Updated on 2023/04/09

写真a

 
Matsumoto Takuya
 
Organization
Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology Assistant Professor
School of Engineering Department of Chemical Engineering
Title
Assistant Professor
Affiliation
Institute of Engineering
Affiliation campus
Nakamozu Campus

Position

  • Graduate School of Engineering Division of Science and Engineering for Materials, Chemistry and Biology 

    Assistant Professor  2022.04 - Now

  • School of Engineering Department of Chemical Engineering 

    Assistant Professor  2022.04 - Now

Degree

  • 博士(工学) ( Kobe University )

Research Areas

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Chemical reaction and process system engineering

  • Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering

  • Life Science / Applied microbiology

Research Interests

  • 反応工学

  • 微生物

  • 酵素

  • 生物化学工学

  • 合成生物学

  • 酵素工学

Research subject summary

  • 酵素を用いた物質変換技術に関する研究

  • 遺伝子組換え微生物を用いた有用物質生産に関する研究

Research Career

  • 大腸菌を用いた有用物質生産技術の開発

    Individual

    2018.04 - Now 

  • 酵母を用いた有用物質生産技術の開発

    Individual

    2018.04 - Now 

  • 酵素を用いた物質変換技術の開発

    Individual

    2018.04 - Now 

Professional Memberships

  • 極限環境生物学会

    2019.10 - Now   Domestic

  • 日本蛋白質科学会

    2019.02 - Now   Domestic

  • 酵素工学研究会

    2013.10 - Now   Domestic

  • 日本生物工学会

    2010.03 - Now   Domestic

  • 化学工学会

    2009.10 - Now   Domestic

Awards

  • 第7回新化学技術研究奨励賞

    2018.07   新化学技術推進協会  

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    Country:Japan

  • 21th Young Asian Biochemical Engineers Community ポスター賞

    2015.10   Asian Federation of Biotechnology  

  • 17th Young Asian Biochemical Engineers Community ポスター賞

    2011.10   Asian Federation of Biotechnology  

Job Career (off-campus)

  • 大阪公立大学   大学院工学研究科 物質化学生命系専攻 化学工学分野

    2022.04 - Now

  • Osaka Prefecture University

    2018.04 - 2022.03

Papers

  • Construction of a machine-learning model to predict the optimal gene expression level for efficient production of d-lactic acid in yeast

    Yamamoto Y.

    World Journal of Microbiology and Biotechnology   39 ( 3 )   69   2023.03( ISSN:09593993

  • Identification of genes responsible for absorbing palladium ion in Escherichia coli.

    Matsumoto T, Tanaka Y, Kamino M, Yamada R, Konishi Y, Ogino H

    Bioscience, biotechnology, and biochemistry   2023.02( ISSN:0916-8451

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  • Mevalonate production by electro-fermentation in Escherichia coli via Mtr-based electron transfer system

    Matsumoto T.

    Biochemical Engineering Journal   191   2023.02( ISSN:1369703X

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  • Promoting cell growth and characterizing partial symbiotic relationships in the co‐cultivation of green alga Chlamydomonas reinhardtii and Escherichia coli Reviewed

    Ryosuke Yamada , Moe Yokota , Takuya Matsumoto , Ben Hankamer , Hiroyasu Ogino

    Biotechnology Journal   18 ( 2 )   2200099   2022.12

  • Mitochondrial expression of metabolic enzymes for improving carotenoid production in Saccharomyces cerevisiae

    Takuya Matsumoto, Tomoki Osawa, Hikaru Taniguchi, Akira Saito, Ryosuke Yamada, Hiroyasu Ogino

    Biochemical Engineering Journal   189   108720 - 108720   2022.12( ISSN:1369-703X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bej.2022.108720

  • Protein engineering to improve the stability of Thermomyces lanuginosus lipase in methanol

    Taiki Okamura, Yohei Nogami, Takuya Matsumoto, Ryosuke Yamada, Hiroyasu Ogino

    Biochemical Engineering Journal   187   108659 - 108659   2022.11( ISSN:1369-703X

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bej.2022.108659

  • Bioengineering for the industrial production of 2,3-butanediol by the yeast, Saccharomyces cerevisiae.

    Ryosuke Mitsui, Ryosuke Yamada, Takuya Matsumoto, Hiroyasu Ogino

    World journal of microbiology & biotechnology   38 ( 3 )   38 - 38   2022.01

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    Publishing type:Research paper (scientific journal)   International / domestic magazine:International journal  

    Owing to issues, such as the depletion of petroleum resources and price instability, the development of biorefinery related technologies that produce fuels, electric power, chemical substances, among others, from renewable resources is being actively promoted. 2,3-Butanediol (2,3-BDO) is a key compound that can be used to produce various chemical substances. In recent years, 2,3-BDO production using biological processes has attracted extensive attention for achieving a sustainable society through the production of useful compounds from renewable resources. With the development of genetic engineering, metabolic engineering, synthetic biology, and other research field, studies on 2,3-BDO production by the yeast, Saccharomyces cerevisiae, which is safe and can be fabricated using an established industrial-scale cultivation technology, have been actively conducted. In this review, we sought to describe 2,3-BDO and its derivatives; discuss 2,3-BDO production by microorganisms, in particular S. cerevisiae, whose research and development has made remarkable progress; describe a method for separating and recovering 2,3-BDO from a microbial culture medium; and propose future prospects for the industrial production of 2,3-BDO by microorganisms.

    DOI: 10.1007/s11274-021-03224-x

    PubMed

  • Improving carotenoid production in recombinant yeast, Saccharomyces cerevisiae, using ultrasound-irradiated two-phase extractive fermentation Reviewed

    R. Yamada, Y. Ando, R. Mitsui, A. Mizobata, S. Yoshihara, H. Tokumoto, T. Matsumoto, H. Ogino

    Engineering in Life Sciences 雑誌   2022.01

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    Kind of work:Joint Work  

  • The synthesis of L-glycyl-L-tyrosine derivatives using organic-solvent stable PST-01 protease from Pseudomonas aeruginosa PST-01 Reviewed

    T. Matsumoto, R. Kitayama, R. Yamada, H. Ogino

    Process Biochemistry   2021.03

  • Improvement of 2,3-butanediol tolerance in Saccharomyces cerevisiae by using a novel mutagenesis strategy Reviewed

    A. Mizobata, R. Mitsui, R. Yamada, T. Matsumoto, S. Yoshihara, H. Tokumoto, H. Ogino

    Journal of Bioscience and Bioengineering 雑誌   2021.03

  • Improvement of lactic acid tolerance by cocktail δ-integration strategy and identification of the transcription factor PDR3 responsible for lactic acid tolerance in yeast Saccharomyces cerevisiae

    R. Yamada, Y. Kumata, R. Mitsui, T. Matsumoto, H. Ogino

    Journal of Microbiology and Biotechnology 雑誌   2021.01

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    Kind of work:Joint Work  

  • Identification of genes responsible for reducing palladium ion in Escherichia coli Reviewed

    T Matsumoto, M Kamino, R Yamada, Y Konishi, H Ogino

    Journal of Biotechnology 著書   2020.12

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    Kind of work:Joint Work  

  • Construction of lactic acid-tolerant Saccharomyces cerevisiae by using CRISPR-Cas-mediated genome evolution for efficient D-lactic acid production Reviewed

    R Mitsui, R Yamada, T Matsumoto, S Yoshihara, H Tokumoto, H Ogino

    Applied Microbiology and Biotechnology 雑誌   2020.11

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    Kind of work:Joint Work  

  • Construction of yeast producing patchoulol by global metabolic engineering strategy Reviewed

    R Mitsui, R Nishikawa, R Yamada, T Matsumoto, H Ogino

    Biotechnology and Bioengineerin 雑誌   2020.05

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    Kind of work:Joint Work  

  • Metabolic engineering of E. coli for improving mevalonate production to promote NADPH regeneration and enhance acetyl‐CoA supply Reviewed

    Daichi Satowa, Ryosuke Fujiwara, Shogo Uchio, Mariko Nakano, Chisako Otomo, Yuuki Hirata, Takuya Matsumoto, Shuhei Noda, Tsutomu Tanaka, Akihiko Kondo

    Biotechnology and Bioengineering 雑誌   2020.04

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    Kind of work:Joint Work  

  • N-linked glycosylation of thermostable lipase from Bacillus thermocatenulatus to improve organic solvent stability Reviewed

    S Kajiwara, R Yamada, T Matsumoto, H Ogino

    Enzyme and microbial technology 雑誌   2020.01

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    Kind of work:Joint Work  

  • n-Butylamine production from glucose using a transaminase-mediated synthetic pathway in Escherichia coli. Reviewed

    T. Matsumoto, Y. Mori, T. Tanaka*, A. Kondo

    Journal of Bioscience and Bioengineering 雑誌   2019.06

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    Kind of work:Joint Work  

  • Modification of lipase from Candida cylindracea with dextran using the borane-pyridine complex to improve organic solvent stability Reviewed

    Shota Kajiwara, Kyohei Komatsu, Ryosuke Yamada, Takuya Matsumoto, Masahiro Yasuda, Hiroyasu Ogino

    Journal of biotechnology 雑誌   2019.04

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    Kind of work:Joint Work  

  • Improvement of the organic solvent stability of a commercial lipase by chemical modification with dextran Reviewed

    Shota Kajiwara, Kyohei Komatsu, Ryosuke Yamada, Takuya Matsumoto, Masahiro Yasuda, Hiroyasu Ogino

    Biochemical engineering journal 雑誌   2019.02

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    Kind of work:Joint Work  

  • Enhancing 3-hydroxypropionic acid production in combination with sugar supply engineering by cell surface-display and metabolic engineering of Schizosaccharomyces pombe Reviewed

    Seiya Takayama, Aiko Ozaki, Rie Konishi, Chisako Otomo, Mayumi Kishida, Yuuki Hirata, Takuya Matsumoto, Tsutomu Tanaka, Akihiko Kondo

    Microbial cell factories 雑誌   2018.12

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    Kind of work:Joint Work  

  • Streptavidin-hydrogel prepared by sortase A-assisted click chemistry for enzyme immobilization on an electrode Reviewed

    T Matsumoto, Y Isogawa, T Tanaka, A Kondo

    Biosensors and Bioelectronics 雑誌   99   56 - 61   2018.01

  • 1, 5-Diaminopentane production from xylooligosaccharides using metabolically engineered Corynebacterium glutamicum displaying beta-xylosidase on the cell surface Reviewed

    K Imao, R Konishi, M Kishida, Y Hirata, S Segawa, N Adachi, R Matsuura, Y Tsuge, T Matsumoto, T Tanaka, A Kondo

    Bioresource technology 雑誌   245   1684 - 1691   2017.12

  • Metabolic engineering of Schizosaccharomyces pombe via CRISPR-Cas9 genome editing for lactic acid production from glucose and cellobiose Reviewed

    A Ozaki, R Konishi, C Otomo, M Kishida, S Takayama, T Matsumoto, T Tanaka, A Kondo

    Metabolic engineering communications 雑誌   5   60 - 67   2017.12

  • Sortase A-Mediated Metabolic Enzyme Ligation in Escherichia coli Reviewed

    T Matsumoto, K Furuta, T Tanaka, A Kondo

    ACS synthetic biology 雑誌   5 ( 11 )   1284 - 1289   2016.10

  • Improvement of ectoine productivity by using sugar transporter-overexpressing Halomonas elongata Reviewed

    K Tanimura, T Matsumoto, H Nakayama, T Tanaka, A Kondo

    Enzyme and microbial technology 雑誌   89   63 - 68   2016.07

  • 2, 3-Butanediol production from cellobiose using exogenous beta-glucosidase-expressing Bacillus subtilis Reviewed

    K Tanimura, S Takashima, T Matsumoto, T Tanaka, A Kondo

    Applied microbiology and biotechnology 雑誌   100 ( 13 )   5781 - 5789   2016.07

  • Twigged streptavidin polymer as a scaffold for protein assembly Reviewed

    T Matsumoto, Y Isogawa, K Minamihata, T Tanaka, A Kondo

    Journal of biotechnology 雑誌   225   61 - 66   2016.05

  • Secretory production of tetrameric native full-length streptavidin with thermostability using Streptomyces lividans as a host Reviewed

    S Noda, T Matsumoto, T Tanaka, A Kondo

    Microbial cell factories 雑誌   14 ( 1 )   2015.12

  • C‐Terminal‐oriented Immobilization of Enzymes Using Sortase A‐mediated Technique Reviewed

    Y Hata, T Matsumoto, T Tanaka, A Kondo

    Macromolecular bioscience 雑誌   15 ( 10 )   1375 - 1380   2015.10

  • Multi-functional glycoside hydrolase: Blon_0625 from Bifidobacterium longum subsp. infantis ATCC 15697 Reviewed

    T Matsumoto, S Shimada, Y Hata, T Tanaka, A Kondo

    Enzyme and microbial technology 雑誌   68   10 - 14   2015.01

  • Two‐Stage Oxidation of Glucose by an Enzymatic Bioanode Reviewed

    T Matsumoto, S Shimada, K Yamamoto, T Tanaka, A Kondo

    Fuel Cells 雑誌   13 ( 6 )   960 - 964   2013.12

  • Starchy biomass-powered enzymatic biofuel cell based on amylases and glucose oxidase multi-immobilized bioanode Reviewed

    K Yamamoto, T Matsumoto, S Shimada, T Tanaka, A Kondo

    New biotechnology 雑誌   30 ( 5 )   531 - 535   2013.06

  • Site‐specific protein labeling with amine‐containing molecules using Lactobacillus plantarum sortase Reviewed

    T Matsumoto, R Takase, T Tanaka, H Fukuda, A Kondo

    Biotechnology journal 雑誌   7 ( 5 )   642 - 648   2012.05

  • Sortase A-catalyzed site-specific coimmobilization on microparticles via streptavidin Reviewed

    T Matsumoto, T Tanaka, A Kondo

    Langmuir 雑誌   28 ( 7 )   3553 - 3557   2012.02

  • Site-specific tetrameric streptavidin-protein conjugation using sortase A Reviewed

    T Matsumoto, S Sawamoto, T Sakamoto, T Tanaka, H Fukuda, A Kondo

    Journal of biotechnology 雑誌   152 ( 1-2 )   37 - 42   2011.03

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Books and Other Publications

  • Sortase A-Assisted Metabolic Enzyme Ligation in Escherichia coli for Enhancing Metabolic Flux.

    Takuya MATSUMOTO, Tsutomu TANAKA, Akihiko KONDO( Role: Joint author)

    Synthetic Biology, Methods in Molecular Biology, Humana Press, New York  2018.05 

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    Responsible for pages:1772. 125-136  

  • Sortase Aを用いたタンパク質配向固定化技術の開発

    松本 拓也、田中 勉( Role: Joint author)

    シーエムシー出版   2018.04 

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    Responsible for pages:第3章  

MISC

  • ポリエチレンテレフタレート(PET)は生分解性?

    松本拓也

    日本生物工学会 バイオミディア   98 ( 2 )   2020.02

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  • Chemical treatments for modification and immobilization to improve the solvent-stability of lipase Reviewed

    T Matsumoto, R Yamada, H Ogino

    World Journal of Microbiology and Biotechnology   2019.12

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  • Engineering metabolic pathways in Escherichia coli for constructing a “microbial chassis” for biochemical production Reviewed

    T Matsumoto, T Tanaka, A Kondo

    Bioresource technology   245   1362 - 1368   2017.12

  • Enzyme‐mediated methodologies for protein modification and bioconjugate synthesis Reviewed

    T Matsumoto, T Tanaka, A Kondo

    Biotechnology journal   7 ( 9 )   1137 - 1146   2012.09

Presentations

  • PETaseを細胞表層に提示した大腸菌の開発

    山下 拓真, 松本 拓也, 山田 亮祐, 荻野 博康

    化学工学会第88年会  2023.03 

  • 複数遺伝子の同時発現抑制による酵母のβ-カロテン生産性向上

    山本 千尋, 三ツ井 良輔, 山田 亮祐, 坂口 瑠美, 松本 拓也, 荻野 博康

    化学工学会第88年会  2023.03 

  • 基質特異性の異なるThermomyces lanuginosus lipaseライブラリの作製

    森岡 りな, 野上 洋平, 松本 拓也, 山田 亮祐, 荻野 博康

    化学工学会第88年会  2023.03 

  • アシルキャリヤータンパク質の高発現によるアルカンの生成に優れた大腸菌の開発

    松原 武輝, 韓 佳虎, 浅野 紘輝, 松本 拓也, 山田 亮祐, 荻野 博康

    第25回化学工学会学生発表会  2023.03 

  • 酵母による高効率D-乳酸生産を目指した機械学習モデルの構築

    山本 祥輝, 山田 亮祐, 松本 拓也, 荻野 博康

    第74回日本生物工学会大会  2022.10 

  • Thermomyces lanuginosus由来のリパーゼへのメタノール耐性付与

    岡村 大毅, 野上 洋平, 松本 拓也, 山田 亮祐, 荻野 博康

    第24回化学工学会学生発表会  2022.03 

  • 有機溶媒耐性PST-01プロテアーゼを用いたアラニルアラニンの合成 Domestic conference

    水野ひなた,松本拓也,山田亮祐,冨田健一,星野美奈子,荻野博康

    化学工学会関西大会2021  2021.12 

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    Presentation type:Poster presentation  

  • 白金イオンの還元および吸着に関する大腸菌の遺伝子の探索 Domestic conference

    鬼頭和也,松本拓也,山田亮祐,荻野博康

    化学工学会関西大会2021  2021.12 

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    Presentation type:Poster presentation  

  • 酵母を用いた酵素のミトコンドリア局在化による3-ヒドロキシプロピオン酸の生産 Domestic conference

    大谷孝,松本拓也,山田亮祐,荻野博康

    化学工学会関西大会2021  2021.12 

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    Presentation type:Poster presentation  

  • 大腸菌の代謝改変によるバイオアルカンの生産性向上 Domestic conference

    浅野紘輝,松本拓也,山田亮祐,荻野博康

    化学工学会関西大会2021  2021.12 

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    Presentation type:Poster presentation  

  • 点変異・構造変異同時導入によるカロテノイド高生産酵母の創製 Domestic conference

    安藤和哉,山田亮祐,松本拓也,荻野博康

    化学工学会関西大会2021  2021.12 

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    Presentation type:Poster presentation  

  • 枯草菌との共培養による緑藻の増殖能の向上 Domestic conference

    大山遥行,山田亮祐,松本拓也,荻野 博康

    化学工学会関西大会2021  2021.12 

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    Presentation type:Poster presentation  

  • Transcriptome analysis of thermotolerant yeast mutant International conference

    R. Mitsui, R. Yamada*, T. Matsumoto, S. Yoshihara, H. Tokumoto, H. Ogino

    The 26th Symposium of Young Asian Biological Engineers’ Community  2021.11 

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    Presentation type:Oral presentation (invited, special)  

  • 点変異・構造変異同時導入による酵母の過酸化水素耐性およびカロテノイド生産性向上 Domestic conference

    安藤和哉,山田亮祐,松本拓也,荻野博康

    極限環境生物学会2021年度(第22回)年会  2021.11 

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    Presentation type:Poster presentation  

  • 緑藻と枯草菌との共培養による増殖特性の変化 Domestic conference

    大山遥行,山田亮祐,松本拓也,荻野博康

    第73回日本生物工学会大会  2021.10 

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    Presentation type:Poster presentation  

  • バイオアルカンの生産性改善を指向した大腸菌の代謝改変 Domestic conference

    浅野紘輝,松本拓也,山田亮祐,荻野博康

    化学工学会第52回秋季大会  2021.09 

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    Presentation type:Poster presentation  

  • 大腸菌によるレアメタルイオンの還元および吸着に関する遺伝子の探索 Domestic conference

    鬼頭和也,松本拓也,山田亮祐,荻野博康

    化学工学会第86年会  2021.03 

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    Presentation type:Poster presentation  

  • 酵母を用いた酵素のミトコンドリア局在化による有用物質生産 Domestic conference

    大谷孝,松本拓也,山田亮祐,荻野博康

    化学工学会第86年会  2021.03 

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    Presentation type:Poster presentation  

  • Construction and analysis of engineered D-lactic acid tolerant Saccharomyces cerevisiae

    三ツ井良輔, 山田亮祐, 松本拓也, 荻野博康

    18th Asian Pacific Confederation of Chemical Engineering Congress  2019.09 

  • Production of bioalkanes using engineered Escherichia coli

    濱志緒里, 松本拓也, 山田亮祐, 荻野博康

    18th Asian Pacific Confederation of Chemical Engineering Congress  2019.09 

  • Modulation of the mevalonate pathway in yeast for efficient patchoulol production by global metabolic engineering

    山田亮祐, 西川利留, 三ツ井良輔, 松本拓也, 荻野博康

    18th Asian Pacific Confederation of Chemical Engineering Congress  2019.09 

  • Improvement of 2,3-butandiol tolerance in yeast by a novel mutagenesis strategy

    溝端明日香, 三ツ井良輔, 山田亮祐, 松本拓也, 荻野博康

    18th Asian Pacific Confederation of Chemical Engineering Congress  2019.09 

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Collaborative research (seeds) keywords

  • 酵素を用いた物質変換技術に関する研究

  • 遺伝子組換え微生物を用いた有用物質生産に関する研究

  • ペプチド転移酵素を使ったタンパク質修飾技術

  • 微生物を用いた電気培養システム

Outline of collaborative research (seeds)

  • 酵素を用いた物質変換技術に関する研究

  • 遺伝子組換え微生物を用いた有用物質生産に関する研究

  • ペプチド転移酵素を使ったタンパク質修飾技術

  • 微生物を用いた電気培養システム

Charge of on-campus class subject

  • ケミカルエンジニアリングプラクティス

    2022   Weekly class   Undergraduate

  • 化学工学実験I

    2022   Weekly class   Undergraduate

  • 物質化学生命系特別演習

    2022   Intensive lecture   Graduate school

  • 物質化学生命系特別演習第1

    2022   Intensive lecture   Graduate school

  • 物質化学生命系特別研究 (化学工学分野)

    2022   Intensive lecture   Graduate school

  • 物質化学生命系特別演習第2 (化学工学分野)

    2022   Intensive lecture   Graduate school

  • Chemical Engineering Practice

    2020   Practical Training  

  • 化学工学実験I

    2020   Practical Training  

  • 化学工学実験I

    2019   Practical Training  

  • ケミカルエンジニアリングプラクティス

    2019   Practical Training  

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Faculty development activities

  • 化学工学実験I指針書  2022

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    化学工学実験I指針書作成

  • ケミカルエンジニアリングプラクティス指針書  2022

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    ケミカルエンジニアリングプラクティス指針書作成

  • 化学工学実験I指針書  2021

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    化学工学実験I指針書作成

  • ケミカルエンジニアリングプラクティス指針書  2021

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    ケミカルエンジニアリングプラクティス指針書作成

  • 化学工学実験I指針書  2020

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    化学工学実験I指針書作成

  • ケミカルエンジニアリングプラクティス指針書  2020

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    ケミカルエンジニアリングプラクティス指針書 作成

  • ケミカルエンジニアリングプラクティス指針書作成  2019

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    ケミカルエンジニアリングプラクティス指針書

  • 化学工学実験I指針書  2019

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    化学工学実験I指針書作成

  • 化学工学実験II指針書  2018

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    化学工学実験II指針書作成

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