In vivo transfection of cytokine genes into tumor cells using a synthetic vehicle promotes antitumor immune responses in a visceral tumor model Reviewed

Watanabe S, Takagi A, Yuba E, Kojima C, Dei N, Matsumoto A, Tanikawa J, Kawamura T, De Silva NH, Izawa T, Akazawa T, Kanegi R, Hatoya S, Inaba T, Sugiura K.

FASEB Journal   37 ( 11 )   e23228   2023.11（ ISSN:08926638 ）

Pleural mesothelioma in a California sea lion (Zalophus californianus) Reviewed

Takami Y, Tanaka M, Morita M, Maruno T, Anai N, Sudo T, Kezuka C, Izawa T, Yamate J, Kuwamura M.

The Journal of veterinary medical science   85 ( 9 )   1030 - 1033   2023.09

Disrupted neurogenesis, gliogenesis, and ependymogenesis in the Ccdc85c knockout rat for hydrocephalus model Reviewed

Hasan MM, Konishi S, Tanaka M, Izawa T, Yamate J, Kuwamura M.

Cells and Development   175   203858   2023.09（ ISSN:26672901 ）

The effect of lipopolysaccharide on liver homeostasis and diseases based on the mutual interaction of macrophages, autophagy, and damage-associated molecular patterns in male F344/DuCrlCrlj rats Reviewed

Takami Y, Tanaka M, Izawa T, Kuwamura M, Yamate J.

Veterinary Pathology   60 ( 4 )   461 - 472   2023.07（ ISSN:03009858 ）

L-arginine-induced pancreatitis aggravated by inhibiting Na⁺/Ca²⁺ exchanger 1 Reviewed

Ono N, Horikoshi J, Izawa T, Nishiyama K, Tanaka M, Kuwamura M, Azuma Y-T.

Journal of Veterinary Medical Science   85 ( 6 )   657 - 666   2023.07（ ISSN:09167250 ）

Interleukin-19 Gene-Deficient Mice Promote Liver Fibrosis via Enhanced TGF-β Signaling, and the Interleukin-19-CCL2 Axis Is Important in the Direction of Liver Fibrosis Reviewed

Ono N, Fujita T, Miki M, Nishiyama K, Izawa T, Aoyama T, Kuwamura M, Fujii H, Azuma YT.

Biomedicines   11 ( 7 )   2064   2023.07

Clinical findings using echocardiography and plasma cardiac troponin I and pathological findings in dogs with hypertrophic cardiomyopathy: A retrospective study Reviewed

Ando T, Izawa T, Nishida H, Akiyoshi H.

Open Veterinary Journal   13 ( 6 )   742 - 752   2023.07（ ISSN:22264485 ）

Contrast-enhanced computed tomography and cross-sectional anatomy of the trunk in the brownbanded bamboo shark (Chiloscyllium punctatum) Reviewed

Ito T, Tanaka T, Kiyatake I, Izawa T, Furuya M, Sasai K.

Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia   52 ( 3 )   437 - 447   2023.05（ ISSN:03402096 ）

Contrast-enhanced computed tomography and cross-sectional anatomy of the trunk in the brownbanded bamboo shark (Chiloscyllium punctatum) Reviewed

Ito T, Tanaka T, Kiyatake I, Izawa T, Furuya M, Sasai K.

Anatomia, Histologia, Embryologia   52 ( 3 )   437 - 447   2023.05

Macrophage pathology in hepatotoxicity Reviewed

Yamate J, Izawa T, Kuwamura M.

Journal of Toxicologic Pathology   36 ( 2 )   51 - 68   2023.04（ ISSN:09149198 ）

Absence of Increased Susceptibility to Acetaminophen-Induced Liver Injury in a Diet-Induced NAFLD Mouse Model Reviewed International coauthorship

Izawa T, Travlos GS, Cortes RA, Clayton NP, Sills RC, Pandiri AR.

Toxicologic Pathology   51 ( 3 )   112 - 125   2023.04（ ISSN:01926233 ）

Atypical hypoadrenocorticism with intact zona glomerulosa of the adrenal cortex after long-term observation: a case report of a dog Reviewed

Hatoya S, Kanegi R, Nabetani T, Oji S, Izawa T, Hirai S, Sugiura K.

Journal of Veterinary Medical Science   85 ( 1 )   9 - 13   2023.01（ ISSN:09167250 ）

Analyses of damage-associated molecular patterns, particularly biglycan, in cisplatin-induced rat progressive renal fibrosis Reviewed

Nakagawa M, Izawa T, Kuwamura M, Yamate J.

Journal of Toxicologic Pathology   36 ( 3 )   181 - 185   2023（ ISSN:09149198 ）

Dietary iron overload enhances Western diet induced hepatic inflammation and alters lipid metabolism in rats sharing similarity with human DIOS Reviewed

Fujiwara S, Izawa T, Mori M, Atarashi M, Yamate J, Kuwamura M.

Scientific Reports   12 ( 1 )   21414   2022.12

The K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumors Reviewed

Sakamoto K, Lin B, Nunomura K, Izawa T, Nakagawa S.

Scientific Reports   12 ( 1 )   8121   2022.12

Expression of CCDC85C, a causative protein for hydrocephalus, and intermediate filament proteins during lateral ventricle development in rats Reviewed

Hasan MM, Konishi S, Tanaka M, Izawa T, Yamate J, Kuwamura M.

Experimental Animals   2022

Possible cytoprotection of low dose lipopolysaccharide in rat thioacetamide-induced liver lesions, focusing on the analyses of hepatic macrophages and autophagy Reviewed

Pervin M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

Toxicologic Pathology   2022

IL-19 contributes to the development of nonalcoholic steatohepatitis by altering lipid metabolism Reviewed

Azuma YT, Fujita T, Izawa T, Hirota K, Nishiyama K, Ikegami A, Aoyama T, Ike M, Ushikai Y, Kuwamura M, Fujii H, Tsuneyama K.

Cells   10 ( 12 )   2021.12

Systemic anaplastic large T-cell lymphoma with initial presentation of dysuria in a dog Reviewed

Kaneguchi A, Izawa T, Tanaka M, Suzuki H, Tani H, Kuwamura M, Yamate J

Journal of Comparative Pathology   189   26 - 30   2021.11

Properties of macrophages and lymphocytes appearing in rat renal fibrosis followed by repeated injection of cisplatin Reviewed

Matsuyama S, Pervin M, Nakagawa M, Izawa T, Kuwamura M, Yamate J.

The Journal of veterinary medical science   83 ( 9 )   1435 - 1442   2021.09

Oleamide rescues tibialis anterior muscle atrophy of mice housed in small cages Reviewed

Kobayashi Y, Watanabe N, Kitakaze T, Sugimoto K, Izawa T, Kai K, Harada N, Yamaji R.

British Journal of Nutrition   126 ( 4 )   481 - 491   2021.08（ ISSN:00071145 ）

Appearance of heterogeneous macrophages during development of isoproterenol-induced rat myocardial fibrosis Reviewed

Koga M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

Toxicologic Pathology   49 ( 5 )   2021.07

Involvement of neutrophils in rat livers by low-dose thioacetamide administration Reviewed

Kuramochi M, Izawa T, Kuwamura M, Yamate J.

The Journal of veterinary medical science   83 ( 3 )   390 - 396   2021.03

PHF24 is expressed in the inhibitory interneurons in rats Reviewed

Numakura Y, Uemura R, Tanaka M, Izawa T, Yamate J, Kuramoto T, Kaneko T, Mashimo T, Yamamoto T, Serikawa T, Kuwamura M.

Experimental Animals   70 ( 1 )   137 - 143   2021.02

Analyses of hemorrhagic diathesis in high-iron diet-fed rats Reviewed

Inai Y, Izawa T, Mori M, Atarashi M, Tsuchiya S, Kuwamura M, Yamate J.

Journal of Toxicologic Pathology   34 ( 1 )   33 - 41   2021.02

Immunophenotypical characterization of M1/M2 macrophages and lymphocytes in cisplatin-induced rat progressive renal fibrosis Reviewed

Nakagawa M, Karim MR, Izawa T, Kuwamura M, Yamate J.

Cells   10 ( 2 )   2021.01

Characterization of immature myofibroblasts of stellate cell or mesenchymal cell origin in D-galactosamine-induced liver injury in rats Reviewed

Rahman N, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

Veterinary Pathology   58 ( 1 )   80 - 90   2021.01

Parengyodontium album isolated from cutaneous lesions of a pacific white-sided dolphin (Lagenorhynchus obliquidens) during treatment for Paracoccidioidomycosis Ceti Reviewed

Kanegae H, Tomino N, Nakamura Y, Minakawa T, Yaguchi T, Izawa T, Sano A, Ueda K.

Mycopathologia   185 ( 6 )   1021 - 1031   2020.12

Seroprevalence of Antibodies Against Paracoccidioides Spp. in Captive Dolphins from Three Aquaria in Japan Reviewed

Minakawa T, Shumoto G, Kezuka C, Izawa T, Sasaki K, Yamaguchi S, Kamezaki N, Yamate J, Konno T, Sano A, Itano EN, Wada S, Willson C, Ueda K.

Mycopathologia   185 ( 6 )   1013 - 1020   2020.12

Relationship between gut environment, feces-to-food ratio, and androgen deficiency- induced metabolic disorders Reviewed

Harada N, Minami Y, Hanada K, Hanaoka R, Kobayashi Y, Izawa T, Sato T, Kato S, Inui H, Yamaji R.

Gut Microbes   12 ( 1 )   2020.11

Acetaminophen-induced rat hepatotoxicity based on m1/m2-macrophage polarization, in possible relation to damage-associated molecular patterns and autophagy Reviewed

Tsuji Y, Kuramochi M, Golbar HM, Izawa T, Kuwamura M, Yamate J.

International journal of molecular sciences   21 ( 23 )   2020.11

Effects of dexamethasone on hepatic macrophages in normal livers and thioacetamide-induced acute liver lesions in rats Reviewed

Hada N, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

Journal of Toxicologic Pathology   33 ( 4 )   237 - 246   2020.10

Dietary iron overload differentially modulates chemically-induced liver injury in rats Reviewed

Mori M, Izawa T, Inai Y, Aikawa R, Fujiwara S, Kuwamura M, Yamate J.

Nutrients   12 ( 9 )   2020.09

Participation of Somatic Stem Cells, Recognized by a Unique A3 Antibody, in Mucosal Epithelial Regeneration in Dextran Sulfate Sodium (DSS)–Induced Rat Colonic Lesions Reviewed

Nishina H, Katou-Ichikawa C, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

Toxicologic Pathology   48 ( 4 )   560 - 569   2020.06（ ISSN:01926233 ）

Participation of somatic stem cells, recognized by a unique A3 antibody, in mucosal epithelial regeneration in dextran sulfate sodium (DSS)-induced rat colonic lesions Reviewed

Nishina H, Kato-Ichikawa C, Kuramochi, M, Izawa T, Kuwamura M, Yamate J.

Toxicologic Pathology   48 ( 4 )   560 - 569   2020.06

Hepatocellular necrosis with prominent regenerative reactions in a zonisamide administrated dog. Reviewed

Takami Y, Izawa T, Tanaka M, Hatoya S, Nabetani T, Yamate J, Kuwamura M.

The Journal of veterinary medical science   82 ( 6 )   704 - 706   2020.06

An aortic body carcinoma with sarcomatoid morphology and chondroid metaplasia in a French Bulldog Reviewed

Morita C, Tanaka M, Noguchi S, Shimamura S, Wada Y, Izawa T, Yamate J, Kuwamura M.

The Journal of veterinary medical science   82 ( 5 )   576 - 579   2020.05

Participation of somatic stem cells, labeled by a unique antibody (A3) recognizing both n-glycan and peptide, to hair follicle cycle and cutaneous wound healing in rats Reviewed

Katou-Ichikawa C, Nishina H, Tanaka M, Takenaka S, Izawa T, Kuwamura M, Yamate J.

International journal of molecular sciences   21 ( 11 )   2020.05

Characterization of macrophages and myofibroblasts appearing in dibutyltin dichloride-induced rat pancreatic fibrosis Reviewed

Hashimoto A, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J

Toxicologic Pathology 雑誌   48 ( 3 )   509 - 523   2020.04

Carboxyl-, sulfonyl-, and phosphate-terminal dendrimers as a nanoplatform with lymph node targeting Reviewed

Nishimoto Y, Nagashima S, Nakajima K, Ohira T, Sato T, Izawa T, Yamate J, Higashikawa K, Kuge Y, Ogawa M, Kojima C.

International journal of pharmaceutics   576   2020.02

Diffuse leiomyomatosis with circumferential thickening of the gastrointestinal wall, resembling human diffuse leiomyomatosis, in a young miniature dachshund Reviewed

Kuramochi M, Izawa T, Mori M, Shimamura S, Shimada T, Kuwamura M, Yamate J.

The Journal of veterinary medical science   82 ( 2 )   139 - 142   2020.02

Pathological characteristics of Ccdc85c knockout rats: a rat model of genetic hydrocephalus. Reviewed

Konishi S, Tanaka N, Mashimo T, Yamamoto T, Sakuma T, Kaneko T, Tanaka M, Izawa T, Yamate J, Kuwamura M.

Experimental Animals 雑誌   69 ( 1 )   26 - 33   2020.01

Hepatic myoepithelial carcinoma in a dog: immunohistochemical comparison with other canine hepatic carcinomas. Reviewed

Tsuji Y, Kuramochi M, Izawa T, Akiyoshi H, Yamate J, Kuwamura M.

Veterinary Pathology 雑誌   56 ( 6 )   889 - 894   2019.11

Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy Reviewed

Wijesekera DP, Yuba E, De Silva NH, Watanabe S-I, Tsukamoto M, Ichida C, Izawa T, Itoh K, Kanegi R, Hatoya S, Yamate J, Inaba T, Sugiura K

FASEB BioAdvance 雑誌   2 ( 1 )   5 - 17   2019.11

Downregulation of aspartoacylase during the progression of myelin breakdown in the dmy mutant rat with mitochondrial magnesium channel MRS2 defect. Reviewed

Kuwamura M, Tanimura S, Hasegawa Y, Hoshiai R, Moriyama Y, Tanaka M, Takenaka S, Nagayoshi H, Izawa T, Yamate J, Kuramoto T, Serikawa T.

Brain Research 雑誌   1718   169 - 175   2019.09

Chronic kidney disease following 5/6 nephrectomy disturbs the intestinal microbiota and alters intestinal motility. Reviewed

Nishiyama K, Aono K, Fujimoto Y, Kuwamura M, Okada T, Tokumoto H, Izawa T, Okano R, Nakajima H, Takeuchi T, Azuma YT.

Journal of Cellular Physiology 雑誌   234   6667 - 6678   2019.05

Late onset of cerebellar cortical degeneration in a Magellanic penguin (Spheniscus magellanicus). Reviewed

Ioannidis M, Tanaka M, Yasui S, Kezuka C, Oyamada M, Hasegawa T, Izawa T, Yamate J, Kuwamura M.

The Journal of Veterinary Medical Science 雑誌   81   2019.05

Spontaneous peripheral neuritis in two electric eels (Electrophorus electricus). Reviewed

Rahman N, Kezuka C, Higashiguchi N, Kosaka N, Izawa T, Yamate J, Kuwamura M.

The Journal of Veterinary Medical Science 雑誌   81   2019.05

Chronic kidney disease after 5/6 nephrectomy disturbs the intestinal microbiota and alters intestinal motility Reviewed

Nishiyama K, Aono K, Fujimoto Y, Kuwamura M, Okada T, Tokumoto H, Izawa T, Okano R, Nakajima H, Takeuchi T, Azuma YT.

Journal of Cellular Physiology   234 ( 5 )   6667 - 6678   2019.05（ ISSN:00219541 ）

A case of feline T-cell lymphoma with tropism for striated muscle and peripheral nerve. Reviewed

Mori M, Izawa T, Sasaki H, Sonoyama J, Nishimura S, Shimamura S, Shimada T, Hasegawa T, Kuwamura M, Yamate J.

Journal of Comparative Pathology 雑誌   168   8 - 12   2019.04

Immunohistochemical characterization of myofibroblasts appearing in isoproterenol-induced rat myocardial fibrosis. Reviewed

Koga M, Kuramochi M, Karim MR, Izawa T, Kuwamura M, Yamate J.

The Journal of Veterinary Medical Science 雑誌   81   127 - 133   2019.01

The localization and distribution of cells labeled by a somatic stem cell-recognizing antibody (A3) in rat colon development; possible presence of a new cell type forming intestinal stem cell niche. Reviewed

Nishina H, Katou-Ichikawa C, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

Journal of Toxicologic Pathology 雑誌   32   37 - 48   2019.01

The localization and distribution of cells labeled by a somatic stem cell-recognizing antibody (A3) in rat colon development; possible presence of a new cell type forming the intestinal stem cell niche Reviewed

Nishina H, Katou-Ichikawa C, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

Journal of Toxicologic Pathology   32 ( 1 )   37 - 48   2019（ ISSN:09149198 ）

Expression of beta-catenin in regenerating renal tubules of cisplatin-induced kidney failure in rat Reviewed

Terada N, Karim MR, Izawa T, Kuwamura M, Yamate J

Clinical and Experimental Nephrology   22 ( 6 )   1240 - 1250   2018.12

Visualization of specific collagen-producing cells by Col1-GFP transgenic mice revealed novel type I collagen-producing cells other than fibroblasts in systemic organs/tissues Reviewed

Yamaguchi T, Kato Y, Okuda T, Rokushima M, Izawa T, Kuwamura M, Yamate J

Biochemical and Biophysical Research Communications   505 ( 1 )   267 - 273   2018.10

Dietary iron overload abrogates chemically-induced liver cirrhosis in rats Reviewed

Atarashi M, Izawa T, Mori M, Inai Y, Kuwamura M, Yamate J

Nutrients   10 ( 10 )   2018.10

Gene expression profile in retinal excitotoxicity induced by L-glutamate in neonatal rats Reviewed

Mitori H, Izawa T, Kuwamura M, Matsumoto M, Yamate J

Journal of Toxicologic Pathology   31 ( 4 )   301 - 306   2018.10

M1/M2-macrophage polarization-based hepatotoxicity in d-galactosamine-induced acute liver injury in rats Reviewed

Rahman N, Pervin M, Kuramochi M, Karim MR, Izawa T, Kuwamura M, Yamate J

Toxicologic Pathology   46 ( 7 )   764 - 776   2018.10

Comparison of acute gene expression profiles of islet cells obtained via laser capture microdissection between alloxan- and streptozotocin-treated rats Reviewed

Kato Y, Masago Y, Kondo C, Yogo E, Torii M, Hishikawa A, Izawa T, Kuwamura M, Yamate J

Toxicologic Pathology   46 ( 6 )   660 - 670   2018.08

Immunohistochemical analyses of the kinetics and distribution of macrophages in the developing rat kidney Reviewed

Matsuyama S, Karim MR, Izawa T, Kuwamura M, Yamate J

Journal of Toxicologic Pathology   31 ( 3 )   207 - 212   2018.07

Macrophage populations and expression of regulatory inflammatory factors in hepatic macrophage-depleted rat livers under lipopolysaccharide (LPS) treatment Reviewed

Pervin M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J

Toxicologic Pathology   46 ( 5 )   540 - 552   2018.07

Dietary iron supplementation alters hepatic inflammation in a rat model of nonalcoholic steatohepatitis Reviewed

Atarashi M, Izawa T, Miyagi R, Ohji S, Hashimoto A, Kuwamura M, Yamate J

Nutrients   10 ( 2 )   2018.02

The role of interleukin-19 in contact hypersensitivity Reviewed

Fujimoto Y, Fujita T, Kuramoto N, Kuwamura M, Izawa T, Nishiyama K, Yoshida N, Nakajima H, Takeuchi T, Azuma YT

Biological and Pharmaceutical Bulletin   41 ( 2 )   182 - 189   2018.02

Participation of tumor-associated myeloid cells in progression of amelanotic melanoma (RMM tumor line) in F344 rats, with particular reference to MHC class II- and CD163-expressing cells Reviewed

Bondoc A, Golbar HM, Pervin M, Katou-Ichikawa C, Tanaka M, Izawa T, Kuwamura M, Yamate J

Cancer Microenvironment   10 ( 1-3 )   9 - 24   2017.12

Immunophenotypical analysis of pancreatic interstitial cells in the developing rat pancreas and myofibroblasts in the fibrotic pancreas in dogs and cats Reviewed

Hashimoto A, Karim MR, Izawa T, Kuwamura M, Yamate J

The Journal of veterinary medical science   79 ( 12 )   1920 - 1926   2017.12

Ultrastructural features of canine neuroaxonal dystrophy in a Papillon dog Reviewed

Tanaka M, Yamaguchi S, Akiyoshi H, Tsuboi M, Uchida K, Izawa T, Yamate J, Kuwamura M

The Journal of veterinary medical science   79 ( 12 )   1927 - 1930   2017.12

Development of effective tumor immunotherapy using a novel dendritic cell-targeting Toll-like receptor ligand Reviewed

De Silva NH, Akazawa T, Wijewardana V, Inoue N, Oyamada M, Ohta A, Tachibana Y, Wijesekera DPH, Kuwamura M, Nishizawa Y, Itoh K, Izawa T, Hatoya S, Hasegawa T, Yamate J, Inaba T, Sugiura K

PLoS One   12 ( 11 )   2017.11

Immunolocalization of beta-catenin, E-cadherin and N-cadherin in neonate and adult rat kidney Reviewed

Terada N, Karim MR, Izawa T, Kuwamura M, Yamate J

The Journal of veterinary medical science   79 ( 11 )   1785 - 1790   2017.11

Attenuation of thioacetamide-induced hepatocellular injury by short-term repeated injections associated with down-regulation of metabolic enzymes and relationship with MHC class II-presenting cells Reviewed

Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, LaMarre J, Yamate J

Experimental and toxicologic pathology   69 ( 8 )   589 - 597   2017.10

Unilateral luteoma of the ovary in a pregnant Risso's dolphin (Grampus griseus) Reviewed

Nishina H, Izawa T, Ozaki M, Kuwamura M, Yamate J

The Journal of veterinary medical science   79 ( 10 )   1749 - 1752   2017.10

Characterization of pancreatic islet cell tumors and renal tumors induced by a combined treatment of streptozotocin and nicotinamide in male SD rats Reviewed

Kato Y, Masuno K, Fujisawa K, Tsuchiya N, Torii M, Hishikawa A, Izawa T, Kuwamura M, Yamate J

Experimental and toxicologic pathology   69 ( 7 )   397 - 403   2017.09

A case report of complete remission in feline gastric small B-cell lymphoma after helicobacter eradication therapy Reviewed

Tsuji M, Uemoto K, Kawasaki T, Ishizuka Y, Izawa T

Journal of the Japan Veterinary Medical Association   70 ( 8 )   523 - 528   2017.08

Spontaneous nephroblastoma with striated muscle differentiation in an F344 rat Reviewed

Tanaka N, Izawa T, Yamate J, Kuwamura M

Journal of Toxicologic Pathology   30 ( 3 )   231 - 234   2017.07

Pleomorphic adenoma of the labial gland, characterized by reticular pattern of myoepithelial cells in a dog Reviewed

Kuramochi M, Izawa T, Nishimura S, Shimada T, Kuwamura M, Yamate J

The Journal of veterinary medical science   79 ( 7 )   1163 - 1166   2017.07

Cutaneous histiocytic sarcoma with regional lymph node metastasis in a Netherland dwarf rabbit (Oryctolagus cuniculus) Reviewed

Karim MR, Izawa T, Pervin M, Sasai H, Kuwamura M, Yamate J

Journal of Comparative Pathology   156 ( 2-3 )   169 - 172   2017.07

Expression of Ccdc85C, a causative protein for murine hydrocephalus, in the mammary gland tumors of dogs Reviewed

Tanaka N, Izawa T, Takenaka S, Akiyoshi H, Yamate J, Kuwamura M

Histology and Histopathology   32 ( 4 )   397 - 403   2017.04

Attenuation of alpha-naphthylisothiocyanate (ANIT)-induced biliary fibrosis by depletion of hepatic macrophages in rats Reviewed

Golbar HM, Izawa T, Bondoc A, Wijesundera KK, Tennakoon AH, Kuwamura M, Yamate J

Experimental and toxicologic pathology   69 ( 4 )   221 - 230   2017.04

Interleukin-19 contributes as a protective factor in experimental Th2-mediated colitis Reviewed

Fujimoto Y, Azuma YT, Matsuo Y, Kuwamura M, Kuramoto N, Miki M, Azuma N, Teramoto M, Nishiyama K, Izawa T, Nakajima H, Takeuchi T

Naunyn-Schmiedeberg's Archives of Pharmacology   390 ( 3 )   261 - 268   2017.03

Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death Reviewed

Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, Azuma YT, Kuwamura M, Yamaji R, Takeuchi T

The Journal of Biological Chemistry   292 ( 11 )   4727 - 4742   2017.03

Enhanced expression of Trib3 during the development of myelin breakdown in dmy myelin mutant rats Reviewed

Shimotsuma Y, Tanaka M, Izawa T, Yamate J, Kuwamura M

PLoS One   11 ( 12 )   2016.12

Developing Stage-dependent Retinal Toxicity Induced by l-glutamate in Neonatal Rats Reviewed

Mitori H, Izawa T, Kuwamura M, Matsumoto M, Yamate J

Toxicologic Pathology   44 ( 8 )   1137 - 1145   2016.12

Hypogonadism alters cecal and fecal microbiota in male mice Reviewed

Harada N, Hanaoka R, Hanada K, Izawa T, Inui H, Yamaji R

Gut Microbes   7 ( 6 )   533 - 539   2016.11

Establishment and characterization of a transplantable tumor line (RMM) and cell line (RMM-C) from a malignant amelanotic melanoma in the F344 rat, with particular reference to galectin-3 expression in vivo and in vitro Reviewed

Bondoc A, Katou-Ichikawa C, Golbar HM, Tanaka M, Izawa T, Kuwamura M, Yamate J

Histology and Histopathology   31 ( 11 )   1195 - 1207   2016.11

Alteration of microRNA expressions in the pons and medulla in rats after 3,3'-iminodipropionitrile administration Reviewed

Ogata K, Kushida M, Miyata K, Sumida K, Takeda S, Izawa T, Kuwamura M, Yamate J

Journal of Toxicologic Pathology 雑誌   29 ( 4 )   229 - 236   2016.10

The kinetics of damage-associated molecular patterns (DAMPs) and toll-like receptors during thioacetamide-induced acute liver injury in rats Reviewed

Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, Yamate J

Experimental and toxicologic pathology   68 ( 8 )   471 - 477   2016.09

Metastatic Liposarcoma in a South African Fur Seal (Arctocephalus pusillus) Reviewed

Pervin M, Izawa T, Ito S, Kuwamura M, Yamate J

Journal of Comparative Pathology   155 ( 1 )   72 - 75   2016.08

M1-/M2-macrophage polarization in pseudolobules consisting of adipohilin-rich hepatocytes in thioacetamide (TAA)-induced rat hepatic cirrhosis. Reviewed

Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J

Experimental and Molecular Pathology   101 ( 1 )   133 - 142   2016.08

Detection of multiple budding yeast cells and a partial sequence of 43-kda glycoprotein coding gene of paracoccidioides brasiliensis from a case of lacaziosis in a female pacific white-sided dolphin (Lagenorhynchus obliquidens) Reviewed

Minakawa T, Ueda K, Tanaka M, Tanaka N, Kuwamura M, Izawa T, Konno T, Yamate J, Itano EN, Sano A, Wada S

Mycopathologia   181 ( 7-8 )   523 - 529   2016.08

Multiple histiocytic foam cell nodules in the tongue of miniature dachshund dogs Reviewed

Katou-Ichikawa C, Izawa T, Sasai H, Kuwamura M, Yamate J

Veterinary Pathology   53 ( 3 )   625 - 628   2016.05

Transient effects of empty liposomes on hepatic macrophage populations in rats Reviewed

Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J

Journal of Toxicologic Pathology   29 ( 2 )   139 - 144   2016.04

Immunophenotypical characterization and influence on liver homeostasis of depleting and repopulating hepatic macrophages in rats injected with clodronate Reviewed

Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J

Experimental and toxicologic pathology   68 ( 2-3 )   113 - 124   2016.02

Depletion of hepatic macrophages aggravates liver lesions induced in rats by thioacetamide (TAA) Reviewed

Golbar HM, Izawa T, Wijesundera KK, Bondoc A, Tennakoon AH, Kuwamura M, Yamate J

Toxicologic Pathology   44 ( 2 )   246 - 258   2016.02

Rat malignant fibrous histiocytoma (MFH)-derived cloned cell lines (MT-8 and MT-9) show different differentiation in mesenchymal stem cell lineage Reviewed

Kotera T, Katou-Ichikawa C, Tennakoon AH, Tanaka M, Tanaka N, Izawa T, Kuwamura M, Yamate J

Experimental and toxicologic pathology   67 ( 10 )   499 - 507   2015.10

pH-sensitive polymer-liposome-based antigen delivery systems potentiated with interferon-gamma gene lipoplex for efficient cancer immunotherapy Reviewed

Yuba E, Kanda Y, Yoshizaki Y, Teranishi R, Harada A, Sugiura K, Izawa T, Yamate J, Sakaguchi N, Koiwai K, Kono K

Biomaterials   67   214 - 224   2015.10

M1-/M2-macrophages contribute to the development of GST-P-positive preneoplastic lesions in chemically-induced rat cirrhosis Reviewed

Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J

Experimental and toxicologic pathology   67 ( 9 )   467 - 475   2015.09

Anti-fibrotic role of miR-214 in thioacetamide-induced liver cirrhosis in rats Reviewed

Izawa T, Horiuchi T, Atarashi M, Kuwamura M, Yamate J

Toxicologic Pathology   43 ( 6 )   844 - 851   2015.08

Ccdc85C, a causative protein for hydrocephalus and subcortical heterotopia, is expressed in the systemic epithelia with proliferative activity in rats Reviewed

Tanaka N, Izawa T, Takenaka S, Yamate J, Kuwamura M.

Histology and Histopathology   30 ( 7 )   823 - 832   2015.07

Chordoma of the thoracic vertebrae in a Bengal tiger (Panthera tigris tigris) Reviewed

Kuramochi M, Izawa T, Hori M, Kusuda K, Shimizu J, Iseri T, Akiyoshi H, Ohashi F, Kuwamura M, Yamate J

The Journal of veterinary medical science   77 ( 7 )   893 - 895   2015.07

Computed tomography and magnetic resonance imaging of thoracic chordoma in a Bengal tiger (Panthera tigris tigris). Reviewed

Iseri T, Shimizu J, Akiyoshi H, Kusuda K, Hayashi A, Mie K, Izawa T, Kuwamura M, Yamate J, Fujimoto Y, Ohashi F

The Journal of veterinary medical science   77 ( 7 )   857 - 860   2015.07

Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic beta-cells Reviewed

Harada N, Katsuki T, Takahashi Y, Masuda T, Yoshinaga M, Adachi T, Izawa T, Kuwamura M, Nakano Y, Yamaji R, Inui H.

Journal of Cell Biology   116 ( 6 )   998 - 1006   2015.06

Analysis of glial fibrillary acidic protein (GFAP)-expressing ductular cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA) Reviewed

Tennakoon AH, Izawa T, Wijesundera KK, Katou-Ichikawa C, Tanaka M, Golbar HM, Kuwamura M, Yamate J.

Experimental and Molecular Pathology   98 ( 3 )   476 - 485   2015.06

Participation of bone morphogenetic protein (BMP)-6 and osteopontin in cisplatin (CDDP)-induced rat renal fibrosis Reviewed

Yano R, Golbar HM, Izawa T, Sawamoto O, Kuwamura M, Yamate J.

Experimental and toxicologic pathology   67 ( 2 )   99 - 107   2015.02

Immunohistochemical characterization of glial fibrillary acidic protein (GFAP)-expressing cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA) Reviewed

Tennakoon AH, Izawa T, Wijesundera KK, Murakami H, Katou-Ichikawa C, Tanaka M, Golbar HM, Kuwamura M, Yamate J.

Experimental and toxicologic pathology   67 ( 1 )   53 - 63   2015.01

Amphotericin B induces glial cell line-derived neurotrophic factor in rat brain. Reviewed

Motoyoshi-Yamashiro A, Takano K, Kawabe K, Izawa T, Nakajima H, Nakamura Y.

The Journal of veterinary medical science   76 ( 10 )   2014.10

Characterization of rat testicular teratoma and its derived cell lines, with particular reference to possible mesenchymal differentiations. Reviewed

Yamate, J. Gamou, K. Izawa-Ogata, K. Kotera, T. Izawa, T. Takenaka, S. Sawamoto, O. Kuwamura, M.

Histology and Histopathology   29 ( 9 )   1201 - 1216   2014.09

The VF rat with abnormal myelinogenesis has a mutation in Dopey1. Reviewed

Tanaka, M. Izawa, T. Yamate, J. Franklin, R. J. Kuramoto, T. Serikawa, T. Kuwamura, M.

Glia   62 ( 9 )   1530 - 1542   2014.09

Involvement of neutrophil gelatinase-associated lipocalin and osteopontin in renal tubular regeneration and interstitial fibrosis after cisplatin-induced renal failure. Reviewed

Kashiwagi E, Tonomura Y, Kondo C, Masuno K, Fujisawa K, Tsuchiya N, Matsushima S, Torii M, Takasu N, Izawa T, Kuwamura M, Yamate J.

Experimental and toxicologic pathology   66 ( 7 )   301 - 311   2014.09

Myoepithelioma of the gland of the third eyelid in a dog. Reviewed

Bondoc, A. Izawa, T. Hirata, S. Hasegawa, T. Kuwamura, M. Golbar, H. M. Yamate, J.

Journal of Comparative Pathology   151 ( 2-3 )   186 - 189   2014.08

Expression of nestin in remodelling of alpha-naphthylisothiocyanate-induced acute bile duct injury in rats Reviewed

Golbar HM, Izawa T, Wijesundera KK, Tennakoon AH, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J

Journal of Comparative Pathology   151 ( 2-3 )   255 - 263   2014.08

A collision tumour consisting of malignant trichoblastoma and melanosarcoma in a rabbit. Reviewed

Golbar HM, Izawa T, Kuwamura M, Fujita D, Sasai H, Yamate J.

Journal of Comparative Pathology   151 ( 1 )   63 - 66   2014.07

Calponin expression in renal tubulointerstitial fibrosis induced in rats by Cisplatin. Reviewed

Yuasa T, Yano R, Izawa T, Kuwamura M, Yamate J.

Journal of Toxicologic Pathology   27 ( 1 )   97 - 103   2014.04

The first case of infectious spleen and kidney necrosis virus (ISKNV) infection in aquarium-maintained mandarin fish, Siniperca chuatsi (Basilewsky), in Japan. Reviewed

Tanaka N, Izawa T, Kuwamura M, Higashiguchi N, Kezuka C, Kurata O, Wada S, Yamate J.

Journal of Fish Diseases   37 ( 4 )   401 - 405   2014.04

Phaeochromocytoma and hepatocellular carcinoma with nuclear glycogenation of the hepatocytes in a predatory carp, Chanodichthys erythropterus (Basilewsky). Reviewed

Tanaka N, Izawa T, Kuwamura M, Higashiguchi N, Kezuka C, Yamate J.

Journal of Fish Diseases   37 ( 4 )   411 - 414   2014.04

M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology. Reviewed

Wijesundera KK, Izawa T, Murakami H, Tennakoon AH, Golbar HM, Kato-Ichikawa C, Tanaka M, Kuwamura M, Yamate J.

Histology and Histopathology   29 ( 4 )   497 - 511   2014.04

M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-3. Reviewed

Wijesundera KK, Izawa T, Tennakoon AH, Murakami H, Golbar HM, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J.

Experimental and Molecular Pathology   96 ( 3 )   382 - 392   2014.04

Evaluation of Serum Phosphorylated Neurofilament Subunit NF-H as a Prognostic Biomarker in Dogs With Thoracolumbar Intervertebral Disc Herniation. Reviewed

Nishida H, Nakayama M, Tanaka H, Kamishina H, Izawa T, Hatoya S, Sugiura K, Suzuki Y, Ide C, Inaba T.

Veterinary Surgery   43 ( 3 )   289 - 293   2014.03

Inflammatory regulation of iron metabolism during thioacetamide-induced acute liver injury in rats. Reviewed

Izawa T, Murakami H, Wijesundera KK, Golbar HM, Kuwamura M, Yamate J.

Experimental and toxicologic pathology   66 ( 41673 )   155 - 162   2014.03

A case of meconium aspiration syndrome in a bottlenose dolphin (Tursiops truncatus) calf. Reviewed

Tanaka M, Izawa T, Kuwamura M, Ozaki M, Nakao T, Ito S, Yamate J.

The Journal of veterinary medical science   76 ( 1 )   81 - 84   2014.02

Primary cerebral T-cell lymphoma in a sea otter (enhydra lutris). Reviewed

Tanaka N, Izawa T, Kashiwagi-Yamamoto E, Kuwamura M, Ozaki M, Nakao T, Yamate J.

The Journal of veterinary medical science   75 ( 12 )   1667 - 1669   2013.12

Combined hepatocellular-cholangiocarcinoma in a yellow-headed amazon (Amazona oratrix) Reviewed

Tennakoon, A. H. Izawa, T. Fujita, D. Denda, Y. Seto, E. Sasai, H. Kuwamura, M. Yamate, J.

The Journal of veterinary medical science   75 ( 11 )   1507 - 1510   2013.11

Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury Reviewed

Tennakoon, A. H. Izawa, T. Wijesundera, K. K. Golbar, H. M. Tanaka, M. Ichikawa, C. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   65 ( 41828 )   1159 - 1171   2013.11

Spontaneous extraskeletal osteosarcoma in a rabbit (Oryctolagus cuniculus): histopathological and immunohistochemical findings. Reviewed

Wijesundera, K. K. Izawa, T. Fujita, D. Denda, Y. Seto, E. Sasai, H. Kuwamura, M. Yamate, J.

Journal of Toxicologic Pathology   26 ( 3 )   309 - 312   2013.09

Two cases of lacaziosis in bottlenose dolphins (Tursiops truncates) in Japan. Reviewed

Ueda, K. Sano, A. Yamate, J. Itano, E. Kuwamura, M. Izawa, T. Tanaka, M. Hasegawa, Y. Chibana, H. Izumisawa, Y. Miyahara, H. Uchida, S.

Case Reports in Veterinary Medicine   2013.09

Expressions of Iba1 and galectin-3 (Gal-3) in thioacetamide (TAA)-induced acute rat liver lesions Reviewed

Wijesundera, K. K. Juniantito, V. Golbar, H. M. Fujisawa, K. Tanaka, M. Ichikawa, C. Izawa, T. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   65 ( 6 )   799 - 808   2013.09

Slowly progressive cholangiofibrosis induced in rats by alpha-naphthylisothiocyanate (ANIT), with particular references to characteristics of macrophages and myofibroblasts Reviewed

Golbar, H. M. Izawa, T. Ichikawa, C. Tanaka, M. Juniantito, V. Sawamoto, O. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   65 ( 6 )   825 - 835   2013.09

A case of canine seminoma that metastasized to a medial iliac lymph node and was treated with preoperative irradiation and surgical resection Reviewed

Yamamoto, R. Akiyoshi, H. Hukui, H. Hirata, S. Izawa, T. Ohashi, F. Kubo, K.

Journal of the Japan Veterinary Medical Association   66   553 - 556   2013.08

Thy-1 expression, a possible marker of early myofibroblast development, in renal tubulointerstitial fibrosis induced in rats by cisplatin Reviewed

Yuasa, T. Juniantito, V. Ichikawa, C. Yano, R. Izawa, T. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   65 ( 5 )   651 - 659   2013.07

Expression patterns of heat shock protein 25 in carbon tetrachloride-induced rat liver injury Reviewed

Fujisawa, K. Yabuuchi, C. Izawa, T. Kuwamura, M. Takasu, N. Torii, M. Yamate, J.

Experimental and toxicologic pathology   65 ( 5 )   469 - 76   2013.07

Immunohistochemical characterization of macrophages and myofibroblasts in fibrotic liver lesions due to fasciola infection in cattle Reviewed

Golbar, H. M. Izawa, T. Juniantito, V. Ichikawa, C. Tanaka, M. Kuwamura, M. Yamate, J.

The Journal of veterinary medical science   75 ( 7 )   857 - 865   2013.07

Immunophenotypical analysis of myofibroblasts and mesenchymal cells in the bleomycin-induced rat scleroderma, with particular reference to their origin Reviewed

Juniantito, V. Izawa, T. Yuasa, T. Ichikawa, C. Tanaka, M. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   65 ( 5 )   567 - 577   2013.07

Generation of functional platelets from canine induced pluripotent stem cells Reviewed

Nishimura, T. Hatoya, S. Kanegi, R. Sugiura, K. Wijewardana, V. Kuwamura, M. Tanaka, M. Yamate, J. Izawa, T. Takahashi, M. Kawate, N. Tamada, H. Imai, H. Inaba, T.

Stem Cells and Development   22 ( 14 )   2026 - 2035   2013.07

Distribution of cells labelled by a novel somatic stem cell-recognizing antibody (A3) in pulmonary genesis and bleomycin induced pulmonary fibrosis in rats Reviewed

Hori, M. Juniantito, V. Izawa, T. Ichikawa, C. Tanaka, M. Tanaka, K. Takenaka, S. Kuwamura, M. Yamate, J.

Journal of Comparative Pathology   148 ( 4 )   385 - 395   2013.05

Pulmonary dystrophic oxalosis and its possible relation to fibrosis in an aged gentoo penguin (Pygoscelis papua) Reviewed

Wijesundera, K.K. Izawa, T. Tanaka, M. Nakao, T. Maezono, Y. Ito, S. Kuwamura, M. Yamate, J.

The Journal of veterinary medical science   75 ( 3 )   365 - 368   2013.04

Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis Reviewed

Uehara, T. Ainslie, G.R. Kutanzi, K. Pogribny, I.P. Muskhelishvili, L. Izawa, T. Yamate, J. Kosyk, O. Shymonyak, S. Bradford, B.U. Boorman, G.A. Bataller, R. Rusyn, I.

Toxicological sciences   132 ( 1 )   53 - 63   2013.03

Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: Reviewed

Ichikawa, C. Izawa, T. Juniantito, V. Tanaka, M. Hori, M. Tanaka, K. Takenaka, S. Kuwamura, M. Yamate, J.

Histology and Histopathology   28 ( 2 )   257 - 268   2013.02

Immunophenotypical characterization of macrophages in rat bleomycin-induced scleroderma Reviewed

Juniantito, V. Izawa, T. Yuasa, T. Ichikawa, C. Yano, R. Kuwamura, M. Yamate, J.

Veterinary Pathology   50 ( 1 )   76 - 85   2013.01

Abnormal myelinogenesis in the central nervous system of the VF mutant rat with recoverable tremor Reviewed

Tanaka, M. Soma, K. Izawa, T. Yamate, J. Franklin, R.J. Kuramoto, T. Serikawa, T. Kuwamura. M.

Brain Research   1488   104 - 112   2012.12

Incidental synovial myxoma with extensive intermuscular infiltration in a dog Reviewed

Izawa, T. Tanaka, M. Aoki, M. Ohashi, F. Yamate, J. Kuwamura, M.

The Journal of veterinary medical science   74 ( 12 )   1631 - 1633   2012.12

Amelioration of cisplatin-induced rat renal lesions by a cyclooxygenase (COX)-2 selective inhibitor Reviewed

Yamamato, E. Izawa, T. Sawamoto, O. Juniantito, V. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   64 ( 6 )   625 - 631   2012.09

Deep granulomatous dermatitis of the fin caused by Fusarium solani in a false killer whale (Pseudorca crassidens) Reviewed

Tanaka, M. Izawa, T. Kuwamura, M. Nakao, T. Maezono, Y. Ito, S. Murata, M. Murakami, M. Sano, A. Yamate, J.

The Journal of veterinary medical science   74 ( 6 )   779 - 782   2012.07

Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts Reviewed

Juniantito, V. Izawa, T. Yuasa, T. Ichikawa, C. Yamamoto, E. Kuwamura, M. Yamate, J.

Histology and Histopathology   27 ( 4 )   515 - 527   2012.04

A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain Reviewed

Nakajima, H. Kubo, T. Semi, Y. Itakura, M. Kuwamura, M. Izawa, T. Azuma, Y.T. Takeuchi, T.

Journal of Biotechnology   157 ( 2 )   326 - 333   2012.01

Immunohistochemical analyses of the kinetics and distribution of macrophages, hepatic stellate cells and bile duct epithelia in the developing rat live Reviewed

Golbar, H. M. Izawa, T. Murai, F. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   64 ( 41641 )   2012.01

Immunohistochemical expressions of main PGE2 biosynthesis-related enzymes and PGE2 receptor in rat nephrogenesis Reviewed

Yamamoto, E. Izawa, T. Kuwamura, M. Yamate, J.

Journal of Toxicologic Pathology   24 ( 4 )   257 - 261   2011.12

A collision tumor consisting of granular cell tumor and adenocarcinoma in the uterus of an aged djungarian hamster Reviewed

Golbar, H.M. Izawa, T. Kuwamura,M. Okamura, K. Fujita, D. Tagami, Y. Sasai, H. Yamate, J.

Journal of Toxicologic Pathology   24 ( 4 )   233 - 237   2011.12

Heterogeneity of macrophage populations and expression of galectin-3 in cutaneous wound healing in rats Reviewed

Juniantito, V. Izawa, T. Yamamato, E. Murai, F. Kuwamura, M. Yamate, J.

Journal of Comparative Pathology   145 ( 4 )   378 - 389   2011.11

A rhabdomyosarcoma arising in the larynx of a dog Reviewed

Yamate, J. Murai, F. Izawa, T. Akiyoshi, H. Shimizu, J. Ohashi, F. Kuwamura, M.

Journal of Toxicologic Pathology   24 ( 3 )   179 - 182   2011.09

Relationship of heat shock protein 25 with reactive macrophages in thioacetamide-induced rat liver injury Reviewed

Fujisawa, K. Miyoshi, T. Tonomura, Y. Izawa, T. Kuwamura, M. Torii, M. Yamate, J.

Experimental and toxicologic pathology   63 ( 6 )   599 - 605   2011.09

Cardiac hamartoma in a young squirrel monkey who died suddenly Reviewed

Golbar, H. M. Izawa, T. Kuwamura, M. Fujita, D. Okamura, K. Yamazaki, R. Tagami, Y. Sasai, H. Yamate, J.

Veterinary Pathology   48 ( 5 )   970 - 974   2011.09

Immunohistochemical characterization of macrophages and myofibroblasts in α-aphthylisothiocyanate (ANIT)-induced bile duct injury and subsequent fibrogenesis in rats Reviewed

Glober, H.M. Izawa, T. Yano, R. Ichikawa, C. Sawamoto, O. Kuwamura, M. LaMarre, J. Yamate, J.

Toxicologic Pathology   39 ( 5 )   795 - 808   2011.08

Oligodendroglial pathology in the development of myelin breakdown in the dmy mutant rat Reviewed

Kuwamura, M. Inumaki, K. Tanaka, M. Shirai, M. Izawa, T. Yamate, J. Franklin, R. J. Kuramoto, T. Serikawa, T.

Brain Research   1389   161 - 168   2011.05

Encapsulating peritoneal sclerosis associated with abnormal liver development in a young dog Reviewed

Izawa, T. Murai, F. Akiyoshi, H. Ohashi, F. Yamate, J. Kuwamura, M.

The Journal of veterinary medical science   73 ( 5 )   697 - 700   2011.05

Comparative gene expression analysis in the skeletal muscles of dysferlin-deficient SJL/J and A/J mice. Reviewed

Kobayashi, K. Izawa, T. Kuwamura, M. Yamate, J.

Journal of Toxicologic Pathology   24   49 - 62   2011.04

A mutation in the gene encoding mitochondrial Mg(2)+ channel MRS2 results in demyelination in the rat Reviewed

Kuramoto, T. Kuwamura, M. Tokuda, S. Izawa, T. Nakane, Y. Kitada, K. Akao, M. Guenet, J. L. Serikawa, T.

PLoS genetics   7 ( 1 )   2011.01

Relationship of cell proliferating marker expressions with PGE2 receptors in regenerating rat renal tubules after cisplatin injection Reviewed

Yamamoto, E. Izawa, T. Juniantito, V. Kuwamura, M. Yamate, J.

Journal of Toxicologic Pathology   23 ( 4 )   271 - 275   2011.01

Relationship of Cell Proliferating Marker Expressions with PGE(2) Receptors in Regenerating Rat Renal Tubules after Cisplatin Injection Reviewed

Yamamoto E, Izawa T, Juniantito V, Kuwamura M, Yamate J.

Journal of Toxicologic Pathology 雑誌   23 ( 4 )   271 - 275   2010.12

The distribution and characterization of skeletal muscle lesions in dysferlin-deficient SJL and A/J mice Reviewed

Kobayashi, K. Izawa, T. Kuwamura, M. Yamate, J.

Experimental and toxicologic pathology   62 ( 5 )   509 - 517   2010.09

Involvement of endogenous prostaglandin E2 in tubular epithelial regeneration through inhibition of apoptosis and epithelial-mesenchymal transition in cisplatin-induced rat renal lesions Reviewed

Yamamoto, E. Izawa, T. Juniantito, V. Kuwamura, M. Sugiura, K. Takeuchi, T. Yamate, J.

Histology and Histopathology   25 ( 8 )   995 - 1007   2010.08

Abnormal iron accumulation is involved in the pathogenesis of the demyelinating dmy rat but not in the hypomyelinating mv rat Reviewed

Izawa, T. Yamate, J. Franklin, R. J. Kuwamura, M.

Brain Research   1349   105 - 114   2010.08

The kinetics and distribution of different macrophage populations in the developing rat skin Reviewed

Juniantito, V. Izawa, T. Yamamoto, E. Kuwamura, M. Yamate, J.

Histology and Histopathology   25 ( 8 )   985 - 94   2010.08

Thy-1 expressing mesenchymal cells in rat nephrogenesis, in correlation with cells immunoreactive for a-smooth muscle actin and vimentin Reviewed

Yuasa, T. Izawa, T. Kuwamura, M. Yamate, J.

Journal of Toxicologic Pathology   23 ( 1 )   2010.04

Abnormal myelinogenesis both in the white and gray matter of the attractin-deficient mv rat Reviewed

Izawa, T. Yamate, J. Franklin, R. J. Kuwamura, M.

Brain Research   1312   145 - 155   2010.02

Uterine adenocarcinoma with prominent desmoplasia in a geriatric miniature pig Reviewed

Golbar, H. Izawa, T. Kuwamura, M. Ito, S. Yamate, J.

The Journal of veterinary medical science   72 ( 2 )   253 - 256   2010.02

Gastrointestinal candidiasis in an Aldabra giant tortoise (Geochelone gigantea) Reviewed

Juniantito, V. Izawa, T. Kuwamura, M. Yonezawa, M. Ito, S. Yamate, J.

The Journal of veterinary medical science   71 ( 9 )   1269 - 1272   2009.09

Participation of functionally different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury Reviewed

Mori, Y. Izawa, T. Takenaka, S. Kuwamura, M. Yamate, J.

Toxicologic Pathology   37 ( 4 )   463 - 473   2009.06

Malignant seminoma with multiple visceral metastases in a guinea fowl (Numida meleagris) kept in a zoo Reviewed

Golbar, H. M. Izawa, T. Kuwamura, M. Yonezawa, M. Ito, S. Yamate, J.

Avian Diseases   53 ( 1 )   143 - 145   2009.05

Vasoformative disorder, resembling littoral cell angioma, of the spleen in a geriatric Japanese macaque (Macaca fuscata) Reviewed

Yamate, J. Izawa, T. Kuwamura, M. Mitsunaga, F. Nakamura, S.

Veterinary Pathology   46 ( 3 )   520 - 525   2009.05

Macrophage populations and expressions of regulatory proinflammatory factors in the rat meninx under lipopolysaccharide treatment in vivo and in vitro Reviewed

Yamate, J. Ishimine, S. Izawa, T. Kumagai, D. Kuwamura, M.

Histology and Histopathology   24 ( 1 )   13 - 24   2009.01

Cutaneous rhabdoid tumor in a cat Reviewed

Izawa, T. Yamate, J. Takeda, S. Kumagai, D. Kuwamura, M.

Veterinary Pathology   45 ( 6 )   897 - 900   2008.11

Cellular responses in the spinal cord during development of hypomyelination in the mv rat Reviewed

Izawa, T. Takenaka, S. Ihara, H. Kotani, T. Yamate, J. Franklin, R. J. Kuwamura, M.

Brain Research   1195   120 - 129   2008.02

Olfactory neuroblastoma in a horse Reviewed

Yamate, J. Izawa, T. Ogata, K. Kobayashi, O. Okajima, R. Kuwamura, M. Kotani, T. Aoki, M.

The Journal of veterinary medical science   68 ( 5 )   495 - 498   2006.05

Dysferlin and animal models for dysferlinopathy Reviewed

Kobayashi K, Izawa T, Kuwamura M, Yamate J

Journal of Toxicologic Pathology   25 ( 2 )   135 - 147   2012.06

アルデヒド脱水素酵素2型遺伝子多型によるアリルアルコール誘発肝毒性の増悪機序の解析 Domestic conference

高見 優生，中村 純，田中 美有，桑村 充，岡田 利也，井澤 武史

第40回日本毒性病理学会総会及び学術集会  2024.01  日本毒性病理学会

Dual role of the Keap1-Nrf2 system in a rat liver cirrhosis model that is influenced by hepatic iron condition International conference

Takeshi IZAWA , Nanako HAMADA , Yuri ITO , Keiko TAGUCHI , Masayuki YAMAMOTO , Mitsuru KUWAMURA.

The Environmental Response VI  2023.11  The Environmental Response VI

化合物誘発肝障害における食餌性肝鉄過剰およびビタミン K による病態修飾機構の解明. Domestic conference

瓶井 知美、井澤 武史、稲井 洋平、森 睦月、藤原 奨、田中 美有、桑村 充.

第47回日本鉄バイオサイエンス学会学術集会  2023.09  日本鉄バイオサイエンス学会

代謝異常性鉄過剰症(DIOS)モデルラットを用いたメタボリックシンドロームにおけ る鉄の病態修飾機序の検討 Domestic conference

藤原 咲春、井澤 武史、森 睦貴、新 真智、山手 丈至、桑村 充.

第47回日本鉄バイオサイエンス学会学術集会  2023.09  日本鉄バイオサイエンス学会

Decreased susceptibility to chemically-induced acute liver injury in chimeric mice with humanized liver Invited Domestic conference

Takeshi Izawa

JSOT2023（The 50th Annual Meeting of the Japanese Society of Toxicology）  2023.06  The Japanese Society of Toxicology (JSOT)

獣医科学英語演習

2024   Intensive lecture   Undergraduate

獣医病理組織学実習

2024   Weekly class   Undergraduate

獣医病理学A

2024   Weekly class   Undergraduate

臨床基礎実習

2024   Weekly class   Undergraduate

獣医病理学A

2024   Weekly class   Undergraduate

獣医病理組織学実習

2024   Weekly class   Undergraduate

獣医体験演習

2024   Weekly class   Undergraduate

分子病理学特論

2024   Intensive lecture   Graduate school

統合生体学特別講義B

2024   Intensive lecture   Graduate school

臨床基礎実習

2024   Weekly class   Undergraduate

毒性病理学実習

2024   Intensive lecture   Undergraduate

疾患モデル動物学

2024   Intensive lecture   Undergraduate

獣医病理診断学実習

2024   Weekly class   Undergraduate

獣医病理学B

2024   Weekly class   Undergraduate

生物学実験

2024   Intensive lecture   Graduate school

獣医病理組織学実習

2022   Weekly class   Undergraduate

獣医病理学A

2022   Weekly class   Undergraduate

獣医科学特別演習1

2022   Intensive lecture   Graduate school

小動物基礎臨床実習

2022   Intensive lecture   Undergraduate

毒性病理学

2022   Intensive lecture   Undergraduate

疾患モデル動物学

2022   Intensive lecture   Undergraduate

毒性病理学実習

2022   Intensive lecture   Undergraduate

臨床基礎実習

2022   Weekly class   Undergraduate

獣医体験演習

2022   Weekly class   Undergraduate

獣医科学特別演習1

2022   Intensive lecture   Graduate school

分子病理学特論

2022   Intensive lecture   Graduate school

国際・国内インターンシップ

2022   Intensive lecture   Graduate school

獣医科学特別研究1

2022   Intensive lecture   Graduate school

獣医科学特別研究1

2022   Intensive lecture   Graduate school

生物学実験

2022   Intensive lecture   Undergraduate

生物学A獣医

2022   Intensive lecture   Undergraduate

獣医病理学B

2022   Weekly class   Undergraduate

獣医病理診断学実習

2022   Weekly class   Undergraduate

Biology A

2021    

Special Lecture: Integrated Structural Biosciences B

2021    

Practice in Toxicologic Pathology

2021   Practical Training  

Toxicologic Pathology

2021    

Pathological Animal Model Science

2021    

Fundamental Experiments of Biology

2021   Practical Training  

Veterinary Pathology A

2021    

Veterinary Pathology B

2021    

Practice in Veterinary Pathological Diagnosis

2021   Practical Training  

Basic clinical practices

2021   Practical Training  

Practice in Veterinary Histopathology

2021   Practical Training