Crystal structure of exo-rhamnogalacturonan lyase from Penicillium chrysogenum as a member of polysaccharide lyase family 26. Reviewed

Kunishige Y, Iwai M, Nakazawa M, Ueda M, Tada T, Nishimura S, Sakamoto T.

FEBS Lett. 雑誌   592 ( 8 )   2018.04

Mechanism of chitosan recognition by CBM32 carbohydrate-binding modules from a Paenibacillus sp. IK-5 chitosanase/glucanase. Reviewed

Shinya S, Nishimura S, Kitaoku Y, Numata T, Kimoto H, Kusaoke H, Ohnuma T, Fukamizo T.

Biochem J. 雑誌   473 ( 8 )   2016.04

Characterization of the novel Trypanosoma brucei inosine 5'-monophosphate dehydrogenase. Reviewed

Bessho T, Morii S, Kusumoto T, Shinohara T, Noda M, Uchiyama S, Shuto S, Nishimura S, Djikeng A, Duszenko M, Martin SK, Inui T, Kubata KB.

Parasitology   140 ( 6 )   735 - 45   2013.05

Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase. Reviewed

Fukuhara A, Nakajima H, Miyamoto Y, Inoue K, Kume S, Lee YH, Noda M, Uchiyama S, Shimamoto S, Nishimura S, Ohkubo T, Goto Y, Takeuchi T, Inui T.

J Control Release 雑誌   159 ( 1 )   143 - 50   2012.04

NMR and CD analysis of an intermediate state in the thermal unfolding process of mouse lipocalin-type prostaglandin D synthase. Reviewed

Miyamoto Y, Noda Y, Iida T, Yamaguchi K, Nishimura S, Tanaka A, Segawa S, Inui T.

J Biochem 雑誌   151 ( 3 )   335 - 42   2012.03

A rapid and simple method of evaluating the dimeric tendency of fluorescent proteins in living cells using a truncated protein of importin α as fusion tag. Reviewed

Nakagawa C, Nishimura S, Senda-Murata K, Sugimoto K.

Biosci Biotechnol Biochem. 雑誌   76 ( 2 )   388 - 90   2012.02

Interaction of a goose-type lysozyme with chitin oligosaccharides as determined by NMR spectroscopy. Reviewed

Shinya S, Ohnuma T, Kawamura S, Torikata T, Nishimura S, Katoh E, Fukamizo T.

J Biochem. 雑誌   150 ( 5 )   569 - 77   2011.11

Backbone chemical shifts assignments, secondary structure, and ligand binding of a family GH-19 chitinase from moss, Bryum coronatum.

Shinya S, Nagata T, Ohnuma T, Taira T, Nishimura S, Fukamizo T.

Biomol NMR Assign 雑誌   2011.11

Improvement of a Venus-based bimolecular fluorescence complementation assay to visualize bFos-bJun interaction in living cells. Reviewed

Nakagawa C, Inahata K, Nishimura S, Sugimoto K.

Biosci Biotechnol Biochem. 雑誌   75 ( 7 )   1399 - 401   2011.07

Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site Reviewed

Tsuji H, Nishimura S, Inui T, Kado Y, Ishikawa K, Nakamura T, Uegaki K.

FEBS Journal 雑誌   277 ( 12 )   2683 - 95   2010.06

Structural analysis of lipocalin-type prostaglandin D synthase complexed with biliverdin by small-angle X-ray scattering and multi-dimensional NMR. Reviewed

Miyamoto Y, Nishimura S, Inoue K, Shimamoto S, Yoshida T, Fukuhara A, Yamada M, Urade Y, Yagi N, Ohkubo T, Inui T.

J. Struct. Biol. 雑誌   169 ( 2 )   209 - 18   2010.02

Kinetically trapped metastable intermediate of a disulfide-deficient mutant of the starch-binding domain of glucoamylase. Reviewed

Sugimoto H, Nakaura M, Nishimura S, Karita S, Miyake H, Tanaka A.

Protein Sci. 雑誌   18 ( 8 )   1715 - 23   2009.08

Thermal unfolding mechanism of lipocalin-type prostaglandin D synthase Reviewed

Tsukimi Iida, Shigenori Nishimura, Maki Mochizuki, Susumu Uchiyama, Tadayasu Ohkubo, Yoshihiro Urade, Akiyoshi Tanaka, Takashi Inui

FEBS Journal 雑誌   275 ( 2 )   233 - 241   2007.12

Conformational analysis of human calcitonin in solution. Reviewed

Kiyoshi Ogawa, Shigenori Nishimura, Masamitsu Doi, H Takashima, Y Nishi, Takuya Yoshida, Tadayasu Ohkubo, Yuji Kobayashi

J. Pept. Sci. 雑誌   12 ( 1 )   51 - 57   2006.01

Two Additional Carbohydrate-Binding Sites of β-Amylase from Bacillus cereus var. mycoides Are Involved in Hydrolysis and Raw Starch-Binding Reviewed

Zhengmao Ye, Hideo Miyake, Maki Tatsumi, Shigenori Nishimura, Yasunori Nitta

J. Biochem. 雑誌   135 ( 3 )   355 - 363   2004.03

Crystal Structure of a Catalytic Site Mutant of β-Amylase from Bacillus cereus var. mycoides Cocrystallized with Maltopentaose Reviewed

Hideo Miyake, Genji Kurisu, Masami Kusunoki, Shigenori Nishimura, Shinichi Kitamura, Yasunori Nitta

Biochemistry 雑誌   42 ( 19 )   5574 - 5581   2003.05

Catalytic Mechanism of β-Amylase from Bacillus cereus var. mycoides: Chemical Rescue of Hydrolytic Activity for a Catalytic Site Mutant(Glu367- Reviewed

Hideo Miyake, Chikako Otsuka, Shigenori Nishimura, Yasunori Nitta

J. Biochem. 雑誌   131 ( 4 )   587 - 591   2002.04

Conformation analysis of eel calcitonin--comparison with the conformation of elcatonin.

Ogawa K, Nishimura S, Uchiyama S, Kobayashi K, Kyogoku Y, Hayashi M, Kobayashi Y.

Eur. J. Biochem. 雑誌   257 ( 2 )   1998.10

Promotion of polypeptide folding by interactions with Asn-Glycans.

Kimura N, Uchida M, Nishimura S, Yamaguchi H.

J. Biochem 雑誌   124 ( 4 )   1998.10

Oxidative refolding of bovine pancreatic RNases A and B promoted by Asn-glycans Reviewed

Nishimura I, Uchida M, Inohana Y, Setoh K, Daba K, Nishimura S, Yamaguchi H.

J. Biochem. 雑誌   123 ( 3 )   1998.03

Maltal binding mechanism and a role of the mobile loop of soybean beta-amylase. Reviewed

Kunikata T, Nishimura S, Nitta Y.

Biosci Biotechnol Biochem. 雑誌   60 ( 7 )   1996.07

Conformational analysis of elcationin in solution Reviewed

Ogawa K, Nishimura S, Doi M, Kyogoku Y, Hayashi M, Kobayashi Y.

Eur. J. Biochem. 雑誌   222 ( 2 )   1994.06

Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by H-NMR and distance geometry Reviewed

Sato A, Nishimura S, Ohkubo T, Kyogoku Y, Koyama S, Kobayashi M, Yasuda T, Kobayashi Y

Int. J. Peptide Protein Res. 雑誌   41 ( 5 )   1993.05

H-NMR Assingment and Secondary Structure of Human Insulin-Like Growth Factor-I (IGF-I) in Solution Reviewed

Sato A, Nishimura S, Ohkubo T, Kyogoku Y, Koyama S, Kobayashi M, Yasuda T, Kobayashi Y

J. Biochem. 雑誌   111 ( 4 )   1992.04

Solution conformation of endothelin determined by means of H-NMR spectroscopy and distance geometry calculations Reviewed

Haruhiko Tamaoki, Yuji Kobayashi, Shigenori Nishimura, Tadayasu Ohkubo, Yoshimasa Kyogoku, Kiichiro Nakajima, Shin-ichiro Kumagaye, Terutoshi Kimura, Shumpei Sakakibara

Protein Engineering 雑誌   4 ( 5 )   1991.06

A new alpha-helical motif in membrane active peptides.

Kobayashi Y1, Sato A, Takashima H, Tamaoki H, Nishimura S, Kyogoku Y, Ikenaka K, Kondo T, Mikoshiba K, Hojo H, Aimoto S, Moroder L.

Neurochemistry International 雑誌   18 ( 4 )   1991.03

リポカリン型プロスタグランジンD合成酵素の多量体化による腫瘍標的ナノキャリアの開発

吉田 はるな, 下地 真広, 古田 航祐, 大久保 理奈, 西村 重徳, 乾 隆

日本生化学会大会プログラム・講演要旨集  2020.09  (公社)日本生化学会

リポカリン型プロスタグランジンD合成酵素の多量体化による腫瘍組織特異的ナノキャリアの開発

吉田 はるな, 下地 真広, 古田 航祐, 大久保 理奈, 田代 朝弓, 中辻 匡俊, 西村 重徳, 乾 隆

日本DDS学会学術集会プログラム予稿集  2020.08  日本DDS学会

Crystal structure of dog allergen Can f 1 Domestic conference

Keisuke Suda, Haruka Muroya, Yuma Fukutomi, Shigenori Nishimura, Osamu Ishibashi, Takashi Inui

第20回日本蛋白質科学会年会  2020.07 

微生物由来耐熱性β-アミラーゼの性質とX線結晶構造解析

田中 真奈, 西村 重徳, 谷 修治, 炭谷 順一, 川口 剛司

日本生物工学会大会講演要旨集  2019.08  (公社)日本生物工学会

低アレルゲン化ワクチンを用いたアレルゲン免疫療法によるイヌアレルギー治療への挑戦

2017

エキソ型α-アミラーゼの基質認識と糖転移反応の分子基盤

2014

GMP reductaseを標的とした新規アフリカ睡眠病治療薬の開発

2013

生命機能化学研究プレゼンテーション

2023   Intensive lecture   Graduate school

バイオインフォマティクス基礎実習

2023   Weekly class   Undergraduate

酵素化学

2023   Weekly class   Undergraduate

バイオインフォマティクス特論

2023     Graduate school

生命機能化学概論

2022   Weekly class   Undergraduate

生命機能化学研究プレゼンテーション

2022   Intensive lecture   Graduate school

生物物理化学実験

2022   Weekly class   Undergraduate

酵素化学

2022   Weekly class   Undergraduate

食品衛生学実習

2022   Practical Training   Undergraduate

Laboratory Chemistry

2021   Practical Training  

Enzyme Chemistry

2021    

General Principles of Applied Biological Chemistry

2021    

Laboratory : Biophysical Chemistry

2021   Practical Training