Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Chemical reaction and process system engineering  / 反応工学・プロセスシステム

Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering  / 生物機能・バイオプロセス

化学工学会

1991.04 - Now

Co-culture systems of microalgae and heterotrophic microorganisms: applications in bioproduction and wastewater treatment and elucidation of mutualistic interactions Reviewed

M. Takahashi, R. Yamada, T. Matsumoto, H. Ogino

World Journal of Microbiology and Biotechnology   40   368   2024.10

Reshaping the substrate‐binding pocket of acyl‐ACP reductase to enhance the production of sustainable aviation fuel in Escherichia coli Reviewed

J. Han, T. Matsumoto, R. Yamada, H. Ogino

Biotechnology and Bioengineering   122 ( 1 )   211 - 222   2024.10

Co-utilization of microalgae and heterotrophic microorganisms improves wastewater treatment efficiency Reviewed

M. Takahashi, Y. Karitani, R. Yamada, T. Matsumoto, H. Ogino

Applied Microbiology and Biotechnology   108   468   2024.09

Induction of point and structural mutations in engineered yeast Saccharomyces cerevisiae improve carotenoid production Reviewed

R. Yamada, K. Ando, R. Sakaguchi, T. Matsumoto, H. Ogino

World Journal of Microbiology and Biotechnology   40   230   2024.06

Development of a metabolic engineering technology to simultaneously suppress the expression of multiple genes in yeast and application in carotenoid production Reviewed

R. Yamada, C. Yamamoto, R. Sakaguchi, T. Matsumoto, H. Ogino

World Journal of Microbiology and Biotechnology   40   227   2024.06

Improvement of cell growth in green algae Chlamydomonas reinhardtii through co-cultivation with yeast Saccharomyces cerevisiae Reviewed

Y. Karitani, R. Yamada*, T. Matsumoto, H. Ogino

Biotechnology Letters   46   431 - 441   2024.04

UV mutagenesis improves growth potential of green algae in a green algae-yeast co-culture system Reviewed

Y. Karitani, R. Yamada, T. Matsumoto, H. Ogino

Archives of Microbiology   206 ( 2 )   61   2024.01

Display of PETase on the cell surface of Escherichia coli using the anchor protein PgsA Reviewed

T. Yamashita, T. Matsumoto, R. Yamada, H. Ogino

Applied Biochemistry and Biotechnology   1 - 13   2024.01

Building a machine-learning model to predict optimal mevalonate pathway gene expression levels for efficient production of a carotenoid in yeast Reviewed

R. Yamada, Y. Yamamoto, T. Matsumoto, H. Ogino

Biotechnology Journal   19 ( 1 )   e2300285   2024.01

Transition of stability of putidaredoxin reductase by introducing proline Reviewed

T. Okamura, R. Aritomi, T. Matsumoto, R. Yamada, H. Hirakawa, H. Ogino

Biochemical Engineering Journal   201   109139   2024.01

Enhancing 3-hydroxypropionic acid production in Saccharomyces cerevisiae through enzyme localization within mitochondria Reviewed

T. Matsumoto, T. Otani, R. Yamada, H. Ogino

Biochemical and Biophysical Research Communications   680   1 - 6   2023.11

Engineering acyl-ACP reductase with fusion tags enhances alka(e)ne synthesis in Escherichia coli Reviewed

J. Han, K. Asano, T. Matsumoto, R. Yamada, H. Ogino

Enzyme and Microbial Technology   168   110262   2023.08

Identification of genes responsible for absorbing palladium ion in Escherichia coli Reviewed

T. Matsumoto, Y. Tanaka, M. Kamino, R. Yamada, Y. Konishi, H. Ogino

Bioscience, Biotechnology, and Biochemistry   87 ( 5 )   569 - 571   2023.05

Construction of a machine-learning model to predict the optimal gene expression level for efficient production of d-lactic acid in yeast Reviewed

Yoshiki Yamamoto, Ryosuke Yamada, Takuya Matsumoto, and Hiroyasu Ogino

World Journal of Microbiology and Biotechnology   39 ( 3 )   69   2023.03（ ISSN:09593993 ）

Mevalonate production by electro-fermentation in Escherichia coli via Mtr-based electron transfer system Reviewed

Takuya Matsumoto, Kazuki Higuma, Ryosuke Yamada, Hiroyasu Ogino

Biochemical Engineering Journal   191   2023.02（ ISSN:1369703X ）

Promoting cell growth and characterizing partial symbiotic relationships in the co-cultivation of green alga Chlamydomonas reinhardtii and Escherichia coli Reviewed International coauthorship

Ryosuke Yamada, Moe Yokota, Takuya Matsumoto, Ben Hankamer, Hiroyasu Ogino

Biotechnology Journal   18 ( 2 )   2023.02

Effect of attaching hydrophilic oligopeptides to the C-terminus of organic solvent-tolerant metal-free bromoperoxidase BPO-A1 from Streptomyces aureofaciens on organic solvent-stability Reviewed

Hideyasu China and Hiroyasu Ogino

Biochemical and Biophysical Research Communications   640   142 - 149   2023.01（ ISSN:0006291X ）

Mitochondrial expression of metabolic enzymes for improving carotenoid production in Saccharomyces cerevisiae Reviewed

Takuya Matsumoto, Tomoki Osawa, Hikaru Taniguchi, Akira Saito, Ryosuke Yamada, and Hiroyasu Ogino

Biochemical Engineering Journal   189   2022.12（ ISSN:1369703X ）

Protein engineering to improve the stability of Thermomyces lanuginosus lipase in methanol Reviewed

Taiki Okamura, Yohei Nogami, Takuya Matsumoto, Ryosuke Yamada, and Hiroyasu Ogino

Biochemical Engineering Journal   187   2022.11（ ISSN:1369703X ）

Improving carotenoid production in recombinant yeast, Saccharomyces cerevisiae, using ultrasound-irradiated two-phase extractive fermentation Reviewed

Ryosuke Yamada, Yorichika Ando, Ryosuke Mitsui, Asuka Mizobata, Shizue Yoshihara, Hayato Tokumoto, Takuya Matsumoto, Hiroyasu Ogino

Engineering in Life Sciences   22   2022.01

Bioengineering for the industrial production of 2,3-butanediol by the yeast, Saccharomyces cerevisiae Reviewed

Ryosuke Mitsui, Ryosuke Yamada, Takuya Matsumoto, and Hiroyasu Ogino

World Journal of Microbiology and Biotechnology   38   2022.01

The synthesis of L-glycyl-L-tyrosine derivatives using organic-solvent stable PST-01 protease from Pseudomonas aeruginosa PST-01 Reviewed

T. Matsumoto, R. Kitayama, R. Yamada, H. Ogino

Process Biochemistry   102   2021.03

Improvement of 2,3-butanediol tolerance in Saccharomyces cerevisiae by using a novel mutagenesis strategy Reviewed

A. Mizobata, R. Mitsui, R. Yamada, T. Matsumoto, S. Yoshihara, H. Tokumoto, H. Ogino

Journal of Bioscience and Bioengineering   131   2021.03

Improvement of lactic acid tolerance by cocktail δ-integration strategy and identification of the transcription factor PDR3 responsible for lactic acid tolerance in yeast Saccharomyces cerevisiae Reviewed

R. Yamada, Y. Kumata, R. Mitsui, T. Matsumoto, H. Ogino

World Journal of Microbiology and Biotechnology   37   2021.01

Identification of genes responsible for reducing palladium ion in Escherichia coli Reviewed

T. Matsumoto, M. Kamino, R. Yamada, Y. Konishi, H. Ogino

Journal of Biotechnology   324   2020.12

Construction of lactic acid-tolerant Saccharomyces cerevisiae by using CRISPR-Cas-mediated genome evolution for efficient D-lactic acid production Reviewed

R. Mitsui, R. Yamada, T. Matsumoto, S. Yoshihara, H. Tokumoto, H. Ogino

Applied Microbiology and Biotechnology   104   2020.11

N-linked glycosylation of thermostable lipase from Bacillus thermocatenulatus to improve organic solvent stability Reviewed

S. Kajiwara, R. Yamada, T. Matsumoto, H. Ogino

Enzyme Microb. Technol.   132   2020.01

Construction of yeast producing patchoulol by global metabolic engineering strategy Reviewed

R. Mitsui, R. Nishikawa, R. Yamada, T. Matsumoto, H. Ogino

Biotechnology and Bioengineering   117   2020.01

Chemical treatments for modification and immobilization to improve the solvent-stability of lipase Reviewed

T. Matsumoto, R. Yamada, H. Ogino

World Journal of Microbiology and Biotechnology   35   2019.11

A useful propionate cofactor enhancing activity for organic solvent-tolerant recombinant metal-free bromoperoxidase (perhydrolase) from Streptomyces aureofaciens Reviewed

H. China and H. Ogino

Biochemical and Biophysical Research Communications   516 ( 2 )   2019.08

Cellulases and Xylanase Immobilized on Chitosan Magnetic Particles in Application for Coconut Husk Hydrolysis Reviewed International coauthorship

Afan Hamzah, Sidratu Ainiyah, Dwi Ramadhani, Gek Ela Kumala Parwita, Yeni Rahmawati , Soeprijanto , Hiroyasu Ogino, Arief Widjaja

International Journal of Technology   10 ( 3 )   613 - 623   2019.05

Modification of lipase from Candida cylindracea with dextran using the borane-pyridine complex to improve organic solvent stability Reviewed

S. Kajiwara, K. Komatsu, R. Yamada, T. Matsumoto, M. Yasuda, H. Ogino

Journal of Biotechnology   296 ( 20 )   1 - 6   2019.04

Toward the construction of a technology platform for chemicals production from methanol: D-lactic acid production from methanol by an engineered yeast Pichia pastoris Reviewed

R. Yamada, K. Ogura, Y. Kimoto, H. Ogino

World J. Microb. Biotechnol. 雑誌   35 ( 2 )   2019.02

Secretory overexpression of the endoglucanase by Saccharomyces cerevisiae via CRISPR-delta-integration and multiple promoter shuffling Reviewed

Y. Sasaki, R. Mitsui, R. Yamada, H. Ogino

Enzyme Microb. Technol. 雑誌   121   17 - 22   2019.02

Improvement of the organic solvent stability of a commercial lipase by chemical modification with dextran Reviewed

S. Kajiwara, K. Komatsu, R. Yamada, T. Matsumoto, M. Yasuda, H. Ogino

Biochem. Eng. J. 雑誌   142 ( 15 )   1 - 6   2019.02

Improved stress tolerance of Saccharomyces cerevisiae by CRISPR-Cas-mediated genome evolution Reviewed

R. Mitsuia, R. Yamada, H. Ogino

Applied Biochemistry and Biotechnology 雑誌   2019

CRISPR system in the yeast Saccharomyces cerevisiae and its application in the bioproduction of useful chemicals Reviewed

R. Mitsui, R. Yamada, H. Ogino

World J. Microb. Biotechnol. 雑誌   35   2019

Modulation of gene expression by cocktail delta-integration to improve carotenoid production in Saccharomyces cerevisiae Reviewed

R. Yamada, A. Yamauchi, Y. Ando, Y. Kumata, H. Ogino

Bioresour. Technol. 雑誌   268   616 - 621   2018.11

Enhancement of the catalytic activity of D-lactate dehydrogenase from Sporolactobacillus laevolacticus by site-directed mutagenesis Reviewed

K. Nakano, S. Sawada, R. Yamada, T. Mimitsuka, H. Ogino

Biochem. Eng. J. 雑誌   133   214 - 218   2018.05

Rapid and stable production of 2,3-butanediol by an engineered Saccharomyces cerevisiae strain in a continuous airlift bioreactor Reviewed

R. Yamada, R. Nishikawa, K. Wakita, H. Ogino

J. Ind. Microbiol. Biotechnol. 雑誌   45 ( 5 )   2018.05

Secretory overexpression of Bacillus thermocatenulatus lipase in Saccharomyces cerevisiae using combinatorial library strategy Reviewed

S. Kajiwara, R. Yamada, H. Ogino

Biotechnol. J. 雑誌   13 ( 8 )   2018

Evaluation of lipid production from xylose and glucose/xylose mixed sugar in various oleaginous yeasts and improvement of lipid production by UV mutagenesis Reviewed

R. Yamada, A. Yamauchi, T. Kashihara, H. Ogino

Biochem. Eng. J. 雑誌   128   76 - 82   2017.12

Efficient production of 2,3-butanediol by recombinant Saccharomyces cerevisiae through modulation of gene expression by cocktail delta-integration Reviewed

R. Yamada, K. Wakita, R. Mitsui, R. Nishikawa, H. Ogino

Bioresour. Technol. 雑誌   245   1558 - 1566   2017.12

Enhanced D-lactic acid production by recombinant Saccharomyces cerevisiae following optimization of the global metabolic pathway Reviewed

R. Yamada, K. Wakita, R. Mitsui, H. Ogino

Biotechnol. Bioeng. 雑誌   114 ( 9 )   2017.09

Improvement of Lipid Production by the Oleaginous Yeast Rhodosporidium toruloides through UV Mutagenesis Reviewed

R. Yamada, T. Kashihara, H. Ogino

World J. Microbiol. Biotechnol. 雑誌   33 ( 5 )   2017.05

Development of sucrose-complexed lipase to improve its transesterification activity and stability in organic solvents Reviewed

S. Kajiwara, R. Yamada, H. Mori, M. Hara, H. Ogino

Biochem. Eng. J. 雑誌   121   83 - 87   2017.05

Global metabolic engineering of glycolytic pathway via multicopy integration in Saccharomyces cerevisiae Reviewed

R. Yamada, K. Wakita, H. Ogino

ACS Synth. Biol. 雑誌   6 ( 4 )   659 - 666   2017.04

Random mutagenesis and selection of organic solvent-stable haloperoxidase from Streptomyces aureofaciens Reviewed

R. Yamada, T. Higo, C. Yoshikawa, H. China, M. Yasuda, and H. Ogino

Biotechnol. Prog. 雑誌   2015.07

Improvement of the stability and activity of the BPO-A1 haloperoxidase from Streptomyces aureofaciens by directed evolution Reviewed

R. Yamada, T. Higo, C. Yoshikawa, H. China, and H. Ogino

J. Biotechnol. 雑誌   2014.12

Hyper-activation of foldase-dependent lipase with lipase-specific foldase Reviewed

Hiroyasu Ogino, Sosuke Inoue, Masahiro Yasuda, Noriyuki Doukyu

Journal of Biotechnology 雑誌   166 ( 1-2 )   20 - 24   2013.06

Amino acid residues involved in organic solvent-stability of the LST-03 lipase Reviewed

Takuya Kawata, Hiroyasu Ogino

Biochemical and Biophysical Research Communications 雑誌   400 ( 3 )   2010.10

Enhancement of the aspartame precursor synthetic activity of an organic solvent-stable protease Reviewed

H. Ogino, S. Tsuchiyama, M. Yasuda, and N. Doukyu

Protein Eng. Des. Sel. 雑誌   23 ( 3 )   147 - 152   2010.03

PET分解酵素を表層提示した大腸菌触媒の開発

藏内佑斗，松本拓也，山田亮祐，荻野博康

化学工学会第90年会  2025.03  化学工学会

カロテノイド生産酵母への変異導入における集積培養条件の検討

室井誠，山田亮祐，松本拓也，荻野博康

化学工学会第90年会  2025.03  化学工学会

PET分解酵素を表層提示した大腸菌触媒の開発

藏内佑斗，松本拓也，山田亮祐，荻野博康

酵素工学研究会第92回講演会  2024.11  酵素工学研究会

高機能生体触媒の開発 Invited

荻野博康

第1回BRRPセミナー  2024.10  東洋大学バイオレジリエンス研究プロジェクト

Reshaping the substrate-binding pocket of acyl-ACP reductase to enhance the production of sustainable aviation fuel in Escherichia coli International conference

Jiahu Han，Takuya Matsumoto，Ryosuke Yamada，Hiroyasu Ogino

2024.10 

アシル-ACP還元酵素の基質結合ポケットの再構築による大腸菌での持続可能な航空燃料生産の強化

韓佳虎，松本拓也，山田亮祐，荻野博康

超越分子システム第3回若手会  2024.10 

酵母ミトコンドリアを利用した3-ヒドロキシプロピオン酸生産

中村あさ陽，松本拓也，山田亮祐，荻野博康

超越分子システム第3回若手会  2024.10 

PET分解酵素を表層提示した大腸菌触媒の開発

藏内佑斗，松本拓也，山田亮祐，荻野博康

超越分子システム第3回若手会  2024.10 

Optimization of D-LDH gene expression for D-lactic acid production from methanol by engineered Komagataella phaffii International conference

oshifumi Inoue，Ryosuke Yamada，Takuya Matsumoto， Hiroyasu Ogino

2024.10 

The surface design of Escherichia coli for efficient PET degradation International conference

Takuya Matsumoto，Yuto Kurauchi，Ryosuke Yamada，Hiroyasu Ogino

2024.10 

Reshaping the substrate-binding pocket of acyl-ACP reductase to enhance the production of sustainable aviation fuel in Escherichia coli

韓佳虎，松本拓也，山田亮祐，荻野博康

化学工学会第55回秋季大会  2024.09  化学工学会

点変異と構造変異の導入による酵母の2,3-ブタンジオール耐性向上

中村海斗，山田亮祐，松本拓也，荻野博康

化学工学会第55回秋季大会  2024.09  化学工学会

Komagataella phaffiiへのD-LDH遺伝子多コピー組込みによるメタノールからのD-乳酸生産性向上

井上義文，山田亮祐，松本拓也，荻野博康

化学工学会第55回秋季大会  2024.09  化学工学会

微細藻類と従属栄養微生物との共培養による排水処理効率の向上

高橋美郁，山田亮祐，松本拓也，荻野博康

生物工学若手研究者の集い夏のセミナー  2024.07 

酵母における複数遺伝子同時発現抑制技術の開発とβ-カロテン生産への応用

山田亮祐，山本千尋，松本拓也，荻野博康

生物工学若手研究者の集い夏のセミナー  2024.07 

メタノール資化性酵母によるD-乳酸生産を目指したD-LDH発現の検討

井上義文，山田亮祐，松本拓也，荻野博康

生物工学若手研究者の集い夏のセミナー  2024.07 

物質化学生命系特別演習

2024   Intensive lecture   Graduate school

生物化学工学

2024   Weekly class   Undergraduate

反応工学1

2024   Weekly class   Undergraduate

物質化学生命系特別演習第2

2024   Intensive lecture   Graduate school

化学工学特別学外実習

2024   Intensive lecture   Graduate school

物質化学生命系特別研究第2

2024   Intensive lecture   Graduate school

物質化学生命系特別研究

2024   Intensive lecture   Graduate school

反応工学特別講義

2024   Weekly class   Graduate school

化学工学序論

2023   Weekly class   Undergraduate

物質化学生命系特別演習

2023   Intensive lecture   Graduate school

化学工学特別学外実習

2023   Intensive lecture   Graduate school

反応工学特論

2023   Weekly class   Graduate school

物質化学生命系特別研究第1

2023   Intensive lecture   Graduate school

物質化学生命系特別演習第1

2023   Intensive lecture   Graduate school

反応工学II

2023   Weekly class   Undergraduate

生物化学工学

2023   Weekly class   Undergraduate

物質化学生命系特別研究

2023   Intensive lecture   Graduate school

物質化学生命系特別研究第2

2023   Intensive lecture   Graduate school

物質化学生命系特別演習第2

2023   Intensive lecture   Graduate school

反応工学1

2023   Weekly class   Undergraduate

反応工学特別講義

2023   Weekly class   Graduate school

化学工学序論

2022   Weekly class   Undergraduate

反応工学特論

2022   Weekly class   Graduate school

物質化学生命系特別演習第1

2022   Intensive lecture   Graduate school

反応工学II

2022   Weekly class   Undergraduate

工学研究の最先端

2022   Intensive lecture   Undergraduate

物質化学生命系特別演習

2022   Intensive lecture   Graduate school

物質化学生命系特別演習第2 （化学工学分野）

2022   Intensive lecture   Graduate school

化学工学特別学外実習 （化学工学分野）

2022   Intensive lecture   Graduate school

生物化学工学

2022   Weekly class   Undergraduate

反応工学I

2022   Weekly class   Undergraduate

反応工学特別講義

2022   Weekly class   Graduate school

物質化学生命系特別研究 （化学工学分野）

2022   Intensive lecture   Graduate school

Chemical Reaction Engineering II

2021    

Introduction to Materials, Chemistry and Chemical Engineering

2021    

Selected Topics in Chemical Reaction Engineering

2021    

Advanced Chemical Reaction Engineering

2021    

Chemical Reaction Engineering I

2021    

Biochemical Engineering

2021    

生物工学

化学工学