Updated on 2024/11/06

写真a

 
NAKAJIMA Takayuki
 
Organization
Graduate School of Veterinary Science Department of Veterinary Science Associate Professor
School of Veterinary Science Department of Veterinary Science
Title
Associate Professor
Affiliation
Institute of Veterinary Science

Position

  • Graduate School of Veterinary Science Department of Veterinary Science 

    Associate Professor  2022.04 - Now

  • School of Veterinary Science Department of Veterinary Science 

    Associate Professor  2022.04 - Now

Degree

  • 博士(獣医学) ( Others )

Research Areas

  • Life Science / Veterinary medical science  / 基礎獣医学•基礎畜産学

Awards

  • Best poster presentation

    2024.10   Asian association of veterinary anatomists   Functional significance of global cerebral ischemia-induced TGF-β signaling in the rat hippocampus

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    Country:Philippines

Papers

  • Oxygen-glucose deprivation-induced glial cell reactivity in the rat primary neuron-glia co-culture Reviewed

    Inoue M, Tanida T, Kondo T, Takenaka S, Nakajima T.

    J Vet Med Sci.   85 ( 8 )   2023.06

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    Repository URL: http://hdl.handle.net/10466/0002001084

  • The expression and phosphorylation of SMAD3 protein in microglia and astrocytes of the rat hippocampus after transient global cerebral ischemia Reviewed

    Takayuki Nakajima, Yuki Tanaka, Yusuke Takahashi, Tomohiro Kondo, Shigeo Takenaka

    J. Chem. Neuroanat.   125   2022.08

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    Authorship:Lead author, Corresponding author   International / domestic magazine:International journal  

    DOI: 10.1016/j.jchemneu.2022.102146.

  • Changes in Smad1/5/9 expression and phosphorylation in astrocytes of the rat hippocampus after transient global cerebral ischemia Reviewed

    Takayuki Nakajima, Yuji Kunieda, Yusuke Takahashi , Yuki Tanaka, Tomohiro Kondo, Shigeo Takenaka

    J. Chem. Neuroanat. 雑誌   113   2021.03

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    Kind of work:Joint Work  

  • The cytotoxicity and molecular mechanisms of the Clostridium perfringens NetB toxin Reviewed

    AKM Azharul ISLAM, Mitsuki NAKATAN, Takayuki NAKAJIMA, Tomoko KOHDA, Masafumi MUKAMOTO

    J. Vet. Med. Sci. 雑誌   83   187 - 194   2021.02

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    Kind of work:Joint Work  

  • Distribution of Smad mRNA and proteins in the rat brain Reviewed

    Nakajima T, Hata R, Kunieda Y, Kondo T

    J Chem Neuroanat 雑誌 Elsevier   90   11 - 39   2018.07

  • Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus) Reviewed

    Kondo T, Yoshida S, Nagai H, Takeshita A, Mino M, Morioka H, Nakajima T, Kusakabe KT, Okada T

    J Vet Sci 雑誌   19 ( 4 )   505 - 511   2018.06

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    Kind of work:Joint Work  

  • Proteomic analysis of the hippocampus in naïve and ischemic-preconditioned rat.

    Nakajima T, Hata R, Kondo T, Takenaka S.

    J. Neurol. Sci. 雑誌   358 ( 1-2 )   158 - 171   2015.08

  • Temporal and regional patterns of Smad activation in the rat hippocampus following global ischemia Reviewed

    Takayuki Nakajima, Masafumi Yanagihara, Hideki Nishii

    Journal of Neurological Sciences Elsevier   337 ( 1-2 )   25 - 37   2014.02

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    Kind of work:Joint Work  

  • Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium. Reviewed

    Ogawa K, Takemoto N, Ishii M, Pasquale EB, Nakajima T.

    Histochem. Cell Biol. 雑誌   136   617 - 636   2011.12

  • Complementary expression of EphB receptors and ephrin-B ligand in the pyloric and duodenal epithelium of adult mice. Reviewed

    Ishii M, Nakajima T, Ogawa K.

    Histochem. Cell Biol. 雑誌   136   345 - 356   2011.12

  • EphB signaling inhibits gap junctional intercellular communication and synchronized contraction in cultured cardiomyocytes. Reviewed

    Ishii M, Mueller I, Nakajima T, Pasquale EB, Ogawa K.

    Basic Res. Cardiol. 雑誌   106   1057 - 1068   2011.11

  • Ischemic preconditioning attenuates of ischemia-induced degradation of spectrin and tau: implications for ischemic tolerance. Reviewed

    Nakajima T, Ochi S, Oda C, Ishii M, Ogawa K.

    Neurol. Sci. 雑誌   11   229 - 239   2011.04

  • Induction of neurite outgrowth by alpha-phenyl-N-tert-butylnitrone through nitric oxide release and Rsa-ERK pathway in PC12 Reviewed

    Yasui H, Inanami O, Asanuma T, Iizuka D, Nakajima T, Kon Y, Matsuda A, Kuwabara M.

    Free. Radic. Res. 雑誌   44   645 - 654   2010.06

  • Effective and steady differentiation of a clonal derivative of P19CL6 embryonal carcinoma cell line into beating cardiomyocytes Reviewed

    Mueller I, Kobayashi R, Nakajima T, Ishii M, Ogawa K.

    J. Biomed. Biotechnol. 雑誌   2010.03

  • Treatment combining X-irradiation and a ribonucleoside anticancer drug, TAS106, effectively suppresses the growth of tumor cells transplanted in mice. Reviewed

    Yasui H, Inanami O, Asanuma T, Iizuka D, Nakajima T, Kon Y, Matsuda A, Kuwabara M.

    Int J Radiat Oncol Biol Phys 雑誌   68   218 - 228   2007.04

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    Kind of work:Joint Work  

  • Changes in cardiovascular function on treatment of inhibitor of apoptotic signal transduction pathways in left ventricular remodeling after myocardial infarction. Reviewed

    Saitoh T, Nakajima T, Takahashi T, Kawahara K.

    Cardiovascular pathology 雑誌   15   35 - 46   2006.05

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    Kind of work:Joint Work  

  • Dual inhibition of protein phosphatase-1/2A and calpain rescues nerve growth factor-differentiated PC12 cells from oxygen-glucose deprivation-induced cell death Reviewed

    Nakajima, T. Wakasa, T. Okuma, Y. Inanami, O. Nomura, Y. Kuwabara, M. Kawahara, K.

    Journal of Neuroscience Research 雑誌   83   459 - 468   2006.02

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    Kind of work:Joint Work  

  • EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases. Reviewed

    Ogawa K, Wada H, Okada N, Harada I, Nakajima T, Pasquale E, Tsuyama S.

    Journal of Cell Science 雑誌   119   559 - 570   2006.02

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    Kind of work:Joint Work  

  • Ischemia/reperfusion-induced death of cardiac myocytes: possible involvement of nitric oxide in the coordination of ATP supply and demand during ischemia Reviewed

    Kawahara, K. Hachiro, T. Yokokawa, T. Nakajima, T. Yamauchi, Y. Nakayama, Y.

    Journal of Molecular Cell Cardiology 雑誌   40   35 - 46   2006.01

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    Kind of work:Joint Work  

  • Functional significance of the preconditioning-induced down-regulation of glutamate transporter GLT-1 in neuron/astrocyte Reviewed

    Kosugi, T. Kawahara, K. Yamada, T. Nakajima, T. Tanaka, M.

    Neurochemical Research 雑誌   30   1109 - 1116   2005.09

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    Kind of work:Joint Work  

  • Reversed operation of astrocytic glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocyte co-cultures Reviewed

    Kawahara K, Kosugi T, Tanaka M, Nakajima T, Yamada T

    Glia 雑誌   49 ( 3 )   349 - 359   2005.02

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    Kind of work:Joint Work  

  • NADPHオキシダーゼ活性化機構とウシ分娩後の好中球機能低下 Reviewed

    稲波 修,脇 研二,山盛 徹,浅沼武敏,中島崇行,永幡 肇,桑原幹典

    獣医生化学 雑誌   41   1 - 13   2004.11

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    Kind of work:Joint Work  

  • Intercellular synchronization of intracellular Ca^<2+> oscillation in cultured cardiac myocytes Reviewed

    104 ( 429 )   41 - 44   2004.11

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    Kind of work:Joint Work  

  • Ouabain-induced reversal of astrocytic GLT-1 crusial to neuronal death in neuron/astrocyte co-cultures Reviewed

    Tanaka, M. Kawahara, K. Hosoya, R. Kosugi, T. Nakajima, T. Yamada, T.

    Neuroscience Research Communication 雑誌   35   150 - 163   2004.10

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    Kind of work:Joint Work  

  • Preconditioning prevents ischemia-induced neuronal death through persistent Akt activation in the penumbra region of the rat brain Reviewed

    Nakajima T, Iwabuchi S, Miyazaki H, Okuma Y, Kuwabara M, Nomura Y, Kawahara K

    J. Vet. Med. Sci. 雑誌   66   521 - 527   2004.05

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    Kind of work:Joint Work  

  • Nitric oxide produced during ischemia is toxic but crucial to preconditioning-induced ischemic tolerance of neurons in culture Reviewed

    Kawahara K, Yanoma J, Tanaka M, Nakajima T, Kosugi T

    Neurochem. Res. 雑誌   29   797 - 804   2004.04

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    Kind of work:Joint Work  

  • Regulation of cell metabolism of cardiac myocytes by enhanced production of nitric oxide during ischemia Reviewed

    103 ( 730 )   7 - 11   2004.03

  • Distribution of protein gene product 9.5-immunopositive and NADPH-diaphorase-positive neurons in the common marmoset (Callithrix jacchus) accessory olfactory bulb Reviewed

    Nakajima T, Tanioka Y, Taniguchi K

    J. Vet. Med. Sci. 雑誌   65   1307 - 1311   2003.12

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    Kind of work:Joint Work  

  • Ca2+-dependent and caspase-3-independent apoptosis caused by damage in Golgi apparatus due to 2,4,5,7-tetrabromorhodamine 123 bromide-induced photodynamic effects Reviewed

    Ogata M, Inanami O, Nakajima M, Nakajima T, Hiraoka W, Kuwabara M

    Photochem. Photobiol. 雑誌   78   241 - 247   2003.09

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    Kind of work:Joint Work  

  • Possible involvement of apoptotic death of myocytes in left ventricular remodeling after myocardial infarction Reviewed

    Saito T, Nakajima T, Kawahara K

    Jpn. J. Physiol. 雑誌   53   247 - 252   2003.06

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    Kind of work:Joint Work  

  • Astrocytic glutamate transporter GLT-1 crucial for the survival of neurons in neuron/astrocyte mixed cultures Reviewed

    103 ( 133 )   5 - 10   2003.06

  • Selective blockade of astrocytic glutamate transporter GLT-1 with dihydrokainate prevents neuronal death during ouabain treatment of astrocyte/neuron co-cultures Reviewed

    Kawahara K, Hosoya R, Sato H, Tanaka M, Nakajima T, Iwabuchi, S

    Glia 雑誌   40 ( 3 )   337 - 349   2002.12

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    Kind of work:Joint Work  

  • Relationship between the activation of cyclic AMP responsive element binding protein and ischemic tolerance in the penumbra region of rat cerebral cortex Reviewed

    Nakajima T, Iwabuchi S, Miyazaki H, Okuma Y, Inanami O, Kuwabara M, Nomura Y, Kawahara K

    Neurosci. Lett. 雑誌   331   13 - 16   2002.10

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    Kind of work:Joint Work  

  • Possible involvement of nitric oxide in the ischemic preconditionig of neurons in neuron/astrocyte co-cultures Reviewed

    17   321 - 322   2002.09

  • Programmed cell death in left ventricular remodeling after myocardial infarction Reviewed

    17   161 - 162   2002.09

  • Astrocytic glutamate transporter GLT-1 crucial for the survival of neurons in neuron/astrocyte mixed cultures Reviewed

    102 ( 137 )   1 - 4   2002.06

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    Kind of work:Joint Work  

  • Increased resistance to nitric oxide cytotoxicity associated with differentiation of neuroblastoma-glioma hybrid (NG108-15) cells Reviewed

    Kawahara K, Saito M, Nakajima T, Sato H, Tanaka M, Tojima T, Ito E

    Free Radic. Res. 雑誌   36   545 - 554   2002.05

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    Kind of work:Joint Work  

  • Functional roles of glial glutamate transporter GLT-1 at ischemic condition in neuron-glia mixed culture Reviewed

    100 ( 685 )   77 - 82   2001.03

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    Kind of work:Joint Work  

  • Immunohistochemical and enzyme-histochemical study on the accessory olfactory bulb of the dog Reviewed

    Nakajima T, Sakaue M, Kato M, Saito S, Ogawa K, Taniguchi K

    Anat Rec 雑誌 Willey-Liss   252   339 - 402   1998.11

  • Lectin-binding patterns in the olfactory epithelium and vomeronasal organ of the common marmoset Reviewed

    Nakajima T, Shiratori K, Ogawa K, Tanioka Y, Taniguchi K

    J. Vet. Med. Sci 雑誌   60   1005 - 1011   1998.09

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    Kind of work:Joint Work  

  • Immunohistochemical demonstration of mammalian- and FMRF amide-like peptides in the gut innervation and endocrine cells of the wild silkmoth (Antheraea yamamai) (Lepidoptera: Saturniidae) during diapause and post-diapause of pharate first-instar larvae Reviewed

    An Y, Nakajima T, Suzuki K

    Eur. J. Entomol. 雑誌   95   185 - 196   1998.05

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    Kind of work:Joint Work  

  • Immunoreactivity of protein gene product 9.5 (PGP9.5) in the developing hamster olfactory bulb Reviewed

    Nakajima T, Murabayashi C, Ogawa K, Taniguchi K

    Anat. Rec. 雑誌   250   238 - 244   1998.02

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    Kind of work:Joint Work  

  • Immunohistochemical and enzyme histochemical characteristics of short axon cells in the olfactory bulb of the golden hamster Reviewed

    Nakajima T, Okamura M, Ogawa K, Taniguchi K

    J. Vet. Med. Sci. 雑誌   58   903 - 908   1996.09

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    Kind of work:Joint Work  

  • 非放射性プローブを用いたin situ hybridization (ISH)法によるカルシトニンmRNA検出の最適条件の検討 Reviewed

    中島崇行,小川和重,谷口和之

    実験動物 雑誌   43   477 - 486   1994.10

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    Kind of work:Joint Work  

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Presentations

  • Functional significance of global cerebral ischemia-induced TGF-β signaling in the rat hippocampus International conference

    Tajkayuki Nakajima and Yusei Wada

    9th Asian Accosication of Veterynalry Anatomists  2024.10  Dept. of Basic veterinary sciences, College of veterinary medicine, Univ. of Phillipine

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    Presentation type:Poster presentation  

    Venue:Univ. of Phillipine  

  • 全脳虚血ラット海馬グリア細胞におけるTGF-β/Smadシグナルの活性とその役割 Domestic conference

    中島崇行、和田優生

    第129回日本解剖学会総会・全国学術集会  2024.03  琉球大学

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    Presentation type:Poster presentation  

    Venue:沖縄県那覇市  

  • 1. 全脳虚血ラット海馬グリア細胞におけるSmadの活性とその役割について Domestic conference

    中島崇行

    第31回日本病態生理学会  2022.08 

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    Presentation type:Oral presentation (general)  

    Venue:岐阜大学  

  • 全脳虚血後の海馬アストロサイトにおけるSmad1/5/9発現とリン酸化について Domestic conference

    田中 勇気、中島崇行

    第1回獣医解剖アカデミア  2021.03 

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    Presentation type:Poster presentation  

  • 全脳虚血後のラット海馬におけるSmad1/5/8の発現とその活性について Domestic conference

    中島 崇行、田中 勇気、竹中 重雄

    第163回日本獣医学会学術集会  2020.09 

  • 全脳虚血後の海馬グリア細胞におけるSmadの発現とその活性について Domestic conference

    中島 崇行、髙橋 勇祐、竹中 重雄

    第125回日本解剖学会  2020.03 

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    Presentation type:Poster presentation  

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Grant-in-Aid for Scientific Research

  • Functional significance of ischemia-induced TGF-beta/Smad signaling in glial cells

    Grant-in-Aid for Scientific Research(C)  2026

  • 5/6腎臓摘出母体から生まれた子の成長に関する研究:新たな子癇前症モデルの開発

    Grant-in-Aid for Scientific Research(C)  2025

  • Functional significance of ischemia-induced TGF-beta/Smad signaling in glial cells

    Grant-in-Aid for Scientific Research(C)  2025

  • 全脳虚血誘導性TGF-β/Smadシグナルのグリア細胞における役割の解明

    Grant-in-Aid for Scientific Research(C)  2024.04

  • 5/6腎臓摘出母体から生まれた子の成長に関する研究:新たな子癇前症モデルの開発

    Grant-in-Aid for Scientific Research(C)  2024

  • Functional significance of ischemia-induced TGF-beta/Smad signaling in glial cells

    Grant-in-Aid for Scientific Research(C)  2024

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Charge of on-campus class subject

  • 獣医組織学実習

    2024   Weekly class   Undergraduate

  • 獣医解剖組織学B

    2024   Intensive lecture   Undergraduate

  • 獣医解剖組織学B

    2024   Weekly class   Undergraduate

  • 小動物基礎臨床実習

    2024   Intensive lecture   Undergraduate

  • 獣医組織学

    2024   Weekly class   Undergraduate

  • 獣医解剖学B

    2024   Intensive lecture   Undergraduate

  • 獣医解剖学A

    2024   Intensive lecture   Undergraduate

  • 統合生体学特別講義A

    2024   Intensive lecture   Graduate school

  • 獣医科学英語演習

    2024   Intensive lecture   Undergraduate

  • Special Lecture: Integrated Structural Biosciences A

    2021    

  • Pathological Animal Model Science

    2021    

  • Practice in Veterinary Histology

    2021   Practical Training  

  • Biology A

    2021    

  • Fundamental Experiments of Biology

    2021   Practical Training  

  • Practice in Veterinary Anatomy

    2021   Practical Training  

  • Veterinary Anatomy B

    2021    

  • Veterinary Anatomy A

    2021    

  • Veterinary Histology

    2021    

  • Basic clinical practices

    2021   Practical Training  

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Faculty development activities

  • 2020

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    獣医組織学第8版 麻生久、尼崎肇、市居修、市原伸恒、植田弘美、中島崇行、小川和重

  • 2019

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    獣医解剖・組織・発生学第2版 市居修、植田弘美、大石元治、中島崇行、小川和重 学窓社

  • 2019

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    獣医発生学第2版 金井克晃、真鍋昇、九郎丸正道、小川和重、中島崇行 学窓社

Number of instructed thesis, researches

  • 2023

    Number of instructed the graduation thesis:Number of graduation thesis reviews:2

  • 2022

    Number of instructed the graduation thesis:Number of graduation thesis reviews:2

Academic Activities

  • Molecular Neurobiology

    Role(s): Peer review

    Springer Science+Business Media  2024.04

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    Type:Peer review 

  • Neurochemical Research

    Role(s): Peer review

    Springer Science+Business Media  2024.03

  • The Journal of Veterinary Medical Science

    Role(s): Peer review

    Japanese Society of Veterinary Science  2024.03

  • Cytotechnology

    Role(s): Peer review

    Springer Nature B.V.  2024.03

  • Molecular Neurobiology

    Role(s): Peer review

    Springer Science+Business Media  2024.02 - 2024.03

  • Cell Communication and Signaling

    Role(s): Peer review

    2024.01 - 2024.03

  • Neurochemical Research

    Role(s): Peer review

    Springer Science+Business Media  2024.01

  • Neurochemical Research

    Role(s): Peer review

    Springer Science+Business Media  2023.09

  • Journal of Neurochemistry

    Role(s): Peer review

    Willey  2023.08 - 2024.01

  • Neurochemical Research

    Role(s): Peer review

    Springer Science+Business Media  2023.08

  • The Journal of Veterinary Medical Science

    Role(s): Peer review

    Japanese Society of Veterinary Science  2023.06

  • Journal of Toxicologic Pathology

    Role(s): Peer review

    Japanese Society of Toxicologic Pathology  2023.01

  • NeuroMolecular Medicine

    Role(s): Peer review

    Springer Science+Business Media  2022.10

  • Neurochemical Research

    Role(s): Peer review

    Springer Science+Business Media  2022.06

  • Journal of Toxicologic Pathology

    Role(s): Peer review

    Japanese Society of Toxicologic Pathology  2022.06 - 2022.07

  • BMC Neuroscience

    Role(s): Peer review

    BMC  2022.03 - 2022.04

  • Neurochemistry International

    Role(s): Peer review

    Elsevier B.V.  2022.03 - 2022.06

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Foreigner acceptance

  • 2016

    International Students :1