The University of Tokyo   Molecular Cell Biology, Graduate School of Medicine

2012.03

IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-like actions of ketamine. Reviewed

Deyama S, Kondo M, Shimada S, Kaneda K.

Translational psychiatry   12 ( 1 )   178   2022.05

Development of a new method for assessing otolith function in mice using three-dimensional binocular analysis of the otolith-ocular reflex Reviewed

Harada S, Imai T, Takimoto Y, Ohta Y, Sato T, Kamakura T, Takeda N, Kitahara T, Kondo M, Ueno Y, Shimada S, Inohara H.

Scientific Reports   11 ( 1 )   17191   2021.12（ eISSN:2045-2322 ）

Zbtb16 regulates social cognitive behaviors and neocortical development. Reviewed

Usui N, Berto S, Konishi A, Kondo M, Konopka G, Matsuzaki H, Shimada S.

Translational Psychiatry   11 ( 1 )   2021.06（ eISSN:2158-3188 ）

Si-Based Hydrogen-Producing Nanoagent Protects Fetuses From Miscarriage Caused by Mother-to-Child Transmission Reviewed

Usui N, Togawa S, Sumi T, Kobayashi Y, Koyama Y, Nakamura Y, Kondo M, Shinoda K, Kobayashi H, Shimada S.

Frontiers in Medical Technology   3   2021.05（ eISSN:2673-3129 ）

Cochlear protection against noise exposure requires serotonin type 3A receptor via the medial olivocochlear system Reviewed

Ohata K, Kondo M, Ozono Y, Hanada Y, Sato T, Inohara H, Shimada S.

The FASEB Journal   35 ( 5 )   e21486   2021.05（ ISSN:0892-6638 ） （ eISSN:1530-6860 ）

Pain-like behavior in mice can be induced by the environmental context in which the pain stimulus was previously given Reviewed

Nakamura Y, Okano Y, Sato M, Kobayashi M, Yamaguchi T, Sumi T, Koyama Y, Kondo M, Usui N, Shimada S.

NeuroReport   32 ( 5 )   386 - 393   2021.02（ ISSN:0959-4965 ）

Contribution of Serotonin 3A Receptor to Motor Function and Its Expression in the Gastrointestinal Tract Reviewed

Aikiyo S, Kishi K, Kaji N, Mikawa S, Kondo M, Shimada S, Hori M.

Digestion   102 ( 4 )   1 - 11   2021（ ISSN:0012-2823 ） （ eISSN:1421-9867 ）

Bladder urothelium converts bacterial lipopolysaccharide information into neural signaling via an ATP-mediated pathway to enhance the micturition reflex for rapid defense Reviewed

Ueda N, Kondo M, Takezawa K, Kiuchi H, Sekii Y, Inagaki Y, Soda T, Fukuhara S, Fujita K, Uemura M, Imamura R, Miyagawa Y, Nonomura N, Shimada S.

Scientific Reports   10 ( 1 )   21167   2020.12（ eISSN:2045-2322 ）

前庭刺激によるマウスの眼球運動解析

原田 祥太郎, 今井 貴夫, 近藤 誠, 島田 晶一, 猪原 秀典

耳鼻咽喉科ニューロサイエンス   34   34 - 35   2020.06

Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent Reviewed

Kobayashi Y, Imamura R, Koyama Y, Kondo M, Kobayashi H, Nonomura N, Shimada S.

Scientific Reports   10 ( 1 )   2020.04（ eISSN:2045-2322 ）

Rat model of Ménière’s attack: intratympanic injection of potassium chloride produces direction-changing spontaneous nystagmus and hearing fluctuations. Reviewed

Kamakura T, Kitahara T, Kondo M, Horii A, Hanada Y, Takimoto Y, Ishida Y, Nakamura Y, Imai T, Inohara H, Shimada S.

Audiology & Neurotology   24 ( 5 )   217 - 223   2019.11（ ISSN:1420-3030 ） （ eISSN:1421-9700 ）

Yokukansan-induced reduction of ethanol preference is associated with antagonism of 5-HT3 receptors. Reviewed

Nakamura Y, Kondo M, Koyama Y, Shimada S.

Phytomedicine   59   152897   2019.06

Serotonin 3 receptor signaling regulates 5-fluorouracil-mediated apoptosis indirectly via TNF-α production by enhancing serotonin release from enterochromaffin cells. Reviewed

Mikawa S, Kondo M, Kaji N, Mihara T, Yoshitake R, Nakagawa T, Takamoto M, Nishimura R, Shimada S, Ozaki H, Hori M.

33   1669 - 1680   2019.02

SR 57227A is a partial agonist/partial antagonist of 5-HT3 receptor and inhibits subsequent 5-HT- or SR 57227A-induced 5-HT3 receptor current. Reviewed

Nakamura Y, Kondo M, Koyama Y, Shimada S.

Biochemical and Biophysical Research Communications   508 ( 2 )   590 - 596   2019.01

Intravesical ATP instillation induces urinary frequency because of activation of bladder afferent nerves without inflammatory changes in mice: a promising model for overactive bladder. Reviewed

Ueda N, Kondo M, Takezawa K, Kiuchi H, Sekii Y, Inagaki Y, Soda T, Fukuhara S, Fujita K, Uemura M, Imamura R, Miyagawa Y, Nonomura N, Shimada S.

Biochemical and Biophysical Research Communications   506 ( 3 )   498 - 503   2018.11

P2X2 receptor deficiency in mouse vestibular end organs attenuates vestibular function. Reviewed

Takimoto Y, Ishida Y, Kondo M, Imai T, Hanada Y, Ozono Y, Kamakura T, Inohara H, Shimada S.

Neuroscience   386   41 - 50   2018.08

Fibroblast growth factor 12 is expressed in spinal and vestibular ganglia and is necessary for auditory and equilibrium function.

Hanada Y, Nakamura Y, Ozono Y, Ishida Y, Takimoto Y, Taniguchi M, Ohata K, Koyama Y, Imai T, Morihana T, Kondo M, Sato T, Inohara H, Shimada S.

Scientific Reports   8 ( 1 )   11491   2018.07

A novel 5HT3 receptor-IGF1 mechanism distinct from SSRI-induced antidepressant effects. Reviewed

Kondo M, Koyama Y, Nakamura Y, Shimada S.

Molecular Psychiatry   23 ( 4 )   833 - 842   2018.04

BLADDER UROTHELIUM TRIGGERS AN IMMEDIATE DEFENSIVE RESPONSE AGAINST BACTERIAL LIPOPOLYSACCHARIDE VIA ATP SIGNALING Reviewed

Ueda Norichika, Kondo Makoto, Kiuchi Hiroshi, Inagaki Yusuke, Takezawa Kentaro, Fukuhara Shinichiro, Shimada Shoichi, Nonomura Norio

JOURNAL OF UROLOGY   199 ( 4 )   E398   2018.04

Yokukansan contains compounds that antagonize the 5-HT3 receptor. Reviewed

Nakamura Y, Ishida Y, Kondo M, Shimada S.

Phytomedicine   43   120 - 125   2018.04

Direct modification of the 5-HT3 receptor current by some anticancer drugs. Reviewed

Nakamura Y, Ishida Y, Kondo M, Shimada S.

European Journal of Pharmacology   821   21 - 28   2018.02

運動による抗うつ効果のメカニズムに基づいたうつ病の新規治療薬開発を目指して

近藤誠

月刊BIO INDUSTRY   34   36 - 44   2017.11

The significance of complete distributional analysis of the serotonin receptor. Reviewed

Koyama Y, Kondo M, Shimada S.

Neurotransmitter   4   1564   2017.06

THE ROLE OF UROTHELIAL ATP SIGNALING IN MICTURITION REFLEX Reviewed

Takezawa Kentaro, Kondo Makoto, Kiuchi Hiroshi, Ueda Norichika, Soda Tetsuji, Fukuhara Shinichiro, Takao Tetsuya, Miyagawa Yasushi, Tsujimura Akira, Matsumoto-Miyai Kazumasa, Ishida Yusuke, Negoro Hiromitsu, Shimada Shoichi, Nonomura Norio

JOURNAL OF UROLOGY   197 ( 4 )   E1351 - E1352   2017.04

Urothelial ATP signaling: what is its role in bladder sensation? Reviewed

Takezawa K, Kondo M, Nonomura N, Shimada S.

Neurourology and Urodynamics   36 ( 4 )   966 - 972   2017.04

Building a 5-HT3A Receptor Expression Map in the Mouse Brain. Reviewed

Koyama Y, Kondo M, Shimada S.

Scientific Reports   7   42884   2017.03

Molecular mechanisms of experience-dependent structural and functional plasticity in the brain. Invited Reviewed

Kondo M.

Anatomical Science International   92 ( 1 )   1 - 17   2017.01

Cisplatin-induced toxicity decreases the mouse vestibulo-ocular reflex. Reviewed

Takimoto Y, Imai T, Kondo M, Hanada Y, Uno A, Ishida Y, Kamakura T, Kitahara T, Inohara H, Shimada S.

Toxicology Letters   262   49 - 54   2016.11

脳の科学Up date 「運動が情動や記憶に影響を与える分子メカニズム」

近藤誠

脳21   19 ( 4 )   158 - 162   2016.10

Functional Expression of an Osmosensitive Cation Channel, Transient Receptor Potential Vanilloid 4, in Rat Vestibular Ganglia. Reviewed

Kamakura T, Kondo M, Koyama Y, Hanada Y, Ishida Y, Nakamura Y, Yamada T, Takimoto Y, Kitahara T, Ozono Y, Horii A, Imai T, Inohara H, Shimada S.

Audiology and Neuro-otology   21 ( 4 )   268 - 274   2016.10

刺激の豊かな環境や運動が脳に有益な効果をもたらす機序に関する研究から「こころの健康」を目指して

近藤誠

生存科学   26   77 - 80   2016.03

Authentic role of ATP signaling in micturition reflex. Reviewed

Takezawa K, Kondo M, Kiuchi H, Ueda N, Soda T, Fukuhara S, Takao T, Miyagawa Y, Tsujimura A, Matsumoto-Miyai K, Ishida Y, Negoro H, Ogawa O, Nonomura N, Shimada S.

Scientific Reports   6   19585   2016.01

環境や経験依存的な脳可塑性の分子メカニズムに関する研究

近藤誠

神経化学   54   60 - 62   2015.12

The 5-HT3 receptor is essential for exercise-induced hippocampal neurogenesis and antidepressant effects. Reviewed

Kondo M, Nakamura Y, Ishida Y, Shimada S.

Molecular Psychiatry   20 ( 11 )   1428 - 1437   2015.11

A NEW MECHANISM OF INFECTION-INDUCED BLADDER HYPERACTIVITY: LIPOPOLYSACCHARIDE CAUSES RAPID ATP RELEASE FROM UROTHELIUM AND STIMULATES THE MECHANOSENSORY AFFERENT PATHWAY. Reviewed

Takezawa Kentaro, Kondo Makoto, Kiuchi Hiroshi, Soda Tetsuji, Fukuhara Shinichiro, Takao Tetsuya, Miyagawa Yasushi, Tsujimura Akira, Matsumoto-Miyai Kazumasa, Shimada Shoichi, Nonomura Norio.

JOURNAL OF UROLOGY   193 ( 4 )   E80   2015.04

Exercise-induced neuronal effects and the 5-HT3 receptor. Reviewed

Kondo M, Shimada S.

Neurotransmitter   2   e764   2015.04

Serotonin and exercise-induced brain plasticity. Reviewed

Kondo M, Shimada S.

Neurotransmitter   2   e793   2015.04

Therapeutic action of 5-HT3 receptor antagonists targeting peritoneal macrophages in post-operative ileus. Reviewed

Maehara T, Matsumoto K, Horiguchi K, Kondo M, Iino S, Horie S, Murata T, Tsubone H, Shimada S, Ozaki H, Hori M.

British Journal of Pharmacology   172 ( 4 )   1136 - 1147   2015.02

Combination of bladder ultrasonography and novel cystometry method in mice reveals rapid decrease in bladder capacity and compliance in LPS-induced cystitis. Reviewed

Takezawa K, Kondo M, Kiuchi H, Soda T, Takao T, Miyagawa Y, Tsujimura A, Nonomura N, Shimada S.

American Journal of Physiology - Renal Physiology   307 ( 2 )   F234 - F241   2014.07

5-HT3 receptor expression in the mouse vestibular ganglion. Reviewed

Takimoto Y, Ishida Y, Nakamura Y, Kamakura T, Yamada T, Kondo M, Kitahara T, Uno A, Imai T, Horii A, Okazaki S, Nishiike S, Inohara H, Shimada S.

Brain Research   1557   74 - 82   2014.04

5-hydroxytryptamine type-3A receptor in the process of fear extinction. Reviewed

Kondo M, Shimada S.

Receptors & Clinical Investigation   1   33 - 37   2014.02

The 5-HT3A receptor is essential for fear extinction. Reviewed

Kondo M, Nakamura Y, Ishida Y, Yamada T, Shimada S.

Learning & Memory   21 ( 1 )   1 - 4   2014.01

Subunit-dependent inhibition and potentiation of 5-HT3 receptor by the anticancer drug, topotecan. Reviewed

Nakamura Y, Ishida Y, Yamada T, Kondo M, Shimada S.

Journal of Neurochemistry   125 ( 1 )   7 - 15   2013.04

刺激の豊かな生育環境での記憶や学習の向上にはモータータンパク質KIF1Aが必須である

近藤誠, 廣川信隆

ライフサイエンス新着論文レビュー   2012.03

Motor protein KIF1A is essential for hippocampal synaptogeness and learning enhancement in an enriched environment Reviewed

Kondo M, Takei Y, Hirokawa N.

Neuron   73 ( 4 )   743 - 757   2012.02

Anatomy and Neuroscience（Seminar 1）

2024     Graduate school

Basic Course of Molecular Medicine

2024     Graduate school

Molecular Medicine

2024     Graduate school

肉眼解剖学（マクロ）実習

2024   Weekly class   Undergraduate

感覚器・皮膚

2024   Weekly class   Undergraduate

神経解剖

2024   Weekly class   Undergraduate

循環器系

2024   Weekly class   Undergraduate

運動器系

2024   Weekly class   Undergraduate