Updated on 2023/09/29

写真a

 
AZUMA Masayuki
 
Organization
Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology Professor
School of Engineering Department of Chemistry and Bioengineering
Title
Professor
Affiliation
Institute of Engineering
Affiliation campus
Sugimoto Campus

Position

  • Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology 

    Professor  2022.04 - Now

  • School of Engineering Department of Chemistry and Bioengineering 

    Professor  2022.04 - Now

Degree

  • Doctor of Agriculture ( The University of Tokyo )

Research Areas

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering  / Bioengineering

  • Life Science / Applied microbiology

  • Nanotechnology/Materials / Chemical biology

Research Interests

  • Microorganism

  • Cell surface

  • Fermentation

  • Cell engineering

  • Microbial fuel cell

  • Yeast

  • Metal absorbent

Research subject summary

  • Investigation of new cell functions focusing on microbes and cell surface, and construction of cells with new functions applied to the medicine, the environment and energy, the food areas

Research Career

  • Cell surface analysis of yeast and application of cell surface mutant strains

    1994 - Now 

  • Studies on useful enzymes produced by microorganisms

    enzyme, microorganism  Joint Research in Japan

    1985 - Now 

  • Studies on biologically active substances produced by microorganisms

    biologically active substance, Microorganism  Joint Research in Japan

    1987 - Now 

  • Study on microbial fuel cell

    2008 - Now 

  • Development of biosurfactant of microbial origin

    2010 - Now 

  • 微生物による金属回収技術の開発

    2008 - Now 

Professional Memberships

  • THE SOCIETY FOR BIOTECHNOLOGY, JAPAN

      Domestic

  • 日本農芸化学会

      Domestic

  • 化学工学会

      Domestic

  • 近畿化学協会

      Domestic

  • バイオインダストリー協会

      Domestic

  • 酵母遺伝学フォーラム

      Domestic

  • 酵母研究会

      Domestic

  • バオ産業研究会

      Domestic

▼display all

Committee Memberships (off-campus)

  • 理事・関西支部長   日本生物工学会  

    2023.06 - Now 

  • 実行委員   日本生物工学会100周年記念大会  

    2021.08 - 2022.10 

  • 基準総合調整委員   日本技術者教育認定機構(JABEE)  

    2021.06 - Now 

  • 副支部長   日本生物工学会  

    2021.06 - 2023.05 

  • 幹事   日本生物工学会培養工学研究部会  

    2020.06 - Now 

  • 代議員   日本生物工学会  

    2019 - Now 

  • 代議員   近畿化学協会  

    2019 - Now 

  • 会長   バイオ産業研究会  

    2019 - Now 

  • 理事   近畿化学協会  

    2017.04 - Now 

  • 実行委員   日本生物工学会2018年度大会  

    2017 - 2018.09 

  • 会計監事   バイオ産業研究会  

    2016 - 2019 

  • 幹事   近畿化学協会バイオ部会  

    2014 - Now 

  • 委員   日本生物工学会JABEE特別部会  

    2014 - Now 

  • 委員   日本生物工学会関西支部  

    2014 - Now 

  • 幹事   化学工学会バイオ部会  

    2014 - Now 

  • 幹事   バイオ産業研究会  

    2014 - 2016 

▼display all

Awards

  • Best Paper Award 2020 (Bioprocess and Biosystems Engineering誌)

    2021.02  

  • Journal of Chemical Engineering of Japan Editor's Choice Price

    2018.05  

Job Career (off-campus)

  • 住友林業(株)   開発企画部 筑波研究所   -研究員 主任研究員

    1987 - 1996

Education

  • Osaka University   Master's Course  

    - 1987

  • Osaka University    

    - 1985

Papers

  • The Identification and Characterization of a New Carbapenem CS-023 SolvatePolymorph Achieved by the Appropriate Crystal Washing and Drying Reviewed

    Shinji Matsuura, Koichi Igarashi, Masayuki Azuma, and Hiroshi Ooshima

    JOURNAL OF CHEMICAL ENGINEERING OF JAPAN   56 ( 1 )   2215255   2023.07

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1080/00219592.2023.2215255

  • Identification of emulsification proteins released from the cells by inhibiting the synthesis of GPI-anchor or β-1,3-glucan in Candida albicans Reviewed

    S. Nerome, M. Tsudzuki, M. Nizuka, M. Takata, Y. Ojima, M. Azuma

    J. Microbiol. Methods   209   106728   2023.06

     More details

    Authorship:Last author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: https://doi.org/10.1016/j.mimet.2023.106728

  • Characterization of self-aggregation in Bacillus lichneniformis strain RK14 Reviewed

    Y. Ojima, S. Matano, M. Azuma

    73   18   2023.05

     More details

    Authorship:Last author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

  • Quantitative analysis of phosphate accumulation in PHO regulatory system-mutant strains of Saccharomyces cerevisiae. Reviewed

    Y. Ojima, K. Naoi, R. Akiyoshi, M. Azuma

    in press   2023.03

     More details

    Authorship:Last author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

  • Adsorption of rare earth ions from synthetic seawater and hot spring water using phosphorylated yeast. Invited Reviewed

    M. Kihara, Y. Ojima, M. Azuma

    30   103093   2023.03

     More details

    Authorship:Last author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: https://doi.org/10.1016/j.eti.2023.103093

  • Concentrative nucleoside transporter, CNT, results in selective toxicity of toyocamycin against Candida albicans. Reviewed

    Y. Ojima, N. Yokota, Y. Tanibata, S. Nerome, M. Azuma

    Microbiol. Spectr.   10 ( 4 )   e01138-22   2022.10

     More details

    Authorship:Last author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: https://doi.org/10.1128/spectrum.01138-22

  • Evaluating β-1,3-glucan synthesis inhibition using emulsion formation asan indicator   Reviewed

    S. Nerome, N. Yokota, Y. Ojima, M. Azuma

    J. Microbiol. Methods   190   106327   2021.09

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Aberrant membrane structures in hypervesiculating Escherichia coli strain ΔmlaEΔnlpI visualized by electron microscopy. Reviewed

    Y. Ojima, T. Sawabe, M. Nakagawa, YO. Tahara, M. Miyata, and M. Azuma

    Frontiers in Microbiology   12   706525   2021.08

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Protein Engineering of D-Succinylase from Cupriavidus sp. for D-Amino Acid Synthesis and the Structural Implications Reviewed

    Y. Sumida, M. Yamasaki, Y. Nishiya, S. Kumagai, T. Yamada, M. Azuma

    Adv. Synth. Catal.   363   4770 - 4778   2021.08

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Polymorphic Crystallization Design to Prevent the Degradation of the β-Lactam Structure of a Carbapenem Reviewed

    S. Matsuura, K. Igarashi, M. Azuma, H. Ooshima

    Crystals   11   931   2021.08

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Identification of yeast-derived emulsification proteins through analyses of proteins distributed into the emulsified phase. Reviewed

    M. Onishi, M. Ueda, D. Saito, M. Takata, Y. Ojima, M. Azuma

    Food Hydrocoll.   112   106321   2021.03

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Enhanced floc formation by degP-deficient Escherichia coli cells in the presence of glycerol Reviewed

    Y. Ojima, H. Honma, M. Otsuka, S. Matano, M. Azuma

    J. Biosci. Bioeng.   131 ( 1 )   33 - 38   2021.01

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Mineralization induced by phosphorylated dry baker’s yeast Reviewed

    Y. Ojima, M. Kihara, M. Yoshida, K. Igarashi, T. Yoshida, M. Azuma

    PLOS ONE   15 ( 9 )   e0239774   2020.09

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Cell surface changes that advance the application of using yeast as a food emulsifier. Reviewed

    Nerome S, Onishi M, Saito D, Mizobuchi A, Ando T, Daira Y, Matsumoto A, Ojima Y, Azuma M.

    Food Chem.   315   126264   2020.01

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Construction of hypervesiculation Escherichia coli strains and application for secretory protein production Reviewed

    Yoshihiro Ojima, Tomomi Sawabe, Katsuya Konami, Masayuki Azuma

    Biotechnol. Bioeng.   117 ( 3 )   701 - 709   2019.12

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Knockout of pgdS and ggt gene changes poly-γ-glutamic acid production in Bacillus licheniformis RK14-46Y. Reviewed

    Ojima, J. Kobayashi, T. Doi, M. Azuma.

    Journal of Biotechnology   304   57 - 62   2019.10

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Promoted performance of microbial fuel cells using Escherichia coli cells with multiple-knockout of central metabolism genes. Reviewed

    Y. Ojima, T. Kawaguchi, S. Fukui, R. Kikuchi, K. Terao, D. Koma, T. Ohmoto, M. Azuma

    Bioproc. Biosyst. Eng.   43   323 - 332   2019.10

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Simultaneous Control of Crystal Habit and Particle Size of Ecabet Sodium Hydrate with Rapid Cooling Crystallization and Temperature Cycling. Reviewed

    M. Kishida, K. Igarashi, M. Azuma, H. Ooshima

    J. Chem. Eng. Jpn.   52 ( 5 )   455 - 464   2019.05

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Recovering metals from aqueous solutions by biosorption onto phosphorylated dry baker's yeast Reviewed

    Ojima Yoshihiro, Kosako Shogo, Kihara Maya, Miyoshi Norikazu, Igarashi Koichi, Azuma Masayuki

    SCIENTIFIC REPORTS   9   225   2019.01( ISSN:2045-2322

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1038/s41598-018-36306-2

  • Inducing flocculation of non-floc-forming Escherichia coli cells (Review) Invited Reviewed

    Ojima Yoshihiro, Azuma Masayuki, Taya Masahito

    WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY   34 ( 12 )   185   2018.12( ISSN:0959-3993

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1007/s11274-018-2563-z

  • Pharmaceutical Microcrystal Formation by Supersaturation Control with an Electrolyte Reviewed

    Kishida Muneki, Igarashi Koichi, Azuma Masayuki, Ooshima Hiroshi

    公益社団法人 化学工学会 JOURNAL OF CHEMICAL ENGINEERING OF JAPAN   51 ( 7 )   609 - 614   2018.07( ISSN:0021-9592

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    <p>Methods to control the particle sizes of active pharmaceutical ingredients were investigated using sodium ecabet (Na-ECA) hydrate, which tends to generate large plate-like crystals, as a model compound. In batch-cooling crystallization in H<sub>2</sub>O, the particle size decreased as the cooling rate was increased. Although the particle size reached 97 µm at a cooling rate of 40°C/h, this may be too large for formulation without further physical processing. A series of semi-batch crystallization experiments was conducted by adding aqueous Na-ECA solution to aqueous NaCl. In these experiments, the particle sizes decreased to less than 7 µm as the NaCl concentration was increased to >1.2% w/w. The particles yielded by semi-batch crystallization showed improved particle size distributions compared to those obtained by the batch-cooling crystallization method. The solubility of Na-ECA hydrate decreased to less than 10% of that in pure water as the NaCl concentration was increased to 3.0% w/w. This solubility change enabled the production of a highly supersaturated environment, allowing facile generation of microcrystals with a narrow particle size distribution.</p>

    DOI: 10.1252/jcej.17we307

    CiNii Article

  • A New Method to Purify Poly-gamma-glutamic Acid Using Gemini Quaternary Ammonium Salts and Characterization of its Ionic Complex Reviewed

    Liu Tao, Nobeshima Hirobumi, Ojima Yoshihiro, Azuma Masayuki

    公益社団法人 化学工学会 JOURNAL OF CHEMICAL ENGINEERING OF JAPAN   51 ( 5 )   431 - 437   2018.05( ISSN:0021-9592

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    <p>Poly-gamma-glutamic acid (γ-PGA) is a water-soluble, nontoxic biodegradable polymer. It is extensively utilized in medicines, foodstuffs, and cosmetics, as well as in water treatment. Highly pure γ-PGA is required for various purposes. In many cases, γ-PGA is produced by microbes of <i>Bacillus</i> sp. However, an increase in the viscosity of the culture broth is one of the major problems of γ-PGA production, as higher viscosity makes the separation and purification steps difficult. Herein, we propose a novel method to obtain pure γ-PGA using gemini quaternary ammonium salts (GQASs). The quaternary ammonium cation of GQASs binds to the carboxylic acid group of γ-PGA via an ionic bond, following which water-insoluble and antimicrobial complexes are formed. These complexes are obtained in the aqueous solution, which were resolved in ethanol solution. With an increase in the added amount of GQAS, the negative charge of the complex decreased in the aqueous solution. Subsequently, the GQAS within the complexes was dissociated by the addition of NaCl, affording pure γ-PGA in a high yield. Moreover, the complexes were shown to have antibacterial activity and adhered to glass, indicating that the complex itself has a utility value.</p>

    DOI: 10.1252/jcej.17we218

    CiNii Article

  • Characterization of D-succinylase from Cupriavidus sp. P4-10-C and its application in D-amino acid synthesis. Reviewed

    Sumida Yosuke, Iwai Sachio, Nishiya Yoshiaki, Kumagai Shinya, Yamada Toshihide, Azuma Masayuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   125 ( 3 )   282 - 286   2018.03( ISSN:1389-1723

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.jbiosc.2017.10.007

  • Displaying a recombinant protein on flocs self-produced by Escherichia coli through fused expression with elongation factor Ts Reviewed

    Ojima Yoshihiro, Nunogami Shota, Azuma Masayuki, Taya Masahito

    ENZYME AND MICROBIAL TECHNOLOGY   108   21 - 25   2018.01( ISSN:0141-0229

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1016/j.enzmictec.2017.08.010

  • Behavior of t-Butoxycarbonyl-L-asparagine (Boc-Asn) during the Initial Stage of Crystallization Reviewed

    Igarashi Koichi, Aoki Masako, Masuda Yoshiko, Azuma Masayuki, Ooshima Hiroshi

    JOURNAL OF CHEMICAL ENGINEERING OF JAPAN   51 ( 1 )   111 - 115   2018.01( ISSN:0021-9592

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    <p>The crystallization mechanism of amino acid derivative <i>t</i>-butoxycarbonyl-L-asparagine (Boc-Asn) was investigated. NMR spectroscopy was used to observe the behavior of Boc-Asn molecules in under- and supersaturated solution. Nuclear Overhauser Effect (NOE) NMR measurements were performed to provide information concerning the intra- or intermolecular access of a particular hydrogen atom to other hydrogen atoms in solution. We compared the interactions identified by NOE measurements for under- and supersaturated solutions of Boc-Asn with those in the crystal, as determined by X-ray analysis. According to the X-ray analysis, intramolecular NOE should not be observed, but intermolecular NOE might be observed between the methyl protons of the <i>t</i>-butoxycarbonyl group and the protons belonging to other functional groups. The time course of the NOE intensity was followed for three solutions with different saturation ratios <i>S</i> (=concentration of solute/solubility). For undersaturated and nearly saturated conditions (<i>S</i>=0.8 and 1.12 at 0°C), the NOE intensity did not change for at least for 250 h. However, for the supersaturated solution (<i>S</i>=1.62 at 10°C), the NOE intensity increased suddenly and rapidly after about 120 h, and no crystals were observed during the NOE measurements. As the observed NOEs agreed with those expected from the arrangement of molecules in the crystal, it was suggested that Boc-Asn molecules aggregated after about 120 h with the same structure as that in the crystal. In addition to the behavior of the Boc-Asn solution before nucleation, we also investigated the effect of aggregation on the crystallization process. Solutions that were preincubated at 10°C for various periods were further cooled and crystallized at −30°C. It was found that when the solution was preincubated under the supersaturated condition for a long time before crystallization, nucleation was enhanced, and consequently, the crystal size distribution became homogeneous.</p>

    DOI: 10.1252/jcej.17we027

    CiNii Article

  • Over-expression, characterization, and modification of highly active alkaline phosphatase from a Shewanella genus bacterium Reviewed

    Aiba Hiroshi, Nishiya Yoshiaki, Ojima Yoshihiro, Azuma Masayuki

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   81 ( 10 )   1994 - 2001   2017.10( ISSN:0916-8451

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1080/09168451.2017.1356217

  • Flocculation of Real Sewage Sludge Using Poly-gamma-glutamic Acid Produced by <it>Bacillus</it> sp Isolated from Soil Reviewed

    Liu Tao, Yamashita Kyouhei, Fukumoto Yoshihiro, Tachibana Taro, Azuma Masayuki

    公益社団法人 化学工学会 JOURNAL OF CHEMICAL ENGINEERING OF JAPAN   50 ( 3 )   201 - 206   2017.03( ISSN:0021-9592

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    <p>To promote the use of sewage sludge on farmland, a flocculant compatible with agricultural application is required. In general, an inorganic flocculant such as aluminium sulfate is used at large sewage disposal plants. However, there is concern that aluminium accumulates when it is returned to farmland, and therefore a biodegradable rather than an inorganic flocculant is required. To obtain biodegradable flocculants produced by microorganisms, the latter were isolated from soils and sewage sludges, and the flocculation activity of the culture broths was evaluated. Here, real sewage sludge was used for the evaluation because practical use was regarded as an important consideration. As a result, two strains, V13 and RK14, were selected and identified as <i>Bacillus megaterium</i> and <i>Bacillus licheniformis</i>, respectively. It was also found that flocculation was caused by poly-γ-glutamic acid (γ-PGA). γ-PGA from RK14 cells had considerably higher molecular weight than commercial γ-PGA, and the enantiomeric composition differed from that of γ-PGA from other <i>B. licheniformis</i>. To obtain mutants with high γ-PGA productivity, RK14 cells were treated with ethyl methanesulfonate, and a mutant (RK14-46) was selected. The culture medium suitable for γ-PGA production by RK14-46 cells was totally different from that by RK-14 cells. The γ-PGA production reached 21.1 g/L when RK14-46 cells were cultured in the optimum semi-synthetic medium at 30°C for 2 d. Furthermore, the combination of γ-PGA obtained from RK14-46 cells and chitosan, a cationic flocculant, was very effective for flocculation of real sewage sludge.</p>

    DOI: 10.1252/jcej.16we158

    CiNii Article

  • Identification and Characterization of D-Succinylase, and a Proposed Enzymatic Method for D-Amino Acid Synthesis Reviewed

    Sumida Yosuke, Iwai Sachio, Nishiya Yoshiaki, Kumagai Shinya, Yamada Toshihide, Azuma Masayuki

    ADVANCED SYNTHESIS & CATALYSIS   358 ( 13 )   2041 - 2046   2016.06( ISSN:1615-4150

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1002/adsc.201600105

  • Characterization of a thermostable glucose dehydrogenase with strict substrate specificity from a hyperthermophilic archaeon Thermoproteus sp. GDH-1 Reviewed

    Aiba Hiroshi, Nishiya Yoshiaki, Azuma Masayuki, Yokooji Yuusuke, Atomi Haruyuki, Imanaka Tadayuki

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   79 ( 7 )   1094 - 1102   2015.07( ISSN:0916-8451

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/09168451.2015.1018120

  • Generation and characterization of rat monoclonal antibodies against epidermal growth factor receptor Reviewed

    Tomohiro Osaki, Cai-Xia Wang, Taro Tachibana, Masayuki Azuma, Masaya Kitamura, and Takeshi Nakanishi

    Antib. Immunodiagn. Immunother.   34   418 - 422   2015

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Isolation of diploid baker's yeast capable of strongly activating immune cells and analyses of the cell wall structure Reviewed

    Takada Yuki, Mizobuchi Ayano, Kato Takayuki, Kasahara Emiko, Ito Chinatsu, Watanabe Hajime, Kanzaki Ken, Kitagawa Seiichi, Tachibana Taro, Azuma Masayuki

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   78 ( 5 )   911 - 915   2014.05( ISSN:0916-8451

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/09168451.2014.917259

  • Isolation and characterization of baker's yeast capable of strongly activating a macrophage Reviewed

    Takada Yuki, Nishino Yumiko, Ito Chinatsu, Watanabe Hajime, Kanzaki Ken, Tachibana Taro, Azuma Masayuki

    FEMS YEAST RESEARCH   14 ( 2 )   261 - 269   2014.03( ISSN:1567-1356

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/1567-1364.12098

  • A milliliter-scale yeast-based fuel cell with high performance Reviewed

    Kaneshiro Hiroyuki, Takano Kosuke, Takada Yogo, Wakisaka Tomoyuki, Tachibana Taro, Azuma Masayuki

    BIOCHEMICAL ENGINEERING JOURNAL   83   90 - 96   2014.02( ISSN:1369-703X

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bej.2013.12.011

  • Cell wall structure suitable for surface display of proteins in Saccharomyces cerevisiae Reviewed

    Matsuoka Hiroyuki, Hashimoto Kazuya, Saijo Aki, Takada Yuki, Kondo Akihiko, Ueda Mitsuyoshi, Ooshima Hiroshi, Tachibana Taro, Azuma Masayuki

    YEAST   31 ( 2 )   67 - 76   2014.02( ISSN:0749-503X

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/yea.2995

  • Generation of A Monoclonal Antibody Against the Extracellular Domain of IGF-IR. Reviewed

    Nakadate Y, Yoshimura Y, Nakatani N, Azuma M and Tachibana T.

    Monoclonal Antibodies in Immunodiagnosis and Immunotherapy   33 ( 2 )   126 - 128   2014

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Production of a monoclonal antibody specific for Pou5f1/Oct4. Reviewed

    Tatsuhiko Arakawa,Tomohiko Yoshimi,Masayuki Azuma,and Taro Tachibana

    Monoclon Antib Immunodiagn Immunother.   32 ( 3 )   229 - 231   2013

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • A panel of specific monoclonal antibodies directed against various phosphorylated histone H3. Reviewed

    Yoshimi T., Ohkawa T., Azuma M., Tachibana T.

    Monoclon. Antib. Immunodiagn. Immunother.   32 ( 2 )   119 - 124   2013

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Control of Crystal Size Distribution Using a mL-Scale Continuous Crystallizer Equipped with a High Speed Agitator Reviewed

    Igarashi Koichi, Yamanaka Yasuhiro, Azuma Masayuki, Ooshima Hiroshi

    公益社団法人 化学工学会 JOURNAL OF CHEMICAL ENGINEERING OF JAPAN   45 ( 1 )   28 - 33   2012.03( ISSN:0021-9592

     More details

    Publishing type:Research paper (scientific journal)  

    A mL-scale continuous crystallizer has been newly developed to produce small crystals with a narrow size distribution. The crystallizer is used for the poor solvent crystallization of glycine and <small>L</small>-alanine. The crystallizer is composed of a stainless-steel mixing vessel with an inner volume of 0.9 mL and a high-speed agitator that can agitate the crystallization solution up to 24,000 rpm. Glycine or <small>L</small>-alanine aqueous solution and poor solvent (methanol) are supplied into the vessel at a constant flow rate and intensely mixed by the agitator. The average residence time was set at 0.33, 3.3 and 33 s by changing the flow rate of an amino acid solution and poor solvent. The crystals obtained by the crystallizer are small and uniform in size, comparing with those obtained by a conventional beaker-scale semi-batch and continuous MSMPR type crystallizers. For example, glycine crystals having the 1/38 of the size of crystals obtained by a semi batch crystallizer were obtained. The short residence time that can be attained by the present mL-scale crystallizer is advantageous for the production of small crystals with a narrow size distribution. The size distribution can be further controlled by changing the mixing ratio of poor solvent.

    DOI: 10.1252/jcej.11we158

    CiNii Article

  • Monoclonal Antibody Specific for Dhx9/NDHII/RHA Reviewed

    Kotani Manato, Harada Akihito, Odawara Jun, Azuma Masayuki, Okada Seiji, Nishiyama Yuko, Nakamura Mako, Tachibana Taro, Ohkawa Yasuyuki

    HYBRIDOMA   29 ( 3 )   259 - 261   2010.06( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2009.0107

  • Rat Monoclonal Antibody Specific for the Chromatin Remodeling Factor, CHD1 Reviewed

    Yoshimura Saori, Harada Akihito, Odawara Jun, Azuma Masayuki, Okada Seiji, Nakamura Mako, Ohkawa Yasuyuki, Tachibana Taro

    HYBRIDOMA   29 ( 3 )   237 - 240   2010.06( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2009.0106

  • Rat Monoclonal Antibody Specific for MyoD Reviewed

    Harada Akihito, Ohkawa Yasuyuki, Ao Shinpei, Odawara Jun, Okada Seiji, Azuma Masayuki, Nishiyama Yuko, Nakamura Mako, Tachibana Taro

    HYBRIDOMA   29 ( 3 )   255 - 258   2010.06( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2009.0117

  • Generation of a Rat Monoclonal Antibody Specific for Chd2 Reviewed

    Harada Akihito, Yoshimura Saori, Odawara Jun, Azuma Masayuki, Okada Seiji, Nakamura Mako, Tachibana Taro, Ohkawa Yasuyuki

    HYBRIDOMA   29 ( 2 )   173 - 177   2010.04( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2009.0090

  • Rat Monoclonal Antibody Specific for Septin 9 Reviewed

    Tachibana Taro, Okazaki Etsuko, Yoshimi Tomohiko, Azuma Masayuki, Kakehashi Anna, Wanibuchi Hideki

    HYBRIDOMA   29 ( 2 )   169 - 171   2010.04( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1089/hyb.2009.0092

  • A Rat Monoclonal Antibody Against the Chromatin Remodeling Factor CHD5 Reviewed

    Yoshimura Saori, Yoshimi Tomohiko, Ohkawa Yasuyuki, Azuma Masayuki, Tachibana Taro

    HYBRIDOMA   29 ( 1 )   63 - 66   2010.02( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2009.0069

  • Production and Characterization of Monoclonal Antibodies to Mouse Germ Cells Reviewed

    yokoyama Chikako, Katoh-Fukui Yuko, Morohashi Ken-ichirou, Konno Daijiro, Azuma Masayuki, Tachibana Taro

    HYBRIDOMA   29 ( 1 )   53 - 57   2010.02( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2009.0101

  • Generation of A Rat Monoclonal Antibody Specific for Glyoxalase I Reviewed

    Nakadate Yusuke, Mizuguchi Chiaki, Azuma Masayuki, Tachibana Taro

    HYBRIDOMA   28 ( 6 )   447 - 450   2009.12( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2009.0048

  • Generation of Rat Monoclonal Antibodies Specific for Ad4BP/SF-1 Reviewed

    Yokoyama Chikako, Komatsu Tomoko, Ogawa Hidesato, Morohashi Ken-ichirou, Azuma Masayuki, Tachibana Taro

    HYBRIDOMA   28 ( 2 )   113 - 119   2009.04( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2008.0084

  • The formation of argpyrimidine, a methylglyoxal-arginine adduct, in the nucleus of neural cells Reviewed

    Nakadate Yusuke, Uchida Koji, Shikata Keiji, Yoshimura Saori, Azuma Masayuki, Hirata Tatsumi, Konishi Hiroyuki, Kiyama Hiroshi, Tachibana Taro

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   378 ( 2 )   209 - 212   2009.01( ISSN:0006-291X

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bbrc.2008.11.028

  • Power Generation Characteristics and Performance Improvement of a Bio-fuel Cell Using Yeast Reviewed

    WAKISAKA Tomoyuki, TAKADA Yogo, AZUMA Masayuki

    High Temperature Society of Japan, Journal of High Temperature Society   35 ( 5 )   283 - 290   2009( ISSN:0387-1096

     More details

    Publishing type:Research paper (scientific journal)  

    Nowadays, bio-fuel cells which utilize the enzymes of microbes are widely noticed. In this study, the authors made a bio-fuel cell which utilized dry yeast along with sucrose as fuel, and conducted experiments under various conditions in order to improve its power generation performance. The kinds and concentrations of the electron mediator and oxidizer solutions and the number of current collectors in the anode and cathode were optimized. As a result, the single bio-fuel cell with six sheets of current collectors (each area was 20 cm<SUP>2</SUP>) in each of the anode and cathode was able to generate the maximum power of about 9 mW. Moreover, the authors measured the performance of the fuel cell using wild yeast and analyzed the variations in the concentrations of reaction substances, and further conducted experiments using reagents affecting the metabolism of yeast in order to examine the electricity generation mechanism in the bio-fuel cell.

    DOI: 10.7791/jhts.35.283

    CiNii Article

  • Generation and characterization of a monoclonal antibody against NPI-1 subfamily of importin alpha Reviewed

    Tachibana Taro, Sakaguchi Naoko, Miyamoto Yoichi, Sekimoto Toshihiro, Yoneda Yoshihiro, Azuma Masayuki

    HYBRIDOMA   27 ( 4 )   285 - 289   2008.08( ISSN:1554-0014

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/hyb.2008.0010

  • Synthesis and degradation of acyl peptide using enzyme from Pseudomonas aeruginosa Reviewed

    Islam Nazneen Naher, Igarashi Koichi, Tachibana Taro, Ooshima Hiroshi, Azuma Masayuki

    社団法人 日本生物工学会 JOURNAL OF BIOSCIENCE AND BIOENGINEERING   105 ( 3 )   282 - 287   2008.03( ISSN:1389-1723

     More details

    Publishing type:Research paper (scientific journal)  

    The detailed properties of the enzyme from <i>Pseudomonas aeruginosa</i>, which catalyzes the <i>N</i>-acyl linkage between myristic acid and the <i>N</i>-terminal glycine residue of the octapeptide GNAAAARR-NH<sub>2</sub> (PKA) in aqueous solution without ATP and CoA, were studied. The substrate specificity for the acyl peptide in the synthetic reaction was examined, and it was found that at least eight amino acid residues are required for the reaction and that the <i>N</i>-terminal glycine residue is not absolutely essential for the reaction because the activity was detected using the octapeptide that has an <i>N</i>-terminal alanine. The activity was also strongly affected by the amino acid sequence because the activity was very weak in the reaction using GARASVLS-NH<sub>2</sub> (HIV-1p17<sup>gag</sup>). The substrate specificity for fatty acids was also examined. In the reactions using lauric acid and decanoic acid, only slight activities were detected; however, those activities were very small compared with the activity in the reaction using myristic acid. In addition, the degradation of myristoyl PKA by the enzyme was detected, although there are only a few reports on demyristoylation. The optimum pH and temperature of the degradation reaction were consistent with those of the synthetic reaction. The degradation reaction was inhibited by divalent cations.<br>

    DOI: 10.1263/jbb.105.282

    CiNii Article

  • Saccharomyces cerevisiae Mutant Displaying β-Glucans on Cell Surface Reviewed

    Sakai Yumiko, Azuma Masayuki, Takada Yuki, UMEYAMA Takashi, KANEKO Aki, FUJITA Tsuyoshi, IGARASHI Koichi, OOSHIMA Hiroshi

    公益社団法人日本生物工学会 Journal of bioscience and bioengineering   103 ( 2 )   161 - 166   2007.02( ISSN:13891723

     More details

    Publishing type:Research paper (scientific journal)  

    The deletion of MCD4 leads to an increase in β-1,6-glucan level and a decrease in glycosylphos-phatidylinositol-anchored protein and mannan levels in the cell wall of Saccharomyces cerevisiae, suggesting that mcd4 deletion mutant(mcd4Δ) displays β-glucans on the cell surface without a mannan cover. An observation of the cell surface of mcd4Δ cells and an examination of the effect of contact between mcd4Δ cells and mouse macrophages indicated that macrophages were activated by contact with mcd4Δ cells displaying β-glucans on the cell surface. We further examined the effect of intraperitoneal ethanol-fixed mcd4Δ cells on the survival period of mice infected with Candida albicans. mcd4Δ cells prolonged the survival period, implying that mcd4Δ cells may enhance the immune function of mice via macrophage activation. Moreover, we examined the structures of β-glucans(i.e., alkali- and acetic acid-insoluble β-glucans) extracted from mcd4Δ with ^<13>C-NMR and the effect of extracted β-glucans on TNF-α secretion from macrophages. The structures of the β-glucans from mcd4Δ differed from those of wild type(WT); however, there was no difference in tumor necrosis factor-α(TNF-α) secretion level between β-glucans from mcd4Δ and those from WT. The yield of purified β-glucans obtained from dry cells of mcd4Δ was higher than that obtained from dry cells of WT. mcd4Δ may be a superior strain for the preparation of β-glucans.

    CiNii Article

  • Flowerlike agglomerates of calcium carbonate crystals formed on an eggshell membrane Reviewed

    Takiguchi Masakazu, Igarashi Koichi, Azuma Masayuki, Ooshima Hiroshi

    CRYSTAL GROWTH & DESIGN   6 ( 12 )   2754 - 2757   2006.12( ISSN:1528-7483

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/cg0604576

  • New Detection Method for Hydrogen Gas for Screening Hydrogen-Producing Microorganisms Using Water-Soluble Wilkinson's Catalyst Derivative Reviewed

    Katsuda Tomohisa, Ooshima Hiroshi, Azuma Masayuki, KATO Jyoji

    公益社団法人日本生物工学会 Journal of bioscience and bioengineering   102 ( 3 )   220 - 226   2006.09( ISSN:13891723

     More details

    Publishing type:Research paper (scientific journal)  

    A water-soluble color indicator was developed for the effective screening of hydrogen-producing microorganisms. This indicator consists of a coloring agent and a water-soluble derivative of Wilkinson's catalyst. Wilkinson's catalyst, Tris(triphenylphosphine) rhodium chloride, had been developed as a catalyst for the hydrogenation of olefins. We used a sulfonate of the catalyst for the hydrogenation of coloring agent in an aqueous medium. Several coloring agents, such as methyl orange, methyl red sodium, neutral red and Evan's blue, dissolved in water together with the sulfonated catalyst showed a change in color when hydrogen gas was fed into the solution by sparging at room temperature. We confirmed that methyl orange was decolorized by biologically produced hydrogen, when the photosynthetic bacterial strain Rhodobacter capsulatus ST-410 was grown in a medium containing 0.6mM catalyst and 0.075mM methyl orange in test tubes of 5ml working volume.

    CiNii Article

  • Purification and characterization of enzyme responsible for N-myristoylation of octapeptide in aqueous solution without ATP and coenzyme A from Pseudomonas aeruginosa Reviewed

    Jyomoto Takahiro, Azuma Masayuki, Islam Nazneen Naher, Fujinami Ryo, Takao Toshifumi, Ogawa Takayuki, Tabuchi Masaki, Igarashi Koichi, Kato Jyoji, Ooshima Hiroshi

    社団法人 日本生物工学会 JOURNAL OF BIOSCIENCE AND BIOENGINEERING   102 ( 3 )   193 - 197   2006.09( ISSN:1389-1723

     More details

    Publishing type:Research paper (scientific journal)  

    The enzyme that catalyzes <i>N</i>-acyl linkage between myristic acid and the NH<sub>2</sub>-terminal glycine residue of the octapeptide Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg-NH<sub>2</sub> in aqueous solution without ATP and coenzyme A was found in <i>Pseudomonas aeruginosa</i>. The enzyme was purified from cell-free crude extract using DEAE-Cellulose, Sephadex G-200, CM-Sephadex C-50, and hydroxyapatite column chromatographies, and then purified approximately 1900-fold with about 1.5% recovery of enzyme activity from the crude extract. Finally, the purified enzyme showed a main band on SDS polyacrylamide gel electrophoresis after staining with Coomassie Brilliant Blue. The band corresponded to a molecular mass of approximately 60 kDa. The <i>K</i><sub>m</sub>s of the purified enzyme for the substrate myristic acid and the octapeptide were 0.36 and 2.6 mM, respectively. When myristoyl-CoA instead of myristic acid was used as the substrate for the enzyme reaction, myristoyl octapeptide could be synthesized as observed in the case of myristic acid. The <i>K</i><sub>m</sub> of myristoyl-CoA was 0.17 mM.<br>

    DOI: 10.1263/jbb.102.193

    CiNii Article

  • Tubular structure agglomerates of calcium carbonate crystals formed on a cation-exchange membrane Reviewed

    Takiguchi M, Igarashi K, Azuma M, Ooshima H

    CRYSTAL GROWTH & DESIGN   6 ( 7 )   1611 - 1614   2006.07( ISSN:1528-7483

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/cg060045x

  • Relationship between Cell Morphology and Intracellular Potassium Concentration in Candida albicans Reviewed

    WATANABE Hiroshi, AZUMA Masayuki, IGARASHI Koichi, OOSHIMA Hiroshi

    Journal of antibiotics = An International Journal Devoted to Research on Bioactive Microbial Products   59 ( 5 )   281 - 287   2006.05( ISSN:00218820

     More details

    Publishing type:Research paper (scientific journal)  

    CiNii Article

  • Deletion of the CaBIG1 gene reduces beta-1,6-glucan synthesis, filamentation, adhesion, and virulence in Candida albicans Reviewed

    Umeyama T, Kaneko A, Watanabe H, Hirai A, Uehara Y, Niimi M, Azuma M

    INFECTION AND IMMUNITY   74 ( 4 )   2373 - 2381   2006.04( ISSN:0019-9567

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1128/IAI.74.4.2373-2381.2006

  • Valinomycin Affects the Morphology of Candida albicans Reviewed

    WATANABE Hiroshi, AZUMA Masayuki, IGARASHI Koichi, OOSHIMA Hiroshi

    Journal of antibiotics = An International Journal Devoted to Research on Bioactive Microbial Products   58 ( 12 )   753 - 758   2005.12( ISSN:00218820

     More details

    Publishing type:Research paper (scientific journal)  

    CiNii Article

  • Manipulation of morphological transition in Saccharomyces cerevisiae mutant J19 Reviewed

    Maneesri J, Azuma M, Igarashi K, Sugihara A, Ooshima H

    BIOCHEMICAL ENGINEERING JOURNAL   27 ( 1 )   72 - 76   2005.12( ISSN:1369-703X

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bej.2005.07.001

  • Analysis of chitin at the hyphal tip of Candida albicans using calcofluor white Reviewed

    Watanabe H, Azuma M, Igarashi K, Ooshima H

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   69 ( 9 )   1798 - 1801   2005.09( ISSN:0916-8451

     More details

    Publishing type:Research paper (scientific journal)  

  • Deletion of MCD4 involved in glycosylphosphatidylinositol (GPI) anchor synthesis leads to an increase in beta-1,6-glucan level and a decrease in GPI-anchored protein and mannan levels in the cell wall of Saccharomyces cerevisiae Reviewed

    Maneesri J, Azuma M, Sakai Y, Igarashi K, Matsumoto T, Fukuda H, Kondo A, Ooshima H

    社団法人 日本生物工学会 JOURNAL OF BIOSCIENCE AND BIOENGINEERING   99 ( 4 )   354 - 360   2005.04( ISSN:1389-1723

     More details

    Publishing type:Research paper (scientific journal)  

    Most proteins involved in the synthesis of the GPI core structure of Saccharomyces cerevisiae are essential for growth. To explore the relationship between the GPI anchor structure and β-1,6-glucan synthesis, we screened deletion mutants in genes involved in GPI synthesis for osmotic remedial growth. Heterozygous diploid strains were dissected on medium with osmotic support and slow growth of the mcd4 deletion mutant was observed. The mcd4 mutant showed abnormal morphology and cell aggregation, and was hypersensitive to SDS, hygromycin B and K1 killer toxin. Incorporation of GPI cell wall proteins was examined using a GPI-Flo1 fusion protein. The result suggested that the mcd4 deletion causes a decrease in GPI cell wall proteins levels. The mutation also caused a decrease in mannan levels and an increase in alkali-insoluble β-1,6-glucan and chitin levels in the cell wall.

    DOI: 10.1263/jbb.99.354

    CiNii Article

  • Rot1p of Saccharomyces cerevisiae is a putative membrane protein required for normal levels of the cell wall β-1,6-glucan. Reviewed

    Machi, K., Azuma M., Igarashi, K., Matsumoto, T., Fukuda, H., Kondo, A. and Ooshima, H.

    Microbiology   150   3163 - 3173   2004

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • 酵母培養に用いる培地中のグルコース濃度の計測. Reviewed

    原誠一, 岸本友和, 村治雅文, 辻本浩章, 東雅之, 大嶋寛

    IEEJ Trans. SM   124   49 - 53   2004

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer Toxin.

    Genetics   163   875 - 894   2003

     More details

    Publishing type:Research paper (scientific journal)  

  • Characterization of a Saccharomyces cerevisiae Mutant with Pseudohyphae and Cloning of a Gene Complementing the Mutation. Reviewed

    Jaruwan Maneesri, Masayuki Azuma, Satoshi Torii, Koichi Igarashi, and Hiroshi Ooshima.

    Biosci. Biotech. Biochem.   67   517 - 524   2003

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Effects of a Solute Analogue p-Acetoacetanisidide on the Crystallization of p-Acetanisidide. Reviewed

    Akira Saito, Koichi Igarashi, Masayuki Azuma and Hiroshi Ooshima.

    Journal of Chemical Engineering of Japan   36   953 - 958   2003

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Control of Polymorphs on the Crystallization of Glycine Using WWDJ Batch Crystallizer Reviewed

    K. IGARASHI, Y. SASAKI, M. AZUMA, H. NODA and H. OOSHIMA.

    Eng. Life Sci.   3   159 - 163   2003

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Saccharomyces cerevisiae Big1p, a putative endoplasmic reticulum membrane protein required for normal levels of cell wall beta-1,6-glucan.

    yeast   19   783 - 793   2002

     More details

    Publishing type:Research paper (scientific journal)  

  • Aggregation of p-Acetaniside Molecules in the Under- and Super-saturated Solution and its Effect on Crystalization. Reviewed

    Akira Saito, Koichi Igarashi, Masayuki Azuma and Hiroshi Ooshima.

    Journal of Chemical Engineering of Japan   35   1133 - 1139   2002

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Single Work  

  • Removal of Cadmium ion by the Moss Pohlia flexuosa. M. Azuma, A. Obayashi, M. Kondoh, C. Kawasaki, K. Igarashi, J. Kato, H. Ooshima

    the Book Series on Progress in Biotechnology   16   175 - 180   2000

     More details

    Publishing type:Research paper (scientific journal)  

  • Microbial Growth Regulation Using Photoresponsive Siderophore. T. Masuda, M. Azuma, H. Ooshima, S. Tamagaki, T. Nagasaki

    Chemistry Letters   872 - 873   2000

     More details

    Publishing type:Research paper (scientific journal)  

  • Light Intensity Distribution in the Externally Illuminated Cylindrical Photobioreacter and Its Application for the Hydrogen Production by Rhodobacter capsulatus. T. Katsuda, T. Arimoto, K. Igarashi, M. Azuma, J. Kato, S. Takakuwa, H. Ooshima

    Biochem. Eng. J.   5   157 - 164   2000

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Single Work  

  • Increase in xylitol production by Candida tropicalis upon addition of salt . M. Azuma, T. Ikeuchi, R. Kiritani, J. Kato, H, Ooshima

    Biomass Bioenerg.   19   129 - 136   2000

     More details

    Publishing type:Research paper (scientific journal)  

  • Effect of D-glucose on induction of xylose reductase and xylitol dehydrogenase in Candida tropicalis in the presence of NaCl. T. Ikeuchi, R. Kiritani, M. Azuma, H.Ooshima

    Journal of Basic Microbiology   40   167 - 175   2000

     More details

    Publishing type:Research paper (scientific journal)  

  • Effect of Ethanolamine as a Nitrogen Source on Hydrogen Production by Rhodobacter capsulatus. T. Katsuda, M. Azuma, J. Kato, S. Takakuwa, H. Ooshima

    Biosci. Biotechnol. Biochem.   64   243 - 253   2000

     More details

    Publishing type:Research paper (scientific journal)  

  • Cell Extensions in pkc1 Mutants of Saccharomyces cerevisiae Reviewed

    M. Azuma, S. Torii, J. Kato, and H. Ooshima

    Can. J. Microbiol.   45   38 - 44   1999

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • The initial stage of crystallization of lysozyme: a differential scanning calorimetric (DSC) study. Reviewed

    K. Igarashi, M. Azuma, J. Kato, and H. Ooshima

    J. Crystal Growth   204   191 - 200   1999

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Screening of Microorganisms for Xylitol Production and Fermentation Behavior in High Concentration of Xylose. Reviewed

    T. Ikeuchi, M. Azuma、J. Kato, and H. Ooshima

    Biomass Bioenerg.   16   333 - 339   1999

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Removal of Mercury Ion by the Moss Pohlia flexuosa. Reviewed

    M. Kondoh, M. Fukuda, M. Azuma, H. Ooshima, and J. Kato.

    J. Ferment. Bioeng.   86   197 - 201   1998

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Design of a Spray Cycle Bioreactor and its Application for Riboflavin Production Reviewed

    H. Ooshima, Y. Yamane, Y. Nakamura, H. Sakashita, M. Azuma, and J. Kato.

    Appl. Biochem. Biotech.   73   51 - 58   1998

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Production of Hydrogen by a Hydrogenase-Deficient Mutant of Rhodobacter capsulatus. Reviewed

    H. Ooshima, S. Takakuwa, T. Katsuda, M. Okuda, T. Shirasawa, M. Azuma, and J. Kato.

    J. Ferment. Bioeng.   85   470 - 475   1998

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Evaluation of Spray Cycle Bioreactor Using L-Alanine Degradation by Candida maltosa. Reviewed

    H. Sakashita, M. Azuma, H. Ooshima, and J. Kato.

    Biosci. Biotech. Biochem.   62   1664 - 1667   1998

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Acyl Amino Acid Derivatives as Novel Inhibitiors of Influenza Neuraminidase Reviewed

    M. Kondoh, T. Furutani, M. Azuma, H. Ooshima, and J. Kato.

    Biosci. Biotech. Biochem.   61   870 - 874   1997

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • INHIBITION OF OCTAPEPTIDE N- MYRISTOYLATION BY ACYL AMINO ACIDS AND ACYL ALKANOLAMINES. Reviewed

    M. Tabuchi, H. Okamoto, T. Furutani, M. Azuma, H. Ooshima, T. Otake, T. Kawahata, and J. Kato.

    J. Enzyme Inhibit.   12   27 - 36   1997

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Mechanism of Crystal Growth of Protein: Differential Scanning Calorimetry of Thermolysin Crystal Suspension. Reviewed

    H. Ooshima, S. Urabe, K. Igarashi, M. Azuma, and J. Kato.

    ACS SYMPOSIUM SERIES   667   18 - 27   1997

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • 芝草雪腐病ー特に黒色小粒菌核病に関する研究ー  第3報 雪腐黒色小粒菌核病菌に対する拮抗細菌が生産するフェナジン-1-カルボン酸の作用. Reviewed

    大志万浩一, 東雅之, 重光春洋, 久能均.

    芝草研究   24   129 - 138   1996

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Basidifferqinone Analogues, Basidifferquinone B and C, Which Induce Fruiting-body Formation of a Basidiomycete, Favolus arcularius Reviewed

    M. Azuma, M. Yoshida, S. Horinouchi, and T. Beppu.

    Biosci. Biotech. Biochem.   57   344 - 345   1993

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Basidifferquinone, a New Inducer for Fruiting-body Formation of a Basidiomycetes Favolus arcularius from a Streptomyces strain II. Structure of Basidifferquinone Reviewed

    M. Azuma, K. Hori, Y. O-hashi, M. Yoshida, S. Horinouchi, and T. Beppu

    Agric. Biol. Chem.   54   1447 - 1452   1990

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • RIBONUCLEASES CATALYZE THE SYNTHESIS OF B-FACTOR (3'-BUTYLPHOSPHORYL AMP), AN INDUCER OF RIFAMYCIN PRODUCTION IN A NOCARDIA SP. Reviewed

    M. Azuma, K. Nishi, S. Horinouchi, and T. Beppu.

    J. Antibiot.   43   321 - 323   1990

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Basidifferquinone, a New Inducer for Fruiting-body Formation of a Basidiomycetes Favolus arcularius from a Streptomyces strain I. Screening and Isolation. Reviewed

    M. Azuma, M. Yoshida, S. Horinouchi, and T. Beppu.

    Agric. Biol. Chem.   54   1441 - 1446   1990

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • EFFECT OF B-FACTOR AND ITS ANALOGUES ON RIFAMYCIN BIOSYNTHESIS IN NOCARDIA SP. Reviewed

    T. Kawaguchi, M. Azuma, S. Horinouchi, and T. Beppu

    J. Antibiot.   41   360 - 365   1988

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Escherichia coli H+-ATPase. Reviewed

    T. Noumi, M. Azuma, S. Shimomura, M. Maeda, and M. Futai

    J. Biol. Chem.   262   14798 - 14982   1987

     More details

    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

▼display all

Books and Other Publications

  • バイオプロセスを用いた有用性物質生産技術~動物・植物細胞や微生物の培養・分離精製技術~

    尾島由紘 東雅之( Role: Contributor ,  11)

    技術情報協会  2022.11 

  • 微生物を用いた発電および水素生産, 中枢代謝経路を改変した大腸菌を触媒として用いた微生物燃料電池

    東 雅之,尾島 由紘( Role: Joint author)

    シーエムシー出版  2021.11 

     More details

    Responsible for pages:39-46  

  • Catalyst Development of Microbial Fuel Cells for Renewable-Energy Production

    M. Azuma, Y. Ojima( Role: Joint author)

    Current Topics in Biochemical Engineering (Book), IntechOpen  2018.11 

     More details

    Responsible for pages:19   Book type:Scholarly book Participation form:First Author

  • 微生物電池による廃水処理システム最前線. 渡邊一哉監修 第1編 2-1「微生物燃料電池向け酵母の開発」

    東雅之 他( Role: Contributor)

    NTS出版  2013 

     More details

    Responsible for pages:66-74  

  • ナノ機能性分子の利用に適した反応場の構築とその安定化

    東雅之 他( Role: Contributor)

    ナノバイオテクノロジーの最前線(シーエムシー出版)  2003 

     More details

    Responsible for pages:53-59  

  • バイオ触媒

    東雅之 他( Role: Contributor)

    化学便覧 応用化学6版 (丸善)  2002 

     More details

    Responsible for pages:285-286  

▼display all

MISC

  • パン酵母細胞壁に含まれる糖タンパク質の乳化作用 Invited International journal

    東 雅之,尾島 由紘

    月刊ファインケミカル   51 ( 10 )   48 - 54   2022.10

     More details

    Authorship:Lead author, Corresponding author   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   International / domestic magazine:Domestic journal  

  • 大腸菌の外膜小胞高生産株の作製とタンパク質分泌生産等への利用 Invited

    尾島 由紘,東 雅之

    酵素工学ニュース   86   32 - 35   2021.10

     More details

    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Joint Work  

  • 外膜小胞に着目した大腸菌のタンパク質分泌生産の試み Invited

    尾島 由紘、 東 雅之

    化学工業   72 ( 5 )   319 - 324   2021.05

     More details

    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Joint Work  

  • パン酵母由来の乳化能を有する糖タンパク質の解析 Invited Reviewed

    東 雅之、尾島 由紘

    科学と工業   94 ( 12 )   362 - 369   2020.12

     More details

    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Joint Work  

  • 細胞から電子を奪う微生物燃料電池に適した触媒の開発

    東雅之

    化学工学会 Newsletter   39   11 - 14   2015

     More details

    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Single Work  

  • 微生物を触媒にしたバイオ燃料電池 — 生命が生み出す電気エネルギー

    東雅之

    生産と技術(生産技術振興協会)   65 ( 4 )   81 - 83   2013

     More details

    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Single Work  

▼display all

Presentations

  • 酵母細胞壁タンパク質による乳化現象の抗真菌物質スクリーニングへの応用 Domestic conference

    根路銘 伸介,都築 舞,二塚 美紀,髙田 真穂,横田 直紀,尾島 由紘,東 雅之

    化学工学会第88年会  2023.03 

     More details

    Presentation type:Poster presentation  

    Venue:東京  

  • 外膜タンパク質OmpWに着目した大腸菌の表層ディスプレイの検討 Domestic conference

    尾島 由紘,西田 行希,澤邊 朋美,東 雅之

    化学工学会第88年会  2023.03 

     More details

    Presentation type:Oral presentation (general)  

    Venue:東京  

  • パン酵母を活用した金属吸着剤の開発 Invited Domestic conference

    東雅之

    京阪神スタートアップアカデミア・コアリション(KSAC) フォローアップデモデイ【NEXT PIONEER 2022】  2023.02 

     More details

    Presentation type:Oral presentation (general)  

    Venue:京都  

  • パン酵母を活用した低環境負荷型金属吸着剤の開発 Invited Domestic conference

    東 雅之

    大阪公立大学イノベーションアカデミーワークショップ   2023.01 

     More details

    Presentation type:Oral presentation (general)  

    Venue:大阪  

  • 大腸菌の外膜小胞を介した有用物質分泌生産の検討 Domestic conference

    熊添 優希,澤邊 朋美,尾島 由紘,東 雅之

    化学工学会 岡山大会2022  2022.12 

     More details

    Presentation type:Oral presentation (general)  

    Venue:岡山  

  • 細胞表面をカチオン化した化学修飾酵母による水溶液中からのセレン酸の除去 Domestic conference

    舟橋 美希,濱 理奈,錦織 弘宜,尾島 由紘,東 雅之

    化学工学会 岡山大会2022  2022.12 

     More details

    Presentation type:Oral presentation (general)  

    Venue:岡山  

  • 効率的な油脂回収を目的としたRhodotorula toruloides細胞壁変異株の取得 Domestic conference

    市村 仁,尾島 由紘,東 雅之

    化学工学会 岡山大会2022  2022.12 

     More details

    Presentation type:Oral presentation (general)  

    Venue:岡山  

  • Recovery of metal ions and mineralization by biosorption onto phosphorylated dry baker’s yeast Invited International conference

    Yoshihiro Ojima, Maya Kihara, Masayuki Azuma

    The 34th Annual Meeting of the Thai Society for Biotechnology and International Conference  2022.11 

     More details

    Presentation type:Oral presentation (invited, special)  

    Venue:Bangkok, Thailand  

  • Outer membrane vesicles of Escherichia coli and its application to the biotechnology field, Invited International conference

    Yoshihiro Ojima, Tomomi Sawabe, Masayuki Azuma

    The 34th Annual Meeting of the Thai Society for Biotechnology and International Conference  2022.11 

     More details

    Presentation type:Oral presentation (invited, special)  

  • 大腸菌の外膜タンパク質OmpWを利用した表層ディスプレイ法の開発 Domestic conference

    西田 行希,尾島 由紘,東 雅之

    第74回日本生物工学会大会  2022.10 

     More details

    Presentation type:Oral presentation (general)  

    Venue:大阪  

  • 酵母の多層化した細胞壁の解析とその形成メカニズムについて Domestic conference

    細田 景太,尾島 由紘,田原 悠平,宮田 真人,東 雅之

    第74回日本生物工学会大会  2022.10 

     More details

    Presentation type:Oral presentation (general)  

    Venue:大阪  

  • 酵母由来Gasタンパク質の乳化能と糖鎖構造の関係 Domestic conference

    二塚 美紀,髙田 真穂,尾島 由紘,東 雅之

    第74回日本生物工学会大会  2022.10 

     More details

    Presentation type:Oral presentation (general)  

    Venue:大阪  

  • リン高蓄積酵母のリン含有量や貯蔵形態に関する解析 Domestic conference

    尾島由紘,直井 喬平,東雅之

    第74回日本生物工学会大会  2022.10 

     More details

    Presentation type:Oral presentation (general)  

    Venue:大阪  

  • パン酵母活用金属吸着剤の開発 Invited Domestic conference

    東 雅之

    京阪神スタートアップアカデミア・コアリション(KSAC)デモデイ  2022.02 

     More details

    Presentation type:Oral presentation (general)  

    Venue:on line  

  • Aberrant membrane structures in hypervesiculating Escherichia coli strain ΔmlaEΔnlpI visualized by quick-freeze deep-etch electron microscopy Domestic conference

    Yoshihiro Ojima, Tomomi Sawabe, Mao Nakagawa, Yuhei O. Tahara, Makoto Miyata, Masayuki Azuma

    EMBO Biologists Workshop Bacterial membrane vesicles: Biogenesis, functions and medical applications (Hyprid),  2021.11 

     More details

    Presentation type:Poster presentation  

  • 土壌より単離したBacillus licheniformis RK14株の自発的な凝集体形成 Domestic conference

    俣野沙月,尾島由紘,東雅之

    第73回日本生物工学会大会, オンライン  2021.10 

     More details

    Presentation type:Oral presentation (general)  

  • 高いβ-グルカン生産能を持つAureobasidium pullulansの細胞壁構造の解析 Domestic conference

    谷本悟,尾島由紘,鈴木利雄,東雅之

    第73回日本生物工学会大会, オンライン  2021.10 

     More details

    Presentation type:Oral presentation (general)  

  • 乳化およびマクロファージ活性化能を有する酵母由来Gas1タンパク質の構造と機能 Domestic conference

    髙田真穂,二塚美紀,尾島由紘,東雅之

    第73回日本生物工学会大会, オンライン  2021.10 

     More details

    Presentation type:Oral presentation (general)  

  • ヌクレオシド系抗生物質トヨカマイシンのCandida albicansに対する作用の検討 Domestic conference

    横田直紀,谷畑友基,尾島由紘,東雅之

    第73回日本生物工学会大会, オンライン  2021.10 

     More details

    Presentation type:Oral presentation (general)  

  • 電子顕微鏡により可視化された大腸菌の外膜小胞高生産株ΔmlaEΔnlpIの異常な膜構造 Domestic conference

    尾島由紘,澤邊朋美,中川真緒,田原悠平,宮田真人,東雅之

    第73回日本生物工学会大会, オンライン  2021.10 

     More details

    Presentation type:Oral presentation (general)  

  • 大腸菌Nissle1917株の外膜小胞高生産株の特性解析 Domestic conference

    中川真緒,尾島由紘,澤邊朋美,田原悠平,宮田真人,東雅之

    第73回日本生物工学会大会, オンライン  2021.10 

     More details

    Presentation type:Oral presentation (general)  

  • ポリ-γ-グルタミン酸とキトサンを用いた微生物凝集法の開発とその利用 Domestic conference

    土井健生,Parra Gabriel,尾島由紘,東雅之

    第73回日本生物工学会大会, オンライン  2021.10 

     More details

    Presentation type:Oral presentation (general)  

  • 遺伝子改変による大腸菌燃料電池の出力改善と細胞からメディエーターへの電子供与の簡易評価 Domestic conference

    河野雄司、菊池亮太、駒大輔、大本貴士、尾島由紘、東雅之

    化学工学会第52回秋季大会(オンライン)  2021.09 

     More details

    Presentation type:Poster presentation  

  • リン蓄積酵母の特性解析と金属回収への応用 Domestic conference

    直井喬平、尾島由紘、東雅之

    化学工学会第52回秋季大会(オンライン)  2021.09 

     More details

    Presentation type:Poster presentation  

  • 大腸菌 Nissle1917 株の外膜小胞高生産株の構築 Domestic conference

    中川 真緒、尾島 由紘、澤邉 朋美、田原 悠平、宮田 真人、東 雅之

    日本生物工学会関西支部 2020年度学生オンライン発表会  2020.12 

     More details

    Presentation type:Oral presentation (general)  

  • トヨカマイシンの Candida albicans に対する作用の検討 Domestic conference

    横田 直紀、谷畑 友基、尾島 由紘、東 雅之

    日本生物工学会関西支部 2020年度学生オンライン発表会  2020.12 

     More details

    Presentation type:Oral presentation (general)  

  • 酵母の最外層を構成するマンナンタンパク質が高分子化合物の透過に与える影響 Domestic conference

    大良 優依、尾島 由紘、東 雅之

    日本生物工学会関西支部 2020年度学生オンライン発表会  2020.12 

     More details

    Presentation type:Oral presentation (general)  

  • 大腸菌フロックの複合微生物化の検討 Domestic conference

    俣野 沙月、大塚 朱音、本間 裕章、尾島 由紘、東 雅之

    日本生物工学会関西支部 2020年度学生オンライン発表会  2020.12 

     More details

    Presentation type:Oral presentation (general)  

  • 大腸菌の外膜小胞高生産株の生産促進機構 Invited Domestic conference

    尾島 由紘、東雅之

    生物工学Webシンポジウム2020(日本生物工学会)  2020.09 

     More details

    Presentation type:Oral presentation (general)  

  • ダウンストリームプロセスを効率化する酵母変異株の構築 Domestic conference

    奥村一仁, 尾島由紘, 東雅之

    化学工学会姫路大会2019  2019.12 

     More details

    Presentation type:Oral presentation (general)  

  • リン酸基修飾酵母を活用した低環境負荷型有価金属回収システムの創出 Invited Domestic conference

    東 雅之

    関西スマートセルフォーラム2019第2回セミナー  2019.12 

     More details

    Presentation type:Oral presentation (invited, special)  

  • Outer membrane vesicles of Gram-negative bacteria and its application to microbial biotechnology Invited International conference

    Yoshihiro Ojima, Masayuki Azuma

    ICGEB-IMBT Workshop2019  2019.11 

     More details

    Presentation type:Oral presentation (general)  

  • 大腸菌外膜小胞の分泌促進メカニズムの解析 Domestic conference

    澤邊朋美、尾島由紘、田原悠平、宮田真人、東雅之

    膜シンポジウム2019  2019.11 

     More details

    Presentation type:Poster presentation  

  • 乳化を引き起こす酵母細胞表層タンパク質の同定と解析 Domestic conference

    上田茉奈, 齋藤大輝, 尾島由紘, 東雅之

    膜シンポジウム2019  2019.11 

     More details

    Presentation type:Poster presentation  

  • 外膜小胞に誘発される大腸菌フロックのグリセロールによる形成促進機構の解析 Domestic conference

    本間裕章, 尾島由紘, 東雅之

    膜シンポジウム2019  2019.11 

     More details

    Presentation type:Poster presentation  

  • Efficient formation of Escherichia coli flocs by glycerol addition International conference

    Hiroaki Honma, Mio Otsuka, Yoshihiro Ojima, Masayuki Azuma

    18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019), PL329, Sapporo, Hokkaido  2019.09 

     More details

    Presentation type:Poster presentation  

  • Identification and analyses of cell surface proteins involved in emulsification and macrophage activation from Saccharomyces cerevisiae International conference

    Mana Ueda, Daiki Saito, Yoshihiro Ojima, Masayuki Azuma

    18th Asian Pacific Confederation of Chemical Engineering Congress (APCChE 2019), PL328, Sapporo, Hokkaido  2019.09 

     More details

    Presentation type:Poster presentation  

  • Rhodotorula mucilaginosaが形成するバイオフィルムを用いた水溶液からの金属回収 Domestic conference

    菅道哉, 尾島由紘, 東雅之

    第71回日本生物工学会大会, 3Ja11, 大阪  2019.09 

     More details

    Presentation type:Oral presentation (general)  

  • リン酸基修飾酵母による鉱物化誘導の解析 Domestic conference

    吉田真実, 木原摩耶, 尾島由紘, 五十嵐幸一, 吉田朋子, 東雅之

    第71回日本生物工学会大会, 3Ja10, 大阪  2019.09 

     More details

    Presentation type:Oral presentation (general)  

  • 大腸菌のnlpI遺伝子が外膜小胞の生産量および特性に与える影響 Domestic conference

    尾島由紘, 児波克哉, 澤邊朋美, 東雅之

    第71回日本生物工学会大会, 2Ip08, 大阪  2019.09 

     More details

    Presentation type:Oral presentation (general)  

  • 種々の固体表面上における家電単離菌のバイオフィルム形成の評価 Domestic conference

    山本克哉, 尾島由紘, 下野雅仁, 多久島朗, 東雅之

    第71回日本生物工学会大会, 1Cp13, 大阪  2019.09 

     More details

    Presentation type:Oral presentation (general)  

  • Promoted secretory protein production by constructing hyper-vesiculation strains of Escherichia coli International conference

    Tomomi Sawabe, Katsuya Konami, Yoshihiro Ojima, Masayuki Azuma

    The 14th Asian Congress on Biotechnology (ACB2019), P2-122, Tamsui, Taiwan  2019.07 

     More details

    Presentation type:Poster presentation  

  • Construction of superior catalyst suitable for microbial fuel cell and effect of anode composition on power of the fuel cell International conference

    Ryota Kikuchi, Taichi Kawaguchi, Daisuke Koma, Takashi Omoto, Yoshihiro Ojima,Masayuki Azuma

    The 14th Asian Congress on Biotechnology (ACB2019), P2-143, Tamsui, Taiwan  2019.07 

     More details

    Presentation type:Poster presentation  

  • Increased poly-γ-glutamic acid production by disruption of ggt gene in Bacillus licheniformis RK14-46 strain and its application for flocculation of real sewage sludge International conference

    Yoshihiro Ojima,Joji Kobayashi,Masayuki Azuma

    The 14th Asian Congress on Biotechnology (ACB2019), S17-04, Tamsui, Taiwan  2019.07 

     More details

    Presentation type:Oral presentation (general)  

  • 伝統技術と最先端バイオ技術の融合により変貌する発酵産業 Invited Domestic conference

    東 雅之

    大阪市立大学公開講座  2019.02 

     More details

    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • 大腸菌外膜小胞を介したIFNの分泌生産 Domestic conference

    児波克哉, 澤邊朋美, 尾島由紘, 東雅之

    膜シンポジウム2018  2018.11 

     More details

    Presentation type:Poster presentation  

  • 微生物の外膜小胞の分泌と凝集体形成の関連性 Domestic conference

    尾島由紘, 東雅之

    膜シンポジウム2018  2018.11 

     More details

    Presentation type:Oral presentation (general)  

  • 木質系バイオマスを燃料にした微生物発電 Domestic conference

    東雅之, 五十嵐幸一, 尾島由紘

    イノベーション・ジャパン2018 (大学組織展示)  2018.08 

     More details

    Presentation type:Symposium, workshop panel (nominated)  

  • 種々の遺伝子改変の組み合わせが微生物燃料電池の出力に与える影響 Domestic conference

    川口太一, 菊池亮太, 駒大輔, 大本貴士,  尾島由紘, 東雅之

    日本生物工学会大会講演要旨集  2018.08 

     More details

    Presentation type:Oral presentation (general)  

  • 培地成分が大腸菌フロック形成に与える影響 Domestic conference

    本間裕章, 大塚未音, 尾島由紘, 東雅之

    日本生物工学会大会講演要旨集  2018.08 

     More details

    Presentation type:Oral presentation (general)  

  • 自然界からの希土類元素分離を可能とするリン酸基修飾酵母の開発 Domestic conference

    木原摩耶, 奥村一仁, 尾島由紘, 東雅之

    日本生物工学会大会講演要旨集  2018.08 

     More details

    Presentation type:Oral presentation (general)  

  • 高い汚泥凝集能を持つポリグルタミン酸の生産性改善に向けた菌株育種と培養工学的な検討 Domestic conference

    小林 誠治, 劉 涛, 尾島 由紘, 東 雅之

    日本生物工学会大会講演要旨集  2018.08  (公社)日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

  • 大腸菌の細胞表層改変による外膜小胞大量分泌株の構築 Domestic conference

    澤邊 朋美, 児波 克哉, 尾島 由紘, 東 雅之

    日本生物工学会大会講演要旨集  2018.08  (公社)日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

  • 乳化を指標とした細胞壁に作用する抗真菌性化合物の探索 Domestic conference

    谷畑 友基, 根路銘 伸介, 尾島 由紘, 東 雅之

    日本生物工学会大会講演要旨集  2018.08  (公社)日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

  • Saccharomyces cerevisiae由来の乳化およびマクロファージ活性化に関与する細胞表層タンパク質の同定と解析 Domestic conference

    上田 茉奈, 齋藤 大輝, 尾島 由紘, 東 雅之

    日本生物工学会大会講演要旨集  2018.08  (公社)日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

  • Development of secretory protein expression system focusing on outer membrane vesicles of Escherichia coli International conference

    Yoshihiro Ojima, Katsuya Konami, Masayuki Azuma

    The 23th Symposium of Young Asian Biological Engineers’ Community(YABEC2017),PC11, Xi’an, China  2017.10 

     More details

    Presentation type:Poster presentation  

  • 乳化能とマクロファージ活性化能を併せ持つ酵母細胞表層成分 Domestic conference

    東雅之

    健康・医療新技術説明会(JST主催), 東京  2017.10 

     More details

    Presentation type:Symposium, workshop panel (nominated)  

  • 微生物の外膜小胞に着目したバイオプロセスの革新 Domestic conference

    尾島 由紘,東 雅之

    化学工学会第49回秋季大会, 名古屋  2017.09 

     More details

    Presentation type:Poster presentation  

  • リン酸基修飾酵母による金属吸着機構の解明と廃液処理への応用 Domestic conference

    木原 摩耶,尾島 由紘,東 雅之

    化学工学会第49回秋季大会, 名古屋  2017.09 

     More details

    Presentation type:Poster presentation  

  • 大腸菌の外膜小胞を介したタンパク質分泌発現系の構築 Domestic conference

    児波 克哉,尾島 由紘,東 雅之

    化学工学会第49回秋季大会, 名古屋  2017.09 

     More details

    Presentation type:Poster presentation  

  • 大腸菌の自発的なフロック形成と有害物分解への応用 Domestic conference

    大塚 未音,尾島 由紘,東 雅之

    日本生物工学会大会平成29年度大会,東京  2017.09 

     More details

    Presentation type:Poster presentation  

  • 大腸菌の代謝や細胞表層電子伝達系の改変が微生物燃料電池の性能に与える影響 Domestic conference

    川口 太一, 福井 早紀, 駒 大輔, 大本 貴士, 尾島 由紘, 東 雅之

    日本生物工学会大会平成29年度大会,東京  2017.09 

     More details

    Presentation type:Symposium, workshop panel (nominated)  

  • 酵母Saccharomyces cerevisiae由来の乳化およびマクロファージ活性化に関与する物質の解析 Domestic conference

    齋藤 大輝, 大西 将也, 尾島 由紘, 東 雅之

    日本生物工学会平成29年度大会, 東京  2017.09 

     More details

    Presentation type:Poster presentation  

  • β-1,3-グルカン合成阻害剤処理によりCandida albicansから遊離する乳化物質の解析 Domestic conference

    根路銘 伸介, 尾島 由紘, 東 雅之

    日本生物工学会平成29年度大会, 東京  2017.09 

     More details

    Presentation type:Poster presentation  

  • 酵母Saccharomyces cerevisiae由来の乳化およびマクロファージ活性化に関与する物質の解析 Domestic conference

    齋藤 大輝, 大西 将也, 尾島 由紘, 東 雅之

    日本生物工学会大会講演要旨集  2017.08  (公社)日本生物工学会

     More details

    Presentation type:Poster presentation  

  • β-1,3-グルカン合成阻害剤処理によりCandida albicansから遊離する乳化物質の解析 Domestic conference

    根路銘 伸介, 尾島 由紘, 東 雅之

    日本生物工学会大会講演要旨集  2017.08  (公社)日本生物工学会

     More details

    Presentation type:Poster presentation  

  • 大腸菌フロック表面での組換えタンパク質固相発現 Domestic conference

    尾島 由紘,布上 翔太,東 雅之,田谷 正仁

    化学工学会第82年会, 東京  2017.03 

     More details

    Presentation type:Oral presentation (general)  

  • 微生物燃料電池の性能改善に向けた触媒開発 Invited Domestic conference

    福井 早紀,川口 太一,駒 大輔,大本 貴士,尾島 由紘,東 雅之

    第1回有機・バイオニクス研究会,寝屋川  2017.03 

     More details

    Presentation type:Oral presentation (general)  

  • ビス型第四アンモニウム塩を用いた高粘度培養液からの簡便なポリグルタミン酸回収法の検討と生じた複合体の利用 Domestic conference

    劉 涛,延嶋 浩文,尾島 由紘,東 雅之

    日本農芸化学会平成29年度大会, 京都  2017.03 

     More details

    Presentation type:Oral presentation (general)  

  • 大腸菌の外膜小胞産生とヒト腸管細胞への取込み Domestic conference

    尾島 由紘,東 雅之

    バイオインターフェース先端マテリアルの創生第7回シンポジウム,大阪  2017.02 

     More details

    Presentation type:Poster presentation  

  • 抗真菌薬に繋がる細胞壁形成阻害剤の新規スクリーニング法 Domestic conference

    根路銘 伸介,尾島 由紘,東 雅之

    バイオインターフェース先端マテリアルの創生第7回シンポジウム,大阪  2017.02 

     More details

    Presentation type:Poster presentation  

  • パン酵母の化学修飾と遺伝子改変によるレアメタル高吸着材料の開発 Domestic conference

    小硲 省吾,木原 摩耶,尾島 由紘,東 雅之

    第4回貴金属シンポ 貴金属の製錬・リサイクル技術の最前線,東京  2017.01 

     More details

    Presentation type:Poster presentation  

  • バイオ燃料電池に適した触媒微生物の開発 Invited Domestic conference

    東雅之

    グリーン・イノベーション 研究成果企業化促進フォーラム  2016.12 

     More details

    Presentation type:Symposium, workshop panel (nominated)  

  • 大腸菌フロック上での組換えタンパク質固相発現系の構築 Domestic conference

    尾島 由紘,布上 翔太,東 雅之,田谷 正仁

    日本生物工学会大会平成28年度大会, 富山  2016.09 

     More details

    Presentation type:Poster presentation  

  • 乳化を指標とした細胞壁形成阻害剤の新規スクリーニング法の検討 Domestic conference

    根路銘 伸介,尾島 由紘,東 雅之

    日本生物工学会大会平成28年度大会,富山  2016.09 

     More details

    Presentation type:Poster presentation  

  • 酵母の細胞表層多糖の改変と金属吸着 Domestic conference

    高橋 大地,松川 真弓,尾島 由紘,東 雅之

    日本生物工学会大会平成28年度大会, 富山  2016.09 

     More details

    Presentation type:Poster presentation  

  • 大腸菌グルコース燃料電池の出力向上を目指した糖代謝と呼吸鎖の改変 Domestic conference

    福井 早紀,駒 大輔,大本 貴士,尾島 由紘,東 雅之

    日本生物工学会大会平成28年度大会 富山  2016.09 

     More details

    Presentation type:Poster presentation  

  • バイオ燃料電池に適した触媒微生物の開発状況 Invited Domestic conference

    東雅之

    日本農芸化学会中部支部第177回例会ミニシンポジウム,名古屋  2016.09 

     More details

    Presentation type:Oral presentation (general)  

  • 酵母の細胞壁はどこまでわかったのか? その応用展開は? Invited Domestic conference

    東雅之

    近畿化学協会バイオ部会平成28年度第1回例会, 大阪  2016.07 

     More details

    Presentation type:Oral presentation (general)  

  • 自然界から単離したBacillus sp.が生産するポリグルタミン酸の特徴とその応用 Domestic conference

    劉 涛, 延島 浩文, 立花 太郎, 東 雅之

    日本生物工学会大会講演要旨集  2015.09  (公社)日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

  • 細胞から乳化物質を遊離する酵母変異株と乳化活性物質の解析 Domestic conference

    大西 将也, 松本 あずさ, 根路銘 伸介, 立花 太郎, 東 雅之

    日本生物工学会大会講演要旨集  2015.09  (公社)日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

  • 細胞骨格制御因子Septin9に対するモノクローナル抗体の作製(Production of monoclonal antibodies directed against Septin9) Domestic conference

    Shimada Shun, Yoshimi Tomohiko, Azuma Masayuki, Tachibana Taro

    日本細胞生物学会大会講演要旨集  2013.05  (一社)日本細胞生物学会

     More details

    Presentation type:Oral presentation (general)  

  • 免疫活性化能をもつ酵母の細胞表層構造の解析 Domestic conference

    溝渕 彩乃, 高田 裕紀, 立花 太郎, 東 雅之

    日本生物工学会大会講演要旨集  2012.09  (公社)日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

▼display all

Collaborative research (seeds) keywords

  • 抗真菌剤

    Category:Life Science 

  • 乳化剤

    Category:Chemicals / Nano-technology / Materials 

  • 微生物燃料電池

    Category:Green Technology 

  • 金属吸着剤

    Category:Green Technology 

  • 細胞工学

    Category:Life Science 

  • 応用微生物

    Category:Life Science 

▼display all

Outline of collaborative research (seeds)

  • 酵母由来の乳化物質の応用

    2017年から可能

     More details

    Request for collaborative research:The private sector, such as other institutions

    Type of research exchange:Technical consultation, Contract research, Joint research, Lecture

    Application fields / methods etc:新規な生理活性物質の探索や有用酵素の生産を行う。

    Core knowledge, technology, information etc:遺伝子、培養、微生物、酵素

    Expected ripple effect:環境にやさしい生産技術、有用物質の発見

    Detail description:微生物にまつわる話しなら何でもOK

    Advantages and features compared to previous research:遺伝情報を最大限に活用

    Comment:特になし

  • 抗真菌剤の開発

     More details

    Request for collaborative research:The private sector, such as other institutions

    Type of research exchange:Technical consultation, Contract research, Joint research, Lecture

  • 微生物を用いた発酵生産

     More details

    Request for collaborative research:The private sector, such as other institutions

    Type of research exchange:Technical consultation, Contract research, Joint research, Lecture

  • 微生物燃料電池に関する研究

     More details

    Request for collaborative research:The private sector, such as other institutions

    Type of research exchange:Technical consultation, Contract research, Joint research, Lecture

  • 酵母を用いた有用金属回収、有害重金属除去技術の開発

     More details

    Request for collaborative research:The private sector, such as other institutions

    Type of research exchange:Technical consultation, Contract research, Joint research, Lecture

Grant-in-Aid for Scientific Research

  • 微生物燃料電池の高出力化に向けた高度に機能集約した大腸菌触媒の開発

    Grant-in-Aid for Scientific Research(C)  2021.04

  • バイオ燃料電池に有益な機能を高度に集約した燃料電池用スーパー大腸菌の開発

    Grant-in-Aid for Scientific Research(C)  2017.04

  • 大腸菌への機能集約によるバイオ燃料電池に最適な微生物触媒の開発

    Grant-in-Aid for Scientific Research(C)  2014.04

  • 鮮類(ケヘチマゴケ)を用いる有毒重金属イオンの除去

    萌芽的研究  1998

Incentive donations / subsidies

  • 有価金属や有害金属の除去・回収を可能とする低環境負荷型高性能金属吸着材料の開発

    国立研究開発法人科学技術振興機構(JST)  2021.09

Acceptance of Researcher

  • 2022  Number of researchers:1

Outline of education staff

  • Cell and Genetic Engineering, Cell Engineering, Industrial Microbiology, Introduction of Bio-industries, Advanced Cell Engineering

Charge of on-campus class subject

  • 産業微生物学

    2021     Undergraduate

  • 産業微生物学

    2020     Undergraduate

  • 産業微生物学

    2019     Undergraduate

  • Industrial microbiology

    2018     Undergraduate

  • Industrial Microbiology,

    2017     Undergraduate

  • 細胞遺伝子工学

    2021     Undergraduate

  • 細胞遺伝子工学

    2020     Undergraduate

  • 細胞遺伝子工学

    2019     Undergraduate

  • Cell and genetic engineering

    2018     Undergraduate

  • 細胞工学

    2021     Undergraduate

  • 細胞工学

    2020     Undergraduate

  • 細胞工学

    2019     Undergraduate

  • Cell engineering

    2018     Undergraduate

  • Cell Engineering

    2017     Undergraduate

  • Cell Engineering 2

    2017     Undergraduate

  • 展開バイオ工学

    2021     Undergraduate

  • 展開バイオ工学

    2020     Undergraduate

  • 展開バイオ工学

    2019     Undergraduate

  • Introduction of bio-industries

    2018     Undergraduate

  • Introduction of Bio-industries

    2017     Undergraduate

  • 細胞利用工学特論

    2021     Graduate school

  • 細胞利用工学特論

    2020     Graduate school

  • 細胞利用工学特論

    2019     Graduate school

  • Advanced cell engineering

    2018     Graduate school

  • Advanced Cell Engineering

    2017     Graduate school

  • 特別演習  前期特別演習  化学生物系ゼミナール  後期特別研究

    2021     Graduate school

  • 特別演習  前期特別演習  化学生物系ゼミナール  後期特別研究

    2020     Graduate school

  • 特別演習  前期特別演習  化学生物系ゼミナール  後期特別研究

    2019     Graduate school

  • 特別演習  前期特別演習  化学生物系ゼミナール  後期特別研究

    2018     Graduate school

  • 特別演習  前期特別演習  化学生物系ゼミナール  後期特別研究

    2017     Graduate school

  • 化学バイオ工学実験Ⅱ

    2021     Undergraduate

  • 化学バイオ工学実験Ⅱ

    2020     Undergraduate

  • 化学バイオ工学実験Ⅱ

    2019     Undergraduate

  • 化学バイオ工学実験Ⅱ

    2018     Undergraduate

  • 化学バイオ工学実験Ⅱ

    2017     Undergraduate

  • 化学バイオ工学特論Ⅰ, Ⅱ

    2021     Undergraduate

  • 化学バイオ工学特論Ⅰ, Ⅱ

    2020     Undergraduate

  • 化学バイオ工学特論Ⅰ, Ⅱ

    2019     Undergraduate

  • 化学バイオ工学特論Ⅰ, Ⅱ

    2018     Undergraduate

  • 化学バイオ工学特論Ⅰ, Ⅱ

    2017     Undergraduate

  • 卒業研究Ⅰ, Ⅱ

    2021     Undergraduate

  • 卒業研究Ⅰ, Ⅱ

    2020     Undergraduate

  • 卒業研究Ⅰ, Ⅱ

    2019     Undergraduate

  • 卒業研究Ⅰ, Ⅱ

    2018     Undergraduate

  • 卒業研究Ⅰ, Ⅱ

    2017     Undergraduate

  • 技術と生命

    2020     Undergraduate

  • 物質化学生命系特別演習

    2022   Intensive lecture   Graduate school

  • 物質化学生命系特別演習第1

    2022   Intensive lecture   Graduate school

  • 卒業研究Ⅰ

    2022   Intensive lecture   Undergraduate

  • 細胞工学

    2022   Weekly class   Undergraduate

  • 細胞遺伝子工学

    2022   Weekly class   Undergraduate

  • 化学バイオ工学特論Ⅰ

    2022   Intensive lecture   Undergraduate

  • 化学バイオ工学概論

    2022   Intensive lecture   Undergraduate

  • 物質化学生命系特別研究 (化学バイオ工学分野)

    2022   Intensive lecture   Graduate school

  • 物質化学生命系特別演習第2 (化学バイオ工学分野)

    2022   Intensive lecture   Graduate school

  • 酵素工学特論 (化学バイオ工学分野)

    2022   Intensive lecture   Graduate school

  • 細胞利用工学特論 (化学バイオ工学分野)

    2022   Weekly class   Graduate school

  • 特別演習(化学生物系2回生)

    2022   Intensive lecture   Graduate school

  • 前期特別研究(化学生物系)

    2022   Intensive lecture   Graduate school

  • 後期特別研究(化学生物系)

    2022   Intensive lecture   Graduate school

  • ゼミナール(化学生物系)

    2022   Intensive lecture   Graduate school

  • 卒業研究

    2022   Intensive lecture   Undergraduate

  • 産業微生物学

    2022   Weekly class   Undergraduate

  • バイオ工学実験

    2022   Weekly class   Undergraduate

  • バイオ英語演習

    2022   Weekly class   Undergraduate

  • 展開バイオ工学

    2022   Weekly class   Undergraduate

  • 化学バイオ工学特論

    2022   Intensive lecture   Undergraduate

▼display all

Charge of off-campus class subject

  • 生命機能化学特殊講義B

    Institution:Osaka Prefecture University

  • 生体化学基礎

    Institution:Kinki University

  • 細胞生物学

    Institution:Osaka City University

  • 微生物学

    Institution:Osaka City University

Faculty development activities

  • FD活動への貢献   2022

     More details

    各種FD集会に参加、分野FD集会で教育、入試に関して議論

  • FD活動への貢献  2021

     More details

    全学、学科/専攻のFD集会に参加、議論

  • FD活動への貢献  2020

     More details

    全学、学科/専攻のFD集会に参加、議論

  • FD活動への貢献  2019

     More details

    全学、学科/専攻のFD集会に参加、議論

  • FD活動への貢献  2018

     More details

    全学、学科/専攻のFD集会に参加、議論

Number of papers published by graduate students

  • 2022

    Number of undergraduate student / college student presentations:Number of graduate students presentations:8

Number of instructed thesis, researches

  • 2022

    Number of instructed the graduation thesis:Number of graduation thesis reviews:6

    [Number of instructed the Master's Program] (previous term):[Number of instructed the Master's Program] (letter term):4

    [Number of master's thesis reviews] (chief):[Number of master's thesis reviews] (vice-chief):12

    [Number of doctoral thesis reviews] (chief):[Number of doctoral thesis reviews] (vice-chief):1

Original item・Special report (Education Activity)

  • 2019

      More details

    Original item:展開バイオ工学において非常勤教員と工場・研究所見学を企画/引率(3件)

  • 2018

      More details

    Original item:展開バイオ工学において非常勤教員と工場・研究所見学を企画/引率(2件)

  • 2018

      More details

    Original item:「大阪市立大学はばたけ夢基金」による学生の海外留学・海外渡航の書類審査に協力

Visiting Lectures ⇒ Link to the list of Visiting Lectures

  • 微生物応用/発酵/細胞工学/生化学に関する内容

    Category:Modern system science (knowledge information system, environmental system, educational welfare, psychology), Commerce (management, public management), Economics, Law (law, politics, administration), Literature (literature, philosophy, history, art, human behavior, language, culture, society / gender), Science (mathematics, physics, chemistry, biology, geology, biochemistry), Engineering (machinery, electronics / physics, electrical / electronics, electrical information, chemical biotechnology, architecture, cities (civil engineering / environment), material chemistry, aerospace, marine systems, applied chemistry, chemistry, materials), Life sciences (food, nutrition science, living environment, human welfare), Agricultural science (applied biology, biofunctional chemistry, green space environmental science), Medicine (medical care, rehabilitation, health exercise science, physical fitness / training, sports practice science), Nursing (nursing, sex education), Veterinary

     More details

    Audience:Schoolchildren, Junior high school students, High school students, College students, Graduate students, Teachers, Guardians, Researchers, General, Scientific organization, Company, Civic organization, Media

    酵母を中心とした応用微生物、微生物による発酵生産、細胞工学や合成生物学的手法による有用細胞の構築、自然界からの有用微生物の探索、微生物燃料電池、基本的な生化学

Foreigner acceptance

  • 2022

    International Students :3

  • 2020

    International Students :1

  • 2019

    International Students :1

  • 2018

    foreigners accepted :0

    International Students :0

  • 2017

    foreigners accepted :0

    International Students :0

  • 2016

    International Students :1

  • 2015

    International Students :1

  • 2014

    International Students :2

  • 2013

    International Students :2

  • 2012

    International Students :2

▼display all

International exchange activities

  • 公益財団法人ナインティナイン・アジア留学生奨学基金理事として運営に協力

    Field category :Social contributions

    2021.04 - Now

Other

  • Job Career

    2007.04 - Now

  • Job Career

    1999.04 - 2007.03

  • Job Career

    1996.04 - 1999.03