a minimum 1-year follow-up. Radiological and clinical outcomes at baseline and at the final follow-up (FU) were evaluated.</p><p>Results: OVF was present at a thoracolumbar junction such as T12 (124 patients) and L1 (117 patients). A majority of OVF occurred after a minor trauma, such as falling down (55.3%) or lifting objects (8.4%). Short segment fusion, including affected vertebra, was conducted (mean 4.0 ± 2.0 vertebrae) with 256.8 minutes of surgery and 676.1 g of blood loss. A posterior approach was employed in 86.6% of the patients, followed by a combined anterior and posterior (8.7%), and an anterior (4.7%) approach. Perioperative complications and implant failures were observed in 18.1% and 41.2%, respectively. VAS scores of low back pain (74.7 to 30.8 mm) and leg pain (56.8 to 20.7 mm) improved significantly at FU. Preoperatively, 52.6% of the patients were unable to walk and the rate of non-ambulatory patients decreased to 7.5% at FU.</p><p>Conclusions: This study demonstrated that substantial improvement in activity of daily living (ADL) was achieved by fusion surgery. Although there was a considerable rate of complications, fusion surgery is beneficial for elderly OVF patients with non-union.</p>

    DOI: 10.22603/ssrr.2019-0004

    PubMed

    CiNii Article

  • Comparison of minimally invasive decompression and combined minimally invasive decompression and fusion in patients with degenerative spondylolisthesis with instability Reviewed

    Hayashi Kazunori, Toyoda Hiromitsu, Terai Hidetomi, Hoshino Masatoshi, Suzuki Akinobu, Takahashi Shinji, Tamai Koji, Ohyama Shoichiro, Hori Yusuke, Yabu Akito, Nakamura Hiroaki

    JOURNAL OF CLINICAL NEUROSCIENCE   57   79 - 85   2018.11( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2018.08.032

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  • Spinopelvic Sagittal Alignment after Microendoscopic Laminotomy in Patients with Lumbar Degenerative Spondylolisthesis Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Hori Yusuke, Takahashi Shinji, Suzuki Akinobu, Terai Hidetomi, Nakamura Hiroaki

    JOURNAL OF NEUROLOGICAL SURGERY PART A-CENTRAL EUROPEAN NEUROSURGERY   79 ( 6 )   479 - 485   2018.11( ISSN:2193-6315

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    DOI: 10.1055/s-0038-1666847

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  • Comparison of minimally invasive decompression and combined minimally invasive decompression and fusion in patients with degenerative spondylolisthesis with instability. Reviewed

    Hayashi K, Toyoda H, Terai H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Ohyama S, Hori Y, Yabu A, Nakamura H

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   57   79 - 85   2018.11( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2018.08.032

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  • Spinopelvic Sagittal Alignment after Microendoscopic Laminotomy in Patients with Lumbar Degenerative Spondylolisthesis. Reviewed

    Dohzono S, Toyoda H, Hori Y, Takahashi S, Suzuki A, Terai H, Nakamura H

    Journal of neurological surgery. Part A, Central European neurosurgery   79 ( 6 )   479 - 485   2018.11( ISSN:2193-6315

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    DOI: 10.1055/s-0038-1666847

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  • RA腰椎病変を合併する腰部脊柱管狭窄症の手術成績 非RA患者とのMatched Case Control Study Reviewed

    山田 賢太郎, 鈴木 亨暢, 高橋 真治, 豊田 宏光, 星野 雅俊, 寺井 秀富, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   9 ( 6 )   1044 - 1048   2018.06( ISSN:1884-7137

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    関節リウマチ(RA)の腰椎病変にはすべり・側彎・椎体骨折が含まれるが、これらはいずれも非RA患者でもみられる。本研究はRA腰椎病変を合併する脊柱管狭窄症手術を行った15例と年齢・性別・病態・手術術式をmatchさせた非RA患者25例の術後成績を比較検討した。その結果、術前画像が同様のRA群/非RA群で臨床成績に差がなかったものの固定後隣接椎間障害・除圧後すべり増強がRAで多くみられる傾向にあった。(著者抄録)

  • RA腰椎病変を合併する腰部脊柱管狭窄症の手術成績 非RA患者とのMatched Case Control Study Reviewed

    山田 賢太郎, 鈴木 亨暢, 高橋 真治, 豊田 宏光, 星野 雅俊, 寺井 秀富, 中村 博亮

    Journal of Spine Research   9 ( 6 )   1044 - 1048   2018.06( ISSN:1884-7137

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    関節リウマチ(RA)の腰椎病変にはすべり・側彎・椎体骨折が含まれるが、これらはいずれも非RA患者でもみられる。本研究はRA腰椎病変を合併する脊柱管狭窄症手術を行った15例と年齢・性別・病態・手術術式をmatchさせた非RA患者25例の術後成績を比較検討した。その結果、術前画像が同様のRA群/非RA群で臨床成績に差がなかったものの固定後隣接椎間障害・除圧後すべり増強がRAで多くみられる傾向にあった。(著者抄録)

  • 予後不良因子を持つ骨粗鬆症性新鮮椎体骨折に対するBKPの有用性 多施設前向き介入研究(第1報) Reviewed

    星野 雅俊, 高橋 真治, 安田 宏之, 寺井 秀富, 渡辺 享永, 林 和憲, 辻尾 唯雄, 河野 浩, 鈴木 亨暢, 玉井 孝司, 大山 翔一朗, 豊田 宏光, 笹岡 隆一, 堂園 将, 兼松 文昭, 白 隆光, 高山 和士, 加藤 相勲, 堀 悠介, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   9 ( 5 )   959 - 964   2018.05( ISSN:1884-7137

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    予後不良因子(MRI・T2強調画像における高信号あるいは低信号広範)を持つ骨粗鬆症性新鮮椎体骨折に対するBKP早期介入の多施設単群前向き介入試験における中間解析では、BKP早期介入の45例は、同一の予後不良因子を持ち保存治療を受けた患者で性・年齢・骨折高位をマッチさせた45例との比較で、有意にADLの低下を防ぎ、QOLを回復させ、椎体変形を改善した。しかし隣接椎体骨折の発生は高率に認められた。(著者抄録)

  • <i>Candida</i> is a protractive factor of chronic oral ulcers among usual outpatients. Reviewed

    Terai H, Ueno T, Suwa Y, Omori M, Yamamoto K, Kasuya S

    The Japanese dental science review   54 ( 2 )   52 - 58   2018.05( ISSN:1882-7616

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    DOI: 10.1016/j.jdsr.2017.12.001

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  • 予後不良因子を持つ骨粗鬆症性新鮮椎体骨折に対するBKPの有用性 多施設前向き介入研究(第1報) Reviewed

    星野 雅俊, 高橋 真治, 安田 宏之, 寺井 秀富, 渡辺 享永, 林 和憲, 辻尾 唯雄, 河野 浩, 鈴木 亨暢, 玉井 孝司, 大山 翔一朗, 豊田 宏光, 笹岡 隆一, 堂園 将, 兼松 文昭, 白 隆光, 高山 和士, 加藤 相勲, 堀 悠介, 中村 博亮

    Journal of Spine Research   9 ( 5 )   959 - 964   2018.05( ISSN:1884-7137

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    予後不良因子(MRI・T2強調画像における高信号あるいは低信号広範)を持つ骨粗鬆症性新鮮椎体骨折に対するBKP早期介入の多施設単群前向き介入試験における中間解析では、BKP早期介入の45例は、同一の予後不良因子を持ち保存治療を受けた患者で性・年齢・骨折高位をマッチさせた45例との比較で、有意にADLの低下を防ぎ、QOLを回復させ、椎体変形を改善した。しかし隣接椎体骨折の発生は高率に認められた。(著者抄録)

  • 特集 アスリートの脊椎・脊髄障害-病態と早期復帰への工夫 スポーツ選手の腰椎椎間板ヘルニアに対する内視鏡下後方手術 Reviewed

    寺井 秀富, 金田 国一, 大嶺 俊充, 中村 博亮

    脊椎脊髄ジャーナル   31 ( 3 )   239 - 245   2018.03( ISSN:09144412

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    DOI: 10.11477/mf.5002200823

  • Validity and Reproducibility of Various Measurement Methods for Craniocervical Sagittal Balance Reviewed

    Tamai Koji, Suzuki Akinobu, Takahashi Shinji, Hoshino Masatoshi, Toyoda Hiromitsu, Hayashi Kazunori, Ohyama Shoichiro, Kishimura Yuichi, Onode Ema, Umano Masayuki, Terai Hidetomi, Nakamura Hiroaki

    CLINICAL SPINE SURGERY   31 ( 2 )   80 - 85   2018.03( ISSN:2380-0186

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    DOI: 10.1097/BSD.0000000000000590

  • Validity and Reproducibility of Various Measurement Methods for Craniocervical Sagittal Balance. Reviewed

    Tamai K, Suzuki A, Takahashi S, Hoshino M, Toyoda H, Hayashi K, Ohyama S, Kishimura Y, Onode E, Umano M, Terai H, Nakamura H

    Clinical spine surgery   31 ( 2 )   80 - 85   2018.03( ISSN:2380-0186

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    DOI: 10.1097/BSD.0000000000000617

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  • Validity and Reproducibility of Various Measurement Methods for Craniocervical Sagittal Balance. Reviewed

    Tamai K, Suzuki A, Takahashi S, Hoshino M, Toyoda H, Hayashi K, Ohyama S, Kishimura Y, Onode E, Umano M, Terai H, Nakamura H

    Clinical spine surgery   31 ( 2 )   80 - 85   2018.03( ISSN:2380-0186

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    DOI: 10.1097/BSD.0000000000000617

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  • 【アスリートの脊椎・脊髄障害-病態と早期復帰への工夫】スポーツ選手の腰椎椎間板ヘルニアに対する内視鏡下後方手術 Reviewed

    寺井 秀富, 金田 国一, 大嶺 俊充, 中村 博亮

    脊椎脊髄ジャーナル   31 ( 3 )   239 - 245   2018.03( ISSN:0914-4412

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    <文献概要>はじめに 腰椎椎間板ヘルニアに対する手術療法(椎間板摘出術)として,顕微鏡下椎間板ヘルニア摘出術(microscopic discectomy:MD)や内視鏡下椎間板ヘルニア摘出術(microendoscopic discectomy:MED),経皮的内視鏡下椎間板ヘルニア摘出術(percutaneous endoscopic lumbar discectomy:PELD)など,さまざまな低侵襲手術手技が確立している.一般患者におけるそれら低侵襲手術手技の成績は非常に良好であり,術式間で大きな差はないとされている5).しかし,アプローチやワーキングスペースの大きさなど各術式の特徴とそれらの手技に適するヘルニアのタイプについて知っておく必要がある.本稿では,アスリートの腰椎椎間板ヘルニアの手術に関して,どのような場合にMEDが適しているか,実際にMEDを行う際の注意点,MED術後のスポーツ復帰の状況などについて述べる.

  • ER Stress Signaling Promotes the Survival of Cancer "Persister Cells" Tolerant to EGFR Tyrosine Kinase Inhibitors. Reviewed

    Terai H, Kitajima S, Potter DS, Matsui Y, Quiceno LG, Chen T, Kim TJ, Rusan M, Thai TC, Piccioni F, Donovan KA, Kwiatkowski N, Hinohara K, Wei G, Gray NS, Fischer ES, Wong KK, Shimamura T, Letai A, Hammerman PS, Barbie DA

    Cancer research   78 ( 4 )   1044 - 1057   2018.02( ISSN:0008-5472

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    DOI: 10.1158/0008-5472.CAN-17-1904

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  • Diffuse idiopathic skeletal hyperostosis is associated with lumbar spinal stenosis requiring surgery. Reviewed

    Yamada K, Satoh S, Hashizume H, Yoshimura N, Kagotani R, Ishimoto Y, Abe Y, Toyoda H, Terai H, Masuda T, Muraki S, Nakamura H, Yoshida M

    Journal of bone and mineral metabolism   2018.01( ISSN:0914-8779

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    DOI: 10.1007/s00774-017-0901-0

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  • Differences in short-term clinical and radiological outcomes depending on timing of balloon kyphoplasty for painful osteoporotic vertebral fracture Reviewed

    Takahashi Shinji, Hoshino Masatoshi, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Tamai Koji, Watanabe Kyoei, Tsujio Tadao, Yasuda Hiroyuki, Kono Hiroshi, Sasaoka Ryuichi, Dohzono Sho, Hayashi Kazunori, Ohyama Shoichiro, Hori Yusuke, Nakamura Hiroaki

    JOURNAL OF ORTHOPAEDIC SCIENCE   23 ( 1 )   51 - 56   2018.01( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2017.09.019

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  • 有痛性骨粗鬆症性椎体骨折に対するバルーン後彎形成術の時期に応じた短期臨床的および放射線学的転帰の差(Differences in short-term clinical and radiological outcomes depending on timing of balloon kyphoplasty for painful osteoporotic vertebral fracture) Reviewed

    Takahashi Shinji, Hoshino Masatoshi, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Tamai Koji, Watanabe Kyoei, Tsujio Tadao, Yasuda Hiroyuki, Kono Hiroshi, Sasaoka Ryuichi, Dohzono Sho, Hayashi Kazunori, Ohyama Shoichiro, Hori Yusuke, Nakamura Hiroaki

    (公社)日本整形外科学会 Journal of Orthopaedic Science   23 ( 1 )   51 - 56   2018.01( ISSN:0949-2658

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    2012年1月-2016年1月にバルーン後彎形成術を受けた連続患者72例を対象とした多施設共同コホート研究を行った。患者を有痛性骨粗鬆症性椎体骨折(OVF)発症後の後彎形成術時期に応じた2群(早期群(2ヵ月以内):女性19名、男性8名、平均年齢79.9歳、晩期群(2ヵ月より後):女性31名、男性14名、平均年齢77.9歳)に分けて解析した。6ヵ月超継続して追跡した。晩期群では術前の骨折椎体の角運動と前方椎体高の圧迫が大きかった。年齢および術前転帰について調整した最終転帰では、早期群で晩期群よりも腰痛の視覚的アナログ尺度(VAS)スコアが低くなった。最終の相対前方椎体高および後彎角は、早期群で晩期群よりも大きく維持されたが、絶対差は有意ではなかった。

  • Differences in short-term clinical and radiological outcomes depending on timing of balloon kyphoplasty for painful osteoporotic vertebral fracture. Reviewed

    Takahashi S, Hoshino M, Terai H, Toyoda H, Suzuki A, Tamai K, Watanabe K, Tsujio T, Yasuda H, Kono H, Sasaoka R, Dohzono S, Hayashi K, Ohyama S, Hori Y, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   23 ( 1 )   51 - 56   2018.01( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2017.09.019

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  • 有痛性骨粗鬆症性椎体骨折に対するバルーン後彎形成術の時期に応じた短期臨床的および放射線学的転帰の差(Differences in short-term clinical and radiological outcomes depending on timing of balloon kyphoplasty for painful osteoporotic vertebral fracture) Reviewed

    Takahashi Shinji, Hoshino Masatoshi, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Tamai Koji, Watanabe Kyoei, Tsujio Tadao, Yasuda Hiroyuki, Kono Hiroshi, Sasaoka Ryuichi, Dohzono Sho, Hayashi Kazunori, Ohyama Shoichiro, Hori Yusuke, Nakamura Hiroaki

    Journal of Orthopaedic Science   23 ( 1 )   51 - 56   2018.01( ISSN:0949-2658

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    2012年1月-2016年1月にバルーン後彎形成術を受けた連続患者72例を対象とした多施設共同コホート研究を行った。患者を有痛性骨粗鬆症性椎体骨折(OVF)発症後の後彎形成術時期に応じた2群(早期群(2ヵ月以内):女性19名、男性8名、平均年齢79.9歳、晩期群(2ヵ月より後):女性31名、男性14名、平均年齢77.9歳)に分けて解析した。6ヵ月超継続して追跡した。晩期群では術前の骨折椎体の角運動と前方椎体高の圧迫が大きかった。年齢および術前転帰について調整した最終転帰では、早期群で晩期群よりも腰痛の視覚的アナログ尺度(VAS)スコアが低くなった。最終の相対前方椎体高および後彎角は、早期群で晩期群よりも大きく維持されたが、絶対差は有意ではなかった。

  • Surgical Treatment of a Patient with Prolonged Exacerbation of Hirayama Disease Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Tamura Akiko, Hayashi Kazunori, Terai Hidetomi, Nakamura Hiroaki

    一般社団法人 日本脊椎脊髄病学会 Spine Surgery and Related Research   2018

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    DOI: 10.22603/ssrr.2018-0037

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  • Risk Factors for Proximal Junctional Fracture following Fusion Surgery for Osteoporotic Vertebral Collapse with Delayed Neurological Deficits: A Retrospective Cohort Study of 403 Patients Reviewed

    Tamai Koji, Hirano Toru, Kaito Takashi, Yamashita Tomoya, Fujiwara Hiroyasu, Nagamoto Yukitaka, Matsuoka Yuji, Suzuki Hidekazu, Nishimura Hirosuke, Tagami Atsushi, Yamada Syuta, Terai Hidetomi, Adachi Shinji, Yoshii Toshitaka, Ushio Shuta, Harimaya Katsumi, Kawaguchi Kenichi, Yokoyama Nobuhiko, Oishi Hidekazu, Doi Toshiro, Kimura Atsushi, Inoue Hirokazu, Suzuki Akinobu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Nakano Atsushi, Sakai Daisuke, Nukaga Tadashi, Ikegami Shota, Shimizu Masayuki, Futatsugi Toshimasa, Ohtori Seiji, Nakamura Hiroaki, Furuya Takeo, Orita Sumihisa, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Kiyasu Katsuhito, Murakami Hideki, Yoshioka Katsuhito, Seki Shoji, Hongo Michio, Watanabe. Kei, Kakutani Kenichiro, Yurube Takashi, Aoki Yasuchika, Oshima Masashi, Takahata Masahiko, Iwata Akira, Endo Hirooki, Abe Tetsuya, Tsukanishi Toshinori, Nakanishi Kazuyoshi, Katsumi Keiichi, Watanabe Kota, Hikata Tomohiro, Suzuki Satoshi, Isogai Norihiro, Okada Eijiro, Funao Haruki, Ueda Seiji, Shiono Yuta, Nojiri Kenya, Hosogane Naobumi, Ohashi Masayuki, Ishii Ken, Shibuya Yohei, Izumi Tomohiro

    一般社団法人 日本脊椎脊髄病学会 Spine Surgery and Related Research   2018

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    <p><b>Introduction</b></p><p>Approximately 3% of osteoporotic vertebral fractures develop osteoporotic vertebral collapse (OVC) with neurological deficits, and such patients are recommended to be treated surgically. However, a proximal junctional fracture (PJFr) following surgery for OVC can be a serious concern. Therefore, the aim of this study is to identify the incidence and risk factors of PJFr following fusion surgery for OVC.</p><p><b>Methods</b></p><p>This study retrospectively analyzed registry data collected from facilities belonging to the Japan Association of Spine Surgeons with Ambition (JASA) in 2016. We retrospectively analyzed 403 patients who suffered neurological deficits due to OVC below T10 and underwent corrective surgery; only those followed up for ≥2 years were included. Potential risk factors related to the PJFr and their cut-off values were calculated using multivariate logistic regression analysis and receiver operating characteristic (ROC) analysis.</p><p><b>Results</b></p><p>Sixty-three patients (15.6%) suffered PJFr during the follow-up (mean 45.7 months). In multivariate analysis, the grade of osteoporosis (grade 2, 3: adjusted odds ratio (aOR) 2.92; p=0.001) and lower instrumented vertebra (LIV) level (sacrum: aOR 6.75; p=0.003) were independent factors. ROC analysis demonstrated that lumbar bone mineral density (BMD) was a predictive factor (area under curve: 0.72, p=0.035) with optimal cut-off value of 0.61 g/cm² (sensitivity, 76.5%; specificity, 58.3%), but that of the hip was not (p=0.228).</p><p><b>Conclusion</b></p><p>PJFr was found in 16% cases within 4 years after surgery; independent risk factors were severe osteoporosis and extended fusion to the sacrum. The lumbar BMD with cut-off value 0.61 g/cm² may potentially predict PJFr. Our findings can help surgeons select perioperative adjuvant therapy, as well as a surgical strategy to prevent PJFr following surgery.</p>

    DOI: 10.22603/ssrr.2018-0068

    CiNii Article

  • Impact of Hemodialysis on Surgical Outcomes and Mortality Rate After Lumbar Spine Surgery: A Matched Cohort Study Reviewed

    Hori Yusuke, Nakamura Hiroaki, Takahashi Shinji, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Suzuki Akinobu, Hayashi Kazunori, Tamai Koji, Ohyama Shoichiro

    一般社団法人 日本脊椎脊髄病学会 Spine Surgery and Related Research   2018

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    <p><b>Introduction: </b>Despite ongoing improvements in both dialysis and surgical techniques, spinal surgery in patients undergoing hemodialysis (HD) is a challenge to surgeons because of the high mortality rate. However, no previous studies have examined clinical outcomes after lumbar surgery in HD patients. The purpose of this study is to compare clinical outcomes and complication rates after lumbar spinal surgery in patients with or without hemodialysis.</p><p><b>Methods:</b> This retrospective, matched cohort study was conducted to compare surgical outcomes between HD vs non-HD patients who underwent lumbar surgery at our hospital. Controls were individually matched to cases at a ratio of 1:2. Clinical outcomes, complications, and mortality rates were compared between the two groups.</p><p><b>Results: </b>Twenty-nine patients in the HD group and 57 in the non-HD group were included in the current study. Five patients in the HD group died during the follow-up period, whereas no patients died in the non-HD group (mortality rate, 17.2% vs. 0%, <i>P</i> = 0.003). Japanese Orthopaedic Association (JOA) scores were significantly less improved in the HD group than in the non-HD group (11.9 vs. 14.2 preoperatively, <i>P</i> = 0.001; 19.9 vs. 25.1 at final follow-up, <i>P</i> < 0.001). Five patients underwent repeat surgery in the HD group, which was significantly higher than the non-HD group (17.2% vs. 3.5%, <i>P</i> = 0.041).</p><p><b>Conclusions:</b> The current study indicates that patients undergoing HD had poor outcomes after lumbar spinal surgery. Moreover, 5 of 29 patients died within a mean 2.4-years follow-up. The indications for lumbar spine surgery in HD patients must be carefully considered because of poor surgical outcomes and high mortality rate.</p>

    DOI: 10.22603/ssrr.2018-0025

    CiNii Article

  • Difference of clinical course between cases with bone union and those with delayed union following osteoporotic vertebral fractures Reviewed

    Yasuda Hiroyuki, Hoshino Masatoshi, Tsujio Tadao, Terai Hidetomi, Namikawa Takashi, Kato Minori, Matsumura Akira, Suzuki Akinobu, Takayama Kazushi, Takahashi Shinji, Nakamura Hiroaki

    ARCHIVES OF OSTEOPOROSIS   13 ( 1 )   3   2017.12( ISSN:1862-3522

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    DOI: 10.1007/s11657-017-0411-7

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  • Difference of clinical course between cases with bone union and those with delayed union following osteoporotic vertebral fractures. Reviewed

    Yasuda H, Hoshino M, Tsujio T, Terai H, Namikawa T, Kato M, Matsumura A, Suzuki A, Takayama K, Takahashi S, Nakamura H

    Archives of osteoporosis   13 ( 1 )   3   2017.12( ISSN:1862-3522

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    DOI: 10.1007/s11657-017-0411-7

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  • ヒト頸椎黄色靱帯の解剖学的解析 付着、被覆、横方向の広がりに関する特記事項(Anatomical analysis of human ligamentum flavum in the cervical spine: Special consideration to the attachments, coverage, and lateral extent) Reviewed

    Rahmani Mohammad Suhrab, Terai Hidetomi, Akhgar Javid, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Tamai Koji, Ahmadi Sayed Abdullah, Hayashi Kazunori, Takahashi Shinji, Nakamura Hiroaki

    (公社)日本整形外科学会 Journal of Orthopaedic Science   22 ( 6 )   994 - 1000   2017.11( ISSN:0949-2658

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    ヒト頸椎黄色靱帯(LF)の寸法、付着部、被覆範囲、LFと神経孔または椎間関節との関連性を検討した。ホルマリン固定死体15体(男性7体、女性8体、平均死亡時年齢83歳)から全脊柱を一塊として摘出し、椎弓根基部で2つに切離した。C2-C3〜C7-T1のLF90本を背側から測定した後、鉄材含有造影剤を塗布してCT撮影を行った。CT画像データから3次元CT画像を構築し、腰椎後方視認時の黄色靱帯の位置や、黄色靱帯と椎弓峡部、椎間間隙との正確な位置関係を計測した。LF高はC2-C3からC7-T1にかけて次第に長くなり、各レベルで内側部から外側部にかけて次第に縮小していた。LF幅およびLF厚は、頭側端から尾側端まで比較的一定であった。頸椎椎間関節の頭側端は平均4.6±0.7mmのLFで被覆されていたが、頸椎神経孔へのLFの進入はみられなかった。

  • Restrictions of cervical flexion after laminoplasty increase in the mechanical stress at the occipitocervical junction in non-rheumatoid arthritis patients Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Takahashi Shinji, Suzuki Akinobu, Terai Hidetomi, Nakamura Hiroaki

    JOURNAL OF CLINICAL NEUROSCIENCE   45   187 - 192   2017.11( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2017.06.001

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  • Anatomical analysis of human ligamentum flavum in the cervical spine: Special consideration to the attachments, coverage, and lateral extent Reviewed

    Rahmani Mohammad Suhrab, Terai Hidetomi, Akhgar Javid, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Tamai Koji, Ahmadi Sayed Abdullah, Hayashi Kazunori, Takahashi Shinji, Nakamura Hiroaki

    JOURNAL OF ORTHOPAEDIC SCIENCE   22 ( 6 )   994 - 1000   2017.11( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2017.07.008

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  • Restrictions of cervical flexion after laminoplasty increase in the mechanical stress at the occipitocervical junction in non-rheumatoid arthritis patients. Reviewed

    Dohzono S, Toyoda H, Takahashi S, Suzuki A, Terai H, Nakamura H

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   45   187 - 192   2017.11( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2017.06.001

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  • Anatomical analysis of human ligamentum flavum in the cervical spine: Special consideration to the attachments, coverage, and lateral extent. Reviewed

    Rahmani MS, Terai H, Akhgar J, Suzuki A, Toyoda H, Hoshino M, Tamai K, Ahmadi SA, Hayashi K, Takahashi S, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   22 ( 6 )   994 - 1000   2017.11( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2017.07.008

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  • ヒト頸椎黄色靱帯の解剖学的解析 付着、被覆、横方向の広がりに関する特記事項(Anatomical analysis of human ligamentum flavum in the cervical spine: Special consideration to the attachments, coverage, and lateral extent) Reviewed

    Rahmani Mohammad Suhrab, Terai Hidetomi, Akhgar Javid, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Tamai Koji, Ahmadi Sayed Abdullah, Hayashi Kazunori, Takahashi Shinji, Nakamura Hiroaki

    Journal of Orthopaedic Science   22 ( 6 )   994 - 1000   2017.11( ISSN:0949-2658

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    ヒト頸椎黄色靱帯(LF)の寸法、付着部、被覆範囲、LFと神経孔または椎間関節との関連性を検討した。ホルマリン固定死体15体(男性7体、女性8体、平均死亡時年齢83歳)から全脊柱を一塊として摘出し、椎弓根基部で2つに切離した。C2-C3〜C7-T1のLF90本を背側から測定した後、鉄材含有造影剤を塗布してCT撮影を行った。CT画像データから3次元CT画像を構築し、腰椎後方視認時の黄色靱帯の位置や、黄色靱帯と椎弓峡部、椎間間隙との正確な位置関係を計測した。LF高はC2-C3からC7-T1にかけて次第に長くなり、各レベルで内側部から外側部にかけて次第に縮小していた。LF幅およびLF厚は、頭側端から尾側端まで比較的一定であった。頸椎椎間関節の頭側端は平均4.6±0.7mmのLFで被覆されていたが、頸椎神経孔へのLFの進入はみられなかった。

  • Mechanical stress induces elastic fibre disruption and cartilage matrix increase in ligamentum flavum Reviewed

    Hayashi Kazunori, Suzuki Akinobu, Ahmadi Sayed Abdullah, Terai Hidetomi, Yamada Kentaro, Hoshino Masatoshi, Toyoda Hiromitsu, Takahashi Shinji, Tamai Koji, Ohyama Shoichiro, Javid Akgar, Rahmani Mohammad Suhrab, Hasib Maruf Mohammad, Nakamura Hiroaki

    SCIENTIFIC REPORTS   7 ( 1 )   13092   2017.10( ISSN:2045-2322

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    DOI: 10.1038/s41598-017-13360-w

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  • Mechanical stress induces elastic fibre disruption and cartilage matrix increase in ligamentum flavum. Reviewed

    Hayashi K, Suzuki A, Abdullah Ahmadi S, Terai H, Yamada K, Hoshino M, Toyoda H, Takahashi S, Tamai K, Ohyama S, Javid A, Suhrab Rahmani M, Hasib MM, Nakamura H

    Scientific reports   7 ( 1 )   13092   2017.10

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    DOI: 10.1038/s41598-017-13360-w

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  • 特集 高齢者(75歳以上)の運動器変性疾患に対する治療 脊椎の変性疾患に対する高齢者治療 頸椎変性疾患 高齢者のmidcervical central cord syndromeに対する頸椎前方固定術 Reviewed

    寺井 秀富, 玉井 孝司, 中村 博亮

    別冊整形外科   1 ( 72 )   78 - 84   2017.10( ISSN:02871645

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    DOI: 10.15106/j04037.2018088649

  • Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study Reviewed

    Kobayashi Kazuyoshi, Imagama Shiro, Ando Kei, Ishiguro Naoki, Yamashita Masaomi, Eguchi Yawara, Matsumoto Morio, Ishii Ken, Hikata Tomohiro, Seki Shoji, Terai Hidetomi, Suzuki Akinobu, Tamai Koji, Aramomi Masaaki, Ishikawa Tetsuhiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Yamada Kei, Hongo Michio, Nishimura Hirosuke, Suzuki Hidekazu, Nakano Atsushi, Watanabe Kazuyuki, Chikuda Hirotaka, Ohya Junichi, Aoki Yasuchika, Shimizu Masayuki, Futatsugi Toshimasa, Mukaiyama Keijiro, Hasegawa Masaichi, Kiyasu Katsuhito, Iizuka Haku, Iizuka Yoichi, Kobayashi Ryoichi, Nishida Kotaro, Kakutani Kenichiro, Nakajima Hideaki, Murakami Hideki, Demura Satoru, Kato Satoshi, Yoshioka Katsuhito, Namikawa Takashi, Watanabe Kei, Nakanishi Kazuyoshi, Nakagawa Yukihiro, Yoshimoto Mitsunori, Fujiwara Hiroyasu, Nishida Norihiro, Imajo Yasuaki, Yamazaki Masashi, Sakane Masataka, Abe Tetsuya, Fujii Kengo, Kaito Takashi, Furuya Takeo, Orita Sumihisa, Ohtori Seiji

    GLOBAL SPINE JOURNAL   7 ( 7 )   636 - 641   2017.10( ISSN:2192-5682

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    DOI: 10.1177/2192568217716144

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  • 80歳以上の患者における頸部手術に関連した合併症の危険因子(Risk factors of cervical surgery related complications in patients older than 80 years) Reviewed

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki, Yamashita Masaomi, Eguchi Yawara, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Matsumoto Morio, Ishii Ken, Hikata Tomohiro, Seki Shoji, Aramomi Masaaki, Ishikawa Tetsuhiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Yamada Kei, Hongo Michio, Endo Kenji, Suzuki Hidekazu, Nakano Atsushi, Watanabe Kazuyuki, Ohya Junichi, Chikuda Hirotaka, Aoki Yasuchika, Shimizu Masayuki, Futatsugi Toshimasa, Mukaiyama Keijiro, Hasegawa Masaichi, Kiyasu Katsuhito, Iizuka Haku, Nishida Kotaro, Kakutani Kenichiro, Nakajima Hideaki, Murakami Hideki, Demura Satoru, Kato Satoshi, Yoshioka Katsuhito, Namikawa Takashi, Watanabe Kei, Nakanishi Kazuyoshi, Nakagawa Yukihiro, Yoshimoto Mitsunori, Fujiwara Hiroyasu, Nishida Norihiro, Sakane Masataka, Yamazaki Masashi, Kaito Takashi, Furuya Takeo, Orita Sumihisa, Ohtori Seiji

    (一社)日本脊椎脊髄病学会 Spine Surgery and Related Research   1 ( 4 )   179 - 184   2017.10

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    80歳以上の高齢患者に頸部手術を施行する場合における手術合併症の危険因子を同定するため、多施設の登録症例データを後ろ向きに解析した。35施設にてdegenerative cervical myelopathyと診断され頸部手術を施行された80歳以上患者の登録症例66例(女性35例、年齢80〜91歳)の診療録を解析した。全合併症発生例は21例(32%)で、そのうち重大な合併症は7例(11%)、軽度の合併症は14例(21%)であった。年齢調整済みの多重ロジスティック回帰分析の結果、全合併症の発生に関する有意な危険因子として術前の脳血管障害の存在が、また重大な合併症の発生に関する有意な危険因子として癌の既往歴の存在が、それぞれ同定された。年齢、糖尿病の存在、診断疾患、の各因子は合併症の有意な予測因子とは認められなかった。

  • Complications Associated With Spine Surgery in Patients Aged 80 Years or Older: Japan Association of Spine Surgeons with Ambition (JASA) Multicenter Study. Reviewed

    Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Nishimura H, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S

    Global spine journal   7 ( 7 )   636 - 641   2017.10( ISSN:2192-5682

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    DOI: 10.1177/2192568217716144

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  • 80歳以上の患者における頸部手術に関連した合併症の危険因子(Risk factors of cervical surgery related complications in patients older than 80 years) Reviewed

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki, Yamashita Masaomi, Eguchi Yawara, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Matsumoto Morio, Ishii Ken, Hikata Tomohiro, Seki Shoji, Aramomi Masaaki, Ishikawa Tetsuhiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Yamada Kei, Hongo Michio, Endo Kenji, Suzuki Hidekazu, Nakano Atsushi, Watanabe Kazuyuki, Ohya Junichi, Chikuda Hirotaka, Aoki Yasuchika, Shimizu Masayuki, Futatsugi Toshimasa, Mukaiyama Keijiro, Hasegawa Masaichi, Kiyasu Katsuhito, Iizuka Haku, Nishida Kotaro, Kakutani Kenichiro, Nakajima Hideaki, Murakami Hideki, Demura Satoru, Kato Satoshi, Yoshioka Katsuhito, Namikawa Takashi, Watanabe Kei, Nakanishi Kazuyoshi, Nakagawa Yukihiro, Yoshimoto Mitsunori, Fujiwara Hiroyasu, Nishida Norihiro, Sakane Masataka, Yamazaki Masashi, Kaito Takashi, Furuya Takeo, Orita Sumihisa, Ohtori Seiji

    Spine Surgery and Related Research   1 ( 4 )   179 - 184   2017.10

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    80歳以上の高齢患者に頸部手術を施行する場合における手術合併症の危険因子を同定するため、多施設の登録症例データを後ろ向きに解析した。35施設にてdegenerative cervical myelopathyと診断され頸部手術を施行された80歳以上患者の登録症例66例(女性35例、年齢80〜91歳)の診療録を解析した。全合併症発生例は21例(32%)で、そのうち重大な合併症は7例(11%)、軽度の合併症は14例(21%)であった。年齢調整済みの多重ロジスティック回帰分析の結果、全合併症の発生に関する有意な危険因子として術前の脳血管障害の存在が、また重大な合併症の発生に関する有意な危険因子として癌の既往歴の存在が、それぞれ同定された。年齢、糖尿病の存在、診断疾患、の各因子は合併症の有意な予測因子とは認められなかった。

  • 【高齢者(75歳以上)の運動器変性疾患に対する治療】脊椎の変性疾患に対する高齢者治療 頸椎変性疾患 高齢者のmidcervical central cord syndromeに対する頸椎前方固定術 Reviewed

    寺井 秀富, 玉井 孝司, 中村 博亮

    別冊整形外科   ( 72 )   78 - 84   2017.10( ISSN:0287-1645

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  • Risk factors for cognitive decline following osteoporotic vertebral fractures: A multicenter cohort study Reviewed

    Takahashi Shinji, Hoshino Masatoshi, Tsujio Tadao, Terai Hidetomi, Suzuki Akinobu, Namikawa Takashi, Kato Minori, Matsumura Akira, Takayama Kazushi, Nakamura Hiroaki

    JOURNAL OF ORTHOPAEDIC SCIENCE   22 ( 5 )   834 - 839   2017.09( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2017.04.008

    PubMed

  • 骨粗鬆症性椎体骨折後の認知機能低下の危険因子 多施設共同コホート研究(Risk factors for cognitive decline following osteoporotic vertebral fractures: A multicenter cohort study) Reviewed

    Takahashi Shinji, Hoshino Masatoshi, Tsujio Tadao, Terai Hidetomi, Suzuki Akinobu, Namikawa Takashi, Kato Minori, Matsumura Akira, Takayama Kazushi, Nakamura Hiroaki

    (公社)日本整形外科学会 Journal of Orthopaedic Science   22 ( 5 )   834 - 839   2017.09( ISSN:0949-2658

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    骨粗鬆症性椎体骨折患者339例(男性58例、女性281例)を対象に、認知機能の変化、認知機能低下の危険因子を前向き多施設共同コホート研究によって検討した。ミニメンタルステート検査(MMSE)を実施して認知機能を評価し、認知機能低下の危険因子として病歴、X線学的所見、ADLについて検討した。5例に外科術を施行し、234例が急性期に数日間の入院、109例が外来治療を受けていた。コルセットの装着は305例であった。ベースライン時、認知障害なしが283例(83.5%)、軽度認知障害が56例(16.5%)であり、6ヵ月後のフォローアップ時に認知機能低下をきたしたのは26例(7.7%)であった。認知機能低下群と非低下群に関して、年齢、性別、骨密度、教育レベル、喫煙習慣、スポーツ習慣に差はなく、ベースライン時のMMSEスコアにも差は認められなかった。病歴については、糖尿病患者の比率が認知機能低下群に高い傾向にあった。また、認知機能低下のオッズ比の上昇は骨折遷延治癒、6ヵ月後のADL低下と関連していた。骨粗鬆症性椎体骨折患者において、骨折遷延治癒とADL低下が認知機能低下の危険因子と成りうることが示された。

  • Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study Reviewed

    Kobayashi Kazuyoshi, Imagama Shiro, Ando Kei, Ishiguro Naoki, Yamashita Masaomi, Eguchi Yawara, Matsumoto Morio, Ishii Ken, Hikata Tomohiro, Seki Shoji, Terai Hidetomi, Suzuki Akinobu, Tamai Koji, Aramomi Masaaki, Ishikawa Tetsuhiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Yamada Kei, Hongo Michio, Matsuoka Yuji, Suzuki Hidekazu, Nakano Atsushi, Watanabe Kazuyuki, Chikuda Hirotaka, Ohya Junichi, Aoki Yasuchika, Shimizu Masayuki, Futatsugi Toshimasa, Mukaiyama Keijiro, Hasegawa Masaichi, Kiyasu Katsuhito, Iizuka Haku, Iizuka Yoichi, Kobayashi Ryoichi, Nishida Kotaro, Kakutani Kenichiro, Nakajima Hideaki, Murakami Hideki, Demura Satoru, Kato Satoshi, Yoshioka Katsuhito, Namikawa Takashi, Watanabe Kei, Nakanishi Kazuyoshi, Nakagawa Yukihiro, Yoshimoto Mitsunori, Fujiwara Hiroyasu, Nishida Norihiro, Imajo Yasuaki, Yamazaki Masashi, Sakane Masataka, Abe Tetsuya, Fujii Kengo, Kaito Takashi, Furuya Takeo, Orita Sumihisa, Ohtori Seiji

    GLOBAL SPINE JOURNAL   7 ( 6 )   560 - 566   2017.09( ISSN:2192-5682

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    DOI: 10.1177/2192568217700115

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  • Risk factors for cognitive decline following osteoporotic vertebral fractures: A multicenter cohort study. Reviewed

    Takahashi S, Hoshino M, Tsujio T, Terai H, Suzuki A, Namikawa T, Kato M, Matsumura A, Takayama K, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   22 ( 5 )   834 - 839   2017.09( ISSN:0949-2658

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jos.2017.04.008

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  • 骨粗鬆症性椎体骨折後の認知機能低下の危険因子 多施設共同コホート研究(Risk factors for cognitive decline following osteoporotic vertebral fractures: A multicenter cohort study) Reviewed

    Takahashi Shinji, Hoshino Masatoshi, Tsujio Tadao, Terai Hidetomi, Suzuki Akinobu, Namikawa Takashi, Kato Minori, Matsumura Akira, Takayama Kazushi, Nakamura Hiroaki

    Journal of Orthopaedic Science   22 ( 5 )   834 - 839   2017.09( ISSN:0949-2658

     More details

    Publishing type:Research paper (scientific journal)  

    骨粗鬆症性椎体骨折患者339例(男性58例、女性281例)を対象に、認知機能の変化、認知機能低下の危険因子を前向き多施設共同コホート研究によって検討した。ミニメンタルステート検査(MMSE)を実施して認知機能を評価し、認知機能低下の危険因子として病歴、X線学的所見、ADLについて検討した。5例に外科術を施行し、234例が急性期に数日間の入院、109例が外来治療を受けていた。コルセットの装着は305例であった。ベースライン時、認知障害なしが283例(83.5%)、軽度認知障害が56例(16.5%)であり、6ヵ月後のフォローアップ時に認知機能低下をきたしたのは26例(7.7%)であった。認知機能低下群と非低下群に関して、年齢、性別、骨密度、教育レベル、喫煙習慣、スポーツ習慣に差はなく、ベースライン時のMMSEスコアにも差は認められなかった。病歴については、糖尿病患者の比率が認知機能低下群に高い傾向にあった。また、認知機能低下のオッズ比の上昇は骨折遷延治癒、6ヵ月後のADL低下と関連していた。骨粗鬆症性椎体骨折患者において、骨折遷延治癒とADL低下が認知機能低下の危険因子と成りうることが示された。

  • Risk Factors for Delirium After Spine Surgery in Extremely Elderly Patients Aged 80 Years or Older and Review of the Literature: Japan Association of Spine Surgeons with Ambition Multicenter Study. Reviewed

    Kobayashi K, Imagama S, Ando K, Ishiguro N, Yamashita M, Eguchi Y, Matsumoto M, Ishii K, Hikata T, Seki S, Terai H, Suzuki A, Tamai K, Aramomi M, Ishikawa T, Kimura A, Inoue H, Inoue G, Miyagi M, Saito W, Yamada K, Hongo M, Matsuoka Y, Suzuki H, Nakano A, Watanabe K, Chikuda H, Ohya J, Aoki Y, Shimizu M, Futatsugi T, Mukaiyama K, Hasegawa M, Kiyasu K, Iizuka H, Iizuka Y, Kobayashi R, Nishida K, Kakutani K, Nakajima H, Murakami H, Demura S, Kato S, Yoshioka K, Namikawa T, Watanabe K, Nakanishi K, Nakagawa Y, Yoshimoto M, Fujiwara H, Nishida N, Imajo Y, Yamazaki M, Sakane M, Abe T, Fujii K, Kaito T, Furuya T, Orita S, Ohtori S

    Global spine journal   7 ( 6 )   560 - 566   2017.09( ISSN:2192-5682

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    DOI: 10.1177/2192568217700115

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  • Anterior Cervical Discectomy and Fusion Provides Better Surgical Outcomes Than Posterior Laminoplasty in Elderly Patients With C3-4 Level Myelopathy Reviewed

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Takahashi Shinji, Hayashi Kazunori, Ohyama Shoichiro, Nakamura Hiroaki

    SPINE   42 ( 8 )   548 - 555   2017.04( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000001874

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  • Incidence of Pleural Fluid and Its Associated Risk Factors After Posterior Spinal Fusion in Patients With Adolescent Idiopathic Scoliosis Reviewed

    Hayashi Kazunori, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Hoshino Masatoshi, Tamai Koji, Ohyama Shoichiro, Nakamura Hiroaki

    SPINE   42 ( 8 )   603 - 609   2017.04( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000001861

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  • Anterior Cervical Discectomy and Fusion Provides Better Surgical Outcomes Than Posterior Laminoplasty in Elderly Patients With C3-4 Level Myelopathy. Reviewed

    Tamai K, Terai H, Suzuki A, Toyoda H, Hoshino M, Takahashi S, Hayashi K, Ohyama S, Nakamura H

    Spine   42 ( 8 )   548 - 555   2017.04( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000001874

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  • Incidence of Pleural Fluid and Its Associated Risk Factors After Posterior Spinal Fusion in Patients With Adolescent Idiopathic Scoliosis. Reviewed

    Hayashi K, Terai H, Toyoda H, Suzuki A, Hoshino M, Tamai K, Ohyama S, Nakamura H

    Spine   42 ( 8 )   603 - 609   2017.04( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000001861

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  • Clinical and Radiological Outcomes after Microscopic Bilateral Decompression via a Unilateral Approach for Degenerative Lumbar Disease: Minimum 5-Year Follow-Up Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Matsumura Akira, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki

    ASIAN SPINE JOURNAL   11 ( 2 )   285 - 293   2017.04( ISSN:1976-1902

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    DOI: 10.4184/asj.2017.11.2.285

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  • Cervical lordotic alignment following posterior spinal fusion for adolescent idiopathic scoliosis: reciprocal changes and risk factors for malalignment Reviewed

    Hayashi Kazunori, Toyoda Hiromitsu, Terai Hidetomi, Suzuki Akinobu, Hoshino Masatoshi, Tamai Koji, Ohyama Shoichiro, Nakamura Hiroaki

    JOURNAL OF NEUROSURGERY-PEDIATRICS   19 ( 4 )   440 - 447   2017.04( ISSN:1933-0707

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    DOI: 10.3171/2016.9.PEDS16298

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  • Clinical and Radiological Outcomes after Microscopic Bilateral Decompression via a Unilateral Approach for Degenerative Lumbar Disease: Minimum 5-Year Follow-Up. Reviewed

    Dohzono S, Toyoda H, Matsumura A, Terai H, Suzuki A, Nakamura H

    Asian spine journal   11 ( 2 )   285 - 293   2017.04( ISSN:1976-1902

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.4184/asj.2017.11.2.285

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  • Cervical lordotic alignment following posterior spinal fusion for adolescent idiopathic scoliosis: reciprocal changes and risk factors for malalignment. Reviewed

    Hayashi K, Toyoda H, Terai H, Suzuki A, Hoshino M, Tamai K, Ohyama S, Nakamura H

    Journal of neurosurgery. Pediatrics   19 ( 4 )   440 - 447   2017.04( ISSN:1933-0707

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    DOI: 10.3171/2016.9.PEDS16298

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  • Anatomical analysis of the relation between human ligamentum flavum and posterior spinal bony prominence Reviewed

    Akhgar Javid, Terai Hidetomi, Rahmani Mohammad Suhrab, Tamai Koji, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Ikebuchi Mitsuhiko, Ahmadi Sayed Abdullah, Hayashi Kazunori, Nakamura Hiroaki

    JOURNAL OF ORTHOPAEDIC SCIENCE   22 ( 2 )   260 - 265   2017.03( ISSN:0949-2658

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    DOI: 10.1016/j.jos.2016.11.020

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  • ヒトの黄色靱帯と脊椎後方骨性隆起の関連についての解剖学的解析(Anatomical analysis of the relation between human ligamentum flavum and posterior spinal bony prominence) Reviewed

    Akhgar Javid, Terai Hidetomi, Rahmani Mohammad Suhrab, Tamai Koji, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Ikebuchi Mitsuhiko, Ahmadi Sayed Abdullah, Hayashi Kazunori, Nakamura Hiroaki

    (公社)日本整形外科学会 Journal of Orthopaedic Science   22 ( 2 )   260 - 265   2017.03( ISSN:0949-2658

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    骨性隆起と黄色靱帯との正確な位置関係を明らかにした。20体のホルマリン固定屍体から脊柱を離断した後に椎弓根基部にて椎弓根を切離し、椎弓と黄色靱帯を取り出した。黄色靱帯と椎弓の位置関係を計測した後、CT撮影を行った。CT撮影で得られたDICOMデータを用いて三次元CT画像解析装置により解析し、腰椎を後方からみた場合の黄色靱帯の位置を視覚化した。また、黄色靱帯と脊椎後方骨性隆起との正確な位置関係を調べた。両側LFはV型であり、付随する椎弓の形に沿っていた。LFの形状は腰上部において変化が認められたが、L5-S1のLFの形状は他の位置のLFとは異なっており、L5-S1のLFは各例で多様であった。椎弓根の内側縁とLFの外側縁の平均幅は腰上部から腰下部にかけて拡大していた。正中部における層間の空間とLFの頭蓋境界との幅は徐々に拡大し、L1で8.2mm、L4で11.1mm、L5で9.3mmであった。コントラストLFおよび再構成CTを用いた解剖学的解析により、骨性隆起とLF境界との関連が明らかとなった。

  • Anatomical analysis of the relation between human ligamentum flavum and posterior spinal bony prominence. Reviewed

    Akhgar J, Terai H, Rahmani MS, Tamai K, Suzuki A, Toyoda H, Hoshino M, Ikebuchi M, Ahmadi SA, Hayashi K, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   22 ( 2 )   260 - 265   2017.03( ISSN:0949-2658

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jos.2016.11.020

    PubMed

  • ヒトの黄色靱帯と脊椎後方骨性隆起の関連についての解剖学的解析(Anatomical analysis of the relation between human ligamentum flavum and posterior spinal bony prominence) Reviewed

    Akhgar Javid, Terai Hidetomi, Rahmani Mohammad Suhrab, Tamai Koji, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Ikebuchi Mitsuhiko, Ahmadi Sayed Abdullah, Hayashi Kazunori, Nakamura Hiroaki

    Journal of Orthopaedic Science   22 ( 2 )   260 - 265   2017.03( ISSN:0949-2658

     More details

    Publishing type:Research paper (scientific journal)  

    骨性隆起と黄色靱帯との正確な位置関係を明らかにした。20体のホルマリン固定屍体から脊柱を離断した後に椎弓根基部にて椎弓根を切離し、椎弓と黄色靱帯を取り出した。黄色靱帯と椎弓の位置関係を計測した後、CT撮影を行った。CT撮影で得られたDICOMデータを用いて三次元CT画像解析装置により解析し、腰椎を後方からみた場合の黄色靱帯の位置を視覚化した。また、黄色靱帯と脊椎後方骨性隆起との正確な位置関係を調べた。両側LFはV型であり、付随する椎弓の形に沿っていた。LFの形状は腰上部において変化が認められたが、L5-S1のLFの形状は他の位置のLFとは異なっており、L5-S1のLFは各例で多様であった。椎弓根の内側縁とLFの外側縁の平均幅は腰上部から腰下部にかけて拡大していた。正中部における層間の空間とLFの頭蓋境界との幅は徐々に拡大し、L1で8.2mm、L4で11.1mm、L5で9.3mmであった。コントラストLFおよび再構成CTを用いた解剖学的解析により、骨性隆起とLF境界との関連が明らかとなった。

  • Chip-based quantum key distribution. Reviewed

    Sibson P, Erven C, Godfrey M, Miki S, Yamashita T, Fujiwara M, Sasaki M, Terai H, Tanner MG, Natarajan CM, Hadfield RH, O'Brien JL, Thompson MG

    Nature communications   8   13984   2017.02

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    DOI: 10.1038/ncomms13984

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  • Prevalence of Diffuse Idiopathic Skeletal Hyperostosis in Patients with Spinal Disorders Reviewed

    Toyoda Hiromitsu, Terai Hidetomi, Yamada Kentaro, Suzuki Akinobu, Dohzono Sho, Matsumoto Tomiya, Nakamura Hiroaki

    ASIAN SPINE JOURNAL   11 ( 1 )   63 - 70   2017.02( ISSN:1976-1902

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    DOI: 10.4184/asj.2017.11.1.63

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  • Prevalence of Diffuse Idiopathic Skeletal Hyperostosis in Patients with Spinal Disorders. Reviewed

    Toyoda H, Terai H, Yamada K, Suzuki A, Dohzono S, Matsumoto T, Nakamura H

    Asian spine journal   11 ( 1 )   63 - 70   2017.02( ISSN:1976-1902

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    DOI: 10.4184/asj.2017.11.1.63

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  • A Prospective Multicenter Study Using a Virtual 3 Fr Percutaneous Coronary Intervention System: The V3 Registry. Reviewed

    Yoshimachi F, Takagawa Y, Terai H, Takahashi A, Shimada Y, Katsuki T, Tohara S, Ueno H, Takada M, Shiode N, Yamada K, Kinoshita N, Honda T, Asano H, Takeshita S, Koiwa H, Shin T, Masutani M, Matsukage T, Saito S, Ikari Y, The V3 Registry Investigators.

    The Journal of invasive cardiology   29 ( 1 )   16 - 23   2017.01( ISSN:1042-3931

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  • Risk factors of cervical surgery related complications in patients older than 80 years Reviewed

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki, Yamashita Masaomi, Eguchi Yawara, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Matsumoto Morio, Ishii Ken, Hikata Tomohiro, Seki Shoji, Aramomi Masaaki, Ishikawa Tetsuhiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Yamada Kei, Hongo Michio, Endo Kenji, Suzuki Hidekazu, Nakano Atsushi, Watanabe Kazuyuki, Ohya Junichi, Chikuda Hirotaka, Aoki Yasuchika, Shimizu Masayuki, Futatsugi Toshimasa, Mukaiyama Keijiro, Hasegawa Masaichi, Kiyasu Katsuhito, Iizuka Haku, Nishida Kotaro, Kakutani Kenichiro, Nakajima Hideaki, Murakami Hideki, Demura Satoru, Kato Satoshi, Yoshioka Katsuhito, Namikawa Takashi, Watanabe Kei, Nakanishi Kazuyoshi, Nakagawa Yukihiro, Yoshimoto Mitsunori, Fujiwara Hiroyasu, Nishida Norihiro, Sakane Masataka, Yamazaki Masashi, Kaito Takashi, Furuya Takeo, Orita Sumihisa, Ohtori Seiji

    一般社団法人 日本脊椎脊髄病学会 Spine Surgery and Related Research   1 ( 4 )   179 - 184   2017

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    <p>Introduction: With an aging population, the proportion of patients aged ≥80 years requiring cervical surgery is increasing. Surgeons are concerned with the high incidence of complications in this population, because "age" itself has been reported as a strong risk factor for complications. However, it is still unknown which factors represent higher risk among these elderly patients. Therefore, this study was conducted to identify the risk factors related to surgical complications specific to elderly patients by analyzing the registry data of patients aged ≥80 years who underwent cervical surgery.</p><p>Methods: We retrospectively studied multicenter collected registry data using multivariate analysis. Sixty-six patients aged ≥80 years who underwent cervical surgery and were followed up for more than one year were included in this study. Preoperative patient demographic data, including comorbidities and postoperative complications, were collected from multicenter registry data. Complications were considered as major if they required invasive intervention, caused prolonged morbidity, or resulted in prolongation of hospital stay. Logistic regression analysis was performed to analyze the risk factors for complications. A <i>p</i>-value of <0.05 was considered as statistically significant.</p><p>Results: The total number of patients with complications was 21 (31.8%), with seven major (10.6%) and 14 minor (21.2%) complications. Multivariate logistic regression analysis, after adjusting for age, revealed two significant risk factors: preoperative cerebrovascular disorders (OR, 6.337; p=0.043) for overall complications and cancer history (OR, 8.168; p=0.021) for major complications. Age, presence of diabetes mellitus, and diagnosis were not significant predictive factors for complications in this study.</p><p>Conclusions: Preoperative cerebrovascular disorders and cancer history were risk factors for complications after cervical surgery in patients over 80 years old. Surgeons should pay attention to these specific risk factors before performing cervical surgery in elderly patients.</p>

    DOI: 10.22603/ssrr.1.2017-0002

    CiNii Article

  • Risk factors of cervical surgery related complications in patients older than 80 years

    Tamai Koji, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki, Yamashita Masaomi, Eguchi Yawara, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Matsumoto Morio, Ishii Ken, Hikata Tomohiro, Seki Shoji, Aramomi Masaaki, Ishikawa Tetsuhiro, Kimura Atsushi, Inoue Hirokazu, Inoue Gen, Miyagi Masayuki, Saito Wataru, Yamada Kei, Hongo Michio, Endo Kenji, Suzuki Hidekazu, Nakano Atsushi, Watanabe Kazuyuki, Ohya Junichi, Chikuda Hirotaka, Aoki Yasuchika, Shimizu Masayuki, Futatsugi Toshimasa, Mukaiyama Keijiro, Hasegawa Masaichi, Kiyasu Katsuhito, Iizuka Haku, Nishida Kotaro, Kakutani Kenichiro, Nakajima Hideaki, Murakami Hideki, Demura Satoru, Kato Satoshi, Yoshioka Katsuhito, Namikawa Takashi, Watanabe Kei, Nakanishi Kazuyoshi, Nakagawa Yukihiro, Yoshimoto Mitsunori, Fujiwara Hiroyasu, Nishida Norihiro, Sakane Masataka, Yamazaki Masashi, Kaito Takashi, Furuya Takeo, Orita Sumihisa, Ohtori Seiji

    Spine Surgery and Related Research   1 ( 4 )   179 - 184   2017( eISSN:2432261X

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    <p>Introduction: With an aging population, the proportion of patients aged ≥80 years requiring cervical surgery is increasing. Surgeons are concerned with the high incidence of complications in this population, because "age" itself has been reported as a strong risk factor for complications. However, it is still unknown which factors represent higher risk among these elderly patients. Therefore, this study was conducted to identify the risk factors related to surgical complications specific to elderly patients by analyzing the registry data of patients aged ≥80 years who underwent cervical surgery.</p><p>Methods: We retrospectively studied multicenter collected registry data using multivariate analysis. Sixty-six patients aged ≥80 years who underwent cervical surgery and were followed up for more than one year were included in this study. Preoperative patient demographic data, including comorbidities and postoperative complications, were collected from multicenter registry data. Complications were considered as major if they required invasive intervention, caused prolonged morbidity, or resulted in prolongation of hospital stay. Logistic regression analysis was performed to analyze the risk factors for complications. A <i>p</i>-value of <0.05 was considered as statistically significant.</p><p>Results: The total number of patients with complications was 21 (31.8%), with seven major (10.6%) and 14 minor (21.2%) complications. Multivariate logistic regression analysis, after adjusting for age, revealed two significant risk factors: preoperative cerebrovascular disorders (OR, 6.337; p=0.043) for overall complications and cancer history (OR, 8.168; p=0.021) for major complications. Age, presence of diabetes mellitus, and diagnosis were not significant predictive factors for complications in this study.</p><p>Conclusions: Preoperative cerebrovascular disorders and cancer history were risk factors for complications after cervical surgery in patients over 80 years old. Surgeons should pay attention to these specific risk factors before performing cervical surgery in elderly patients.</p>

    DOI: 10.22603/ssrr.1.2017-0002

    PubMed

    CiNii Article

  • Clinical Outcome of Cervical Laminoplasty and Postoperative Radiological Change for Cervical Myelopathy With Degenerative Spondylolisthesis Reviewed

    Suzuki Akinobu, Tamai Koji, Terai Hidetomi, Hoshino Masatoshi, Toyoda Hiromitsu, Takahashi Shinji, Hayashi Kazunori, Ohyama Shoichiro, Nakamura Hiroaki

    SPINE   41 ( 23 )   1808 - 1812   2016.12( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000001706

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  • Clinical Outcome of Cervical Laminoplasty and Postoperative Radiological Change for Cervical Myelopathy With Degenerative Spondylolisthesis. Reviewed

    Suzuki A, Tamai K, Terai H, Hoshino M, Toyoda H, Takahashi S, Hayashi K, Ohyama S, Nakamura H

    Spine   41 ( 23 )   1808 - 1812   2016.12( ISSN:0362-2436

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    DOI: 10.1097/BRS.0000000000001706

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  • Detection-dependent six-photon Holland-Burnett state interference. Reviewed

    Jin RB, Fujiwara M, Shimizu R, Collins RJ, Buller GS, Yamashita T, Miki S, Terai H, Takeoka M, Sasaki M

    Scientific reports   6   36914   2016.11

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    DOI: 10.1038/srep36914

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  • 咽頭部違和感で発見された頸椎巨大神経鞘腫の1例 Reviewed

    林 和憲, 豊田 宏光, 寺井 秀富, 星野 雅俊, 鈴木 亨暢, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   59 ( 6 )   1215 - 1216   2016.11( ISSN:0008-9443

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    16歳男。1ヵ月前より咽頭部違和感を自覚し、学校健診にて咽頭部腫瘤を指摘され、同時期より左上肢の脱力を自覚するようになった。喉頭内視鏡にて咽頭後壁、左側粘膜下に弾性硬の腫瘤を認め、各種画像所見よりEden分類type 3の頸椎砂時計腫と診断して摘出術を計画した。当科と耳鼻科との合同で前方後方進入を用いた切除術を施行し、病理診断は神経鞘腫であった。術後、一時的に右耳介後方C3領域に軽度の知覚低下を認めたが、術後1年の現在、知覚低下は改善し、筋力も術前MMT4からMMT5に回復した。

  • 咽頭部違和感で発見された頸椎巨大神経鞘腫の1例 Reviewed

    林 和憲, 豊田 宏光, 寺井 秀富, 星野 雅俊, 鈴木 亨暢, 中村 博亮

    中部日本整形外科災害外科学会雑誌   59 ( 6 )   1215 - 1216   2016.11( ISSN:0008-9443

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    16歳男。1ヵ月前より咽頭部違和感を自覚し、学校健診にて咽頭部腫瘤を指摘され、同時期より左上肢の脱力を自覚するようになった。喉頭内視鏡にて咽頭後壁、左側粘膜下に弾性硬の腫瘤を認め、各種画像所見よりEden分類type 3の頸椎砂時計腫と診断して摘出術を計画した。当科と耳鼻科との合同で前方後方進入を用いた切除術を施行し、病理診断は神経鞘腫であった。術後、一時的に右耳介後方C3領域に軽度の知覚低下を認めたが、術後1年の現在、知覚低下は改善し、筋力も術前MMT4からMMT5に回復した。

  • Laminar closure after expansive open-door laminoplasty: fixation methods and cervical alignments impact on the laminar closure and surgical outcomes Reviewed

    Tamai Koji, Suzuki Akinobu, Terai Hidetomi, Toyoda Hiromitsu, Hoshino Masatoshi, Nakamura Hiroaki

    SPINE JOURNAL   16 ( 9 )   1062 - 1069   2016.09( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2016.04.018

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  • 頸椎に発生した軟骨肉腫clear cell typeの1例 Reviewed

    小林 祐人, 鈴木 亨暢, 大山 翔一朗, 寺井 秀富, 星野 雅俊, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   59 ( 5 )   1089 - 1090   2016.09( ISSN:0008-9443

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    58歳女性。頸部痛を主訴に近医を受診、頸椎X線にてC3脊椎腫瘍と診断され、紹介となった。MRIではT1強調像にて低信号、T2強調像にて等信号を示し、ガドリニウム造影およびCTでC3全周性に広がる造影効果の強い腫瘍が認められた。CTガイド下針生検の結果、grade Iの軟骨肉腫(通常型)と診断され、右椎骨動脈塞栓術を施行後、後方・前方からの椎骨動脈合併腫瘍全摘出術を行った。病理組織学的にgrade IIの軟骨肉腫(clear cell type)と判明し、術後3ヵ月で良好な骨癒合が得られたが、術後1年で同部位に再発を認めた。再切除後の再発が懸念されたため、インプラント抜去およびセパレーションサージェリー後に陽子線治療を行ったところ、照射後3ヵ月の時点で腫瘍の増大はみられず、経過は良好である。

  • Laminar closure after expansive open-door laminoplasty: fixation methods and cervical alignments impact on the laminar closure and surgical outcomes. Reviewed

    Tamai K, Suzuki A, Terai H, Toyoda H, Hoshino M, Nakamura H

    The spine journal : official journal of the North American Spine Society   16 ( 9 )   1062 - 9   2016.09( ISSN:1529-9430

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    DOI: 10.1016/j.spinee.2016.04.018

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  • 頸椎に発生した軟骨肉腫clear cell typeの1例 Reviewed

    小林 祐人, 鈴木 亨暢, 大山 翔一朗, 寺井 秀富, 星野 雅俊, 中村 博亮

    中部日本整形外科災害外科学会雑誌   59 ( 5 )   1089 - 1090   2016.09( ISSN:0008-9443

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    58歳女性。頸部痛を主訴に近医を受診、頸椎X線にてC3脊椎腫瘍と診断され、紹介となった。MRIではT1強調像にて低信号、T2強調像にて等信号を示し、ガドリニウム造影およびCTでC3全周性に広がる造影効果の強い腫瘍が認められた。CTガイド下針生検の結果、grade Iの軟骨肉腫(通常型)と診断され、右椎骨動脈塞栓術を施行後、後方・前方からの椎骨動脈合併腫瘍全摘出術を行った。病理組織学的にgrade IIの軟骨肉腫(clear cell type)と判明し、術後3ヵ月で良好な骨癒合が得られたが、術後1年で同部位に再発を認めた。再切除後の再発が懸念されたため、インプラント抜去およびセパレーションサージェリー後に陽子線治療を行ったところ、照射後3ヵ月の時点で腫瘍の増大はみられず、経過は良好である。

  • Utility of Discography as a Preoperative Diagnostic Tool for Intradural Lumbar Disc Herniation Reviewed

    Matsumoto Tomiya, Toyoda Hiromitsu, Terai Hidetomi, Dohzono Sho, Hori Yusuke, Nakamura Hiroaki

    ASIAN SPINE JOURNAL   10 ( 4 )   771 - 775   2016.08( ISSN:1976-1902

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    DOI: 10.4184/asj.2016.10.4.771

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  • Far-out Syndromeに対する内視鏡下後方除圧術の治療成績 術後の疼痛、しびれ感に着目して Reviewed

    金田 国一, 島田 永和, 寺井 秀富

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   7 ( 8 )   1251 - 1255   2016.08( ISSN:1884-7137

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    Far-out syndromeと診断した45症例に対し内視鏡下後方除圧術を行い治療成績を調査した。JOAスコアの平均改善率は77%と良好であった。術後に下肢痛の再燃を2例、強いしびれの残存を5例、臀部痛の持続を1例に認めたがNSAIDs、トラマドール配合錠、プレガバリン投与により3ヵ月以内に症状は軽快した。本病態の診断には病態の認識と前額断MRI、3D-CTが不可欠であると考えられた。(著者抄録)

  • 転移性脊椎腫瘍に対するCTガイド局所麻酔下椎体形成術 当科での手技とその効果及び安全性 Reviewed

    鈴木 亨暢, 玉井 孝司, 寺井 秀富, 星野 雅俊, 豊田 宏光, 林 和憲, 大山 翔一郎, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   7 ( 8 )   1313 - 1318   2016.08( ISSN:1884-7137

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    本研究の目的は転移性脊椎腫瘍に対する椎体形成術の当科での手法を報告し、その効果と問題点を明らかにすることである。局所麻酔下にCT下で椎体形成術を4例に施行し、術前後の疼痛、ADL、合併症について調査した。術後疼痛は全例で改善し、3例でADLの改善が認められた。セメントの脊柱管への漏出が3例に認められたが、重篤な合併症は認めなかった。転移性脊椎腫瘍に対する局麻下椎体形成術は低侵襲で有効な治療法となり得る。(著者抄録)

  • 椎体骨折癒合不全に伴う神経根症 Reviewed

    玉井 孝司, 豊田 宏光, 鈴木 亨暢, 寺井 秀富, 星野 雅俊, 高橋 真治, 林 和憲, 大山 翔一朗, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   7 ( 8 )   1246 - 1250   2016.08( ISSN:1884-7137

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    骨粗鬆症性椎体骨折後癒合不全に起因する神経根症の頻度や推移を明らかにするため、椎体形成術を行った症例を後ろ向きに解析した。結果、椎体骨折後癒合不全の20%に根症状を伴っており、70%の症例で腰痛≦下肢痛であったが、90%の症例で罹患椎体単独の椎体形成術にて早期に根症状が消失していた。発症要因としては、静的因子である椎間孔狭窄などより、動的因子である椎体不安定性の関与が強い可能性が示唆された。(著者抄録)

  • [Dual process in large number estimation under uncertainty]. Reviewed

    Matsumuro M, Miwa K, Terai H, Yamada K

    Shinrigaku kenkyu : The Japanese journal of psychology   87 ( 3 )   229 - 39   2016.08( ISSN:0021-5236

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    DOI: 10.4992/jjpsy.87.14077

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  • Far-out Syndromeに対する内視鏡下後方除圧術の治療成績 術後の疼痛、しびれ感に着目して Reviewed

    金田 国一, 島田 永和, 寺井 秀富

    Journal of Spine Research   7 ( 8 )   1251 - 1255   2016.08( ISSN:1884-7137

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    Far-out syndromeと診断した45症例に対し内視鏡下後方除圧術を行い治療成績を調査した。JOAスコアの平均改善率は77%と良好であった。術後に下肢痛の再燃を2例、強いしびれの残存を5例、臀部痛の持続を1例に認めたがNSAIDs、トラマドール配合錠、プレガバリン投与により3ヵ月以内に症状は軽快した。本病態の診断には病態の認識と前額断MRI、3D-CTが不可欠であると考えられた。(著者抄録)

  • Utility of Discography as a Preoperative Diagnostic Tool for Intradural Lumbar Disc Herniation. Reviewed

    Matsumoto T, Toyoda H, Terai H, Dohzono S, Hori Y, Nakamura H

    Asian spine journal   10 ( 4 )   771 - 5   2016.08( ISSN:1976-1902

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    DOI: 10.4184/asj.2016.10.4.771

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  • 転移性脊椎腫瘍に対するCTガイド局所麻酔下椎体形成術 当科での手技とその効果及び安全性 Reviewed

    鈴木 亨暢, 玉井 孝司, 寺井 秀富, 星野 雅俊, 豊田 宏光, 林 和憲, 大山 翔一郎, 中村 博亮

    Journal of Spine Research   7 ( 8 )   1313 - 1318   2016.08( ISSN:1884-7137

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    本研究の目的は転移性脊椎腫瘍に対する椎体形成術の当科での手法を報告し、その効果と問題点を明らかにすることである。局所麻酔下にCT下で椎体形成術を4例に施行し、術前後の疼痛、ADL、合併症について調査した。術後疼痛は全例で改善し、3例でADLの改善が認められた。セメントの脊柱管への漏出が3例に認められたが、重篤な合併症は認めなかった。転移性脊椎腫瘍に対する局麻下椎体形成術は低侵襲で有効な治療法となり得る。(著者抄録)

  • 椎体骨折癒合不全に伴う神経根症 Reviewed

    玉井 孝司, 豊田 宏光, 鈴木 亨暢, 寺井 秀富, 星野 雅俊, 高橋 真治, 林 和憲, 大山 翔一朗, 中村 博亮

    Journal of Spine Research   7 ( 8 )   1246 - 1250   2016.08( ISSN:1884-7137

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    骨粗鬆症性椎体骨折後癒合不全に起因する神経根症の頻度や推移を明らかにするため、椎体形成術を行った症例を後ろ向きに解析した。結果、椎体骨折後癒合不全の20%に根症状を伴っており、70%の症例で腰痛≦下肢痛であったが、90%の症例で罹患椎体単独の椎体形成術にて早期に根症状が消失していた。発症要因としては、静的因子である椎間孔狭窄などより、動的因子である椎体不安定性の関与が強い可能性が示唆された。(著者抄録)

  • Factors associated with improvement in sagittal spinal alignment after microendoscopic laminotomy in patients with lumbar spinal canal stenosis Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Takahashi Shinji, Matsumoto Tomiya, Suzuki Akinobu, Terai Hidetomi, Nakamura Hiroaki

    JOURNAL OF NEUROSURGERY-SPINE   25 ( 1 )   39 - 45   2016.07( ISSN:1547-5654

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    DOI: 10.3171/2015.12.SPINE15805

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  • Factors associated with improvement in sagittal spinal alignment after microendoscopic laminotomy in patients with lumbar spinal canal stenosis. Reviewed

    Dohzono S, Toyoda H, Takahashi S, Matsumoto T, Suzuki A, Terai H, Nakamura H

    Journal of neurosurgery. Spine   25 ( 1 )   39 - 45   2016.07( ISSN:1547-5654

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    DOI: 10.3171/2015.12.SPINE15805

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  • Duality picture of Superconductor-insulator transitions on Superconducting nanowire. Reviewed

    Makise K, Terai H, Tominari Y, Tanaka S, Shinozaki B

    Scientific reports   6   27001   2016.06

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    DOI: 10.1038/srep27001

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  • Prognosis of middle column injury at the time of osteoporotic vertebral fracture Reviewed

    59 ( 7 )   903 - 907   2016.06( ISSN:03874095

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    DOI: 10.18888/j00767.2016273416

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  • 腰椎椎弓部分切除術の術後疼痛に対して脊髄後枝内側枝ブロックを含めた術中ロピバカイン局所投与は有効である Reviewed

    林 和憲, 星野 雅俊, 豊田 宏光, 高橋 真治, 寺井 秀富, 鈴木 亨暢, 玉井 孝司, 大山 翔一朗, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   7 ( 6 )   1065 - 1069   2016.06( ISSN:1884-7137

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    腰椎除圧術に対し、脊髄後枝ブロックと皮神経ブロックを含めた、術中ロピバカイン局所注射法(DRCCR)を考案した。DRCCRを施行した20例と年齢性別手術椎間をマッチさせた対照群20例を比較検討。局注群で術後24時間まで有意に創部痛VASが少なく、14日目まで少ない傾向がみられた。局注に伴う重大な合併症は認めなかった。DRCCRは従来の鎮痛法と比較し術後早期の創部痛軽減に有効かつ簡便、安全であった。(著者抄録)

  • 【骨粗鬆症性椎体骨折-治療の現状と問題点】骨粗鬆症性椎体骨折における後壁損傷の追跡調査 Reviewed

    星野 雅俊, 高橋 真治, 辻尾 唯雄, 寺井 秀富, 中村 博亮

    整形・災害外科   59 ( 7 )   903 - 907   2016.06( ISSN:0387-4095

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  • 腰椎椎弓部分切除術の術後疼痛に対して脊髄後枝内側枝ブロックを含めた術中ロピバカイン局所投与は有効である Reviewed

    林 和憲, 星野 雅俊, 豊田 宏光, 高橋 真治, 寺井 秀富, 鈴木 亨暢, 玉井 孝司, 大山 翔一朗, 中村 博亮

    Journal of Spine Research   7 ( 6 )   1065 - 1069   2016.06( ISSN:1884-7137

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    腰椎除圧術に対し、脊髄後枝ブロックと皮神経ブロックを含めた、術中ロピバカイン局所注射法(DRCCR)を考案した。DRCCRを施行した20例と年齢性別手術椎間をマッチさせた対照群20例を比較検討。局注群で術後24時間まで有意に創部痛VASが少なく、14日目まで少ない傾向がみられた。局注に伴う重大な合併症は認めなかった。DRCCRは従来の鎮痛法と比較し術後早期の創部痛軽減に有効かつ簡便、安全であった。(著者抄録)

  • Effect of Spinal Fixation in Rabbits With Metastatic Tumor Using a Novel Spinal Fusion Model. Reviewed

    Yamada K, Terai H, Matsumoto T, Okabe T, Suzuki A, Toyoda H, Nakamura H

    Clinical spine surgery   29 ( 4 )   E215 - 21   2016.05( ISSN:2380-0186

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    DOI: 10.1097/BSD.0b013e3182693f56

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  • 2つの側方経路腰椎椎体間固定(OLIF/XLIF)の手術成績の比較 Reviewed

    山田 祐太郎, 星野 雅俊, 寺井 秀富, 豊田 宏光, 鈴木 亨暢, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   59 ( 3 )   449 - 450   2016.05( ISSN:0008-9443

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    著者らは2椎間以内の側方経路腰椎椎体間固定を行った19例の短期成績について、術式別にOLIF群9例とXLIF群10例に分け、比較検討した。その結果、1)手術時間、総出血量、JOAスコア改善率は両群間で有意差がなく、術前症状は全例で改善が得られた。2)合併症はOLIF群で腹膜損傷を1例に認められた。術後1週時点の大腿部痛はOLIF群が3例、XLIF群が8例と、XLIF群で有意に多く認められたが、全例、術後3週以内に消失していた。3)画像評価として、椎間板高・椎間前彎角の変化量および脊柱管前後径拡大率には有意差を認められなかったが、OLIF群ではケージが前方に設置される傾向にあった。

  • 頸椎手術後に後彎変形が進行し頸椎前方・後方矯正固定術を行った関節リウマチの1例 Reviewed

    上田 昭一, 豊田 宏光, 寺井 秀富, 星野 雅俊, 鈴木 亨暢, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   59 ( 3 )   499 - 500   2016.05( ISSN:0008-9443

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    66歳女性(関節リウマチ罹病歴19年)。脊髄症に対する椎弓形成術後4年目に脊髄麻痺症状が再燃し、入院となった。椎弓X線では頸椎後彎変形の進行がみられ、MRIおよびCTでは後彎、すべりの進行によりC3/4レベルの再圧迫が認められた。入院後はハローベストを装着することで、頸椎アライメントの改善が得られ。それに伴い、筋力もMMT 3から4程度に回復した。以後、臨床経過から頸椎後彎による脊髄症と診断され、頸椎前方・後方矯正固定術を施行した。その結果、術後MMTは上下肢ともに4から5レベルまで回復し、術後矯正損失は認めず、JOAスコアも術前の4点から術後9.5点まで改善した。

  • Effect of Spinal Fixation in Rabbits With Metastatic Tumor Using a Novel Spinal Fusion Model Reviewed

    Yamada Kentaro, Terai Hidetomi, Matsumoto Tomiya, Okabe Takahiro, Suzuki Akinobu, Toyoda Hiromitsu, Nakamura Hiroaki

    CLINICAL SPINE SURGERY   29 ( 4 )   E215 - E221   2016.05( ISSN:1536-0652

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  • 2つの側方経路腰椎椎体間固定(OLIF/XLIF)の手術成績の比較 Reviewed

    山田 祐太郎, 星野 雅俊, 寺井 秀富, 豊田 宏光, 鈴木 亨暢, 中村 博亮

    中部日本整形外科災害外科学会雑誌   59 ( 3 )   449 - 450   2016.05( ISSN:0008-9443

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    著者らは2椎間以内の側方経路腰椎椎体間固定を行った19例の短期成績について、術式別にOLIF群9例とXLIF群10例に分け、比較検討した。その結果、1)手術時間、総出血量、JOAスコア改善率は両群間で有意差がなく、術前症状は全例で改善が得られた。2)合併症はOLIF群で腹膜損傷を1例に認められた。術後1週時点の大腿部痛はOLIF群が3例、XLIF群が8例と、XLIF群で有意に多く認められたが、全例、術後3週以内に消失していた。3)画像評価として、椎間板高・椎間前彎角の変化量および脊柱管前後径拡大率には有意差を認められなかったが、OLIF群ではケージが前方に設置される傾向にあった。

  • Effect of Spinal Fixation in Rabbits With Metastatic Tumor Using a Novel Spinal Fusion Model. Reviewed

    Yamada K, Terai H, Matsumoto T, Okabe T, Suzuki A, Toyoda H, Nakamura H

    Clinical spine surgery   29 ( 4 )   E215 - 21   2016.05( ISSN:2380-0186

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    DOI: 10.1097/BSD.0b013e3182693f56

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  • 【脊椎領域におけるスポーツ医学の最近の話題】スポーツ選手の腰椎椎間板ヘルニアに対する内視鏡下後方手術 Reviewed

    寺井 秀富, 中村 博亮

    関節外科   35 ( 5 )   476 - 481   2016.05( ISSN:0286-5394

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  • 頸椎手術後に後彎変形が進行し頸椎前方・後方矯正固定術を行った関節リウマチの1例 Reviewed

    上田 昭一, 豊田 宏光, 寺井 秀富, 星野 雅俊, 鈴木 亨暢, 中村 博亮

    中部日本整形外科災害外科学会雑誌   59 ( 3 )   499 - 500   2016.05( ISSN:0008-9443

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    66歳女性(関節リウマチ罹病歴19年)。脊髄症に対する椎弓形成術後4年目に脊髄麻痺症状が再燃し、入院となった。椎弓X線では頸椎後彎変形の進行がみられ、MRIおよびCTでは後彎、すべりの進行によりC3/4レベルの再圧迫が認められた。入院後はハローベストを装着することで、頸椎アライメントの改善が得られ。それに伴い、筋力もMMT 3から4程度に回復した。以後、臨床経過から頸椎後彎による脊髄症と診断され、頸椎前方・後方矯正固定術を施行した。その結果、術後MMTは上下肢ともに4から5レベルまで回復し、術後矯正損失は認めず、JOAスコアも術前の4点から術後9.5点まで改善した。

  • 治療選択誌上ディベート(第4回) 椎体骨折の治療選択 Balloon Kyphoplasty(BKP)VSインストゥルメンテーション インストゥルメンテーションの立場から Reviewed

    寺井 秀富

    Loco Cure   2 ( 1 )   65 - 69   2016.02( ISSN:2189-4221

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    インストゥルメンテーションよりもBKPを優先的に考える。術式により矯正角度、脊柱アライメントを任意に調整できる。高侵襲である。術前の入念な全身状態の評価と手術計画を。高齢者が多いため、可能な限り短時間で終わらせることができる術式を選択する。再手術まで考えた手術計画を立て、患者への説明をしておく。(著者抄録)

  • Anatomical Location of the Common Iliac Veins at the Level of the Sacrum: Relationship between Perforation Risk and the Trajectory Angle of the Screw Reviewed

    Akhgar Javid, Terai Hidetomi, Rahmani Mohammad Suhrab, Tamai Koji, Suzuki Akinobu, Toyoda Hiromitsu, Hoshino Masatoshi, Ahmadi Sayed Abdullah, Hayashi Kazunori, Nakamura Hiroaki

    BIOMED RESEARCH INTERNATIONAL   2016   1457219   2016( ISSN:2314-6133

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    DOI: 10.1155/2016/1457219

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  • Comparative study of clinical outcomes of lateral lumbar interbody fusion (OLIF/XLIF) Reviewed

    YAMADA Yutaro

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   59 ( 3 )   449 - 450   2016( ISSN:0008-9443

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    DOI: 10.11359/chubu.2016.449

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  • Anterior and posterior fixation for cervical spondylosis of rheumatoid arthritis: a case report Reviewed

    UEDA Shoichi

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   59 ( 3 )   499 - 500   2016( ISSN:0008-9443

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    DOI: 10.11359/chubu.2016.499

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  • 第448回整形外科集談会京阪神地方会 Best Paper Award Reviewed

    小林 祐人, 鈴木 亨暢, 大山 翔一朗, 寺井 秀富, 星野 雅俊, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   59 ( 5 )   1089 - 1090   2016

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    DOI: 10.11359/chubu.2016.1089

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  • Large schwannoma on cervical spine with pharyngeal irritation; A case report Reviewed

    HAYASHI Kazunori

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   59 ( 6 )   1215 - 1216   2016

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    DOI: 10.11359/chubu.2016.1215

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  • Comparative study of clinical outcomes of lateral lumbar interbody fusion (OLIF/XLIF) Reviewed

    YAMADA Yutaro

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   59 ( 3 )   449 - 450   2016( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2016.449

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  • Anatomical Location of the Common Iliac Veins at the Level of the Sacrum: Relationship between Perforation Risk and the Trajectory Angle of the Screw. Reviewed

    Akhgar J, Terai H, Suhrab Rahmani M, Tamai K, Suzuki A, Toyoda H, Hoshino M, Abdullah Ahmadi S, Hayashi K, Nakamura H

    BioMed research international   2016   1457219   2016( ISSN:2314-6133

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    DOI: 10.1155/2016/1457219

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  • Large schwannoma on cervical spine with pharyngeal irritation; A case report Reviewed

    HAYASHI Kazunori

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   59 ( 6 )   1215 - 1216   2016( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2016.1215

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  • Anterior and posterior fixation for cervical spondylosis of rheumatoid arthritis: a case report Reviewed

    UEDA Shoichi

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   59 ( 3 )   499 - 500   2016( ISSN:00089443 ( eISSN:13490885

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.11359/chubu.2016.499

    CiNii Article

  • 第448回整形外科集談会京阪神地方会 Best Paper Award Reviewed

    小林 祐人, 鈴木 亨暢, 大山 翔一朗, 寺井 秀富, 星野 雅俊, 中村 博亮

    中部日本整形外科災害外科学会雑誌   59 ( 5 )   1089 - 1090   2016( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2016.1089

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  • Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer. Reviewed

    Terai H, Tan L, Beauchamp EM, Hatcher JM, Liu Q, Meyerson M, Gray NS, Hammerman PS

    ACS chemical biology   10 ( 12 )   2687 - 96   2015.12( ISSN:1554-8929

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    DOI: 10.1021/acschembio.5b00655

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  • 思春期特発性側彎症に対する剛性の異なる2種類の太径ロッドを用いた後方矯正固定術の矯正効果 Reviewed

    豊田 宏光, 寺井 秀富, 鈴木 亨暢, 林 和憲, 玉井 孝司, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   6 ( 11 )   1607 - 1613   2015.11( ISSN:1884-7137

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    われわれは純チタン製の6.35mm径ロッドを先に凸側挿入し、変形矯正を行った後に、さらに剛性の強いチタン合金製の6.35mmロッドを挿入する術式を考案し、本術式の矯正効果と頂椎の回旋度についての評価を行った。矯正率は、胸椎カーブが主であるLenke 1、2、3群では74.5%、胸腰椎カーブが主であるLenke 5、6では75.8%であった。また、頂椎の回旋角度の改善も認められ、凸側から変形矯正を行っても回旋変形は悪化しないことが判明した。(著者抄録)

  • 思春期特発性側彎症に対する剛性の異なる2種類の太径ロッドを用いた後方矯正固定術の矯正効果 Reviewed

    豊田 宏光, 寺井 秀富, 鈴木 亨暢, 林 和憲, 玉井 孝司, 中村 博亮

    Journal of Spine Research   6 ( 11 )   1607 - 1613   2015.11( ISSN:1884-7137

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    われわれは純チタン製の6.35mm径ロッドを先に凸側挿入し、変形矯正を行った後に、さらに剛性の強いチタン合金製の6.35mmロッドを挿入する術式を考案し、本術式の矯正効果と頂椎の回旋度についての評価を行った。矯正率は、胸椎カーブが主であるLenke 1、2、3群では74.5%、胸腰椎カーブが主であるLenke 5、6では75.8%であった。また、頂椎の回旋角度の改善も認められ、凸側から変形矯正を行っても回旋変形は悪化しないことが判明した。(著者抄録)

  • 延髄から胸髄まで広範囲信号変化と脊髄腫大を来し、脊髄炎との鑑別を要した頸椎後縦靱帯骨化症の1例 Reviewed

    柴田 雄輝, 林 和憲, 星野 雅俊, 豊田 宏光, 寺井 秀富, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   58 ( 5 )   939 - 940   2015.09( ISSN:0008-9443

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    82歳女。歩行困難と巧緻運動障害を主訴とした。10年前より両上肢の痺れが出現し、半年前より歩行困難と巧緻運動障害が生じた。身体所見でRomberg徴候が強陽性であり、Hoffman反射は右側で陽性、Babinski反射は両側で陽性であった。MRIで延髄からT2高位にかけてT1強調像で低〜等信号、T2強調像で高信号の連続した髄内信号変化と脊髄腫大の所見を認め、CTでC6-7に後縦靱帯骨化がみられた。脊髄炎を疑い、各種ウイルス抗体検査、抗AQP抗体およびACEを含めた血液検査および髄液検査を施行した。しかし、検査結果は陰性であったため、頸椎後縦靱帯骨化症および脊髄浮腫と診断した。C3-6椎弓形成とC2、C7部分椎弓切除術を施行したところ、巧緻運動障害が改善した。また、術後1週のMRIで延髄からT2高位にかけて連続した脊髄内信号変化はC5/6に限局するまでに縮小し、脊髄腫大も改善した。術後3ヵ月に四点杖歩行が可能になるまで回復した。

  • 延髄から胸髄まで広範囲信号変化と脊髄腫大を来し、脊髄炎との鑑別を要した頸椎後縦靱帯骨化症の1例 Reviewed

    柴田 雄輝, 林 和憲, 星野 雅俊, 豊田 宏光, 寺井 秀富, 中村 博亮

    中部日本整形外科災害外科学会雑誌   58 ( 5 )   939 - 940   2015.09( ISSN:0008-9443

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    82歳女。歩行困難と巧緻運動障害を主訴とした。10年前より両上肢の痺れが出現し、半年前より歩行困難と巧緻運動障害が生じた。身体所見でRomberg徴候が強陽性であり、Hoffman反射は右側で陽性、Babinski反射は両側で陽性であった。MRIで延髄からT2高位にかけてT1強調像で低〜等信号、T2強調像で高信号の連続した髄内信号変化と脊髄腫大の所見を認め、CTでC6-7に後縦靱帯骨化がみられた。脊髄炎を疑い、各種ウイルス抗体検査、抗AQP抗体およびACEを含めた血液検査および髄液検査を施行した。しかし、検査結果は陰性であったため、頸椎後縦靱帯骨化症および脊髄浮腫と診断した。C3-6椎弓形成とC2、C7部分椎弓切除術を施行したところ、巧緻運動障害が改善した。また、術後1週のMRIで延髄からT2高位にかけて連続した脊髄内信号変化はC5/6に限局するまでに縮小し、脊髄腫大も改善した。術後3ヵ月に四点杖歩行が可能になるまで回復した。

  • 腰椎すべり症に対する内視鏡下椎弓切除術の治療成績 すべりのない腰部脊柱管狭窄症の治療成績との比較 Reviewed

    鈴木 亨暢, 豊田 宏光, 寺井 秀富, 林 和憲, 玉井 孝司, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   6 ( 8 )   1325 - 1330   2015.08( ISSN:1884-7137

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    内視鏡下椎弓切除術を行い除圧レベルにすべりがあるすべり有群36例とすべり無群46例の2群にて術後成績を比較・検討した。術後JOA score及び各VAS値は両群共に術後有意な改善が認められたが、2群間には有意差を認めなかった。しかし改善率25%以下である成績不良例の症例はすべり有群にのみ3例8%に認められた。腰椎すべり症に対しても内視鏡下椎弓切除術の治療成績はすべりの無い症例と同等で概ね良好だが、成績不良例が少数存在する。(著者抄録)

  • 腰椎すべり症に対する内視鏡下椎弓切除術の治療成績 すべりのない腰部脊柱管狭窄症の治療成績との比較 Reviewed

    鈴木 亨暢, 豊田 宏光, 寺井 秀富, 林 和憲, 玉井 孝司, 中村 博亮

    Journal of Spine Research   6 ( 8 )   1325 - 1330   2015.08( ISSN:1884-7137

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    内視鏡下椎弓切除術を行い除圧レベルにすべりがあるすべり有群36例とすべり無群46例の2群にて術後成績を比較・検討した。術後JOA score及び各VAS値は両群共に術後有意な改善が認められたが、2群間には有意差を認めなかった。しかし改善率25%以下である成績不良例の症例はすべり有群にのみ3例8%に認められた。腰椎すべり症に対しても内視鏡下椎弓切除術の治療成績はすべりの無い症例と同等で概ね良好だが、成績不良例が少数存在する。(著者抄録)

  • The influence of preoperative spinal sagittal balance on clinical outcomes after microendoscopic laminotomy in patients with lumbar spinal canal stenosis Reviewed

    Dohzono Sho, Toyoda Hiromitsu, Matsumoto Tomiya, Suzuki Akinobu, Terai Hidetomi, Nakamura Hiroaki

    JOURNAL OF NEUROSURGERY-SPINE   23 ( 1 )   49 - 54   2015.07( ISSN:1547-5654

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    DOI: 10.3171/2014.11.SPINE14452

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  • The influence of preoperative spinal sagittal balance on clinical outcomes after microendoscopic laminotomy in patients with lumbar spinal canal stenosis. Reviewed

    Dohzono S, Toyoda H, Matsumoto T, Suzuki A, Terai H, Nakamura H

    Journal of neurosurgery. Spine   23 ( 1 )   49 - 54   2015.07( ISSN:1547-5654

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    DOI: 10.3171/2014.11.SPINE14452

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  • PCSK5 mutation in a patient with the VACTERL association. Reviewed

    Nakamura Y, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, Matsubara M, Fujioka F, Inagaki H, Kobayashi T, Kimura T, Kurahashi H, Kato H

    BMC research notes   8   228   2015.06

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    DOI: 10.1186/s13104-015-1166-0

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  • PCSK5 mutation in a patient with the VACTERL association. Reviewed

    Nakamura Y, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, Matsubara M, Fujioka F, Inagaki H, Kobayashi T, Kimura T, Kurahashi H, Kato H

    BMC research notes   8   228   2015.06

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    DOI: 10.1186/s13104-015-1166-0

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  • 【腰椎椎間板ヘルニアに対する手術療法 低侵襲手術の実際と合併症対策】手術の実際 内視鏡を用いた椎間板ヘルニア摘出術 Reviewed

    寺井 秀富, 中村 博亮

    整形外科Surgical Technique   5 ( 3 )   271 - 278   2015.06( ISSN:2185-7733

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  • A Phase II study of S-1 and irinotecan combination therapy in previously treated patients with advanced non-small cell lung cancer. Reviewed

    Ikemura S, Naoki K, Yasuda H, Kawada I, Yoda S, Terai H, Sato T, Ishioka K, Arai D, Ohgino K, Kamata H, Miyata J, Kabata H, Betsuyaku T, Soejima K

    Japanese journal of clinical oncology   45 ( 4 )   356 - 61   2015.04( ISSN:0368-2811

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    DOI: 10.1093/jjco/hyu226

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  • A phase II study of biweekly paclitaxel and carboplatin in elderly patients with advanced non-small cell lung cancer. Reviewed

    Soejima K, Naoki K, Ishioka K, Nakamura M, Nakatani M, Kawada I, Watanabe H, Nakachi I, Yasuda H, Satomi R, Nakayama S, Yoda S, Ikemura S, Terai H, Sato T, Ohgino K, Arai D, Tani T, Kuroda A, Nishino M, Betsuyaku T

    Cancer chemotherapy and pharmacology   75 ( 3 )   513 - 9   2015.03( ISSN:0344-5704

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    DOI: 10.1007/s00280-014-2673-8

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  • 骨粗鬆症性椎体骨折の長期予後(5年以上) 生存・ADL・遺残疼痛に影響する因子解析 Reviewed

    星野 雅俊, 寺井 秀富, 辻尾 唯雄, 鈴木 亨暢, 並川 崇, 加藤 相勲, 松村 昭, 高岡 邦夫, 中村 博亮

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   6 ( 1 )   12 - 16   2015.01( ISSN:1884-7137

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    骨粗鬆症性椎体骨折患者で5年以上追跡できた107例を対象とし、死亡や寝たきりなどの重篤な長期予後に関連する因子を解析した。追跡調査時の生存状況は死亡が26例、ADLは寝たきりが11例、準寝たきりが19例、自立が51例であった。多変量解析の結果、受傷時の椎体後壁損傷と6ヵ月時の高度椎体圧潰が長期予後には最も関連しており、治療上最も留意すべきポイントと考えられた。(著者抄録)

  • 骨粗鬆症性椎体骨折の長期予後(5年以上) 生存・ADL・遺残疼痛に影響する因子解析 Reviewed

    星野 雅俊, 寺井 秀富, 辻尾 唯雄, 鈴木 亨暢, 並川 崇, 加藤 相勲, 松村 昭, 高岡 邦夫, 中村 博亮

    Journal of Spine Research   6 ( 1 )   12 - 16   2015.01( ISSN:1884-7137

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    骨粗鬆症性椎体骨折患者で5年以上追跡できた107例を対象とし、死亡や寝たきりなどの重篤な長期予後に関連する因子を解析した。追跡調査時の生存状況は死亡が26例、ADLは寝たきりが11例、準寝たきりが19例、自立が51例であった。多変量解析の結果、受傷時の椎体後壁損傷と6ヵ月時の高度椎体圧潰が長期予後には最も関連しており、治療上最も留意すべきポイントと考えられた。(著者抄録)

  • A new corrective technique for adolescent idiopathic scoliosis: convex manipulation using 6.35 mm diameter pure titanium rod followed by concave fixation using 6.35 mm diameter titanium alloy Reviewed

    Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Dozono Sho, Yasuda Hiroyuki, Tamai Koji, Nakamura Hiroaki

    SCOLIOSIS AND SPINAL DISORDERS   10 ( Suppl 2 )   S14   2015( ISSN:1748-7161

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    DOI: 10.1186/1748-7161-10-S2-S14

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  • A case of ossification of posterior longitudinal ligament presenting huge intensity change and spinal cord swelling from medulla to thoracic spine needed to distinguish from myelitis Reviewed

    SHIBATA Yuki

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   58 ( 5 )   939 - 940   2015( ISSN:0008-9443

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    DOI: 10.11359/chubu.2015.939

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  • Which is the best schedule of autologous blood storage for preoperative adolescent idiopathic scoliosis patients? Reviewed

    Tamai Koji, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Yasuda Hiroyuki, Dozono Shou, Nakamura Hiroaki

    SCOLIOSIS AND SPINAL DISORDERS   10 ( Suppl 2 )   S11   2015( ISSN:1748-7161

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    DOI: 10.1186/1748-7161-10-S2-S11

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  • A new corrective technique for adolescent idiopathic scoliosis: convex manipulation using 6.35 mm diameter pure titanium rod followed by concave fixation using 6.35 mm diameter titanium alloy. Reviewed

    Terai H, Toyoda H, Suzuki A, Dozono S, Yasuda H, Tamai K, Nakamura H

    Scoliosis   10 ( Suppl 2 )   S14   2015

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    DOI: 10.1186/1748-7161-10-S2-S14

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  • Which is the best schedule of autologous blood storage for preoperative adolescent idiopathic scoliosis patients? Reviewed

    Tamai K, Terai H, Toyoda H, Suzuki A, Yasuda H, Dozono S, Nakamura H

    Scoliosis   10 ( Suppl 2 )   S11   2015

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    DOI: 10.1186/1748-7161-10-S2-S11

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  • A case of ossification of posterior longitudinal ligament presenting huge intensity change and spinal cord swelling from medulla to thoracic spine needed to distinguish from myelitis Reviewed

    SHIBATA Yuki

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   58 ( 5 )   939 - 940   2015( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2015.939

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  • Efficient generation of twin photons at telecom wavelengths with 2.5 GHz repetition-rate-tunable comb laser. Reviewed

    Jin RB, Shimizu R, Morohashi I, Wakui K, Takeoka M, Izumi S, Sakamoto T, Fujiwara M, Yamashita T, Miki S, Terai H, Wang Z, Sasaki M

    Scientific reports   4   7468   2014.12

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    DOI: 10.1038/srep07468

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  • Distal embolic brain infarction due to recanalization of asymptomatic vertebral artery occlusion resulting from cervical spine injury: a case report. Reviewed

    Nakao Y, Terai H

    Journal of chiropractic medicine   13 ( 4 )   266 - 72   2014.12( ISSN:1556-3707

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    DOI: 10.1016/j.jcm.2014.09.002

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  • 【骨粗鬆症性椎体骨折治療のコツとpitfall】骨粗鬆症性椎体骨折に対するリン酸カルシウムセメントを用いた椎体形成術のコツとpitfall 骨セメント塊逸脱や再圧潰発生の危険因子からみた椎体形成術の適応と限界 Reviewed

    豊田 宏光, 寺井 秀富, 中村 博亮

    整形外科最小侵襲手術ジャーナル   ( 73 )   53 - 62   2014.12( ISSN:1342-3991

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    当院では、骨粗鬆症性椎体骨折骨癒合不全に対して経椎弓根的に挿入した内視鏡下に椎体クレフト腔内を掻爬し、ウロマチックバルーンを用いてリン酸カルシウムペーストの充填空間を形成する椎体形成術を行っている。1年以上経過観察が可能であった49椎体の臨床成績は良好であり、除痛効果、ADL改善ともに優れた術式であった。しかし、続発性新規椎体骨折や術後再圧潰(再骨折)、骨セメント塊の逸脱などが課題として挙げられた。多変量解析を用いて、術後再圧潰、骨セメント塊の逸脱の危険因子を検討した結果、American Society of Anesthesiologists-Physical Statusが3以上、椎体壁損傷数が3以上であることが、年齢や骨密度よりも重要な因子であることが判明した。椎体形成術単独療法の良い適応は、椎体壁損傷数が2以下の生体材料を格納する椎体の壁がしっかりと保たれた椎体骨折であり、3以上の高度椎体壁破壊例に対しては、後方インストゥルメンテーションの併用が推奨される。(著者抄録)

  • Fluorescence correlation spectroscopy with visible-wavelength superconducting nanowire single-photon detector. Reviewed

    Yamashita T, Liu D, Miki S, Yamamoto J, Haraguchi T, Kinjo M, Hiraoka Y, Wang Z, Terai H

    Optics express   22 ( 23 )   28783 - 9   2014.11

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    DOI: 10.1364/OE.22.028783

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  • Embolic brain infarction related to posttraumatic occlusion of vertebral artery resulting from cervical spine injury: a case report. Reviewed

    Nakao Y, Terai H

    Journal of medical case reports   8   344   2014.10

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    DOI: 10.1186/1752-1947-8-344

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  • 整形外科の手術手技-私はこうしている 脊椎・骨盤・体幹 腰椎 腰部脊柱管狭窄症に対する棘突起縦割式片側進入両側除圧術 Reviewed

    鈴木 亨暢, 玉井 孝司, 寺井 秀富, 豊田 宏光, 中村 博亮

    別冊整形外科   1 ( 66 )   222 - 226   2014.10( ISSN:02871645

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    DOI: 10.15106/j04037.2015040721

  • 【整形外科の手術手技-私はこうしている】 脊椎・骨盤・体幹 腰椎 腰部脊柱管狭窄症に対する棘突起縦割式片側進入両側除圧術 Reviewed

    鈴木 亨暢, 玉井 孝司, 寺井 秀富, 豊田 宏光, 中村 博亮

    (株)南江堂 別冊整形外科   ( 66 )   222 - 226   2014.10( ISSN:0287-1645

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    腰部脊柱管狭窄症に対する棘突起縦割式片側進入両側除圧術について検討した。腰部脊柱管狭窄症に対して棘突起縦割式片側進人両側除圧を行い、2年以上経過観察可能であった34例(縦割群)を対象とした。通常の傍脊柱筋を棘突起から切離する方法で片側進入両側除圧術を行った34例(筋切離群)を対照群とした。術前腰痛VASは縦割群で有意に高かった。1椎間あたりの平均手術時間は、有意に縦割群のほうが短かったが、1椎間あたり平均出血量は両群間に有意差は認めなかった。両群ともに術前JOAスコアおよび各種VASは術後有意に改善し、術後2年時まで改善は保たれた。術後2年時の下肢しびれVASは有意に縦割群で低かったが、その他の項目は両群間に有意差は認めなかった。再手術例の割合に両群間で有意差は認めなかった。縦割群における術後2年時点での縦割棘突起の癒合率は86.7%であった。

  • Efficacy of coronary artery screening tests and intervention in hemodialysis patients. Reviewed

    Daimon S, Mizushima I, Hamano R, Terai H

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy   18 ( 5 )   443 - 9   2014.10( ISSN:1744-9979

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    DOI: 10.1111/1744-9987.12167

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  • 【整形外科の手術手技-私はこうしている】脊椎・骨盤・体幹 腰椎 腰部脊柱管狭窄症に対する棘突起縦割式片側進入両側除圧術 Reviewed

    鈴木 亨暢, 玉井 孝司, 寺井 秀富, 豊田 宏光, 中村 博亮

    別冊整形外科   ( 66 )   222 - 226   2014.10( ISSN:0287-1645

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    腰部脊柱管狭窄症に対する棘突起縦割式片側進入両側除圧術について検討した。腰部脊柱管狭窄症に対して棘突起縦割式片側進人両側除圧を行い、2年以上経過観察可能であった34例(縦割群)を対象とした。通常の傍脊柱筋を棘突起から切離する方法で片側進入両側除圧術を行った34例(筋切離群)を対照群とした。術前腰痛VASは縦割群で有意に高かった。1椎間あたりの平均手術時間は、有意に縦割群のほうが短かったが、1椎間あたり平均出血量は両群間に有意差は認めなかった。両群ともに術前JOAスコアおよび各種VASは術後有意に改善し、術後2年時まで改善は保たれた。術後2年時の下肢しびれVASは有意に縦割群で低かったが、その他の項目は両群間に有意差は認めなかった。再手術例の割合に両群間で有意差は認めなかった。縦割群における術後2年時点での縦割棘突起の癒合率は86.7%であった。

  • Claudin-1 is a novel target of miR-375 in non-small-cell lung cancer. Reviewed

    Yoda S, Soejima K, Hamamoto J, Yasuda H, Nakayama S, Satomi R, Terai H, Ikemura S, Sato T, Naoki K, Betsuyaku T

    Lung cancer (Amsterdam, Netherlands)   85 ( 3 )   366 - 72   2014.09( ISSN:0169-5002

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    DOI: 10.1016/j.lungcan.2014.06.009

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  • Spinopelvic alignment of diffuse idiopathic skeletal hyperostosis in lumbar spinal stenosis Reviewed

    Yamada Kentaro, Toyoda Hiromitsu, Terai Hidetomi, Takahashi Shinji, Nakamura Hiroaki

    EUROPEAN SPINE JOURNAL   23 ( 6 )   1302 - 1308   2014.06( ISSN:0940-6719

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    DOI: 10.1007/s00586-013-3154-1

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  • THE FEATURES OF DEGENERATIVE LUMBAR SCOLIOSIS IN RHEUMATOID ARTHRITIS PATIENTS - MATCHED COHORT STUDY Reviewed

    Anno S., Yasuda H., Suzuki A., Koike T., Inui K., Terai H., Toyoda H., Tada M., Sugioka Y., Okano T., Yamada K., Takahashi S., Mamoto K., Nakamura H.

    ANNALS OF THE RHEUMATIC DISEASES   73   305 - 305   2014.06( ISSN:0003-4967

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    DOI: 10.1136/annrheumdis-2014-eular.2459

  • Spinopelvic alignment of diffuse idiopathic skeletal hyperostosis in lumbar spinal stenosis. Reviewed

    Yamada K, Toyoda H, Terai H, Takahashi S, Nakamura H

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   23 ( 6 )   1302 - 8   2014.06( ISSN:0940-6719

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    DOI: 10.1007/s00586-013-3154-1

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  • Tandem keyhole foraminotomy in the treatment of cervical radiculopathy: retrospective review of 35 cases Reviewed

    Terai Hidetomi, Suzuki Akinobu, Toyoda Hiromitsu, Yasuda Hiroyuki, Kaneda Kunikazu, Katsutani Hirofumi, Nakamura Hiroaki

    JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH   9   38   2014.05( ISSN:1749-799X

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    DOI: 10.1186/1749-799X-9-38

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  • Tandem keyhole foraminotomy in the treatment of cervical radiculopathy: retrospective review of 35 cases. Reviewed

    Terai H, Suzuki A, Toyoda H, Yasuda H, Kaneda K, Katsutani H, Nakamura H

    Journal of orthopaedic surgery and research   9   38   2014.05

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    DOI: 10.1186/1749-799X-9-38

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  • A 64-pixel NbTiN superconducting nanowire single-photon detector array for spatially resolved photon detection. Reviewed

    Miki S, Yamashita T, Wang Z, Terai H

    Optics express   22 ( 7 )   7811 - 20   2014.04

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    DOI: 10.1364/OE.22.007811

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  • Expression of fibroblast growth factor 9 is associated with poor prognosis in patients with resected non-small cell lung cancer. Reviewed

    Ohgino K, Soejima K, Yasuda H, Hayashi Y, Hamamoto J, Naoki K, Arai D, Ishioka K, Sato T, Terai H, Ikemura S, Yoda S, Tani T, Kuroda A, Betsuyaku T

    Lung cancer (Amsterdam, Netherlands)   83 ( 1 )   90 - 6   2014.01( ISSN:0169-5002

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    DOI: 10.1016/j.lungcan.2013.10.016

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  • Radiographic Evaluation of Segmental Motion of Scoliotic Wedging Segment in Degenerative Lumbar Scoliosis Reviewed

    Yasuda Hiyoyuki, Matsumura Akira, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Dozono Sho, Nakamura Hiroaki

    JOURNAL OF SPINAL DISORDERS & TECHNIQUES   26 ( 7 )   379 - 384   2013.10( ISSN:1536-0652

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    DOI: 10.1097/BSD.0b013e31824a4129

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  • [Development and evaluation of the Japanese remote associates test]. Reviewed

    Terai H, Miwa K, Asami K

    Shinrigaku kenkyu : The Japanese journal of psychology   84 ( 4 )   419 - 28   2013.10( ISSN:0021-5236

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    DOI: 10.4992/jjpsy.84.419

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  • Radiographic evaluation of segmental motion of scoliotic wedging segment in degenerative lumbar scoliosis. Reviewed

    Yasuda H, Matsumura A, Terai H, Toyoda H, Suzuki A, Dozono S, Nakamura H

    Journal of spinal disorders & techniques   26 ( 7 )   379 - 84   2013.10( ISSN:1536-0652

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    DOI: 10.1097/BSD.0b013e31824a4129

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  • A case report of intradural lumbar disc herniation Reviewed

    MATSUMOTO Tomiya

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   56 ( 4 )   863 - 864   2013.07( ISSN:00089443

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    DOI: 10.11359/chubu.2013.863

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  • 切迫骨折に先立つ長骨転移に対する内部固定の役割 実験モデル(The role of internal fixation for long bone metastasis prior to impending fracture: an experimental model) Reviewed

    Ibrahim Mohammad, Terai Hidetomi, Yamada Kentaro, Suzuki Akinobu, Toyoda Hiromitsu, Nakamura Hiroaki

    (公社)日本整形外科学会 Journal of Orthopaedic Science   18 ( 4 )   659 - 666   2013.07( ISSN:0949-2658

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    内部固定による長骨転移モデルを確立し、切迫骨折に先立つ長骨転移に対する予防的内部固定の骨破壊、腫瘍進行、死亡に及ぼす影響について検討した。ウサギ45匹を均等に内部固定、対照、シャムの3群に分け、脛骨にVX2腫瘍細胞を移植した。ウサギをX線とCTでモニターし、2週間ごとに血清検査を行った。固定群に比べてシャム群と対照群でウサギ脛骨の有意に高い骨破壊率が認められた。3週間目に固定群、シャム群、対照群でそれぞれ0.2、0.4、2.3%の容積骨量減少を認め、5週目にはそれぞれ1.2、2.5、6.1%に増加した。固定群はシャム群と対照群に比べ、有意な生存延長を示した。予防的内部固定は骨破壊と腫瘍進行を抑制し、長骨転移患者の生存期間を延長することが示唆された。

  • 硬膜内に脱出した腰椎椎板ヘルニアの1例 Reviewed

    松本 富哉, 豊田 宏光, 寺井 秀富, 堂園 将, 堀 悠介, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   56 ( 4 )   863 - 864   2013.07( ISSN:0008-9443

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    63歳男。3年ほど前から腰痛、右臀部から下腿外側痛が出現した。腰椎椎間板ヘルニアを指摘され、保存治療にて軽快していた。突然激しい右臀部から下腿外側痛が出現した。MRIの矢状断像でL4/5椎間板の後方への突出、また硬膜内にT1、T2ともに等信号の腫瘤陰影をみとめ、水平断像では椎間板レベルでは硬膜嚢の連続性の途絶、また椎弓根レベルでは硬膜内に腫瘤陰影をみとめた。CTでL4/5椎間板内、脊柱管内にガス像をみとめた。L4/5椎間板造影、椎間板造影後CTでは硬膜管内への造影剤の流入をみとめた。硬膜内腰椎椎間板ヘルニアと診断し、手術を施行した。足部のしびれが軽度残存しているが、筋力低下、疼痛は消失した。

  • The role of internal fixation for long bone metastasis prior to impending fracture: an experimental model Reviewed

    Ibrahim Mohammad, Terai Hidetomi, Yamada Kentaro, Suzuki Akinobu, Toyoda Hiromitsu, Nakamura Hiroaki

    JOURNAL OF ORTHOPAEDIC SCIENCE   18 ( 4 )   659 - 666   2013.07( ISSN:0949-2658

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    DOI: 10.1007/s00776-013-0380-7

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  • Activation of the FGF2-FGFR1 autocrine pathway: a novel mechanism of acquired resistance to gefitinib in NSCLC. Reviewed

    Terai H, Soejima K, Yasuda H, Nakayama S, Hamamoto J, Arai D, Ishioka K, Ohgino K, Ikemura S, Sato T, Yoda S, Satomi R, Naoki K, Betsuyaku T

    Molecular cancer research : MCR   11 ( 7 )   759 - 67   2013.07( ISSN:1541-7786

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    DOI: 10.1158/1541-7786.MCR-12-0652

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  • The role of internal fixation for long bone metastasis prior to impending fracture: an experimental model. Reviewed

    Ibrahim M, Terai H, Yamada K, Suzuki A, Toyoda H, Nakamura H

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   18 ( 4 )   659 - 66   2013.07( ISSN:0949-2658

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    DOI: 10.1007/s00776-013-0380-7

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  • 硬膜内に脱出した腰椎椎板ヘルニアの1例 Reviewed

    松本 富哉, 豊田 宏光, 寺井 秀富, 堂園 将, 堀 悠介, 中村 博亮

    中部日本整形外科災害外科学会雑誌   56 ( 4 )   863 - 864   2013.07( ISSN:0008-9443

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    63歳男。3年ほど前から腰痛、右臀部から下腿外側痛が出現した。腰椎椎間板ヘルニアを指摘され、保存治療にて軽快していた。突然激しい右臀部から下腿外側痛が出現した。MRIの矢状断像でL4/5椎間板の後方への突出、また硬膜内にT1、T2ともに等信号の腫瘤陰影をみとめ、水平断像では椎間板レベルでは硬膜嚢の連続性の途絶、また椎弓根レベルでは硬膜内に腫瘤陰影をみとめた。CTでL4/5椎間板内、脊柱管内にガス像をみとめた。L4/5椎間板造影、椎間板造影後CTでは硬膜管内への造影剤の流入をみとめた。硬膜内腰椎椎間板ヘルニアと診断し、手術を施行した。足部のしびれが軽度残存しているが、筋力低下、疼痛は消失した。

  • 切迫骨折に先立つ長骨転移に対する内部固定の役割 実験モデル(The role of internal fixation for long bone metastasis prior to impending fracture: an experimental model) Reviewed

    Ibrahim Mohammad, Terai Hidetomi, Yamada Kentaro, Suzuki Akinobu, Toyoda Hiromitsu, Nakamura Hiroaki

    Journal of Orthopaedic Science   18 ( 4 )   659 - 666   2013.07( ISSN:0949-2658

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    Publishing type:Research paper (scientific journal)  

    内部固定による長骨転移モデルを確立し、切迫骨折に先立つ長骨転移に対する予防的内部固定の骨破壊、腫瘍進行、死亡に及ぼす影響について検討した。ウサギ45匹を均等に内部固定、対照、シャムの3群に分け、脛骨にVX2腫瘍細胞を移植した。ウサギをX線とCTでモニターし、2週間ごとに血清検査を行った。固定群に比べてシャム群と対照群でウサギ脛骨の有意に高い骨破壊率が認められた。3週間目に固定群、シャム群、対照群でそれぞれ0.2、0.4、2.3%の容積骨量減少を認め、5週目にはそれぞれ1.2、2.5、6.1%に増加した。固定群はシャム群と対照群に比べ、有意な生存延長を示した。予防的内部固定は骨破壊と腫瘍進行を抑制し、長骨転移患者の生存期間を延長することが示唆された。

  • Impact of Initial Conservative Treatment Interventions on the Outcomes of Patients With Osteoporotic Vertebral Fractures Reviewed

    Hoshino Masatoshi, Tsujio Tadao, Terai Hidetomi, Namikawa Takashi, Kato Minori, Matsumura Akira, Suzuki Akinobu, Takayama Kazushi, Takaoka Kunio, Nakamura Hiroaki

    SPINE   38 ( 11 )   E641 - E648   2013.05( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e31828ced9d

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  • Impact of initial conservative treatment interventions on the outcomes of patients with osteoporotic vertebral fractures. Reviewed

    Hoshino M, Tsujio T, Terai H, Namikawa T, Kato M, Matsumura A, Suzuki A, Takayama K, Takaoka K, Nakamura H

    Spine   38 ( 11 )   E641 - 8   2013.05( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e31828ced9d

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  • Radiographic evaluation of postoperative bone regrowth after microscopic bilateral decompression via a unilateral approach for degenerative lumbar spondylolisthesis Reviewed

    Dohzono Sho, Matsumura Akira, Terai Hidetomi, Toyoda Hiromitsu, Suzuki Akinobu, Nakamura Hiroaki

    JOURNAL OF NEUROSURGERY-SPINE   18 ( 5 )   472 - 478   2013.05( ISSN:1547-5654

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    DOI: 10.3171/2013.2.SPINE12633

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  • Radiographic evaluation of postoperative bone regrowth after microscopic bilateral decompression via a unilateral approach for degenerative lumbar spondylolisthesis. Reviewed

    Dohzono S, Matsumura A, Terai H, Toyoda H, Suzuki A, Nakamura H

    Journal of neurosurgery. Spine   18 ( 5 )   472 - 8   2013.05( ISSN:1547-5654

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    DOI: 10.3171/2013.2.SPINE12633

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  • 【再生医療の現況と最前線】再生医療の現状と展望 細胞を用いない再生医療 BMPを用いた骨再生治療研究の現状と展望 Reviewed

    寺井 秀富, 中村 博亮, 高岡 邦夫

    整形・災害外科   56 ( 5 )   643 - 649   2013.04( ISSN:0387-4095

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  • Characteristics of Diabetes Associated With Poor Improvements in Clinical Outcomes After Lumbar Spine Surgery Reviewed

    Takahashi Shinji, Suzuki Akinobu, Toyoda Hiromitsu, Terai Hidetomi, Dohzono Sho, Yamada Kentarou, Matsumoto Tomiya, Yasuda Hiroyuki, Tsukiyama Kuniaki, Shinohara Yoshikazu, Ibrahim Mohammad, Nakamura Hiroaki

    SPINE   38 ( 6 )   516 - 522   2013.03( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e318273583a

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  • Characteristics of Diabetes Associated With Poor Improvements in Clinical Outcomes After Lumbar Spine Surgery Reviewed

    TAKAHASHI Shinji, SUZUKI Akinobu, TOYODA Hiromitsu, TERAI Hidetomi, DOHZONO Sho, YAMADA Kentarou, MATSUMOTO Tomiya, YASUDA Hiroyuki, TSUKIYAMA Kuniaki, SHINOHARA Yoshikazu, IBRAHIM Mohammad, NAKAMURA Hiroaki

    Spine   38 ( 6 )   516 - 522   2013.03( ISSN:03622436

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  • Characteristics of Diabetes Associated With Poor Improvements in Clinical Outcomes After Lumbar Spine Surgery Reviewed

    TAKAHASHI Shinji, SUZUKI Akinobu, TOYODA Hiromitsu, TERAI Hidetomi, DOHZONO Sho, YAMADA Kentarou, MATSUMOTO Tomiya, YASUDA Hiroyuki, TSUKIYAMA Kuniaki, SHINOHARA Yoshikazu, IBRAHIM Mohammad, NAKAMURA Hiroaki

    38 ( 6 )   516 - 522   2013.03( ISSN:03622436

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  • Characteristics of diabetes associated with poor improvements in clinical outcomes after lumbar spine surgery. Reviewed

    Takahashi S, Suzuki A, Toyoda H, Terai H, Dohzono S, Yamada K, Matsumoto T, Yasuda H, Tsukiyama K, Shinohara Y, Ibrahim M, Nakamura H

    Spine   38 ( 6 )   516 - 22   2013.03( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e318273583a

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  • 【脊椎椎体骨折の治療】骨粗鬆症性椎体骨折後偽関節に対する内視鏡併用椎体形成術 Reviewed

    寺井 秀富, 豊田 宏光, 中村 博亮

    Orthopaedics   26 ( 3 )   7 - 13   2013.03( ISSN:0914-8124

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    高齢者の増加に伴って骨粗鬆症性椎体骨折後偽関節となる症例が増加している。偽関節レベルでの不安定性が疼痛の原因となっていれば、偽関節腔にセメントを注入する椎体形成術によって疼痛や歩行機能障害の劇的な改善が期待できる。椎体形成術にはHAやPMMA、CPC(リン酸カルシウムセメント)が用いられるが、我々は偽関節に対してはCPCを用いている。椎体内で長期にCPCを安定させるには、ある程度大きなセメント塊を形成させる必要がある。そのためにはセメント注入スペース確保のための偽関節腔掻爬が重要なステップとなる。本稿ではバルーンを使って偽関節腔を広げた後に内視鏡を用いて偽関節腔内を掻爬し、十分なセメント注入スペースを確保する術式を詳説し、当院で施行した本法の手術加療成績を併せて報告する。(著者抄録)

  • Countermeasure against tailored bright illumination attack for DPS-QKD. Reviewed

    Honjo T, Fujiwara M, Shimizu K, Tamaki K, Miki S, Yamashita T, Terai H, Wang Z, Sasaki M

    Optics express   21 ( 3 )   2667 - 73   2013.02

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    DOI: 10.1364/OE.21.002667

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  • Treatment of retro-odontoid pseudotumor associated with non-rheumatoid atlantaxial instability : 3 cases Reviewed

    OZAKI Tomonori

    56 ( 1 )   119 - 120   2013.01( ISSN:00089443

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    CiNii Article

  • Transsacral interbody fusion for high-grade spondylolisthesis with cylindrical cage Reviewed

    TERAKAWA Masaki

    56 ( 1 )   103 - 104   2013.01( ISSN:00089443

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    CiNii Article

  • Treatment of retro-odontoid pseudotumor associated with non-rheumatoid atlantaxial instability : 3 cases Reviewed

    OZAKI Tomonori

    56 ( 1 )   119 - 120   2013.01( ISSN:00089443

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    CiNii Article

  • Transsacral interbody fusion for high-grade spondylolisthesis with cylindrical cage Reviewed

    TERAKAWA Masaki

    56 ( 1 )   103 - 104   2013.01( ISSN:00089443

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    CiNii Article

  • 高度(第5)腰椎分離すべり症に対して経仙骨的椎間固定を行った1例 Reviewed

    寺川 雅基, 堂園 将, 豊田 宏光, 寺井 秀富, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   56 ( 1 )   103 - 104   2013.01( ISSN:0008-9443

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  • 軸椎歯突起後方偽腫瘍に対し手術加療を行った超高齢者の2例 Reviewed

    尾崎 友則, 堂園 将, 寺井 秀富, 豊田 宏光, 松本 富哉, 中村 博亮

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会雑誌   56 ( 1 )   119 - 120   2013.01( ISSN:0008-9443

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  • 軸椎歯突起後方偽腫瘍に対し手術加療を行った超高齢者の2例 Reviewed

    尾崎 友則, 堂園 将, 寺井 秀富, 豊田 宏光, 松本 富哉, 中村 博亮

    中部日本整形外科災害外科学会雑誌   56 ( 1 )   119 - 120   2013.01( ISSN:0008-9443

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  • 高度(第5)腰椎分離すべり症に対して経仙骨的椎間固定を行った1例 Reviewed

    寺川 雅基, 堂園 将, 豊田 宏光, 寺井 秀富, 中村 博亮

    中部日本整形外科災害外科学会雑誌   56 ( 1 )   103 - 104   2013.01( ISSN:0008-9443

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  • Treatment of retro-odontoid pseudotumor associated with non-rheumatoid atlantaxial instability: 3 cases Reviewed

    OZAKI Tomonori

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   56 ( 1 )   119 - 120   2013( ISSN:0008-9443

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    DOI: 10.11359/chubu.2013.119

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  • Transsacral interbody fusion for high-grade spondylolisthesis with cylindrical cage Reviewed

    TERAKAWA Masaki

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   56 ( 1 )   103 - 104   2013( ISSN:0008-9443

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    DOI: 10.11359/chubu.2013.103

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  • A case report of intradural lumbar disc herniation Reviewed

    MATSUMOTO Tomiya

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   56 ( 4 )   863 - 864   2013( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2013.863

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  • Transsacral interbody fusion for high-grade spondylolisthesis with cylindrical cage Reviewed

    TERAKAWA Masaki

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   56 ( 1 )   103 - 104   2013( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2013.103

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  • Treatment of retro-odontoid pseudotumor associated with non-rheumatoid atlantaxial instability: 3 cases Reviewed

    OZAKI Tomonori

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   56 ( 1 )   119 - 120   2013( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2013.119

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  • 【1からわかる脊椎圧迫骨折のすべて】手術療法 脊椎圧迫骨折の手術療法 Reviewed

    寺井 秀富

    整形外科看護   17 ( 10 )   986 - 992   2012.10( ISSN:1342-4718

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  • 神経障害を合併した骨粗鬆症性椎体骨折後偽関節に対する内視鏡下椎体形成術の治療成績 Reviewed

    鈴木 亨暢, 寺井 秀富, 豊田 宏光, 中村 博亮, 辻尾 唯雄, 星野 雅俊

    (一社)日本骨折治療学会 骨折   34 ( 3 )   528 - 531   2012.09( ISSN:0287-2285

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    今回我々は神経障害を合併した骨粗鬆症性椎体骨折後偽関節に対して行った内視鏡下椎体形成術単独の治療成績を検討した。対象は13例(男性2例、女性11例)であり、治療成績は腰背部痛VAS、歩行状態、modified Frankel scaleにより評価した。画像的評価として椎体楔状角、椎体高比率および骨片の脊柱管占拠率を測定・評価した。腰背部痛VASは術後有意に改善し、全例で術後歩行可能となった。神経障害は11例で改善が認められた。椎体楔状角および椎体高比率はいずれも術後改善を認めたが、骨片の脊柱管占拠率は術前後で有意な変化は認められなかった。本研究より神経障害を有する骨粗鬆症性椎体骨折後偽関節に対しても椎体形成術のみで一定の治療成績が得られることが判明した。骨片の脊柱管占拠率が変化しないにも関わらず神経障害の改善が認められたことから、椎体の安定化が神経障害の改善に非常に重要であることが示唆された。(著者抄録)

  • 神経障害を合併した骨粗鬆症性椎体骨折後偽関節に対する内視鏡下椎体形成術の治療成績 Reviewed

    鈴木 亨暢, 寺井 秀富, 豊田 宏光, 中村 博亮, 辻尾 唯雄, 星野 雅俊

    骨折   34 ( 3 )   528 - 531   2012.09( ISSN:0287-2285

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    今回我々は神経障害を合併した骨粗鬆症性椎体骨折後偽関節に対して行った内視鏡下椎体形成術単独の治療成績を検討した。対象は13例(男性2例、女性11例)であり、治療成績は腰背部痛VAS、歩行状態、modified Frankel scaleにより評価した。画像的評価として椎体楔状角、椎体高比率および骨片の脊柱管占拠率を測定・評価した。腰背部痛VASは術後有意に改善し、全例で術後歩行可能となった。神経障害は11例で改善が認められた。椎体楔状角および椎体高比率はいずれも術後改善を認めたが、骨片の脊柱管占拠率は術前後で有意な変化は認められなかった。本研究より神経障害を有する骨粗鬆症性椎体骨折後偽関節に対しても椎体形成術のみで一定の治療成績が得られることが判明した。骨片の脊柱管占拠率が変化しないにも関わらず神経障害の改善が認められたことから、椎体の安定化が神経障害の改善に非常に重要であることが示唆された。(著者抄録)

  • Asymmetric Degeneration of Paravertebral Muscles in Patients With Degenerative Lumbar Scoliosis Reviewed

    Shafaq Najibullah, Suzuki Akinobu, Matsumura Akira, Terai Hidetomi, Toyoda Hiromitsu, Yasuda Hiroyuki, Ibrahim Mohammad, Nakamura Hiroaki

    SPINE   37 ( 16 )   1398 - 1406   2012.07( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e31824c767e

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  • Asymmetric degeneration of paravertebral muscles in patients with degenerative lumbar scoliosis. Reviewed

    Shafaq N, Suzuki A, Matsumura A, Terai H, Toyoda H, Yasuda H, Ibrahim M, Nakamura H

    Spine   37 ( 16 )   1398 - 406   2012.07( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e31824c767e

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  • Crosstalk-free operation of multielement superconducting nanowire single-photon detector array integrated with single-flux-quantum circuit in a 0.1 W Gifford-McMahon cryocooler. Reviewed

    Yamashita T, Miki S, Terai H, Makise K, Wang Z

    Optics letters   37 ( 14 )   2982 - 4   2012.07( ISSN:0146-9592

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    DOI: 10.1364/OL.37.002982

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  • 【脊柱再建と生体材料-中・長期成績】生体活性リン酸カルシウムセメントによる椎体形成の中・長期成績 Reviewed

    豊田 宏光, 寺井 秀富, 鈴木 亨暢, 辻尾 唯雄, 星野 雅俊, 中村 博亮

    脊椎脊髄ジャーナル   25 ( 7 )   679 - 686   2012.07( ISSN:0914-4412

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  • スポーツ復帰のための腰椎手術療法 スポーツ選手の腰椎椎間板ヘルニアに対する内視鏡下後方手術の実際 Reviewed

    中村 博亮, 金田 国一, 吉田 玄, 寺井 秀富, 島田 永和

    日本整形外科スポーツ医学会雑誌   32 ( 3 )   215 - 218   2012.07( ISSN:1340-8577

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    われわれはスポーツ選手の腰椎椎間板ヘルニア手術適応症例にMicro Endoscopic Discectomy(以下MED)を施行してきた。対象症例は21例で、年齢は18.2歳、罹患椎間はL3/4間1例、L4/5間12例、L5/S間8例であった。スポーツレベルはすべて学生スポーツのレベルで、サッカー、バレーボールが最も多かった。JOAスコアーは術前平均13.4点が術後27.4点に改善し、その改善率は平均89.8%であった。また21例中、18例が元のスポーツレベルへ復帰し、その復帰率は86%、復帰までの期間は平均3.0ヵ月であった。スポーツ選手に対するMED後の予後は良好で、スポーツ復帰に支障をきたすものではないことが判明した。(著者抄録)

  • Prognostic Factors for Reduction of Activities of Daily Living Following Osteoporotic Vertebral Fractures Reviewed

    Matsumoto Tomiya, Hoshino Masatoshi, Tsujio Tadao, Terai Hidetomi, Namikawa Takashi, Matsumura Akira, Kato Minori, Toyoda Hiromitsu, Suzuki Akinobu, Takayama Kazushi, Takaoka Kunio, Nakamura Hiroaki

    SPINE   37 ( 13 )   1115 - 1121   2012.06( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e3182432823

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  • Prognostic Factors for Reduction of Activities of Daily Living Following Osteoporotic Vertebral Fractures Reviewed

    MATSUMOTO Tomiya, HOSHINO Masatoshi, TSUJIO Tadao, TERAI Hidetomi, NAMIKAWA Takashi, MATSUMURA Akira, KATO Minori, TOYODA Hiromitsu, SUZUKI Akinobu, TAKAYAMA Kazushi, TAKAOKA Kunio, NAKAMURA Hiroaki

    Spine   37 ( 13 )   1115 - 1121   2012.06( ISSN:03622436

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  • Prognostic Factors for Reduction of Activities of Daily Living Following Osteoporotic Vertebral Fractures Reviewed

    MATSUMOTO Tomiya, HOSHINO Masatoshi, TSUJIO Tadao, TERAI Hidetomi, NAMIKAWA Takashi, MATSUMURA Akira, KATO Minori, TOYODA Hiromitsu, SUZUKI Akinobu, TAKAYAMA Kazushi, TAKAOKA Kunio, NAKAMURA Hiroaki

    37 ( 13 )   1115 - 1121   2012.06( ISSN:03622436

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  • Prognostic factors for reduction of activities of daily living following osteoporotic vertebral fractures. Reviewed

    Matsumoto T, Hoshino M, Tsujio T, Terai H, Namikawa T, Matsumura A, Kato M, Toyoda H, Suzuki A, Takayama K, Takaoka K, Nakamura H

    Spine   37 ( 13 )   1115 - 21   2012.06( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e3182432823

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  • Cellularity and Cartilage Matrix Increased in Hypertrophied Ligamentum Flavum Histopathological Analysis Focusing on the Mechanical Stress and Bone Morphogenetic Protein Signaling Reviewed

    Shafaq Najibullah, Suzuki Akinobu, Terai Hidetomi, Wakitani Shigeyuki, Nakamura Hiroaki

    JOURNAL OF SPINAL DISORDERS & TECHNIQUES   25 ( 2 )   107 - 115   2012.04( ISSN:1536-0652

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  • Cellularity and cartilage matrix increased in hypertrophied ligamentum flavum: histopathological analysis focusing on the mechanical stress and bone morphogenetic protein signaling. Reviewed

    Shafaq N, Suzuki A, Terai H, Wakitani S, Nakamura H

    Journal of spinal disorders & techniques   25 ( 2 )   107 - 15   2012.04( ISSN:1536-0652

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    DOI: 10.1097/BSD.0b013e31820bb76e

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  • Cellularity and cartilage matrix increased in hypertrophied ligamentum flavum: histopathological analysis focusing on the mechanical stress and bone morphogenetic protein signaling. Reviewed

    Shafaq N, Suzuki A, Terai H, Wakitani S, Nakamura H

    Journal of spinal disorders & techniques   25 ( 2 )   107 - 15   2012.04( ISSN:1536-0652

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    DOI: 10.1097/BSD.0b013e31820bb76e

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  • [A case of elderly advanced squamous cell lung carcinoma successfully treated with nedaplatin and S-1 combination chemotherapy]. Reviewed

    Terai H, Soejima K, Naoki K, Ikemura S, Ogura-Tomomatsu H, Sato T, Asano K, Betsuyaku T

    Gan to kagaku ryoho. Cancer & chemotherapy   39 ( 3 )   429 - 32   2012.03( ISSN:0385-0684

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  • 骨粗鬆症性椎体骨折後QOL低下に関与する因子についての調査研究 Reviewed

    豊田 宏光, 松本 富哉, 星野 雅俊, 辻尾 唯雄, 寺井 秀富, 並川 崇, 松村 昭, 加藤 相勲, 鈴木 亨暢, 高山 和士, 高岡 邦夫, 中村 博亮

    ライフサイエンス出版(株) Osteoporosis Japan   20 ( 1 )   70 - 73   2012.02( ISSN:0919-6307

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    骨粗鬆症性椎体骨折患者310例(男性44例、女性266例、年齢64〜93歳、平均年齢75.8歳)を対象に受傷時と受傷後6ヵ月目のQOL/ADL評価を行い、QOL低下に関与する因子について検討した。その結果、QOL回復を阻害する因子として「椎体後壁に損傷を認める」と「定期的な運動をしていない」が有意な危険因子として抽出された。特に椎体後壁に損傷を認める症例では認めない症例と比較し、受傷後6ヵ月目のVAS、椎体高比率、骨折部の骨癒合が得られていない偽関節になる割合が有意に高いことが判明した。

  • 骨粗鬆症性椎体骨折後QOL低下に関与する因子についての調査研究 Reviewed

    豊田 宏光, 松本 富哉, 星野 雅俊, 辻尾 唯雄, 寺井 秀富, 並川 崇, 松村 昭, 加藤 相勲, 鈴木 亨暢, 高山 和士, 高岡 邦夫, 中村 博亮

    Osteoporosis Japan   20 ( 1 )   70 - 73   2012.02( ISSN:0919-6307

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    骨粗鬆症性椎体骨折患者310例(男性44例、女性266例、年齢64〜93歳、平均年齢75.8歳)を対象に受傷時と受傷後6ヵ月目のQOL/ADL評価を行い、QOL低下に関与する因子について検討した。その結果、QOL回復を阻害する因子として「椎体後壁に損傷を認める」と「定期的な運動をしていない」が有意な危険因子として抽出された。特に椎体後壁に損傷を認める症例では認めない症例と比較し、受傷後6ヵ月目のVAS、椎体高比率、骨折部の骨癒合が得られていない偽関節になる割合が有意に高いことが判明した。

  • 【理由がわかる!整形外科のNGケアとOKケア】腰椎術後のNGケアとOKケア Reviewed

    寺井 秀富

    整形外科看護   17 ( 1 )   30 - 35   2012.01( ISSN:1342-4718

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  • Skill Up 最新・手術手技講座(第21回) 内視鏡とバルーンを用いた椎体形成術 Reviewed

    寺井 秀富

    Arthritis-運動器疾患と炎症-   9 ( 3 )   242 - 247   2011.12( ISSN:1348-270X

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  • ウェアラブル加速度計を用いた歩行時動揺測定と頸椎疾患患者の歩行能力評価 Reviewed

    赤松 波子, 今久保 伸二, 加藤 良一, 三好 隆志, 中土 保, 中島 重義, 岩城 啓好, 池渕 充彦, 寺井 秀富, 中村 博亮

    日本臨床バイオメカニクス学会 臨床バイオメカニクス   32   149 - 154   2011.10( ISSN:1884-5274

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    頸椎疾患患者の歩行不安定性を評価するにあたって、ウェアラブル加速度計を用いた歩行時動揺評価が臨床において有用か検討した。頸椎疾患で手術を施行した33例を対象とした。下肢JOA scoreは、重症群では有意に改善し、その後は術後12ヵ月まで有意な変化を認めなかった。軽症群では術前から術後12ヵ月まで有意な変化を認めなかった。静止時動揺は、両群とも術前から術後1ヵ月にかけて動揺が減少する傾向がみられ、どの時期においても正常範囲より動揺は増加した。歩行時動揺は、重症群では有意に減少し、術後歩行自立時より術後12ヵ月まで正常範囲内であった。軽症群では術前から正常範囲内で有意な変化は認めなかった。下肢JOA scoreと静止時動揺・歩行時動揺に相関を認めた。重心動揺計を用いた静止時動揺測定(静的評価)およびウェアラブル加速度計を用いた歩行時動揺測定(動的評価)はそれぞれ臨床的に有用であると示された。

  • ウェアラブル加速度計を用いた歩行時動揺測定と頸椎疾患患者の歩行能力評価 Reviewed

    赤松 波子, 今久保 伸二, 加藤 良一, 三好 隆志, 中土 保, 中島 重義, 岩城 啓好, 池渕 充彦, 寺井 秀富, 中村 博亮

    臨床バイオメカニクス   32   149 - 154   2011.10( ISSN:1884-5274

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    頸椎疾患患者の歩行不安定性を評価するにあたって、ウェアラブル加速度計を用いた歩行時動揺評価が臨床において有用か検討した。頸椎疾患で手術を施行した33例を対象とした。下肢JOA scoreは、重症群では有意に改善し、その後は術後12ヵ月まで有意な変化を認めなかった。軽症群では術前から術後12ヵ月まで有意な変化を認めなかった。静止時動揺は、両群とも術前から術後1ヵ月にかけて動揺が減少する傾向がみられ、どの時期においても正常範囲より動揺は増加した。歩行時動揺は、重症群では有意に減少し、術後歩行自立時より術後12ヵ月まで正常範囲内であった。軽症群では術前から正常範囲内で有意な変化は認めなかった。下肢JOA scoreと静止時動揺・歩行時動揺に相関を認めた。重心動揺計を用いた静止時動揺測定(静的評価)およびウェアラブル加速度計を用いた歩行時動揺測定(動的評価)はそれぞれ臨床的に有用であると示された。

  • Characteristic Radiographic or Magnetic Resonance Images of Fresh Osteoporotic Vertebral Fractures Predicting Potential Risk for Nonunion Reviewed

    Tsujio Tadao, Nakamura Hiroaki, Terai Hidetomi, Hoshino Masatoshi, Namikawa Takashi, Matsumura Akira, Kato Minori, Suzuki Akinobu, Takayama Kazushi, Fukushima Wakaba, Kondo Kyoko, Hirota Yoshio, Takaoka Kunio

    SPINE   36 ( 15 )   1229 - 1235   2011.07( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e3181f29e8d

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  • Characteristic Radiographic or Magnetic Resonance Images of Fresh Osteoporotic Vertebral Fractures Predicting Potential Risk for Nonunion : A Prospective Multicenter Study Reviewed

    TSUJIO Tadao, NAKAMURA Hiroaki, TERAI Hidetomi, HOSHINO Masatoshi, NAMIKAWA Takashi, MATSUMURA Akira, KATO Minori, SUZUKI Akinobu, TAKAYAMA Kazushi, FUKUSHIMA Wakaba, KONDO Kyoko, HIROTA Yoshio, TAKAOKA Kunio

    Spine   36 ( 15 )   1229 - 1235   2011.07( ISSN:03622436

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  • Characteristic Radiographic or Magnetic Resonance Images of Fresh Osteoporotic Vertebral Fractures Predicting Potential Risk for Nonunion : A Prospective Multicenter Study Reviewed

    TSUJIO Tadao, NAKAMURA Hiroaki, TERAI Hidetomi, HOSHINO Masatoshi, NAMIKAWA Takashi, MATSUMURA Akira, KATO Minori, SUZUKI Akinobu, TAKAYAMA Kazushi, FUKUSHIMA Wakaba, KONDO Kyoko, HIROTA Yoshio, TAKAOKA Kunio

    Spine (Phila Pa 1976)   36 ( 15 )   1229 - 1235   2011.07( ISSN:03622436

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  • Characteristic radiographic or magnetic resonance images of fresh osteoporotic vertebral fractures predicting potential risk for nonunion: a prospective multicenter study. Reviewed

    Tsujio T, Nakamura H, Terai H, Hoshino M, Namikawa T, Matsumura A, Kato M, Suzuki A, Takayama K, Fukushima W, Kondo K, Hirota Y, Takaoka K

    Spine   36 ( 15 )   1229 - 35   2011.07( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e3181f29e8d

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  • 【頸椎神経根症に対する手術的治療】頸椎症性神経根症に対する顕微鏡視下key hole foraminotomy Reviewed

    寺井 秀富, 鈴木 亨暢, 豊田 宏光, 中村 博亮, 金田 国一, 谷内 政俊

    整形・災害外科   54 ( 6 )   679 - 685   2011.05( ISSN:0387-4095

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  • Bronchoscopic microsampling is a useful complementary diagnostic tool for detecting lung cancer. Reviewed

    Yasuda H, Soejima K, Nakayama S, Kawada I, Nakachi I, Yoda S, Satomi R, Ikemura S, Terai H, Sato T, Watanabe H, Naoki K, Hayashi Y, Ishizaka A

    Lung cancer (Amsterdam, Netherlands)   72 ( 1 )   32 - 8   2011.04( ISSN:0169-5002

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    DOI: 10.1016/j.lungcan.2010.07.016

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  • A phase I study of S-1 and irinotecan combination therapy in previously treated advanced non-small cell lung cancer patients. Reviewed

    Yoda S, Soejima K, Yasuda H, Naoki K, Kawada I, Watanabe H, Nakachi I, Satomi R, Nakayama S, Ikemura S, Terai H, Sato T, Morosawa M, Asano K

    Cancer chemotherapy and pharmacology   67 ( 3 )   717 - 22   2011.03( ISSN:0344-5704

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    DOI: 10.1007/s00280-010-1539-y

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  • Risk Factor Analysis for Motor Deficit and Delayed Recovery Associated With L4/5 Lumbar Disc Herniation Reviewed

    Suzuki Akinobu, Matsumura Akira, Konishi Sadahiko, Terai Hidetomi, Tsujio Tadao, Dozono Sho, Nakamura Hiroaki

    JOURNAL OF SPINAL DISORDERS & TECHNIQUES   24 ( 1 )   1 - 5   2011.02( ISSN:1536-0652

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    DOI: 10.1097/BSD.0b013e3181c5be1d

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  • 骨粗鬆症性脊椎骨折後骨癒合不全患者の神経学的欠損に影響を及ぼす因子(Factors Affecting Neurological Deficits in Patients with Insufficient Bone Union following Osteoporotic Vertebral Fracture) Reviewed

    Hoshino Masatoshi, Nakamura Hiroaki, Terai Hidetomi, Tsujio Tadao, Nabeta Masaharu, Namikawa Takashi, Matsumura Akira, Suzuki Akinobu, Takayama Kazushi, Takaoka Kunio

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   2 ( 2 )   319 - 323   2011.02( ISSN:1884-7137

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    骨粗鬆症性脊椎骨折(OVF)は通常数ヵ月以内に自然治癒するが、難治性の腰痛や神経学的欠損がみられる症例が存在する。これら患者では骨癒合不全がしばしばみられる。単純X線撮影またはCTおよびMRI T2強調像で骨癒合不全と診断されたOVF患者45名(男10名、女35名、56〜87歳)を対象として、神経学的欠損の有無を徒手筋力テストで調べた。骨折の部位はT9 1名、T11 3名、T12 22名、L1 11名、L2 6名、L4 1名、L5 1名であった。その結果、21名(46.7%)で軽度または重度神経学的欠損が認められた。神経学的欠損は骨折のみられた椎体において15°以上の角不安定性がみられた患者と骨片による脊柱管占拠率が42%以上の患者で多く認められた。神経学的欠損に対しては神経除圧を行わずに骨折した脊椎を安定化させることが重要である。骨侵入率が高い患者に対しては除圧術が必要となるかもしれない。

  • Risk factor analysis for motor deficit and delayed recovery associated with L4/5 lumbar disc herniation. Reviewed

    Suzuki A, Matsumura A, Konishi S, Terai H, Tsujio T, Dozono S, Nakamura H

    Journal of spinal disorders & techniques   24 ( 1 )   1 - 5   2011.02( ISSN:1536-0652

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    DOI: 10.1097/BSD.0b013e3181c5be1d

    PubMed

  • 骨粗鬆症性脊椎骨折後骨癒合不全患者の神経学的欠損に影響を及ぼす因子(Factors Affecting Neurological Deficits in Patients with Insufficient Bone Union following Osteoporotic Vertebral Fracture) Reviewed

    Hoshino Masatoshi, Nakamura Hiroaki, Terai Hidetomi, Tsujio Tadao, Nabeta Masaharu, Namikawa Takashi, Matsumura Akira, Suzuki Akinobu, Takayama Kazushi, Takaoka Kunio

    Journal of Spine Research   2 ( 2 )   319 - 323   2011.02( ISSN:1884-7137

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    骨粗鬆症性脊椎骨折(OVF)は通常数ヵ月以内に自然治癒するが、難治性の腰痛や神経学的欠損がみられる症例が存在する。これら患者では骨癒合不全がしばしばみられる。単純X線撮影またはCTおよびMRI T2強調像で骨癒合不全と診断されたOVF患者45名(男10名、女35名、56〜87歳)を対象として、神経学的欠損の有無を徒手筋力テストで調べた。骨折の部位はT9 1名、T11 3名、T12 22名、L1 11名、L2 6名、L4 1名、L5 1名であった。その結果、21名(46.7%)で軽度または重度神経学的欠損が認められた。神経学的欠損は骨折のみられた椎体において15°以上の角不安定性がみられた患者と骨片による脊柱管占拠率が42%以上の患者で多く認められた。神経学的欠損に対しては神経除圧を行わずに骨折した脊椎を安定化させることが重要である。骨侵入率が高い患者に対しては除圧術が必要となるかもしれない。

  • The influence of approach side on facet preservation in microscopic bilateral decompression via a unilateral approach for degenerative lumbar scoliosis Reviewed

    Matsumura Akira, Namikawa Takashi, Terai Hidetomi, Tsujio Tadao, Suzuki Akinobu, Dozono Sho, Yasuda Hiroyuki, Nakamura Hiroaki

    JOURNAL OF NEUROSURGERY-SPINE   13 ( 6 )   758 - 765   2010.12( ISSN:1547-5654

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    DOI: 10.3171/2010.5.SPINE091001

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  • Distinct epigenetic regulation of tumor suppressor genes in putative cancer stem cells of solid tumors. Reviewed

    Yasuda H, Soejima K, Watanabe H, Kawada I, Nakachi I, Yoda S, Nakayama S, Satomi R, Ikemura S, Terai H, Sato T, Suzuki S, Matsuzaki Y, Naoki K, Ishizaka A

    International journal of oncology   37 ( 6 )   1537 - 46   2010.12( ISSN:1019-6439

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    DOI: 10.3892/ijo_00000807

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  • The influence of approach side on facet preservation in microscopic bilateral decompression via a unilateral approach for degenerative lumbar scoliosis. Clinical article. Reviewed

    Matsumura A, Namikawa T, Terai H, Tsujio T, Suzuki A, Dozono S, Yasuda H, Nakamura H

    Journal of neurosurgery. Spine   13 ( 6 )   758 - 65   2010.12( ISSN:1547-5654

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    DOI: 10.3171/2010.5.SPINE091001

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  • 長寿フロントライン 骨粗鬆性椎体骨折の治療成績不良をもたらす因子の解明と効果的かつ効率的な治療法の確立 Reviewed

    寺井 秀富

    Aging & Health   19 ( 3 )   38 - 39   2010.10

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  • Clinical Results of Microendoscopic Translaminar Approach for Upper Migrated Lumber Disc Herniation Reviewed

    KANEDA Kunikazu, YOSHIDA Gen, MATSUURA Takeshi, TOMIHARA Tomohiro, SHIMADA Nagakazu, TERAI Hidetomi

    Journal of spine research   1 ( 9 )   1700 - 1704   2010.09( ISSN:18847137

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    CiNii Article

  • Assessment of Gait in Patients with Neck Disease Using a Wearable Accelerometer Reviewed

    AKAMATSU Namiko, IMAKUBO Shinji, KATO Ryoichi, MIYOSHI Takashi, NAKATSUCHI Tamotsu, NAKAJIMA Shigeyoshi, IWAKI Hiroyoshi, IKEBUCHI Mitsuhiko, TERAI Hidetomi, NAKAMURA Hiroaki

    Japanese journal of clinical biomechanics   31   85 - 90   2010.09( ISSN:18845274

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    CiNii Article

  • ウェアラブル加速度計を用いた頸椎疾患患者の歩行評価 Reviewed

    赤松 波子, 今久保 伸二, 加藤 良一, 三好 隆志, 中土 保, 中島 重義, 岩城 啓好, 池渕 充彦, 寺井 秀富, 中村 博亮

    日本臨床バイオメカニクス学会 臨床バイオメカニクス   31   85 - 90   2010.09( ISSN:1884-5274

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    頸椎手術前後の歩行における不安定性を簡便かつ客観的に評価する方法とし歩行リズムに着目し、ウェアラブル加速度計で測定したデータを離散コサイン変換(DCT)解析し、これにBand pass filterの手法を加えてピーク占有率を求めることで定量化を試みた。頸椎疾患で手術施行した37例および健常者10例を対象とした。術前JOA scoreの下肢運動機能点数で群分けし、重症群27例、軽症群10例であった。健常者のピーク占有率は0.64±0.07で、これを健常モデルとした。術前、重症群のピーク占有率は健常モデルに比べて低く、軽症群は健常モデルとほぼ同じ値であった。重症群のピーク占有率は、術前に比べ術後1ヵ月、術後3ヵ月で有意に増加し、健常モデルに近づいた。軽症群においてはいずれの時期でも有意な変化を認めなかった。

  • Upper migratedヘルニアに対する内視鏡下経椎弓進入法の治療成績 Reviewed

    金田 国一, 吉田 玄, 松浦 健司, 富原 朋弘, 島田 永和, 寺井 秀富

    (一社)日本脊椎脊髄病学会 Journal of Spine Research   1 ( 9 )   1700 - 1704   2010.09( ISSN:1884-7137

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    脊柱管内にupper migrateした腰椎椎間板ヘルニアを摘出する際、下関節突起骨折の危険性を回避するため、椎弓に約10mmの骨孔を開け、経椎弓的にヘルニアを摘出する内視鏡下経椎弓進入法を行った。2008年8月以降の1年間に、当院で同法を行った7症例(男6例、女1例)を対象とした。手術時平均年齢は56歳(42〜68歳)、ヘルニア高位は、L3/4 3例、L4/5 4例であった。骨孔の幅は平均10.9mm(8.9〜11.2mm)、骨孔と椎弓下縁の距離は平均8.1mm(4.2〜11.9mm)であった。手術時間は平均62分(36〜84分)、JOA scoreの平均改善率は83%と良好であった。本法は、従来法に較べ、(1)骨切除量が少なく、下関節突起骨折の危険が少ない。(2)組織侵襲が少ない、などの利点がある。骨孔内に斜視鏡を挿入することで硬膜外腔を広く見渡すことができ、内視鏡の特徴をいかした手術方法であると考えられる。(著者抄録)

  • Upper migratedヘルニアに対する内視鏡下経椎弓進入法の治療成績 Reviewed

    金田 国一, 吉田 玄, 松浦 健司, 富原 朋弘, 島田 永和, 寺井 秀富

    Journal of Spine Research   1 ( 9 )   1700 - 1704   2010.09( ISSN:1884-7137

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    脊柱管内にupper migrateした腰椎椎間板ヘルニアを摘出する際、下関節突起骨折の危険性を回避するため、椎弓に約10mmの骨孔を開け、経椎弓的にヘルニアを摘出する内視鏡下経椎弓進入法を行った。2008年8月以降の1年間に、当院で同法を行った7症例(男6例、女1例)を対象とした。手術時平均年齢は56歳(42〜68歳)、ヘルニア高位は、L3/4 3例、L4/5 4例であった。骨孔の幅は平均10.9mm(8.9〜11.2mm)、骨孔と椎弓下縁の距離は平均8.1mm(4.2〜11.9mm)であった。手術時間は平均62分(36〜84分)、JOA scoreの平均改善率は83%と良好であった。本法は、従来法に較べ、(1)骨切除量が少なく、下関節突起骨折の危険が少ない。(2)組織侵襲が少ない、などの利点がある。骨孔内に斜視鏡を挿入することで硬膜外腔を広く見渡すことができ、内視鏡の特徴をいかした手術方法であると考えられる。(著者抄録)

  • ウェアラブル加速度計を用いた頸椎疾患患者の歩行評価 Reviewed

    赤松 波子, 今久保 伸二, 加藤 良一, 三好 隆志, 中土 保, 中島 重義, 岩城 啓好, 池渕 充彦, 寺井 秀富, 中村 博亮

    臨床バイオメカニクス   31   85 - 90   2010.09( ISSN:1884-5274

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    頸椎手術前後の歩行における不安定性を簡便かつ客観的に評価する方法とし歩行リズムに着目し、ウェアラブル加速度計で測定したデータを離散コサイン変換(DCT)解析し、これにBand pass filterの手法を加えてピーク占有率を求めることで定量化を試みた。頸椎疾患で手術施行した37例および健常者10例を対象とした。術前JOA scoreの下肢運動機能点数で群分けし、重症群27例、軽症群10例であった。健常者のピーク占有率は0.64±0.07で、これを健常モデルとした。術前、重症群のピーク占有率は健常モデルに比べて低く、軽症群は健常モデルとほぼ同じ値であった。重症群のピーク占有率は、術前に比べ術後1ヵ月、術後3ヵ月で有意に増加し、健常モデルに近づいた。軽症群においてはいずれの時期でも有意な変化を認めなかった。

  • A prospective multicenter registry of 0.010-inch guidewire and compatible system for chronic total occlusion: the PIKACHU registry. Reviewed

    Matsukage T, Masutani M, Yoshimachi F, Takahashi A, Katsuki T, Saito S, Terai H, Katahira Y, Uehara Y, Tohara S, Ohba Y, Shinohara S, Asano H, Matsumura T, Hata T, Ikari Y, PIKACHU Registry Investigators.

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions   75 ( 7 )   1006 - 12   2010.06( ISSN:1522-1946

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    DOI: 10.1002/ccd.22434

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  • Chronic oral ulcer associated with Candida. Reviewed

    Terai H, Shimahara M

    Mycoses   53 ( 2 )   168 - 72   2010.03( ISSN:0933-7407

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    DOI: 10.1111/j.1439-0507.2008.01675.x

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  • Assessment of Gaiting Body Sway in Patients with Neck Disease Pre and Post-operation Reviewed

    AKAMATSU Namiko, IMAKUBO Shinji, KATO Ryoichi, NAKATSUCHI Tamotsu, NAKAJIMA Shigeyoshi, IWAKI Hiroyoshi, IKEBUCHI Mitsuhiko, TERAI Hidetomi, TAKAOKA Kunio

    Japanese journal of clinical biomechanics   30   161 - 166   2009.09( ISSN:18845274

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  • 腰部脊柱管狭窄症に対する手術侵襲度の比較(内視鏡下手術vs顕微鏡視下手術) Reviewed

    寺井 秀富, 中村 博亮

    整形外科   60 ( 10 )   1072 - 1072   2009.09( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j00764.2009320271

  • Factors affecting neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture Reviewed

    Hoshino Masatoshi, Nakamura Hiroaki, Terai Hidetomi, Tsujio Tadao, Nabeta Masaharu, Namikawa Takashi, Matsumura Akira, Suzuki Akinobu, Takayama Kazushi, Takaoka Kunio

    EUROPEAN SPINE JOURNAL   18 ( 9 )   1279 - 1286   2009.09( ISSN:0940-6719

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    DOI: 10.1007/s00586-009-1041-6

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  • 頸椎手術前後における歩行時の身体動揺の評価 ウェアラブル加速度計と重心動揺計を用いた検討 Reviewed

    赤松 波子, 今久保 伸二, 加藤 良一, 中土 保, 中島 重義, 岩城 啓好, 池渕 充彦, 寺井 秀富, 高岡 邦夫

    日本臨床バイオメカニクス学会 臨床バイオメカニクス   30   161 - 166   2009.09( ISSN:1884-5274

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    頸椎手術前後の歩行における不安定性を簡便かつ客観的に評価する方法の検討とし、ウェアラブル加速度計による歩行時の身体動揺(歩行時動揺)測定と重心動揺計による静止立位時の足圧中心動揺(静止時動揺)測定とを比較・検討した。頸椎疾患を有し、手術施行した44例を対象とした。術前の動揺比較では、軽症群に対して重症群は左右・前後・上下方向の歩行時動揺および静止時動揺すべての項目で有意に動揺が増加した。術後早期の歩行不安定性を客観的に評価するには重心動揺計による静的評価のみでは不十分で、実際の歩行を動的に評価することが必要であると示唆された。ウェアラブル加速度計は三次元動作解析器のように詳細な解析は困難であるが、簡便、測定条件の自由度が高いなどの利点があった。ウェアラブル加速度計による動的評価が従来定量化困難であった術後早期の歩行不安定性を簡便かつ客観的に評価できる方法であることが示唆された。

  • 腰部脊柱管狭窄症に対する手術侵襲度の比較(内視鏡下手術vs顕微鏡視下手術) Reviewed

    寺井 秀富, 中村 博亮

    (株)南江堂 整形外科   60 ( 10 )   1072 - 1072   2009.09( ISSN:0030-5901

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  • Factors affecting neurological deficits and intractable back pain in patients with insufficient bone union following osteoporotic vertebral fracture. Reviewed

    Hoshino M, Nakamura H, Terai H, Tsujio T, Nabeta M, Namikawa T, Matsumura A, Suzuki A, Takayama K, Takaoka K

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   18 ( 9 )   1279 - 86   2009.09( ISSN:0940-6719

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    DOI: 10.1007/s00586-009-1041-6

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  • 腰部脊柱管狭窄症に対する手術侵襲度の比較(内視鏡下手術vs顕微鏡視下手術) Reviewed

    寺井 秀富, 中村 博亮

    整形外科   60 ( 10 )   1072 - 1072   2009.09( ISSN:0030-5901

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  • 頸椎手術前後における歩行時の身体動揺の評価 ウェアラブル加速度計と重心動揺計を用いた検討 Reviewed

    赤松 波子, 今久保 伸二, 加藤 良一, 中土 保, 中島 重義, 岩城 啓好, 池渕 充彦, 寺井 秀富, 高岡 邦夫

    臨床バイオメカニクス   30   161 - 166   2009.09( ISSN:1884-5274

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    頸椎手術前後の歩行における不安定性を簡便かつ客観的に評価する方法の検討とし、ウェアラブル加速度計による歩行時の身体動揺(歩行時動揺)測定と重心動揺計による静止立位時の足圧中心動揺(静止時動揺)測定とを比較・検討した。頸椎疾患を有し、手術施行した44例を対象とした。術前の動揺比較では、軽症群に対して重症群は左右・前後・上下方向の歩行時動揺および静止時動揺すべての項目で有意に動揺が増加した。術後早期の歩行不安定性を客観的に評価するには重心動揺計による静的評価のみでは不十分で、実際の歩行を動的に評価することが必要であると示唆された。ウェアラブル加速度計は三次元動作解析器のように詳細な解析は困難であるが、簡便、測定条件の自由度が高いなどの利点があった。ウェアラブル加速度計による動的評価が従来定量化困難であった術後早期の歩行不安定性を簡便かつ客観的に評価できる方法であることが示唆された。

  • Repair of long intercalated rib defects in dogs using recombinant human bone morphogenetic protein-2 delivered by a synthetic polymer and beta-tricalcium phosphate Reviewed

    Hoshino Masatoshi, Egi Takeshi, Terai Hidetomi, Namikawa Takashi, Kato Minori, Hashimoto Yusuke, Takaoka Kunio

    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A   90A ( 2 )   514 - 521   2009.08( ISSN:1549-3296

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    DOI: 10.1002/jbm.a.32123

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  • Repair of long intercalated rib defects in dogs using recombinant human bone morphogenetic protein-2 delivered by a synthetic polymer and beta-tricalcium phosphate. Reviewed

    Hoshino M, Egi T, Terai H, Namikawa T, Kato M, Hashimoto Y, Takaoka K

    Journal of biomedical materials research. Part A   90 ( 2 )   514 - 21   2009.08( ISSN:1549-3296

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    DOI: 10.1002/jbm.a.32123

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  • Chronic tongue ulceration resolved by sulpiride: a report of two cases. Reviewed

    Terai H, Shimahara M

    Clinical and experimental dermatology   34 ( 5 )   e40 - 2   2009.07( ISSN:0307-6938

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    DOI: 10.1111/j.1365-2230.2008.03110.x

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  • 骨粗鬆症性脊椎骨折の治療 骨粗鬆症性椎体骨折偽関節発生の予測因子 Reviewed

    中村 博亮, 辻尾 唯雄, 寺井 秀富, 星野 雅俊, 豊田 宏光, 鈴木 亨暢, 伊達 優子, 高岡 邦夫

    ライフサイエンス出版(株) Osteoporosis Japan   17 ( 2 )   177 - 181   2009.04( ISSN:0919-6307

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    大阪市立大学整形外科関連25施設に登録され、6ヵ月間の経過観察を終了した新鮮骨粗鬆症性椎体骨折280例を対象に、偽関節の発生率と偽関節発生を予測する受傷時の画像的因子について検討した。内訳は男性43例、女性237例で、平均年齢は75.9歳であった。その結果、6ヵ月後の偽関節発生率は12.7%(37例)であった。6ヵ月後の偽関節を目的変数とした多変量解析の結果、胸腰椎移行部の骨折、MRI T2強調画像における高輝度限局性変化、広範な低輝度性変化が、偽関節発生を予測させる受傷時の画像的変化であることが判明した。

  • 骨粗鬆症性脊椎骨折の治療 骨粗鬆症性椎体骨折偽関節発生の予測因子 Reviewed

    中村 博亮, 辻尾 唯雄, 寺井 秀富, 星野 雅俊, 豊田 宏光, 鈴木 亨暢, 伊達 優子, 高岡 邦夫

    Osteoporosis Japan   17 ( 2 )   177 - 181   2009.04( ISSN:0919-6307

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    大阪市立大学整形外科関連25施設に登録され、6ヵ月間の経過観察を終了した新鮮骨粗鬆症性椎体骨折280例を対象に、偽関節の発生率と偽関節発生を予測する受傷時の画像的因子について検討した。内訳は男性43例、女性237例で、平均年齢は75.9歳であった。その結果、6ヵ月後の偽関節発生率は12.7%(37例)であった。6ヵ月後の偽関節を目的変数とした多変量解析の結果、胸腰椎移行部の骨折、MRI T2強調画像における高輝度限局性変化、広範な低輝度性変化が、偽関節発生を予測させる受傷時の画像的変化であることが判明した。

  • 【骨粗鬆症性脊椎骨折 診断、治療の最前線】骨粗鬆症性椎体骨折偽関節発生の予測因子 Reviewed

    中村 博亮, 辻尾 唯雄, 寺井 秀富, 星野 雅俊, 高岡 邦夫

    (株)三輪書店 脊椎脊髄ジャーナル   22 ( 3 )   240 - 246   2009.03( ISSN:0914-4412

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    椎体骨折後における偽関節の発生率と偽関節発生を予測するため、大阪府下の関連25施設において、6ヵ月間の観察期間を有する前向きコ-ホ-ト研究を行った。研究対象は、65歳以上の新鮮骨粗鬆症性椎体骨折例280例291椎体で、男性43例、女性237例、登録時平均75.9歳であった。研究の結果、6ヵ月の経過観察において、骨粗鬆症性椎体骨折の後、偽関節が発生する頻度は12.7%であった。偽関節例は、骨癒合例に比較して、寝たきりになる症例数比率、ADLの低下する症例比率、高度疼痛が遷延する症例比率が高く、その経過はより不良であった。また、偽関節発生を予測させる受傷時の画像的変化として、胸腰椎移行部の骨折、T2強調像における高輝度限局性変化、広範な低輝度性変化が有効であった。

  • 【骨粗鬆症性脊椎骨折 診断、治療の最前線】骨粗鬆症性椎体骨折偽関節発生の予測因子 Reviewed

    中村 博亮, 辻尾 唯雄, 寺井 秀富, 星野 雅俊, 高岡 邦夫

    脊椎脊髄ジャーナル   22 ( 3 )   240 - 246   2009.03( ISSN:0914-4412

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    椎体骨折後における偽関節の発生率と偽関節発生を予測するため、大阪府下の関連25施設において、6ヵ月間の観察期間を有する前向きコ-ホ-ト研究を行った。研究対象は、65歳以上の新鮮骨粗鬆症性椎体骨折例280例291椎体で、男性43例、女性237例、登録時平均75.9歳であった。研究の結果、6ヵ月の経過観察において、骨粗鬆症性椎体骨折の後、偽関節が発生する頻度は12.7%であった。偽関節例は、骨癒合例に比較して、寝たきりになる症例数比率、ADLの低下する症例比率、高度疼痛が遷延する症例比率が高く、その経過はより不良であった。また、偽関節発生を予測させる受傷時の画像的変化として、胸腰椎移行部の骨折、T2強調像における高輝度限局性変化、広範な低輝度性変化が有効であった。

  • 腰部脊柱管狭窄症における手術侵襲に対する臨床的前向き研究 内視鏡下後方除圧と顕微鏡下後方除圧間の比較(A Clinical Prospective Study on the Operative Invasion for Lumbar Spinal Canal Stenosis: A Comparison between Microendoscopic and Microscopic Posterior Decompression) Reviewed

    Terai Hidetomi, Suzuki Akinobu, Tsujio Tadao, Matsumura Akira, Douzono Shou, Maeno Takashi, Takayama Kazushi, Toyoda Hiromitsu, Nakamura Hiroaki, Takaoka Kunio

    (一社)日本脊椎脊髄病学会 日本脊椎脊髄病学会雑誌   19 ( 3 )   609 - 612   2008.11( ISSN:1346-4876

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    腰部脊柱管狭窄症患者22例を、顕微鏡下(Micro)群(平均68.6歳)13例と、内視鏡下(MEPD)群(同71.6歳)9例に分けて、両群共に片側進入両側除圧を行い検討した。その結果、Micro群、MEPD群において、術後、術後12ヵ月のJOAスコア及び腰痛に関して、視覚的アナログ尺度に有意差は認められなかった。平均手術時間、1レベル毎の調整後手術時間、出血量、術後鎮痛剤使用頻度、CRP、IL-6値に有意差は認められなかった。3)CRPは術後3日にピークを迎え、7日以内に術前値に戻った。以上より、内視鏡下後方除圧と顕微鏡下後方除圧の2方法は、手術成績と同様に手術侵襲性に関しても同等であることが示された。

  • 腰部脊柱管狭窄症における手術侵襲に対する臨床的前向き研究 内視鏡下後方除圧と顕微鏡下後方除圧間の比較(A Clinical Prospective Study on the Operative Invasion for Lumbar Spinal Canal Stenosis: A Comparison between Microendoscopic and Microscopic Posterior Decompression) Reviewed

    Terai Hidetomi, Suzuki Akinobu, Tsujio Tadao, Matsumura Akira, Douzono Shou, Maeno Takashi, Takayama Kazushi, Toyoda Hiromitsu, Nakamura Hiroaki, Takaoka Kunio

    日本脊椎脊髄病学会雑誌   19 ( 3 )   609 - 612   2008.11( ISSN:1346-4876

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    腰部脊柱管狭窄症患者22例を、顕微鏡下(Micro)群(平均68.6歳)13例と、内視鏡下(MEPD)群(同71.6歳)9例に分けて、両群共に片側進入両側除圧を行い検討した。その結果、Micro群、MEPD群において、術後、術後12ヵ月のJOAスコア及び腰痛に関して、視覚的アナログ尺度に有意差は認められなかった。平均手術時間、1レベル毎の調整後手術時間、出血量、術後鎮痛剤使用頻度、CRP、IL-6値に有意差は認められなかった。3)CRPは術後3日にピークを迎え、7日以内に術前値に戻った。以上より、内視鏡下後方除圧と顕微鏡下後方除圧の2方法は、手術成績と同様に手術侵襲性に関しても同等であることが示された。

  • Why does delay exist in the diagnosis of intradural spinal cord tumor despite the availability of MRI? Reviewed

    Kato Minori, Nakamura Hiroaki, Terai Hidetomi, Konishi Sadahiko, Nagayama Ryuichi, Takaoka Kunio

    JOURNAL OF CLINICAL NEUROSCIENCE   15 ( 8 )   880 - 885   2008.08( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2007.03.019

    PubMed

  • Why does delay exist in the diagnosis of intradural spinal cord tumor despite the availability of MRI? Reviewed

    Kato M, Nakamura H, Terai H, Konishi S, Nagayama R, Takaoka K

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   15 ( 8 )   880 - 5   2008.08( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2007.03.019

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  • Ependymal cyst in the lumbar spine associated with cauda equina compression Reviewed

    Kato Minori, Nakamura Hiroaki, Suzuki Eisuke, Terai Hidetomi, Wakasa Kenichi, Wakasa Tomoko, Takaoka Kunio

    JOURNAL OF CLINICAL NEUROSCIENCE   15 ( 7 )   827 - 830   2008.07( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2006.12.020

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  • Ependymal cyst in the lumbar spine associated with cauda equina compression. Reviewed

    Kato M, Nakamura H, Suzuki E, Terai H, Wakasa K, Wakasa T, Takaoka K

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   15 ( 7 )   827 - 30   2008.07( ISSN:0967-5868

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    DOI: 10.1016/j.jocn.2006.12.020

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  • 脊椎・末梢神経の成長・発達 Reviewed

    寺井 秀富

    バイオメカニズム学会 バイオメカニズム学会誌 = Journal of the Society of Biomechanisms   32 ( 2 )   65 - 68   2008.05( ISSN:02850885

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    体を動かすということは,筋を収縮させて体の関節を動かすということに他ならない.そのためには中枢神経で生じた命令が電気的信号として末梢神経を経て筋に達し,最終的に筋の収縮が起こるという一連のメカニズムが働いている.これら運動神経-筋の関係は胎生期に形成され,その関係を保ったまま成長し終生変わることがない.そのため,末梢神経-筋の情報伝達メカニズムを理解するためには胎生期での神経,筋の発生に関する知識が必要となる.本稿では,末梢神経,筋の発生と神経の構造についての解説を加え,2次ニューロンレベルでの神経支配メカニズムの形成に着目して解説する.

    DOI: 10.3951/sobim.32.65

    CiNii Article

  • Thoracic epidural and intradural meningioma with calcification ; A case report Reviewed

    MAENO Takafumi

    51 ( 3 )   397 - 399   2008.05( ISSN:00089443

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    CiNii Article

  • 【成長・発達のバイオメカニズム】脊椎・末梢神経の成長・発達 Reviewed

    寺井 秀富

    バイオメカニズム学会誌   32 ( 2 )   65 - 68   2008.05( ISSN:0285-0885

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    体を動かすということは、筋を収縮させて体の関節を動かすということに他ならない。そのためには中枢神経で生じた命令が電気的信号として末梢神経を経て筋に達し、最終的に筋の収縮が起こるという一連のメカニズムが働いている。これら運動神経-筋の関係は胎生期に形成され、その関係を保ったまま成長し終生変わることがない。そのため、末梢神経-筋の情報伝達メカニズムを理解するためには胎生期での神経、筋の発生に関する知識が必要となる。本稿では、末梢神経、筋の発生と神経の構造についての解説を加え、2次ニューロンレベルでの神経支配メカニズムの形成に着目して解説する。(著者抄録)

  • 硬膜内外に存在した石灰化を伴った胸椎髄膜腫の1例 Reviewed

    前野 考史, 松村 昭, 中村 博亮, 辻尾 唯雄, 寺井 秀富, 月山 国明, 高岡 邦夫

    中部日本整形外科災害外科学会雑誌   51 ( 3 )   397 - 399   2008.05( ISSN:0008-9443

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    68歳女。左側腹痛と左優位の両下肢痛・痺れを主訴とした。単純レントゲンで脊柱管内の硬化像を認め、MRIではTh10レベル脊柱管内にT1強調像で低〜等信号、T2強調像で低信号、ガドリニウム造影で不均一に造影される腫瘍を認めた。石灰化を伴う硬膜内髄外腫瘍、特に髄膜腫を疑い、胸椎後方進入により腫瘍摘出術を施行した。腫瘍は硬膜を含め完全切除し、硬膜欠損部には右外側広筋より筋膜を採取し硬膜形成を施行した。病理組織学的所見では腫瘍組織の大部分を砂粒体が占め、砂粒体は硬膜内の腫瘍部分に多く見られた。また、楕円形で淡色の核を持つ紡錘形の異型細胞が、細胞間線維化を伴い増殖しており、移行性〜砂粒腫性髄膜腫と診断した。術後経過は良好で、術後3ヵ月の現在、両足趾の痺れは残存しているが、腫瘍の再発は認めていない。

  • Prognostic Factors on Pseudoarthrosis Following Osteoporotic Vertebral Fractures: Prospective Multicenter Study Reviewed

    43 ( 4 )   309 - 314   2008.04( ISSN:05570433 ( eISSN:18821286

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    DOI: 10.11477/mf.1408101256

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  • 骨粗鬆症性脊椎骨折の病態 骨粗鬆症性椎体骨折後偽関節発生に関与する予後不良因子について 多施設前向きコーホート研究 Reviewed

    中村 博亮, 辻尾 唯雄, 寺井 秀富, 星野 雅俊, 松村 昭, 加藤 相勲, 鈴木 亨暢, 高山 和士, 高岡 邦夫

    臨床整形外科   43 ( 4 )   309 - 314   2008.04( ISSN:0557-0433

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    関連27施設において65歳以上の骨粗鬆症性椎体骨折例を登録し,6ヵ月後の予後を検討した.登録時に疼痛部位の単純X線とルーチンMRIを施行した.6ヵ月後に症例を偽関節症例群と骨癒合症例群に分類し,登録時の画像的所見を比較検討した.対象症例は150例で,6ヵ月後のX線像で骨癒合群が129例に,偽関節が21例にみられ,偽関節への移行率は14.0%であった.登録時のMRI T2強調画像で高輝度限局型が最も偽関節への移行率が高く,次いで低輝度広範型が高かった.また椎体後壁損傷がある症例では,ない症例に比較して偽関節へ移行しやすかった.(著者抄録)

  • Result of C3-6 Laminoplasty with PLLA lateral mass screw Reviewed

    MAENO T.

    19 ( 2 )   2008.03( ISSN:13464876

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  • Prognostic evaluatuion of an osteoporotic vertebral fracture by MRI scanned in early stage : prospective multicenter study Reviewed

    TSUJIO T.

    19 ( 2 )   2008.03( ISSN:13464876

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  • A clinical prospective study on the operative invasion for lumbar spinal canal stenosis : comparison between microendoscopic and microscopic posterior decompression Reviewed

    TERAI H.

    19 ( 2 )   2008.03( ISSN:13464876

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  • Risk factor analysis for motor deficits and the late recovery associated with L4/5 lumbar disc herniation Reviewed

    S. Akinobu

    19 ( 2 )   2008.03( ISSN:13464876

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  • Radiographic evaluation of microscopic bilateral decompression via unilateral approach for degenerative lumbar scoliosis Reviewed

    MATSUMURA A.

    19 ( 1 )   2008.03( ISSN:13464876

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  • Clinical results of Unilateral Transforaminal Lumbar Interbody Fusionfor degenerative lumbar scoliosis Reviewed

    HAYAKAWA K.

    19 ( 1 )   2008.03( ISSN:13464876

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  • Radiographic evaluation of the postoperative bone re-growth in bilateral decompression via unilateral approach in degenerative lumbar spondylolisthesis Reviewed

    DOUZONO S.

    19 ( 1 )   2008.03( ISSN:13464876

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  • Low back pain in surgically treated patients with scoliosis : Longer than 15-year follow-up Reviewed

    TAKAYAMA K.

    19 ( 2 )   2008.03( ISSN:13464876

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  • Result of C3-6 Laminoplasty with PLLA lateral mass screw Reviewed

    MAENO T.

    19 ( 2 )   275   2008.03( ISSN:13464876

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  • Low back pain in surgically treated patients with scoliosis : Longer than 15-year follow-up Reviewed

    TAKAYAMA K.

    19 ( 2 )   285   2008.03( ISSN:13464876

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  • Prognostic evaluatuion of an osteoporotic vertebral fracture by MRI scanned in early stage : prospective multicenter study Reviewed

    TSUJIO T.

    19 ( 2 )   374   2008.03( ISSN:13464876

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    CiNii Article

  • A clinical prospective study on the operative invasion for lumbar spinal canal stenosis : comparison between microendoscopic and microscopic posterior decompression Reviewed

    TERAI H.

    19 ( 2 )   220   2008.03( ISSN:13464876

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  • Risk factor analysis for motor deficits and the late recovery associated with L4/5 lumbar disc herniation Reviewed

    S. Akinobu

    19 ( 2 )   311   2008.03( ISSN:13464876

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  • Radiographic evaluation of microscopic bilateral decompression via unilateral approach for degenerative lumbar scoliosis Reviewed

    MATSUMURA A.

    19 ( 1 )   67   2008.03( ISSN:13464876

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  • Clinical results of Unilateral Transforaminal Lumbar Interbody Fusionfor degenerative lumbar scoliosis Reviewed

    HAYAKAWA K.

    19 ( 1 )   56   2008.03( ISSN:13464876

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  • Radiographic evaluation of the postoperative bone re-growth in bilateral decompression via unilateral approach in degenerative lumbar spondylolisthesis Reviewed

    DOUZONO S.

    19 ( 1 )   82   2008.03( ISSN:13464876

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  • Thoracic epidural and intradural meningioma with calcification; A case report Reviewed

    MAENO Takafumi

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   51 ( 3 )   397 - 399   2008

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    DOI: 10.11359/chubu.2008.397

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  • 腰椎変性側弯症に対する顕微鏡視下片側進入両側除圧術の治療成績 Reviewed

    松村 昭, 並川 崇, 寺井 秀富

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会学術集会 抄録集   109 ( 0 )   5 - 5   2008

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    DOI: 10.11359/cjaost.109.0.5.0

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  • 脊椎カリエス術後隣接椎間障害による胸髄症を呈した1例 Reviewed

    早川 景子, 松村 昭, 寺井 秀富

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会学術集会 抄録集   109 ( 0 )   173 - 173   2008

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    DOI: 10.11359/cjaost.109.0.173.0

    CiNii Article

  • 脊椎カリエス術後隣接椎間障害による胸髄症を呈した1例 Reviewed

    早川 景子, 松村 昭, 寺井 秀富

    中部日本整形外科災害外科学会学術集会 抄録集   109 ( 0 )   173 - 173   2008

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    DOI: 10.11359/cjaost.109.0.173.0

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  • 腰椎変性側弯症に対する顕微鏡視下片側進入両側除圧術の治療成績 Reviewed

    松村 昭, 並川 崇, 寺井 秀富

    中部日本整形外科災害外科学会学術集会 抄録集   109 ( 0 )   5 - 5   2008

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    DOI: 10.11359/cjaost.109.0.5.0

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  • 脊椎・末梢神経の成長・発達

    寺井 秀富

    バイオメカニズム学会誌   32 ( 2 )   65 - 68   2008( ISSN:02850885

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    体を動かすということは,筋を収縮させて体の関節を動かすということに他ならない.そのためには中枢神経で生じた命令が電気的信号として末梢神経を経て筋に達し,最終的に筋の収縮が起こるという一連のメカニズムが働いている.これら運動神経-筋の関係は胎生期に形成され,その関係を保ったまま成長し終生変わることがない.そのため,末梢神経-筋の情報伝達メカニズムを理解するためには胎生期での神経,筋の発生に関する知識が必要となる.本稿では,末梢神経,筋の発生と神経の構造についての解説を加え,2次ニューロンレベルでの神経支配メカニズムの形成に着目して解説する.

    DOI: 10.3951/sobim.32.65

    CiNii Article

  • 骨粗鬆症性椎骨骨折後の偽関節に関する予測因子 前向き多施設共同研究(Factors predictive of pseudoarthrosis following osteoporotic vertebral fracture: A prospective multicenter study) Reviewed

    Nakamura Hiroaki, Terai Hidetomi, Tsujio Tadao, Hoshino Masatoshi, Matsumura Akira, Namikawa Takashi, Suzuki Akinobu, Takayama Kazushi, Takaoka Kunoio

    日本脊椎脊髄病学会雑誌   18 ( 3 )   620 - 623   2007.12( ISSN:1346-4876

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    骨粗鬆症による椎骨骨折において、背部痛は通常骨が癒合するにつれ改善するが、骨折後に偽関節が生じると背部痛は遷延する。そこで、偽関節の発生率や、画像検査上における偽関節関連の予後因子について検討するため、骨粗鬆症性椎骨骨折患者について前向き多施設共同研究を行った。25施設から145名の患者(平均年齢76.2歳)を登録し、6ヵ月間追跡した。登録時と6ヵ月後に、単純X線とMRIの検査を行った。6ヵ月後、14%の患者で癒合がみられなかった。非癒合の予測因子として、胸腰移行部の骨折、後壁の損傷、T2強調画像における局所的な高信号変化や全体的な低信号変化が挙げられた。

  • Enhancing effects of a prostaglandin EP4 receptor agonist on recombinant human bone morphogenetic protein-2 mediated spine fusion in a rabbit model. Reviewed

    Namikawa T, Terai H, Hoshino M, Kato M, Toyoda H, Yano K, Nakamura H, Takaoka K

    Spine   32 ( 21 )   2294 - 9   2007.10( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e318154c5b6

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  • Enhancing effects of a prostaglandin EP4 receptor agonist on recombinant human bone morphogenetic protein-2 mediated spine fusion in a rabbit model Reviewed

    Namikawa Takashi, Terai Hidetomi, Hoshino Masatoshi, Kato Minori, Toyoda Hiromitsu, Yano Koichi, Nakamura Hiroaki, Takaoka Kunio

    SPINE   32 ( 21 )   2294 - 2299   2007.10( ISSN:0362-2436

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  • Enhancing effects of a prostaglandin EP4 receptor agonist on recombinant human bone morphogenetic protein-2 mediated spine fusion in a rabbit model. Reviewed

    Namikawa T, Terai H, Hoshino M, Kato M, Toyoda H, Yano K, Nakamura H, Takaoka K

    Spine   32 ( 21 )   2294 - 9   2007.10( ISSN:0362-2436

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    DOI: 10.1097/BRS.0b013e318154c5b6

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  • Prognostic factor on MRI findings inducing prolonged intractable pain due to pseudoarthrosis following osteoporotic vertebral fracture Reviewed

    Tsujio T., Nakamura H., Terai H., Matsumura A., Hoshino M., Suzuki A., Takayama K., Takaoka K.

    JOURNAL OF BONE AND MINERAL RESEARCH   22   S433 - S433   2007.09( ISSN:0884-0431

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  • Repair of bone defects in revision hip arthroplasty by implantation of a new bone-inducing material comprised of recombinant human BMP-2, Beta-TCP powder, and a biodegradable polymer: an experimental study in dogs. Reviewed

    Hoshino M, Namikawa T, Kato M, Terai H, Taguchi S, Takaoka K

    Journal of orthopaedic research : official publication of the Orthopaedic Research Society   25 ( 8 )   1042 - 51   2007.08( ISSN:0736-0266

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    DOI: 10.1002/jor.20424

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  • Repair of bone defects in revision hip arthroplasty by implantation of a new bone-inducing material comprised of recombinant human BMP-2, Beta-TCP powder, and a biodegradable polymer: an experimental study in dogs. Reviewed

    Hoshino M, Namikawa T, Kato M, Terai H, Taguchi S, Takaoka K

    Journal of orthopaedic research : official publication of the Orthopaedic Research Society   25 ( 8 )   1042 - 51   2007.08( ISSN:0736-0266

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    DOI: 10.1002/jor.20424

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  • 分子レベルからみた整形外科疾患 骨誘導能を有するrhBMP-2含有ペーストマテリアル Reviewed

    加藤 相勲, 中村 博亮, 並川 崇, 星野 雅俊, 寺井 秀富, 高岡 邦夫

    整形・災害外科   50 ( 8 )   834 - 835   2007.07( ISSN:0387-4095

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  • Regenerative repair of long intercalated rib defects using porous cylinders of beta-tricalcium phosphate: An experimental study in a canine model Reviewed

    Hoshino Masatoshi, Egi Takeshi, Terai Hidetomi, Namikawa Takashi, Takaoka Kunio

    PLASTIC AND RECONSTRUCTIVE SURGERY   119 ( 5 )   1431 - 1439   2007.04( ISSN:0032-1052

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    DOI: 10.1097/01.prs.0000256319.89619.c8

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  • Regenerative repair of long intercalated rib defects using porous cylinders of beta-tricalcium phosphate: an experimental study in a canine model. Reviewed

    Hoshino M, Egi T, Terai H, Namikawa T, Takaoka K

    Plastic and reconstructive surgery   119 ( 5 )   1431 - 1439   2007.04( ISSN:0032-1052

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    DOI: 10.1097/01.prs.0000256319.89619.c8

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  • 整形外科office-based surgery-1人でできるテクニック 脊椎 神経根性疼痛に対するブロック療法 Reviewed

    寺井 秀富, 高岡 邦夫

    別冊整形外科   1 ( 51 )   7 - 12   2007.04( ISSN:02871645

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    DOI: 10.15106/j04037.2007181318

  • A fusion protein of hepatocyte growth factor for immobilization to collagen. Reviewed

    Kitajima T, Terai H, Ito Y

    Biomaterials   28 ( 11 )   1989 - 97   2007.04( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2006.12.022

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  • 【整形外科office-based surgery-1人でできるテクニック】脊椎 神経根性疼痛に対するブロック療法 Reviewed

    寺井 秀富, 高岡 邦夫

    別冊整形外科   ( 51 )   7 - 12   2007.04( ISSN:0287-1645

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  • 【関節リウマチおよびその脊髄病変】骨粗鬆症性脊椎椎体骨折による遅発性脊髄麻痺に対する手術療法 Reviewed

    辻尾 唯雄, 中村 博亮, 寺井 秀富, 松村 昭, 星野 雅俊, 高岡 邦夫

    脳21   10 ( 2 )   178 - 183   2007.04( ISSN:1344-0128

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    骨粗鬆症性椎体骨折の治療として一般的に、保存療法が行われ、多くの症例では骨癒合とともに疼痛は軽快することが多い。しかし、一方では高度な椎体圧潰や椎体偽関節を生じ、さらには遅発性に神経症状を発症するものがある。それらに対する手術術式として、脊柱再建と前方除圧が短椎間固定で行える前方除圧固定が最も理にかなっている。しかし、本症の対象患者は高齢者で多発骨折例も多いためにその適応を狭めている。我々は、腰背部痛を主症状とし下肢神経症状が軽微なものには椎体形成術のみ行い、下肢神経症状が高度なものには椎体形成術と後方除圧固定術の併用を行っている。一方椎体骨折が高度に圧潰したまま癒合し局所後彎による神経要素の圧排が強い場合には、脊椎後方短縮術を行っている。治療対象となる症例は内科的合併症を有することが多く、骨脆弱性をも有するため手術適応の決定とその方法の選択には慎重でなければならない。(著者抄録)

  • Engineering of implantable cartilaginous structures from bone marrow-derived mesenchymal stem cells. Reviewed

    Hannouche D, Terai H, Fuchs JR, Terada S, Zand S, Nasseri BA, Petite H, Sedel L, Vacanti JP

    Tissue engineering   13 ( 1 )   87 - 99   2007.01( ISSN:1076-3279

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    DOI: 10.1089/ten.2006.0067

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  • 【骨粗鬆性脊椎骨折の発症リスクファクターと予後因子】早期MRIからみた骨粗鬆症性脊椎椎体骨折の予後不良因子 Reviewed

    辻尾 唯雄, 中村 博亮, 星野 雅俊, 寺井 秀富, 松村 昭, 並川 崇, 鈴木 亨暢, 高山 和士, 高岡 邦夫

    骨・関節・靱帯   20 ( 1 )   45 - 53   2007.01( ISSN:0915-1125

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    椎体骨折後の予後不良因子、特に偽関節へ移行する危険因子を特定するため、受傷後早期のMRI画像について検討した。新鮮骨粗鬆症性椎体骨折で、受傷後より1週以内にMRIを実施でき、6ヵ月以上その後の経過を観察することができた58例62椎体を対象とした。T1強調像で低輝度性変化が広範囲にみられ、T2強調像でも広範囲に低輝度を呈する場合やまたはT2強調像では限局した高輝度を呈する場合は偽関節へ移行する因子として高いオッズ比を示し、偽関節発生を予見するうえで有用であった。

  • 生体分解性polymer(PLA-DX-PEG)とrhBMP-2の至適配合 Reviewed

    加藤 相勲, 寺井 秀富, 並川 崇, 星野 雅俊, 高岡 邦夫

    Orthopaedic Ceramic Implants   25   19 - 22   2006.12( ISSN:0289-2855

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    骨形成蛋白(BMP)の担体としての有効性について生体分解性polymer(ポリ乳酸-パラジオキサノンポリエチレングリコール共重合体)と牛由来I型collagen(collagen)で比較した。また、少量のBMPでより多量の骨形成を得るためのpolymerとBMPの至適配合を決定することを目的に、polymerとBMPと骨形成量との関係を調査した。生体分解性polymerはI型collagenよりもBMPの担体として有効であった。polymerをBMPの担体として用いた時の骨形成量は、BMP含有量、polymerの体積量に伴い増加した。マウス背筋筋膜下異所性骨モデルにおける、polymerのrhBMP-2至適含有濃度は0.003wt%であった。

  • Accelerated repair of a bone defect with a synthetic biodegradable bone-inducing implant Reviewed

    80 ( 11 )   2006.11( ISSN:00215325

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  • Accelerated repair of a bone defect with a synthetic biodegradable bone-inducing implant Reviewed

    80 ( 11 )   899   2006.11( ISSN:00215325

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  • Endoscopic vertebroplasty for the treatment of chronic vertebral compression fracture. Technical note. Reviewed

    Hoshino M, Nakamura H, Konishi S, Nagayama R, Terai H, Tsujio T, Namikawa T, Kato M, Takaoka K

    Journal of neurosurgery. Spine   5 ( 5 )   461 - 7   2006.11( ISSN:1547-5654

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    DOI: 10.3171/spi.2006.5.5.461

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  • Endoscopic vertebroplasty for the treatment of chronic vertebral compression fracture - Technical note Reviewed

    Hoshino Masatoshi, Nakamura Hiroaki, Konishi Sadahiko, Nagayama Ryuichi, Terai Hidetomi, Tsujio Tadao, Namikawa Takashi, Kato Minori, Takaoka Kunio

    JOURNAL OF NEUROSURGERY-SPINE   5 ( 5 )   461 - 467   2006.11( ISSN:1547-5654

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  • Endoscopic vertebroplasty for the treatment of chronic vertebral compression fracture. Technical note. Reviewed

    Hoshino M, Nakamura H, Konishi S, Nagayama R, Terai H, Tsujio T, Namikawa T, Kato M, Takaoka K

    Journal of neurosurgery. Spine   5 ( 5 )   461 - 7   2006.11( ISSN:1547-5654

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    DOI: 10.3171/spi.2006.5.5.461

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  • Accelerated repair of a bone defect with a synthetic biodegradable bone-inducing implant Reviewed

    MATSUSHITA NAOFUMI, TERAI HIDETOMI, OKADA TAKAO, NOZAKI KAZUTOSHI, INOUE HIKARU, MIYAMOTO SHIMPEI, TAKAOKA KUNIO

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   11 ( 5 )   505 - 511   2006.10( ISSN:09492658

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  • Accelerated repair of a bone defect with a synthetic biodegradable bone-inducing implant Reviewed

    MATSUSHITA NAOFUMI, TERAI HIDETOMI, OKADA TAKAO, NOZAKI KAZUTOSHI, INOUE HIKARU, MIYAMOTO SHIMPEI, TAKAOKA KUNIO

    J Orthop Sci   11 ( 5 )   505 - 511   2006.10( ISSN:09492658

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  • Repair of long intercalated rib defects using porous beta-tricalcium phosphate cylinders containing recombinant human bone morphogenetic protein-2 in dogs Reviewed

    Hoshino Masatoshi, Egi Takeshi, Terai Hidetomi, Namikawa Takashi, Takaoka Kunio

    BIOMATERIALS   27 ( 28 )   4934 - 4940   2006.10( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2006.04.044

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  • Accelerated repair of a bone defect with a synthetic biodegradable bone-inducing implant. Reviewed

    Matsushita N, Terai H, Okada T, Nozaki K, Inoue H, Miyamoto S, Takaoka K

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association   11 ( 5 )   505 - 11   2006.10( ISSN:0949-2658

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    DOI: 10.1007/s00776-006-1048-3

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  • Repair of long intercalated rib defects using porous beta-tricalcium phosphate cylinders containing recombinant human bone morphogenetic protein-2 in dogs. Reviewed

    Hoshino M, Egi T, Terai H, Namikawa T, Takaoka K

    Biomaterials   27 ( 28 )   4934 - 40   2006.10( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2006.04.044

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  • 合成生物分解性骨誘導インプラントによる骨欠損の修復促進(Accelerated repair of a bone defect with a synthetic biodegradable bone-inducing implant) Reviewed

    Matsushita Naofumi, Terai Hidetomi, Okada Takao, Nozaki Kazutoshi, Inoue Hikaru, Miyamoto Shimpei, Takaoka Kunio

    Journal of Orthopaedic Science   11 ( 5 )   505 - 511   2006.10( ISSN:0949-2658

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    p-ジオキサノン及びポリエチレングリコールを挿入したポリ-D,L-乳酸ブロックコポリマー、多孔質β燐酸三カルシウム(βTCP)顆粒及びBMPからインプラントを作成し、ウサギ大腿骨の皮質骨欠損部に充填した。インプラントのBMP含量により骨修復に差がみられた。三次元CT及び病理組織学的に観察される皮質骨及び海綿骨の修復は高濃度BMPを含むインプラント(BMP-H)で顕著であり、低濃度BMP含有(BMP-L)及びBMP不含有(対照)のインプラントでは僅かに修復されたのみであった。BMP-HではβTCPの殆どが充填後6週までに吸収されたが、BMP-L及び対照では残存していた。BMP保持合成ポリマーで被覆したβTCP顆粒は海綿骨及び皮質骨の欠損の修復促進に有効である。

  • Vertebroplasty for pseudoarthrosis following osteoporotic vertebral fracture : Use of urinary balloon catheter and endoscope Reviewed

    HOSHINO Masatoshi

    49 ( 5 )   959 - 960   2006.09( ISSN:00089443

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  • Vertebroplasty for pseudoarthrosis following osteoporotic vertebral fracture : Use of urinary balloon catheter and endoscope Reviewed

    HOSHINO Masatoshi

    49 ( 5 )   959 - 960   2006.09( ISSN:00089443

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  • Accelerated repair of a bone defect with a synthetic biodegradable bone-inducing implant Reviewed

    Matsushita Naofumi, Terai Hidetomi, Okada Takao, Nozaki Kazutoshi, Inoue Hikaru, Miyamoto Shimpei, Takaoka Kunio

    JOURNAL OF ORTHOPAEDIC SCIENCE   11 ( 5 )   505 - 511   2006.09( ISSN:0949-2658

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    DOI: 10.1007/s00776-006-1048-3

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  • 骨粗鬆症性椎体骨折後偽関節例に対するCPCを用いた椎体形成術 バルーンと内視鏡の応用 Reviewed

    星野 雅俊, 中村 博亮, 小西 定彦, 寺井 秀富, 辻尾 唯雄, 高岡 邦夫

    中部日本整形外科災害外科学会雑誌   49 ( 5 )   959 - 960   2006.09( ISSN:0008-9443

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    当科では骨粗鬆症性椎体骨折後偽関節に対して、椎体内壊死組織の掻爬と充分なCPC(calcium phosphate cement)挿入腔の形成を目的に、ウロマチックバルーンと内視鏡を用いた椎体形成術を行っている。本術式の適応と手術方法を紹介し、治療成績を報告した。適応は「明らかな麻痺がなく、遷延する強い腰背部痛のためADLが高度に制限されている症例」としている。2003年3月〜2006年1月に手術を行い術後1年以上経過観察しえた14例の成績は、疼痛のvisual analogue scaleが術前平均85から術後19に改善した。ADLは術前10例が歩行不能、4例が介助歩行であったが、術後は6例が独歩可能、8例が介助歩行可能となった。X線学的評価では、%椎体高は術前平均38%、術中85%、術後1ヵ月61%、術後1年61%で、矯正損失を術後1ヵ月まで認めたが、その後変形は進行せず安定化した。

  • Ectopic bone formation in mice associated with a lactic acid/dioxanone/ethylene glycol copolymer-tricalcium phosphate composite with added recombinant human bone morphogenetic protein-2. Reviewed

    Kato M, Namikawa T, Terai H, Hoshino M, Miyamoto S, Takaoka K

    Biomaterials   27 ( 21 )   3927 - 33   2006.07( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2006.03.013

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  • Ectopic bone formation in mice associated with a lactic acid/dioxanone/ethylene glycol copolymer-tricalcium phosphate composite with added recombinant human bone morphogenetic protein-2. Reviewed

    Kato M, Namikawa T, Terai H, Hoshino M, Miyamoto S, Takaoka K

    Biomaterials   27 ( 21 )   3927 - 33   2006.07( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2006.03.013

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  • [Application of bone morphogenetic protein (BMP) in regenerative medicine of bone]. Reviewed

    Terai H, Takaoka K

    Clinical calcium   16 ( 5 )   745 - 51   2006.05( ISSN:0917-5857

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    DOI: CliCa0605745751

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  • Objective assessment of reduced invasiveness in MED Reviewed

    Sasaoka R, Nakamura H, Konishi S, Nagayama R, Suzuki E, Terai H, Takaoka K

    EUROPEAN SPINE JOURNAL   15 ( 5 )   577 - 582   2006.05( ISSN:0940-6719

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    DOI: 10.1007/s00586-005-0912-8

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  • [Experimental spinal fusion in a rabbit model with new drug delivery system for BMP]. Reviewed

    Namikawa T, Terai H, Takaoka K

    Clinical calcium   16 ( 5 )   793 - 800   2006.05( ISSN:0917-5857

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    DOI: CliCa0605793800

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  • Cheilitis as a variation of Candida-associated lesions. Reviewed

    Terai H, Shimahara M

    Oral diseases   12 ( 3 )   349 - 52   2006.05( ISSN:1354-523X

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    DOI: 10.1111/j.1601-0825.2005.01212.x

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  • Objective assessment of reduced invasiveness in MED. Compared with conventional one-level laminotomy. Reviewed

    Sasaoka R, Nakamura H, Konishi S, Nagayama R, Suzuki E, Terai H, Takaoka K

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society   15 ( 5 )   577 - 82   2006.05( ISSN:0940-6719

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    DOI: 10.1007/s00586-005-0912-8

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  • [Application of bone morphogenetic protein (BMP) in regenerative medicine of bone]. Reviewed

    Terai H, Takaoka K

    Clinical calcium   16 ( 5 )   745 - 51   2006.05( ISSN:0917-5857

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    PubMed

  • [Experimental spinal fusion in a rabbit model with new drug delivery system for BMP]. Reviewed

    Namikawa T, Terai H, Takaoka K

    Clinical calcium   16 ( 5 )   793 - 800   2006.05( ISSN:0917-5857

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    PubMed

  • Evaluation of Prognostic Factors for Osteoporotic Vertebral Fractures Reviewed

    41 ( 4 )   499 - 506   2006.04( ISSN:05570433 ( eISSN:18821286

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    DOI: 10.11477/mf.1408100305

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  • 【BMPの基礎と臨床】BMPの新しいDDSによる実験的脊椎固定手術 Reviewed

    並川 崇, 寺井 秀富, 高岡 邦夫

    Clinical Calcium   16 ( 5 )   793 - 800   2006.04( ISSN:0917-5857

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    脊柱不安定性を有する変性性脊椎疾患に対し,脊椎安定性再建のために外科的に脊椎固定を行うことが多い.通常,脊椎固定は正常部位(主に腸骨)から採取した自家骨を移植し,椎間を骨性に癒合する方法(脊椎固定術)が選択される.この方法の問題点として,採骨部の疼痛,変形,瘢痕形成などの合併症がしばしば問題となる.これを回避すべく,骨形成タンパク(BMP)を使用した骨癒合が注目され,その使用により良好な臨床成績が報告されている.しかし,現時点ではこの方法にも問題がある.コストが高いこと,BMPのデリバリーシステム(drug delivery system:DDS)ウシ由来コラーゲンスポンジを用いていること,力学的強度に乏しいこと,プリオン病媒介の潜在的危惧,などである.これらの問題解決のために我々は新しいポリマーであるポリ乳酸-ポリエチレングリコール(PLA-PEG)を開発し,これにさらにβ-リン酸三カルシウム(β-TCP),BMP-2を複合して骨誘導活性を有する人工材料を開発した.これを用いてウサギモデルで後側方脊椎固定を行うことに成功した(著者抄録)

  • 【脊椎脊髄病学 最近の進歩 2006】骨粗鬆症性脊椎椎体骨折における予後不良因子の検討 Reviewed

    辻尾 唯雄, 中村 博亮, 星野 雅俊, 寺井 秀富, 高岡 邦夫

    臨床整形外科   41 ( 4 )   499 - 506   2006.04( ISSN:0557-0433

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    骨粗鬆症性脊椎椎体骨折における予後不良因子について検討した.対象は,骨粗鬆症に伴う新鮮椎体骨折44例50椎体(男性12例,女性32例・平均年齢73.3歳)で,受傷後6ヵ月時点での骨癒合群(34例38椎体)と偽関節群(11例12椎体)に分けて比較した.骨癒合群と偽関節群の受傷時平均年齢は72.9歳,76.2歳,70歳以上の割合は65%,82%,受傷原因が明白なのは73.5%,27.3%であった.椎体骨折部位はL1で22例と最も多く,Th11〜L2の胸腰椎移行部で37例(74%)を占めた.偽関節群12椎体中11椎体が胸腰椎移行部で,特にTh12では70%(7/10)を占めた.初診時の平均前方椎体圧潰率は骨癒合群19.0%,偽関節群17.4%で差はなかったが,最終時では34.1%,50.6%と有意差を認めた.椎体の後壁損傷がない39椎体中5椎体(12.8%)が,損傷のあった11椎体中7椎体(63.6%)が偽関節に移行した.MRIでは,低輝度変化が広範に見られるT1強調像のtotal typeで45.8%に,T2強調像のLW typeで61.5%に偽関節を認めた

  • 【BMPの基礎と臨床】BMPの骨再生医学への応用 Reviewed

    寺井 秀富, 高岡 邦夫

    Clinical Calcium   16 ( 5 )   745 - 751   2006.04( ISSN:0917-5857

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    臨床領域でのbone morphogenetic protein(BMP)研究の主たる目的は,BMPが持つ骨誘導能を利用して効果的能率的に骨再生修復する新技術を開発することである.そのための具体的課題として,有効なBMPの担体の開発,BMPの骨形成作用の促進と効率化の技術の開発があげられる.これらの新技術が開発されれば,現在広く行われている自家骨移植に代わる有効な骨形成促進技術となり,さらに,骨折治癒の促進,偽関節の治療,脊椎固定,腫瘍切除後の骨欠損再建,人工関節再置換での骨欠損補填,骨形成活性を備えた人工材料の開発等,整形外科領域での幅広い応用と臨床応用の普及が期待できる(著者抄録)

  • The Efficacy of Local Administration of Prostaglandin E EP-4 Receptor Agonist with rhBMP-2 for Enhancing Bone Formation in a Rabbit Spinal Fusion Model Reviewed

    NAMIKAWA T.

    17 ( 1 )   2006.03( ISSN:13464876

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  • The Efficacy of Local Administration of Prostaglandin E EP-4 Receptor Agonist with rhBMP-2 for Enhancing Bone Formation in a Rabbit Spinal Fusion Model Reviewed

    NAMIKAWA T.

    17 ( 1 )   150   2006.03( ISSN:13464876

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  • A biodegradable delivery system for antibiotics and recombinant human bone morphogenetic protein-2: A potential treatment for infected bone defects Reviewed

    Suzuki A, Terai H, Toyoda H, Namikawa T, Yokota Y, Tsunoda T, Takaoka K

    JOURNAL OF ORTHOPAEDIC RESEARCH   24 ( 3 )   327 - 332   2006.03( ISSN:0736-0266

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    DOI: 10.1002/jor.20049

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  • Optimized use of a biodegradable polymer as a carrier material for the local delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2) Reviewed

    Kato M, Toyoda H, Namikawa T, Hoshino M, Terai H, Miyamoto S, Takaoka K

    BIOMATERIALS   27 ( 9 )   2035 - 2041   2006.03( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2005.10.007

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  • A biodegradable delivery system for antibiotics and recombinant human bone morphogenetic protein-2: A potential treatment for infected bone defects. Reviewed

    Suzuki A, Terai H, Toyoda H, Namikawa T, Yokota Y, Tsunoda T, Takaoka K

    Journal of orthopaedic research : official publication of the Orthopaedic Research Society   24 ( 3 )   327 - 32   2006.03( ISSN:0736-0266

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    DOI: 10.1002/jor.20049

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  • Optimized use of a biodegradable polymer as a carrier material for the local delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2). Reviewed

    Kato M, Toyoda H, Namikawa T, Hoshino M, Terai H, Miyamoto S, Takaoka K

    Biomaterials   27 ( 9 )   2035 - 41   2006.03( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2005.10.007

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  • 後腹膜鏡下腰椎前方固定術の実際 Reviewed

    中村 博亮, 小西 定彦, 長山 隆一, 寺井 秀富, 辻尾 唯雄, 高岡 邦夫

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会学術集会 抄録集   106 ( 0 )   61 - 61   2006

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    DOI: 10.11359/cjaost.106.0.61.0

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  • 骨粗鬆症性椎体骨折後偽関節例に対するCPCを用いた椎体形成術 ―バルーンと内視鏡の応用― Reviewed

    星野 雅俊, 中村 博亮, 小西 定彦, 長山 隆一, 寺井 秀富, 辻尾 唯雄, 高岡 邦夫

    中部日本整形外科災害外科学会 中部日本整形外科災害外科学会学術集会 抄録集   106 ( 0 )   278 - 278   2006

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    DOI: 10.11359/cjaost.106.0.278.0

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  • Vertebroplasty for pseudoarthrosis following osteoporotic vertebral fracture Reviewed

    HOSHINO Masatoshi

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   49 ( 5 )   959 - 960   2006

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    DOI: 10.11359/chubu.2006.959

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  • 後腹膜鏡下腰椎前方固定術の実際 Reviewed

    中村 博亮, 小西 定彦, 長山 隆一, 寺井 秀富, 辻尾 唯雄, 高岡 邦夫

    中部日本整形外科災害外科学会学術集会 抄録集   106 ( 0 )   61 - 61   2006

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    DOI: 10.11359/cjaost.106.0.61.0

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  • 骨粗鬆症性椎体骨折後偽関節例に対するCPCを用いた椎体形成術 ―バルーンと内視鏡の応用― Reviewed

    星野 雅俊, 中村 博亮, 小西 定彦, 長山 隆一, 寺井 秀富, 辻尾 唯雄, 高岡 邦夫

    中部日本整形外科災害外科学会学術集会 抄録集   106 ( 0 )   278 - 278   2006

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    DOI: 10.11359/cjaost.106.0.278.0

    CiNii Article

  • Vertebroplasty for pseudoarthrosis following osteoporotic vertebral fracture Reviewed

    HOSHINO Masatoshi

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   49 ( 5 )   959 - 960   2006( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2006.959

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  • rhBMP-2/PLA-DX-PEG/β-TCP compositeを使用した家兎腰椎後側方固定術での脊椎固定率に関する研究 Reviewed

    並川 崇, 寺井 秀富, 鈴木 英介, 星野 雅俊, 中村 博亮, 高岡 邦夫

    Orthopaedic Ceramic Implants   23〜24   105 - 109   2005.12( ISSN:0289-2855

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    高分子量ポリ(乳酸-ジオキサノン)-ポリエチレングリコールブロック共重合体(PLA-DX-PEG)を開発した.PLA-DX-PEGをヒトリコンビナント骨形成蛋白(rhBMP)-2の薬物伝達系に用い,これに生体親和性,吸収性,骨伝導性に優れたβ-リン酸三カルシウム(β-TCP)を配合して新たな骨形成性人工骨を開発した.ウサギ腰椎後側方固定モデルに使用し,PLA-DX-PEG/β-TCPのBMP担体としての有用性を評価した.rhBMP-2/PLA-DX-PEG/β-TCPの使用により6週で100%の固定率を得るrhBMP-2の所要量は片側につき15および30μgで,過去の報告と比し,顕著に少なかった.この骨形成性人工骨の,自家骨,従来の人工代替移植材料,および同種骨移植に替わる新しい材料となる可能性が示唆された

  • Augmentation of bone morphogenetic protein-induced bone mass by local delivery of a prostaglandin E EP4 receptor agonist Reviewed

    Toyoda H, Terai H, Sasaoka R, Oda K, Takaoka K

    BONE   37 ( 4 )   555 - 562   2005.10( ISSN:8756-3282

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    DOI: 10.1016/j.bone.2005.04.042

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  • Hepatocyte growth factor contributes to fracture repair by upregulating the expression of BMP receptors Reviewed

    Imai Y, Terai H, Nomura-Furuwatari C, Mizuno S, Matsumoto K, Nakamura T, Takaoka K

    JOURNAL OF BONE AND MINERAL RESEARCH   20 ( 10 )   1723 - 1730   2005.10( ISSN:0884-0431

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    DOI: 10.1359/JBMR.050607

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  • Augmentation of bone morphogenetic protein-induced bone mass by local delivery of a prostaglandin E EP4 receptor agonist. Reviewed

    Toyoda H, Terai H, Sasaoka R, Oda K, Takaoka K

    Bone   37 ( 4 )   555 - 62   2005.10( ISSN:8756-3282

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    DOI: 10.1016/j.bone.2005.04.042

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  • Hepatocyte growth factor contributes to fracture repair by upregulating the expression of BMP receptors. Reviewed

    Imai Y, Terai H, Nomura-Furuwatari C, Mizuno S, Matsumoto K, Nakamura T, Takaoka K

    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research   20 ( 10 )   1723 - 30   2005.10( ISSN:0884-0431

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    DOI: 10.1359/JBMR.050607

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  • Surgical treatment for ischemic mitral regurgitation: strategy for a tethered valve. Reviewed

    Terai H, Tao K, Sakata R

    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia   11 ( 5 )   288 - 92   2005.10( ISSN:1341-1098

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  • Changes in cardiac tissue characterization in carriers with gene mutations associated with hypertrophic cardiomyopathy. Reviewed

    Kaneda T, Shimizu M, Ino H, Yamaguchi M, Terai H, Fujino N, Nagata M, Sakata K, Mabuchi H

    International journal of cardiology   104 ( 2 )   170 - 5   2005.09( ISSN:0167-5273

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    DOI: 10.1016/j.ijcard.2004.11.009

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  • Culture of human umbilical vein endothelial cells on immobilized vascular endothelial growth factor. Reviewed

    Ito Y, Hasuda H, Terai H, Kitajima T

    Journal of biomedical materials research. Part A   74 ( 4 )   659 - 65   2005.09( ISSN:1549-3296

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    DOI: 10.1002/jbm.a.30360

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  • 卒後研修講座 骨再生医療と骨形成蛋白(BMP) Reviewed

    寺井 秀富, 高岡 邦夫

    整形外科   56 ( 10 )   1361 - 1366   2005.09( ISSN:00305901 ( eISSN:24329444

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    DOI: 10.15106/j00764.2005266988

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  • Repair of an intercalated long bone defect with a synthetic biodegradable bone-inducing implant Reviewed

    Yoneda M, Terai H, Imai Y, Okada T, Nozaki K, Inoue H, Miyamoto S, Takaoka K

    BIOMATERIALS   26 ( 25 )   5145 - 5152   2005.09( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2005.01.054

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  • Repair of an intercalated long bone defect with a synthetic biodegradable bone-inducing implant. Reviewed

    Yoneda M, Terai H, Imai Y, Okada T, Nozaki K, Inoue H, Miyamoto S, Takaoka K

    Biomaterials   26 ( 25 )   5145 - 52   2005.09( ISSN:0142-9612

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    DOI: 10.1016/j.biomaterials.2005.01.054

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  • 卒後研修講座 骨再生医療と骨形成蛋白(BMP) Reviewed

    寺井 秀富, 高岡 邦夫

    整形外科   56 ( 10 )   1361 - 1366   2005.09( ISSN:0030-5901

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  • Experimental spinal fusion with recombinant human bone morphogenetic protein-2 delivered by a synthetic polymer and beta-tricalcium phosphate in a rabbit model. Reviewed

    Namikawa T, Terai H, Suzuki E, Hoshino M, Toyoda H, Nakamura H, Miyamoto S, Takahashi N, Ninomiya T, Takaoka K

    Spine   30 ( 15 )   1717 - 22   2005.08( ISSN:0362-2436

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  • Experimental spinal fusion with recombinant human bone morphogenetic protein-2 delivered by a synthetic polymer and beta-tricalcium phosphate in a rabbit model Reviewed

    Namikawa T, Terai H, Suzuki E, Hoshino M, Toyoda H, Nakamura H, Miyamoto S, Takahashi N, Ninomiya T, Takaoka K

    SPINE   30 ( 15 )   1717 - 1722   2005.08( ISSN:0362-2436

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  • Experimental Spinal Fusion With Recombinant Human Bone Morphogenetic Protein-2 Delivered by a Synthetic Polymer and β-Tricalcium Phosphate in a Rabbit Model Reviewed

    NAMIKAWA Takashi, TERAI Hidetomi, SUZUKI Eisuke, HOSHINO Masatoshi, TOYODA Hiromitsu, NAKAMURA Hiroaki, MIYAMOTO Shimpei, TAKAHASHI Naoyuki, NINOMIYA Tadashi, TAKAOKA Kunio

    Spine   30 ( 15 )   1717 - 1722   2005.08( ISSN:03622436

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  • Experimental spinal fusion with recombinant human bone morphogenetic protein-2 delivered by a synthetic polymer and beta-tricalcium phosphate in a rabbit model. Reviewed

    Namikawa T, Terai H, Suzuki E, Hoshino M, Toyoda H, Nakamura H, Miyamoto S, Takahashi N, Ninomiya T, Takaoka K

    Spine   30 ( 15 )   1717 - 22   2005.08( ISSN:0362-2436

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    DOI: 10.1097/01.brs.0000172155.17239.fa

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  • Experimental Spinal Fusion With Recombinant Human Bone Morphogenetic Protein-2 Delivered by a Synthetic Polymer and β-Tricalcium Phosphate in a Rabbit Model Reviewed

    NAMIKAWA Takashi, TERAI Hidetomi, SUZUKI Eisuke, HOSHINO Masatoshi, TOYODA Hiromitsu, NAKAMURA Hiroaki, MIYAMOTO Shimpei, TAKAHASHI Naoyuki, NINOMIYA Tadashi, TAKAOKA Kunio

    Spine   30 ( 15 )   1717 - 1722   2005.08( ISSN:03622436

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  • Atrophic tongue associated with Candida. Reviewed

    Terai H, Shimahara M

    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology   34 ( 7 )   397 - 400   2005.08( ISSN:0904-2512

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    DOI: 10.1111/j.1600-0714.2005.00324.x

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  • 【骨・軟骨移植 最近の知見】 骨移植 基礎研究 骨形成蛋白(BMP) 新しい骨形成蛋白(BMP)デリバリーシステムを利用した長管骨骨欠損の修復の試み Reviewed

    米田 昌弘, 寺井 秀富, 高岡 邦夫

    別冊整形外科   1 ( 47 )   26 - 30   2005.04( ISSN:02871645

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    DOI: 10.15106/j04037.2005148498

  • An experimental model of Stanford type B aortic dissection. Reviewed

    Terai H, Tamura N, Yuasa S, Nakamura T, Shimizu Y, Komeda M

    Journal of vascular and interventional radiology : JVIR   16 ( 4 )   515 - 9   2005.04( ISSN:1051-0443

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    DOI: 10.1097/01.RVI.0000151142.80319.85

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  • 【骨・軟骨移植 最近の知見】骨移植 基礎研究 骨形成蛋白(BMP) 新しい骨形成蛋白(BMP)デリバリーシステムを利用した長管骨骨欠損の修復の試み Reviewed

    米田 昌弘, 寺井 秀富, 高岡 邦夫

    別冊整形外科   ( 47 )   26 - 30   2005.04( ISSN:0287-1645

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  • A case report of central disc herniation at C3/4 presenting specific symptoms Reviewed

    CHO Hisanori

    48 ( 2 )   251 - 252   2005.03( ISSN:00089443

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  • 特異な神経徴候を示したC3/4間中心型椎間板ヘルニアの1例 Reviewed

    曹 寿憲, 寺井 秀富, 中村 博亮, 長山 隆一, 高岡 邦夫

    中部日本整形外科災害外科学会雑誌   48 ( 2 )   251 - 252   2005.03( ISSN:0008-9443

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    70歳男.両手掌のしびれが出現・増強し,更に急速な手指巧緻性低下,歩行時のふらつきを自覚するようになった.MRI矢状断像ではC3/4間での脊髄の圧迫が著明で,ミエログラムでは造影剤の途絶像がみられた.母指探し試験では,開眼時にはかろうじて母指の把握が可能であったが,閉眼時には把握不能であった.鼻指鼻試験では,患者の指先が検者の示指先端に到達する直前に動揺を認めた.C3/4頸椎正中型椎間板ヘルニアと診断し,C3/4一椎間の前方除圧固定術を行った.術後母指探し試験や鼻指鼻試験は改善し,これら症状はC3/4圧迫に特異的な徴候と考えられた.日常診療において両手足のしびれを初発症状とする場合,上位頸椎病変を想起すべきであると思われた

  • Compound heterozygosity for mutations Asp611--&gt;Tyr in KCNQ1 and Asp609--&gt;Gly in KCNH2 associated with severe long QT syndrome. Reviewed

    Yamaguchi M, Shimizu M, Ino H, Terai H, Hayashi K, Kaneda T, Mabuchi H, Sumita R, Oshima T, Hoshi N, Higashida H

    Clinical science (London, England : 1979)   108 ( 2 )   143 - 50   2005.02( ISSN:0143-5221

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    DOI: 10.1042/CS20040220

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  • Balloon kyphoplasty for pseudoarthrosis following osteoporotic compression fracture Reviewed

    HOSHINO Masatoshi

    48 ( 1 )   155 - 156   2005.01( ISSN:00089443

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  • Balloon kyphoplasty for pseudoarthrosis following osteoporotic compression fracture Reviewed

    HOSHINO Masatoshi

    48 ( 1 )   155 - 156   2005.01( ISSN:00089443

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  • Differentiation between patients with takotsubo cardiomyopathy and those with anterior acute myocardial infarction. Reviewed

    Inoue M, Shimizu M, Ino H, Yamaguchi M, Terai H, Fujino N, Sakata K, Funada A, Tatami R, Ishise S, Kanaya H, Mabuchi H

    Circulation journal : official journal of the Japanese Circulation Society   69 ( 1 )   89 - 94   2005.01( ISSN:1346-9843

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    DOI: 10.1253/circj.69.89

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  • 骨粗鬆症性椎体骨折偽関節例に対するballoon kyphoplasty Reviewed

    星野 雅俊, 中村 博亮, 長山 隆一, 寺井 秀富, 高岡 邦夫

    中部日本整形外科災害外科学会雑誌   48 ( 1 )   155 - 156   2005.01( ISSN:0008-9443

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    骨粗鬆症性椎体骨折偽関節症例8例9椎体(男性3例・女性5例,平均年齢72歳)を対象にリン酸カルシウム骨ペースト(CPC)挿入腔の形成と可及的後彎の矯正目的にウロマチックバルーンを応用した低侵襲のKyphoplastyを試みた.対象の罹患椎はTh12;6椎体・L1・L2・L4各1椎体で,受傷から手術までの経過観察期間は平均5.7ヵ月であった.手術時間は平均177分(135〜212分)・出血量平均87ml(10〜250ml)で,全身合併症は全例で認めず,術前寝たきり6例・車椅子移動1例・歩行器歩行1例であったが,術後は全例歩行可能となった.%椎体高の平均は前壁で術前49%・術直後88%・最終観察時71%であり,後壁で術前82%・術直後90%・最終観察時82%であった.局所後彎角は術前17°,術直後4°,最終観察時10°であった.以上より,短期成績ではあるが本法は骨粗鬆症性椎体骨折偽関節症例に対して有用な方法と考えられた.本法の実際について解説した

  • Balloon kyphoplasty for pseudoarthrosis following osteoporotic compression fracture Reviewed

    HOSHINO Masatoshi

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   48 ( 1 )   155 - 156   2005( ISSN:0008-9443

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    DOI: 10.11359/chubu.2005.155

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  • A case report of central disc herniation at C3/4 presenting specific symptoms Reviewed

    CHO Hisanori

    THE CENTRAL JAPAN ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY, The Central Japan Journal of Orthopaedic Surgery & Traumatology   48 ( 2 )   251 - 252   2005( ISSN:0008-9443

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    DOI: 10.11359/chubu.2005.251

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  • Balloon kyphoplasty for pseudoarthrosis following osteoporotic compression fracture Reviewed

    HOSHINO Masatoshi

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   48 ( 1 )   155 - 156   2005( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2005.155

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  • A case report of central disc herniation at C3/4 presenting specific symptoms Reviewed

    CHO Hisanori

    The Central Japan Journal of Orthopaedic Surgery & Traumatology   48 ( 2 )   251 - 252   2005( ISSN:00089443 ( eISSN:13490885

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    DOI: 10.11359/chubu.2005.251

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  • Anterior interbody fusion utilizing endoscope with retroperitoneal approach for lumbar degenerative spondylolisthesis Reviewed

    9 ( 6 )   655 - 660   2004.12( ISSN:13446703 ( eISSN:21866643

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    DOI: 10.11477/mf.4426900556

  • Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane). Reviewed

    Shin M, Matsuda K, Ishii O, Terai H, Kaazempur-Mofrad M, Borenstein J, Detmar M, Vacanti JP

    Biomedical microdevices   6 ( 4 )   269 - 78   2004.12( ISSN:1387-2176

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    DOI: 10.1023/B:BMMD.0000048559.29932.27

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  • 【内視鏡下脊椎手術の進歩】腰椎変性すべり症に対する後腹膜鏡視下前方固定術 Reviewed

    中村 博亮, 長山 隆一, 寺井 秀富, 高岡 邦夫

    日本内視鏡外科学会雑誌   9 ( 6 )   655 - 660   2004.12( ISSN:1344-6703

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  • Evaluation of new drug delivery system for rhBMP-2 in a rabbit lumbar spine fusion model. Reviewed

    Namikawa T, Terai H, Suzuki E, Hoshino A, Toyoda H, Nakamura H, Miyamoto S, Takaoka K

    JOURNAL OF BONE AND MINERAL RESEARCH   19   S208 - S208   2004.10( ISSN:0884-0431

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  • Up-regulation of bone morphogenetic protein receptors induced by hepatocyte growth factor in the early phase of fracture repair. Reviewed

    Imai Y, Terai H, Nomura-Furuwatari C, Matsumoto K, Nakamura T, Takaoka K

    JOURNAL OF BONE AND MINERAL RESEARCH   19   S217 - S217   2004.10( ISSN:0884-0431

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  • Repair of intercalated long bone defect with biodegradable beta-tricalcium phosphate added by a new delivery system for recombinant human bone morphogenetic protein-2. Reviewed

    Yoneda M, Terai H, Miyamoto S, Takaoka K

    JOURNAL OF BONE AND MINERAL RESEARCH   19   S347 - S347   2004.10( ISSN:0884-0431

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  • Local release of a prostanoid receptor EP4 agonist with rhBMP-2 enhances bone morphogenctic protein-induced bone formation. Reviewed

    Toyoda H, Terai H, Sasaoka R, Oda K, Takaoka K

    JOURNAL OF BONE AND MINERAL RESEARCH   19   S147 - S147   2004.10( ISSN:0884-0431

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  • A new bone-inducing biodegradable porous beta-tricalcium phosphate Reviewed

    Matsushita N, Terai H, Okada T, Nozaki K, Inoue H, Miyamoto S, Takaoka K

    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A   70A ( 3 )   450 - 458   2004.09( ISSN:1549-3296

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    DOI: 10.1002/jbm.a.30102

  • A new bone-inducing biodegradable porous beta-tricalcium phosphate. Reviewed

    Matsushita N, Terai H, Okada T, Nozaki K, Inoue H, Miyamoto S, Takaoka K

    Journal of biomedical materials research. Part A   70 ( 3 )   450 - 8   2004.09( ISSN:1549-3296

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    DOI: 10.1002/jbm.a.30102

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  • Does chronic cervical myelopathy affect respiratory function? Reviewed

    Toyoda H, Nakamura H, Konishi S, Terai H, Takaoka K

    Journal of neurosurgery. Spine   1 ( 2 )   175 - 8   2004.09( ISSN:1547-5654

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    DOI: 10.3171/spi.2004.1.2.0175

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  • Does chronic cervical myelopathy affect respiratory function? Reviewed

    Toyoda H, Nakamura H, Konishi S, Terai H, Takaoka K

    JOURNAL OF NEUROSURGERY-SPINE   1 ( 2 )   175 - 178   2004.09( ISSN:1547-5654

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  • Does chronic cervical myelopathy affect respiratory function? Reviewed

    Toyoda H, Nakamura H, Konishi S, Terai H, Takaoka K

    Journal of neurosurgery. Spine   1 ( 2 )   175 - 8   2004.09( ISSN:1547-5654

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    DOI: 10.3171/spi.2004.1.2.0175

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  • A prostanoid receptor EP4 agonist enhances ectopic bone formation induced by recombinant human bone morphogenetic protein-2 Reviewed

    Sasaoka R, Terai H, Toyoda H, Imai Y, Sugama R, Takaoka K

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   318 ( 3 )   704 - 709   2004.06( ISSN:0006-291X

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    DOI: 10.1016/j.bbrc.2004.04.080

  • A prostanoid receptor EP4 agonist enhances ectopic bone formation induced by recombinant human bone morphogenetic protein-2. Reviewed

    Sasaoka R, Terai H, Toyoda H, Imai Y, Sugama R, Takaoka K

    Biochemical and biophysical research communications   318 ( 3 )   704 - 9   2004.06( ISSN:0006-291X

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    DOI: 10.1016/j.bbrc.2004.04.080

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  • Evaluation of speech intelligibility after a secondary dehiscence operation using an artificial graft in patients with speech disorders after partial glossectomy. Reviewed

    Terai H, Shimahara M

    The British journal of oral & maxillofacial surgery   42 ( 3 )   190 - 4   2004.06( ISSN:0266-4356

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    DOI: 10.1016/j.bjoms.2004.02.007

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  • Balloon kyphoplasty for pseudoarthrosis following osteoporotic vertebral fracture Reviewed

    HOSHINO M.

    15 ( 1 )   2004.05( ISSN:13464876

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  • The relationship between the area of spinal cord, dural sac and clinical results after cervical laminoplasty Reviewed

    TOYODA H.

    15 ( 1 )   2004.05( ISSN:13464876

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  • Shortening of the duration administrating antibiotic prophylaxis in spine surgery Reviewed

    SUZUKI A.

    15 ( 1 )   2004.05( ISSN:13464876

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  • A study on MRI findings for microscopic bilateral decompression via unilateral approach for lumbar spinal canal stenosis Reviewed

    NAMIKAWA T.

    15 ( 1 )   2004.05( ISSN:13464876

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  • A novel diagnosis method and operative therapy for OALL patients with dysphagia : A clinical case report of two patients who underwent pharyngoesophageal function testing and ostectomy using 3-D modeling of cervical spine Reviewed

    TERAI H.

    15 ( 1 )   2004.05( ISSN:13464876

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  • Shortening of the duration administrating antibiotic prophylaxis in spine surgery Reviewed

    SUZUKI A.

    15 ( 1 )   50   2004.05( ISSN:13464876

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  • Balloon kyphoplasty for pseudoarthrosis following osteoporotic vertebral fracture Reviewed

    HOSHINO M.

    15 ( 1 )   195   2004.05( ISSN:13464876

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  • The relationship between the area of spinal cord, dural sac and clinical results after cervical laminoplasty Reviewed

    TOYODA H.

    15 ( 1 )   290   2004.05( ISSN:13464876

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  • A novel diagnosis method and operative therapy for OALL patients with dysphagia : A clinical case report of two patients who underwent pharyngoesophageal function testing and ostectomy using 3-D modeling of cervical spine Reviewed

    TERAI H.

    15 ( 1 )   179   2004.05( ISSN:13464876

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  • A study on MRI findings for microscopic bilateral decompression via unilateral approach for lumbar spinal canal stenosis Reviewed

    NAMIKAWA T.

    15 ( 1 )   94   2004.05( ISSN:13464876

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  • Osteophytectomy through Anterior Approach for Ossification of the Anterior Longitudinal Ligaments of the Cervical Spine Associated with Dysphagia Reviewed

    FUJIWARA Y., OSUGI H., TAKEMURA M., LEE S., KANEKO K., TANAKA Y., NISHIZAWA S., IWASAKI H., TERAI H., NAKAMURA H., TAKAOKA K.

    55 ( 2 )   155 - 156   2004.04( ISSN:00290645

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  • Osteophytectomy through Anterior Approach for Ossification of the Anterior Longitudinal Ligaments of the Cervical Spine Associated with Dysphagia Reviewed

    FUJIWARA Y., OSUGI H., TAKEMURA M., LEE S., KANEKO K., TANAKA Y., NISHIZAWA S., IWASAKI H., TERAI H., NAKAMURA H., TAKAOKA K.

    55 ( 2 )   155 - 156   2004.04( ISSN:00290645

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  • 【骨形成の分子医学】BMPによる骨形成の制御 Reviewed

    寺井 秀富, 高岡 邦夫

    Medical Science Digest   30 ( 3 )   91 - 94   2004.03( ISSN:1347-4340

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  • Closed treatment of condylar fractures by intermaxillary fixation with thermoforming plates. Reviewed

    Terai H, Shimahara M

    The British journal of oral & maxillofacial surgery   42 ( 1 )   61 - 3   2004.02( ISSN:0266-4356

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    DOI: 10.1016/s0266-4356(03)00205-5

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  • Diagnostic value of abnormal Q waves for identification of preclinical carriers of hypertrophic cardiomyopathy based on a molecular genetic diagnosis. Reviewed

    Konno T, Shimizu M, Ino H, Yamaguchi M, Terai H, Uchiyama K, Oe K, Mabuchi T, Kaneda T, Mabuchi H

    European heart journal   25 ( 3 )   246 - 51   2004.02( ISSN:0195-668X

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    DOI: 10.1016/j.ehj.2003.10.031

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  • Osteoclastogenesis on tissue-engineered bone. Reviewed

    Nakagawa K, Abukawa H, Shin MY, Terai H, Troulis MJ, Vacanti JP

    Tissue engineering   10 ( 1-2 )   93 - 100   2004.01( ISSN:1076-3279

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    DOI: 10.1089/107632704322791736

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  • Osteophytectomy through Anterior Approach for Ossification of the Anterior Longitudinal Ligaments of the Cervical Spine Associated with Dysphagia Reviewed

    Fujiwara Y., Nakamura H., Takaoka K., Osugi H., Takemura M., Lee S., Kaneko K., Tanaka Y., Nishizawa S., Iwasaki H., Terai H.

    The Japan Broncho-esophagological Society, Nihon Kikan Shokudoka Gakkai Kaiho   55 ( 2 )   155 - 156   2004( ISSN:0029-0645

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    DOI: 10.2468/jbes.55.155

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  • Up regulation of bone morphogenetic protein receptors induced by hepatocyte growth factor Reviewed

    Imai Y, Terai H, Nomura C, Takaoka K

    BONE   34   S7 - S7   2004( ISSN:8756-3282

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  • Osteophytectomy through Anterior Approach for Ossification of the Anterior Longitudinal Ligaments of the Cervical Spine Associated with Dysphagia

    Fujiwara Y., Osugi H., Takemura M., Lee S., Kaneko K., Tanaka Y., Nishizawa S., Iwasaki H., Terai H., Nakamura H., Takaoka K.

    Nihon Kikan Shokudoka Gakkai Kaiho   55 ( 2 )   155 - 156   2004( ISSN:00290645 ( eISSN:18806848

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    DOI: 10.2468/jbes.55.155

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  • Aerobic ruthenium-catalyzed oxidative cyanation of tertiary amines with sodium cyanide. Reviewed

    Murahashi S, Komiya N, Terai H, Nakae T

    Journal of the American Chemical Society   125 ( 50 )   15312 - 3   2003.12( ISSN:0002-7863

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    DOI: 10.1021/ja0390303

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  • Neurological disorders requiring differential diagnosis in the field of orthopaedic clinic : a report of 4 cases Reviewed

    KYOH Yoshinori, OSAWA Masahide, TANAKA Naofumi, TERAI Hidetomi, KONISHI Sadahiko, NAKAMURA Hiroaki, FU Takeshi

    14 ( 2 )   185 - 188   2003.12( ISSN:09176772

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  • Neurological disorders requiring differential diagnosis in the field of orthopaedic clinic : a report of 4 cases Reviewed

    KYOH Yoshinori, OSAWA Masahide, TANAKA Naofumi, TERAI Hidetomi, KONISHI Sadahiko, NAKAMURA Hiroaki, FU Takeshi

    14 ( 2 )   185 - 188   2003.12( ISSN:09176772

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  • 整形外科外来にて鑑別診断を要した4神経障害の報告 Reviewed

    姜 良勲, 大沢 正秀, 田中 直史, 寺井 秀富, 小西 定彦, 中村 博亮, 夫 猛

    末梢神経   14 ( 2 )   185 - 188   2003.12( ISSN:0917-6772

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    神経障害で整形外科を紹介受診したが,鑑別診断に苦慮した4例を経験した.症例1(66歳男).徐々に左下肢が動きにくくなった.強い拍動性の前頭部痛を認めた.ピリン・カフェイン合剤投薬後,頭痛消退した.血管攣縮よる片麻痺型片頭痛と診断した.症例2(19歳女).両下肢麻痺,尿閉,複視で受診した.急性散在性脳脊髄炎と診断した.ステロイド療法でほぼ寛解した.症例3(23歳女).右上肢浮腫,運動・知覚麻痺で受診した.右上肢弾性包帯を使用し,輸液,アスピリン配合剤,塩酸サルポグレラートを投与した.胸郭出口症候群の一亜型で原発性鎖骨下静脈血栓症と診断した.症例4(51歳男).右上肢運動・知覚障害,頸部・右肩甲上腕痛で受診した.ノイロトロピン,PGE1を投与し,痛みは消失した.パンコースト腫瘍と診断した

  • Autopsy findings in siblings with hypertrophic cardiomyopathy caused by Arg92Trp mutation in the cardiac troponin T gene showing dilated cardiomyopathy-like features. Reviewed

    Shimizu M, Ino H, Yamaguchi M, Terai H, Uchiyama K, Inoue M, Ikeda M, Kawashima A, Mabuchi H

    Clinical cardiology   26 ( 11 )   536 - 9   2003.11( ISSN:0160-9289

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    DOI: 10.1002/clc.4960261112

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  • Changes in cardiac sympathetic nerve innervation and activity in pathophysiologic transition from typical to end-stage hypertrophic cardiomyopathy. Reviewed

    Terai H, Shimizu M, Ino H, Yamaguchi M, Uchiyama K, Oe K, Nakajima K, Taki J, Kawano M, Mabuchi H

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine   44 ( 10 )   1612 - 7   2003.10( ISSN:0161-5505

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  • 下肢疼痛と筋力低下,間欠跛行を呈した腰部脊柱管狭窄症の1例 Reviewed

    寺井 秀富

    新薬と臨牀   52 ( 10 )   1406 - 1408   2003.10( ISSN:0559-8672

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    54歳女.右下肢に痛を自覚し,腰部脊柱管狭窄症と診断された.NSAIDs服用で経過観察中であったが,疼痛の軽快と増悪を繰り返した.右下肢疼痛の増強,筋力の低下及び10分程度の間欠跛行が出現した.MRIでL4椎体前方すべり,L5/S1での椎間腔狭小化と脊柱管の狭窄が認められた.動態撮影でL4椎体の不安定性は認めなかった.リマプロストの経口投与とNSAIDsの頓用を開始した.投与開始2週後,繰り返していた歩行時の痛みの程度が軽減し,安静時の倦怠感としびれも気にならない程度にまで改善した.投与開始4週後には疼痛が消失した.6週後からはリマプロスト単剤で経過観察を開始し,8週後には右下肢筋力の改善が認められ,30分以上の歩行が可能となった.以後,経過観察中であるが,痛みは完全に消失し,筋力も回復して現在では趣味のバレーボールも可能である.尚,リマプロスト投与中に副作用は認められなかった

  • 腰椎椎間板ヘルニアに対するMicro Endoscopic Discectomyの成績と侵襲度評価 Reviewed

    笹岡 隆一, 中村 博亮, 小西 定彦, 鈴木 英介, 寺井 秀富, 豊田 宏光, 高岡 邦夫

    骨・関節・靱帯   16 ( 10 )   1283 - 1288   2003.10( ISSN:0915-1125

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    腰椎椎間板ヘルニアに対するMicroendoscopic discectomy(顕微内視鏡下椎間板切除術;以下MED)施行15例とMicrodiscectomy(顕微鏡視下椎間板切除術;以下Micro)施行10例を対象に手術侵襲度の群間比較を行った.手術時間には有意差なく,出血量はMED群が少なかった.術翌日の白血球数,CRP値に有意差なく,CPK値はMicro群が,炎症性サイトカイン値はMED群が低かった.これら結果からMEDは侵襲度の低い術式であることが示された

  • Bone formation induced by bone morphogenetic protein is stimulated by prostaglandin E EP4 receptor agonist in its early phase. Reviewed

    Hiromitsu T, Terai H, Sasaoka R, Imai Y, Sugama R, Takaoka K

    JOURNAL OF BONE AND MINERAL RESEARCH   18   S186 - S186   2003.09( ISSN:0884-0431

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  • Prostaglandin E EP4 receptor agonist enhances ectopic bone formation induced by rhBMIP-2. Reviewed

    Terai H, Sasaoka R, Toyoda H, Imai Y, Sugama R, Takaoka K

    JOURNAL OF BONE AND MINERAL RESEARCH   18   S185 - S185   2003.09( ISSN:0884-0431

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  • A new acellular vascular prosthesis as a scaffold for host tissue regeneration. Reviewed

    Tamura N, Nakamura T, Terai H, Iwakura A, Nomura S, Shimizu Y, Komeda M

    The International journal of artificial organs   26 ( 9 )   783 - 92   2003.09( ISSN:0391-3988

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  • QT dispersion and left ventricular morphology in patients with hypertrophic cardiomyopathy. Reviewed

    Sakata K, Shimizu M, Ino H, Yamaguchi M, Terai H, Hayashi K, Kiyama M, Hayashi T, Inoue M, Mabuchi H

    Heart (British Cardiac Society)   89 ( 8 )   882 - 6   2003.08( ISSN:1355-6037

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    DOI: 10.1136/heart.89.8.882

    PubMed

  • 腰椎椎間板ヘルニアに対するmicroendoscopic discectomy(MED)術後1年以上経過例の画像的変化について Microdiscectomyとの比較検討 Reviewed

    笹岡 隆一, 中村 博亮, 小西 定彦, 鈴木 英介, 寺井 秀富, 高岡 邦夫

    脊椎・脊髄神経手術手技   5 ( 1 )   28 - 30   2003.08

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    後方進入内視鏡下椎間板切除術後1年以上経過した23例(MED群)の画像的変化を,microdiscectomy施行後同じく1年以上経過した19例(Micro群)を対照とし,検討した.術前および術後1年以上経過時の単純X線像において上位椎体および椎間板高を測定,椎間板高比を求め評価したところ,椎間板高比(術前/術後)はMED群で平均91.2%,Micro群で平均88.2%となり,両群間に有意差は認めなかった.罹患椎間,年齢,性別の各項目別の椎間板高比においても,両術式間に有意差はなかった.一方,摘出髄核量と椎間板高比には弱い相関を認め,特に2g以上摘出例において椎間板高比が低下する傾向にあった.術後経過期間については,相関はないものの,椎間板高比が低下している症例は術後2年までに多数存在していた

  • Prostaglandin E EP4 receptor agonist (ONO-4819)はrhBMP-2による骨形成作用を促進する Reviewed

    寺井 秀富, 笹岡 隆一, 豊田 宏光, 今井 祐記, 洲鎌 亮, 高岡 邦夫

    日本骨形態計測学会雑誌 = Journal of Japanese Society of Bone Morphometry   13 ( 2 )   2003.05( ISSN:09174648

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    CiNii Article

  • Prostaglandin E EP4 receptor agonist (ONO-4819)はrhBMP-2による骨形成作用を促進する Reviewed

    寺井 秀富, 笹岡 隆一, 豊田 宏光, 今井 祐記, 洲鎌 亮, 高岡 邦夫

    日本骨形態計測学会雑誌 = Journal of Japanese Society of Bone Morphometry   13 ( 2 )   S25   2003.05( ISSN:09174648

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    CiNii Article

  • A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Reviewed

    Yoshimoto H, Shin YM, Terai H, Vacanti JP

    Biomaterials   24 ( 12 )   2077 - 82   2003.05( ISSN:0142-9612

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    DOI: 10.1016/s0142-9612(02)00635-x

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  • A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Reviewed

    Yoshimoto H, Shin YM, Terai H, Vacanti JP

    Biomaterials   24 ( 12 )   2077 - 82   2003.05( ISSN:0142-9612

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    DOI: 10.1016/s0142-9612(02)00635-x

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  • Cardiac sympathetic nerve activity in patients with hypertrophic cardiomyopathy with malignant ventricular tachyarrhythmias. Reviewed

    Terai H, Shimizu M, Ino H, Yamaguchi M, Hayashi K, Sakata K, Kiyama M, Hayashi T, Inoue M, Taki J, Mabuchi H

    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology   10 ( 3 )   304 - 10   2003.05( ISSN:1071-3581

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    DOI: 10.1016/s1071-3581(03)00362-3

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  • Clinical and electrophysiological characterization of a novel mutation (F193L) in the KCNQ1 gene associated with long QT syndrome. Reviewed

    Yamaguchi M, Shimizu M, Ino H, Terai H, Hayashi K, Mabuchi H, Hoshi N, Higashida H

    Clinical science (London, England : 1979)   104 ( 4 )   377 - 82   2003.04( ISSN:0143-5221

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    DOI: 10.1042/CS20020152

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  • A novel missense mutation in the myosin binding protein-C gene is responsible for hypertrophic cardiomyopathy with left ventricular dysfunction and dilation in elderly patients. Reviewed

    Konno T, Shimizu M, Ino H, Matsuyama T, Yamaguchi M, Terai H, Hayashi K, Mabuchi T, Kiyama M, Sakata K, Hayashi T, Inoue M, Kaneda T, Mabuchi H

    Journal of the American College of Cardiology   41 ( 5 )   781 - 6   2003.03( ISSN:0735-1097

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    DOI: 10.1016/s0735-1097(02)02957-1

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  • A radiological study on lumbar spine for physical worker with lumbar spondylolisthesis Reviewed

    NAGAYAMA R.

    14 ( 1 )   2003.02( ISSN:13464876

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    CiNii Article

  • Effect of the respiratory function with cervical myelopathy Reviewed

    TOYODA H.

    14 ( 1 )   2003.02( ISSN:13464876

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    CiNii Article

  • Evaluation for the endoscopic anterior lumbar interbody fusion Reviewed

    SUGAMA R.

    14 ( 1 )   2003.02( ISSN:13464876

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  • A prospective study concerning epidural injection using epidurography : Is it true trained surgeon could give a better injection effect to patients? Reviewed

    TERAI H.

    14 ( 1 )   2003.02( ISSN:13464876

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    CiNii Article

  • The radiographic evaluation of operated intervertebral discs after MicroEndoscopic discectomy (MED) for lumbar disc herniation Reviewed

    SASAOKA R.

    14 ( 1 )   2003.02( ISSN:13464876

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    CiNii Article

  • A radiographic study on operative segment after bilateral decompression with hemilaminotomy Reviewed

    KONISHI S.

    14 ( 1 )   2003.02( ISSN:13464876

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  • The recovery after surgery for cervical myelopathy(compared with the duration of myelopathy) Reviewed

    SUZUKI E.

    14 ( 1 )   2003.02( ISSN:13464876

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    CiNii Article

  • Evaluation for the endoscopic anterior lumbar interbody fusion Reviewed

    SUGAMA R.

    14 ( 1 )   40   2003.02( ISSN:13464876

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    CiNii Article

  • Effect of the respiratory function with cervical myelopathy Reviewed

    TOYODA H.

    14 ( 1 )   65   2003.02( ISSN:13464876

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    CiNii Article

  • The recovery after surgery for cervical myelopathy(compared with the duration of myelopathy) Reviewed

    SUZUKI E.

    14 ( 1 )   178   2003.02( ISSN:13464876

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    CiNii Article

  • A radiographic study on operative segment after bilateral decompression with hemilaminotomy Reviewed

    KONISHI S.

    14 ( 1 )   274   2003.02( ISSN:13464876

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    CiNii Article

  • The radiographic evaluation of operated intervertebral discs after MicroEndoscopic discectomy (MED) for lumbar disc herniation Reviewed

    SASAOKA R.

    14 ( 1 )   399   2003.02( ISSN:13464876

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    CiNii Article

  • A radiological study on lumbar spine for physical worker with lumbar spondylolisthesis Reviewed

    NAGAYAMA R.

    14 ( 1 )   397   2003.02( ISSN:13464876

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    CiNii Article

  • A prospective study concerning epidural injection using epidurography : Is it true trained surgeon could give a better injection effect to patients? Reviewed

    TERAI H.

    14 ( 1 )   35   2003.02( ISSN:13464876

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    CiNii Article

  • Delivery of a growth factor fusion protein having collagen-binding activity to wound tissues. Reviewed

    Ishikawa T, Terai H, Yamamoto T, Harada K, Kitajima T

    Artificial organs   27 ( 2 )   147 - 54   2003.02( ISSN:0160-564X

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    DOI: 10.1046/j.1525-1594.2003.07009.x

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  • Formation of a mandibular condyle in vitro by tissue engineering. Reviewed

    Abukawa H, Terai H, Hannouche D, Vacanti JP, Kaban LB, Troulis MJ

    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons   61 ( 1 )   94 - 100   2003.01( ISSN:0278-2391

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    DOI: 10.1053/joms.2003.50015

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  • Effects of gender on the number of diseased vessels and clinical outcome in Japanese patients with acute coronary syndrome. Reviewed

    Oe K, Shimizu M, Ino H, Yamaguchi M, Terai H, Hayashi K, Kiyama M, Sakata K, Hayashi T, Inoue M, Kaneda T, Mabuchi H

    Circulation journal : official journal of the Japanese Circulation Society   66 ( 5 )   435 - 40   2002.05( ISSN:1346-9843

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    DOI: 10.1253/circj.66.435

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  • Chronologic electrocardiographic changes in patients with hypertrophic cardiomyopathy associated with cardiac troponin 1 mutation. Reviewed

    Shimizu M, Ino H, Yamaguchi M, Terai H, Hayashi K, Kiyama M, Sakata K, Hayashi T, Inoue M, Kaneda T, Mabuchi H

    American heart journal   143 ( 2 )   289 - 93   2002.02( ISSN:0002-8703

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    DOI: 10.1067/mhj.2002.119760

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  • Biodegradation of photosynthetically produced extracellular organic carbon from intertidal benthic algae. Reviewed

    Goto N, Mitamura O, Terai H

    Journal of experimental marine biology and ecology   257 ( 1 )   73 - 86   2001.02( ISSN:0022-0981

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    DOI: 10.1016/s0022-0981(00)00329-4

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  • 頸椎前方固定における絹糸を用いた移植骨固定法の工夫 Reviewed

    寺井 秀富, 中村 博亮, 関 昌彦, 小西 定彦, 山野 慶樹

    脊椎・脊髄神経手術手技   2 ( 1 )   35 - 36   2000.08

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    頸椎前方固定に際し絹糸を用いた移植骨の固定は,簡便な方法で移植骨の脱転予防に有用であり,術後療法の短縮が可能であった

  • Articulatory function in patients who have undergone glossectomy with use of an artificial graft membrane. Reviewed

    Terai H, Shimahara M

    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics   89 ( 5 )   560 - 2   2000.05( ISSN:1079-2104

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    DOI: 10.1067/moe.2000.104069

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  • 外傷治療のControversies 骨折 骨盤骨折 骨盤輪骨折の骨折型と創外固定法 Reviewed

    寺井 秀富, 山野 慶樹

    別冊整形外科   ( 37 )   58 - 63   2000.04( ISSN:0287-1645

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  • Outcome of Second Revision THR Reviewed

    OHASHI Hirotsugu

    Japanese Society for Joint Diseases, Japanese Journal of Rheumatism and Joint Surgery   18 ( 4 )   199 - 204   2000.03( ISSN:02873214

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    The outcome of second revision total hip arthroplasties (THA) was investigated. There were 15 hips with a follow-up period of over one year. The average age at primary THA was 48.5 years, average age at revision THA was 55.1 years, and average age at second revision THA was 65.3 years. All revisions were performed using a cemented THA. In second revision THA, an allograft was used in 4 hips, a morsellized allograft was impacted in 2, and hydroxyapatite granules were impacted in 2 to treat the acetabular bone defects. For femoral bone defects, a long stem was used in 9 hips and a morsellized allograft was impacted in 2. One hip underwent a third revision THA due to aseptic loosening. One hip suffered from infection and one-stage revision was performed. One hip revealed radiological loosening. The other 12 hips did not show loosening. The average JOA score at final follow-up was 71.9 points. The average scores for pain, walking, range of motion, and activity of daily living were 36.4, 10.9, 12.5 and 11.5, respectively. These results indicate that second revision THA is effective to relieve pain, while the activity of daily living of patients after second revision THA is limited. It is suggested that good timing for revision THA and precise operative technique are important to improve the outcome of revision THA.

    DOI: 10.11551/jsjd1982.18.199

    CiNii Article

  • THR再々置換術の成績と問題点 Reviewed

    大橋 弘嗣, 格谷 義徳, 箕田 行秀, 寺井 秀富, 山野 慶樹

    日本リウマチ・関節外科学会雑誌   18 ( 4 )   199 - 204   2000.03( ISSN:0287-3214

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    疼痛,X線像はほぼ満足できる結果であった.しかし,歩行能力,可動域,日常生活動作の点数が低く,活動能力が低下していると考えられた.再置換術,再々置換術の成績向上のためには適切な手術時期の決定,的確な手術方法が重要であると考えられた

  • Anterior Decompression and Fusion with Folded Vascularized Rib Graft Reviewed

    KONISHI S.

    74 ( 2 )   2000.02( ISSN:00215325

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  • Microendoscopic Discectomy for Lumbar Disc Herniation Reviewed

    NAKAMURA H.

    74 ( 2 )   S141   2000.02( ISSN:00215325

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  • Anterior Decompression and Fusion with Folded Vascularized Rib Graft Reviewed

    KONISHI S.

    74 ( 2 )   S419   2000.02( ISSN:00215325

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    CiNii Article

  • 低リン血症性くる病における下肢変形に対するイリザロフ矯正中の骨塩量の変化 Reviewed

    榎本 誠, 北野 利夫, 中塚 洋直, 中川 滋, 寺井 秀富, 酒井 俊幸, 中野 元博, 山野 慶樹

    近畿小児整形外科   12   39 - 42   1999.09( ISSN:1345-1154

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  • Anti-tumor polysaccharide from the mycelium of liquid-cultured Agaricus blazei mill. Reviewed

    Mizuno M, Minato K, Ito H, Kawade M, Terai H, Tsuchida H

    Biochemistry and molecular biology international   47 ( 4 )   707 - 14   1999.04( ISSN:1039-9712

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    DOI: 10.1080/15216549900201773

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  • Autolysis of lentinan, an antitumor polysaccharide, during storage of Lentinus edodes, shiitake mushroom. Reviewed

    Minato K, Mizuno M, Terai H, Tsuchida H

    Journal of agricultural and food chemistry   47 ( 4 )   1530 - 2   1999.04( ISSN:0021-8561

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    DOI: 10.1021/jf981022w

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  • 腹腔鏡を応用した腰椎前方固定術の経験 Reviewed

    中村 博亮, 関 昌彦, 小西 定彦, 長山 隆一, 寺井 秀富, 山野 慶樹

    日本整形外科學會雜誌 = The Journal of the Japanese Orthopaedic Association   73 ( 3 )   1999.03( ISSN:00215325

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    CiNii Article

  • 腹腔鏡を応用した腰椎前方固定術の経験 Reviewed

    中村 博亮, 関 昌彦, 小西 定彦, 長山 隆一, 寺井 秀富, 山野 慶樹

    日本整形外科學會雜誌 = The Journal of the Japanese Orthopaedic Association   73 ( 3 )   S604   1999.03( ISSN:00215325

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    CiNii Article

  • カラーフォーラム 下腿コンパートメント症候群の視診的特徴 Reviewed

    寺井 秀富, 高松 聖仁, 山野 慶樹

    整形外科   50 ( 1 )   90 - 91   1999.01( ISSN:0030-5901

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  • Outcome of Second Revision THR Reviewed

    OHASHI Hirotsugu

    Japanese Journal of Rheumatism and Joint Surgery   18 ( 4 )   199 - 204   1999( ISSN:02873214 ( eISSN:18849059

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    The outcome of second revision total hip arthroplasties (THA) was investigated. There were 15 hips with a follow-up period of over one year. The average age at primary THA was 48.5 years, average age at revision THA was 55.1 years, and average age at second revision THA was 65.3 years. All revisions were performed using a cemented THA. In second revision THA, an allograft was used in 4 hips, a morsellized allograft was impacted in 2, and hydroxyapatite granules were impacted in 2 to treat the acetabular bone defects. For femoral bone defects, a long stem was used in 9 hips and a morsellized allograft was impacted in 2. One hip underwent a third revision THA due to aseptic loosening. One hip suffered from infection and one-stage revision was performed. One hip revealed radiological loosening. The other 12 hips did not show loosening. The average JOA score at final follow-up was 71.9 points. The average scores for pain, walking, range of motion, and activity of daily living were 36.4, 10.9, 12.5 and 11.5, respectively. These results indicate that second revision THA is effective to relieve pain, while the activity of daily living of patients after second revision THA is limited. It is suggested that good timing for revision THA and precise operative technique are important to improve the outcome of revision THA.

    DOI: 10.11551/jsjd1982.18.199

    CiNii Article

  • [Case of malignant lymphoma with bilateral lung lesions and myositis]. Reviewed

    Yutsudo J, Amano K, Terai H, Nishi K, Murase M, HosomiY, Fukui N, Yoshihara Y, Tanaka Y, Yamashita M, Shiozawa K

    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine   86 ( 12 )   2306 - 8   1997.12( ISSN:0021-5384

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  • [Pheochromocytoma of the left retroperitoneal paraganglion associated with torsade de pointes: a case report]. Reviewed

    Kihara H, Terai H, Kihara Y, Kihara T, Takahashi H, Kosuda A, Shimomoto M, Fukunishi M, Tanaka T

    Journal of cardiology   30 ( 1 )   37 - 44   1997.07( ISSN:0914-5087

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  • [Primary right atrial hemangiosarcoma manifesting as cardiac tamponade: a case report with transesophageal echocardiography]. Reviewed

    Kihara H, Terai H, Kihara Y, Ito T, Hirasawa K, Tateda K, Ishibashi Y, Aoki H, Murakami T, Kanda M, Shibata T

    Journal of cardiology   27 ( 6 )   329 - 33   1996.06( ISSN:0914-5087

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  • [A case of aortic bicuspid valvular endocarditis with congenital left ventricular diverticulum]. Reviewed

    Kihara H, Terai H, Kihara Y, Ishibashi Y, Sudo Y, Tada Y, Miyatake T, Aoki H, Murakami T, Kanda M

    Journal of cardiology   26 ( 5 )   299 - 303   1995.11( ISSN:0914-5087

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Industrial Property Rights

  • 医療用ボルト

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    Application no:特願2021-072687 

  • 内視鏡洗浄セット、内視鏡先端面用クリーナー、及び内視鏡先端面用ワイパー

    寺井 秀富

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    property_type:Patent 

    Application no:特願2013-73371 

  • Multilayer device for tissue engineering

    Jeffrey T. Borenstein, Kevin R. King, Hidetomi Terai, Joseph P. Vacanti

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    property_type:Patent 

    Application no:US7371400B2 

  • Tissue Engineering of Three-Dimensional Vascularized using Microfabricated Polymer Assembly Technology

    Jeffrey Borenstein, Kevin King, Joseph P. Vacanti, Hidetomi Terai

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    Application no:WO2002053193A3 

Grant-in-Aid for Scientific Research

  • Basic science study of the impact of heated tobacco cessation on the bone healing

    Grant-in-Aid for Scientific Research(C)  2025

  • 徐放性骨軟化ゲルを用いた骨変形・脊柱変形の治療

    Grant-in-Aid for Scientific Research(C)  2024

  • Basic science study of the impact of heated tobacco cessation on the bone healing

    Grant-in-Aid for Scientific Research(C)  2024

Outline of education staff

  • 整形外科学、脊椎外科

Charge of on-campus class subject

  • Practice in Clinical Study of Rheumatosurgery

    2024     Graduate school

  • Pathophysiology in Rheumatosurgery

    2024     Graduate school

  • Diagnostic Method in Rheumatosurgery

    2024     Graduate school

  • Treatment Options in Rheumatosurgery

    2024     Graduate school

  • Practice in Clinical Study of Orthopaedic Surgery

    2024     Graduate school

  • Pathophisiology in Orthopaedic Surgery

    2024     Graduate school

  • Diagnostic Method in Orthopaedic Surgery

    2024     Graduate school

  • Treatment Options in Orthopaedic Surgery

    2024     Graduate school

  • Basic Course of Clinical Medicine

    2024     Graduate school

  • 整形外科学1

    2024   Weekly class   Undergraduate

  • 脊椎外科学

    2018     Graduate school

  • 脊椎外科学

    2018     Undergraduate

  • 整形外科学

    2018     Undergraduate

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Charge of off-campus class subject

  • 修士課程講義

Faculty development activities

  • FD活動への貢献  2017

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    FD活動講演

Number of instructed thesis, researches

  • 2018

    Number of instructed the graduation thesis:

    [Number of instructed the Master's Program] (previous term):

Original item・Special report (Education Activity)

  • 2017

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    Original item:Afghanistan留学生指導

Social Activities ⇒ Link to the list of Social Activities

  • 難病療養相談

    Role(s): Consultant

    Type: University open house, Cooperation business with The administrative, educational institutions, etc.

    2014.04 - Now

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    Audience: General public, Civic organization

Foreigner acceptance

  • 2017

    foreigners accepted :5

    International Students :5

Other

  • Job Career

    2015.04 - Now

  • Job Career

    2005.04 - 2015.03

  • Job Career

    2002.07 - 2005.03

  • Job Career

    2002.04 - 2002.06

  • Job Career

    1998.04 - 2002.03

  • Job Career

    1997.05 - 1998.03

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