Updated on 2024/02/01

写真a

 
YOSHIDA Kayo
 
Organization
Graduate School of Medicine Department of Basic Medical Science Associate Professor
School of Medicine Department of Medical Science
Title
Associate Professor
Affiliation
Institute of Medicine
Affiliation campus
Abeno Campus

Position

  • Graduate School of Medicine Department of Basic Medical Science 

    Associate Professor  2022.04 - Now

  • School of Medicine Department of Medical Science 

    Associate Professor  2022.04 - Now

Degree

  • 医学博士 ( Osaka University )

  • Master of Pharmaceutical Science ( Osaka University )

Research Areas

  • Life Science / Molecular biology  / Molecular Biology

Research Interests

  • DNA損傷、相同組換え、修復、染色体異常

Research Career

  • Study on Homologous Recombination Genes in mammals

    Homologous Recombination, Rad51 Gene, Dmc1 Gene  Individual

    1996.04 - Now 

Professional Memberships

  • 日本分子生物学会

      Domestic

  • 日本実験動物学会

      Domestic

Awards

  • ICRR2015 Excellent Poster Award

    Takashi Morita, Kayo Yoshida, Akane Kizu, Kouhei Kitada, Megumi Hada, Kiyomi Kasai, Takeshi Teramura, Hiromi Suzuki, Toru Shimazu, Sachiko Yano, Masaki Shirakawa, Ikuko Osada, Haruo Kasahara, Francis. A. Cucinotta

    2015.05   15th International Congress of Radiation Research   The Space Experiment Project (Stem Cells) in International Space Station to Evaluate Effects of Space Radiation Using Mouse ES Cells

Education

  • Osaka University   Master's Course   Graduated/Completed

    - 1998

Papers

  • Comparison of biological measurement and physical estimates of space radiation in the International Space Station. Reviewed International coauthorship

    Yoshida K, Hada M, Kizu A, Kitada K, Eguchi-Kasai K, Kokubo T, Teramura T, Yano S, Suzuki HH, Watanabe H, Kondoh G, Nagamatsu A, Saganti P, Cucinotta FA, Morita T

    Heliyon   8 ( 8 )   e10266   2022.08( ISSN:2405-8440

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    Authorship:Lead author   International / domestic magazine:International journal  

    DOI: 10.1016/j.heliyon.2022.e10266

    PubMed

  • Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle Reviewed

    Takada N, Takasugi M, Nonaka Y, Kamiya T, Takemura K, Satoh J, Ito S, Fujimoto K, Uematsu S, Yoshida K, Morita T, Nakamura H, Uezumi A, Ohtani N

    Development   149 ( 3 )   2022.02( ISSN:0950-1991

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    International / domestic magazine:International journal  

    DOI: 10.1242/dev.199443

  • Upregulation of PTK7 and β-catenin after vaginal mechanical dilatation: an examination of fiblin-5 knockout mice Reviewed International coauthorship

    R. Uemura, D. Tachibana, M. Shiota, K. Yoshida, K. Kitada, A. Hamuro, T. Misugi, M. Koyama

    International Urogynecology Journal   2021.02

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

    DOI: 10.1007//s00192-021-04693-2.

  • Enhanced homologous recombination by the modulation of targeting vector ends. Reviewed International coauthorship

    S. Hirotsune, H. Kiyonari, M. Jin, K. Kumamoto, K. Yoshida, M. Shinohara, H. Watanabe, A. Wynshaw-Boris, F. Matsuzaki

    Scientific Reports   10 ( 1 )   2020.02

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Low-dose irradiation of mouse embryos increases Smad-p21 pathway activity and preserves pluripotency. Reviewed

    Hayashi M, Yoshida K, Kitada K, Kizu A, Tachibana D, Fukui M, Morita T, Koyama M

    Journal of assisted reproduction and genetics   2018.03( ISSN:1058-0468

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10815-018-1156-y

    PubMed

  • Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice Reviewed

    Umeda Tomohiro, Kimura Tetsuya, Yoshida Kayo, Takao Keizo, Fujita Yuki, Matsuyama Shogo, Sakai Ayumi, Yamashita Minato, Yamashita Yuki, Ohnishi Kiyouhisa, Suzuki Mamiko, Takuma Hiroshi, Miyakawa Tsuyoshi, Takashima Akihiko, Morita Takashi, Mori Hiroshi, Tomiyama Takami

    ACTA NEUROPATHOLOGICA COMMUNICATIONS   5 ( 1 )   59   2017.07( ISSN:2051-5960

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40478-017-0461-5

    PubMed

  • Gene-modified embryonic stem cell test to characterize chemical risks Reviewed

    Kitada Kohei, Kizu Akane, Teramura Takeshi, Takehara Toshiyuki, Hayashi Masami, Tachibana Daisuke, Wanibuchi Hideki, Fukushima Shoji, Koyama Masayasu, Yoshida Kayo, Morita Takashi

    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH   22 ( 22 )   18252 - 18259   2015.11( ISSN:0944-1344

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11356-015-5051-0

    PubMed

  • ISP-19-7 The evaluation of sensitivity of mouse early embryos to X-ray irradiation by time-lapse movie(Group 19 Reproduction 2,IS Poster,International Session) : Reviewed

    Kitada Kohei, Yamamoto Hiroko, Hamuro Akihiro, Hamasaki Shin, Nakano Akemi, Terada Hiroyuki, Ozaki Koji, Kizu Akane, Tachibana Daisuke, Koyama Masayasu, Yoshida Kayo

    日本産科婦人科学会 日本産科婦人科學會雜誌   66 ( 2 )   2014( ISSN:03009165

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    Publishing type:Research paper (scientific journal)  

    CiNii Article

  • Damage-Induced Neuronal Endopeptidase Is Critical for Presynaptic Formation of Neuromuscular Junctions Reviewed

    Nagata Kenichi, Kiryu-Seo Sumiko, Maeda Mitsuyo, Yoshida Kayo, Morita Takashi, Kiyama Hiroshi

    JOURNAL OF NEUROSCIENCE   30 ( 20 )   6954 - 6962   2010.05( ISSN:0270-6474

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1523/JNEUROSCI.4521-09.2010

    PubMed

  • Study of the Effects of Space Radiation on Mouse ES cells Reviewed

    Yoshida Kayo, Yoshida Shuhei, Eguchi-Kasai Kiyomi, MORITA Takashi

    日本宇宙生物科学会 宇宙生物科学 = Biological sciences in space   24 ( 1 )   11 - 15   2010.04( ISSN:09149201

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    Publishing type:Research paper (scientific journal)  

    CiNii Article

  • Rad18 is required for long-term maintenance of spermatogenesis in mouse testes Reviewed

    Sun Jinghua, Yomogida Kentaro, Sakao Suzu, Yamamoto Haruna, Yoshida Kayo, Watanabe Kenji, Morita Takashi, Araki Kimi, Yamamura Ken-ichi, Tateishi Satoshi

    MECHANISMS OF DEVELOPMENT   126 ( 3-4 )   173 - 183   2009( ISSN:0925-4773

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.mod.2008.11.004

    PubMed

  • Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells Reviewed

    Lee Jibak, Kitajima Tomoya S., Tanno Yuji, Yoshida Kayo, Morita Takashi, Miyano Takashi, Miyake Masashi, Watanabe Yoshinori

    NATURE CELL BIOLOGY   10 ( 1 )   42 - U29   2008.01( ISSN:1465-7392

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/ncb1667

    PubMed

  • Mitochondria-related male infertility Reviewed

    Nakada Kazuto, Sato Akitsugu, Yoshida Kayo, Morita Takashi, Tanaka Hiromitsu, Inoue Shin-Ichi, Yonekawa Hiromichi, Hayashi Jun-Ichi

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   103 ( 41 )   15148 - 15153   2006.10( ISSN:0027-8424

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1073/pnas.0604641103

    PubMed

  • A histone H3 methyltransferase controls epigenetic events required for meiotic prophase Reviewed

    Hayashi K, Yoshida K, Matsui Y

    NATURE   438 ( 7066 )   374 - 378   2005.11( ISSN:0028-0836

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/nature04112

    PubMed

  • RNA interference during spermatogenesis in mice Reviewed

    Shoji M, Chuma S, Yoshida K, Morita T, Nakatsuji N

    DEVELOPMENTAL BIOLOGY   282 ( 2 )   524 - 534   2005.06( ISSN:0012-1606

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.ydbio.2005.03.030

    PubMed

  • p53 Protein interacts specifically with the meiosis-specific mammalian RecA-like protein DMC1 in meiosis.

    Carcinogenesis.   25   889 - 893   2004

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    Publishing type:Research paper (scientific journal)  

  • Control of radiosensitivity of F9 mouse teratocarcinoma cells by regulation of histone H2AX gene expression using a tetracycline turn-off system. Reviewed International coauthorship

    Cancer Res.   64   4131 - 4136   2004

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    Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Expression and Radiation-induced Phosphorylation of Histone H2AX in Mammalian Cells

    J. RADIAT. RES.   44   47 - 51   2003

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    Publishing type:Research paper (scientific journal)  

  • Easy assessment of ES cell clone potency for chimeric development and germ-line competency by an optimized aggregation method.

    J. Biochem.Biophys. Methods   39   137 - 142   1999

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    Publishing type:Research paper (scientific journal)  

  • The Mouse RecA-like Gene, Dmc1 is required for homologous chromosome synapsis during meiosis.

    Mol. Cell   1 ( 5 )   707 - 718   1998

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    Publishing type:Research paper (scientific journal)  

  • Cell cycle-dependent expression of the mouse Rad51 gene in proliferating cells.

    Mol. Gen. Genet.   251   1 - 12   1996

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    Publishing type:Research paper (scientific journal)  

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MISC

  • Rad18 is required for long-term maintenance of spermatogenesis in mouse testes.

    Mechanisms. Dev.   126   173 - 183   2009

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 【宇宙放射線が生物に与える影響(2)】 マウスのES細胞に対する宇宙放射線の影響についての研究(【Biological effects of space radiation (Part II)】 Study of the Effects of Space Radiation on Mouse ES cells) Reviewed

    Yoshida Kayo, Yoshida Shuhei, Eguchi-Kasai Kiyomi, Morita Takashi

    (一社)日本宇宙生物科学会 Biological Sciences in Space   24 ( 1 )   11 - 15   2010.04( ISSN:0914-9201

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Unified mode of centromeric protein by shugoshin in mammalian oocyte and somatic cells.

    Nature cell biology   10   42 - 52   2008

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 哺乳動物細胞の放射線感受性を抑制する -DNA修復遺伝子の発現抑制-(分担)

    吉田佳世、森田隆

    放射線生物研究   36 ( 3 )   286 - 299   2003

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 哺乳動物の遺伝子研究に活用されるRNAi

    森田隆

    共立出版、蛋白質 核酸 酵素   47 ( 14 )   1939 - 1945   2002

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    Publishing type:Article, review, commentary, editorial, etc. (other)  

  • recA/Rad51ファミリー遺伝子欠損の病態(分担)

    森田隆

    共立出版・蛋白 核酸 酵素   46 ( 8 )   1021 - 1029   2001

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 技術予測レポート 4巻 バイオテクノロジー編; 遺伝子相同組換えによる遺伝子操作の可能性(分担)

    森田 隆

    日本ビジネスレポート株式会社   4   17 - 26   2000

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    Publishing type:Article, review, commentary, editorial, etc. (other)  

  • ノックアウトマウスリスト 精子形成:減数分裂(分担)

    森田 隆 他

    (財)金原一郎記念医学医療振興財団/医学書   51 ( 5 )   479 - 480   2000

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • ゲノム保全システムとしてのDNA相同組換え機構  標的遺伝子組換えによる解析を中心として(分担)

    森田隆、吉村康秀、續輝久

    放射線生物研究   36 ( 3 )   250 - 267   2000

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 哺乳類の生殖生化学-マウスからヒトまで- 配偶子の形成:減数分裂(分担)

    森田 隆 他

    アイピーシー   1 - 19   1999

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    Publishing type:Article, review, commentary, editorial, etc. (other)  

  • ヒト染色体の分子生物学と遺伝子医学;染色体の組換え(分担)

    森田 隆 、土生敏行 他

    蛋白質 核酸 酵素   41   102 - 108   1996

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    Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

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Presentations

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Grant-in-Aid for Scientific Research

  • 宇宙サンプルを用いた宇宙放射線長期被ばくによる染色体異常の研究

    Grant-in-Aid for Scientific Research(C)  2023.04

  • 宇宙サンプルを用いた宇宙放射線長期被ばくによる染色体異常の研究

    Grant-in-Aid for Scientific Research(C)  2022.04

  • 宇宙サンプルを用いた宇宙放射線長期被ばくによる染色体異常の研究

    Grant-in-Aid for Scientific Research(C)  2021.04

  • 染色体軸-ループ構造(染色体3D構造)に基づく減数分裂期の染色体機能の制御

    Grant-in-Aid for Scientific Research on Innovative Areas  2019.04

  • 慢性腎不全の栄養障害・慢性炎症における細胞老化とDNA修復機構の役割の解明

    Grant-in-Aid for Scientific Research(C)  2017.04

  • 国際宇宙ステーション内に長期保存したマウス胚性幹細胞を用いた宇宙放射線の影響研究

    Grant-in-Aid for Scientific Research(C)  2015.04

  • 精子形成不全における温度依存的に影響を及ぼす分子の解明

    Grant-in-Aid for Scientific Research(C)  2013.04

  • 胚性幹細胞を用いた宇宙放射線の影響解析

    Grant-in-Aid for Scientific Research(C)  2012.04

  • 卵子の染色体異常と不妊に関する研究

    Grant-in-Aid for Young Scientists(B)  2009.04

  • 染色体異常による不妊に関する研究

    Grant-in-Aid for Young Scientists(B)  2007.04

  • 硫酸転移酵素遺伝子(Sultlc2)欠損マウスの作製による腎嚢胞形成の解析

    Grant-in-Aid for Scientific Research(C)  2004.04

  • 哺乳動物における相同組み換えタンパク(RAD51)の分子機能の解析

    Grant-in-Aid for Young Scientists(B)  2003.04

  • 組換え遺伝子(Rad51)を用いた難治がんの放射線治療

    Grant-in-Aid for Scientific Research on Priority Areas  2001.04

  • 組換え遺伝子(Rad51)を用いた耐性がんの治療

    Grant-in-Aid for Scientific Research on Priority Areas  2000.04

  • 哺乳動物における相同組換え遺伝子と細胞周期チェックポイントに関する研究

    Grant-in-Aid for Encouragement of Scientists  2000.04

  • DNA修復におけるRad51とP53遺伝子の役割

    Grant-in-Aid for Scientific Research on Priority Areas  1999.04

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Joint research

  • 遺伝子改変マウスを用いた宇宙放射線の影響の解析

    宇宙環境利用専門委員会(JAXA)  2021.09

  • 遺伝子改変マウスを用いた宇宙放射線の影響の解析

    宇宙環境利用専門委員会(JAXA)  2020.09

Other

  • Job Career

    2018.04 - Now

  • Job Career

    2018.04 - Now

  • Job Career

    2017.04 - 2018.03

  • Job Career

    2009.01 - 2017.03

  • Job Career

    2006.01 - 2008.12

  • Job Career

    2001.04 - 2005.12

  • Job Career

    1998.10 - 2001.03

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