森永賞

2012.06   公益財団法人　森永奉仕会   胎児、新生児期におけるテストステロンサージの身体的発達における影響

Transport form and pathway from intestine to peripheral tissues and intestinal absorption and metabolism properties of oleamide Reviewed

Yasuyuki Kobayashi, Natsumi Watanabe, Reina Hiura, Mai Kubota, Kousuke Furuta, Keiichiro Sugimoto, Kaeko Murota, Eri Nakamura, Toshiki Matsuura, Kenji Kai, Takashi Inui, Tomoya Kitakaze, Naoki Harada, Ryoichi Yamaji*.

J. Agric. Food Chem.   70   15499 - 15508   2022.12

Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice Reviewed

Naoki Harada*, Keitaro Kubo, Teruaki Onishi, Tomoya Kitakaze, Tsuyoshi Goto, Hiroshi Inui, Ryoichi Yamaji.

J. Biol. Chem.   298 ( 12 )   102619   2022.12

Carotenoid transporter CD36 expression depends on hypoxia-inducible factor-1α in mouse soleus muscles Reviewed

Tomoya Kitakaze, Takashi Sugihira, Hiromichi Kameyama, Asami Maruchi, Yasuyuki Kobayashi, Naoki Harada, and Ryoichi Yamaji*.

J. Clin. Biochem. Nutr.   71 ( 2 )   112 - 131   2022.09

Dietary oleamide attenuates obesity induced by housing mice in small cages Reviewed

Yasuyuki Kobayashi, Mai Kubota, Keiichiro Sugimoto, Tomoya Kitakaze, Naoki Harada, Ryoichi Yamaji*.

Biosci. Biotechnol. Biochem.   86 ( 8 )   1095 - 1105   2022.07

Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid Reviewed International coauthorship

Naoki Harada*, Yumi Arahori, Mai Okuyama, Paula B. Luis, Akil I. Joseph, Tomoya Kitakaze, Naoki Goshima, Claus Schneider, Hiroshi Inui, and Ryoichi Yamaji.

Biochem. Biophys. Res. Commun. 雑誌   595   41 - 46   2022.03

Identification of G-protein coupled receptor 55 (GPR55) as a target of curcumin Reviewed International coauthorship

Naoki Harada*, Mai Okuyama, Yoshiaki Teraoka, Yumi Arahori, Yoh Shinmori, Hiroko Horiuchi, Paula B. Luis, Akil I. Joseph, Tomoya Kitakaze, Shigenobu Matsumura, Tohru Hira, Norio Yamamoto, Takashi Iuni, Naoki Goshima, Claus Schneider, Hiroshi Inui, and Ryoichi Yamaji.

npj Sci. Food   6   4   2022.01

Exopolysaccharides from a Scandinavian fermented milk viili increase butyric acid and Muribaculum members in the mouse gut Reviewed

Takuya Yamane*, Satoshi Handa, Momoko Imai, Naoki Harada, Tatsuji Sakamoto, Tetsuo Ishida, Takenori Nakagaki, Yoshihisa Nakano.

Food Chem. Mol. Sci. 雑誌   3   2021.12

Oleamide rescues tibialis anterior muscle atrophy of mice housed in small cages Reviewed

Yasuyuki Kobayashi, Natsumi Watanabe, Tomoya Kitakaze, Takeshi Izawa, Keiichiro Sugimoto, Kenji Kai, Naoki Harada, and Ryoichi Yamaji*.

Br. J. Nutr. 雑誌   126 ( 4 )   481 - 491   2021.08

Aronia juice supplementation inhibits lipid accumulation in both normal and obesity model mice Reviewed

Takuya Yamane*, Momoko Imai, Satoshi Handa, Naoki Harada, Ryoichi Yamaji, Tatsuji Sakamoto, Tetsuo Ishida, Hiroshi Inui, Takenori Nakagaki, and Yoshihisa Nakano.

PharmaNutrition 雑誌   14   2020.12

Effects of caffeine and chlorogenic acid on nonalcoholic steatohepatitis in mice induced by choline-deficient, L-amino acid-defined, high-fat diet Reviewed

Erdenetsogt Dungubat, Shiori Watabe, Arisa Togashi-Kumagai, Masato Watanabe, Yasuyuki Kobayashi, Naoki Harada, Ryoichi Yamaji, Toshio Fukusato, Galtsog Lodon, Badamjav Sevjid, Yoshihisa Takahashi*.

Nutrients 雑誌   12   2020.12

Relationship between gut environment, feces-to-food ratio, and androgen deficiency-induced metabolic disorders Reviewed

Naoki Harada*, Yukari Minami, Kazuki Hanada, Ryo Hanaoka, Yasuyuki Kobayashi, Takeshi Izawa, Takashi Sato, Shigeaki Kato, Hiroshi Inui, and Ryoichi Yamaji.

Gut Microbes 雑誌   12 ( 1 )   2020.11

Effects of low ethanol consumption on nonalcoholic steatohepatitis in mice Reviewed

Yoshihisa Takahashi*, Shiori Watabe, Arisa Togashi-Kumagai, Masato Watanabe, Erdenetsogt Dungubat, Hiroyuki Kusano, Yasuyuki Kobayashi, Naoki Harada, Ryoichi Yamaji, Keiichiro Sugimoto, Toshio Fukusato.

Alcohol 雑誌   87   51 - 61   2020.09

Biological activity of pseudovitamin B12 on cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase in mammalian cultured COS-7 cells Reviewed

Tomohiro Bito*, Mariko Bito, Tomomi Hirooka, Naho Okamoto, Naoki Harada, Ryoichi Yamaji, Yoshihisa Nakano, Hiroshi Inui, and Fumio Watanabe.

Molecules 雑誌   25   2020.07

β-Cryptoxanthin improves p62 accumulation and muscle atrophy in the soleus muscle of senescence-accelerated mouse-prone 1 mice Reviewed

Mari Noguchi, Tomoya Kitakaze, Yasuyuki Kobayashi, Katsuyuki Mukai, Naoki Harada, and Ryoichi Yamaji*.

Nutrients 雑誌   12   2020.07

Food texture affects glucose tolerance by altering pancreatic β-cell function in mice consuming high-fructose corn syrup Reviewed

Naoki Harada*, Masayuki Nomura, Yasuhiro Yoda, Shigenobu Matsumura, Hiroshi Inui, and Ryoichi Yamaji.

PLoS One 雑誌   15 ( 5 )   2020.05

Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice Reviewed

Naoki Harada*, Kazuki Hanada, Yukari Minami, Tomoya Kitakaze, Yoshiyuki Ogata, Hayato Tokumoto, Takashi Sato, Shigeaki Kato, Hiroshi Inui, and Ryoichi Yamaji.

Am. J. Physiol. Endocrinol. Metab. 雑誌   318   E525 - E537   2020.04

Extracellular transglutaminase 2 induces myotube hypertrophy through G protein-coupled receptor 56 Reviewed

Tomoya Kitakaze, Miki Yoshikawa, Yasuyuki Kobayashi, Naohiro Kimura, Naoki Goshima, Takahiro Ishikawa, Yoshiyuki Ogata, Yoko Yamashita, Hitoshi Ashida, Naoki Harada, and Ryoichi*

Biochim. Biophys. Acta – Mol. Cell Res. 雑誌   1867   2020.02

Effects of crystalline and amorphous forms of paramylon from Euglena gracilis on the development of water-immersion restraint stress-induced gastric ulcer Reviewed

Misa Ogushi*, Momoko Imai, Minako Yoshizawa, Kengo Suzuki, and Naoki Harada.

Food Sci. Technol. Res. 雑誌   26 ( 1 )   153 - 158   2020.01

Tomatidine, a steroidal alkaloid from green tomatoes, reduces palmitate-induced lipid accumulation by activating AMPK via vitamin D receptor-mediated signaling in human HepG2 hepatocytes Reviewed

Hikari Kusu, Hiroki Yoshida, Michiko Kudo, Mai Okuyama, Naoki Harada, Kentaro Tsuji-Naito, and Mitsugu Akagawa*.

Mol. Nutr. Food Res.   63 ( 22 )   2019.12

Fetal androgen signaling defects affect pancreatic β-cell mass and function, leading to glucose intolerance in high-fat diet-fed male rats Reviewed

Naoki Harada*, Yusuke Yotsumoto, Takahiro Katsuki, Yasuhiro Yoda, Tatsuya Masuda, Masayuki Nomura, Nobuaki Shiraki, Hiroshi Inui, and Ryoichi Yamaji.

Am. J. Physiol. Endocrinol. Metab. 雑誌   317   E731 - E741   2019.11

5-Hydroxy-7-methoxyflavone derivatives from Kaempferia parviflora induce skeletal muscle hypertrophy Reviewed

Shintaro Ono, Naoki Yoshida, Daisuke Maekawa, Tomoya Kitakaze, Yasuyuki Kobayashi, Takehiro Kitano, Takanori Fujita, Hirotaka Okuwa-Hayashi, Naoki Harada, Yoshihisa Nakano, and Ryoichi Yamaji*.

Food Sci. Nutr. 雑誌   7   312 - 321   2019.01

Role of androgens in energy metabolism affecting on body composition, metabolic syndrome, type 2 diabetes, cardiovascular disease, and longevity: Lessons from a meta-analysis and rodent studies.

Naoki Harada*.

Biosci. Biotechnol. Biochem. 雑誌 Taylor Francis   82 ( 10 )   1667 - 1682   2018.10

Lactoferrin promotes murine C2C12 myoblast proliferation and differentiation, and myotube hypertrophy

Tomoya Kitakaze, Meiku Oshimo, Yasuyuki Kobayashi, Mizuyuki Ryu, Yasushi A. Suzuki, Hiroshi Inui, Naoki Harada, and Ryoichi Yamaji*.

Mol. Med. Rep. 雑誌   17   5912 - 5920   2018.04

Androgen signaling expands β-cell mass in male rats and β-cell androgen receptor is degraded under high-glucose conditions Reviewed

Naoki Harada*, Yasuhiro Yoda, Yusuke Yotsumoto, Tatsuya Masuda, Yuji Takahashi, Takahiro Katsuki, Kenji Kai, Nobuaki Shiraki, Hiroshi Inui, and Ryoichi Yamaji.

Am. J. Physiol. Endocrinol. Metab. 雑誌   314   E274 - E286   2018.03

Theophylline suppresses interleukin-6 expression by inhibiting glucocorticoid receptor signaling in pre-adipocytes. Reviewed

Takakazu Mitani, Tomohide Takaya, Naoki Harada, Shigeru Katayama*, Ryoichi Yamaji, Soichiro Nakamura, Hitoshi Ashida.

Arch. Biochem. Biophys. 雑誌 Elsevier   646   98 - 106   2018.03

Stereoselective effects of lactate enantiomers on the enhancement of 3T3-L1 adipocyte differentiation Reviewed

Naoki Harada*, Ito Hirano, Hiroshi Inui, and Ryoichi Yamaji.

Biochem. Biophys. Res. Commun. 雑誌   498   105 - 110   2018.03

Lactoferrin induces tropoelastin expression by activating the lipoprotein receptor-related protein 1-mediated phosphatidylinositol 3-kinase/Akt pathway in human dermal fibroblasts Reviewed

Mizuyuki Ryu, Asuka Nogami, Tomoya Kitakaze, Naoki Harada, Yasushi A Suzuki, and Ryoichi Yamaji*.

Cell Biol. Int. 雑誌   41   1325 - 1334   2017.12

S-Equol activates cAMP signaling at the plasma membrane of INS-1 pancreatic β-cells and protects against streptozotocin-induced hyperglycemia by increasing β-cell function in male mice

Hiroko Horiuchi, Atsuko Usami, Rie Shirai, Naoki Harada*, Shinichi Ikushiro, Toshiyuki Sakaki, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji.

J. Nutr. 雑誌   147 ( 9 )   1631 - 1639   2017.09

Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor β and increases skeletal muscle mass in young female mice Reviewed

Masahiro Ogawa, Takehiro Kitano, Natsuha Kawata, Takashi Sugihira, Tomoya Kitakaze, Naoki Harada and Ryoichi Yamaji*.

J. Nutr. Biochem. 雑誌   49 ( 9 )   1631 - 1639   2017.08

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) aggregation causes mitochondrial dysfunction during oxidative stress-induced cell death

Masanori Itakura, Hidemitsu Nakajima*, Takeya Kubo, Akihiro Kaneshige, Naoki Harada, Takeshi Izawa, Yasu-Taka Azuma, Mitsuru Kuwamura, Ryoichi Yamaji, and Tadayoshi Takeuchi.

J. Biol. Chem. 著書   292 ( 11 )   4727 - 4742   2017.03

Hypogonadism alters cecal and fecal microbiota in male mice Reviewed

Naoki Harada*, Ryo Hanaoka, Kazuki Hanada, Takeshi Izawa, Hiroshi Inui, and Ryoichi Yamaji.

Gut Microbes 雑誌   7 ( 6 )   533 - 539   2016.11

Mogrol Derived from Siraitia grosvenorii Mogrosides Suppresses 3T3-L1 Adipocyte Differentiation by Reducing cAMP-Response Element-Binding Protein Phosphorylation and Increasing AMP-Activated Protein Kinase Phosphorylation Reviewed

Naoki Harada*, Mikako Ishihara, Hiroko Horiuchi, Yuta Ito, Hiromitsu Tabata, Yasushi A Suzuki, Yoshihisa Nakano, Ryoichi Yamaji, and Hiroshi Inui*.

PLoS ONE 雑誌   11 ( 9 )   2016.09

The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy Reviewed

Tomoya Kitakaze, Tomotaka Sakamoto, Takehiro Kitano, Naoki Inoue, Fumihito Sugihara, Naoki Harada, and Ryoichi Yamaji*.

Biochem. Biophys. Res. Commun. 雑誌   478 ( 3 )   2690 - 2699   2016.09

pVHL-mediated degradation of HIF-2αregulates estrogen receptor α expression in normoxic breast cancer cells Reviewed

Yasuki Higashimura, Tomoya Kitakaze, Naoki Harada, Hiroshi Inui, Yoshihisa Nakano, Ryoichi Yamaji*.

FEBS Lett. 雑誌 Wiley   590 ( 16 )   2690 - 2699   2016.08

Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice Reviewed

Naoki Harada*, Ryo Hanaoka, Hiroko Horiuchi, Tomoya Kitakaze, Takakazu Mitani, Hiroshi Inui, and Ryoichi Yamaji.

Sci. Rep. 雑誌 Nature publication group   6   2016.03

β-Carotene increases muscle mass and hypertrophy in the soleus muscle in mice Reviewed

Tomoya Kitakaze, Naoki Harada, Hidetaka Imagita, Ryoichi Yamaji*

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   61 ( 6 )   481 - 487   2015.12

Glyceraldehyde-3-phosphate dehydrogenase aggregates accelerate amyloid-βamyloidogenesis in Alzheimer disease Reviewed

Masanori Itakura, Hidemitsu Nakajima*, Takeya Kubo, Yuko Semi, Satoshi Kume, Shusaku Higashida, Akihiro Kaneshige, Mitsuru Kuwamura, Naoki Harada, Yasu-Taka Azuma, Ryoichi Yamaji, Takashi Inui, and Tadayoshi Takeuchi.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   290 ( 43 )   26072 - 26087   2015.10

Protein arginine metyltransferase 10 is required for androgen-dependent proliferation of LNCaP prostate cancer cells Reviewed

Naoki Harada*, Toshiki Takagi, Yoshihisa Nakano, Ryoichi Yamaji, and Hiroshi Inui.

Biosci. Biotechnol. Biochem. 雑誌 Taylor Francis   79 ( 9 )   1430 - 1437   2015.09

Autophagic degradation of the androgen receptor mediated by increased phosphorylation of p62 suppresses apoptosis in hypoxia Reviewed

Takakazu Mitani, Masato Minami, Naoki Harada, Hitoshi Ashida, and Ryoichi Yamaji*.

Cell. Signal. 雑誌   27   1994 - 2001   2015.07

Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic β-cells Reviewed

Naoki Harada*, Takahiro Katsuki, Yuji Takahashi, Tatsuya Masuda, Mariko Yoshinaga, Tetsuya Adachi, Takeshi Izawa, Mitsuru Kuwamura, Yoshihisa Nakano, Ryoichi Yamaji, and Hiroshi, Inui.

J. Cell. Biochem. 雑誌 Wiley   116 ( 6 )   998 - 1006   2015.06

Female-specific regulation of skeletal muscle mass by USP19 in young mice Reviewed

Masahiro Ogawa, Tomoya Kitakaze, Naoki Harada, and Ryoichi Yamaji*.

J. Endocrinol. 雑誌 Society for Endocrinology   225 ( 3 )   135 - 145   2015.06

Competitive and compensatory effects of androgen signaling and glucocorticoid signaling Reviewed

Naoki Harada*, Hiroshi Inui, and Ryoichi Yamaji.

Receptors Clin. Invest. 雑誌 Smart Science Technology   2 ( 3 )   2015.05

Inhibitory effects of Eucalyptus and Banaba leaf extracts on nonalcoholic steatohepatitis induced by a high-fructose/high-glucose diet in rats Reviewed

Yoshihisa Takahashi*, Keiichiro Sugimoto, Yurie Soejima, Arisa Kumagai, Tatsuki Koeda, Aiko Shojo, Kazuya Nakagawa, Naoki Harada, Ryoichi Yamaji, Hiroshi Inui, Toshikazu Yamanouchi, and Toshio Fukusato.

Biomed. Res. Int. 雑誌 Hindawi   2015   2015.04

Resveratrol inhibits hypoxia-inducible factor-1α-mediated androgen receptor signaling and represses tumor progression in castration-resistant prostate cancer Reviewed

Takakazu Mitani, Naoki Harada, Shinji Tanimori, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji*.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   60 ( 4 )   276 - 282   2014.10

S-Equol enantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells Reviewed

Hiroko Horiuchi, Naoki Harada*, Tetsuya Adachi, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   60 ( 4 )   291 - 296   2014.10

Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells Reviewed

Takakazu Mitani, Yuta Ito, Naoki Harada, Yoshihisa Nakano, Hiroshi Inui, Hitoshi Ashida, and Ryoichi Yamaji*

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   60 ( 2 )   122 - 128   2014.06

Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4´-amino-3,5-dihydroxy-trans-stilbene Reviewed

Yuta Ito, Takakazu Mitani, Naoki Harada, Atsushi Isayama, Shingi Tanimori, Shigeo Takenaka, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji*.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   59 ( 4 )   358 - 364   2013.09

Biochemical characterization of a GH53 endo-beta-1,4-galactanase and a GH35 exo-beta-1,4-galactanase from Penicillium chrysogenum Reviewed

Tatsuji Sakamoto*, Yuichi Nishimura, Yosuke Makino, Yoichi Sunagawa, and Naoki Harada.

Appl. Microbiol. Biotechnol. 雑誌 Supringer   97 ( 7 )   2895 - 2906   2013.04

The preventive effect of beta-carotene on denervation-induced soleus muscle atrophy in mice Reviewed

Masahiro Ogawa, Yoshihiro Kariya, Tomoya Kitakaze, Ryoichi Yamaji*, Naoki Harada, Tatsuji Sakamoto, Keisuke Hosotani, Yoshihisa Nakano, and Hiroshi Inui.

Brit. J. Nutr. 雑誌 Cambridge University Press   109   1349 - 1358   2013.04

Coordinated action of hypoxia-inducible factor-1alpa and beta-catenin in androgen receptor signaling Reviewed

Takakazu Mitani, Naoki Harada, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji*.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   287 ( 40 )   33594 - 33606   2012.09

Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostae cancer LNCaP cells Reviewed

Naoki Harada*, Kaoru Inoue, Ryoichi Yamaji, Yoshihisa Nakano, and Hiroshi Inui.

Cancer Sci. 雑誌 Wiley   103 ( 6 )   1022 - 1027   2012.06

Purification, characterization and gene cloning of two forms of a thermostable endo-xylanase from Streptomyces sp. SWU10 Reviewed

Warin Deesukon, Yuichi Nishimura, Naoki Harada, Tatsuji Sakamoto*, and Wasana Sukhumsirichart*.

Process Biochem. 雑誌 Elsevier   46   2255 - 2262   2011.12

Estrogens repress differentiation of skeletal muscle by increasing ubiquitin-specific peptidase 19 through estrogen receptor alpha Reviewed

Masahiro Ogawa, Ryoichi Yamaji*, Yasuki Higashimura, Naoki Harada, Hitoshi Ashida, Yoshihisa Nakano, and Hiroshi Inui.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   286 ( 48 )   41455 - 41465   2011.12

Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2a through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms Reviewed

Yasuki Higashimura, Takashi Terai, Ryoichi Yamaji*, Takakazu Mitani, Masahiro Ogawa, Naoki Harada, Hiroshi Inui, and Yoshihisa Nakano.

Biochem. Biophys. Res. Commun. 雑誌 Elsevier   413 ( 2 )   201 - 205   2011.09

Suppression of inducible ntric oxide synthase expression and amelioration of lipopolysaccharide-induced liver injury by polyphenolic compounds in eucalyptus globulus leaf extract Reviewed

Keiichiro Sugimoto, Sayaka Sakamoto, Kazuya Nakagawa, Shuichi Hayashi, Naoki Harada, Ryoichi Yamaji, Yoshihisa Nakano, and Hiroshi Inui*.

Food Chem. 雑誌 Elsevier   125   442 - 446   2011.03

Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells Reviewed

Yasuki Higashimura, Yoshito Nakajima, Ryoichi Yamaji*, Naoki Harada, Futoshi Shibasaki, Yoshihisa Nakano, and Hiroshi Inui.

Arch. Biochem. Biophys. 雑誌 Elsevier   509   2011.02

Inhibitory mechanisms of the transcriptional activity of androgen receptor by resveratrol: implication of DNA-binding and acetylation of the receptor Reviewed

Naoki Harada, Kiyotaka Atarashi, Yohei Murata, Ryoichi Yamaji*, Yoshihisa Nakano, and Hiroshi Inui.

J. Steroid Biochem. Mol. Biol. 雑誌 Elsevier   123 ( 41641 )   65 - 70   2011.01

Hypoxia enhances transcriptional activity of androgen receptor through hypoxia-inducible factor-1alpha in a low androgen environment Reviewed

Takakazu Mitani, Ryoichi Yamaji*, Yasuki Higashimura, Naoki Harada, Yoshihisa Nakano, and Hiroshi Inui.

J. Steroid Biochem. Mol. Biol. 雑誌 Elsevier   123 ( 41641 )   58 - 64   2011.01

Construction of a dominant negative form of human hypoxia-inducible factor-2alpha Reviewed

Yasuki Higashimura, Ryoichi Yamaji*, Naoki Harada, Motoyuki Nakao, Yoshihisa Nakano, and Hiroshi Inui.

Biosci. Biotechnol. Biochem. 雑誌 Japan Society for Bioscience, Biotechnology and Agrochemistry   74 ( 10 )   2100 - 2102   2010.10

Involvement of three glutamine tracts in human androgen receptor transactivation Reviewed

Naoki Harada, Takakazu Mitani, Yasuki Higashimura, Ryoichi Yamaji*, Kazuki Okamoto, Yoshihisa Nakano, and Hiroshi Inui.

J. Steroid Biochem. Mol. Biol. 雑誌 Elsevier   118 ( 41641 )   77 - 84   2010.09

A yeast bioassay for androgenic and anti-androgenic compounds based on the NH2- and COOH-terminal interaction of androen receptor Reviewed

Masahiro Ogawa, Ryoichi Yamaji*, Takakazu Mitani, Yohei Murata, Motoyuki Nakao, Naoki Harada, Yoshihisa Nakano, and Hiroshi Inui.

Biosci. Biotechnol. Biochem. 雑誌 Japan Society for Bioscience, Biotechnology and Agrochemistry   74 ( 9 )   1965 - 1968   2010.09

Potential use of bischofia javanica as an active ingredient of functional foods and cosmeceutical products possessing hyaluronidase, collagenase, tyrosinase and urease inhibitory effects Reviewed

Florin Barla, Asako Horinishi, Naoki Harada, Ryoichi Yamaji, Toshiki Enomoto*, Nobutaka Suzuki, Hisayuki Maenaka, Yoshihisa Nakano, and Hiroshi Inui.

Jpn. J. Compl. Alternative Med. 雑誌 The Japanese Society for Complementary and Alternative Medicine   7 ( 2 )   129 - 133   2010

Inhibitive effects of alkyl gallates on hyaluronidase and collagenase Reviewed

Florin Barla, Hayato Higashijima, Shingo Funai, Keiichiro Sugimoto, Naoki Harada, Ryoichi Yamaji, Tomoyuki Fujita, Yoshihisa Nakano, and Hiroshi Inui*.

Biosci. Biotechnol. Biochem. 雑誌 Japan Society for Bioscience, Biotechnology and Agrochemistry   73 ( 10 )   2335 - 2337   2009.10

Cobalamin deficiency results in an abnornal increase in L-methylmalonyl-CoA mutase expresseion in rat liver and COS-7 cells. Reviewed

Motoyuki Nakao, Shoko Hironaka, Naoki Harada, Tetsuya Adachi, Tomohiro Bito, Yukinori Yauta, Fumio Watanabe, Takumi Miura, Ryoichi Yamaji, Hiroshi Inui*, and Yoshihisa Nakano.

Br. J. Nutr. 雑誌 Cambridge University Press   101   484 - 490   2009.09

ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor Reviewed

Naoki Harada, Yuji Ohmori, Ryoichi Yamaji*, Yasuki Higashimura, Kazuki Okamoto, Fumihide Isohashi, Yoshihisa Nakano, and Hiroshi Inui.

Biochem. Biophys. Res. Commun. 雑誌 Elsevier   373 ( 3 )   373 - 377   2008.08

RanBP10 acts as a novel coactivator for the androgen receptor Reviewed

Naoki Harada, Tsuyoshi Yokoyama, Ryoichi Yamaji*, Yoshihisa Nakano, and Hiroshi Inui.

Biochem. Biophys. Res. Commun. 雑誌 Elsevier   368 ( 1 )   121 - 125   2008.03

Resveratrol down-regulates the androgen receptor at the post-translational level in prostate cancer cells Reviewed

Naoki Harada, Yohei Murata, Ryoichi Yamaji*, Takumi Miura, Hiroshi Inui, and Yoshihisa Nakano.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   53 ( 6 )   556 - 560   2007.12

Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells Reviewed

Naoki Harada, Ryoko Yasunaga, Yasuki Higashimura, Ryoichi Yamaji*, Katsumi Fujimoto, Joel Moss, Hiroshi Inui, and Yoshihisa Nakano.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   282 ( 31 )   22651 - 22661   2007.08

Glyceraldehyde-3-phosphate dehydrogenase in the extracellular space inhibits cell spreading. Reviewed

Ryoichi Yamaji*, Emi Chatani, Naoki Harada, Kenji Sugimoto, Hiroshi Inui, and Yoshihisa Nakano.

Biochim. Biophys. Acta (General Subjects) 雑誌 Elsevier   1726 ( 3 )   261 - 271   2005.11

Regulation of body heat production by nuclear receptors and its modulation by food factors

Grant-in-Aid for Scientific Research(B)  2024

ラカンカトリテルペノイドの生理機能と配糖体脱糖化酵素に関する研究

Grant-in-Aid for Scientific Research(C)  2024

Neuronal mechanism of hyperphagia in High fat foods

Grant-in-Aid for Scientific Research(B)  2024

低酸素下で形成される動的な代謝酵素集合体METAbody制御仮説の構築

Grant-in-Aid for Scientific Research(B)  2024

Laboratory : Chemistry of Biological Molecules

2021   Practical Training  

Topics in Nutrition Biochemistry and Functional Foods

2021    

General Principles of Applied Biological Chemistry

2021