2022/07/13 更新

写真a

イザワ タケシ
井澤 武史
Izawa Takeshi
担当
大学院獣医学研究科 獣医学専攻 准教授
獣医学部 獣医学科
職名
准教授
所属
獣医学研究院
連絡先
メールアドレス

担当・職階

  • 大学院獣医学研究科 獣医学専攻 

    准教授  2022年04月 - 継続中

  • 獣医学部 獣医学科 

    准教授  2022年04月 - 継続中

取得学位

  • 獣医学博士 ( 大阪府立大学 )

研究分野

  • ライフサイエンス / 獣医学  / 獣医病理学

研究キーワード

  • 獣医病理学,比較病理学,診断病理学,毒性病理学,実験病理学,分子病理学,肝臓病理学

研究概要

  • 薬剤性肝障害の分子メカニズム解明(Elucidation of the molecular mechanism for drug-induced liver injury)

  • 慢性肝疾患における病態進展機構の解明(Elucidation of the mechanism underlying progression of chronic liver diseases)

研究歴

  • 肝疾患における鉄過剰の病態修飾機構の解明

    慢性肝疾患、鉄過剰、非アルコール性脂肪性肝疾患、薬剤性肝傷害  個人研究

    2010年04月 - 継続中 

所属学協会

  • 日本鉄バイオサイエンス学会

    2019年07月 - 継続中   国内

  • 日本毒性学会

    2014年03月 - 継続中   国内

  • 日本獣医病理学専門家協会

    2012年04月 - 継続中   国内

  • 日本獣医病理学会

    2008年12月 - 継続中   国内

  • 日本毒性病理学会

    2006年09月 - 継続中   国内

  • 日本獣医学会

    2005年03月 - 継続中   国内

▼全件表示

受賞歴

  • 2020年グッドレビュワー賞

    2021年09月   日本獣医学会  

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    受賞国:日本国

  • 2019年グッドレビュワー賞

    2020年09月   日本獣医学会  

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    受賞国:日本国

  • 日本鉄バイオサイエンス学会学術奨励賞

    2019年09月   日本鉄バイオサイエンス学会  

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    受賞国:日本国

  • 日本獣医病理学会優秀論文賞

    2011年03月   日本獣医病理学会  

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    受賞国:日本国

  • 第145回日本獣医学会学術集会ベストプレゼンテーション賞

    2008年03月   日本獣医学会  

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    受賞国:日本国

職務経歴(学外)

  • 准教授

    2015年04月 - 継続中

  • 助教

    2010年04月 - 2015年03月

学歴

  • 大阪府立大学   生命環境科学研究科   獣医学専攻   博士課程   卒業・修了

    2006年04月 - 2010年03月

  • 大阪府立大学   農学部   獣医学科   その他   卒業・修了

    2000年04月 - 2006年03月

論文

  • Expression of CCDC85C, a causative protein for hydrocephalus, and intermediate filament proteins during lateral ventricle development in rats 査読

    Hasan MM, Konishi S, Tanaka M, Izawa T, Yamate J, Kuwamura M.

    Experimental Animals   2022年

  • Possible cytoprotection of low dose lipopolysaccharide in rat thioacetamide-induced liver lesions, focusing on the analyses of hepatic macrophages and autophagy 査読

    Pervin M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

    Toxicologic Pathology   2022年

  • IL-19 contributes to the development of nonalcoholic steatohepatitis by altering lipid metabolism 査読

    Azuma YT, Fujita T, Izawa T, Hirota K, Nishiyama K, Ikegami A, Aoyama T, Ike M, Ushikai Y, Kuwamura M, Fujii H, Tsuneyama K.

    Cells   10 ( 12 )   2021年12月

  • Systemic anaplastic large T-cell lymphoma with initial presentation of dysuria in a dog 査読

    Kaneguchi A, Izawa T, Tanaka M, Suzuki H, Tani H, Kuwamura M, Yamate J

    Journal of Comparative Pathology   189   26 - 30   2021年11月

  • Properties of macrophages and lymphocytes appearing in rat renal fibrosis followed by repeated injection of cisplatin 査読

    Matsuyama S, Pervin M, Nakagawa M, Izawa T, Kuwamura M, Yamate J.

    The Journal of veterinary medical science   83 ( 9 )   1435 - 1442   2021年09月

  • leamide rescues tibialis anterior muscle atrophy of mice housed in small cages 査読

    Kobayashi Y, Watanabe N, Kitakaze T, Sugimoto K, Izawa T, Kai K, Harada, N, Yamaji R.

    British Journal of Nutrition   126 ( 4 )   481 - 491   2021年08月

  • Appearance of heterogeneous macrophages during development of isoproterenol-induced rat myocardial fibrosis 査読

    Koga M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

    Toxicologic Pathology   49 ( 5 )   2021年07月

  • Involvement of neutrophils in rat livers by low-dose thioacetamide administration 査読

    Kuramochi M, Izawa T, Kuwamura M, Yamate J.

    The Journal of veterinary medical science   83 ( 3 )   390 - 396   2021年03月

  • PHF24 is expressed in the inhibitory interneurons in rats 査読

    Numakura Y, Uemura R, Tanaka M, Izawa T, Yamate J, Kuramoto T, Kaneko T, Mashimo T, Yamamoto T, Serikawa T, Kuwamura M.

    Experimental Animals   70 ( 1 )   137 - 143   2021年02月

  • Analyses of hemorrhagic diathesis in high-iron diet-fed rats 査読

    Inai Y, Izawa T, Mori M, Atarashi M, Tsuchiya S, Kuwamura M, Yamate J.

    Journal of Toxicologic Pathology   34 ( 1 )   33 - 41   2021年02月

  • Immunophenotypical characterization of M1/M2 macrophages and lymphocytes in cisplatin-induced rat progressive renal fibrosis 査読

    Nakagawa M, Karim MR, Izawa T, Kuwamura M, Yamate J.

    Cells   10 ( 2 )   2021年01月

  • Characterization of immature myofibroblasts of stellate cell or mesenchymal cell origin in D-galactosamine-induced liver injury in rats 査読

    Rahman N, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

    Veterinary Pathology   58 ( 1 )   80 - 90   2021年01月

  • Parengyodontium album isolated from cutaneous lesions of a pacific white-sided dolphin (Lagenorhynchus obliquidens) during treatment for Paracoccidioidomycosis Ceti 査読

    Kanegae H, Tomino N, Nakamura Y, Minakawa T, Yaguchi T, Izawa T, Sano A, Ueda K.

    Mycopathologia   185 ( 6 )   1021 - 1031   2020年12月

  • Seroprevalence of Antibodies Against Paracoccidioides Spp. in Captive Dolphins from Three Aquaria in Japan 査読

    Minakawa T, Shumoto G, Kezuka C, Izawa T, Sasaki K, Yamaguchi S, Kamezaki N, Yamate J, Konno T, Sano A, Itano EN, Wada S, Willson C, Ueda K.

    Mycopathologia   185 ( 6 )   1013 - 1020   2020年12月

  • Relationship between gut environment, feces-to-food ratio, and androgen deficiency- induced metabolic disorders 査読

    Harada N, Minami Y, Hanada K, Hanaoka R, Kobayashi Y, Izawa T, Sato T, Kato S, Inui H, Yamaji R.

    Gut Microbes   12 ( 1 )   2020年11月

  • Acetaminophen-induced rat hepatotoxicity based on m1/m2-macrophage polarization, in possible relation to damage-associated molecular patterns and autophagy 査読

    Tsuji Y, Kuramochi M, Golbar HM, Izawa T, Kuwamura M, Yamate J.

    International journal of molecular sciences   21 ( 23 )   2020年11月

  • Effects of dexamethasone on hepatic macrophages in normal livers and thioacetamide-induced acute liver lesions in rats 査読

    Hada N, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

    Journal of Toxicologic Pathology   33 ( 4 )   237 - 246   2020年10月

  • Dietary iron overload differentially modulates chemically-induced liver injury in rats 査読

    Mori M, Izawa T, Inai Y, Aikawa R, Fujiwara S, Kuwamura M, Yamate J.

    Nutrients   12 ( 9 )   2020年09月

  • Participation of somatic stem cells, recognized by a unique A3 antibody, in mucosal epithelial regeneration in dextran sulfate sodium (DSS)-induced rat colonic lesions 査読

    Nishina H, Kato-Ichikawa C, Kuramochi, M, Izawa T, Kuwamura M, Yamate J.

    Toxicologic Pathology   48 ( 4 )   560 - 569   2020年06月

  • Hepatocellular necrosis with prominent regenerative reactions in a zonisamide administrated dog. 査読

    Takami Y, Izawa T, Tanaka M, Hatoya S, Nabetani T, Yamate J, Kuwamura M.

    The Journal of veterinary medical science   82 ( 6 )   704 - 706   2020年06月

  • An aortic body carcinoma with sarcomatoid morphology and chondroid metaplasia in a French Bulldog 査読

    Morita C, Tanaka M, Noguchi S, Shimamura S, Wada Y, Izawa T, Yamate J, Kuwamura M.

    The Journal of veterinary medical science   82 ( 5 )   576 - 579   2020年05月

  • Participation of somatic stem cells, labeled by a unique antibody (A3) recognizing both n-glycan and peptide, to hair follicle cycle and cutaneous wound healing in rats 査読

    Katou-Ichikawa C, Nishina H, Tanaka M, Takenaka S, Izawa T, Kuwamura M, Yamate J.

    International journal of molecular sciences   21 ( 11 )   2020年05月

  • Characterization of macrophages and myofibroblasts appearing in dibutyltin dichloride-induced rat pancreatic fibrosis 査読

    Hashimoto A, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J

    Toxicologic Pathology 雑誌   48 ( 3 )   509 - 523   2020年04月

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    共著区分:共著  

  • Carboxyl-, sulfonyl-, and phosphate-terminal dendrimers as a nanoplatform with lymph node targeting 査読

    Nishimoto Y, Nagashima S, Nakajima K, Ohira T, Sato T, Izawa T, Yamate J, Higashikawa K, Kuge Y, Ogawa M, Kojima C.

    International journal of pharmaceutics   576   2020年02月

  • Diffuse leiomyomatosis with circumferential thickening of the gastrointestinal wall, resembling human diffuse leiomyomatosis, in a young miniature dachshund 査読

    Kuramochi M, Izawa T, Mori M, Shimamura S, Shimada T, Kuwamura M, Yamate J.

    The Journal of veterinary medical science   82 ( 2 )   139 - 142   2020年02月

  • Pathological characteristics of Ccdc85c knockout rats: a rat model of genetic hydrocephalus. 査読

    Konishi S, Tanaka N, Mashimo T, Yamamoto T, Sakuma T, Kaneko T, Tanaka M, Izawa T, Yamate J, Kuwamura M.

    Experimental Animals 雑誌   69 ( 1 )   26 - 33   2020年01月

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    共著区分:共著  

  • Hepatic myoepithelial carcinoma in a dog: immunohistochemical comparison with other canine hepatic carcinomas. 査読

    Tsuji Y, Kuramochi M, Izawa T, Akiyoshi H, Yamate J, Kuwamura M.

    Veterinary Pathology 雑誌   56 ( 6 )   889 - 894   2019年11月

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    共著区分:共著  

  • Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell-based immunotherapy 査読

    Wijesekera DP, Yuba E, De Silva NH, Watanabe S-I, Tsukamoto M, Ichida C, Izawa T, Itoh K, Kanegi R, Hatoya S, Yamate J, Inaba T, Sugiura K

    FASEB BioAdvance 雑誌   2 ( 1 )   5 - 17   2019年11月

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    共著区分:共著  

  • Downregulation of aspartoacylase during the progression of myelin breakdown in the dmy mutant rat with mitochondrial magnesium channel MRS2 defect. 査読

    Kuwamura M, Tanimura S, Hasegawa Y, Hoshiai R, Moriyama Y, Tanaka M, Takenaka S, Nagayoshi H, Izawa T, Yamate J, Kuramoto T, Serikawa T.

    Brain Research 雑誌   1718   169 - 175   2019年09月

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    共著区分:共著  

  • Chronic kidney disease following 5/6 nephrectomy disturbs the intestinal microbiota and alters intestinal motility. 査読

    Nishiyama K, Aono K, Fujimoto Y, Kuwamura M, Okada T, Tokumoto H, Izawa T, Okano R, Nakajima H, Takeuchi T, Azuma YT.

    Journal of Cellular Physiology 雑誌   234   6667 - 6678   2019年05月

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    共著区分:共著  

  • Late onset of cerebellar cortical degeneration in a Magellanic penguin (Spheniscus magellanicus). 査読

    Ioannidis M, Tanaka M, Yasui S, Kezuka C, Oyamada M, Hasegawa T, Izawa T, Yamate J, Kuwamura M.

    The Journal of Veterinary Medical Science 雑誌   81   2019年05月

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    共著区分:共著  

  • Spontaneous peripheral neuritis in two electric eels (Electrophorus electricus). 査読

    Rahman N, Kezuka C, Higashiguchi N, Kosaka N, Izawa T, Yamate J, Kuwamura M.

    The Journal of Veterinary Medical Science 雑誌   81   2019年05月

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    共著区分:共著  

  • A case of feline T-cell lymphoma with tropism for striated muscle and peripheral nerve. 査読

    Mori M, Izawa T, Sasaki H, Sonoyama J, Nishimura S, Shimamura S, Shimada T, Hasegawa T, Kuwamura M, Yamate J.

    Journal of Comparative Pathology 雑誌   168   8 - 12   2019年04月

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    共著区分:共著  

    リポジトリURL: http://hdl.handle.net/10466/00017193

  • The localization and distribution of cells labeled by a somatic stem cell-recognizing antibody (A3) in rat colon development; possible presence of a new cell type forming intestinal stem cell niche. 査読

    Nishina H, Katou-Ichikawa C, Kuramochi M, Izawa T, Kuwamura M, Yamate J.

    Journal of Toxicologic Pathology 雑誌   32   37 - 48   2019年01月

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    共著区分:共著  

  • Immunohistochemical characterization of myofibroblasts appearing in isoproterenol-induced rat myocardial fibrosis. 査読

    Koga M, Kuramochi M, Karim MR, Izawa T, Kuwamura M, Yamate J.

    The Journal of Veterinary Medical Science 雑誌   81   127 - 133   2019年01月

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    共著区分:共著  

  • Expression of beta-catenin in regenerating renal tubules of cisplatin-induced kidney failure in rat 査読

    Terada N, Karim MR, Izawa T, Kuwamura M, Yamate J

    Clinical and Experimental Nephrology   22 ( 6 )   1240 - 1250   2018年12月

  • Visualization of specific collagen-producing cells by Col1-GFP transgenic mice revealed novel type I collagen-producing cells other than fibroblasts in systemic organs/tissues 査読

    Yamaguchi T, Kato Y, Okuda T, Rokushima M, Izawa T, Kuwamura M, Yamate J

    Biochemical and Biophysical Research Communications   505 ( 1 )   267 - 273   2018年10月

  • Dietary iron overload abrogates chemically-induced liver cirrhosis in rats 査読

    Atarashi M, Izawa T, Mori M, Inai Y, Kuwamura M, Yamate J

    Nutrients   10 ( 10 )   2018年10月

  • Gene expression profile in retinal excitotoxicity induced by L-glutamate in neonatal rats 査読

    Mitori H, Izawa T, Kuwamura M, Matsumoto M, Yamate J

    Journal of Toxicologic Pathology   31 ( 4 )   301 - 306   2018年10月

  • M1/M2-macrophage polarization-based hepatotoxicity in d-galactosamine-induced acute liver injury in rats 査読

    Rahman N, Pervin M, Kuramochi M, Karim MR, Izawa T, Kuwamura M, Yamate J

    Toxicologic Pathology   46 ( 7 )   764 - 776   2018年10月

  • Comparison of acute gene expression profiles of islet cells obtained via laser capture microdissection between alloxan- and streptozotocin-treated rats 査読

    Kato Y, Masago Y, Kondo C, Yogo E, Torii M, Hishikawa A, Izawa T, Kuwamura M, Yamate J

    Toxicologic Pathology   46 ( 6 )   660 - 670   2018年08月

  • Immunohistochemical analyses of the kinetics and distribution of macrophages in the developing rat kidney 査読

    Matsuyama S, Karim MR, Izawa T, Kuwamura M, Yamate J

    Journal of Toxicologic Pathology   31 ( 3 )   207 - 212   2018年07月

  • Macrophage populations and expression of regulatory inflammatory factors in hepatic macrophage-depleted rat livers under lipopolysaccharide (LPS) treatment 査読

    Pervin M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J

    Toxicologic Pathology   46 ( 5 )   540 - 552   2018年07月

  • The role of interleukin-19 in contact hypersensitivity 査読

    Fujimoto Y, Fujita T, Kuramoto N, Kuwamura M, Izawa T, Nishiyama K, Yoshida N, Nakajima H, Takeuchi T, Azuma YT

    Biological and Pharmaceutical Bulletin   41 ( 2 )   182 - 189   2018年02月

  • Dietary iron supplementation alters hepatic inflammation in a rat model of nonalcoholic steatohepatitis 査読

    Atarashi M, Izawa T, Miyagi R, Ohji S, Hashimoto A, Kuwamura M, Yamate J

    Nutrients   10 ( 2 )   2018年02月

  • Ultrastructural features of canine neuroaxonal dystrophy in a Papillon dog 査読

    Tanaka M, Yamaguchi S, Akiyoshi H, Tsuboi M, Uchida K, Izawa T, Yamate J, Kuwamura M

    The Journal of veterinary medical science   79 ( 12 )   1927 - 1930   2017年12月

  • Participation of tumor-associated myeloid cells in progression of amelanotic melanoma (RMM tumor line) in F344 rats, with particular reference to MHC class II- and CD163-expressing cells 査読

    Bondoc A, Golbar HM, Pervin M, Katou-Ichikawa C, Tanaka M, Izawa T, Kuwamura M, Yamate J

    Cancer Microenvironment   10 ( 1-3 )   9 - 24   2017年12月

  • Immunophenotypical analysis of pancreatic interstitial cells in the developing rat pancreas and myofibroblasts in the fibrotic pancreas in dogs and cats 査読

    Hashimoto A, Karim MR, Izawa T, Kuwamura M, Yamate J

    The Journal of veterinary medical science   79 ( 12 )   1920 - 1926   2017年12月

  • Immunolocalization of beta-catenin, E-cadherin and N-cadherin in neonate and adult rat kidney 査読

    Terada N, Karim MR, Izawa T, Kuwamura M, Yamate J

    The Journal of veterinary medical science   79 ( 11 )   1785 - 1790   2017年11月

  • Development of effective tumor immunotherapy using a novel dendritic cell-targeting Toll-like receptor ligand 査読

    De Silva NH, Akazawa T, Wijewardana V, Inoue N, Oyamada M, Ohta A, Tachibana Y, Wijesekera DPH, Kuwamura M, Nishizawa Y, Itoh K, Izawa T, Hatoya S, Hasegawa T, Yamate J, Inaba T, Sugiura K

    PLoS One   12 ( 11 )   2017年11月

  • Unilateral luteoma of the ovary in a pregnant Risso's dolphin (Grampus griseus) 査読

    Nishina H, Izawa T, Ozaki M, Kuwamura M, Yamate J

    The Journal of veterinary medical science   79 ( 10 )   1749 - 1752   2017年10月

  • Attenuation of thioacetamide-induced hepatocellular injury by short-term repeated injections associated with down-regulation of metabolic enzymes and relationship with MHC class II-presenting cells 査読

    Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, LaMarre J, Yamate J

    Experimental and toxicologic pathology   69 ( 8 )   589 - 597   2017年10月

  • Characterization of pancreatic islet cell tumors and renal tumors induced by a combined treatment of streptozotocin and nicotinamide in male SD rats 査読

    Kato Y, Masuno K, Fujisawa K, Tsuchiya N, Torii M, Hishikawa A, Izawa T, Kuwamura M, Yamate J

    Experimental and toxicologic pathology   69 ( 7 )   397 - 403   2017年09月

  • ヘリコバクター除菌療法後に寛解に至った猫の胃小細胞型B細胞性リンパ腫の1例 査読

    辻 誠, 上本 康喜, 河﨑 哲也, 石塚 泰雄, 井澤 武史

    日本獣医師会雑誌 雑誌   70 ( 8 )   523 - 528   2017年08月

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    共著区分:共著  

  • Cutaneous histiocytic sarcoma with regional lymph node metastasis in a Netherland dwarf rabbit (Oryctolagus cuniculus) 査読

    Karim MR, Izawa T, Pervin M, Sasai H, Kuwamura M, Yamate J

    Journal of Comparative Pathology   156 ( 2-3 )   169 - 172   2017年07月

  • Spontaneous nephroblastoma with striated muscle differentiation in an F344 rat 査読

    Tanaka N, Izawa T, Yamate J, Kuwamura M

    Journal of Toxicologic Pathology   30 ( 3 )   231 - 234   2017年07月

  • Pleomorphic adenoma of the labial gland, characterized by reticular pattern of myoepithelial cells in a dog 査読

    Kuramochi M, Izawa T, Nishimura S, Shimada T, Kuwamura M, Yamate J

    The Journal of veterinary medical science   79 ( 7 )   1163 - 1166   2017年07月

  • Attenuation of alpha-naphthylisothiocyanate (ANIT)-induced biliary fibrosis by depletion of hepatic macrophages in rats 査読

    Golbar HM, Izawa T, Bondoc A, Wijesundera KK, Tennakoon AH, Kuwamura M, Yamate J

    Experimental and toxicologic pathology   69 ( 4 )   221 - 230   2017年04月

  • Expression of Ccdc85C, a causative protein for murine hydrocephalus, in the mammary gland tumors of dogs 査読

    Tanaka N, Izawa T, Takenaka S, Akiyoshi H, Yamate J, Kuwamura M

    Histology and Histopathology   32 ( 4 )   397 - 403   2017年04月

  • Interleukin-19 contributes as a protective factor in experimental Th2-mediated colitis 査読

    Fujimoto Y, Azuma YT, Matsuo Y, Kuwamura M, Kuramoto N, Miki M, Azuma N, Teramoto M, Nishiyama K, Izawa T, Nakajima H, Takeuchi T

    Naunyn-Schmiedeberg's Archives of Pharmacology   390 ( 3 )   261 - 268   2017年03月

  • Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death 査読

    Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, Azuma YT, Kuwamura M, Yamaji R, Takeuchi T

    The Journal of Biological Chemistry   292 ( 11 )   4727 - 4742   2017年03月

  • Enhanced expression of Trib3 during the development of myelin breakdown in dmy myelin mutant rats 査読

    Shimotsuma Y, Tanaka M, Izawa T, Yamate J, Kuwamura M

    PLoS One   11 ( 12 )   2016年12月

  • Developing Stage-dependent Retinal Toxicity Induced by l-glutamate in Neonatal Rats 査読

    Mitori H, Izawa T, Kuwamura M, Matsumoto M, Yamate J

    Toxicologic Pathology   44 ( 8 )   1137 - 1145   2016年12月

  • Hypogonadism alters cecal and fecal microbiota in male mice 査読

    Harada N, Hanaoka R, Hanada K, Izawa T, Inui H, Yamaji R

    Gut Microbes   7 ( 6 )   533 - 539   2016年11月

  • Establishment and characterization of a transplantable tumor line (RMM) and cell line (RMM-C) from a malignant amelanotic melanoma in the F344 rat, with particular reference to galectin-3 expression in vivo and in vitro 査読

    Bondoc A, Katou-Ichikawa C, Golbar HM, Tanaka M, Izawa T, Kuwamura M, Yamate J

    Histology and Histopathology   31 ( 11 )   1195 - 1207   2016年11月

  • Alteration of microRNA expressions in the pons and medulla in rats after 3,3'-iminodipropionitrile administration 査読

    Ogata K, Kushida M, Miyata K, Sumida K, Takeda S, Izawa T, Kuwamura M, Yamate J

    Journal of Toxicologic Pathology 雑誌   29 ( 4 )   229 - 236   2016年10月

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    共著区分:共著  

  • The kinetics of damage-associated molecular patterns (DAMPs) and toll-like receptors during thioacetamide-induced acute liver injury in rats 査読

    Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, Yamate J

    Experimental and toxicologic pathology   68 ( 8 )   471 - 477   2016年09月

  • Metastatic Liposarcoma in a South African Fur Seal (Arctocephalus pusillus) 査読

    Pervin M, Izawa T, Ito S, Kuwamura M, Yamate J

    Journal of Comparative Pathology   155 ( 1 )   72 - 75   2016年08月

  • M1-/M2-macrophage polarization in pseudolobules consisting of adipohilin-rich hepatocytes in thioacetamide (TAA)-induced rat hepatic cirrhosis. 査読

    Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J

    Experimental and Molecular Pathology   101 ( 1 )   133 - 142   2016年08月

  • Detection of multiple budding yeast cells and a partial sequence of 43-kda glycoprotein coding gene of paracoccidioides brasiliensis from a case of lacaziosis in a female pacific white-sided dolphin (Lagenorhynchus obliquidens) 査読

    Minakawa T, Ueda K, Tanaka M, Tanaka N, Kuwamura M, Izawa T, Konno T, Yamate J, Itano EN, Sano A, Wada S

    Mycopathologia   181 ( 7-8 )   523 - 529   2016年08月

  • Multiple histiocytic foam cell nodules in the tongue of miniature dachshund dogs 査読

    Katou-Ichikawa C, Izawa T, Sasai H, Kuwamura M, Yamate J

    Veterinary Pathology   53 ( 3 )   625 - 628   2016年05月

  • Transient effects of empty liposomes on hepatic macrophage populations in rats 査読

    Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J

    Journal of Toxicologic Pathology   29 ( 2 )   139 - 144   2016年04月

  • Depletion of hepatic macrophages aggravates liver lesions induced in rats by thioacetamide (TAA) 査読

    Golbar HM, Izawa T, Wijesundera KK, Bondoc A, Tennakoon AH, Kuwamura M, Yamate J

    Toxicologic Pathology   44 ( 2 )   246 - 258   2016年02月

  • Immunophenotypical characterization and influence on liver homeostasis of depleting and repopulating hepatic macrophages in rats injected with clodronate 査読

    Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J

    Experimental and toxicologic pathology   68 ( 2-3 )   113 - 124   2016年02月

  • Rat malignant fibrous histiocytoma (MFH)-derived cloned cell lines (MT-8 and MT-9) show different differentiation in mesenchymal stem cell lineage 査読

    Kotera T, Katou-Ichikawa C, Tennakoon AH, Tanaka M, Tanaka N, Izawa T, Kuwamura M, Yamate J

    Experimental and toxicologic pathology   67 ( 10 )   499 - 507   2015年10月

  • pH-sensitive polymer-liposome-based antigen delivery systems potentiated with interferon-gamma gene lipoplex for efficient cancer immunotherapy 査読

    Yuba E, Kanda Y, Yoshizaki Y, Teranishi R, Harada A, Sugiura K, Izawa T, Yamate J, Sakaguchi N, Koiwai K, Kono K

    Biomaterials   67   214 - 224   2015年10月

  • M1-/M2-macrophages contribute to the development of GST-P-positive preneoplastic lesions in chemically-induced rat cirrhosis 査読

    Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J

    Experimental and toxicologic pathology   67 ( 9 )   467 - 475   2015年09月

  • Anti-fibrotic role of miR-214 in thioacetamide-induced liver cirrhosis in rats 査読

    Izawa T, Horiuchi T, Atarashi M, Kuwamura M, Yamate J

    Toxicologic Pathology   43 ( 6 )   844 - 851   2015年08月

  • Ccdc85C, a causative protein for hydrocephalus and subcortical heterotopia, is expressed in the systemic epithelia with proliferative activity in rats 査読

    Tanaka N, Izawa T, Takenaka S, Yamate J, Kuwamura M.

    Histology and Histopathology   30 ( 7 )   823 - 832   2015年07月

  • Chordoma of the thoracic vertebrae in a Bengal tiger (Panthera tigris tigris) 査読

    Kuramochi M, Izawa T, Hori M, Kusuda K, Shimizu J, Iseri T, Akiyoshi H, Ohashi F, Kuwamura M, Yamate J

    The Journal of veterinary medical science   77 ( 7 )   893 - 895   2015年07月

  • Computed tomography and magnetic resonance imaging of thoracic chordoma in a Bengal tiger (Panthera tigris tigris). 査読

    Iseri T, Shimizu J, Akiyoshi H, Kusuda K, Hayashi A, Mie K, Izawa T, Kuwamura M, Yamate J, Fujimoto Y, Ohashi F

    The Journal of veterinary medical science   77 ( 7 )   857 - 860   2015年07月

  • Analysis of glial fibrillary acidic protein (GFAP)-expressing ductular cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA) 査読

    Tennakoon AH, Izawa T, Wijesundera KK, Katou-Ichikawa C, Tanaka M, Golbar HM, Kuwamura M, Yamate J.

    Experimental and Molecular Pathology   98 ( 3 )   476 - 485   2015年06月

  • Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic beta-cells 査読

    Harada N, Katsuki T, Takahashi Y, Masuda T, Yoshinaga M, Adachi T, Izawa T, Kuwamura M, Nakano Y, Yamaji R, Inui H.

    Journal of Cell Biology   116 ( 6 )   998 - 1006   2015年06月

  • Participation of bone morphogenetic protein (BMP)-6 and osteopontin in cisplatin (CDDP)-induced rat renal fibrosis 査読

    Yano R, Golbar HM, Izawa T, Sawamoto O, Kuwamura M, Yamate J.

    Experimental and toxicologic pathology   67 ( 2 )   99 - 107   2015年02月

  • Immunohistochemical characterization of glial fibrillary acidic protein (GFAP)-expressing cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA) 査読

    Tennakoon AH, Izawa T, Wijesundera KK, Murakami H, Katou-Ichikawa C, Tanaka M, Golbar HM, Kuwamura M, Yamate J.

    Experimental and toxicologic pathology   67 ( 1 )   53 - 63   2015年01月

  • Amphotericin B induces glial cell line-derived neurotrophic factor in rat brain. 査読

    Motoyoshi-Yamashiro A, Takano K, Kawabe K, Izawa T, Nakajima H, Nakamura Y.

    The Journal of veterinary medical science   76 ( 10 )   2014年10月

  • Characterization of rat testicular teratoma and its derived cell lines, with particular reference to possible mesenchymal differentiations. 査読

    Yamate, J. Gamou, K. Izawa-Ogata, K. Kotera, T. Izawa, T. Takenaka, S. Sawamoto, O. Kuwamura, M.

    Histology and Histopathology   29 ( 9 )   1201 - 1216   2014年09月

  • Involvement of neutrophil gelatinase-associated lipocalin and osteopontin in renal tubular regeneration and interstitial fibrosis after cisplatin-induced renal failure. 査読

    Kashiwagi E, Tonomura Y, Kondo C, Masuno K, Fujisawa K, Tsuchiya N, Matsushima S, Torii M, Takasu N, Izawa T, Kuwamura M, Yamate J.

    Experimental and toxicologic pathology   66 ( 7 )   301 - 311   2014年09月

  • The VF rat with abnormal myelinogenesis has a mutation in Dopey1. 査読

    Tanaka, M. Izawa, T. Yamate, J. Franklin, R. J. Kuramoto, T. Serikawa, T. Kuwamura, M.

    Glia   62 ( 9 )   1530 - 1542   2014年09月

  • Myoepithelioma of the gland of the third eyelid in a dog. 査読

    Bondoc, A. Izawa, T. Hirata, S. Hasegawa, T. Kuwamura, M. Golbar, H. M. Yamate, J.

    Journal of Comparative Pathology   151 ( 2-3 )   186 - 189   2014年08月

  • Expression of nestin in remodelling of alpha-naphthylisothiocyanate-induced acute bile duct injury in rats 査読

    Golbar HM, Izawa T, Wijesundera KK, Tennakoon AH, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J

    Journal of Comparative Pathology   151 ( 2-3 )   255 - 263   2014年08月

  • A collision tumour consisting of malignant trichoblastoma and melanosarcoma in a rabbit. 査読

    Golbar HM, Izawa T, Kuwamura M, Fujita D, Sasai H, Yamate J.

    Journal of Comparative Pathology   151 ( 1 )   63 - 66   2014年07月

  • Calponin expression in renal tubulointerstitial fibrosis induced in rats by Cisplatin. 査読

    Yuasa T, Yano R, Izawa T, Kuwamura M, Yamate J.

    Journal of Toxicologic Pathology   27 ( 1 )   97 - 103   2014年04月

  • The first case of infectious spleen and kidney necrosis virus (ISKNV) infection in aquarium-maintained mandarin fish, Siniperca chuatsi (Basilewsky), in Japan. 査読

    Tanaka N, Izawa T, Kuwamura M, Higashiguchi N, Kezuka C, Kurata O, Wada S, Yamate J.

    Journal of Fish Diseases   37 ( 4 )   401 - 405   2014年04月

  • Phaeochromocytoma and hepatocellular carcinoma with nuclear glycogenation of the hepatocytes in a predatory carp, Chanodichthys erythropterus (Basilewsky). 査読

    Tanaka N, Izawa T, Kuwamura M, Higashiguchi N, Kezuka C, Yamate J.

    Journal of Fish Diseases   37 ( 4 )   411 - 414   2014年04月

  • M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology. 査読

    Wijesundera KK, Izawa T, Murakami H, Tennakoon AH, Golbar HM, Kato-Ichikawa C, Tanaka M, Kuwamura M, Yamate J.

    Histology and Histopathology   29 ( 4 )   497 - 511   2014年04月

  • M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-3. 査読

    Wijesundera KK, Izawa T, Tennakoon AH, Murakami H, Golbar HM, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J.

    Experimental and Molecular Pathology   96 ( 3 )   382 - 392   2014年04月

  • Evaluation of Serum Phosphorylated Neurofilament Subunit NF-H as a Prognostic Biomarker in Dogs With Thoracolumbar Intervertebral Disc Herniation. 査読

    Nishida H, Nakayama M, Tanaka H, Kamishina H, Izawa T, Hatoya S, Sugiura K, Suzuki Y, Ide C, Inaba T.

    Veterinary Surgery   43 ( 3 )   289 - 293   2014年03月

  • Inflammatory regulation of iron metabolism during thioacetamide-induced acute liver injury in rats. 査読

    Izawa T, Murakami H, Wijesundera KK, Golbar HM, Kuwamura M, Yamate J.

    Experimental and toxicologic pathology   66 ( 41673 )   155 - 162   2014年03月

  • A case of meconium aspiration syndrome in a bottlenose dolphin (Tursiops truncatus) calf. 査読

    Tanaka M, Izawa T, Kuwamura M, Ozaki M, Nakao T, Ito S, Yamate J.

    The Journal of veterinary medical science   76 ( 1 )   81 - 84   2014年02月

  • Primary cerebral T-cell lymphoma in a sea otter (enhydra lutris). 査読

    Tanaka N, Izawa T, Kashiwagi-Yamamoto E, Kuwamura M, Ozaki M, Nakao T, Yamate J.

    The Journal of veterinary medical science   75 ( 12 )   1667 - 1669   2013年12月

  • Combined hepatocellular-cholangiocarcinoma in a yellow-headed amazon (Amazona oratrix) 査読

    Tennakoon, A. H. Izawa, T. Fujita, D. Denda, Y. Seto, E. Sasai, H. Kuwamura, M. Yamate, J.

    The Journal of veterinary medical science   75 ( 11 )   1507 - 1510   2013年11月

  • Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury 査読

    Tennakoon, A. H. Izawa, T. Wijesundera, K. K. Golbar, H. M. Tanaka, M. Ichikawa, C. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   65 ( 41828 )   1159 - 1171   2013年11月

  • Spontaneous extraskeletal osteosarcoma in a rabbit (Oryctolagus cuniculus): histopathological and immunohistochemical findings. 査読

    Wijesundera, K. K. Izawa, T. Fujita, D. Denda, Y. Seto, E. Sasai, H. Kuwamura, M. Yamate, J.

    Journal of Toxicologic Pathology   26 ( 3 )   309 - 312   2013年09月

  • Slowly progressive cholangiofibrosis induced in rats by alpha-naphthylisothiocyanate (ANIT), with particular references to characteristics of macrophages and myofibroblasts 査読

    Golbar, H. M. Izawa, T. Ichikawa, C. Tanaka, M. Juniantito, V. Sawamoto, O. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   65 ( 6 )   825 - 835   2013年09月

  • Expressions of Iba1 and galectin-3 (Gal-3) in thioacetamide (TAA)-induced acute rat liver lesions 査読

    Wijesundera, K. K. Juniantito, V. Golbar, H. M. Fujisawa, K. Tanaka, M. Ichikawa, C. Izawa, T. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   65 ( 6 )   799 - 808   2013年09月

  • Two cases of lacaziosis in bottlenose dolphins (Tursiops truncates) in Japan. 査読

    Ueda, K. Sano, A. Yamate, J. Itano, E. Kuwamura, M. Izawa, T. Tanaka, M. Hasegawa, Y. Chibana, H. Izumisawa, Y. Miyahara, H. Uchida, S.

    Case Reports in Veterinary Medicine   2013年09月

  • 内側腸骨リンパ節に転移した犬の精上皮腫に対し 術前放射線治療及び外科的切除を実施した 1 例 査読

    山本亮平, 秋吉秀保, 福井仁美, 平田翔吾, 井澤武史, 大橋文人, 久保喜平

    日本獣医師会雑誌 雑誌   66   553 - 556   2013年08月

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  • Thy-1 expression, a possible marker of early myofibroblast development, in renal tubulointerstitial fibrosis induced in rats by cisplatin 査読

    Yuasa, T. Juniantito, V. Ichikawa, C. Yano, R. Izawa, T. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   65 ( 5 )   651 - 659   2013年07月

  • Expression patterns of heat shock protein 25 in carbon tetrachloride-induced rat liver injury 査読

    Fujisawa, K. Yabuuchi, C. Izawa, T. Kuwamura, M. Takasu, N. Torii, M. Yamate, J.

    Experimental and toxicologic pathology   65 ( 5 )   469 - 76   2013年07月

  • Immunohistochemical characterization of macrophages and myofibroblasts in fibrotic liver lesions due to fasciola infection in cattle 査読

    Golbar, H. M. Izawa, T. Juniantito, V. Ichikawa, C. Tanaka, M. Kuwamura, M. Yamate, J.

    The Journal of veterinary medical science   75 ( 7 )   857 - 865   2013年07月

  • Immunophenotypical analysis of myofibroblasts and mesenchymal cells in the bleomycin-induced rat scleroderma, with particular reference to their origin 査読

    Juniantito, V. Izawa, T. Yuasa, T. Ichikawa, C. Tanaka, M. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   65 ( 5 )   567 - 577   2013年07月

  • Generation of functional platelets from canine induced pluripotent stem cells 査読

    Nishimura, T. Hatoya, S. Kanegi, R. Sugiura, K. Wijewardana, V. Kuwamura, M. Tanaka, M. Yamate, J. Izawa, T. Takahashi, M. Kawate, N. Tamada, H. Imai, H. Inaba, T.

    Stem Cells and Development   22 ( 14 )   2026 - 2035   2013年07月

  • Distribution of cells labelled by a novel somatic stem cell-recognizing antibody (A3) in pulmonary genesis and bleomycin induced pulmonary fibrosis in rats 査読

    Hori, M. Juniantito, V. Izawa, T. Ichikawa, C. Tanaka, M. Tanaka, K. Takenaka, S. Kuwamura, M. Yamate, J.

    Journal of Comparative Pathology   148 ( 4 )   385 - 395   2013年05月

  • Pulmonary dystrophic oxalosis and its possible relation to fibrosis in an aged gentoo penguin (Pygoscelis papua) 査読

    Wijesundera, K.K. Izawa, T. Tanaka, M. Nakao, T. Maezono, Y. Ito, S. Kuwamura, M. Yamate, J.

    The Journal of veterinary medical science   75 ( 3 )   365 - 368   2013年04月

  • Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis 査読

    Uehara, T. Ainslie, G.R. Kutanzi, K. Pogribny, I.P. Muskhelishvili, L. Izawa, T. Yamate, J. Kosyk, O. Shymonyak, S. Bradford, B.U. Boorman, G.A. Bataller, R. Rusyn, I.

    Toxicological sciences   132 ( 1 )   53 - 63   2013年03月

  • Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: 査読

    Ichikawa, C. Izawa, T. Juniantito, V. Tanaka, M. Hori, M. Tanaka, K. Takenaka, S. Kuwamura, M. Yamate, J.

    Histology and Histopathology   28 ( 2 )   257 - 268   2013年02月

  • Immunophenotypical characterization of macrophages in rat bleomycin-induced scleroderma 査読

    Juniantito, V. Izawa, T. Yuasa, T. Ichikawa, C. Yano, R. Kuwamura, M. Yamate, J.

    Veterinary Pathology   50 ( 1 )   76 - 85   2013年01月

  • Abnormal myelinogenesis in the central nervous system of the VF mutant rat with recoverable tremor 査読

    Tanaka, M. Soma, K. Izawa, T. Yamate, J. Franklin, R.J. Kuramoto, T. Serikawa, T. Kuwamura. M.

    Brain Research   1488   104 - 112   2012年12月

  • Incidental synovial myxoma with extensive intermuscular infiltration in a dog 査読

    Izawa, T. Tanaka, M. Aoki, M. Ohashi, F. Yamate, J. Kuwamura, M.

    The Journal of veterinary medical science   74 ( 12 )   1631 - 1633   2012年12月

  • Amelioration of cisplatin-induced rat renal lesions by a cyclooxygenase (COX)-2 selective inhibitor 査読

    Yamamato, E. Izawa, T. Sawamoto, O. Juniantito, V. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   64 ( 6 )   625 - 631   2012年09月

  • Deep granulomatous dermatitis of the fin caused by Fusarium solani in a false killer whale (Pseudorca crassidens) 査読

    Tanaka, M. Izawa, T. Kuwamura, M. Nakao, T. Maezono, Y. Ito, S. Murata, M. Murakami, M. Sano, A. Yamate, J.

    The Journal of veterinary medical science   74 ( 6 )   779 - 782   2012年07月

  • Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts 査読

    Juniantito, V. Izawa, T. Yuasa, T. Ichikawa, C. Yamamoto, E. Kuwamura, M. Yamate, J.

    Histology and Histopathology   27 ( 4 )   515 - 527   2012年04月

  • A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain 査読

    Nakajima, H. Kubo, T. Semi, Y. Itakura, M. Kuwamura, M. Izawa, T. Azuma, Y.T. Takeuchi, T.

    Journal of Biotechnology   157 ( 2 )   326 - 333   2012年01月

  • Immunohistochemical analyses of the kinetics and distribution of macrophages, hepatic stellate cells and bile duct epithelia in the developing rat live 査読

    Golbar, H. M. Izawa, T. Murai, F. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   64 ( 41641 )   2012年01月

  • Immunohistochemical expressions of main PGE2 biosynthesis-related enzymes and PGE2 receptor in rat nephrogenesis 査読

    Yamamoto, E. Izawa, T. Kuwamura, M. Yamate, J.

    Journal of Toxicologic Pathology   24 ( 4 )   257 - 261   2011年12月

  • A collision tumor consisting of granular cell tumor and adenocarcinoma in the uterus of an aged djungarian hamster 査読

    Golbar, H.M. Izawa, T. Kuwamura,M. Okamura, K. Fujita, D. Tagami, Y. Sasai, H. Yamate, J.

    Journal of Toxicologic Pathology   24 ( 4 )   233 - 237   2011年12月

  • Heterogeneity of macrophage populations and expression of galectin-3 in cutaneous wound healing in rats 査読

    Juniantito, V. Izawa, T. Yamamato, E. Murai, F. Kuwamura, M. Yamate, J.

    Journal of Comparative Pathology   145 ( 4 )   378 - 389   2011年11月

  • A rhabdomyosarcoma arising in the larynx of a dog 査読

    Yamate, J. Murai, F. Izawa, T. Akiyoshi, H. Shimizu, J. Ohashi, F. Kuwamura, M.

    Journal of Toxicologic Pathology   24 ( 3 )   179 - 182   2011年09月

  • Relationship of heat shock protein 25 with reactive macrophages in thioacetamide-induced rat liver injury 査読

    Fujisawa, K. Miyoshi, T. Tonomura, Y. Izawa, T. Kuwamura, M. Torii, M. Yamate, J.

    Experimental and toxicologic pathology   63 ( 6 )   599 - 605   2011年09月

  • Cardiac hamartoma in a young squirrel monkey who died suddenly 査読

    Golbar, H. M. Izawa, T. Kuwamura, M. Fujita, D. Okamura, K. Yamazaki, R. Tagami, Y. Sasai, H. Yamate, J.

    Veterinary Pathology   48 ( 5 )   970 - 974   2011年09月

  • Immunohistochemical characterization of macrophages and myofibroblasts in α-aphthylisothiocyanate (ANIT)-induced bile duct injury and subsequent fibrogenesis in rats 査読

    Glober, H.M. Izawa, T. Yano, R. Ichikawa, C. Sawamoto, O. Kuwamura, M. LaMarre, J. Yamate, J.

    Toxicologic Pathology   39 ( 5 )   795 - 808   2011年08月

  • Oligodendroglial pathology in the development of myelin breakdown in the dmy mutant rat 査読

    Kuwamura, M. Inumaki, K. Tanaka, M. Shirai, M. Izawa, T. Yamate, J. Franklin, R. J. Kuramoto, T. Serikawa, T.

    Brain Research   1389   161 - 168   2011年05月

  • Encapsulating peritoneal sclerosis associated with abnormal liver development in a young dog 査読

    Izawa, T. Murai, F. Akiyoshi, H. Ohashi, F. Yamate, J. Kuwamura, M.

    The Journal of veterinary medical science   73 ( 5 )   697 - 700   2011年05月

  • Comparative gene expression analysis in the skeletal muscles of dysferlin-deficient SJL/J and A/J mice. 査読

    Kobayashi, K. Izawa, T. Kuwamura, M. Yamate, J.

    Journal of Toxicologic Pathology   24   49 - 62   2011年04月

  • A mutation in the gene encoding mitochondrial Mg(2)+ channel MRS2 results in demyelination in the rat 査読

    Kuramoto, T. Kuwamura, M. Tokuda, S. Izawa, T. Nakane, Y. Kitada, K. Akao, M. Guenet, J. L. Serikawa, T.

    PLoS genetics   7 ( 1 )   2011年01月

  • Relationship of cell proliferating marker expressions with PGE2 receptors in regenerating rat renal tubules after cisplatin injection 査読

    Yamamoto, E. Izawa, T. Juniantito, V. Kuwamura, M. Yamate, J.

    Journal of Toxicologic Pathology   23 ( 4 )   271 - 275   2011年01月

  • A mutation in the gene encoding mitochondria Mg2+ channel MRS2 results in demyelination in the rat 査読

    Kuramoto T, Kuwamura M, Tokuda S, Izawa T, Nakane Y, Kitada K, Akao M, Guenet JL, Serikawa T

    PLoS Genetics 雑誌   7 ( 1 )   2011年01月

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  • Relationship of Cell Proliferating Marker Expressions with PGE(2) Receptors in Regenerating Rat Renal Tubules after Cisplatin Injection 査読

    Yamamoto E, Izawa T, Juniantito V, Kuwamura M, Yamate J.

    Journal of Toxicologic Pathology 雑誌   23 ( 4 )   271 - 275   2010年12月

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  • The distribution and characterization of skeletal muscle lesions in dysferlin-deficient SJL and A/J mice 査読

    Kobayashi, K. Izawa, T. Kuwamura, M. Yamate, J.

    Experimental and toxicologic pathology   62 ( 5 )   509 - 517   2010年09月

  • Involvement of endogenous prostaglandin E2 in tubular epithelial regeneration through inhibition of apoptosis and epithelial-mesenchymal transition in cisplatin-induced rat renal lesions 査読

    Yamamoto, E. Izawa, T. Juniantito, V. Kuwamura, M. Sugiura, K. Takeuchi, T. Yamate, J.

    Histology and Histopathology   25 ( 8 )   995 - 1007   2010年08月

  • Abnormal iron accumulation is involved in the pathogenesis of the demyelinating dmy rat but not in the hypomyelinating mv rat 査読

    Izawa, T. Yamate, J. Franklin, R. J. Kuwamura, M.

    Brain Research   1349   105 - 114   2010年08月

  • The kinetics and distribution of different macrophage populations in the developing rat skin 査読

    Juniantito, V. Izawa, T. Yamamoto, E. Kuwamura, M. Yamate, J.

    Histology and Histopathology   25 ( 8 )   985 - 94   2010年08月

  • Thy-1 expressing mesenchymal cells in rat nephrogenesis, in correlation with cells immunoreactive for a-smooth muscle actin and vimentin 査読

    Yuasa, T. Izawa, T. Kuwamura, M. Yamate, J.

    Journal of Toxicologic Pathology   23 ( 1 )   2010年04月

  • Abnormal myelinogenesis both in the white and gray matter of the attractin-deficient mv rat 査読

    Izawa, T. Yamate, J. Franklin, R. J. Kuwamura, M.

    Brain Research   1312   145 - 155   2010年02月

  • Uterine adenocarcinoma with prominent desmoplasia in a geriatric miniature pig 査読

    Golbar, H. Izawa, T. Kuwamura, M. Ito, S. Yamate, J.

    The Journal of veterinary medical science   72 ( 2 )   253 - 256   2010年02月

  • Gastrointestinal candidiasis in an Aldabra giant tortoise (Geochelone gigantea) 査読

    Juniantito, V. Izawa, T. Kuwamura, M. Yonezawa, M. Ito, S. Yamate, J.

    The Journal of veterinary medical science   71 ( 9 )   1269 - 1272   2009年09月

  • Participation of functionally different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury 査読

    Mori, Y. Izawa, T. Takenaka, S. Kuwamura, M. Yamate, J.

    Toxicologic Pathology   37 ( 4 )   463 - 473   2009年06月

  • Vasoformative disorder, resembling littoral cell angioma, of the spleen in a geriatric Japanese macaque (Macaca fuscata) 査読

    Yamate, J. Izawa, T. Kuwamura, M. Mitsunaga, F. Nakamura, S.

    Veterinary Pathology   46 ( 3 )   520 - 525   2009年05月

  • Malignant seminoma with multiple visceral metastases in a guinea fowl (Numida meleagris) kept in a zoo 査読

    Golbar, H. M. Izawa, T. Kuwamura, M. Yonezawa, M. Ito, S. Yamate, J.

    Avian Diseases   53 ( 1 )   143 - 145   2009年05月

  • Macrophage populations and expressions of regulatory proinflammatory factors in the rat meninx under lipopolysaccharide treatment in vivo and in vitro 査読

    Yamate, J. Ishimine, S. Izawa, T. Kumagai, D. Kuwamura, M.

    Histology and Histopathology   24 ( 1 )   13 - 24   2009年01月

  • Cutaneous rhabdoid tumor in a cat 査読

    Izawa, T. Yamate, J. Takeda, S. Kumagai, D. Kuwamura, M.

    Veterinary Pathology   45 ( 6 )   897 - 900   2008年11月

  • Cellular responses in the spinal cord during development of hypomyelination in the mv rat 査読

    Izawa, T. Takenaka, S. Ihara, H. Kotani, T. Yamate, J. Franklin, R. J. Kuwamura, M.

    Brain Research   1195   120 - 129   2008年02月

  • Olfactory neuroblastoma in a horse 査読

    Yamate, J. Izawa, T. Ogata, K. Kobayashi, O. Okajima, R. Kuwamura, M. Kotani, T. Aoki, M.

    The Journal of veterinary medical science   68 ( 5 )   495 - 498   2006年05月

▼全件表示

書籍等出版物

  • 動物病理学各論 第3版

    中山 裕之 他( 担当: 共著)

    日本獣医病理学専門家協会(JCVP)  2021年03月 

  • 動物病理カラーアトラス 第2版

    中山 裕之 他( 担当: 共著)

    文永堂出版(日本獣医病理学専門家協会編)  2018年01月 

MISC(その他記事)

  • 非アルコール性脂肪性肝炎(NASH)の 病態進展に関わる鉄過剰の役割 査読

    新 真智,井澤 武史,桑村 充,山手 丈至

    日本薬理学雑誌   154   2019年08月

     詳細を見る

  • Histopathological analysis of rat hepatotoxicity based on macrophage functions: in particular, an analysis for thioacetamide-induced hepatic lesions 査読

    Yamate J, Izawa T, Kuwamura M

    Food Safety   3   61 - 73   2016年09月

     詳細を見る

  • Pathogenesis of the type 2 of epithelial to mesenchymal transition (EMT) in renal and hepatic fibrosis 査読

    Tennakoon AH, Izawa T, Kuwamura M, Yamate J

    Journal of Clinical Medicine   5 ( 1 )   2016年01月

     詳細を見る

  • Dysferlin and animal models for dysferlinopathy 査読

    Kobayashi K, Izawa T, Kuwamura M, Yamate J

    Journal of Toxicologic Pathology   25 ( 2 )   135 - 147   2012年06月

     詳細を見る

産学官連携可能研究(シーズ)キーワード

  • 病理標本作製(Preparation for histopathological specimen),病理組織評価(Histopathological evaluation),免疫組織化学(Immunohistochemistry/multi-color immunofluorescence),In situ hybridization,Laser microdissection

科研費

  • 鉄過剰による新規肝保護機構の解明

    2020年

担当授業科目

  • 生物学A

    2021年度    

  • 統合生体学特別講義B

    2021年度    

  • 毒性病理学実習

    2021年度   実習  

  • 毒性病理学

    2021年度    

  • 疾患モデル動物学

    2021年度    

  • 生物学実験

    2021年度   実習  

  • 獣医病理学A

    2021年度    

  • 獣医病理学B

    2021年度    

  • 獣医病理診断学実習

    2021年度   実習  

  • 臨床基礎実習

    2021年度   実習  

  • 獣医病理組織学実習

    2021年度   実習  

▼全件表示

社会貢献活動

  • 獣医病理学研修セミナー「りんくうゼミ」の主催

    2010年07月 - 継続中

     詳細を見る

    伴侶動物,動物園動物,実験動物の自然発生病変について,基本的な病理組織所見や診断プロセスを重点的に議論し,学習する。セミナーは年3回実施している。