Updated on 2023/03/31

写真a

 
OGINO Hiroyasu
 
Organization
Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology Professor
School of Engineering Department of Chemical Engineering
Title
Professor
Affiliation
Institute of Engineering
Contact information
メールアドレス
Affiliation campus
Nakamozu Campus

Position

  • Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology 

    Professor  2022.04 - Now

  • School of Engineering Department of Chemical Engineering 

    Professor  2022.04 - Now

Degree

  • 博士(工学) ( Others ) (   Osaka Prefecture University )

  • 工学修士 ( Others )

Research Areas

  • Life Science / Applied biochemistry  / 応用生物化学

  • Life Science / Applied microbiology  / 応用微生物学

  • Nanotechnology/Materials / Bio chemistry  / 生体関連化学

  • Nanotechnology/Materials / Chemistry and chemical methodology of biomolecules  / 生物分子科学

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Catalyst and resource chemical process  / 触媒・資源化学プロセス

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Chemical reaction and process system engineering  / 反応工学・プロセスシステム

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering  / 生物機能・バイオプロセス

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Research subject summary

  • 生体触媒(酵素・微生物)の産業的利用

  • 有機溶媒耐性微生物

  • 有機溶媒耐性酵素

Research Career

  • 生体触媒(酵素・微生物)の産業的利用

    1991 - Now 

  • 有機溶媒耐性酵素の探索・性質・利用・耐性機構の解明・タンパク質工学的作製

    酵素、有機溶媒、耐性、リパーゼ、プロテアーゼ 

    1991 - Now 

  • 微生物による遺伝子の発現・酵素のリフォールディング

    酵素、分泌、リフォールディング 

    1991 - Now 

Professional Memberships

  • 日本化学会

    2008.08 - Now

  • 極限環境生物学会

    2005.06 - Now

  • 酵素工学研究会

    2005.02 - Now

  • 日本生物工学会

    1991.06 - Now

  • 日本農芸化学会

    1991.04 - Now

  • 化学工学会

    1991.04 - Now

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Awards

  • 平成19年度 酵素工学奨励賞

    2007.10   酵素工学研究会  

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    Country:Japan

  • YABEC 2007 Poster Award

    2007.10   The 13th Symposium of Young Asian Biochemical Engineers' Community (YABEC 2007)  

Papers

  • Construction of a machine-learning model to predict the optimal gene expression level for efficient production of d-lactic acid in yeast Reviewed

    Yoshiki Yamamoto, Ryosuke Yamada, Takuya Matsumoto, and Hiroyasu Ogino

    World Journal of Microbiology and Biotechnology   39 ( 3 )   69   2023.03( ISSN:09593993

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    Authorship:Last author   International / domestic magazine:International journal  

    DOI: 10.1007/s11274-022-03515-x

    PubMed

  • Promoting cell growth and characterizing partial symbiotic relationships in the co-cultivation of green alga Chlamydomonas reinhardtii and Escherichia coli Reviewed International coauthorship

    Ryosuke Yamada, Moe Yokota, Takuya Matsumoto, Ben Hankamer, Hiroyasu Ogino

    Biotechnology Journal   18 ( 2 )   2023.02

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    Authorship:Last author   International / domestic magazine:International journal  

  • Mevalonate production by electro-fermentation in Escherichia coli via Mtr-based electron transfer system Reviewed

    Takuya Matsumoto, Kazuki Higuma, Ryosuke Yamada, Hiroyasu Ogino

    Biochemical Engineering Journal   191   2023.02( ISSN:1369703X

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    Authorship:Last author   International / domestic magazine:International journal  

    DOI: 10.1016/j.bej.2022.108772

  • Effect of attaching hydrophilic oligopeptides to the C-terminus of organic solvent-tolerant metal-free bromoperoxidase BPO-A1 from Streptomyces aureofaciens on organic solvent-stability Reviewed

    Hideyasu China and Hiroyasu Ogino

    Biochemical and Biophysical Research Communications   640   142 - 149   2023.01( ISSN:0006291X

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    Authorship:Last author, Corresponding author   International / domestic magazine:International journal  

    DOI: 10.1016/j.bbrc.2022.12.012

    PubMed

  • Identification of genes responsible for absorbing palladium ion in Escherichia coli. Reviewed

    Matsumoto T, Tanaka Y, Kamino M, Yamada R, Konishi Y, Ogino H

    Bioscience, biotechnology, and biochemistry   2023( ISSN:0916-8451

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    Authorship:Last author, Corresponding author   International / domestic magazine:International journal  

    DOI: 10.1093/bbb/zbad021

    PubMed

  • Mitochondrial expression of metabolic enzymes for improving carotenoid production in Saccharomyces cerevisiae Reviewed

    Takuya Matsumoto, Tomoki Osawa, Hikaru Taniguchi, Akira Saito, Ryosuke Yamada, and Hiroyasu Ogino

    Biochemical Engineering Journal   189   2022.12( ISSN:1369703X

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    Authorship:Last author, Corresponding author   International / domestic magazine:International journal  

    DOI: 10.1016/j.bej.2022.108720

  • Protein engineering to improve the stability of Thermomyces lanuginosus lipase in methanol Reviewed

    Taiki Okamura, Yohei Nogami, Takuya Matsumoto, Ryosuke Yamada, and Hiroyasu Ogino

    Biochemical Engineering Journal   187   2022.11( ISSN:1369703X

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    Authorship:Last author   International / domestic magazine:International journal  

    DOI: 10.1016/j.bej.2022.108659

  • Improving carotenoid production in recombinant yeast, Saccharomyces cerevisiae, using ultrasound-irradiated two-phase extractive fermentation Reviewed

    Ryosuke Yamada, Yorichika Ando, Ryosuke Mitsui, Asuka Mizobata, Shizue Yoshihara, Hayato Tokumoto, Takuya Matsumoto, Hiroyasu Ogino

    Engineering in Life Sciences   22   2022.01

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • Bioengineering for the industrial production of 2,3-butanediol by the yeast, Saccharomyces cerevisiae Reviewed

    Ryosuke Mitsui, Ryosuke Yamada, Takuya Matsumoto, and Hiroyasu Ogino

    World Journal of Microbiology and Biotechnology   38   2022.01

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    Kind of work:Joint Work   International / domestic magazine:International journal  

  • The synthesis of L-glycyl-L-tyrosine derivatives using organic-solvent stable PST-01 protease from Pseudomonas aeruginosa PST-01 Reviewed

    T. Matsumoto, R. Kitayama, R. Yamada, H. Ogino

    Process Biochemistry   102   2021.03

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • Improvement of 2,3-butanediol tolerance in Saccharomyces cerevisiae by using a novel mutagenesis strategy Reviewed

    A. Mizobata, R. Mitsui, R. Yamada, T. Matsumoto, S. Yoshihara, H. Tokumoto, H. Ogino

    Journal of Bioscience and Bioengineering   131   2021.03

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    Kind of work:Joint Work   International / domestic magazine:International journal  

  • Improvement of lactic acid tolerance by cocktail δ-integration strategy and identification of the transcription factor PDR3 responsible for lactic acid tolerance in yeast Saccharomyces cerevisiae Reviewed

    R. Yamada, Y. Kumata, R. Mitsui, T. Matsumoto, H. Ogino

    World Journal of Microbiology and Biotechnology   37   2021.01

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • Identification of genes responsible for reducing palladium ion in Escherichia coli Reviewed

    T. Matsumoto, M. Kamino, R. Yamada, Y. Konishi, H. Ogino

    Journal of Biotechnology   324   2020.12

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • Construction of lactic acid-tolerant Saccharomyces cerevisiae by using CRISPR-Cas-mediated genome evolution for efficient D-lactic acid production Reviewed

    R. Mitsui, R. Yamada, T. Matsumoto, S. Yoshihara, H. Tokumoto, H. Ogino

    Applied Microbiology and Biotechnology   104   2020.11

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • Construction of yeast producing patchoulol by global metabolic engineering strategy Reviewed

    R. Mitsui, R. Nishikawa, R. Yamada, T. Matsumoto, H. Ogino

    Biotechnology and Bioengineering   117   2020.01

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • N-linked glycosylation of thermostable lipase from Bacillus thermocatenulatus to improve organic solvent stability Reviewed

    S. Kajiwara, R. Yamada, T. Matsumoto, H. Ogino

    Enzyme Microb. Technol.   132   2020.01

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • Chemical treatments for modification and immobilization to improve the solvent-stability of lipase Reviewed

    T. Matsumoto, R. Yamada, H. Ogino

    World Journal of Microbiology and Biotechnology   35   2019.11

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • A useful propionate cofactor enhancing activity for organic solvent-tolerant recombinant metal-free bromoperoxidase (perhydrolase) from Streptomyces aureofaciens Reviewed

    H. China and H. Ogino

    Biochemical and Biophysical Research Communications   516 ( 2 )   2019.08

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    Kind of work:Joint Work   International / domestic magazine:International journal  

  • Cellulases and Xylanase Immobilized on Chitosan Magnetic Particles in Application for Coconut Husk Hydrolysis Reviewed International coauthorship

    Afan Hamzah, Sidratu Ainiyah, Dwi Ramadhani, Gek Ela Kumala Parwita, Yeni Rahmawati , Soeprijanto , Hiroyasu Ogino, Arief Widjaja

    International Journal of Technology   10 ( 3 )   613 - 623   2019.05

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    Kind of work:Joint Work  

  • Modification of lipase from Candida cylindracea with dextran using the borane-pyridine complex to improve organic solvent stability Reviewed

    S. Kajiwara, K. Komatsu, R. Yamada, T. Matsumoto, M. Yasuda, H. Ogino

    Journal of Biotechnology   296 ( 20 )   1 - 6   2019.04

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    Authorship:Last author   Kind of work:Joint Work   International / domestic magazine:International journal  

  • Toward the construction of a technology platform for chemicals production from methanol: D-lactic acid production from methanol by an engineered yeast Pichia pastoris Reviewed

    R. Yamada, K. Ogura, Y. Kimoto, H. Ogino

    World J. Microb. Biotechnol. 雑誌   35 ( 2 )   2019.02

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    Kind of work:Joint Work  

  • Secretory overexpression of the endoglucanase by Saccharomyces cerevisiae via CRISPR-delta-integration and multiple promoter shuffling Reviewed

    Y. Sasaki, R. Mitsui, R. Yamada, H. Ogino

    Enzyme Microb. Technol. 雑誌   121   17 - 22   2019.02

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    Kind of work:Joint Work  

  • Improvement of the organic solvent stability of a commercial lipase by chemical modification with dextran Reviewed

    S. Kajiwara, K. Komatsu, R. Yamada, T. Matsumoto, M. Yasuda, H. Ogino

    Biochem. Eng. J. 雑誌   142 ( 15 )   1 - 6   2019.02

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    Kind of work:Joint Work  

  • Improved stress tolerance of Saccharomyces cerevisiae by CRISPR-Cas-mediated genome evolution Reviewed

    R. Mitsuia, R. Yamada, H. Ogino

    Applied Biochemistry and Biotechnology 雑誌   2019

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    Kind of work:Joint Work  

  • CRISPR system in the yeast Saccharomyces cerevisiae and its application in the bioproduction of useful chemicals Reviewed

    R. Mitsui, R. Yamada, H. Ogino

    World J. Microb. Biotechnol. 雑誌   35   2019

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    Kind of work:Joint Work  

  • Modulation of gene expression by cocktail delta-integration to improve carotenoid production in Saccharomyces cerevisiae Reviewed

    R. Yamada, A. Yamauchi, Y. Ando, Y. Kumata, H. Ogino

    Bioresour. Technol. 雑誌   268   616 - 621   2018.11

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    Kind of work:Joint Work  

  • Enhancement of the catalytic activity of D-lactate dehydrogenase from Sporolactobacillus laevolacticus by site-directed mutagenesis Reviewed

    K. Nakano, S. Sawada, R. Yamada, T. Mimitsuka, H. Ogino

    Biochem. Eng. J. 雑誌   133   214 - 218   2018.05

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    Kind of work:Joint Work  

  • Rapid and stable production of 2,3-butanediol by an engineered Saccharomyces cerevisiae strain in a continuous airlift bioreactor Reviewed

    R. Yamada, R. Nishikawa, K. Wakita, H. Ogino

    J. Ind. Microbiol. Biotechnol. 雑誌   45 ( 5 )   2018.05

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    Kind of work:Joint Work  

  • Secretory overexpression of Bacillus thermocatenulatus lipase in Saccharomyces cerevisiae using combinatorial library strategy Reviewed

    S. Kajiwara, R. Yamada, H. Ogino

    Biotechnol. J. 雑誌   13 ( 8 )   2018

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    Kind of work:Joint Work  

  • Evaluation of lipid production from xylose and glucose/xylose mixed sugar in various oleaginous yeasts and improvement of lipid production by UV mutagenesis Reviewed

    R. Yamada, A. Yamauchi, T. Kashihara, H. Ogino

    Biochem. Eng. J. 雑誌   128   76 - 82   2017.12

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    Kind of work:Joint Work  

  • Efficient production of 2,3-butanediol by recombinant Saccharomyces cerevisiae through modulation of gene expression by cocktail delta-integration Reviewed

    R. Yamada, K. Wakita, R. Mitsui, R. Nishikawa, H. Ogino

    Bioresour. Technol. 雑誌   245   1558 - 1566   2017.12

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    Kind of work:Joint Work  

  • Enhanced D-lactic acid production by recombinant Saccharomyces cerevisiae following optimization of the global metabolic pathway Reviewed

    R. Yamada, K. Wakita, R. Mitsui, H. Ogino

    Biotechnol. Bioeng. 雑誌   114 ( 9 )   2017.09

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    Kind of work:Joint Work  

  • Improvement of Lipid Production by the Oleaginous Yeast Rhodosporidium toruloides through UV Mutagenesis Reviewed

    R. Yamada, T. Kashihara, H. Ogino

    World J. Microbiol. Biotechnol. 雑誌   33 ( 5 )   2017.05

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    Kind of work:Joint Work  

  • Development of sucrose-complexed lipase to improve its transesterification activity and stability in organic solvents Reviewed

    S. Kajiwara, R. Yamada, H. Mori, M. Hara, H. Ogino

    Biochem. Eng. J. 雑誌   121   83 - 87   2017.05

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    Kind of work:Joint Work  

  • Global metabolic engineering of glycolytic pathway via multicopy integration in Saccharomyces cerevisiae Reviewed

    R. Yamada, K. Wakita, H. Ogino

    ACS Synth. Biol. 雑誌   6 ( 4 )   659 - 666   2017.04

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    Kind of work:Joint Work  

  • Random mutagenesis and selection of organic solvent-stable haloperoxidase from Streptomyces aureofaciens Reviewed

    R. Yamada, T. Higo, C. Yoshikawa, H. China, M. Yasuda, and H. Ogino

    Biotechnol. Prog. 雑誌   2015.07

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    Kind of work:Joint Work  

  • Improvement of the stability and activity of the BPO-A1 haloperoxidase from Streptomyces aureofaciens by directed evolution Reviewed

    R. Yamada, T. Higo, C. Yoshikawa, H. China, and H. Ogino

    J. Biotechnol. 雑誌   2014.12

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    Kind of work:Joint Work  

  • Hyper-activation of foldase-dependent lipase with lipase-specific foldase Reviewed

    Hiroyasu Ogino, Sosuke Inoue, Masahiro Yasuda, Noriyuki Doukyu

    Journal of Biotechnology 雑誌   166 ( 1-2 )   20 - 24   2013.06

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    Kind of work:Joint Work  

  • Amino acid residues involved in organic solvent-stability of the LST-03 lipase Reviewed

    Takuya Kawata, Hiroyasu Ogino

    Biochemical and Biophysical Research Communications 雑誌   400 ( 3 )   2010.10

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    Kind of work:Joint Work  

  • Enhancement of the aspartame precursor synthetic activity of an organic solvent-stable protease Reviewed

    H. Ogino, S. Tsuchiyama, M. Yasuda, and N. Doukyu

    Protein Eng. Des. Sel. 雑誌   23 ( 3 )   147 - 152   2010.03

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    Kind of work:Joint Work  

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Books and Other Publications

  • 「バイオリアクターのスケールアップと物質生産事例集」第8章 バイオリアクターを利用した物質生産の事例:素材・エネルギー編 7節 バイオリアクターを用いた酵母による2,3-ブタンジオール生産

    山田亮祐,荻野博康( Role: Joint author)

    技術情報協会  2021.04 

  • 基礎から理解する化学4 化学工学

    関実, 松村幸彦, 塚田隆夫, 荻野博康, 車田研一, 菊池康紀, 常田聡, 福長博, 原野安土, 渡邉智秀( Role: Joint author)

    (株)医学評論社  2012.04 

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    Responsible for pages:49-68, 208-209  

  • 生物化学工学 第3版

    丹治保典, 今井正直, 養王田正文, 荻野博康( Role: Joint author)

    講談社  2011.09 

  • 酵素利用技術大系

    荻野博康( Role: Joint author)

    株式会社エヌ・ティー・エス  2010.04 

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    Responsible for pages:526-530  

  • Protein Adaptation in Extremophiles

    H. Ogino( Role: Joint author)

    Nova Science Publishers Inc  2008.02 

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    Responsible for pages:193-236  

Industrial Property Rights

  • 変異型プロテアーゼ及び該プロテアーゼを用いたペプチド合成方法

    荻野博康

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    property_type:Patent 

  • 高比活性リパーゼの調製方法

    荻野博康・西矢芳昭

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    property_type:Patent 

  • リパーゼ

    田中亨,堀田康司,石川治男,荻野博康

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    property_type:Patent 

Outline of collaborative research (seeds)

  • 生体触媒(酵素・微生物)の産業的利用

  • 有機溶媒耐性酵素

     More details

    有機溶媒耐性酵素の探索・性質・利用・耐性機構の解明・タンパク質工学的作製

  • 有機溶媒耐性微生物

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    有機溶媒耐性微生物の探索・性質・利用

Charge of on-campus class subject

  • Chemical Reaction Engineering II

    2021    

  • Introduction to Materials, Chemistry and Chemical Engineering

    2021    

  • Selected Topics in Chemical Reaction Engineering

    2021    

  • Advanced Chemical Reaction Engineering

    2021    

  • Chemical Reaction Engineering I

    2021    

  • Biochemical Engineering

    2021    

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Charge of off-campus class subject

  • 化学方法論(化学)

    2018.04
    -
    Now
    Institution:Kinki University

  • 反応工学

    2010.10
    -
    2011.03
    Institution:Wakayama National College of Technology

  • 特別講義III

    2009.04
    -
    2009.09
    Institution:Kobe University

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    Level:Postgraduate 

  • 化学工学2

    2005.04
    -
    2023.03
    Institution:Kinki University

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    Level:Undergraduate (specialized) 

  • 化学工学1

    2005.04
    -
    2008.03
    Institution:Kinki University

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    Level:Undergraduate (specialized) 

  • 生物工学

    2005.04
    -
    2005.09
    Institution:Osaka Prefectural College of Technology

  • 化学工学

    2004.04
    -
    2005.03
    Institution:Kinki University

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    Level:Undergraduate (specialized) 

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