-
Stromal area differences with epithelial-mesenchymal transition gene changes in conjunctival and orbital mucosa-associated lymphoid tissue lymphoma
Reviewed
Tagami M, Kasashima H, Kakehashi A, Yoshikawa A, Nishio M, Misawa N, Sakai A, Wanibuchi H, Yashiro M, Azumi A, Honda S
14
1277749
2024.01（ ISSN:2234-943X
）
-
Evaluation of the Mechanisms Involved in the Development of Bladder Toxicity following Exposure to Occupational Bladder Cancer Causative Chemicals Using DNA Adductome Analysis
Reviewed
International coauthorship
Suzuki S, Gi M, Komiya M, Obikane A, Vachiraarunwong A, Fujioka M, Kakehashi A, Totsuka Y, Wanibuchi H
14
(
1
)
2023.12
-
DNA Methylation Aberrations in Dimethylarsinic Acid-Induced Bladder Carcinogenesis.
Reviewed
Yamamoto T, Gi M, Yamashita S, Suzuki S, Fujioka M, Vachiraarunwong A, Guo R, Qiu G, Kakehashi A, Kato M, Uchida J, Wanibuchi H
Cancers
15
(
21
)
2023.11（ ISSN:2072-6694
）
-
Recent Insights into the Biomarkers, Molecular Targets and Mechanisms of Non-Alcoholic Steatohepatitis-Driven Hepatocarcinogenesis.
Reviewed
Kakehashi A, Suzuki S, Wanibuchi H
Cancers
15
(
18
)
2023.09（ ISSN:2072-6694
）
-
Dimethylarsinic acid induces bladder carcinogenesis via the amphiregulin pathway.
Reviewed
Shugo Suzuki, Min Gi, Masaki Fujioka, Anna Kakehashi, Hideki Wanibuchi
Toxicology Letters
384
128
-
135
2023.08（ ISSN:0378-4274
）
-
o-Toluidine metabolism and effects in the urinary bladder of humanized-liver mice.
Reviewed
Yuka Yokota, Shugo Suzuki, Min Gi, Yukie Yanagiba, Nao Yoneda, Masaki Fujioka, Anna Kakehashi, Shigeki Koda, Hiroshi Suemizu, Hideki Wanibuchi
Toxicology
488
153483
-
153483
2023.04（ ISSN:0300-483X
）
-
Safety and Feasibility of Contrast-Enhanced Computed Tomography with a Nanoparticle Contrast Agent for Evaluation of Diethylnitrosamine-Induced Liver Tumors in a Rat Model.
Reviewed
Nota T, Kageyama K, Yamamoto A, Kakehashi A, Yonezawa H, Jogo A, Sohgawa E, Murai K, Ogawa S, Miki Y
Academic Radiology
30
(
1
)
30
-
39
2023.01（ ISSN:1076-6332
）
-
The carbonic anhydrase inhibitor acetazolamide inhibits urinary bladder cancers via suppression of β-catenin signaling.
Reviewed
Taisuke Matsue, Min Gi, Masayuki Shiota, Hirokazu Tachibana, Shugo Suzuki, Masaki Fujioka, Anna Kakehashi, Tomoki Yamamoto, Minoru Kato, Junji Uchida, Hideki Wanibuchi
Cancer science
113
(
8
)
2642
-
2653
2022.08（ ISSN:1347-9032
）
-
Response biomarkers of inhalation exposure to cigarette smoke in the mouse lung
Reviewed
Suzuki Shugo, Asai Kazuhisa, Gi Min, Kojima Kazuya, Kakehashi Anna, Oishi Yuji, Matsue Taisuke, Yukimatsu Nao, Hirata Kazuto, Kawaguchi Tomoya, Wanibuchi Hideki
Journal of Toxicologic Pathology
35
(
3
)
247
-
254
2022.07（ ISSN:0914-9198
）
-
FOXP3 and CXCR4-positive regulatory T cells in the tumor stroma as indicators of tumor immunity in the conjunctival squamous cell carcinoma microenvironment.
Reviewed
Tagami M, Kakehashi A, Katsuyama-Yoshikawa A, Misawa N, Sakai A, Wanibuchi H, Azumi A, Honda S
PloS one
17
(
3
)
e0263895
2022
-
Expression of thrombospondin-1 in conjunctival squamous cell carcinoma is correlated to the Ki67 index and associated with progression-free survival.
Reviewed
Tagami M, Kakehashi A, Sakai A, Misawa N, Katsuyama-Yoshikawa A, Wanibuchi H, Azumi A, Honda S
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
259
(
10
)
3127
-
3136
2021.10（ ISSN:0721-832X
）
-
Canopy Homolog 2 as a Novel Molecular Target in Hepatocarcinogenesis.
Reviewed
Anna Kakehashi, Shugo Suzuki, Masayuki Shiota, Nina Raymo, Min Gi, Taro Tachibana, Vasily Stefanov, Hideki Wanibuchi
Cancers
13
(
14
)
2021.07（ ISSN:2072-6694
）
-
Cache Domain Containing 1 Is a Novel Marker of Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis
Reviewed
International coauthorship
13
(
6
)
1216
2021.03
-
Accumulation of 8-hydroxydeoxyguanosine, L-arginine and glucose metabolites by liver tumor cells are the important characteristic features of metabolic syndrome and non-alcoholic steatohepatitis-associated hepatocarcinogenesis
Reviewed
International coauthorship
Anna Kakehashi, Shugo Suzuki, Naomi Ishii, Takahiro Okuno, Yuko Kuwae, Masaki Fujioka, Min Gi, Vasily Stefanov, Hideki Wanibuchi
International Journal of Molecular Sciences
21
(
20
)
7746
2020.10
-
Expression, intracellular localization, and mutation of EGFR in conjunctival squamous cell carcinoma and the association with prognosis and treatment
Reviewed
Atsushi Sakai, Mizuki Tagami, Anna Kakehashi, Atsuko Katsuyama-Yoshikawa, Norihiko Misawa, Hideki Wanibuchi, Atsushi Azumi, Shigeru Honda
PLoS One
15
(
8
)
e0238120
2020.08
-
Role of γ-H2AX as a biomarker for detection of bladder carcinogens in F344 rats.
Reviewed
Shugo Suzuki, Min Gi, Takeshi Toyoda, Hiroyuki Kato, Aya Naiki-Ito, Anna Kakehashi, Kumiko Ogawa, Satoru Takahashi, Hideki Wanibuchi
Journal of Toxicologic Pathology
33
(
4
)
279
-
285
2020.08
-
Dimethylarsinic acid (DMA) enhanced lung carcinogenesis via histone H3K9 modification in a transplacental mouse model
Reviewed
Fujioka Masaki, Suzuki Shugo, Gi Min, Kakehashi Anna, Oishi Yuji, Okuno Takahiro, Yukimatsu Nao, Wanibuchi Hideki
ARCHIVES OF TOXICOLOGY
2020.02（ ISSN:0340-5761
）
-
Promotion effects of acetoaceto-o-toluidide on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder carcinogenesis in rats
Reviewed
Yukimatsu Nao, Gi Min, Okuno Takahiro, Fujioka Masaki, Suzuki Shugo, Kakehashi Anna, Yanagiba Yukie, Suda Megumi, Koda Shigeki, Nakatani Tatsuya, Wanibuchi Hideki
ARCHIVES OF TOXICOLOGY
93
(
12
)
3617
-
3631
2019.12（ ISSN:0340-5761
）
-
Quantitative analysis of mutagenicity and carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in F344 gpt delta transgenic rats
Reviewed
Gi Min, Fujioka Masaki, Totsuka Yukari, Matsumoto Michiharu, Masumura Kenichi, Kakehashi Anna, Yamaguchi Takashi, Fukushima Shoji, Wanibuchi Hideki
MUTAGENESIS
34
(
3
)
279
-
287
2019.05（ ISSN:0267-8357
）
-
Acetoaceto-o-toluidide enhances cellular proliferative activity in the urinary bladder of rats.
Reviewed
Takahiro Okuno, Min Gi, Masaki Fujioka, Nao Yukimatu, Anna Kakehashi, Akito Takeuchi , Gingi Endo , Yoko Endo, Hideki Wanibuchi
TOXICOLOGICAL SCIENCES
169
(
2
)
456
-
464
2019.02（ ISSN:1096-6080
）
-
A chronic toxicity study of diphenylarsinic acid in the drinking water of C57BL/6J mice for 52 weeks.
Reviewed
Takashi Yamaguchi, Min Gi, Masaki Fujioka, Yoshiyuki Tago, Anna Kakehashi, Hideki Wanibuchi
JOURNAL OF TOXICOLOGIC PATHOLOGY
32
(
3
)
127
-
134
2019（ ISSN:0914-9198
）
-
Chronic dietary toxicity and carcinogenicity studies of dammar resin in F344 rats.
Reviewed
Min Gi, Masaki Fujioka, Shotaro Yamano, Anna Kakehashi, Yuji Oishi, Takahiro Okuno, Nao Yukimatsu, Takashi Yamaguchi, Yoshiyuki Tago, Mitsuaki Kitano, Shim-mo, Hideki Wanibuchi
ARCHIVES OF TOXICOLOGY
92
(
12
)
3565
-
3583
2018.12（ ISSN:0340-5761
）
-
mTOR activation in liver tumors is associated with metabolic syndrome and non-alcoholic steatohepatitis in both mouse models and humans.
Reviewed
Takahiro Okuno, Anna Kakehashi, Naomi Ishii, Masaki Fujioka, Min Gi, Hideki Wanibuchi
CANCERS
10
(
12
)
2018.12（ ISSN:2072-6694
）
-
Steroid sulfatase promotes invasion through epithelial-mesenchymal transition and predicts the progression of bladder cancer.
Reviewed
Yasuomi Shimizu, Satoshi Tamada, Minoru Kato, Yuji Takeyama, Masaki Fujioka, Anna Kakehashi, Tatsuya Nakatani, Hideki Wanibuchi, Min Gi
EXPERIMENTAL AND THERAPEUTIC MEDICINE
16
(
6
)
4463
-
4470
2018.12（ ISSN:1792-0981
）
-
Quantitative Approaches to Assess Key Carcinogenic Events of Genotoxic Carcinogens.
Reviewed
Shoji Fukushima, Min Gi, Masaki Fujioka, Anna Kakehashi, Hideki Wanibuchi, Michiharu Matsumoto
TOXICOLOGICAL RESEARCH
34
(
4
)
291
-
296
2018.10（ ISSN:1976-8257
）
-
In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats.
Reviewed
Min Gi, Masaki Fujioka, Anna Kakehashi, Takahiro Okuno, Kenichi Masumura, Takehiko Nohmi, Michiharu Matsumoto, Masako Omori, Hideki Wanibuchi, Shoji Fukushima
ARCHIVES OF TOXICOLOGY
92
(
10
)
3207
-
3221
2018.10（ ISSN:0340-5761
）
-
Carcinogenicity induced by prenatal exposure to dimethylarsinic acid in CD1 mice
Reviewed
Masaki Fujioka, Min Gi, Kenji Kumada, Takahiro Okuno, Anna Kakehashi, Hideki Wanibuchi
CANCER SCIENCE
109
584
-
584
2018.01（ ISSN:1349-7006
）
-
Inhibitory effects of acetazolamide on the BBN-induced mouse bladder carcinogenesis
Reviewed
Min Gi , Masaki Fujioka, Anna Kakehashi, Takahiro Okuno, Yuki Kouyama, Kenji Kumada, Hideki Wanibuchi
CANCER SCIENCE
109
305
-
305
2018.01（ ISSN:1349-7006
）
-
Roles of Ink4a/Arf in BBN-induced mouse bladder carcinogenesis
Reviewed
Kohyama Yuki, Gi Min, Fujioka Masaki, Kumada Kenji, Okuno Takahiro, Kakehashi Anna, Wanibuchi Hideki
CANCER SCIENCE
109
167
-
167
2018.01（ ISSN:1349-7006
）
-
Proteome characteristics of non-alcoholic steatohepatitis liver tissue and associated hepatocellular carcinomas.
Reviewed
109
584
-
584
2018.01（ ISSN:1349-7006
）
-
F344ラットへのジフェニルアルシン酸含有飲料水104週間投与の発癌性に関する検討(A carcinogenicity study of diphenylarsinic acid in F344 rats in drinking water for 104 weeks)
Reviewed
Yamaguchi Takashi, Gi Min, Fujioka Masaki, Doi Kenichiro, Okuno Takahiro, Kakehashi Anna, Wanibuchi Hideki
(一社)日本毒性学会 The Journal of Toxicological Sciences
42
(
4
)
475
-
483
2017.08（ ISSN:0388-1350
）
-
Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis
Reviewed
Kakehashi Anna, Ishii Naomi, Okuno Takahiro, Fujioka Masaki, Gi Min, Wanibuchi Hideki
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
18
(
8
)
2017.08（ ISSN:1422-0067
）
-
Carbonic anhydrase 2 is a novel invasion-associated factor in urinary bladder cancers
Reviewed
Tachibana Hirokazu, Gi Min, Kato Minoru, Yamano Shotaro, Fujioka Masaki, Kakehashi Anna, Hirayama Yukiyoshi, Koyama Yuki, Tamada Satoshi, Nakatani Tatsuya, Wanibuchi Hideki
CANCER SCIENCE
108
(
3
)
331
-
337
2017.03（ ISSN:1349-7006
）
-
Proteome Characteristics of Non-Alcoholic Steatohepatitis Liver Tissue and Associated Hepatocellular Carcinomas
Reviewed
Kakehashi Anna, Stefanov Vasily E., Ishii Naomi, Okuno Takahiro, Fujii Hideki, Kawai Kazuaki, Kawada Norifumi, Wanibuchi Hideki
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
18
(
2
)
2017.02（ ISSN:1422-0067
）
-
A chronic toxicity study of diphenylarsinic acid in F344 rats in drinking water for 52 weeks
Reviewed
Yamaguchi Takashi, Gi Min, Yamano Shotarou, Fujioka Masaki, Tatsumi Kumiko, Kawachi Satoko, Ishii Naomi, Doi Kenichiro, Kakehashi Anna, Wanibuchi Hideki
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
69
(
1
)
1
-
7
2017.01（ ISSN:0940-2993
）
-
A carcinogenicity study of diphenylarsinic acid in F344 rats in drinking water for 104 weeks.
Reviewed
Yamaguchi T, Gi M, Fujioka M, Doi K, Okuno T, Kakehashi A, Wanibuchi H
一般社団法人 日本毒性学会 The Journal of toxicological sciences
42
(
4
)
475
-
483
2017（ ISSN:0388-1350
）
-
Diphenylarsinic acid exerts promotion effects on hepatobiliary carcinogenesis in a rat medium-term multiorgan carcinogenicity bioassay
Reviewed
Ishii Naomi, Gi Min, Fujioka Masaki, Yamano Shotaro, Okumura Mai, Kakehashi Anna, Wanibuchi Hideki
日本毒性病理学会 JOURNAL OF TOXICOLOGIC PATHOLOGY
30
(
1
)
39
-
45
2017（ ISSN:0914-9198
）
-
Progression of Hepatic Adenoma to Carcinoma in Ogg1 Mutant Mice Induced by Phenobarbital
Reviewed
Kakehashi Anna, Ishii Naomi, Okuno Takahiro, Fujioka Masaki, Gi Min, Fukushima Shoji, Wanibuchi Hideki
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
2017
8541064
2017（ ISSN:1942-0900
）
-
Chemopreventive Action by Ethanol-extracted Brazilian Green Propolis on Post-initiation Phase of Inflammation-associated Rat Colon Tumorigenesis
Reviewed
Doi Kenichiro, Fujioka Masaki, Sokuza Yui, Ohnishi Mariko, Gi Min, Takeshita Masanori, Kumada Kenji, Kakehashi Anna, Wanibuchi Hideki
IN VIVO
31
(
2
)
187
-
197
2017（ ISSN:0258-851X
）
-
Examination of in vivo mutagenicity of sodium arsenite and dimethylarsinic acid in gpt delta rats
Reviewed
Fujioka Masaki, Gi Min, Kawachi Satoko, Tatsumi Kumiko, Ishii Naomi, Doi Kenichiro, Kakehashi Anna, Wanibuchi Hideki
JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA
49
125
-
130
2016.11（ ISSN:1001-0742
）
-
Pueraria mirifica Exerts Estrogenic Effects in the Mammary Gland and Uterus and Promotes Mammary Carcinogenesis in Donryu Rats
Reviewed
Kakehashi Anna, Yoshida Midori, Tago Yoshiyuki, Ishii Naomi, Okuno Takahiro, Gi Min, Wanibuchi Hideki
TOXINS
8
(
11
)
2016.11（ ISSN:2072-6651
）
-
Ethanol-Extracted Brazilian Propolis Exerts Protective Effects on Tumorigenesis in Wistar Hannover Rats
Reviewed
Kakehashi Anna, Ishii Naomi, Fujioka Masaki, Doi Kenichiro, Gi Min, Wanibuchi Hideki
PLOS ONE
11
(
7
)
e0158654
2016.07（ ISSN:1932-6203
）
-
Qualitative and Quantitative Assessments on Low-Dose Carcinogenicity of Genotoxic Hepatocarcinogens: Dose-Response for Key Events in Rat Hepatocarcinogenesis
Reviewed
Shoji Fukushima, Min Gi, Anna Kakehashi, Hideki Wanibuchi
Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation
1
-
17
2016.05
-
CD44 variant 9 is a potential biomarker of tumor initiating cells predicting survival outcome in hepatitis C virus-positive patients with resected hepatocellular carcinoma
Reviewed
Kakehashi Anna, Ishii Naomi, Sugihara Eiji, Gi Min, Saya Hideyuki, Wanibuchi Hideki
CANCER SCIENCE
107
(
5
)
609
-
618
2016.05（ ISSN:1349-7006
）
-
Qualitative and quantitative approaches in the dose-response assessment of genotoxic carcinogens
Reviewed
Fukushima Shoji, Gi Min, Kakehashi Anna, Wanibuchi Hideki, Matsumoto Michiharu
MUTAGENESIS
31
(
3
)
341
-
346
2016.05（ ISSN:0267-8357
）
-
Preventive Effects of Spirogyra neglecta and a Polysaccharide Extract against Dextran Sodium Sulfate Induced Colitis in Mice.
Reviewed
Taya S, Kakehashi A, Wongpoomchai R, Gi M, Ishii N, Wanibuchi H
Asian Pacific journal of cancer prevention : APJCP
17
(
4
)
2235
-
45
2016（ ISSN:1513-7368
）
-
Modifying effects of 1,2-dichloropropane on N-nitrosobis(2-oxopropyl)amine-induced cholangiocarcinogenesis in male Syrian hamsters
Reviewed
Gi Min, Fujioka Masaki, Yamano Shotaro, Shimomura En I., Kanki Masayuki, Kawachi Satoko, Tachibana Hirokazu, Tatsumi Kumiko, Fang He, Ishii Naomi, Kakehashi Anna, Wanibuchi Hideki
JOURNAL OF TOXICOLOGICAL SCIENCES
40
(
5
)
647
-
656
2015.10（ ISSN:0388-1350
）
-
Ethanol-extracted propolis enhances BBN-initiated urinary bladder carcinogenesis via non-mutagenic mechanisms in rats
Reviewed
Xie Xiao-Li, Gi Min, Fujioka Masaki, Doi Kenichiro, Yamano Shotaro, Tachibana Hirokazu, Fang He, Kakehashi Anna, Wanibuchi Hideki
FOOD AND CHEMICAL TOXICOLOGY
83
193
-
200
2015.09（ ISSN:0278-6915
）
-
Integrative analyses of miRNA and proteomics identify potential biological pathways associated with onset of pulmonary fibrosis in the bleomycin rat model
Reviewed
Fukunaga Satoki, Kakehashi Anna, Sumida Kayo, Kushida Masahiko, Asano Hiroyuki, Gi Min, Wanibuchi Hideki
TOXICOLOGY AND APPLIED PHARMACOLOGY
286
(
3
)
188
-
197
2015.08（ ISSN:0041-008X
）
-
Novel biomarkers for gastric cancer stem cells utilizing comparative proteomics analysis
Reviewed
Yashiro Masakazu, Morisaki Tamami, Hasegawa Tsuyoshi, Kakehashi Anna, Kinoshita Haruhito, Fukuoka Tatsunari, Kasashima Hiroaki, Masuda Go, Sakurai Katsunobu, Kubo Naoshi, Tanaka Hiroaki, Muguruma Kazuya, Ohira Masaichi, Wanibuchi Hideki, Hirakawa Kosei
CANCER RESEARCH
75
2015.08（ ISSN:0008-5472
）
-
Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-Dichloropropane in Male Syrian Hamsters and B6C3F1 Mice
Reviewed
Gi Min, Fujioka Masaki, Yamano Shotaro, Shimomura Eri, Ishii Naomi, Kakehashi Anna, Takeshita Masanori, Wanibuchi Hideki
TOXICOLOGICAL SCIENCES
145
(
1
)
196
-
208
2015.05（ ISSN:1096-6080
）
-
Paraneoplastic Ma Antigen-Like 1 as a Potential Prognostic Biomarker in Human Pancreatic Ductal Adenocarcinoma
Reviewed
Kuwae Yuko, Kakehashi Anna, Wakasa Kenichi, Wei Min, Yamano Shotaro, Ishii Naomi, Ohsawa Masahiko, Wanibuchi Hideki
PANCREAS
44
(
1
)
106
-
115
2015.01（ ISSN:0885-3177
）
-
Induction of cell proliferation in the rat liver by the short-term administration of ethyl tertiary-butyl ether.
Reviewed
Kakehashi A, Hagiwara A, Imai N, Wei M, Fukushima S, Wanibuchi H
日本毒性病理学会 Journal of toxicologic pathology
28
(
1
)
27
-
32
2015.01（ ISSN:0914-9198
）
-
エチル-ターシャリー-ブチルエーテルを短期投与したラット肝臓における細胞増殖の誘導(Induction of cell proliferation in the rat liver by the short-term administration of ethyl tertiary-butyl ether)
Reviewed
Kakehashi Anna, Hagiwara Akihiro, Imai Norio, Wei Min, Fukushima Shoji, Wanibuchi Hideki
日本毒性病理学会 Journal of Toxicologic Pathology
28
(
1
)
27
-
32
2015.01（ ISSN:0914-9198
）
-
Modifying effects of 1,2-dichloropropane on N-nitrosobis(2-oxopropyl)amine-induced cholangiocarcinogenesis in male Syrian hamsters.
Reviewed
Gi M, Fujioka M, Yamano S, Shimomura E, Kanki M, Kawachi S, Tachibana H, Tatsumi K, Fang H, Ishii N, Kakehashi A, Wanibuchi H
一般社団法人 日本毒性学会 The Journal of toxicological sciences
40
(
5
)
647
-
56
2015（ ISSN:0388-1350
）
-
Valerian Inhibits Rat Hepatocarcinogenesis by Activating GABA(A) Receptor-Mediated Signaling
Reviewed
Kakehashi Anna, Kato Ayumi, Ishii Naomi, Wei Min, Morimura Keiichirou, Fukushima Shoji, Wanibuchi Hideki
PLOS ONE
9
(
11
)
e113610
2014.11（ ISSN:1932-6203
）
-
Comparative Proteomics Analysis of Gastric Cancer Stem Cells
Reviewed
Morisaki Tamami, Yashiro Masakazu, Kakehashi Anna, Inagaki Azusa, Kinoshita Haruhito, Fukuoka Tatsunari, Kasashima Hiroaki, Masuda Go, Sakurai Katsunobu, Kubo Naoshi, Muguruma Kazuya, Ohira Masaichi, Wanibuchi Hideki, Hirakawa Kosei
PLOS ONE
9
(
11
)
e110736
2014.11（ ISSN:1932-6203
）
-
Threshold of Genotoxic Carcinogens: Consideration from No-Effect Doses for Cancer-Related Markers in Chemical Carcinogenesis
Reviewed
Fukushima Shoji, Gi Min, Kakehashi Anna, Wanibuchi Hideki
MUTAGENESIS
29
(
6
)
554
-
554
2014.11（ ISSN:0267-8357
）
-
A Comparative Study of Clinicopathological Features Between Simple Bone Cysts of the Calcaneus and the Long Bone
Reviewed
Takada Jun, Hoshi Manabu, Oebisu Naoto, Ieguchi Makoto, Kakehashi Anna, Wanibuchi Hideki, Nakamura Hiroaki
FOOT & ANKLE INTERNATIONAL
35
(
4
)
374
-
382
2014.04（ ISSN:1071-1007
）
-
Mode of action of ethyl tertiary-butyl ether hepatotumorigenicity in the rat: Evidence for a role of oxidative stress via activation of CAR, PXR and PPAR signaling pathways
Reviewed
Kakehashi Anna, Hagiwara Akihiro, Imai Norio, Nagano Kasuke, Nishimaki Fukumi, Banton Marcy, Wei Min, Fukushima Shoji, Wanibuchi Hideki
TOXICOLOGY AND APPLIED PHARMACOLOGY
273
(
2
)
390
-
400
2013.12（ ISSN:0041-008X
）
-
Novel medium-term carcinogenesis model for lung squamous cell carcinoma induced by N-nitrosotris-chloroethylurea in mice
Reviewed
Tago Yoshiyuki, Yamano Shotaro, Wei Min, Kakehashi Anna, Kitano Mitsuaki, Fujioka Masaki, Ishii Naomi, Wanibuchi Hideki
CANCER SCIENCE
104
(
12
)
1560
-
1566
2013.12（ ISSN:1349-7006
）
-
マウス膀胱発癌に及ぼすタバコ主流煙吸入による修飾作用の評価(Evaluation of the Modifying Effect of Inhalation of Mainstream Cigarette Smoke on Mouse Bladder Carcinogenesis)
Reviewed
Kato Minoru, Wei Min, Yamano Shotaro, Fujioka Masaki, Kakehashi Anna, Wanibuchi Hideki
日本毒性病理学会 Journal of Toxicologic Pathology
26
(
4
)
447
-
451
2013.12（ ISSN:0914-9198
）
-
Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DAN damage in rats
Reviewed
Wei Min, Yamada Takanori, Yamano Shotaro, Kato Minoru, Kakehashi Anna, Fujioka Masaki, Tago Yoshiyuki, Kitano Mistuaki, Wanibuchi Hideki
TOXICOLOGY AND APPLIED PHARMACOLOGY
273
(
1
)
1
-
9
2013.11（ ISSN:0041-008X
）
-
Oxidative stress in the carcinogenicity of chemical carcinogens.
Reviewed
Kakehashi A, Wei M, Fukushima S, Wanibuchi H
Cancers
5
(
4
)
1332
-
54
2013.10
-
Oncomodulin is a novel early marker of urinary bladder carcinogenesis in F344 rats
Reviewed
Okumura M., Wei M., Yamano S., Fujioka M., Kakehashi A., Wanibuchi H.
EUROPEAN JOURNAL OF CANCER
49
S198
-
S199
2013.09（ ISSN:0959-8049
）
-
L-Leucine and L-isoleucine enhance growth of BBN-induced urothelial tumors in the rat bladder by modulating expression of amino acid transporters and tumorigenesis-associated genes
Reviewed
Xie Xiao-Li, Kakehashi Anna, Wei Min, Yamano Shotaro, Takeshita Masanori, Yunoki Takayuki, Wanibuchi Hideki
FOOD AND CHEMICAL TOXICOLOGY
59
137
-
144
2013.09（ ISSN:0278-6915
）
-
Twenty-One Proteins Up-Regulated in Human H-ras Oncogene Transgenic Rat Pancreas Cancers are Up-Regulated in Human Pancreas Cancer
Reviewed
Yabushita Setsuko, Fukamachi Katsumi, Kikuchi Fumitake, Ozaki Masakazu, Miyata Kaori, Sukata Tokuo, Deguchi Yoshihito, Tanaka Hajime, Kakehashi Anna, Kawamura Satoshi, Uwagawa Satoshi, Wanibuchi Hideki, Suzui Masumi, Alexander David B., Tsuda Hiroyuki
PANCREAS
42
(
6
)
1034
-
1039
2013.08（ ISSN:0885-3177
）
-
Twenty-one proteins up-regulated in human H-ras oncogene transgenic rat pancreas cancers are up-regulated in human pancreas cancer.
Reviewed
Yabushita S, Fukamachi K, Kikuchi F, Ozaki M, Miyata K, Sukata T, Deguchi Y, Tanaka H, Kakehashi A, Kawamura S, Uwagawa S, Wanibuchi H, Suzui M, Alexander DB, Tsuda H
Pancreas
42
(
6
)
1034
-
9
2013.08（ ISSN:0885-3177
）
-
Clinicopathological significance of combined analysis of cytokeratin19 expression and preoperative serum CYFRA21-1 levels in human lung squamous cell carcinoma.
Reviewed
Hanada S, Nishiyama N, Mizuguchi S, Yamano S, Kakehashi A, Wei M, Inoue H, Komatsu H, Chung K, Suehiro S, Wanibuchi H
Osaka city medical journal
59
(
1
)
35
-
44
2013.06（ ISSN:0030-6096
）
-
ヒト肺扁平上皮がんにおけるサイトケラチン19の発現と術前血清CYFRA21-1濃度の複合分析の臨床病理学的な意義(Clinicopathological Significance of Combined Analysis of Cytokeratin19 Expression and Preoperative Serum CYFRA21-1 Levels in Human Lung Squamous Cell Carcinoma)
Reviewed
Hanada Shoji, Nishiyama Noritoshi, Mizuguchi Shinjiro, Yamano Shotaro, Kakehashi Anna, Wei Min, Inoue Hidetoshi, Komatsu Hiroaki, Chung Kyukwang, Suehiro Shigefumi, Wanibuchi Hideki
大阪市医学会 Osaka City Medical Journal
59
(
1
)
35
-
44
2013.06（ ISSN:0030-6096
）
-
YT-4-1(YRA) 胃癌幹細胞関連蛋白の同定と臨床的意義(YT Young Researcher Award & Traveler's Grant,第113回日本外科学会定期学術集会)
Reviewed
森崎 珠実, 八代 正和, 渡邊 真央, 大北 仁裕, 福岡 達成, 長谷川 毅, 吉井 真美, 櫻井 克宣, 久保 尚士, 田中 浩明, 六車 一哉, 大平 雅一, 梯 アンナ, 鰐渕 英機, 平川 弘聖
一般社団法人日本外科学会 日本外科学会雑誌
114
(
2
)
2013.03（ ISSN:18801129
）
-
Complexin-2 (CPLX2) as a potential prognostic biomarker in human lung high grade neuroendocrine tumors
Reviewed
Komatsu Hiroaki, Kakehashi Anna, Nishiyama Noritoshi, Izumi Nobuhiro, Mizuguchi Shinjiro, Yamano Shotaro, Inoue Hidetoshi, Hanada Shoji, Chung Kyukwang, Wei Min, Suehiro Shigefumi, Wanibuchi Hideki
CANCER BIOMARKERS
13
(
3
)
171
-
180
2013（ ISSN:1574-0153
）
-
Myristoylated alanine-rich C-kinase substrate as a prognostic biomarker in human primary lung squamous cell carcinoma
Reviewed
Hanada Shoji, Kakehashi Anna, Nishiyama Noritoshi, Wei Min, Yamano Shotaro, Chung Kyukwang, Komatsu Hiroaki, Inoue Hidetoshi, Suehiro Shigefumi, Wanibuchi Hideki
CANCER BIOMARKERS
13
(
4
)
289
-
298
2013（ ISSN:1574-0153
）
-
Evaluation of the Modifying Effect of Inhalation of Mainstream Cigarette Smoke on Mouse Bladder Carcinogenesis
Reviewed
Kato Minoru, Wei Min, Yamano Shotaro, Fujioka Masaki, Kakehashi Anna, Wanibuchi Hideki
日本毒性病理学会 JOURNAL OF TOXICOLOGIC PATHOLOGY
26
(
4
)
447
-
451
2013（ ISSN:0914-9198
）
-
Dammar resin, a non-mutagen, induces oxidative stress and metabolic enzymes in the liver of gpt delta transgenic mouse which is different from a mutagen, 2-amino-3-methylimidazo[4,5-f]quinoline (vol 748, pg 29, 2012)
Reviewed
Xie Xiao-Li, Wei Min, Kakehashi Anna, Yamano Shotaro, Okabe Kyoko, Tajiri Masaki, Wanibuchi Hideki
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
749
(
1-2
)
105
-
105
2012.12（ ISSN:1383-5718
）
-
Threshold for Genotoxic Carcinogens : The Central Concern in Carcinogenic Risk Assessment
Reviewed
Fukushima Shoji, Wei Min, Kakehashi Anna, WANIBUCHI Hideki
日本環境変異原学会 Genes and environment : the official journal of the Japanese Environmental Mutagen Society
34
(
4
)
153
-
156
2012.11（ ISSN:18807046
）
-
Long-term treatment with L-isoleucine or L-leucine in AIN-93G diet has promoting effects on rat bladder carcinogenesis
Reviewed
Xie Xiao-Li, Wei Min, Yunoki Takayuki, Kakehashi Anna, Yamano Shotaro, Kato Minoru, Wanibuchi Hideki
FOOD AND CHEMICAL TOXICOLOGY
50
(
11
)
3934
-
3940
2012.11（ ISSN:0278-6915
）
-
Dammar resin, a non-mutagen, inducts oxidative stress and metabolic enzymes in the liver of gpt delta transgenic mouse which is different from a mutagen, 2-amino-3-methylimidazo[4,5-f]quinoline
Reviewed
Xie Xiao-Li, Wei Min, Kakehashi Anna, Yamano Shotaro, Okabe Kyoko, Tajiri Masaki, Wanibuchi Hideki
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
748
(
1-2
)
29
-
35
2012.10（ ISSN:1383-5718
）
-
ラットにおける低用量の2-amino-3,8-dimethylimidazo[4,5-f]quinoxalineとdiethylnitrosamineの混合による肝発癌性の欠如 遺伝毒性発癌物質に対する閾値の存在に関する示唆(Lack of Hepatocarcinogenicity of Combinations of Low Doses of 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline and Diethylnitrosamine in Rats: Indication for the Existence of a Threshold for Genotoxic Carcinogens)
Reviewed
Wei Min, Kakehashi Anna, Yamano Shotaro, Tamano Seiko, Shirai Tomoyuki, Wanibuchi Hideki, Fukushima Shoji
日本毒性病理学会 Journal of Toxicologic Pathology
25
(
3
)
209
-
214
2012.09（ ISSN:0914-9198
）
-
Methionine Sulfoxide Stimulates Hepatocarcinogenesis in Non-alcoholic Steatohepatitis (NASH) Mouse : Possible Role of Free Radical-mediated DNA Methylation
Reviewed
Kawai Kazuaki, Li Yun-Shan, Song Ming-Fen, OOTSUYAMA Yuko, KAKEHASHI Anna, WANIBUCHI Hideki, OOTSUYAMA Akira, NORIMURA Toshiyuki, KASAI Hiroshi
日本環境変異原学会 Genes and environment : the official journal of the Japanese Environmental Mutagen Society
34
(
3
)
123
-
128
2012.08（ ISSN:18807046
）
-
DDX39 acts as a suppressor of invasion for bladder cancer
Reviewed
Kato Minoru, Wei Min, Yamano Shotaro, Kakehashi Anna, Tamada Satoshi, Nakatani Tatsuya, Wanibuchi Hideki
CANCER SCIENCE
103
(
7
)
1363
-
1369
2012.07（ ISSN:1349-7006
）
-
AGR2 as a Potential Biomarker of Human Lung Adenocarcinoma
Reviewed
Chung Kyukwang, Nishiyama Noritoshi, Wanibuchi Hideki, Yamano Shotaro, Hanada Shoji, Wei Min, Suehiro Shigefumi, Kakehashi Anna
大阪市立大学 Osaka City Medical journal
58
(
1
)
13
-
24
2012.06（ ISSN:00306096
）
-
ヒト肺腺癌のバイオマーカーとなり得るAGR2(AGR2 as a Potential Biomarker of Human Lung Adenocarcinoma)
Reviewed
Chung Kyukwang, Nishiyama Noritoshi, Wanibuchi Hideki, Yamano Shotaro, Hanada Shoji, Wei Min, Suehiro Shigefumi, Kakehashi Anna
大阪市医学会 Osaka City Medical Journal
58
(
1
)
13
-
24
2012.06（ ISSN:0030-6096
）
-
AGR2 as a potential biomarker of human lung adenocarcinoma.
Reviewed
Chung K, Nishiyama N, Wanibuchi H, Yamano S, Hanada S, Wei M, Suehiro S, Kakehashi A
Osaka city medical journal
58
(
1
)
13
-
24
2012.06（ ISSN:0030-6096
）
-
Proteome analysis of laser microdissected glomeruli from formalin-fixed paraffin-embedded kidneys of autopsies of diabetic patients: nephronectin is associated with the development of diabetic glomerulosclerosis
Reviewed
Nakatani Shinya, Wei Min, Ishimura Eiji, Kakehashi Anna, Mori Katsuhito, Nishizawa Yoshiki, Inaba Masaaki, Wanibuchi Hideki
NEPHROLOGY DIALYSIS TRANSPLANTATION
27
(
5
)
1889
-
1897
2012.05（ ISSN:0931-0509
）
-
Comparison proteome analysis of scirrhous gastric carcinoma stem cell-like SP and hypoxia-resistant cell lines
Reviewed
Morisaki Tamami, Yashiro Masakazu, Kakehashi Anna, Okita Yoshihiro, Fukuoka Tatsunari, Aomatsu Naoki, Yoshii Mami, Hasegawa Tsuyoshi, Matsuoka Junko, Nagahara Hisashi, Kimura Kenjiro, Noda Eiji, Amano Ryosuke, Kubo Naoshi, Tanaka Hiroaki, Muguruma Kazuya, Yamada Nobuya, Maeda Kiyoshi, Nakata Bunzo, Ohira Masaichi, Wanibuchi Hideki, Hirakawa Kosei
CANCER RESEARCH
72
2012.04（ ISSN:0008-5472
）
-
Hormonally Active Doses of Isoflavone Aglycones Promote Mammary and Endometrial Carcinogenesis and Alter the Molecular Tumor Environment in Donryu Rats
Reviewed
Kakehashi Anna, Tago Yoshiyuki, Yoshida Midori, Sokuza Yui, Wei Min, Fukushima Shoji, Wanibuchi Hideki
TOXICOLOGICAL SCIENCES
126
(
1
)
39
-
51
2012.03（ ISSN:1096-6080
）
-
2-Amino-3-Methylimidazo[4,5-f]Quinoline (IQ) Promotes Mouse Hepatocarcinogenesis by Activating Transforming Growth Factor-beta and Wnt/beta-Catenin Signaling Pathways
Reviewed
Xie Xiao-Li, Wei Min, Kakehashi Anna, Yamano Shotaro, Tajiri Masaki, Wanibuchi Hideki
TOXICOLOGICAL SCIENCES
125
(
2
)
392
-
400
2012.02（ ISSN:1096-6080
）
-
Lack of Hepatocarcinogenicity of Combinations of Low Doses of 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline and Diethylnitrosamine in Rats: Indication for the Existence of a Threshold for Genotoxic Carcinogens
Reviewed
Wei Min, Kakehashi Anna, Yamano Shotaro, Tamano Seiko, Shirai Tomoyuki, Wanibuchi Hideki, Fukushima Shoji
日本毒性病理学会 JOURNAL OF TOXICOLOGIC PATHOLOGY
25
(
3
)
209
-
214
2012（ ISSN:0914-9198
）
-
Low-dose carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in rats: Evidence for the existence of no-effect levels and a mechanism involving p21(Cip/WAF1)
Reviewed
Wei Min, Kakehashi Anna, Yamano Shotaro, Fukushima Shoji, Wanibuchi Hideki
CANCER RESEARCH
71
2011.04（ ISSN:0008-5472
）
-
Enhanced Urinary Bladder, Liver and Colon Carcinogenesis in Zucker Diabetic Fatty Rats in a Multiorgan Carcinogenesis Bioassay : Evidence for Mechanisms Involving Activation of PI3K Signaling and Impairment of p53 on Urinary Bladder Carcinogenesis
Reviewed
ISHII Naomi, WEI Min, KAKEHASHI Anna, DOI Kenichiro, YAMANO Shotaro, INABA Masaaki, WANIBUCHI Hideki
Journal of toxicologic pathology
24
(
1
)
25
-
36
2011.03（ ISSN:09149198
）
-
Tumor-associated MUC5AC stimulates in vivo tumorigenicity of human pancreatic cancer
Reviewed
Hoshi Hirotaka, Sawada Tetsuji, Uchida Motoyuki, Saito Hikaru, Iijima Hiroko, Toda-Agetsuma Mikako, Wada Tsutomu, Yamazoe Sadaaki, Tanaka Hiroaki, Kimura Kenjiro, Kakehashi Anna, Wei Min, Hirakawa Kosei, Wanibuchi Hideki
INTERNATIONAL JOURNAL OF ONCOLOGY
38
(
3
)
619
-
627
2011.03（ ISSN:1019-6439
）
-
Non-genotoxic mode of action and possible threshold for hepatocarcinogenicity of Kojic acid in F344 rats
Reviewed
Chusiri Yaowares, Wongpoomchai Rawiwan, Kakehashi Anna, Wei Min, Wanibuchi Hideki, Vinitketkumnuan Usanee, Fukushima Shoji
FOOD AND CHEMICAL TOXICOLOGY
49
(
2
)
471
-
476
2011.02（ ISSN:0278-6915
）
-
Mitochondrial Prohibitins and Septin 9 Are Implicated in the Onset of Rat Hepatocarcinogenesis
Reviewed
Kakehashi Anna, Ishii Naomi, Shibata Takeshi, Wei Min, Okazaki Etsuko, Tachibana Taro, Fukushima Shoji, Wanibuchi Hideki
TOXICOLOGICAL SCIENCES
119
(
1
)
61
-
72
2011.01（ ISSN:1096-6080
）
-
Existence of a threshold for genotoxic carcinogens
Reviewed
WEI MIN, KAKEHASHI ANNA, FUKUSHIMA SHOJI, WANIBUCHI HIDEKI
The Japanese Society of Toxicology, Annual Meeting of the Japanese Society of Toxicology
38
(
0
)
184
-
184
2011
-
Enhanced Urinary Bladder, Liver and Colon Carcinogenesis in Zucker Diabetic Fatty Rats in a Multiorgan Carcinogenesis Bioassay: Evidence for Mechanisms Involving Activation of PI3K Signaling and Impairment of p53 on Urinary Bladder Carcinogenesis
Reviewed
Ishii Naomi, Wei Min, Kakehashi Anna, Doi Kenichiro, Yamano Shotaro, Inaba Masaaki, Wanibuchi Hideki
日本毒性病理学会 JOURNAL OF TOXICOLOGIC PATHOLOGY
24
(
1
)
25
-
35
2011（ ISSN:0914-9198
）
-
Targeted Proteomics of Isolated Glomeruli from the Kidneys of Diabetic Rats: Sorbin and SH3 Domain Containing 2 Is a Novel Protein Associated with Diabetic Nephropathy
Reviewed
Nakatani Shinya, Kakehashi Anna, Ishimura Eiji, Yamano Shotaro, Mori Katsuhito, Wei Min, Inaba Masaaki, Wanibuchi Hideki
EXPERIMENTAL DIABETES RESEARCH
2011
979354
2011（ ISSN:1687-5214
）
-
Serum AGR2 as an early diagnostic and postoperative prognostic biomarker of human lung adenocarcinoma
Reviewed
Chung Kyukwang, Nishiyama Noritoshi, Yamano Shotaro, Komatsu Hiroaki, Hanada Shoji, Wei Min, Wanibuchi Hideki, Suehiro Shigefumi, Kakehashi Anna
CANCER BIOMARKERS
10
(
2
)
101
-
107
2011（ ISSN:1574-0153
）
-
Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats.
Reviewed
Tago Y, Wei M, Ishii N, Kakehashi A, Wanibuchi H
日本毒性病理学会 Journal of toxicologic pathology
23
(
4
)
245
-
51
2010.12（ ISSN:0914-9198
）
-
F344ラットにおける食餌中投与されたEquisetum arvenseの亜慢性毒性の評価(Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats)
Reviewed
Tago Yoshiyuki, Wei Min, Ishii Naomi, Kakehashi Anna, Wanibuchi Hideki
日本毒性病理学会 Journal of Toxicologic Pathology
23
(
4
)
245
-
251
2010.12（ ISSN:0914-9198
）
-
Rat Monoclonal Antibody Specific for Septin 9
Reviewed
Tachibana Taro, Okazaki Etsuko, Yoshimi Tomohiko, Azuma Masayuki, Kakehashi Anna, Wanibuchi Hideki
HYBRIDOMA
29
(
2
)
169
-
171
2010.04（ ISSN:1554-0014
）
-
Cytokeratin 8/18 as a new marker of mouse liver preneoplastic lesions
Reviewed
Kakehashi Anna, Kato Ayumi, Inoue Masayo, Ishii Naomi, Okazaki Etsuko, Wei Min, Tachibana Taro, Wanibuchi Hideki
TOXICOLOGY AND APPLIED PHARMACOLOGY
242
(
1
)
47
-
55
2010.01（ ISSN:0041-008X
）
-
Sensitive quantitative assay for point mutations in the rat H-ras gene based on single nucleotide primer extension
Reviewed
Yano Yoshihisa, Yano Tomohiro, Kinoshita Anna, Matoba Ai, Hasuma Tadayoshi, Wanibuchi Hideki, Morimura Keiichirou, Otani Shuzo, Fukushima Shoji
EXPERIMENTAL AND THERAPEUTIC MEDICINE
1
(
4
)
657
-
661
2010（ ISSN:1792-0981
）
-
Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats
Reviewed
Tago Yoshiyuki, Wei Min, Ishii Naomi, Kakehashi Anna, Wanibuchi Hideki
JOURNAL OF TOXICOLOGIC PATHOLOGY
23
(
4
)
245
-
251
2010（ ISSN:0914-9198
）
-
Characteristic upregulation of glucose-regulated protein 78 in an early lesion negative for hitherto established cytochemical markers in rat hepatocarcinogenesis.
Reviewed
Sukata T, Uwagawa S, Ozaki K, Sumida K, Kushida M, Kakehashi A, Wanibuchi H, Miyata K, Ogata K, Fukushima S
日本毒性病理学会 Journal of toxicologic pathology
22
(
4
)
281
-
8
2009.12（ ISSN:0914-9198
）
-
Potassium Bromate Enhances N-Ethyl-N-Hydroxyethylnitrosamine-Induced Kidney Carcinogenesis Only at High Doses in Wistar Rats: Indication of the Existence of an Enhancement Threshold
Reviewed
Wei Min, Hamoud Al-Salmy, Yamaguchi Takashi, Kakehashi Anna, Marimura Keiichirou, Doi Kenichiro, Kushida Masahiko, Kitano Mitsuaki, Wanibuchi Hideki, Fukushima Shoji
TOXICOLOGIC PATHOLOGY
37
(
7
)
983
-
991
2009.12（ ISSN:0192-6233
）
-
Urinary bladder carcinogenesis induced by chronic exposure to persistent low-dose ionizing radiation after Chernobyl accident
Reviewed
Romanenko Alina, Kakehashi Anna, Morimura Keiichirou, Wanibuchi Hideki, Wei Min, Vozianov Alexander, Fukushima Shoji
CARCINOGENESIS
30
(
11
)
1821
-
1831
2009.11（ ISSN:0143-3334
）
-
Cytokeratin 8/18 overexpression and complex formation as an indicator of GST-P positive foci transformation into hepatocellular carcinomas
Reviewed
Kakehashi Anna, Inoue Masayo, Wei Min, Fukushima Shoji, Wanibuchi Hideki
TOXICOLOGY AND APPLIED PHARMACOLOGY
238
(
1
)
71
-
79
2009.07（ ISSN:0041-008X
）
-
Existence of a Threshold for the Genotoxic Carcinogens : Evidence from Mechanism-based Carcinogenicity Studies
Reviewed
Fukushima Shoji, Kakehashi Anna, Wei Min, WANIBUCHI Hideki
日本環境変異原学会 Genes and environment : the official journal of the Japanese Environmental Mutagen Society
31
(
2
)
33
-
36
2009.05（ ISSN:18807046
）
-
Ethanol Does Not Promote MeIQx-initiated Rat Colon Carcinogenesis Based on Evidence from Analysis of a Colon Cancer Surrogate Marker.
Reviewed
Kushida M, Wanibuchi H, Wei M, Kakehashi A, Ozaki K, Sukata T, Miyata K, Ogata K, Uwagawa S, Fukushima S
日本毒性病理学会 Journal of toxicologic pathology
22
(
1
)
65
-
70
2009.03（ ISSN:0914-9198
）
-
Characteristic Upregulation of Glucose-Regulated Protein 78 in an Early Lesion Negative for Hitherto Established Cytochemical Markers in Rat Hepatocarcinogenesis
Reviewed
Sukata Tokuo, Uwagawa Satoshi, Ozaki Keisuke, Sumida Kayo, Kushida Masahiko, Kakehashi Anna, Wanibuchi Hideki, Miyata Kaori, Ogata Keiko, Fukushima Shoji
JOURNAL OF TOXICOLOGIC PATHOLOGY
22
(
4
)
281
-
288
2009（ ISSN:0914-9198
）
-
Ethanol Does Not Promote MeIQx-initiated Rat Colon Carcinogenesis Based on Evidence from Analysis of a Colon Cancer Surrogate Marker
Reviewed
Kushida Masahiko, Wanibuchi Hideki, Wei Min, Kakehashi Anna, Ozaki Keisuke, Sukata Tokuo, Miyata Kaori, Ogata Keiko, Uwagawa Satoshi, Fukushima Shoji
JOURNAL OF TOXICOLOGIC PATHOLOGY
22
(
1
)
65
-
70
2009（ ISSN:0914-9198
）
-
Are there thresholds for carcinogens carcinogenicity?
Reviewed
FUKUSHIMA Shoji, WEI Min, KAKEHASHI Anna, WANIBUCHI Hideki
Japanese Society of Mycotoxicology, JSM Mycotoxins
58
(
2
)
119
-
128
2008.07（ ISSN:02851466
）
-
Chemopreventive effects of a serratane-type triterpenoid, 3 alpha-methoxyserrat-14-en-21 beta-ol (PJ-1), against rat lung carcinogenesis
Reviewed
Yamaguchi Chiharu, Wanibuchi Hideki, Kakehashi Anna, Tanaka Reiko, Fukushima Shoji
FOOD AND CHEMICAL TOXICOLOGY
46
(
6
)
1882
-
1888
2008.06（ ISSN:0278-6915
）
-
食品などに含まれる発がん物質に閾値が存在するのか
Reviewed
梯 アンナ
食衛誌 49
2008
-
Elevation of 8-hydroxydeoxyguanosine and cell proliferation via generation of oxidative stress by organic arsenicals contributes to their carcinogenicity in the rat liver and bladder
Reviewed
Kinoshita Anna, Wanibuchi Hideki, Wei Min, Yunokl Takayuki, Fukushima Shoji
TOXICOLOGY AND APPLIED PHARMACOLOGY
221
(
3
)
295
-
305
2007.06（ ISSN:0041-008X
）
-
Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice
Reviewed
Kinoshita Anna, Wanibuchi Hideki, Morimura Keiichirou, Wei Min, Nakae Dai, Arai Tsuyoshi, Minowa Osamu, Noda Tetsuo, Nishimura Susumu, Fukushima Shoji
CANCER SCIENCE
98
(
6
)
803
-
814
2007.06（ ISSN:1347-9032
）
-
Analysis of gene expression in different stages of MeIQx-induced rat hepatocarcinogenesis
Reviewed
Kang Jin Seok, Wanibuchi Hideki, Murai Takashi, Morimura Keiichirou, Kinoshita Anna, Fukushima Shoji
ONCOLOGY REPORTS
17
(
4
)
747
-
752
2007.04（ ISSN:1021-335X
）
-
Evaluation of the toxicity of mastic gum with 13 weeks dietary administration to F344 rats
Reviewed
Kang Jin Seok, Wanibuchi Hideki, Salim Elsayed I., Kinoshita Anna, Fukushima Shoji
FOOD AND CHEMICAL TOXICOLOGY
45
(
3
)
494
-
501
2007.03（ ISSN:0278-6915
）
-
Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice
Cancer Science
98
(
6
)
803
-
814
2007
-
Elevation of 8-hydroxydeoxyguanosine and cell proliferation via generation of oxidative stress by organic arsenicals contributes to their carcinogenicity in the rat liver and bladder
Toxicol Appl Pharmacol
221
(
3
)
295
-
305
2007
-
Upregulation of fibroblast growth factor receptor 3 and epidermal growth factor receptors, in association with Raf-1, in urothelial dysplasia and carcinoma in situ after the Chernobyl accident
Reviewed
Romanenko Alina M., Morimura Keiichirou, Kinoshita Anna, Wanibuchi Hideki, Takahashi Satoru, Zaparin Wadim K., Vinnichenko Wladimir I., Vozianov Alexander F., Fukushima Shoji
CANCER SCIENCE
97
(
11
)
1168
-
1174
2006.11（ ISSN:1349-7006
）
-
Hormesis in Carcinogenicity of Non-genotoxic Carcinogens
Reviewed
KINOSHITA Anna, WANIBUCHI Hideki, WEI Min, FUKUSHIMA Shoji
日本毒性病理学会 Journal of toxicologic pathology
19
(
3
)
111
-
122
2006.09（ ISSN:0914-9198
）
-
Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes
Reviewed
Puatanachokchai Rawiwan, Morimura Keiichirou, Wanibuchi Hideki, Oka Mayuko, Kinoshita Anna, Mitsuru Fukui, Yamaguchi Shuji, Funae Yoshihiko, Fukushima Shoji
CANCER LETTERS
240
(
1
)
102
-
113
2006.08（ ISSN:0304-3835
）
-
N-acetylcysteine and S-methylcysteine inhibit MeIQx rat hepatocarcinogenesis in the post-initiation stage
Reviewed
Nishikawa-Ogawa M, Wanibuchi H, Morimura K, Kinoshita A, Nishikawa T, Hayashi S, Yano Y, Fukushima S
CARCINOGENESIS
27
(
5
)
982
-
988
2006.05（ ISSN:0143-3334
）
-
Lack of promoting effects of phenobarbital at low dose on diethylnitrosamine-induced hepatocarcinogenesis in TGF-alpha transgenic mice.
Reviewed
Puatanachokchai R, Kakuni M, Wanibuchi H, Kinoshita A, Kang JS, Salim EI, Morimura K, Tamano S, Merlino GT, Fukushima S
Asian Pacific journal of cancer prevention : APJCP
7
(
2
)
274
-
8
2006.04（ ISSN:1513-7368
）
-
A comparative study of the sub-chronic toxic effects of three organic arsenical compounds on the urothelium in F344 rats; gender-based differences in response
Reviewed
Shen J, Wanibuchi H, Waalkes MP, Salim EI, Kinoshita A, Yoshida K, Endo G, Fukushima S
TOXICOLOGY AND APPLIED PHARMACOLOGY
210
(
3
)
171
-
180
2006.02（ ISSN:0041-008X
）
-
Involvement of ubiquitination and sumoylation in bladder lesions induced by persistent long-term low dose ionizing radiation in humans
Reviewed
Romanenko AM, Kinoshita A, Wanibuchi H, Wei M, Zaparin WK, Vinnichenko WI, Vozianov AF, Fukushima S
JOURNAL OF UROLOGY
175
(
2
)
739
-
743
2006.02（ ISSN:0022-5347
）
-
Aberrant expression of E-cadherin and beta-catenin in association with transforming growth factor-beta 1 in urinary bladder lesions in humans after the Chernobyl accident
Reviewed
Romanenko A, Morimura K, Kinoshita A, Wanibuchi H, Vozianov A, Fukushima S
CANCER SCIENCE
97
(
1
)
45
-
50
2006.01（ ISSN:1347-9032
）
-
Inhibition of rat urinary bladder carcinogenesis by the antiangiogenic drug TNP-470.
Reviewed
Wanibuchi H, Wei M, Salim EI, Kinoshita A, Morimura K, Sudo K, Fukushima S
Asian Pacific journal of cancer prevention : APJCP
7
(
1
)
101
-
7
2006.01（ ISSN:1513-7368
）
-
Effects of cessation of alcohol exposure on rat hepatocarcinogenesis.
Reviewed
Wanibuchi H, Zhang Y, Kinoshita A, Wei M, Kang JS, Fukushima S
Asian Pacific journal of cancer prevention : APJCP
7
(
1
)
122
-
6
2006.01（ ISSN:1513-7368
）
-
Involvement of ubiquitination and sumoylation in bladder lesions induced by persistent long-term low dose ionizing radiation in humans.
J. Urology
175
(
2
)
739
-
743
2006
-
Existence of no hepatocarcinogenic effect levels of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline with or without coadministration with ethanol
Reviewed
Wanibuchi Hideki, Wei Min, Karim M. Rezaul, Morimura Keiichirou, Doi Kenichiro, Kinoshita Anna, Fukushima Shoji
TOXICOLOGIC PATHOLOGY
34
(
3
)
232
-
236
2006（ ISSN:0192-6233
）
-
Upregulation of fibroblast growth factor receptor 3 and epidermal growth factor receptors, in association with Raf-1, in urothelial dysplasia and carcinoma in situ after the Chernobyl accident.
97
1168
-
1174
2006
-
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: Possible mechanisms
Reviewed
Kushida M, Sukata T, Uwagawa S, Ozaki K, Kinoshita A, Wanibuchi H, Morimura K, Okuno Y, Fukushima S
TOXICOLOGY AND APPLIED PHARMACOLOGY
208
(
3
)
285
-
294
2005.11（ ISSN:0041-008X
）
-
Dose-dependence of promotion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis by ethanol: Evidence for a threshold
Reviewed
Kushida M, Wanibuchi H, Morimura K, Kinoshita A, Kang JS, Puatanachokchai R, Wei M, Funae Y, Fukushima S
CANCER SCIENCE
96
(
11
)
747
-
757
2005.11（ ISSN:1349-7006
）
-
Hormesis and dose-response-mediated mechanisms in carcinogenesis: evidence for a threshold in carcinogenicity of non-genotoxic carcinogens
Reviewed
Fukushima S, Kinoshita A, Puatanachokchai R, Kushida M, Wanibuchi H, Morimura K
CARCINOGENESIS
26
(
11
)
1835
-
1845
2005.11（ ISSN:0143-3334
）
-
Current and emerging challenges in toxicopathology: carcinogenic threshold of phenobarbital and proof of arsenic carcinogenicity using rat medium-term bioassays for carcinogens.
Reviewed
Fukushima S, Morimura K, Wanibuchi H, Kinoshita A, Salim EI
Toxicology and applied pharmacology
207
(
2 Suppl
)
225
-
9
2005.09（ ISSN:0041-008X
）
-
Lack of large intestinal carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine at low doses in rats initiated with azoxymethane
Reviewed
Doi K, Wanibuchi H, Salim EI, Morimura K, Kinoshita A, Kudoh S, Hirata K, Yoshikawa J, Fukushima S
INTERNATIONAL JOURNAL OF CANCER
115
(
6
)
870
-
878
2005.07（ ISSN:0020-7136
）
-
Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes.
240
(
1
)
102
-
113
2005
-
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: possible mechanisms
208
(
3
)
285
-
294
2005
-
Understanding arsenic carcinogenicity by the use of animal models
Reviewed
Wanibuchi H, Salim EI, Kinoshita A, Shen J, Wei M, Morimura K, Yoshida K, Kuroda K, Endo G, Fukushima S
TOXICOLOGY AND APPLIED PHARMACOLOGY
198
(
3
)
366
-
376
2004.08（ ISSN:0041-008X
）
-
Possible distinct molecular carcinogenic pathways for bladder cancer in Ukraine, before and after the Chernobyl disaster
Reviewed
Morimura K, Romanenko A, Min W, Salim EI, Kinoshita A, Wanibuchi H, Vozianov A, Fukushima S
ONCOLOGY REPORTS
11
(
4
)
881
-
886
2004.04（ ISSN:1021-335X
）
-
Lack of preventive efficacy of FK228, a histone deacetylase inhibitor, against N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder carcinogenesis in P53(+/-) and P53(+/+) mice
Reviewed
Wei M, Wanibuchi H, Morimura K, Salim EI, Moku M, Doi K, Mitsuhashi M, Masuda C, Shen J, Kinoshita A, Fukushima S
ANTICANCER RESEARCH
24
(
2B
)
785
-
790
2004（ ISSN:0250-7005
）
-
Liver tumorigenicity of trimethylarsine oxide in male Fischer 344 rats-association with oxidative DNA damage and enhanced cell proliferation
Reviewed
Shen J, Wanibuchi H, Salim EI, Wei M, Kinoshita A, Yoshida K, Endo G, Fukushima S
CARCINOGENESIS
24
(
11
)
1827
-
1835
2003.11（ ISSN:0143-3334
）
-
Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression
Reviewed
Kinoshita A, Wanibuchi H, Morimura K, Wei M, Shen J, Imaoka S, Funae Y, Fukushima S
CARCINOGENESIS
24
(
8
)
1389
-
1399
2003.08（ ISSN:0143-3334
）
-
High susceptibility of p53 knockout mice to esophageal and urinary bladder carcinogenesis induced by N,N-dibutylnitrosamine
Reviewed
Nishikawa T, Salim EI, Morimura K, Kaneko M, Ogawa M, Kinoshita A, Osugi H, Kinoshita H, Fukushima S
CANCER LETTERS
194
(
1
)
45
-
54
2003.05（ ISSN:0304-3835
）
-
Urinary bladder lesions induced by persistent chronic low-dose ionizing radiation
Reviewed
Romanenko A, Morimura K, Wanibuchi H, Wei M, Zaparin W, Vinnichenko W, Kinoshita A, Vozianov A, Fukushima S
CANCER SCIENCE
94
(
4
)
328
-
333
2003.04（ ISSN:1347-9032
）
-
Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: A possible reactive oxygen species mechanism
Reviewed
Nishikawa T, Wanibuchi H, Ogawa M, Kinoshita A, Morimura K, Hiroi T, Funae Y, Kishida H, Nakae D, Fukushima S
INTERNATIONAL JOURNAL OF CANCER
100
(
2
)
136
-
139
2002.07（ ISSN:0020-7136
）
-
Detailed low-dose study of 1,1-b is(p-chlorophenyl)-2,2,2-trichloroethane carcinogenesis suggests the possibility of a hormetic effect
Reviewed
Sukata T, Uwagawa S, Ozaki K, Ogawa M, Nishikawa T, Iwai S, Kinoshita A, Wanibuchi H, Imaoka S, Funae Y, Okuno Y, Fukushima S
INTERNATIONAL JOURNAL OF CANCER
99
(
1
)
112
-
118
2002.05（ ISSN:0020-7136
）
-
Formation of 8-hydroxydeoxyguanosine and cell-cycle arrest in the rat liver via generation of oxidative stress by phenobarbital: association with expression profiles of p21(WAF1/Cip1), cyclin D1 and Ogg1
Reviewed
Kinoshita A, Wanibuchi H, Imaoka S, Ogawa M, Masuda C, Morimura K, Funae Y, Fukushima S
CARCINOGENESIS
23
(
2
)
341
-
349
2002.02（ ISSN:0143-3334
）
-
Increased oxidative stress with gene alteration in urinary bladder urothelium after the Chernobyl accident
Reviewed
Romanenko A, Morimura K, Wanibuchi H, Salim EI, Kinoshita A, Kaneko M, Vozianov A, Fukushima S
INTERNATIONAL JOURNAL OF CANCER
86
(
6
)
790
-
798
2000.06（ ISSN:0020-7136
）
-
Biochemical markers of fetal brain developmental disturbances
Reviewed
Arutjunyan A.V., Pavlova N.G., Konstantinova N.N., Pavlenko A.V. (Kakehashi A.), Kashcheeva T.K., Kozina L.S., Kasheeva T.K.
International Journal of Developmental Neuroscience
14
108
-
108
1996
-
Biochemical markers of brain development disorders
Reviewed
Arutjunyan A.V., Pavlova N.G., Konstantinova N.N., Pavlenko A.V. (Kakehashi A.), Kashcheeva T.K.,Lyzlova L.V., Kozina L.S., Rusina E.I., Mikhailov A.V., Shelaeva E.V.
Neurochemistry
13
(
3
)
187
-
193
1996
