森永賞

2012年06月   公益財団法人　森永奉仕会   胎児、新生児期におけるテストステロンサージの身体的発達における影響

Age-dependent sex difference of non-alcoholic fatty liver disease in TSOD and db/db mice 査読

Erdenetsogt Dungubat, Hiroyuki Kusano, Ichiro Mori, Hirosuke Tawara, Mitsuko Sutoh, Naoki Ohkura, Masakatsu Takanashi, Masahiko Kuroda, Naoki Harada, Emiko Udo, Masakazu Souda, Bungo Furusato, Toshio Fukusato, Yoshihisa Takahashi*.

PLoS ONE   17 ( 12 )   e0278580   2022年12月

Transport form and pathway from intestine to peripheral tissues and intestinal absorption and metabolism properties of oleamide 査読

Yasuyuki Kobayashi, Natsumi Watanabe, Reina Hiura, Mai Kubota, Kousuke Furuta, Keiichiro Sugimoto, Kaeko Murota, Eri Nakamura, Toshiki Matsuura, Kenji Kai, Takashi Inui, Tomoya Kitakaze, Naoki Harada, Ryoichi Yamaji*.

J. Agric. Food Chem.   70   15499 - 15508   2022年12月

Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice 査読

Naoki Harada*, Keitaro Kubo, Teruaki Onishi, Tomoya Kitakaze, Tsuyoshi Goto, Hiroshi Inui, Ryoichi Yamaji.

J. Biol. Chem.   298 ( 12 )   102619   2022年12月

Carotenoid transporter CD36 expression depends on hypoxia-inducible factor-1α in mouse soleus muscles 査読

Tomoya Kitakaze, Takashi Sugihira, Hiromichi Kameyama, Asami Maruchi, Yasuyuki Kobayashi, Naoki Harada, and Ryoichi Yamaji*.

J. Clin. Biochem. Nutr.   71 ( 2 )   112 - 131   2022年09月

Dietary oleamide attenuates obesity induced by housing mice in small cages 査読

Yasuyuki Kobayashi, Mai Kubota, Keiichiro Sugimoto, Tomoya Kitakaze, Naoki Harada, Ryoichi Yamaji*.

Biosci. Biotechnol. Biochem.   86 ( 8 )   1095 - 1105   2022年07月

Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid 査読 国際共著

Naoki Harada*, Yumi Arahori, Mai Okuyama, Paula B. Luis, Akil I. Joseph, Tomoya Kitakaze, Naoki Goshima, Claus Schneider, Hiroshi Inui, and Ryoichi Yamaji.

Biochem. Biophys. Res. Commun. 雑誌   595   41 - 46   2022年03月

Identification of G-protein coupled receptor 55 (GPR55) as a target of curcumin 査読 国際共著

Naoki Harada*, Mai Okuyama, Yoshiaki Teraoka, Yumi Arahori, Yoh Shinmori, Hiroko Horiuchi, Paula B. Luis, Akil I. Joseph, Tomoya Kitakaze, Shigenobu Matsumura, Tohru Hira, Norio Yamamoto, Takashi Iuni, Naoki Goshima, Claus Schneider, Hiroshi Inui, and Ryoichi Yamaji.

npj Sci. Food   6   4   2022年01月

Exopolysaccharides from a Scandinavian fermented milk viili increase butyric acid and Muribaculum members in the mouse gut 査読

Takuya Yamane*, Satoshi Handa, Momoko Imai, Naoki Harada, Tatsuji Sakamoto, Tetsuo Ishida, Takenori Nakagaki, Yoshihisa Nakano.

Food Chem. Mol. Sci. 雑誌   3   2021年12月

Oleamide rescues tibialis anterior muscle atrophy of mice housed in small cages 査読

Yasuyuki Kobayashi, Natsumi Watanabe, Tomoya Kitakaze, Takeshi Izawa, Keiichiro Sugimoto, Kenji Kai, Naoki Harada, and Ryoichi Yamaji*.

Br. J. Nutr. 雑誌   126 ( 4 )   481 - 491   2021年08月

Aronia juice supplementation inhibits lipid accumulation in both normal and obesity model mice 査読

Takuya Yamane*, Momoko Imai, Satoshi Handa, Naoki Harada, Ryoichi Yamaji, Tatsuji Sakamoto, Tetsuo Ishida, Hiroshi Inui, Takenori Nakagaki, and Yoshihisa Nakano.

PharmaNutrition 雑誌   14   2020年12月

Effects of caffeine and chlorogenic acid on nonalcoholic steatohepatitis in mice induced by choline-deficient, L-amino acid-defined, high-fat diet 査読

Erdenetsogt Dungubat, Shiori Watabe, Arisa Togashi-Kumagai, Masato Watanabe, Yasuyuki Kobayashi, Naoki Harada, Ryoichi Yamaji, Toshio Fukusato, Galtsog Lodon, Badamjav Sevjid, Yoshihisa Takahashi*.

Nutrients 雑誌   12   2020年12月

Relationship between gut environment, feces-to-food ratio, and androgen deficiency-induced metabolic disorders 査読

Naoki Harada*, Yukari Minami, Kazuki Hanada, Ryo Hanaoka, Yasuyuki Kobayashi, Takeshi Izawa, Takashi Sato, Shigeaki Kato, Hiroshi Inui, and Ryoichi Yamaji.

Gut Microbes 雑誌   12 ( 1 )   2020年11月

Effects of low ethanol consumption on nonalcoholic steatohepatitis in mice 査読

Yoshihisa Takahashi*, Shiori Watabe, Arisa Togashi-Kumagai, Masato Watanabe, Erdenetsogt Dungubat, Hiroyuki Kusano, Yasuyuki Kobayashi, Naoki Harada, Ryoichi Yamaji, Keiichiro Sugimoto, Toshio Fukusato.

Alcohol 雑誌   87   51 - 61   2020年09月

Biological activity of pseudovitamin B12 on cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase in mammalian cultured COS-7 cells 査読

Tomohiro Bito*, Mariko Bito, Tomomi Hirooka, Naho Okamoto, Naoki Harada, Ryoichi Yamaji, Yoshihisa Nakano, Hiroshi Inui, and Fumio Watanabe.

Molecules 雑誌   25   2020年07月

β-Cryptoxanthin improves p62 accumulation and muscle atrophy in the soleus muscle of senescence-accelerated mouse-prone 1 mice 査読

Mari Noguchi, Tomoya Kitakaze, Yasuyuki Kobayashi, Katsuyuki Mukai, Naoki Harada, and Ryoichi Yamaji*.

Nutrients 雑誌   12   2020年07月

Food texture affects glucose tolerance by altering pancreatic β-cell function in mice consuming high-fructose corn syrup 査読

Naoki Harada*, Masayuki Nomura, Yasuhiro Yoda, Shigenobu Matsumura, Hiroshi Inui, and Ryoichi Yamaji.

PLoS One 雑誌   15 ( 5 )   2020年05月

Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice 査読

Naoki Harada*, Kazuki Hanada, Yukari Minami, Tomoya Kitakaze, Yoshiyuki Ogata, Hayato Tokumoto, Takashi Sato, Shigeaki Kato, Hiroshi Inui, and Ryoichi Yamaji.

Am. J. Physiol. Endocrinol. Metab. 雑誌   318   E525 - E537   2020年04月

Extracellular transglutaminase 2 induces myotube hypertrophy through G protein-coupled receptor 56 査読

Tomoya Kitakaze, Miki Yoshikawa, Yasuyuki Kobayashi, Naohiro Kimura, Naoki Goshima, Takahiro Ishikawa, Yoshiyuki Ogata, Yoko Yamashita, Hitoshi Ashida, Naoki Harada, and Ryoichi*

Biochim. Biophys. Acta – Mol. Cell Res. 雑誌   1867   2020年02月

Effects of crystalline and amorphous forms of paramylon from Euglena gracilis on the development of water-immersion restraint stress-induced gastric ulcer 査読

Misa Ogushi*, Momoko Imai, Minako Yoshizawa, Kengo Suzuki, and Naoki Harada.

Food Sci. Technol. Res. 雑誌   26 ( 1 )   153 - 158   2020年01月

Tomatidine, a steroidal alkaloid from green tomatoes, reduces palmitate-induced lipid accumulation by activating AMPK via vitamin D receptor-mediated signaling in human HepG2 hepatocytes 査読

Hikari Kusu, Hiroki Yoshida, Michiko Kudo, Mai Okuyama, Naoki Harada, Kentaro Tsuji-Naito, and Mitsugu Akagawa*.

Mol. Nutr. Food Res.   63 ( 22 )   2019年12月

Fetal androgen signaling defects affect pancreatic β-cell mass and function, leading to glucose intolerance in high-fat diet-fed male rats 査読

Naoki Harada*, Yusuke Yotsumoto, Takahiro Katsuki, Yasuhiro Yoda, Tatsuya Masuda, Masayuki Nomura, Nobuaki Shiraki, Hiroshi Inui, and Ryoichi Yamaji.

Am. J. Physiol. Endocrinol. Metab. 雑誌   317   E731 - E741   2019年11月

5-Hydroxy-7-methoxyflavone derivatives from Kaempferia parviflora induce skeletal muscle hypertrophy 査読

Shintaro Ono, Naoki Yoshida, Daisuke Maekawa, Tomoya Kitakaze, Yasuyuki Kobayashi, Takehiro Kitano, Takanori Fujita, Hirotaka Okuwa-Hayashi, Naoki Harada, Yoshihisa Nakano, and Ryoichi Yamaji*.

Food Sci. Nutr. 雑誌   7   312 - 321   2019年01月

Role of androgens in energy metabolism affecting on body composition, metabolic syndrome, type 2 diabetes, cardiovascular disease, and longevity: Lessons from a meta-analysis and rodent studies.

Naoki Harada*.

Biosci. Biotechnol. Biochem. 雑誌 Taylor Francis   82 ( 10 )   1667 - 1682   2018年10月

Lactoferrin promotes murine C2C12 myoblast proliferation and differentiation, and myotube hypertrophy

Tomoya Kitakaze, Meiku Oshimo, Yasuyuki Kobayashi, Mizuyuki Ryu, Yasushi A. Suzuki, Hiroshi Inui, Naoki Harada, and Ryoichi Yamaji*.

Mol. Med. Rep. 雑誌   17   5912 - 5920   2018年04月

Androgen signaling expands β-cell mass in male rats and β-cell androgen receptor is degraded under high-glucose conditions 査読

Naoki Harada*, Yasuhiro Yoda, Yusuke Yotsumoto, Tatsuya Masuda, Yuji Takahashi, Takahiro Katsuki, Kenji Kai, Nobuaki Shiraki, Hiroshi Inui, and Ryoichi Yamaji.

Am. J. Physiol. Endocrinol. Metab. 雑誌   314   E274 - E286   2018年03月

Theophylline suppresses interleukin-6 expression by inhibiting glucocorticoid receptor signaling in pre-adipocytes. 査読

Takakazu Mitani, Tomohide Takaya, Naoki Harada, Shigeru Katayama*, Ryoichi Yamaji, Soichiro Nakamura, Hitoshi Ashida.

Arch. Biochem. Biophys. 雑誌 Elsevier   646   98 - 106   2018年03月

Stereoselective effects of lactate enantiomers on the enhancement of 3T3-L1 adipocyte differentiation 査読

Naoki Harada*, Ito Hirano, Hiroshi Inui, and Ryoichi Yamaji.

Biochem. Biophys. Res. Commun. 雑誌   498   105 - 110   2018年03月

Lactoferrin induces tropoelastin expression by activating the lipoprotein receptor-related protein 1-mediated phosphatidylinositol 3-kinase/Akt pathway in human dermal fibroblasts 査読

Mizuyuki Ryu, Asuka Nogami, Tomoya Kitakaze, Naoki Harada, Yasushi A Suzuki, and Ryoichi Yamaji*.

Cell Biol. Int. 雑誌   41   1325 - 1334   2017年12月

S-Equol activates cAMP signaling at the plasma membrane of INS-1 pancreatic β-cells and protects against streptozotocin-induced hyperglycemia by increasing β-cell function in male mice

Hiroko Horiuchi, Atsuko Usami, Rie Shirai, Naoki Harada*, Shinichi Ikushiro, Toshiyuki Sakaki, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji.

J. Nutr. 雑誌   147 ( 9 )   1631 - 1639   2017年09月

Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor β and increases skeletal muscle mass in young female mice 査読

Masahiro Ogawa, Takehiro Kitano, Natsuha Kawata, Takashi Sugihira, Tomoya Kitakaze, Naoki Harada and Ryoichi Yamaji*.

J. Nutr. Biochem. 雑誌   49 ( 9 )   1631 - 1639   2017年08月

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) aggregation causes mitochondrial dysfunction during oxidative stress-induced cell death

Masanori Itakura, Hidemitsu Nakajima*, Takeya Kubo, Akihiro Kaneshige, Naoki Harada, Takeshi Izawa, Yasu-Taka Azuma, Mitsuru Kuwamura, Ryoichi Yamaji, and Tadayoshi Takeuchi.

J. Biol. Chem. 著書   292 ( 11 )   4727 - 4742   2017年03月

Hypogonadism alters cecal and fecal microbiota in male mice 査読

Naoki Harada*, Ryo Hanaoka, Kazuki Hanada, Takeshi Izawa, Hiroshi Inui, and Ryoichi Yamaji.

Gut Microbes 雑誌   7 ( 6 )   533 - 539   2016年11月

Mogrol Derived from Siraitia grosvenorii Mogrosides Suppresses 3T3-L1 Adipocyte Differentiation by Reducing cAMP-Response Element-Binding Protein Phosphorylation and Increasing AMP-Activated Protein Kinase Phosphorylation 査読

Naoki Harada*, Mikako Ishihara, Hiroko Horiuchi, Yuta Ito, Hiromitsu Tabata, Yasushi A Suzuki, Yoshihisa Nakano, Ryoichi Yamaji, and Hiroshi Inui*.

PLoS ONE 雑誌   11 ( 9 )   2016年09月

The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy 査読

Tomoya Kitakaze, Tomotaka Sakamoto, Takehiro Kitano, Naoki Inoue, Fumihito Sugihara, Naoki Harada, and Ryoichi Yamaji*.

Biochem. Biophys. Res. Commun. 雑誌   478 ( 3 )   2690 - 2699   2016年09月

pVHL-mediated degradation of HIF-2αregulates estrogen receptor α expression in normoxic breast cancer cells 査読

Yasuki Higashimura, Tomoya Kitakaze, Naoki Harada, Hiroshi Inui, Yoshihisa Nakano, Ryoichi Yamaji*.

FEBS Lett. 雑誌 Wiley   590 ( 16 )   2690 - 2699   2016年08月

Castration influences intestinal microflora and induces abdominal obesity in high-fat diet-fed mice 査読

Naoki Harada*, Ryo Hanaoka, Hiroko Horiuchi, Tomoya Kitakaze, Takakazu Mitani, Hiroshi Inui, and Ryoichi Yamaji.

Sci. Rep. 雑誌 Nature publication group   6   2016年03月

β-Carotene increases muscle mass and hypertrophy in the soleus muscle in mice 査読

Tomoya Kitakaze, Naoki Harada, Hidetaka Imagita, Ryoichi Yamaji*

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   61 ( 6 )   481 - 487   2015年12月

Glyceraldehyde-3-phosphate dehydrogenase aggregates accelerate amyloid-βamyloidogenesis in Alzheimer disease 査読

Masanori Itakura, Hidemitsu Nakajima*, Takeya Kubo, Yuko Semi, Satoshi Kume, Shusaku Higashida, Akihiro Kaneshige, Mitsuru Kuwamura, Naoki Harada, Yasu-Taka Azuma, Ryoichi Yamaji, Takashi Inui, and Tadayoshi Takeuchi.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   290 ( 43 )   26072 - 26087   2015年10月

Protein arginine metyltransferase 10 is required for androgen-dependent proliferation of LNCaP prostate cancer cells 査読

Naoki Harada*, Toshiki Takagi, Yoshihisa Nakano, Ryoichi Yamaji, and Hiroshi Inui.

Biosci. Biotechnol. Biochem. 雑誌 Taylor Francis   79 ( 9 )   1430 - 1437   2015年09月

Autophagic degradation of the androgen receptor mediated by increased phosphorylation of p62 suppresses apoptosis in hypoxia 査読

Takakazu Mitani, Masato Minami, Naoki Harada, Hitoshi Ashida, and Ryoichi Yamaji*.

Cell. Signal. 雑誌   27   1994 - 2001   2015年07月

Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic β-cells 査読

Naoki Harada*, Takahiro Katsuki, Yuji Takahashi, Tatsuya Masuda, Mariko Yoshinaga, Tetsuya Adachi, Takeshi Izawa, Mitsuru Kuwamura, Yoshihisa Nakano, Ryoichi Yamaji, and Hiroshi, Inui.

J. Cell. Biochem. 雑誌 Wiley   116 ( 6 )   998 - 1006   2015年06月

Female-specific regulation of skeletal muscle mass by USP19 in young mice 査読

Masahiro Ogawa, Tomoya Kitakaze, Naoki Harada, and Ryoichi Yamaji*.

J. Endocrinol. 雑誌 Society for Endocrinology   225 ( 3 )   135 - 145   2015年06月

Competitive and compensatory effects of androgen signaling and glucocorticoid signaling 査読

Naoki Harada*, Hiroshi Inui, and Ryoichi Yamaji.

Receptors Clin. Invest. 雑誌 Smart Science Technology   2 ( 3 )   2015年05月

Inhibitory effects of Eucalyptus and Banaba leaf extracts on nonalcoholic steatohepatitis induced by a high-fructose/high-glucose diet in rats 査読

Yoshihisa Takahashi*, Keiichiro Sugimoto, Yurie Soejima, Arisa Kumagai, Tatsuki Koeda, Aiko Shojo, Kazuya Nakagawa, Naoki Harada, Ryoichi Yamaji, Hiroshi Inui, Toshikazu Yamanouchi, and Toshio Fukusato.

Biomed. Res. Int. 雑誌 Hindawi   2015   2015年04月

Resveratrol inhibits hypoxia-inducible factor-1α-mediated androgen receptor signaling and represses tumor progression in castration-resistant prostate cancer 査読

Takakazu Mitani, Naoki Harada, Shinji Tanimori, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji*.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   60 ( 4 )   276 - 282   2014年10月

S-Equol enantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells 査読

Hiroko Horiuchi, Naoki Harada*, Tetsuya Adachi, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   60 ( 4 )   291 - 296   2014年10月

Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells 査読

Takakazu Mitani, Yuta Ito, Naoki Harada, Yoshihisa Nakano, Hiroshi Inui, Hitoshi Ashida, and Ryoichi Yamaji*

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   60 ( 2 )   122 - 128   2014年06月

Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4´-amino-3,5-dihydroxy-trans-stilbene 査読

Yuta Ito, Takakazu Mitani, Naoki Harada, Atsushi Isayama, Shingi Tanimori, Shigeo Takenaka, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji*.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   59 ( 4 )   358 - 364   2013年09月

Biochemical characterization of a GH53 endo-beta-1,4-galactanase and a GH35 exo-beta-1,4-galactanase from Penicillium chrysogenum 査読

Tatsuji Sakamoto*, Yuichi Nishimura, Yosuke Makino, Yoichi Sunagawa, and Naoki Harada.

Appl. Microbiol. Biotechnol. 雑誌 Supringer   97 ( 7 )   2895 - 2906   2013年04月

The preventive effect of beta-carotene on denervation-induced soleus muscle atrophy in mice 査読

Masahiro Ogawa, Yoshihiro Kariya, Tomoya Kitakaze, Ryoichi Yamaji*, Naoki Harada, Tatsuji Sakamoto, Keisuke Hosotani, Yoshihisa Nakano, and Hiroshi Inui.

Brit. J. Nutr. 雑誌 Cambridge University Press   109   1349 - 1358   2013年04月

Coordinated action of hypoxia-inducible factor-1alpa and beta-catenin in androgen receptor signaling 査読

Takakazu Mitani, Naoki Harada, Yoshihisa Nakano, Hiroshi Inui, and Ryoichi Yamaji*.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   287 ( 40 )   33594 - 33606   2012年09月

Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostae cancer LNCaP cells 査読

Naoki Harada*, Kaoru Inoue, Ryoichi Yamaji, Yoshihisa Nakano, and Hiroshi Inui.

Cancer Sci. 雑誌 Wiley   103 ( 6 )   1022 - 1027   2012年06月

Purification, characterization and gene cloning of two forms of a thermostable endo-xylanase from Streptomyces sp. SWU10 査読

Warin Deesukon, Yuichi Nishimura, Naoki Harada, Tatsuji Sakamoto*, and Wasana Sukhumsirichart*.

Process Biochem. 雑誌 Elsevier   46   2255 - 2262   2011年12月

Estrogens repress differentiation of skeletal muscle by increasing ubiquitin-specific peptidase 19 through estrogen receptor alpha 査読

Masahiro Ogawa, Ryoichi Yamaji*, Yasuki Higashimura, Naoki Harada, Hitoshi Ashida, Yoshihisa Nakano, and Hiroshi Inui.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   286 ( 48 )   41455 - 41465   2011年12月

Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2a through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms 査読

Yasuki Higashimura, Takashi Terai, Ryoichi Yamaji*, Takakazu Mitani, Masahiro Ogawa, Naoki Harada, Hiroshi Inui, and Yoshihisa Nakano.

Biochem. Biophys. Res. Commun. 雑誌 Elsevier   413 ( 2 )   201 - 205   2011年09月

Suppression of inducible ntric oxide synthase expression and amelioration of lipopolysaccharide-induced liver injury by polyphenolic compounds in eucalyptus globulus leaf extract 査読

Keiichiro Sugimoto, Sayaka Sakamoto, Kazuya Nakagawa, Shuichi Hayashi, Naoki Harada, Ryoichi Yamaji, Yoshihisa Nakano, and Hiroshi Inui*.

Food Chem. 雑誌 Elsevier   125   442 - 446   2011年03月

Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells 査読

Yasuki Higashimura, Yoshito Nakajima, Ryoichi Yamaji*, Naoki Harada, Futoshi Shibasaki, Yoshihisa Nakano, and Hiroshi Inui.

Arch. Biochem. Biophys. 雑誌 Elsevier   509   2011年02月

Hypoxia enhances transcriptional activity of androgen receptor through hypoxia-inducible factor-1alpha in a low androgen environment 査読

Takakazu Mitani, Ryoichi Yamaji*, Yasuki Higashimura, Naoki Harada, Yoshihisa Nakano, and Hiroshi Inui.

J. Steroid Biochem. Mol. Biol. 雑誌 Elsevier   123 ( 41641 )   58 - 64   2011年01月

Inhibitory mechanisms of the transcriptional activity of androgen receptor by resveratrol: implication of DNA-binding and acetylation of the receptor 査読

Naoki Harada, Kiyotaka Atarashi, Yohei Murata, Ryoichi Yamaji*, Yoshihisa Nakano, and Hiroshi Inui.

J. Steroid Biochem. Mol. Biol. 雑誌 Elsevier   123 ( 41641 )   65 - 70   2011年01月

Construction of a dominant negative form of human hypoxia-inducible factor-2alpha 査読

Yasuki Higashimura, Ryoichi Yamaji*, Naoki Harada, Motoyuki Nakao, Yoshihisa Nakano, and Hiroshi Inui.

Biosci. Biotechnol. Biochem. 雑誌 Japan Society for Bioscience, Biotechnology and Agrochemistry   74 ( 10 )   2100 - 2102   2010年10月

Involvement of three glutamine tracts in human androgen receptor transactivation 査読

Naoki Harada, Takakazu Mitani, Yasuki Higashimura, Ryoichi Yamaji*, Kazuki Okamoto, Yoshihisa Nakano, and Hiroshi Inui.

J. Steroid Biochem. Mol. Biol. 雑誌 Elsevier   118 ( 41641 )   77 - 84   2010年09月

A yeast bioassay for androgenic and anti-androgenic compounds based on the NH2- and COOH-terminal interaction of androen receptor 査読

Masahiro Ogawa, Ryoichi Yamaji*, Takakazu Mitani, Yohei Murata, Motoyuki Nakao, Naoki Harada, Yoshihisa Nakano, and Hiroshi Inui.

Biosci. Biotechnol. Biochem. 雑誌 Japan Society for Bioscience, Biotechnology and Agrochemistry   74 ( 9 )   1965 - 1968   2010年09月

Potential use of bischofia javanica as an active ingredient of functional foods and cosmeceutical products possessing hyaluronidase, collagenase, tyrosinase and urease inhibitory effects 査読

Florin Barla, Asako Horinishi, Naoki Harada, Ryoichi Yamaji, Toshiki Enomoto*, Nobutaka Suzuki, Hisayuki Maenaka, Yoshihisa Nakano, and Hiroshi Inui.

Jpn. J. Compl. Alternative Med. 雑誌 The Japanese Society for Complementary and Alternative Medicine   7 ( 2 )   129 - 133   2010年

Inhibitive effects of alkyl gallates on hyaluronidase and collagenase 査読

Florin Barla, Hayato Higashijima, Shingo Funai, Keiichiro Sugimoto, Naoki Harada, Ryoichi Yamaji, Tomoyuki Fujita, Yoshihisa Nakano, and Hiroshi Inui*.

Biosci. Biotechnol. Biochem. 雑誌 Japan Society for Bioscience, Biotechnology and Agrochemistry   73 ( 10 )   2335 - 2337   2009年10月

Cobalamin deficiency results in an abnornal increase in L-methylmalonyl-CoA mutase expresseion in rat liver and COS-7 cells. 査読

Motoyuki Nakao, Shoko Hironaka, Naoki Harada, Tetsuya Adachi, Tomohiro Bito, Yukinori Yauta, Fumio Watanabe, Takumi Miura, Ryoichi Yamaji, Hiroshi Inui*, and Yoshihisa Nakano.

Br. J. Nutr. 雑誌 Cambridge University Press   101   484 - 490   2009年09月

ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor 査読

Naoki Harada, Yuji Ohmori, Ryoichi Yamaji*, Yasuki Higashimura, Kazuki Okamoto, Fumihide Isohashi, Yoshihisa Nakano, and Hiroshi Inui.

Biochem. Biophys. Res. Commun. 雑誌 Elsevier   373 ( 3 )   373 - 377   2008年08月

RanBP10 acts as a novel coactivator for the androgen receptor 査読

Naoki Harada, Tsuyoshi Yokoyama, Ryoichi Yamaji*, Yoshihisa Nakano, and Hiroshi Inui.

Biochem. Biophys. Res. Commun. 雑誌 Elsevier   368 ( 1 )   121 - 125   2008年03月

Resveratrol down-regulates the androgen receptor at the post-translational level in prostate cancer cells 査読

Naoki Harada, Yohei Murata, Ryoichi Yamaji*, Takumi Miura, Hiroshi Inui, and Yoshihisa Nakano.

J. Nutr. Sci. Vitaminol. 雑誌 The Vitamin Society of Japan, Japanese Society for Nutrition and Food Science   53 ( 6 )   556 - 560   2007年12月

Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cells 査読

Naoki Harada, Ryoko Yasunaga, Yasuki Higashimura, Ryoichi Yamaji*, Katsumi Fujimoto, Joel Moss, Hiroshi Inui, and Yoshihisa Nakano.

J. Biol. Chem. 雑誌 The American Society for Biochemistry and Molecular Biology   282 ( 31 )   22651 - 22661   2007年08月

Glyceraldehyde-3-phosphate dehydrogenase in the extracellular space inhibits cell spreading. 査読

Ryoichi Yamaji*, Emi Chatani, Naoki Harada, Kenji Sugimoto, Hiroshi Inui, and Yoshihisa Nakano.

Biochim. Biophys. Acta (General Subjects) 雑誌 Elsevier   1726 ( 3 )   261 - 271   2005年11月

運動によるビタミンA代謝酵素の発現変動と筋肥大の関係について 国内会議

中辻あいの、北風智也、原田直樹、山地亮一

第63回 日本栄養・食糧学会 近畿支部大会  2024年10月 

去勢による男性ホルモン低下とフルクトース摂取による腸内細菌叢－内臓脂肪量－脂肪肝への影響 国内会議

髙橋央樹、速水陽平、原田直樹、Erdenetsogt Dungubat、中澤昌美、北風智也、杉本圭一郎、乾博、高橋芳久、山地亮一

日本農芸化学会関西支部第531回講演会  2024年07月 

骨格筋におけるレチノイン酸受容体γの機能 国内会議

大場智貴、岡野結衣、北風智也、原田直樹、山地亮一.

日本ビタミン学会第76回大会   2024年05月 

Inhibitory effects of putrescine on metabolic dysfunction-associated steatepatitis in mice 国際会議

Erdenetsogt Dungubat, Yuhko Yamada, Shinichiro Ohno, Tomohiro Umezu, Bin Shen, Akira Saitoh, Hajime Horiuchi, Masahiko Kuroda, Hirosuke Tawara, Mitsuko Sutoh, Naoki Ohkura, Hiroki Takahashi, Naoki Harada, Ryoichi Yamaji, Hiroyuki Kusano, Emiko Udo, Masakazu Souda, Bungo Furusato, Toshio Fukusato, Yoshihisa Takahashi

APASL (the Asian Pacific Association for the Study of the Liver) Oncology 2024 

代謝機能障害関連脂肪肝炎モデルマウスに対するプトレシンの抑制効果 国内会議

森グレイスリン真理愛、俵博祐、大藏直樹、髙橋央樹、原田直樹、山地亮一、有働恵美子、古里文吾、黒田雅彦、高橋芳久

第114回 日本病理学会総会 

核内受容体を介した体熱産生制御機構の解明と食品成分による調節

基盤研究(B)  2024年

ラカンカトリテルペノイドの生理機能と配糖体脱糖化酵素に関する研究

基盤研究(C)  2024年

油脂を食べ過ぎてしまう神経機構の解明

基盤研究(B)  2024年

低酸素下で形成される動的な代謝酵素集合体METAbody制御仮説の構築

基盤研究(B)  2024年

油脂を食べ過ぎてしまう神経機構の解明

基盤研究(B)  2023年

低酸素下で形成される動的な代謝酵素集合体METAbody制御仮説の構築

基盤研究(B)  2023年

核内受容体を介した体熱産生制御機構の解明と食品成分による調節

基盤研究(B)  2023年

組織によって生理的濃度域が異なるインスリンの感知機構とその役割

挑戦的研究(開拓・萌芽)  2022年

核内受容体を介した体熱産生制御機構の解明と食品成分による調節

基盤研究(B)  2022年

低酸素下で形成される動的な代謝酵素集合体METAbody制御仮説の構築

基盤研究(B)  2022年

食品代謝栄養学特論

2024年度   週間授業   大学院

生体成分実験

2024年度   週間授業   大学

基礎化学実験

2024年度   週間授業   大学院

代謝生化学

2021年度    

生命環境科学入門

2021年度    

初年次ゼミナール【どのように齢を重ねるかを考える】

2021年度    

生体成分実験

2021年度   実習  

食品代謝栄養学特論

2021年度    

生命機能化学概論

2021年度