Updated on 2023/04/04

写真a

 
XU YAN
 
Organization
Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology Associate Professor
School of Engineering Department of Chemical Engineering
Title
Associate Professor
Affiliation
Institute of Engineering

Position

  • Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology 

    Associate Professor  2022.04 - Now

  • School of Engineering Department of Chemical Engineering 

    Associate Professor  2022.04 - Now

Degree

  • Bachelor (Engineering) ( Others ) (   Dalian University of Technology (China) )

  • Master (Engineering) ( Others ) (   Dalian Institute of Chemical Physics, Chinese Academy of Sciences (China) )

  • PhD ( The University of Tokyo )

Research Areas

  • Nanotechnology/Materials / Nanobioscience  / Single-Molecule Science, Single-Cell Omics, Single-Molecule Manipulation, Single-Molecule Imaging, Nano Measurement, Nano Synthesis, Nanomedicine, NanoBio Interfaces, Single-Molecule Array

  • Nanotechnology/Materials / Analytical chemistry  / MicroTAS, Single-Molecule Analysuis, Single-Cell Omics,

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Chemical reaction and process system engineering  / Nano Chemical Systems

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Transport phenomena and unit operations  / Single-Molecule Regulated Chemistry

  • Life Science / Biomaterials  / Biomaterials, NanoBio Interfaces, Nanomedicine

  • Life Science / Biomedical engineering  / Biomaterials, NanoBio Interfaces, Nanomedicine

  • Nanotechnology/Materials / Nano/micro-systems  / Nanofluidics, Nano Chemical Systems, Microfluidics, NanoBio Interfaces, Biomaterials, Analytical Chemistry, Nanomedicine, Single Molecule Chemistry, Single-Cell Omics, Nano Energy

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Chemical reaction and process system engineering  / Nano Chemical Processes, New Reactors, Reaction Mechanism, Process Control

  • Nanotechnology/Materials / Analytical chemistry  / Advanced Measurement, New Analytical Methods, MicroTAS

  • Nanotechnology/Materials / Nano/micro-systems  / Nano/Micro Chemical Systems, Nano/Micro Fabrication, Nano/Micro Optical Devices

  • Nanotechnology/Materials / Nanobioscience  / Molecule Manipulation, Nanomeasurement, Single-Molecule Sciences, Nanobio Interfaces, Biomolecular Arrays

  • Life Science / Biomaterials  / Biocompatible Materials, Nanobiomaterials

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Research Interests

  • Single-Molecule Regulated Chemistry (SMRC)

  • Single molecule manipulation

  • Single molecule

  • Nano-in-Nano Integration

  • microTAS

  • Lab on a Chip

  • Single cell

  • Optical Manipulation

  • Optical forces

  • Microfluidics

  • Nanoparticles

  • Nanochannels

  • Nanofluidics

  • Digital Nanochannels (DN)

  • Exosomes

Research subject summary

  • ナノ物質操作

  • 1細胞オミクス

  • 1分子制御化学

  • ナノ化学システム工学

  • ナノ流体工学

Research Career

  • Research in our group is directed toward the integration of "Nano", "Bio", and "Chem" at femtoliter, attoliter, and single molecule scales through nanofluidics. We continue to involve the study and development of novel nanofluidic methods and devices for single cell omics, single molecule chemistry, biomaterials, nanomedicine, energy, and process engineering.

    Individual

    2011.07 - Now 

Professional Memberships

  • THE JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY

  • THE JAPANESE SOCIETY FOR BIOMATERIALS

  • THE MATERIALS RESEARCH SOCIETY OF JAPAN

  • THE SOCIETY FOR CHEMISTRY AND MICRO-NANO SYSTEMS

Awards

  • "Young Innovator Award" of the JST CREST filed of Extracellular Fine Particles

    2022.04   JST  

  • The Academic Award of Gratuate School of Engineering

    2021.11   Osaka Prefecture University  

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    Country:Japan

  • The Academic Award of Gratuate School of Engineering

    2021.11   Osaka Prefecture University  

  • The Academic Award of Gratuate School of Engineering

    2021.06   Osaka Prefecture University  

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    Country:Japan

  • The Academic Award of Gratuate School of Engineering

    2021.06   Osaka Prefecture University  

  • The Academic Award of Gratuate School of Engineering

    2018.10   Osaka Prefecture University  

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    Country:Japan

  • The University President's Award 2015

    2015.08   Osaka Prefecture University  

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    Country:Japan

  • The University President's Award 2014

    2014.08   Osaka Prefecture University  

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    Country:Japan

  • 平成25年度化学とマイクロ・ナノシステム学会若手優秀賞

    2014.05   (一社)化学とマイクロ・ナノシステム学会  

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    Country:Japan

  • The Springer Silver Scholar Award

    2013.05   Springer  

  • Best Poster Award, The 24th International Symposium on MicroScale Bioseparations (MSB) 2009

    2009.10   MSB  

  • Travel Award, The 24th International Symposium on MicroScale Bioseparations (MSB) 2009

    2009.10   MSB  

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Job Career (off-campus)

  • Osaka Metropolitan University   Department of Chemical Engineering, Graduate School of Engineering

    2022.04 - Now

  • National Institute of Science and Technology Policy(NISTEP), Ministry of Education, Culture, Sports, Science and Technology (MEXT)   External Expert (concurrently serve)

    2022.04 - Now

  • Kyushu University   Adjunct Lecturer

    2021.04 - 2022.03

  • The Japan Science and Technology Agency (JST)   PRESTO Researcher(concurrently serve)

    2018.04 - 2022.03

  • Osaka Prefecture Universit   Department of Chemical Engineering, Graduate School of Engineering   Associate Professor(Tenured)

    2016.04 - 2022.03

Papers

  • Flexible Glass-Based Hybrid Nanofluidic Device to Enable the Active Regulation of Single-Molecule Flows Reviewed

    Hiroto Kawagishi, Shun-ichi Funano, Yo Tanaka, Yan Xu

    Nano Letters   23 ( 6 )   2210 - 2218   2023.03( ISSN:1530-6984

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1021/acs.nanolett.2c04807

    PubMed

    Other URL: https://doi.org/10.1021/acs.nanolett.2c04807

  • 先端的分析化学のためのナノ流体デバイスの作製技術 Invited

    小林 丈,許岩

    ぶんせき   2023 ( 2 )   57 - 58   2023.02

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:Domestic journal  

  • Toward nanofluidics-based mass spectrometry for exploring the unknown complex and heterogeneous subcellular worlds Invited Reviewed

    Chantipmanee N., Xu Y.

    VIEW   4 ( 1 )   20220036   2023.02( ISSN:26883988

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1002/VIW.20220036

    Other URL: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85144407271&origin=inward

  • Nanofluidics for chemical and biological dynamics in solution at the single molecular level Invited Reviewed

    Chantipmanee N., Xu Y.

    TrAC - Trends in Analytical Chemistry   158   116877   2023.01( ISSN:01659936

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    DOI: 10.1016/j.trac.2022.116877

    Other URL: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85144407043&origin=inward

  • 1分子FRETと2-color二次元蛍光寿命相関分光法による核酸のマイクロ秒構造変化ダイナミクスの検出 Invited

    田中優仁, 許岩

    ぶんせき   2022 ( 7 )   261   2022.07

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    Authorship:Corresponding author   International / domestic magazine:Domestic journal  

  • Nanofluidics for sub-single cellular studies: Nascent progress, critical technologies, and future perspectives Invited Reviewed

    Jinbin Yang, Yan Xu

    Chinese Chemical Letters   33 ( 6 )   2799 - 2806   2022.06( ISSN:1001-8417

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    In the field of cell studies, there is a burgeoning trend to further downscale the investigation from a single-cell level to a sub-single-cell level. Subcellular matter is the basic content in cells and correlates with cell heterogeneity. Sub-single cellular studies focus on the subcellular matter in single cells and aim to understand the details and heterogeneity of individual cells in terms of the subcellular matter or even at the single component/vesicle/molecule level. Hence, sub-single cellular studies can provide deeper insights into fundamental cell biology and the development of new diagnostic and therapeutic technologies and applications. Nonetheless, the contents of a single cell are not only ultra-small in volume but also extremely complex in composition, far exceeding the capabilities of most tools used in current cell studies. We believe that nanofluidics holds great potential in providing ideal tools for sub-single cellular studies, not only because of their capability to handle femtoliter/attoliter-scale samples, but also because of their possibility to manipulate and analyze subcellular matters at the single component/vesicle/molecule level in a high-throughput manner. In this review, we summarize the efforts in the field of nanofluidics for sub-single cellular studies, focusing on nascent progress and critical technologies that have the potential to overcome the technical bottlenecks. Some challenges and future opportunities to integrate with information sciences are also discussed.

    DOI: 10.1016/j.cclet.2021.09.066

  • 研究室だより:大阪公立大学 大学院工学研究科化学工学分野 ナノ化学システム工学グループ(許研究室)

    許 岩

    電気学会論文誌E(センサ・マイクロマシン部門誌)   142 ( 5 )   NL5_2 - NL5_2   2022.05( ISSN:13418939

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    Authorship:Lead author, Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:Domestic journal  

    DOI: 10.1541/ieejsmas.142.nl5_2

  • Recent progress and perspectives in applications of 2-methacryloyloxyethyl phosphorylcholine polymers in biodevices at small scales Invited Reviewed

    Sasikarn Seetasang, Yan Xu

    Journal of Materials Chemistry B   10 ( 14 )   2323 - 2337   2022.04( ISSN:2050-750X

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    This review offers a bird's eye view of the development and application of 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers in small biodevices such as microfluidic devices, biosensors/bioprobes, artificial implants, and drug delivery systems.

    DOI: 10.1039/d1tb02675e

    PubMed

    Other URL: https://doi.org/10.1039/D1TB02675E

  • A biomimetic anti-biofouling coating in nanofluidic channels Invited Reviewed

    Sumire Fukuda, Yan Xu

    Journal of Materials Chemistry B   10 ( 14 )   2481 - 2489   2022.04( ISSN:2050-750X

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    Non-specific protein adsorption (NPA) is ubiquitous and generally considered a trigger for various biofoulings, adversely affecting diverse fields. Despite many approaches (generally polymer-based) available to combat NPA in a wide range of length scales, suppressing NPA in closed nanoscale spaces of emerging nanodevices such as nanofluidic devices remains a challenge due to the lack of suitable material and methodology to satisfy their ultra-small and closed features. In this study, a biomimetic, hydrosilane-functionalized 2-methacryloyloxyethyl phosphorylcholine (MPC) monomer material, which has tailored molecular characteristics and well-defined surface properties to overcome the challenges in the nanospaces, is elaborately designed and synthesized to form self-assembled, nanoscale, biomimetic coatings, enabling the efficient suppression of NPA in femtoliter-order, closed nanofluidic channels. The approach opens up a new path for exploring a strategic change of anti-biofouling coating from traditional polymer-based methodologies to a monomer-based methodology to overcome the challenge of suppressing NPA in closed nanospaces.

    DOI: 10.1039/d1tb02627e

    PubMed

  • Fabrication of Nanoscale Gas–Liquid Interfaces in Hydrophilic/Hydrophobic Nanopatterned Nanofluidic Reviewed

    Hiroto Kawagishi, Shuichi Kawamata, Yan Xu

    Nano Letters   21 ( 24 )   10555 - 10561   2021.12( ISSN:1530-6984

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)  

    Gas–liquid interfaces (GLIs) are ubiquitous and have found widespread applications in a large variety of fields. Despite the recent trend of downscaling GLIs, their nanoscale fabrication remains challenging because of the lack of suitable tools. In this study, a nanofluidic device, which has undergone precise local surface modification, is used in combination with tailored physicochemical effects in nanospace and optimized nanofluidic operations, to produce uniform, arrayable, stable, and transportable nanoscale GLIs that can concentrate molecules of interest at the nanoscale. This approach provides a delicate nanofluidic mechanism for downscaling gas–liquid interfaces to the nanometer scale, thus opening up a new avenue for gas–liquid interface studies and applications.

    DOI: 10.1021/acs.nanolett.1c02871

    PubMed

  • 細胞外小胞の単離, 分析技術の現状とナノ流体デバイスがもたらす新戦略

    Experimental Medicine   39 ( 20 )   170 - 177   2021.12

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    Authorship:Corresponding author  

  • Fabrication of nanoscale gas-liquid interfaces in hydrophilic/hydrophobic nanopatterned nanofluidic channels Reviewed

    Hiroto Kawagishi, Shuichi Kawamata, Yan Xu

    Nano Letters   21 ( 24 )   10555 - 10561   2021.10

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    Kind of work:Joint Work  

  • Nano-in-Nano Integration Technology for Advanced Fabrication of Functional Nanofluidic Devices

    Jinbin Yang, Yan Xu

    Advanced MEMS/NEMS Fabrication and Sensors   111 - 132   2021.10( ISBN:9783030797485

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    Publishing type:Part of collection (book)  

    DOI: 10.1007/978-3-030-79749-2_5

  • Nanofluidics for sub-single cellular studies: nascent progress, critical technologies, and future perspectives Reviewed

    Jinbin Yang, Yan Xu

    Chinese Chemical Letters   2021.09

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    Kind of work:Joint Work  

  • Fabrication of ultranarrow nanochannels with ultrasmall nanocomponents in glass substrates Invited Reviewed

    Hiroki Kamai, Yan Xu

    Micromachines   12 ( 7 )   2021.07

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)  

    Nanofluidics is supposed to take advantage of a variety of new physical phenomena and unusual effects at nanoscales typically below 100 nm. However, the current chip-based nanofluidic applications are mostly based on the use of nanochannels with linewidths above 100 nm, due to the restricted ability of the efficient fabrication of nanochannels with narrow linewidths in glass substrates. In this study, we established the fabrication of nanofluidic structures in glass substrates with narrow linewidths of several tens of nanometers by optimizing a nanofabrication process composed of electron-beam lithography and plasma dry etching. Using the optimized process, we achieved the efficient fabrication of fine glass nanochannels with sub-40 nm linewidths, uniform lateral features, and smooth morphologies, in an accurate and precise way. Furthermore, the use of the process allowed the integration of similar or dissimilar material-based ultrasmall nanocomponents in the ultranarrow nanochannels, including arrays of pockets with volumes as less as 42 zeptoliters (zL, 10−21 L) and well-defined gold nanogaps as narrow as 19 nm. We believe that the established nanofabrication process will be very useful for expanding fundamental research and in further improving the applications of nanofluidic devices.

    DOI: 10.3390/mi12070775

  • Advances in nanofluidics

    Yutaka Kazoe, Yan Xu

    Micromachines   12 ( 4 )   2021.04

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/mi12040427

  • Correction: Microfluidic flow control on charged phospholipid polymer interface.

    Yan Xu, Madoka Takai, Tomohiro Konno, Kazuhiko Ishihara

    Lab on a chip   21 ( 5 )   976 - 976   2021.03

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    Authorship:Lead author   International / domestic magazine:International journal  

    Correction for 'Microfluidic flow control on charged phospholipid polymer interface' by Yan Xu et al., Lab Chip, 2007, 7, 199-206, DOI: 10.1039/B616851P.

    DOI: 10.1039/d1lc90013g

    PubMed

  • Principles and applications of the nano-in-nano integration for multidisciplinary nanofluidics

    Jinbin Yang, Yan Xu

    Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip: Principles and Applications   407 - 428   2021.01( ISBN:9780444594327

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    Authorship:Corresponding author   Publishing type:Part of collection (book)  

    In this chapter, principles and applications of nano-in-nano integration which is a potential technology for multidisciplinary field are introduced. Currently, the ultrasmall volume of liquid confinement and the handling of molecules in such small volumes of liquids are the two challenging problems. Nanofluidics with nano-in-nano integration can solve these problems, because of their ultrasmall size and functional nanocomponents. Three nanofluidic applications, including molecule capture arrays, active nanovalves, and nanoelectrodes, were introduced. These proof-of-concept demonstrations revealed the infinite possibilities of nano-in-nano integration for multidisciplinary nanofluidics, which will offer a new pathway for next-generation scientific research.

    DOI: 10.1016/B978-0-444-59432-7.00012-1

  • Advances in Nanofluidics Micromachines Reviewed

    Micromachines   12 ( 4 )   2021

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    Kind of work:Joint Work  

  • Correction: Microfluidic flow control on charged phospholipid polymer interface Reviewed

    Lan on a Chip   ( 21 )   976 - 976   2021

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    Kind of work:Joint Work  

  • Functional coatings for lab-on-a-chip systems based on phospholipid polymers

    Yan Xu, Madoka Takai, Kazuhiko Ishihara

    Handbook of Modern Coating Technologies   555 - 595   2021

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    Authorship:Lead author, Corresponding author   Publishing type:Part of collection (book)  

    DOI: 10.1016/b978-0-444-63237-1.00016-4

  • Some Frontier Technologies for Aptamers in Medical Applications

    Yiyang Dong, Sai Wang, Lianhui Zhao, Jinbin Yang, Yan Xu

    Aptamers for Medical Applications   375 - 403   2021( ISBN:9789813348370

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    Publishing type:Part of collection (book)  

    DOI: 10.1007/978-981-33-4838-7_13

  • Aptamer-based nanofluidics for the molecular detection in ultra-small volume Reviewed

    Yang J, Kamai, H. Wang, Y. Xu Y

    2020   354 - 355   2020.10

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    Authorship:Corresponding author   Publishing type:Research paper (international conference proceedings)  

  • Generation of nanometer-scale geometrical gas-liquid interfaces in hydrophilic/hydrophobic patterned nanochannels Reviewed

    Kawagishi H. Kawamata, S. Xu Y

    Proceedings of Micro Total Analysis Systems   2020   190 - 191   2020.10

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    Authorship:Corresponding author   Publishing type:Research paper (international conference proceedings)  

  • Fabrication of sub-40-nanometer nano-in-nano structures in nanochannels Reviewed

    Kamai H, Xu Y

    Proceedings of Micro Total Analysis Systems   2020   366 - 367   2020.10

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    Authorship:Corresponding author   Publishing type:Research paper (international conference proceedings)  

  • 1分子制御化学に向けたアトリットル液滴のアレイ化と混合 Invited

    Kawagishi H, Xu Y

    Chemistry and Micro-Nano Systems   19 ( 1 )   29 - 30   2020.03

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)  

  • 1分子制御化学に向けたアトリットル液滴のアレイ化と混合

    川岸啓人, 許岩

    化学とマイクロ・ナノシステム 雑誌   19 ( 1 )   29 - 30   2020

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    Kind of work:Joint Work  

  • Fabrication of Sub-40-Nanometer nano-in-nano structures in nanofluidic channels Reviewed

    Proceedings of Micro Total Analysis Systems   2020   366 - 367   2020

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    Kind of work:Joint Work  

  • Aptamer-based nanofluidics for the molecular detection in ultra-small volume Reviewed

    Proceedings of Micro Total Analysis Systems   2020   354 - 355   2020

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    Kind of work:Joint Work  

  • Fabrication and evaluation of flexible nanovalves in 2D-nanochannels Reviewed

    Kawagishi H, Funano S, Tanaka Y, Kawamata S, Xu Y

    Proceedings of Micro Total Analysis Systems   2019   1182 - 1183   2019.10

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    Authorship:Corresponding author   Publishing type:Research paper (international conference proceedings)  

  • ナノ流体デバイスと光圧技術を融合した1分子DNA操作 Invited

    佐々木雄太, 西岡賢史, 島谷雄士, 許岩

    Chemistry and Micro-Nano Systems   18 ( 2 )   41 - 42   2019.10

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    Authorship:Corresponding author   Publishing type:Research paper (scientific journal)  

  • ナノ流体デバイスと光圧技術を融合した1分子DNA操作

    佐々木雄太,西岡賢史,島谷雄士,許岩

    化学とマイクロ・ナノシステム 雑誌   18 ( 2 )   41 - 42   2019

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    Kind of work:Joint Work  

  • Fabrication and evaluation of flexible nanovalves in 2D-nanochannels Reviewed

    Proceedings of Micro Total Analysis Systems   2019   1182 - 1183   2019

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    Kind of work:Joint Work  

  • Clarifying the behaviors of the nanoparticle trapped with an aifA device. Reviewed

    Proceedings of Micro Total Analysis Systems   2018   455 - 457   2018.10

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    Kind of work:Joint Work  

  • Creation of nanoparticle arrays by integration of nanofluidics and optical forces. Reviewed

    Proceedings of Micro Total Analysis Systems   2018   416 - 418   2018.10

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    Kind of work:Joint Work  

  • Analysis of streamlines in nanochannels by fluorescence imaging method. Reviewed

    Proceedings of Micro Total Analysis Systems   2018   447 - 449   2018.10

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    Kind of work:Joint Work  

  • Nanofluidics: a new arena for materials science Reviewed

    Advanced Materials   30   1 - 17   2018.03

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    Kind of work:Single Work  

  • Bridging world-to-nanofluidics interfaces through nano-in-nano integration technology Reviewed

    IEEE Micro-NanoMechatronics and Human Science(MHS)2016 International Symposium on   2016 ( 16603900 )   159 - 160   2016.11

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    Kind of work:Joint Work  

  • Soft Matter-Regulated Active Nanovalves Locally Self-Assembled in Femtoliter Nanofluidic Channels Reviewed

    Advanced Materials   2016 ( 28 )   2209 - 2216   2016.01

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    Kind of work:Joint Work  

  • On-Chip Cell Preservation by Using a Phospholipid Polymer Hydrogel Reviewed

    Journal of the Japan Society of colour Material   2016   2016

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    Kind of work:Joint Work  

  • A Technique Enabling the Active Regulation of Femtoliter-Scale Liquids Reviewed

    Journal of Society of Automotive Engineers of Japan   70 ( 9 )   122 - 123   2016

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    Kind of work:Joint Work  

  • Antifouling Surface Modification of Nanochannels Using a Silanized Phospholipid Monomer Reviewed

    Proceedings of Micro Total Analysis Systems 2016   2016 ( 1 )   1152 - 1153   2016

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    Kind of work:Joint Work  

  • ナノ流路で開閉可能な超微小スマートバルブ──フェムトリットル単位の液体を自在に制御 Reviewed

    許岩, 原田敦史

    化学 雑誌   71 ( 7 )   36 - 39   2016

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    Kind of work:Joint Work  

  • Spontaneous Packaging and Hypothermic Storage of Mammalian Cells with a Cell-Membrane-Mimetic Polymer Hydrogel in a Microchip Reviewed

    ACS Applied Materials & Interfaces   2015 ( 7 )   23089 - 23097   2015.10

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    Kind of work:Joint Work  

  • An Integrated Glass Nanofluidic Device Enabling in situ Electrokinetic Probing of Water Confined in a Single Nanochannel under Pressure-Driven Flow Conditions Reviewed

    Small   2015 ( 11 )   2015.10

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    Kind of work:Joint Work  

  • Formation of submicron particle arrays by utilizing nanowells in nanochannels Reviewed

    Proceedings of Micro Total Analysis Systems 2015   2015 ( 1 )   1556 - 1558   2015.10

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    Kind of work:Joint Work  

  • Regeneration of Glass Nanofluidic Chips through a Multiple-Step Sequential Thermochemical Decomposition Process at High Temperatures Reviewed

    Lab on a Chip   2015 ( 15 )   3856 - 3861   2015.08

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    Kind of work:Joint Work  

  • Flexible and In-Situ Fabrication of Nanochannels with High Aspect Ratios and Nanopillar Arrays in Fused Silica Substrates Utilizing Focused Ion Beam Reviewed

    RSC Advances   2015 ( 5 )   50638 - 50643   2015.05

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    Kind of work:Joint Work  

  • Site-Specific Nanopatterning of Functional Metallic and Molecular Arbitrary Features in Nanofluidic Channels Reviewed

    Lab on a Chip   2015 ( 15 )   1989 - 1993   2015.03

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    Kind of work:Joint Work  

  • An Integrated Glass Nanofluidic Device Enabling in situ Electrokinetic Probing of Water Confined in a Single Nanochannel under Pressure-Driven Flow Conditions Reviewed

    ( 11 )   6165 - 6171   2015

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    Kind of work:Joint Work  

  • Site-Specific Nanopatterning of Functional Metallic and Molecular Arbitrary Features in Nanofluidic Channels Reviewed

    ( 15 )   2015

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    Kind of work:Joint Work  

  • Regeneration of Glass Nanofluidic Chips through a Multiple-Step Sequential Thermochemical Decomposition Reviewed

    ( 15 )   2015

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    Kind of work:Joint Work  

  • Design, synthesis and characterization of a thiolated temperature-responsive polymer for smart nanofluidic control Reviewed

    Proceedings of Micro Total Analysis Systems 2014   2014 ( 1 )   1841 - 1843   2014.10

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    Kind of work:Joint Work  

  • マイクロ・ナノ空間の機能化表面・界面の構築と制御 Reviewed

    許岩

    化学とマイクロ・ナノシステム 雑誌   13 ( 2 )   2014.10

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  • Aptamer and its potential applications for food safety Reviewed

    Critical Reviews in Food Science and Nutrition   2014 ( 54 )   1548 - 1561   2014

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  • Determination of Cattle Foot-and-Mouth Disease Virus by micro-ELISA Method Reviewed

    Analytical Science   2014 ( 30 )   359 - 363   2014

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  • Arbitrary nanopatterning inside nanochannels by integration of top-down and bottom-up approaches for single molecule analysis Reviewed

    Proceedings of Micro Total Analysis Systems 2013   2013 ( 1 )   119 - 121   2013.10

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    Kind of work:Joint Work  

  • Bonding of glass nanofluidic chips at room temperature by a one-step surface activation using an O2/CF4 plasma treatment Reviewed

    Lab on a Chip   2013 ( 13 )   1048 - 1052   2013.01

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    Kind of work:Joint Work  

  • Development of fluorine induced plasma activating room-temperature bonding stratage for high-pressure micro-nano fluidic devices Reviewed

    Proceedings of Micro Total Analysis Systems 2012   2012 ( 1 )   1237 - 1239   2012.12

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  • Femtoliter droplet handling in nanofluidic channels: a Laplace nanovalve Reviewed

    Analytical Chemistry   2012 ( 84 )   10812 - 10816   2012.12

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    Kind of work:Joint Work  

  • Temperature-flexible cell microcontainers fabricated with a phosphorylcholine polymer hydrogel on chip Reviewed

    Proceedings of Micro Total Analysis Systems 2012   2012 ( 1 )   1048 - 1050   2012.12

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    Kind of work:Joint Work  

  • Nano Laplace valve for femtolitter liquid generation and handling realized by nanopillar-in-nanochannel fabrication and surface modification Reviewed

    Proceedings of Micro Total Analysis Systems 2012   2012 ( 1 )   1447 - 1449   2012.10

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    Kind of work:Joint Work  

  • A room-temperature bonding of glass nanofluidic chips utilizing a surface activation with a fluorine-containing plasma treatment Reviewed

    Proceedings of Micro Total Analysis Systems 2012   2012 ( 1 )   1225 - 1227   2012.10

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    Kind of work:Joint Work  

  • Micropatterning of biomolecules on a glass substrate in fused silica microchannels by using photolabile linker-based surface activation Reviewed

    Microchimica Acta   2012 ( 179 )   49 - 55   2012.07

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    Kind of work:Joint Work  

  • Development of microfluidic platform for single-cell secretion analysis using a direct photoactive cell-attaching method Reviewed

    Analytical Sciences   2011 ( 27 )   973 - 978   2012.01

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    Kind of work:Joint Work  

  • Low-temperature direct bonding of glass nanofluidic chips using a two-step plasma surface activation process Reviewed

    Analytical and Bioanalytical Chemistry   2012 ( 402 )   1011 - 1018   2012.01

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    Kind of work:Joint Work  

  • Microchip-based cellular biochemical systems for practical applications and fundamental research: from microfluidics to nanofluidics Reviewed

    Analytical and Bioanalytical Chemistry   2012 ( 402 )   99 - 107   2012.01

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    Kind of work:Joint Work  

  • Development of Cell Chips based on Biocompatible Polymers Reviewed

    Journal of Japanese Society for Biomaterials   2012 ( 30-3 )   159 - 167   2012

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    Kind of work:Joint Work  

  • Laplace pressure valve utilizing nano-in-nano structure toward attoliter scale liquid handling Reviewed

    2011 ( 1 )   1068 - 1070   2011.10

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    Kind of work:Joint Work  

  • Rapid screening swine foot-and-mouth disease virus using micro-ELISA system Reviewed

    Lab on a Chip   2011 ( 11 )   2153 - 2155   2011.07

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    Kind of work:Joint Work  

  • Low temperature bonding of glasses by means of surface activation using water Reviewed

    Proceedings of 25th Spring Conference of Japan Institute of Electronics Packaging   2011 ( 1 )   340 - 342   2011

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    Kind of work:Joint Work  

  • Phospholipid polymer biointerfaces for lab-on-a-chip devices Reviewed

    Annals of Biomedical Engineering   2010 ( 38 )   1938 - 1953   2010

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    Kind of work:Joint Work  

  • Cell-based toxin screening integrated with a cell-sustainable hydrogel on chip for onsite and portable application Reviewed

    Proceedings of Micro Total Analysis Systems   2010 ( 1 )   1499 - 1501   2010

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    Kind of work:Joint Work  

  • The biological performance of cell-containing phospholipid polymer hydrogels in bulk and microscale form Reviewed

    Biomaterials   2010 ( 31 )   8839 - 8846   2010

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    Kind of work:Joint Work  

  • Single-cell attachment and culture method using a photochemical reaction in a closed microfluidic system Reviewed

    Biomicrofluidics   2010 ( 4 )   2010

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    Kind of work:Joint Work  

  • A microfluidic hydrogel capable of cell preservation without perfusion culture under cell-based assay conditions Reviewed

    Advanced Materials   2010 ( 22 )   3017 - 3021   2010

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    Kind of work:Joint Work  

  • An efficient surface modification using 2-methacryloyloxyethyl phosphorylcholine to control cell attachment via photochemical reaction in a microchannel Reviewed

    Lab on a Chip   2010 ( 10 )   1937 - 1945   2010

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    Kind of work:Joint Work  

  • Suppression of protein adsorption on a charged phospholipid polymer interface Reviewed

    Biomacromolecules   2009 ( 10 )   267 - 274   2009

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    Kind of work:Joint Work  

  • An on-chip living cell bank Reviewed

    Proceedings of Micro Total Analysis Systems   2009 ( 2 )   1952 - 1954   2009

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    Kind of work:Joint Work  

  • Protein adsorption and cell adhesion on cationic, neutral, and anionic 2-methacryloyloxyethyl phosphorylcholine copolymer surfaces Reviewed

    Biomaterials   2009 ( 30 )   4930 - 4938   2009

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    Kind of work:Joint Work  

  • Functional biointerface for microfluidic devices using phospholipid polymers Reviewed

    KOBUNSHI RONBUNSHU   65 ( 3 )   228 - 234   2008.03

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    Kind of work:Joint Work  

  • Long-term storage of living cells on chip for cell-based assays Reviewed

    Proceedings of Micro Total Analysis Systems   2008 ( 2 )   1852 - 1854   2008

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    Kind of work:Joint Work  

  • Charged phospholipid polymer surfaces with high cell adhesion resistance for cell chip Reviewed

    Proceedings of Micro Total Analysis Systems   2007 ( 1 )   424 - 426   2007

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    Kind of work:Joint Work  

  • Microfluidic flow control on charged phospholipid polymer interface Reviewed

    Lab on a Chip   2007 ( 7 )   199 - 206   2007

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    Kind of work:Joint Work  

  • Coating of anionic phospholipid polymer onto silica-based microchannel to minimize nonspecific protein adsorption Reviewed

    Key Engineering Materials   2007 ( 342-343 )   797 - 800   2007

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    Kind of work:Joint Work  

  • Protein antiadsorption modification by negatively charged phospholipid polymer for microsystem needing electroosmotic flow Reviewed

    Proceedings of Micro Total Analysis Systems   2006 ( 1 )   215 - 217   2006

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    Kind of work:Joint Work  

  • Constructing biomembrane-mimic interface for cell separation in microfluidic chip Reviewed

    Transactions of Materials Research Society of Japan   2006 ( 31 )   645 - 648   2006

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    Kind of work:Joint Work  

  • Preparation of the soft tissue bulking agent composed of calcium alginate microspheres and its resorption in vivo Reviewed

    Chinese Journal of Biomedical Engineering   2004 ( 23 )   448 - 454   2004

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    Kind of work:Joint Work  

  • The study on the PTC effect of CNT/CB filled PE composite Reviewed

    China Synthetic Resin and Plastics   2002 ( 19 )   4 - 7   2002

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    Kind of work:Joint Work  

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Books and Other Publications

  • Advanced MEMS/NEMS Fabrication and Sensors

    Springer  2021.10  ( ISBN:3030797481

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    Total pages:318  

    ASIN

  • Nano-in-nano integration technology for advanced fabrication of functional nanofluidic devices, in 'Advanced MEMS/NEMS Fabrication and Sensors'

    Yang Jinbin, Yan Xu( Role: Joint author)

    Springer Nature  2021.10  ( ISBN:978-3-030-79748-5

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    Responsible for pages:111-132  

  • Principles and applications of the nano-in-nano integration for multidisciplinary nanofluidics, in 'Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip: Principles and Applications, 1st Edition'

    Yang Jinbin, Yan Xu( Role: Sole author)

    Elsevier  2021.09  ( ISBN:978-0-444-59432-7

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    Responsible for pages:407-428  

  • Multidisciplinary microfluidic and nanofluidic lab-on-a-chip : principles and applications

    Elsevier  2021.09  ( ISBN:9780444594327

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    Total pages:xxii, 462 p.  

    CiNii Books

  • Aptamers for Medical Applications: From Diagnosis to Therapeutics

    Springer  2021.03  ( ISBN:9813348372

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    Total pages:475  

    ASIN

  • Some frontier technologies for aptamers, in medical applications, in 'Aptamers for Medical Applications. From Diagnosis to Therapeutics'

    Dong Y., Wang S., Zhao L., Yang J., Xu Y.( Role: Joint author)

    Springer Nature  2021.03  ( ISBN:978-9813348370

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    Responsible for pages:375-403  

  • Functional coatings for lab-on-a-chip systems based on phospholipid polymers, in 'Handbook of Modern Coating Technologies. Applications and Development '

    Xu Y., Takai M., Ishihara K.( Role: Joint author)

    Elsevier  2021.03  ( ISBN:978-0444632395

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    Responsible for pages:555-595  

  • Handbook of Modern Coating Technologies. Future Perspectives and Advanced Applications

    Yan Xu( Role: Contributor ,  Functional Coatings for Lab-on-a-Chip Systems Based on Phospholipid Polymers)

    Elsevier  2021.03 

  • Beyond Shanghai and PISA : cognitive and non-cognitive competencies of Chinese students in mathematics

    Xu Binyan, Zhu Yan, Lu Xiaoli

    Springer  2021  ( ISBN:9783030681562

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  • Beyond Phenomena: Functionalization of Nanofluidics Based on Nano-in-Nano Integration Technology, in `21st Century Nanoscience - A Handbook, Exotic Nanostructures and Quantum Systems (Volume Five)'

    Xu Y.( Role: Sole author)

    Taylor & Franciss (CRC Press)   2020.04  ( ISBN:978-0815356264

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    Responsible for pages:13-1~13-18  

  • 21st Century Nanoscience - A Handbook, Exotic Nanostructures and Quantum Systems (Volume Five)

    Yan Xu( Role: Contributor ,  Beyond Phenomena: Functionalization of Nanofluidics based on Nano-in-Nano Integration Technology)

    Taylor & Francis (CRC Press), in press  2020.04 

  • Cytocompatible hydrogel composed of phospholipid polymers for regulation of cell functionalities. `Polymers in Nanomedicine'

    Kazuhiko Ishihara, Yan Xu, Tomohiro Konno( Role: Joint author)

    Springer Berlin/Heidelberg  2011.01 

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    Responsible for pages:141-165  

    DOI: 10.1007/12_2011_151

  • ナノメディシンの分子科学

    Xu Yan( Role: Contributor ,  1細胞内環境の特徴を有するナノチャネルを用いた細胞死に関わる生体分子の1分子計測)

    講談社サイエンティフィク, in press 

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MISC

  • 細胞外小胞の単離,分析技術の現状とナノ流体デバイスがもたらす新戦略

    村田幸作,許岩

    羊土社 実験医学   39 ( 20 )   170 - 177   2021.12

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  • 【EVs 細胞外小胞の生物学 エクソソームをはじめとする多様な小胞の生理・病理の理解と新しい解析法】(第4章)細胞外小胞研究の新技術 細胞外小胞の単離、分析技術の現状とナノ流体デバイスがもたらす新戦略

    村田 幸作, 許 岩

    実験医学   39 ( 20 )   3280 - 3287   2021.12( ISSN:0288-5514

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    細胞外小胞の一種であるエクソソームはタンパク質、mRNA、miRNAなどの生体分子を有することから、さまざまな生命現象にかかわっていることがわかっている。現在、エクソソームの生物学的意義の解明とそれを対象とした診療技術の開発における最も大きな課題は、粒径の小ささ(100nm前後)に起因したエクソソームの単離や分析の困難さにあるといえる。現状、多くのエクソソームの分析では、「エクソソームを濃縮して解析する」という戦略がとられている。本稿では、この戦略に基づいたエクソソームの単離、分析技術の現状と課題について述べる。その後、最先端のナノ流体デバイス技術を用いた、「濃縮せずに1個のエクソソームでも検出、解析できるようにする」という全く新しい戦略について紹介する。(著者抄録)

  • 一分子を操作するための超微小液滴の制御技術を開発

    Kawagishi H. Kawamata, S. Xu Y

    30 - 30   2019.07

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    Authorship:Corresponding author   Publishing type:Article, review, commentary, editorial, etc. (other)  

Presentations

  • 超越分子システム構築に向けたナノ流体デバイスにおける酵素内包ナノゲルの特性評価 Domestic conference

    土手勇介, 黄学進, 高井まどか, 許岩

    学術変革領域研究(A) 分子サイバネティクス・超越分子システム合同シンポジウム2023  2023.03 

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    Presentation type:Poster presentation  

    Venue:東京  

  • 単一エクソソームアレイとその応用 Invited Domestic conference

    許岩

    第6回 大阪公立大学アカデミア創薬シンポジウム「エクソソームと次世代創薬」  2023.03 

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    Presentation type:Oral presentation (invited, special)  

    Venue:大阪  

  • 1分子制御化学のための様々な溶媒によるアトリットル液滴の作製と評価 Domestic conference

    小林丈,許岩

    日本分析化学会第71年会  2022.09 

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    Presentation type:Poster presentation  

    Venue:岡山大学津山キャンパス  

  • ナノ流体デバイスで創るナノゲルファイバー酵素分子システムのボトムアップ構築 Domestic conference

    許岩

    学術変革領域研究(A)「超越分子システム」領域 第2回領域会議  2022.09 

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    Presentation type:Poster presentation  

    Venue:北海道  

  • ナノ流体デバイスで創るナノゲルファイバー酵素分子システムのボトムアップ構築 Domestic conference

    許岩

    学術変革領域研究(A)「超越分子システム」領域 第2回領域会議  2022.09 

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    Presentation type:Oral presentation (general)  

    Venue:北海道  

  • 1 分子制御化学に向けた固液界面による均一なアトリットル液滴の作製 Domestic conference

    田中 優仁,許岩

    学術変革領域研究(A)「超越分子システム」領域 第2回領域会議  2022.09 

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    Venue:北海道  

  • 超越分子システムのボトムアップ構築のための ナノ流体デバイスにおける単一ナノ物質のホログラフィック光圧操作 Domestic conference

    田中 宗玄,許岩

    学術変革領域研究(A)「超越分子システム」領域 第2回領域会議  2022.09 

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    Presentation type:Poster presentation  

    Venue:北海道  

  • ナノ流体デバイスを用いた単一リポソームの操作 Domestic conference

    宮田 宗慈,許岩

    学術変革領域研究(A)「超越分子システム」領域 第2回領域会議  2022.09 

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    Presentation type:Poster presentation  

    Venue:北海道  

  • ナノ流体デバイスによる酵素を内包したナノゲルのアレイ化と光圧操作 Domestic conference

    土手 勇介,許岩

    学術変革領域研究(A)「超越分子システム」領域 第2回領域会議  2022.09 

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    Presentation type:Poster presentation  

    Venue:北海道  

  • 1分子制御化学のための様々な溶媒によるアトリットル液滴の作製と評価 Domestic conference

    小林丈,許岩

    学術変革領域研究(A)「超越分子システム」若手会  2022.09 

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    Venue:北海道  

  • ナノ流体デバイスによる酵素を内包したナノゲルのアレイ化と光圧操作 Domestic conference

    土手 勇介,許岩

    学術変革領域研究(A)「超越分子システム」若手会  2022.09 

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    Presentation type:Poster presentation  

    Venue:北海道  

  • aifAを用いた単一エクソソームの表面膜たんぱく質の不均一性解析 Domestic conference

    玉置 大悟, 許岩

    学術変革領域研究(A)「超越分子システム」若手会  2022.09 

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    Presentation type:Poster presentation  

    Venue:北海道  

  • Pioneering Nanofuidics for New Chemistry, Biology, and Materials Science Invited International conference

    Yan Xu

    Pre-conference Lecture Series of the 13th International Conference of the Chinese Society of Micro-Nano Technology (CSMNT 2022)  2022.07 

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    Presentation type:Oral presentation (invited, special)  

  • 1分子反応場のためのナノ流体デバイスによる単一リポソームの操作 Domestic conference

    宮田宗慈, 新井裕貴, 許岩

    学術変革領域研究A関西リージョナルミーティング  2022.07 

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    Presentation type:Oral presentation (general)  

    Venue:北海道  

  • 1分子制御化学による単一分子反応ダイナミクスの直接観察 Domestic conference

    小林丈,許岩

    学術変革領域研究A関西リージョナルミーティング  2022.07 

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    Presentation type:Oral presentation (general)  

    Venue:大阪公立大学  

  • 単一分子測定に向けたナノ流路内脂質二重膜の形成 Domestic conference

    川岸啓人, 老木成稔, 岩本真幸, 許岩

    学術変革領域研究A関西リージョナルミーティング  2022.07 

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    Presentation type:Oral presentation (general)  

    Venue:大阪公立大学  

  • ナノ流体デバイスが拓く新しい分子システム Domestic conference

    許岩

    学術変革領域研究A関西リージョナルミーティング  2022.07 

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    Presentation type:Oral presentation (general)  

    Venue:大阪公立大学  

  • aifAを用いた単一エクソソームの表面膜たんぱく質の不均一性解析 Domestic conference

    玉置大悟, 佐藤雄介,高橋暁子,田中陽子,中澤知香,許岩

    化学とマイクロ・ナノシステム学会第45回研究会 (CHEMINAS45)  2022.05 

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    Presentation type:Oral presentation (general)  

    Venue:中央大学後楽園キャンパス  

  • 1分子制御化学のためのナノ流体デバイス中での固液界面によるアトリットル液滴の形成 Domestic conference

    田中優仁,川岸啓人,許岩

    化学とマイクロ・ナノシステム学会第45回研究会 (CHEMINAS45)  2022.05 

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    Presentation type:Oral presentation (general)  

    Venue:中央大学後楽園キャンパス  

  • ナノ流体デバイスが拓く新しい化学 Invited Domestic conference

    許 岩

    日本分析化学会近畿支部・支部講演会  2022.04 

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    Presentation type:Oral presentation (invited, special)  

  • ナノ流体デバイスが拓く新しい化学 Invited

    許 岩

    第41回キャピラリー電気泳動シンポジウム (SCE2021) -限界を打破する新技術-  2021.12 

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    Presentation type:Oral presentation (invited, special)  

  • ナノ流体デバイスが拓く新しい物質化学 Invited

    許 岩

    九州大学先導物質化学研究所セミナー  2021.12 

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    Presentation type:Oral presentation (invited, special)  

  • ナノ流体デバイスが拓くエクソソーム計測の新戦略と最前線 Invited

    許 岩

    日本粉体工業技術協会計装測定分科会・バイオ粒子プロセス分科会合同分科会「バイオ粒子計測の現状と課題」  2021.12 

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    Presentation type:Oral presentation (invited, special)  

  • さきがけ「生体における微粒子の機能と制御」成果報告会〜微粒子を追う、捕まえる、操る〜 aifAによるエクソソームの1ステップ単離配列と1粒子統合解析

    許 岩

    日本生化学会大会プログラム・講演要旨集  2021.11  (公社)日本生化学会

  • 高分子によるナノ流体デバイスの高機能化 Invited

    許 岩

    高分子によるナノ流体デバイスの高機能化  2021.09 

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    Presentation type:Oral presentation (general)  

  • Nanofluidic Optical Manipulation (NOM) Invited

    Yan Xu

    International Symposium on Microfluidics and BioMEMS  2021.04 

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    Presentation type:Oral presentation (keynote)  

  • ナノ流体デバイス用いたエクソソームの1粒子単離配列と解析 Invited

    Xu Y

    The 43rd Annual Meeting of the Molecular Biology Society of Japan  2020.12 

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    Presentation type:Oral presentation (invited, special)  

  • Nanofluidics for New Chemistry, Biology, and Materials Science Invited

    Xu Y

    The 137th Meeting of The Analytical Technology Workshop  2020.11 

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    Presentation type:Oral presentation (invited, special)  

  • ナノ流体デバイスによるエクソソームの1ステップ配列と1粒子解析 Invited

    Xu Y

    The 58th Annual Meeting of the Biophysical Society of Japan  2020.09 

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    Presentation type:Oral presentation (invited, special)  

  • ナノ流体デバイスを用いたエクソソームの簡便単離、1粒子配列及び統合解析 Invited

    Xu Y

    The 58th Annual Meeting of the Biophysical Society of Japan  2020.09 

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    Presentation type:Oral presentation (invited, special)  

  • ナノ流体デバイスによるエクソソームの1ステップ配列と1粒子解析

    許 岩

    日本分析化学会講演要旨集  2020.09  (公社)日本分析化学会

  • ナノ流体デバイスを用いたエクソソームの簡便単離、1粒子配列及び統合解析(Simple isolation and integrated analysis of single exosomes on an aifA chip)

    許 岩

    生物物理  2020.08  (一社)日本生物物理学会

  • Pioneering Nanofluidics for New Chemistry, Biology, and Materials Science Invited

    Xu Y

    Special Lecture at Beihang University  2019.12 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Nanofluidics for new chemistry, biology, and materials science Invited

    Xu Y

    Invited talk at the University of Tokyo  2019.11 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Towards molecular manual-assembly: nanofluidic manipulation of single nanometric objects and extracellular vesicles Invited

    Xu Y

    The 2nd Symposium for Cell Analysis on Micro/Nanofluidics,  2019.09 

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    Presentation type:Oral presentation (keynote)  

  • Pioneering nanofluidics for new chemistry, biology, and materials science Invited

    Xu Y

    Special Lecture at Changzhou University  2019.09 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Pioneering nanofluidics for new chemistry, biology, and materials science Invited

    Xu Y

    Special Lecture at International Iberian Nanotechnology Laboratory (INL)  2019.09 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Pioneering nanofluidics for new chemistry, biology, and materials science Invited

    Xu Y

    DICP 70th Anniversary Forum  2019.08 

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    Presentation type:Oral presentation (invited, special)  

  • Pioneering Nanofluidics for New Chemistry, Biology, and Materials Science Invited

    Xu Y

    Special Lecture at Northeastern University  2019.08 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Pioneering nanofludics for new chemistry, biology, and materials science Invited

    Xu Y

    2019.08 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Beyond phenomena: pioneering applied nanofluidics Invited

    Xu Y

    Special Lecture at Shanghai University of Traditional Chinese Medicine  2019.07 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • Nanofluidic detection and manipulation of single nanoparticles and extracellular vesicles Invited

    Xu Y

    The 9th International Multidiscipline Conference on Optofluidics (IMCO 2019)  2019.06 

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    Presentation type:Oral presentation (invited, special)  

  • Pioneering nanofludics for new chemistry, biology, and materials science Invited

    Xu Y

    Special Lecture at NAIST  2019.06 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • What can we expect with nanofluidics? An exciting arena for new chemistry, biology, and materials science Invited

    Xu Y

    The 11th International Symposium on Microchemistry and Microsystems (ISMM2019)  2019.05 

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    Presentation type:Oral presentation (invited, special)  

  • Nanofluidic arrays allowing high-throughput detection and manipulation of single nanoparticles and extracellular vesicles Invited

    Xu Y

    The 14th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2019)  2019.04 

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    Presentation type:Oral presentation (invited, special)  

  • Pioneering nanofluidics for new Chemistry, biology, and materials science Invited

    Xu Y

    The BDR Symposium 2019, Control and design of biosystems  2019.03 

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    Presentation type:Oral presentation (invited, special)  

  • Pioneering and advancing nanofluidics for new chemistry, biology, and materials science Invited

    Xu Y

    Special Lecture at New York University (NYU)  2019.03 

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    Presentation type:Oral presentation (invited, special)  

  • Arraying, detection and manipulation of single nanoparticles and exosomes by a nanofluidic aL-in-fL Array (aifA) Invited

    Xu Y

    The Pittsburg Conference and Exposition-The Annual Conference 2019 (PITTCON 2019)  2019.03 

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    Presentation type:Oral presentation (invited, special)  

  • Pioneering nanofluidics for new chemistry, biology, and materials science Invited

    Xu Y

    Special Lecture at Pennsylvania State University  2019.03 

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    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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Works

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Industrial Property Rights

  • 粒子捕捉装置及び粒子捕捉方法

    許岩

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    property_type:Patent 

    Application no:2019-518882 

    Patent/Registration no:特許第7104988号 

  • 粒子収集装置及び粒子径分布測定方法

    Yan Xu

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    property_type:Patent 

    Application no:特願2020-083270号 

  • 粒子捕捉装置及び粒子捕捉方法

    Yan Xu

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    property_type:Patent 

    Application no:中国特許出願201880032643.0 

  • 粒子捕捉装置及び粒子捕捉方法

    Yan Xu

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    property_type:Patent 

    Application no:米国特許出願16/614,112 

Outline of collaborative research (seeds)

  • エクソソームの1ステップ単離配列と1粒子統合解析

Joint research

  • 1細胞情報の二次元化による細胞内分子計数

    JSPS  国際共同研究加速基金(国際共同研究強化(B))  2022.04

Charge of on-campus class subject

  • 化学工学実験I

    2022   Weekly class   Undergraduate

  • 初年次ゼミナール

    2022   Weekly class   Undergraduate

  • 物質化学生命系特別演習

    2022   Intensive lecture   Graduate school

  • 物質化学生命系特別演習第1

    2022   Intensive lecture   Graduate school

  • 物質化学生命系特別演習第2 (化学工学分野)

    2022   Intensive lecture   Graduate school

  • 化学工学・プロセス工学特論2 (化学工学分野)

    2022   Weekly class   Graduate school

  • 化学工学・プロセス工学特論1 (化学工学分野)

    2022   Weekly class   Graduate school

  • 物質化学生命系特別研究 (化学工学分野)

    2022   Intensive lecture   Graduate school

  • Recent Advances in Engineering

    2021    

  • First Year Seminar

    2021    

  • Advanced Chemical Engineering and Process Technology II

    2021    

  • Advanced Chemical Engineering and Process Technology I

    2021    

  • Laboratory: Chemical Engineering I

    2021   Practical Training  

  • Advanced Chemical Engineering and Process Technology II

    2021    

  • Advanced Chemical Engineering and Process Technology I

    2021    

  • First Year Seminar

    2021    

  • Laboratory: Chemical Engineering I

    2021   Practical Training  

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Faculty development activities

  • 「論文発表のインパクトを爆アゲしよう!〜論文公開したときにやるべき研究広報〜」  2022

  • 工学FD集会 教育改善のための、ポートフォリオシステム「てぃら・みす」活用法  2022

Original item・Special report (Education Activity)

  • 2022

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    Special report:学生の受賞
    2023/3 小林 丈 化工研究業績賞
    2023/2 小林 丈 修士研究発表賞@化学工学分野修士論文発表会
    2023/2 玉置 大悟 ポスター発表優秀賞@化学工学分野博士前期課程中間発表会
    2023/2 田中 優仁 ポスター発表優秀賞@化学工学分野博士前期課程中間発表会

Social Activities

  • 文部科学省 科学技術・学術政策研究所 専門調査員

    Role(s): Official expert

    文部科学省 科学技術・学術政策研究所  2022.04 - 2023.03

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    SDGs:

    Type:Cooperation with government and educational institutions

  • 九州大学先導物質化学研究所セミナー ナノ流体デバイスが拓く新しい物質化学

    2021.04 - 2022.03

  • 日本粉体工業技術協会計装測定分科会・バイオ粒子プロセス分科会合同分科会「バイオ粒子計測の現状と課題」 ナノ流体デバイスが拓くエクソソーム計測の新戦略と最前線

    2021.04 - 2022.03

  • 分析技術研究会(企業技術者向け) Nanofluidics for New Chemistry, Biology, and Materials Science

    2020.04 - 2021.03

  • 日本分析化学会近畿支部幹事

    Role(s): Logistic support

    2019.04 - 2023.03

  • 奈良先端科学技術大学院大学光ナノサイエンス特別講義 Pioneering nanofludics for new chemistry, biology, and materials science

    2019.04 - 2020.03

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Media Coverage

  • 大阪公立大と理研 極微小バルブで一分子の流れを制御 Newspaper, magazine

    日刊ケミカルニュース  日刊ケミカルニュース  2023.03

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    SDGs:

  • 大阪公立大学などが極微小バルブで1分子の流れを制御、医療・産業用材料に Newspaper, magazine

    日経  日経クロステック(xTECH)  2023.03

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    SDGs:

  • Yan Xu @OsakaMetUniv reports a nanofluidic valve to enable the active regulation of single-molecule flows, thus opening avenues for single-molecule regulated chemical/biological processes. Read the paper 👉��� https://go.acs.org/4ig Internet

    ACS (Nano Letters Twitter)  2023.03

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    SDGs:

  • 公大ら,極微小バルブで1分子の流れを制御 Internet

    OPTRONICS ONLINE  OPTRONICS ONLINE  2023.03

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    SDGs:

  • 物質化学生命系専攻化学工学分野 許 岩准教授らのグループと 理化学研究所との共同研究の成果がAmericanChemicalSocietyが刊行する 「Nano Letters」に掲載されました。 Internet

    大阪公立大学工学研究科  大阪公立大学工学研究科ウェブサイト  2023.03

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    SDGs:

  • <専業用材料から医療診断技術まで>極微小バルブで1分子の流れの制御に成功―化学・生化学合成のパラダイムシフトに期待― Internet

    大阪公立大学・理研  大阪公立大学・理研 共同プレスリリース  https://www.riken.jp/press/2023/20230307_2/index.html  2023.03

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    SDGs:

  • 工学研究科 許 岩准教授らの論文が「View」誌の表紙に採用 Internet

    大阪公立大学  大阪公立大学ウェブサイト  2023.02

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    SDGs:

  • 工学研究科 物質化学生命系専攻 化学工学分野の許 岩准教授、Nattapong Chantipmanee研究員らの研究グループの論文が国際学術誌「View」誌の表紙に採用されました。 Internet

    大阪公立大学工学研究科  大阪公立大学工学研究科ウェブサイト  2023.02

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    SDGs:

  • 研究成果が複数の海外のニュースサイトにて紹介、転載されました Internet

    Phys.org、 Mirage News、 AZoM、 Analytica World、 analytica-world.com、Bioengineer.org、 Innovations Report、 Nanowerk, ScienceDaily 等  Phys.org、 Mirage News、 AZoM、 Analytica World、 analytica-world.com、Bioengineer.org、 Innovations Report、 Nanowerk, ScienceDaily 等  2023.02

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    SDGs:

  • Nanofluidic devices offer solutions for studying single molecule chemical reactions Internet

    OMU Web、EurekAlert!、 Alpha Galileo、 Asia Research News  OMU Web、EurekAlert!、 Alpha Galileo、 Asia Research News、 OMU Facebook 、 OMU Twitter  https://www.asiaresearchnews.com/content/nanofluidic-devices-offer-solutions-studying-single-molecule-chemical-reactions  2023.02

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    SDGs:

  • View誌(2023年4巻1号)の表紙 Newspaper, magazine

    Wiley  View  2023.02

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    SDGs:

  • 物質化学生命系専攻 化学工学分野 許岩准教授、Nattapong Chantipmanee研究員の研究成果が、国際学術誌「TrAC Trends in Analytical Chemistry」に掲載されました。 Internet

    大阪公立大学工学研究科  大阪公立大学工学研究科ウェブサイト  2023.01

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    SDGs:

  • 化学の“謎”の解明に向けてナノ流体デバイスが拓く溶液の単一分子反応ダイナミクス に関する総説論文を発表 Internet

    大阪公立大学  大阪公立大学ウェブサイト  2023.01

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    SDGs:

  • ナノ流体デバイスが拓く新しい化学 Promotional material

    日本分析化学会近畿支部  ぶんきんニュース  2022.08

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    SDGs:

  • 研究室だより:大阪公立大学 大学院工学研究科化学工学分野 ナノ化学システム工学グループ(許研究室) Promotional material

    電気学会論文誌E(センサ・マイクロマシン部門誌)  2022.05

  • Our paper (A biomimetic anti-biofouling coating in nanofluidic channels) recently published in Journal of Materials Chemistry B was selected as HOT Paper by the Editors as especially significant based on reviewers’ recommendations and their own appraisall Internet

    Journal of Materials Chemistry B  2022.01

  • OPU Professor’s Scientific Artwork Featured on the Cover of “Nano Letters” Internet

    大阪府立大学  大阪府立大学英語ウェブサイト  2021.12

  • 工学研究科 許 岩准教授らの論文が米国科学雑誌「Nano Letters」の表紙に採用 Internet

    大阪府立大学  大阪府立大学のウェブサイトおよびSNS  2021.12

  • ナノ流体デバイスによるナノスケールの超微小気液界面の作製に関する研究成果がNano Letters誌(2021年21巻24号)の表紙を飾りました Promotional material

    Nano Letters  2021.12

  • 大阪府立大学许岩课题组Nano Letters:纳米级可控气液界面 Internet

    化学と材料化学(中国のサイエンスメデイア)  2021.11

  • Yan Xu et al @OsakaPrefUniv , report the fabrication of nanoscale gas-liquid interfaces in a nanofluidic device, exhibiting capability to enrich molecules at a well-defined nanospace Internet

    Nano LettersのOfficial Twitter  2021.11

  • First controllable nanoscale gas-liquid interface fabricated Internet

    Chem Europe  2021.10

  • 研究成果が複数の英語のニュースサイトにてリリース、紹介、または転載されました Internet

    EurekAlert!, Asia Research News, Phys.org, Nanowerk, ScienMag, True Viral News, Mirage News, FUNTiTECH , Xnesnet, 等  First controllable nanoscale gas-liquid interface fabricated  2021.10

  • First Controllable Nanoscale Gas-liquid Interface Fabricated Internet

    大阪府立大学、大阪公立大学  英語ウェブサイト  2021.10

  • ナノスケールの超微小気液界面 大阪府大、高精度・均一に作製成功 Newspaper, magazine

    日刊工業新聞  2021.10

  • Fabrication of nanoscale gas-liquid interfaces in hydrophilic/hydrophobic nanopatterned nanofluidic channels Internet

    Youtube  2021.10

  • ナノスケールで物質の濃縮効果を発見―ナノ流体デバイスによる超微小気液界面の作製と効果―

    大阪府立大学とJST  共同プレスリリース  2021.10

  • 極微小ナノ流路構造体の作製方法に関する論文(Fabrication of Ultranarrow Nanochannels with Ultrasmall Nanocomponents in Glass Substrates)がMicromachines誌にEditor’s ChoiceとFeature Paperに選ばれた Promotional material

    Micromachines  2021.08

  • 一分子を操作するための超微小液滴の制御技術を開発 Promotional material

    日本分析化学会  日本分析化学会 第 68 年会展望とトピックス  2019.07

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Academic Activities

  • 日本分析化学会近畿支部幹事

    Role(s): Planning, management, etc.

    2019.04 - 2023.03

Foreigner acceptance

  • 2022

    foreigners accepted :3

International exchange activities

  • Naresuan University Secondary Demonstration Schoolの生徒と先生22人が大阪公立大学、工学研究科化学工学分野を訪問

    Field category :Education

    Country name :Thailand   2023.03

  • 国際共同研究加速基金(国際共同研究強化(B))の支援で、共同研究を行っています。

    Field category :Research

    Country name :USA、China   2022.04 - 2023.03