Updated on 2024/05/01

写真a

 
Yamagishi Norio
 
Organization
Graduate School of Veterinary Science Department of Veterinary Science Professor
School of Veterinary Science Department of Veterinary Science
Title
Professor
Affiliation
Institute of Veterinary Science

Position

  • Graduate School of Veterinary Science Department of Veterinary Science 

    Professor  2022.04 - Now

  • School of Veterinary Science Department of Veterinary Science 

    Professor  2022.04 - Now

Degree

  • 博士（獣医学） （ Gifu University ）

  • 学士（獣医学） （ Rakuno Gakuen University ）

Research Areas

  • Life Science / Animal production science

  • Life Science / Veterinary medical science

  • Life Science / Veterinary medical science

  • Life Science / Veterinary medical science

  • Life Science / Veterinary medical science

  • Life Science / Animal production science

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Research Interests

  • Bovine Medicine

  • 食用動物医学

  • 臨床獣医学

  • 獣医病態生理学

  • 希少飼育反芻動物

  • Bovine Medicine

  • 希少飼育反芻動物

Research subject summary

  • 動物疾患の早期生前診断に有用な血中バイオマーカーに関する研究

  • 牛のカルシウム代謝ならびに骨代謝性疾患に関する血液生化学的研究

Research Career

  • 乳牛の分娩前後の血中・乳中オステオプロテゲリン濃度と 診断マーカーとしての臨床応用

    Individual

    2018.04 - Now 

Professional Memberships

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Committee Memberships (off-campus)

  • 委員   日本獣医師会　令和3年度　獣医学術年次大会企画実行委員会  

    2021.04 - 2022.03 

  • 講師   日本獣医師会　令和3年度　獣医療提供体制整備推進総合対策事業  

    2021.04 - 2022.03 

  • 審査員   全国農業共済組合　令和3年度中堅獣医師講習会に係る研究発表会  

    2021.04 - 2022.03 

  • Editor (Internal Medicine)   The Journal of Veterinary Medical Science  

    2021.01 - Now 

Awards

  • 令和5年度日本産業動物獣医学会（近畿）優秀賞

    山岸則夫, 川島千帆, 石川真悟

    2023.10   近畿地区連合獣医師会   分娩乳牛における初乳中骨代謝マーカーと産次あるいは乳熱との関連性

  • 令和5年度日本産業動物獣医学会（近畿）優秀賞

    山岸則夫, 川島千帆, 石川真悟

    2023.10   近畿地区連合獣医師会   分娩乳牛における初乳中骨代謝マーカーと産次あるいは乳熱との関連性

  • 日本家畜臨床学会奨励賞

    森山友恵、後藤聡、都築直、川島秀平、近藤拓、山岸則夫

    2022.11   日本家畜臨床学会   貫通固定ピンキャスト(TPC)で治療した育成牛の橈尺骨骨折の 1 例

  • 日本産業動物獣医学会（近畿）奨励賞

    宇崎敬与、笹倉春美、髭白侑香、北山 篤、小西健治、中村善彦、柄 武志、山岸則夫、畠中みどり1）

    2022.11   日本獣医師会・獣医学術近畿地区学会   ホルスタイン種子牛にみられた異所性肺組織を伴う二分脊椎症の複合奇形

  • 日本家畜臨床学会奨励賞

    森山友恵, 後藤聡, 都築直, 川島秀平, 近藤拓, 山岸則夫

    2022.11   日本家畜臨床学会   貫通固定ピンキャスト(TPC)で治療した育成牛の橈尺骨骨折の 1 例

  • 日本産業動物獣医学会（近畿）奨励賞

    宇崎敬与, 笹倉春美, 髭白侑香, 北山 篤, 小西健治, 中村善彦, 柄 武志, 山岸則夫, 畠中みどり

    2022.11   日本獣医師会・獣医学術近畿地区学会   ホルスタイン種子牛にみられた異所性肺組織を伴う二分脊椎症の複合奇形

  • Commendation from the Japanese Society of Veterinary Clinics

    A. Goto, A. Chiba, T. Moriyama, K. IIno, N. Yamagishi

    2021.11   Three cases of Japanese Black steer with scrotal abscess due to surgical site infection after castration

  • 令和3年度 日本産業動物獣医学会（近畿）奨励賞

    2021.10   日本獣医師会・獣医学術近畿地区学会  

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    Country：Japan

  • 令和3年度日本産業動物獣医学会（近畿）奨励賞

    山岸則夫, 川島千帆

    2021.10   近畿地区連合獣医師会   乳牛の乾乳後期の血中骨代謝マーカー値による乳熱発症予測の可能性

  • 令和3年度 日本産業動物獣医学会（近畿）奨励賞

    2021.10   日本獣医師会・獣医学術近畿地区学会  

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    Country：Japan

  • 令和3年度日本産業動物獣医学会（近畿）奨励賞

    山岸則夫, 川島千帆

    2021.10   近畿地区連合獣医師会   乳牛の乾乳後期の血中骨代謝マーカー値による乳熱発症予測の可能性

  • JMVS優秀論文賞

    Maetani, A., Ohtani, M., Hatate, K., Matsumoto, K., Yamagishi, N.

    2019.09   日本獣医学会   Effect of dietary difructose anhydride (DFA) III supplementation on bone mineral density and calcium metabolism in late-lactation dairy cows

  • JMVS優秀論文賞

    Maetani, A, Ohtani, M, Hatate, K, Matsumoto, K, Yamagishi, N

    2019.09   日本獣医学会   Effect of dietary difructose anhydride (DFA) III supplementation on bone mineral density and calcium metabolism in late-lactation dairy cows

  • 日本産業動物獣医学会・北海道地区学会長賞

    1992.09   北海道獣医師会  

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    Country：Japan

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Job Career (off-campus)

  • Osaka Metropolitan University

    2022.04 - Now

  • Osaka Prefecture University

    2020.10 - 2022.03

  • 帯広畜産大学　教授

    2015.10 - 2020.09

  • Obihiro University of Agriculture and Veterinary Medicine

    2015.10 - 2020.09

  • 岐阜大学　教授（大学院連合獣医学研究科博士課程兼職）

    2008.02 - 2020.09

  • 岐阜大学大学院連合獣医学研究科 教授（兼任）

    2008.02 - 2020.09

  • 岩手大学　教授

    2008.02 - 2015.09

  • 岩手大学　助教授

    2005.06 - 2008.01

  • 帯広畜産大学　助教授

    2003.02 - 2005.05

  • 帯広畜産大学　助手

    1996.07 - 2003.01

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Papers

  • Serum metabolic profiling in pregnant Holstein cows 3 weeks prior to parturition using two-dimensional gas chromatography time-of-flight mass spectrometry.

    Ichizawa S, Uenoyama R, Kawashima C, Miyazaki M, Yamagishi N, Miyazaki T

    The Journal of veterinary medical science   2024.04（ ISSN:0916-7250 ）

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  • Effects of trastuzumab emtansine on canine urothelial carcinoma cells in vitro and in vivo.

    Sakai K, Kato D, Yoshinaka J, Takahashi Y, Ikeda N, Aoki S, Iguchi T, Ishikawa S, Yamagishi N, Shimamura S, Nakagawa T

    Veterinary and comparative oncology   2024.03（ ISSN:1476-5810 ）

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  • Case report: Measuring the Circulating Bone Metabolic Markers of Two Asian Elephant (<i>Elephas maximus</i>) Calves Around Weaning

    TAKEHANA Kazuya, ADACHI Mare, ISHIKAWA Shingo, YAMAGISHI Norio

    Japanese Journal of Zoo and Wildlife Medicine   28 ( 2 )   115 - 120   2023.09（ ISSN:13426133 ） （ eISSN:2185744X ）

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    <p>　We measured the serum activities of the bone-specific isoenzyme of alkaline phosphatase (ALP3) and tartrate-resistant acid phosphatase 5b (TRAP5b), as osteoblastic bone formation and osteoclastic bone resorption markers, respectively, in two zoo-managed Asian elephant calves during the 4-month period around weaning (2 months before and after weaning). The serum ALP3 and TRAP5b levels decreased after weaning; the levels were significantly higher in the pre-than post-weaning period. These results suggest that osteoblastic bone formation and osteoclastic bone resorption slowed after weaning. Breast milk feeding of Asian elephants may play a significant role in osteoblastic and osteoclastic bone metabolism during the growth period.</p>

    DOI： 10.5686/jjzwm.28.115

  • 症例報告　アジアゾウ(Elephas maximus)の子ゾウ2頭における離乳前後の血中骨代謝マーカー値(Case report: Measuring the Circulating Bone Metabolic Markers of Two Asian Elephant(Elephas maximus) Calves Around Weaning)

    竹鼻 一也, 安達 希, 石川 真悟, 山岸 則夫

    日本野生動物医学会誌   28 ( 2 )   115 - 120   2023.09（ ISSN:1342-6133 ）

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    アジアゾウの子ゾウ2頭の離乳前後4ヵ月における骨芽細胞マーカー[骨型アルカリホスファターゼ(ALP3)]および破骨細胞マーカー[酒石酸耐性酸ホスファターゼ5b(TRAP5b)]の活性値を測定した.両測定値は離乳後に有意に減少したことから,骨芽細胞による骨形成と破骨細胞による骨吸収の低下が示唆された。以上より,アジアゾウの母乳は成長期の骨代謝に重要な役割を持つことが推察された。(著者抄録)

  • 症例報告 アジアゾウ(Elephas maximus)の子ゾウ2頭における離乳前後の血中骨代謝マーカー値(Case report: Measuring the Circulating Bone Metabolic Markers of Two Asian Elephant(Elephas maximus) Calves Around Weaning)

    竹鼻 一也, 安達 希, 石川 真悟, 山岸 則夫

    日本野生動物医学会誌   28 ( 2 )   115 - 120   2023.09（ ISSN:1342-6133 ）

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    アジアゾウの子ゾウ2頭の離乳前後4ヵ月における骨芽細胞マーカー[骨型アルカリホスファターゼ(ALP3)]および破骨細胞マーカー[酒石酸耐性酸ホスファターゼ5b(TRAP5b)]の活性値を測定した.両測定値は離乳後に有意に減少したことから,骨芽細胞による骨形成と破骨細胞による骨吸収の低下が示唆された。以上より,アジアゾウの母乳は成長期の骨代謝に重要な役割を持つことが推察された。(著者抄録)

  • 動物園で管理したアジアゾウ(Elephas maximus)の血清クレアチニンキナーゼと乳酸脱水素酵素のアガロースゲル電気泳動のパターン(Agarose gel electrophoresis pattern of serum creatine kinase and lactate dehydrogenase isoenzymes in zoo-managed Asian elephants(Elephas maximus))

    Takehana Kazuya, Adachi Mare, Ishikawa Shingo, Yamagishi Norio

    The Journal of Veterinary Medical Science   85 ( 5 )   578 - 583   2023.05（ ISSN:0916-7250 ）

  • 動物園で管理したアジアゾウ(Elephas maximus)の血清クレアチニンキナーゼと乳酸脱水素酵素のアガロースゲル電気泳動のパターン(Agarose gel electrophoresis pattern of serum creatine kinase and lactate dehydrogenase isoenzymes in zoo-managed Asian elephants(Elephas maximus))

    Takehana Kazuya, Adachi Mare, Ishikawa Shingo, Yamagishi Norio

    The Journal of Veterinary Medical Science   85 ( 5 )   578 - 583   2023.05（ ISSN:0916-7250 ）

  • The serum activities of alkaline phosphatase isoenzymes measured using two approved methods in zoo-managed Asian elephants (Elephas maximus)

    Takehana K, Adachi M, Ishikawa S, Yamagishi N

    Journal of Veterinary Medical Science   85 ( 2 )   232 - 235   2023.02

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  • The serum activities of alkaline phosphatase isoenzymes measured using two approved methods in zoo-managed Asian elephants(Elephas maximus)(和訳中)

    Takehana Kazuya, Adachi Mare, Ishikawa Shingo, Yamagishi Norio

    The Journal of Veterinary Medical Science   85 ( 2 )   232 - 235   2023.02（ ISSN:0916-7250 ）

  • The serum activities of alkaline phosphatase isoenzymes measured using two approved methods in zoo-managed Asian elephants(Elephas maximus)(和訳中)

    Takehana Kazuya, Adachi Mare, Ishikawa Shingo, Yamagishi Norio

    The Journal of Veterinary Medical Science   85 ( 2 )   232 - 235   2023.02（ ISSN:0916-7250 ）

  • Agarose gel electrophoresis pattern of serum creatine kinase and lactate dehydrogenase isoenzymes in zoo-managed Asian elephants (<i>Elephas maximus</i>)

    TAKEHANA Kazuya, ADACHI Mare, ISHIKAWA Shingo, YAMAGISHI Norio

    Journal of Veterinary Medical Science   advpub ( 0 )   578 - 583   2023（ ISSN:09167250 ） （ eISSN:13477439 ）

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    Authorship：Last author,　Corresponding author  

    <p>Serum levels of creatine kinase (CK) and lactate dehydrogenase (LDH) isoenzymes were evaluated in nine zoo-managed Asian elephants (<i>Elephas maximus</i>) using a commercial agarose gel electrophoresis (AGE) kit. CK was separated into two major fractions, CK-BB and CK-MM, along with a small fraction of macroenzyme-CK type 2 (mCK2); CK-MM was the largest fraction. LDH was separated into five fractions (LDH1–5); LDH3 was the largest fraction. Age was negatively and positively correlated with the percentages of CK-BB and CK-MM, respectively, and negatively correlated with CK-BB and mCK2 activities. These results indicate that an AGE kit can be used to evaluate CK and LDH isoenzymes. Routine isoenzyme testing may enable early detection of disease and physiological changes.</p>

    DOI： 10.1292/jvms.22-0550

    PubMed

  • Prepartum measurement of serum biomarkers reflecting osteoclastic and osteoblastic bone metabolism for predicting the risk of milk fever in dairy cows.

    Norio Yamagishi, Chiho Kawashima

    The Journal of dairy research   1 - 9   2022.03（ ISSN:0022-0299 ）

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    Authorship：Lead author,　Corresponding author   Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    We investigated whether prepartum levels of serum bone biomarkers are related to the degree of parturient hypocalcaemia and risk of milk fever (MF) in dairy cows with advancing parity. A total of 58 late-pregnant cattle were assigned to four groups: nulliparous, primiparous, multiparous in the 2nd lactation and multiparous in the 3rd-5th lactation. The multiparous cows were further assigned to MF and non-MF groups according to the onset of MF. Serum samples were obtained from the cows during the 3 weeks prepartum to 5 d postpartum period for the measurement of serum calcium (Ca) and three bone biomarkers: tartrate-resistant acid phosphatase isoform 5b (TRAP5b), osteoprotegerin (OPG) and bone isoenzyme of alkaline phosphatase (ALP3). The ratios of OPG to TRAP5b (O/T ratio) and ALP3 to TRAP5b (A/T ratio) were calculated. The data from all cattle showed that the severity of hypocalcaemia at parturition increased with advancing parity/age. The MF cows had elevated serum TRAP5b activity and a decreased O/T ratio after parturition, suggesting an increased number of osteoclasts due to osteoclastogenesis, in response to severe hypocalcaemia. The MF cows showed lower serum ALP3 activity during the 3 weeks prepartum than the non-MF cows, therefore, prepartum osteoblast function was likely weak in the MF cows. During the 2-3 weeks prepartum, serum ALP3 activity and the A/T ratio had moderate associations with the serum Ca concentration at day 0 (day of calving) in the multiparous cows, and receiver operating characteristic curve analysis revealed that ALP3 activity had excellent ability to predict MF. In conclusion, prepartum serum ALP3 activity is a promising biomarker to predict MF in multiparous cows.

    DOI： 10.1017/S0022029922000218

    PubMed

  • The effects of maternal supplementation of rumen-protected lysine during the close-up dry period on newborn metabolism and growth in Holstein calves

    Chiho Kawashima, Hako Oie, Riku Mashimo, Akira Goto, Nobuyuki Kusaba, Norio Yamagishi

    Journal of Animal Physiology and Animal Nutrition   2022（ ISSN:0931-2439 ） （ eISSN:1439-0396 ）

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    Publishing type：Research paper (scientific journal)  

    This study aimed to evaluate the effects of rumen-protected lysine (RPL) supplementation during the close-up period on blood metabolites and calf growth. Forty multiparous Holstein dams were selected based on parity, body condition score, and expected calving date, and randomly assigned to a group: with RPL (n = 22) or without (control [CON], n = 18). RPL dams were supplied daily with 80 g of RPL from Day 21 before the expected calving date to parturition. Blood samples were obtained from the dams before the start of supplementation, 1 week before calving, and immediately after calving, and from calves immediately after birth and weekly until 8 weeks of age. Body weight measurements were performed immediately after birth in all calves and at weekly intervals until 8 weeks of age in female calves. No significant difference was observed in serum metabolite levels and plasma amino acid concentrations between the RPL and CON dams before supplementation, whereas plasma lysine concentrations tended to be higher in RPL dams immediately after calving (p = 0.07). Serum total protein levels (p < 0.05) were higher, whereas plasma total amino acid, total essential amino acid, total non-essential amino acid, and other amino acid concentrations were lower in the calves of RPL dams than those of CON dams (p < 0.05). There were no significant differences in calf birth weight between the two groups, although female calves of RPL dams (n = 7) had higher serum total protein (p < 0.05) and tended to have greater body weight (p = 0.09) from 1 to 8 weeks of age than those of CON dams (n = 11). Overall, RPL supplementation during the close-up period may increase placenta-mediated amino acid transfer to the foetus and enhance protein synthesis in the calf, leading to improved weight gain during the suckling period.

    DOI： 10.1111/jpn.13695

    PubMed

  • The serum activities of alkaline phosphatase isoenzymes measured using two approved methods in zoo-managed Asian elephants (<i>Elephas maximus</i>)

    TAKEHANA Kazuya, ADACHI Mare, ISHIKAWA Shingo, YAMAGISHI Norio

    Journal of Veterinary Medical Science   advpub ( 0 )   2022（ ISSN:09167250 ） （ eISSN:13477439 ）

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    Authorship：Last author,　Corresponding author  

    <p>The approved Japanese measurement method of circulating alkaline phosphatase (ALP) has changed from that of the Japan Society of Clinical Chemistry (JSCC) to that of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). We measured the serum levels of total ALP (t-ALP) and those of the isoenzymes ALP2 and ALP3 in 50 Asian elephant (<i>Elephas maximus</i>) specimens using both methods. The activities determined by the IFCC method were roughly one-third lower than those determined by the JSCC method. We present conversion formulae. Our results enable comparisons of historical and current data on serum ALP activities in endangered, zoo-managed Asian elephants.</p>

    DOI： 10.1292/jvms.22-0440

    PubMed

  • 貫通固定ピンキャスト(TPC)で治療したホルスタイン育成牛の橈尺骨骨折の1例

    森山 友恵, 後藤 聡, 都築 直, 川島 秀平, 近藤 拓, 山岸 則夫

    産業動物臨床医学雑誌   12 ( 2 )   78 - 84   2021.08（ ISSN:1884-684X ）

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    ホルスタイン種の雌育成牛(238日齢、体重247kg)における左橈尺骨骨幹の非開放性斜骨折と診断した症例について、貫通固定ピンとフルリムキャストを用いた貫通固定ピンキャスト(TPC)法による治療を行った。術中は塩酸キシラジンの静脈内投与(0.2mg/kg)で仰臥位保定後、塩酸メデトミジンの定量持続点滴(20μg/kg/hr)にて鎮静を維持し、2%リドカイン10mlによる腕神経叢ブロックで疼痛管理した。患肢の牽引と骨把持鉗子により骨折端を合わせて固定し、整形外科用パワードリルを用いて直径4.0mmの貫通固定ピンを、骨折端を挟む遠位および近位側橈骨骨幹にピンを各2本、近位および遠位骨の骨折端および骨折面を貫通するようにピン3本をそれぞれ貫通させた。さらにその上からフルリムキャストを巻き、キャスティングテープ表面から露出したピンは約4cmで切断し、即時重合レジンで各ピンの切断部を被覆・結合した。手術時間は80分であった。症例は覚醒後すぐに起立歩行可能であり同日中に退院、単房で個別飼育とし、術後1週間の抗生物質製剤投与を行った。術後48日目にX線所見にて明瞭な仮骨形成を認めたため、手根関節以下の遠位側のキャスティングテープ部分を切断・除去した。術後81日目にキシラジン鎮静下でTPC全てを除去し治癒とした。治療期間中および治療後の起立歩行は問題なく、その後の発育も順調であった。牛の橈骨骨折では内固定で高い治癒率が報告されているが治療にかかるコスト、手術時間および難易度、術後合併症のリスクにおいてTPCは内固定よりも生産動物である本症例にメリットを与えた。牛の骨折治療では体重が予後に影響を与え、さらにTPCでは使用する貫通固定ピンの太さ・本数・配置ならびにフレームであるキャストの長さが、骨折端の安定性や固定の強度に影響を与える。体重が重い個体の橈骨骨折をTPCにて治療した報告は限られており、本症例は今後の治療の際の良いモデルとなった。(著者抄録)

  • 乾乳牛へのペレット状グリセリン給与が分娩前後の栄養代謝状態および分娩後の疾病発生や乳量，繁殖機能回復へ及ぼす影響 Reviewed

    川島千帆, 近藤萌里, 長谷川類, 畔上正晴,大井樹里, 澁谷俊樹, 杉本優香, 山岸則夫

    日本畜産学会報 雑誌   92 ( 2 )   2021.07

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    Kind of work：Joint Work  

  • 乾乳牛へのペレット状グリセリン給与が分娩前後の栄養代謝状態および分娩後の疾病発生や乳量、繁殖機能回復へ及ぼす影響

    川島 千帆, 近藤 萌里, 長谷川 類, 畔上 正晴, 大井 樹里, 澁谷 俊樹, 杉本 優香, 山岸 則夫

    日本畜産学会報   92 ( 2 )   159 - 168   2021.05（ ISSN:1346-907X ）

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    乾乳牛へのペレット状グリセリン給与が分娩前後の栄養代謝状態と分娩後の疾病発生や生産性へ及ぼす影響を調査した。分娩予定3週前から分娩までグリセリン80g含有ペレット(Gly、20頭)またはプラセボペレット(Cnt、21頭)を毎日給与した。Cntのルーメンフィルスコアは分娩前に低下したが(P<0.05)、Glyで変化せず、分娩前の血中β-ヒドロキシ酪酸(BHBA)濃度はGlyで低かった(P<0.05)。分娩前後のボディコンディションスコア(BCS)はGlyで高かった(前;P<0.05、後;P=0.06)。ケトーシス発症頭数に差はないが治療牛の血中BHBA濃度はGlyで低い傾向にあった(P=0.07)。以上より、分娩予定3週前からのグリセリンペレット給与は給与中の採食量を一定に保ち脂質代謝を改善させ、分娩前後のBCSの適切な維持やケトーシスの症状を緩和させる可能性が示された。(著者抄録)

  • Nutritional parameters in the blood of dams during late gestation and immediately after calving, in the umbilical vein at calving, and in the blood of calves immediately following birth in Holstein heifers pregnant with either Holstein or beef breed fetuses.

    Chiho Kawashima, Sakura Kume, Norio Yamagishi

    Animal science journal = Nihon chikusan Gakkaiho   92 ( 1 )   e13555   2021.01（ ISSN:1344-3941 ） （ eISSN:1740-0929 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    Dairy cattle management lacks consideration of fetal breed, the effect of which on fetal growth and nutrition are unclear. We investigated blood parameters in 12 late-pregnant Holstein heifers with similar (Holstein, n = 5) or different (Japanese Black [n = 4] or F1 cross [n = 3]; Holstein × Japanese Black) fetus breeds and in their umbilical cords and calves. Samples were obtained from dams 1 week before calving (-1 week) and immediately after calving, from the umbilical vein at calving, and from calves immediately after birth. Dams with beef fetuses had higher serum glucose levels (-1 week; p < .05) than those with Holstein fetuses. Plasma total amino acid, total essential amino acid, total nonessential amino acid, and other amino acid concentrations were lower in the umbilical veins of dams with calves of the beef breeds than in those of the Holstein breeds (p < .05). Furthermore, serum glucose and plasma amino acid levels were lower in the beef calves than in the Holstein calves (p < .05). Overall, nutrient supply from dams to beef fetuses was lower than that to Holstein fetuses. Our findings may facilitate feeding management of dairy cattle pregnant with beef breeds for appropriate fetal growth and nutrition.

    DOI： 10.1111/asj.13555

    PubMed

  • Consecutive changes in serum alkaline phosphatase isoenzyme 3 activities in Holstein heifers during the first 18 months of life. Reviewed

    Akiko Chiba, Kaoru Hatate, Rurika Onomi, Chiho Kawashima, Masaaki Hanada, Tomoe Moriyama, Akira Goto, Norio Yamagishi

    The Journal of veterinary medical science   82 ( 11 )   1643 - 1647   2020.12（ ISSN:0916-7250 ） （ eISSN:1347-7439 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：Domestic journal  

    This study investigated consecutive fluctuations in serum activities of bone-specific alkaline phosphatase (ALP) isoenzyme 3 (ALP3) in 11 clinically healthy Holstein heifers during the first 18 months of life. ALP3 activities at the first sampling time point after weaning (3 months) were significantly lower than those at multiple time points during the pre-weaning period. Those activities increased from a minimum at 3 months to a peak at 6 months during the post-weaning period. In the anthropometric data, daily body weight and wither height gains appeared to be below the public data at 4 months and 4-5 months, respectively. The data suggested that serum ALP3 activity can be used to monitor skeletal growth of heifers at weaning.

    DOI： 10.1292/jvms.20-0306

    PubMed

  • 18月齢までのホルスタイン未経産牛における血清中アルカリフォスファターゼアイソザイム3活性の連続変化(Consecutive changes in serum alkaline phosphatase isoenzyme 3 activities in Holstein heifers during the first 18 months of life)

    Chiba Akiko, Hatate Kaoru, Onomi Rurika, Kawashima Chiho, Hanada Masaaki, Moriyama Tomoe, Goto Akira, Yamagishi Norio

    The Journal of Veterinary Medical Science   82 ( 11 )   1643 - 1647   2020.11（ ISSN:0916-7250 ）

  • Peripartum changes in serum activities of three major alkaline phosphatase isoenzymes in Holstein dairy cows Reviewed

    Chiba, A., Onomi, R., Hatate, K., Moriyama, T., Goto, A., Yamagishi, N.

    Polish Journal of Veterinary Science 雑誌   23 ( 3 )   2020.10

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    Kind of work：Joint Work  

    Repository URL： http://hdl.handle.net/10466/00017198

  • Peripartum changes in serum activities of three major alkaline phosphatase isoenzymes in Holstein dairy cows.

    A Chiba, R Onomi, K Hatate, T Moriyama, A Goto, N Yamagishi

    Polish journal of veterinary sciences   23 ( 3 )   457 - 459   2020.09（ ISSN:1505-1773 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    This study investigated changes in serum levels of hepatic, bone, and intestinal alkaline phosphatase (ALP) isoenzymes (ALP2, ALP3, and ALP5, respectively) in Holstein cows around parturition. Tartrate-resistant acid phosphatase 5b (TRAP5b) activity and calcium (Ca) concen-trations were also measured. We analyzed blood samples from 11 late-pregnant heifers (primipa-rous group) and 13 multiparous (2-4 lactations; multiparous group) cows at 3 weeks (18-24 days prepartum; -3 weeks), 2 weeks (17-11 days prepartum; -2 weeks), and 1 week (10-4 days prepar-tum; -1 weeks) before parturition; the day of calving (within 12 h post-calving; day 0); and 5 days postpartum (5 days). ALP3 activity was significantly higher in the primiparous group than in the multiparous group, whereas the activities decreased significantly in both groups after 5 days. ALP2 and ALP5 activities did not change, whereas ALP2 activity was significantly higher in the primiparous group than in the multiparous group. TRAP5b activity was significantly higher in the primiparous group than in the multiparous group and showed a transient significant increase at day 0. Ca concentration significantly decreased at day 0 in both groups; the Ca level at day 0 was significantly higher in the primiparous group than in the multiparous group. These data show that ALP3 activity in serum may indicate a change in osteoblastic bone forma-tion after calving, but further study is needed to determine the clinical application for measuring ALP isoenzymes in bovine medicine.

    DOI： 10.24425/pjvs.2020.134691

    PubMed

  • Blood markers of osteoclastic differentiation in periparturient dairy cows at different parities, with and without milk fever.

    Kaoru Hatate, Chiho Kawashima, Mitsunori Kayano, Masaaki Hanada, Norio Yamagishi

    Research in veterinary science   131   301 - 305   2020.08（ ISSN:0034-5288 ） （ eISSN:1532-2661 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    Osteoprotegerin (OPG) inhibits osteoclast (OC) differentiation. TRAP5b (tartrate-resistant acid phosphatase 5b) secreted by OCs reflects the numbers of mature OCs. This study assessed these OC-related markers around parturition in cows of different parities and in cows with milk fever (MF). The blood OPG and TRAP5b concentrations, as well as the ratio of OPG to TRAP5b (O/T), were measured beginning 3 weeks before (-21 d) and over a few days after calving in 49 Holstein Friesian cows at first (n = 8), second (n = 17), third (n = 12), and fourth or greater (n = 12) parities. The ratio of O/T at -21 d to O/T at calving (PreCOT) was also calculated. In the third and greater parities, seven cows developed MF (non-MF, n = 17). Regardless of the development of MF, the serum OPG started to decline in the last week of gestation only in the cows entering the second lactation, while the blood TRAP5b increased at calving in all cows. O/T decreased toward parturition only in multiparous cows. The decrease in O/T at caving was less pronounced in MF cows. PreCOT was negatively correlated with lactation number only in multiparous cows (n = 41, ρ = -0.50, P < .01). This study implied that OC differentiation toward calving was tapered in cows with advanced parities, and these indexes predict the risk of MF.

    DOI： 10.1016/j.rvsc.2020.05.009

    PubMed

  • 観血去勢後の手術部位感染により陰嚢膿瘍を形成した黒毛和種去勢牛の3例

    後藤 聡, 千葉 暁子, 森山 友恵, 飯野 君枝, 山岸 則夫

    産業動物臨床医学雑誌   11 ( 2 )   82 - 86   2020.08（ ISSN:1884-684X ）

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    国内の肉牛生産現場において、去勢は最も頻繁に行われる外科処置の1つである。去勢は生産性向上の観点から畜産現場で広く実施され、なかでも観血法による精巣摘出が主流とされている。今回、観血去勢後の手術部位感染(surgical site infection:SSI)により陰嚢膿瘍を形成した黒毛和種去勢牛3頭に対して、一般身体検査および超音波診断装置を用いて陰嚢や精索の形状、膿様物の有無を精査した後、外科的治療を行った。局所的な陰嚢膿瘍と診断した2例において、膿瘍は非感染部との境界が明瞭であったことから陰嚢の全切除を行った。1例において精索は膿瘍として大きく腫大したまま腹腔内深部へと連絡していたことから、陰嚢切除ならびに精索瘻による腹腔内膿瘍の排膿処置を行った。術後には継続的な精索瘻の内腔の洗浄を行い、精索の大きさは退縮、排膿の量も減少、手術後42日目には精索瘻の炎症消退と創傷収縮を認めた。いずれの症例も治癒転帰となったことから、陰嚢切除ならびに精索瘻による腹腔内膿瘍の排膿は有効な治療法であったと考えられた。今回の3例は、獣医師ならびに畜産関係者に対して、簡易外科手技である去勢術の衛生的な手技実施ならびにSSI予防対策に努めることの必要を再認識させる重要な症例であった。(著者抄録)

  • Anthropometric and blood data on a hand-reared captive Asian elephant (Elephas maximus) calf: A retrospective case report.

    Kazuya Takehana, Ryohei Kitani, Kaoru Hatate, Rurika Onomi, Norio Yamagishi

    The Journal of veterinary medical science   82 ( 7 )   943 - 947   2020.07（ ISSN:0916-7250 ） （ eISSN:1347-7439 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：Domestic journal  

    The anthropometric and blood data of an unsuccessfully hand-reared Asian elephant (Elephas maximus) calf were retrospectively compared with the data for calves raised by their real mothers or allomothers, to identify potential reasons for poor outcomes in the hand-reared case. The hand-reared calf grew normally in terms of body weight and withers height. However, blood biochemical data suggested reduced bone metabolism, low immune status, and malnutrition during its life. Blood bone markers were measured to determine whether a skeletal disorder was present in the Asian elephant calf, which was not clear from the anthropometric data. Monitoring these parameters in hand-reared Asian elephant calves, with the aim of keeping them within the normal range, may increase the success rate of hand-rearing of Asian elephant calves.

    DOI： 10.1292/jvms.19-0666

    PubMed

  • Anthropometric and blood data of a hand-reared captive Asian elephant (Elephas maximus) calf: a retrospective case report Reviewed

    108. Takehana, K., Kitani, R., Hatate, K., Onomi, R., Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   82   2020.07

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    Kind of work：Joint Work  

  • 人工飼育のアジアゾウ(Elephas maximus)幼獣の身体計測データと血液データ　後ろ向き症例検討(Anthropometric and blood data on a hand-reared captive Asian elephant(Elephas maximus) calf: A retrospective case report)

    Takehana Kazuya, Kitani Ryohei, Hatate Kaoru, Onomi Rurika, Yamagishi Norio

    The Journal of Veterinary Medical Science   82 ( 7 )   943 - 947   2020.07（ ISSN:0916-7250 ）

  • Agarose gel electrophoretic pattern of serum alkaline phosphatase isoenzymes in Holstein cows during lactation Reviewed

    Chiba, A., Hatate, K., Onomi, R., Moriyama, T., Goto, A., Yamagishi, N.

    Polish Journal of Veterinary Science 雑誌   23 ( 2 )   2020.06

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    Kind of work：Joint Work  

  • 日本の重ばん馬における初乳と仔馬の血清免疫グロブリンG濃度と周産期における異常との関連性(Colostral and foal serum immunoglobulin G levels and associations with perinatal abnormalities in heavy draft horses in Japan)

    Aoki Takahiro, Chiba Akiko, Itoh Megumi, Nambo Yasuo, Yamagishi Norio, Shibano Ken-ichi, Cheong Soon Hon

    Journal of Equine Science   31 ( 2 )   29 - 34   2020.06（ ISSN:1340-3516 ）

  • Colostral and foal serum immunoglobulin G levels and associations with perinatal abnormalities in heavy draft horses in Japan. Reviewed

    Takahiro Aoki, Akiko Chiba, Megumi Itoh, Yasuo Nambo, Norio Yamagishi, Ken-Ichi Shibano, Soon Hon Cheong

    Journal of equine science   31 ( 2 )   29 - 34   2020.06（ ISSN:1340-3516 ） （ eISSN:1347-7501 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：Domestic journal  

    The purpose of this study was to elucidate the colostral and foal serum immunoglobulin G (IgG) concentration values in heavy draft horses in Japan and to examine the effects of peripartum mare condition on colostral immunity. Colostrum was obtained 1 hr after foaling (pre-suckling; n=178). Blood was collected from the jugular vein of the foals (n=147) at 24 to 48 hr after birth. The foaling statuses of 73 mares were recorded. The average colostral IgG concentration was 10,540 ± 3,190 mg/dl (median=10,928; range 1,434-17,514 mg/dl). The average serum IgG concentration obtained from neonatal foals 24 to 48 hr after birth was 1,750 ± 919 mg/dl (median=1,890; range 0-3,510 mg/dl). Although colostral IgG did not differ between the normal foaling mare (n=59) and dystocial mare (n=14), foal serum IgG was lower in foals born in dystocia than in foals in normal foaling (P<0.05). This study demonstrates reference values for colostral and foal serum IgG specific to heavy draft horses in Japan and suggests that dystocia may interfere with the acquisition of colostral immunity in neonatal foals.

    DOI： 10.1294/jes.31.29

    PubMed

  • Agarose gel electrophoresis pattern of serum alkaline phosphatase isoenzymes in Holstein cows during lactation.

    A Chiba, K Hatate, R Onomi, T Moriyama, A Goto, N Yamagishi

    Polish journal of veterinary sciences   23 ( 2 )   317 - 319   2020.06（ ISSN:1505-1773 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    A recent study found that an agarose gel electrophoresis (AGE) method yielded two distinct major bands corresponding to the hepatic and bone ALP isoenzymes (ALP2 and ALP3, respec-tively) in bovine serum treated with protease and neuraminidase (PN-treatment), although there were concerns that the intestinal ALP isoenzyme (ALP5) often overlapped with ALP3 in human serum treated with neuraminidase. Because ALP5 was separated from ALP3 in bovine serum treated with protease alone (P-treatment), we used a modified method employing both P- and PN-treated bovine sera to measure the activities of the three ALP isoenzymes in 53 lacta-ting Holstein cows: 24 primiparous and 29 multiparous. Upon electrophoresis, 51 of 53 samples (96.2%) subjected to P-treatment yielded a distinct fraction corresponding to ALP5, as did the control serum. All PN-treated sera yielded a definite ALP2 fraction. The ALP3 fraction was calculated as the remainder after excluding ALP2 and ALP5. The activities of total ALP (t-ALP) and ALP3 in primiparous cows were higher than those in multiparous cows (p ⟨ 0.001) at early-to-peak [10-110 days in milk (DIM)] and mid (111-220 DIM) lactation. In the multi-parous cows, the ALP3 activity at late lactation (221-477 DIM) was significantly higher than that at early-to-peak lactation. Thus, the modified AGE method described here is able to discrimi-nate three fractions of ALP isoenzymes in the sera of lactating cows. The AGE pattern of circu-lating ALP isoenzymes will contribute to the understanding of the physiological bone metabolism status in lactating cows.

    DOI： 10.24425/pjvs.2020.133648

    PubMed

  • Intestinal ganglioneuroma in a neonatal Japanese black calf - Short communication.

    Jun Sasaki, Yusuke Kuroda, Atsushi Ueki, Bhuminand Devkota, Norio Yamagishi

    Acta veterinaria Hungarica   68 ( 1 )   49 - 52   2020.03（ ISSN:0236-6290 ） （ eISSN:1588-2705 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    A 1-day-old male calf presented with clinical signs of severe progressive abdominal distension. Abdominal radiographic and ultrasonic images revealed several loop-like structures in the small intestine, which were indicative of gas retention. Experimental laparotomy was performed. However, the calf died during surgery. At necropsy, a round, well-circumscribed mass (3 × 3 × 2.5 cm) was found in the jejunal wall, and the jejunal lumen was narrowed. The mass was firm and had white to grey appearance on the cut surface. Histologically, the submucosa and the muscle layer were diffusely thickened due to abundance of neural tissues comprising several fascicles of nerve fibres and large aggregates of ganglion cells. Some ganglion cells contained basophilic Nissl substances in their cytoplasm. Immunohistochemically, these cells were positive for S-100 and synaptophysin. Ultrastructural examination revealed that the neoplastic ganglion cells contained dense core vesicles in the cytoplasm. Based on these findings, the neoplastic lesion was diagnosed as ganglioneuroma in the jejunum.

    DOI： 10.1556/004.2020.00012

    PubMed

  • Colostral and foal serum immunoglobulin G levels and associations with perinatal abnormalities in heavy draft horses in Japan Reviewed

    Aoki, T., Chiba, A., Itoh, M., Nambo, Y., Yamagishi, N., Shibano, K. and Cheong, S. H

    Journal of Equine Science 雑誌   31 ( 2 )   2020.01

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    Kind of work：Joint Work  

  • Gene expression profiles in bovine granulocytes reflect the aberration of liver functions Reviewed

    Kizaki, K., Kato-Kageyama, T., Toji, N., Koshi, K., Sasaki, K., Yamagishi, N., Ishiguro-Oonuma, T., Takahashi, T., Hashizume, K.

    Animal Science Journal 雑誌   91 ( 1 )   2020.01

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    Kind of work：Joint Work  

  • Intestinal ganglioneuroma in a neonatal Japanese Black calf – Short communication Reviewed

    Sasaki, J., Kuroda, T., Ueki, A., Devkota, B., Yamagishi, N.

    Acta Veterinaria Hungarica 雑誌   68 ( 1 )   2020.01

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    Kind of work：Joint Work  

  • Blood markers of osteoclastic differentiation in parturient dairy cows at different parities, with and without milk fever Reviewed

    Hatate, K., Kawashima, C., Kayano, M., Hanada, M., Yamagishi, N.

    Research in Veterinary Science 雑誌   131   2020.01

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    Kind of work：Joint Work  

  • Gene expression profiles in bovine granulocytes reflect the aberration of liver functions

    Keiichiro Kizaki, Tomomi Kageyama, Noriyuki Toji, Katsuo Koshi, Kouya Sasaki, Norio Yamagishi, Toshina Ishiguro-Oonuma, Toru Takahashi, Kazuyoshi Hashizume

    ANIMAL SCIENCE JOURNAL   91 ( 1 )   e13324   2020.01（ ISSN:1344-3941 ） （ eISSN:1740-0929 ）

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    Publishing type：Research paper (scientific journal)  

    Liver performs several important functions; however, predicting its functions is difficult. Methods of analyzing gene expression profiles, for example, microarray, provide functional information of tissues. Liver and peripheral blood leukocytes (PBLs) were collected from Holstein cows subjected to two different physiological conditions (non-pregnant and pregnant), and PBLs were fractionated by gradient cell separation. RNA from PBLs and liver were applied to oligo-DNA microarray and reverse transcription-quantitative polymerase chain reaction (RT-qPCR). It revealed a group of stable bovine liver genes under constant physiological conditions. When they applied to physiological conditions including non-pregnant and pregnant, the profiles of some genes in liver were consistent with those in PBLs. Microarray data subjected to a principal component analysis (PCA) showed that the hepatic gene expression profiles were more consistent with those of granulocytes than mononuclear cells. The relationship of gene profiles in liver with granulocytes was confirmed by RT-qPCR and hierarchical cluster analysis. Gene profiles of granulocytes were more reliable than those of mononuclear cells, which reflected liver functions. These results suggest that the genes expressed in PBLs, particularly granulocytes, may be convenient bioindicators for the diagnosis of clinical disorder and/or detecting aberration of liver functions in cows subjected to different physiological conditions.

    DOI： 10.1111/asj.13324

    PubMed

  • Determination of plasma bone-specific alkaline phosphatase isoenzyme activity in Holstein calves using a commercial agarose gel electrophoresis kit.

    R Onomi, K Hatate, N Yamagishi

    Polish journal of veterinary sciences   22 ( 4 )   789 - 792   2019.12（ ISSN:1505-1773 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：International journal  

    We measured the bone-specific alkaline phosphatase (ALP) isoenzyme activity in 67 plasma samples from 14 newborn Holstein calves using both a conventional method (featuring heat inactivation) and a commercial agarose gel electrophoresis (AGE) kit; the relevant isoenzymes were termed bone-specific ALP (BAP) and ALP isoenzyme 3 (ALP3). We explored whether the AGE kit afforded reliable data when used to analyze samples from Holstein calves. The blood was collected from the jugular vein of each calf immediately prior to the first colostrum feeding (pre-feeding), 20 and 40 h after pre-feeding, and on days 4 and 7; whereas three samples (from three calves) were not obtained. The total plasma ALP activity varied widely, exceeding the ranges of reference values. On electrophoresis, 52 of 67 plasma samples (77.6 %) clearly contained both ALP isoenzyme 2 and ALP3, as did control human serum. The total ALP activity of the 52 samples ranged from 166-1989 U/L (median: 1013 U/L), whereas the values for the other 15 samples (22.4%) exhibiting abnormal isoenzyme fractionation ranged from 1014-5118 U/L (median: 1780 U/L). In the 52 plasma samples exhibiting clearly separated isoenzymes, ALP3 and BAP activities were strongly positively correlated as revealed by Deming regression (y = 0.93x + 22.6, p⟨0.0001) and Bland-Altman analysis (ALP3/BAP activities limit of agreement: -5.1%). Thus, the AGE kit yields useful information on newborn calves, and can replace the conventional method when the total plasma ALP activity is less than approximately 1000 U/L.

    DOI： 10.24425/pjvs.2019.131411

    PubMed

  • Determination of plasma bone-specific alkaline phosphatase isoenzyme activity in Holstein calves using a commercial agarose gel electrophoresis kit Reviewed

    Onomi, R., Hatate, K. and Yamagishi, N.

    Polish Journal of Veterinary Science 雑誌   22 ( 4 )   2019.10

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    Kind of work：Joint Work  

  • Association between Mycoplasma pneumonia outbreaks in calves and Mycoplasma mastitis in milking cows on dairy farms Reviewed

    Itoh, M., Aoki, T., Furuoka, M., Baba, Y., Saitoh, T., Hata, E., Hirano, Y., Senna, K., Yamagishi, N. and Yamada, K

    Japanese Journal of Veterinary Research 雑誌   67 ( 3 )   2019.08

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    Kind of work：Joint Work  

  • Arthrectomy for traumatic proximal interphalangeal arthritis in the lateral digit in a heifer Reviewed

    Goto, A., Tsuzuki, N., Kajihara, A., Moriyama, T., Sasaki, Y., Zushi, N., Hatate, K., Iino, K. and Yamagishi, N.

    Journal of the Hellenic Veterinary Medical Society 雑誌   70 ( 3 )   2019.08

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    Kind of work：Joint Work  

  • Association between Mycoplasma pneumonia outbreaks in calves and Mycoplasma mastitis in milking cows on dairy farms Reviewed

    Megumi Itoh, Takahiro Aoki, Miyuki Furuoka, Yukihiro Baba, Tetsu Saitoh, Eiji Hata, Yuuki Hiranoo, Kazuhiro Sennao, Norio Yamagishi, Kazutaka Yamada

    JAPANESE JOURNAL OF VETERINARY RESEARCH   67 ( 3 )   215 - 220   2019.08（ ISSN:0047-1917 ）

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    Publishing type：Research paper (scientific journal)  

    To clarify the possibility of Mycoplasma mastitis in milking cows from Mycoplasma pneumonia outbreaks in calves, Mycoplasma bovis was isolated over time from nasal swabs of calves and bulk tank milk at two dairy farms where no cases of Mycoplasma mastitis occurred. Isolates were genotypically analyzed using pulsed-field gel electrophoresis. At both farms, Mycoplasma bovis was first detected in bulk tank milk after pneumonia outbreaks in calves, and the genotypes of the isolates from nasal swabs and milk were consistent. These findings indicate that outbreaks of Mycoplasma pneumonia in calves is one of the possible etiologies of Mycoplasma mastitis in dairy herds.

    DOI： 10.14943/jjvr.67.3.215

  • 酪農場における仔牛のマイコプラズマ肺炎流行と乳用牛のマイコプラズマ乳房炎との関連(Association between Mycoplasma pneumonia outbreaks in calves and Mycoplasma mastitis in milking cows on dairy farms)

    Itoh Megumi, Aoki Takahiro, Furuoka Miyuki, Baba Yukihiro, Saitoh Tetsu, Hata Eiji, Hirano Yuuki, Senna Kazuhiro, Yamagishi Norio, Yamada Kazutaka

    Japanese Journal of Veterinary Research   67 ( 3 )   215 - 220   2019.08（ ISSN:0047-1917 ）

  • Influence of transfixation pinning and casting (TPC) configurations on treatment outcomes in bovine tibial fracture. Reviewed

    Kaoru Hatate, Nao Tsuzuki, Ayako Kajihara, Bhuminand Devkota, Kazuya Takehana, Reiichiro Sato, Kimie Iino, Takahiro Aoki, Eiji Takahashi, Norio Yamagishi

    The Journal of veterinary medical science   81 ( 6 )   857 - 862   2019.06（ ISSN:0916-7250 ） （ eISSN:1347-7439 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：Domestic journal  

    The aim of this study was to examine the treatment outcomes of tibial fracture using different configurations of transfixation pinning and casting (TPC) in eight cattle. After pins were inserted to stabilize the fracture site, cast material was placed from the level of the stifle to the hoof (full TPC) in six cases and from the stifle to the proximal metatarsus (partial TPC) in two cases. Five cattle (three full TPC and two partial TPC cases) underwent TPC removal 36-86 days after surgery and resumed productivity. The other three cattle which underwent full TPC suffered from irreversible orthopedic complications within 5 weeks of surgery, while a prolonged healing process was observed in the partial TPC cases. Although TPC is an effective method for treating bovine tibial fracture, full TPC may result in a guarded prognosis in some cattle. However, partial TPC can delay healing. Surgeons should choose the optimal TPC configuration while considering the various factors that affect the healing process.

    DOI： 10.1292/jvms.18-0757

    PubMed

  • Influences of transfixation pinning and casting (TPC) configurations on treatment outcomes in bovine tibial fracture Reviewed

    Hatate, K., Tsuzuki, N., Kajihara, A., Devkota, B., Takehana, K., Sato, R., Iino, K., Aoki, T., Takahashi, E. and Yamagishi, N

    Journal of Veterinary Medical Science 雑誌   81 ( 6 )   2019.06

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  • 牛の脛骨骨折の治療成績に及ぼすピン貫通固定・キャスティング(TPC)配置の影響(Influence of transfixation pinning and casting(TPC) configurations on treatment outcomes in bovine tibial fracture)

    Hatate Kaoru, Tsuzuki Nao, Kajihara Ayako, Devkota Bhuminand, Takehana Kazuya, Sato Reiichiro, Iino Kimie, Aoki Takahiro, Takahashi Eiji, Yamagishi Norio

    The Journal of Veterinary Medical Science   81 ( 6 )   857 - 862   2019.06（ ISSN:0916-7250 ）

  • Determination of serum bone-specific alkaline phosphatase isoenzyme activity in captive Asian elephants (Elephas maximus) using an agarose gel electrophoresis method. Reviewed

    Kazuya Takehana, Rurika Onomi, Kaoru Hatate, Norio Yamagishi

    The Journal of veterinary medical science   81 ( 4 )   551 - 554   2019.04（ ISSN:0916-7250 ） （ eISSN:1347-7439 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：Domestic journal  

    The bone-specific alkaline phosphatase (ALP) isoenzyme activity was measured in 51 serum samples from four captive Asian elephants (Elephas maximus) using a conventional method with wheat germ lectin precipitation and a commercial agarose gel electrophoresis (AGE) kit; the isoenzymes were designated as bone-specific ALP (BAP) and ALP isoenzyme 3 (ALP3), respectively. This study examined the suitability of the AGE kit for analyzing blood biochemistry in Asian elephants. The serum ALP3 and BAP activities were strongly positively correlated and met the evaluation criteria for agreement using Bland-Altman analysis. The results indicate that the AGE kit can be used to examine the blood biochemistry in Asian elephants instead of the conventional method.

    DOI： 10.1292/jvms.18-0688

    PubMed

  • Determination of serum bone-specific alkaline phosphatase isoenzyme activity in captive Asian elephants (Elephas maximus) using an agarose gel electrophoresis method Reviewed

    akehana, K., Onomi, R., Hatate, K. and Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   81 ( 4 )   2019.04

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  • 捕獲アジアゾウ(Elephas maximus)の血清中骨特異的アルカリ性ホスファターゼアイソザイム活性に関するアガロースゲル電気泳動法による測定(Determination of serum bone-specific alkaline phosphatase isoenzyme activity in captive Asian elephants(Elephas maximus) using an agarose gel electrophoresis method)

    Takehana Kazuya, Onomi Rurika, Hatate Kaoru, Yamagishi Norio

    The Journal of Veterinary Medical Science   81 ( 4 )   551 - 554   2019.04（ ISSN:0916-7250 ）

  • The effect of colostrum intake on osteoprotegerin and bone metabolic markers in the blood of newborn calves during the first week of life. Reviewed

    Kaoru Hatate, Mitsunori Kayano, Chiho Kawashima, Masaaki Hanada, Rodrigo C Bicalho, Norio Yamagishi

    The Journal of veterinary medical science   81 ( 1 )   15 - 21   2019.01（ ISSN:0916-7250 ） （ eISSN:1347-7439 ）

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    Publishing type：Research paper (scientific journal)   International / domestic magazine：Domestic journal  

    The aim of this study was to elucidate the bone metabolic status after taking colostrum in newborn calves. Fourteen neonatal calves were randomly allocated to two groups fed either unheated or heated (60°C, 30 min) colostrum three times on the first day (2 l every 10 hr; 6 l in total). Heat treatment on colostrum was to reduce the bone metabolic markers assumed as heat-sensitive. The concentrations of four bone metabolic markers (the enzymes from bone cells or the bone collagen fragments) and a bone protective protein, osteoprotegerin (OPG), were measured in the blood of calves during a week after the birth and in the colostrum. The colostral concentrations of four bone metabolic markers were reduced by heating. Then those circulatory markers peaked after colostrum intake in the calves fed unheated colostrum; whereas those fed heated colostrum did not show such changes. However, the plasma tartrate resistant acid phosphatase 5b (TRAP5b) activity was transiently increased after taking colostrum in both groups. Meanwhile, heating did not decrease colostral OPG and there was no significant rise in the serum OPG concentrations after the first colostrum intake in both groups. The study revealed that the blood concentrations of studied bone metabolic markers depended on those colostral values except for TRAP5b. Based on the plasma TRAP5b changes, accelerated formation of premature osteoclast cells may be induced by colostrum intake. Meanwhile, colostral OPG absorption is less likely to impact on its circulating levels.

    DOI： 10.1292/jvms.18-0453

    PubMed

  • The effect of colostrum intake on osteoprotegerin and bone metabolic markers in the blood of newborn calves during the first week of life. Reviewed

    Hatate、K., Kayano, M., Kawashima, C., Hanada, M., Bicalho, R. C. and Yamagishi, N

    Journal of Veterinary Medical Science 雑誌   81 ( 1 )   2019.01

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  • 生後1週間における新生仔牛の血液中オステオプロテゲリンと骨代謝マーカーに及ぼす初乳摂取の影響(The effect of colostrum intake on osteoprotegerin and bone metabolic markers in the blood of newborn calves during the first week of life)

    Hatate Kaoru, Kayano Mitsunori, Kawashima Chiho, Hanada Masaaki, Bicalho Rodrigo C., Yamagishi Norio

    The Journal of Veterinary Medical Science   81 ( 1 )   15 - 21   2019.01（ ISSN:0916-7250 ）

  • Arthrectomy for traumatic proximal interphalangeal arthritis in the lateral digit in a heifer

    Goto, A., Tsuzuki, N., Kajihara, A., Moriyama, T., Sasaki, Y., Zushi, N., Hatate, K., Iino, K., Yamagishi, N.

    Journal of the Hellenic Veterinary Medical Society   70 ( 4 )   1911 - 1918   2019（ ISSN:1792-2720 ）

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    Publishing type：Research paper (scientific journal)  

    Instructive information on the treatment for chronic deep infections of digital joints in a 9-month-old Holstein heifer is described in this report. Preoperative ultrasonographic and radiographic examinations revealed soft tissue swelling and subchondral bone lysis at the distal part of the proximal phalanx in the lateral digit. Arthrectomy was performed under xylazine sedation to remove infectious articular cartilage tissues. Immature callus formation was observed via radiography at the surgical site by the 28th postoperative day. On the 48th postoperative day, callus fell into disrepair on the radiographs along with aggravation of the locomotion score. After the application of a half-limb cast, the immature callus formed again by the 62nd postoperative day (11 months), and bony callus formation was observed by the 74th postoperative day. Thereafter, the heifer could walk well with marked improvement in the locomotion score. The withers height of the heifer at 13 months (136 cm) was within the range of that in control heifers of the same age on this farm (133 ± 3 cm); however, the body weight (BW) of this heifer (322 kg) was lower than the BW of controls (384 ± 26 kg). The BW gain from 11 to 13 months of age seemed to be higher in the present heifer (+76 kg) than in controls (+55±20 kg), suggesting that BW of the present heifer was returning to the original BW. Based on these observations, we suggested that arthrectomy was an effective treatment option for the present case of digital joint arthritis.

    DOI： 10.12681/jhvms.22244

  • A predictive threshold value for the diagnosis of early pregnancy in cows using interferon-stimulated genes in granulocytes Reviewed

    Yoshino, H., Toji, N., Sasaki, K., Koshi, K., Yamagishi, N., Takahashi, T., Ishiguro-Oonuma, T., Matsuda, H., Yamanouchi, T., Hashiyada, Y., Imai, K., Izaike, Y., Kizaki, K., Hashizume, K

    Theriogenology 雑誌   107   2018.11

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  • Effect of dietary difructose anhydride (DFA) III supplementation on bone mineral density and calcium metabolism in late-lactation dairy cows Reviewed

    96. Maetani, A., Ohtani, M., Hatate, K., Matsumoto, K., Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   80 ( 7 )   2018.07

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  • Short Communication: Serum osteoprotegerin concentrations in periparturient dairy cows Reviewed

    95. Hatate, K., Kawashima, C., Hanada, M., Kayano, M, Yamagishi, N

    Journal of Dairy Science   101   2018.04

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    Kind of work：Joint Work  

  • Effective hands-on treatment of a corneal dermoid in a calf Reviewed

    Hatate, K., Sasaki, J., Katayama, M., Sekiguchi, S., Yamagishi, N

    Journal of the Hellenic Veterinary Medical Society 雑誌   69 ( 1 )   2018.01

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    Kind of work：Joint Work  

  • Serum activities of two bone markers in captive Asian elephants (Elephas maximus) at different ages Reviewed

    Takehana, K., Hatate, K., Yamagishi, N.

    J. Vet. Med. Sci. 雑誌   80 ( 1 )   2018.01

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  • A predictive threshold value for the diagnosis of early pregnancy in cows using interferon-stimulated genes in granulocytes Reviewed

    Yoshino, H., Toji, N., Sasaki, K., Koshi, K., Yamagishi, N., Takahashi, T., Ishiguro-Oonuma, T., Matsuda, H., Yamanouchi, T., Hashiyada, Y., Imai, K., Izaike, Y., Kizaki, K., Hashizume, K

    Theriogenology 雑誌   107   2018.01

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    Kind of work：Joint Work  

  • Serum activities of two bone markers in captive Asian elephants (Elephas maximus) at different ages Reviewed

    Takehana, K., Hatate, K., Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   80 ( 1 )   2018.01

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    Kind of work：Joint Work  

  • Humeral fracture in a Japanese Black calf repaired by closed approach and two methods of external skeletal fixation Reviewed

    Yamagishi, N., Kajiwara, A., Shibano, K. I., Aoki, T., Itoh, M., Hatate, K., Iino K.

    Journal of Veterinary Medical Science 雑誌   79 ( 6 )   2017.06

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  • Evaluation of usefulness of a commercial agarose gel electrophoresis kit (QuickGel SP) for bovine serum protein electrophoresis Reviewed

    Okatsu, Y., Yamagishi, N., Hatate, K., Devkota, B.

    Polish Journal of Veterinary Sciences 雑誌   20 ( 3 )   2017.06

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    Kind of work：Joint Work  

  • Effects of postural change on transesophageal echocardiography views and parameters in healthy dogs Reviewed

    Goya, S., Wada, T., Shimada, K., Hirao, D., Fukushima, R., Yamagishi, N., Shimizu, M., Tanaka, R

    Journal of Veterinary Medical Science 雑誌   79 ( 2 )   2017.02

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  • Polysplenia syndrome with duodenal and pancreatic dysplasia in a Holstein calf: a case report Reviewed

    Kondoh, D., Kawano, T., Kikuchi, T., Hatate, K., Watanabe, K., Sasaki, M., Yamagishi, N., Inokuma, H., Kitamura, N

    BMC Veterinary Research 雑誌   13 ( 1 )   2017.01

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  • Hematological and blood biochemical characteristics of newborn heavy draft foals after dystocia Reviewed

    Chiba, A., Aoki, T., Itoh, M., Yamagishi, N., Shibano, K.

    Journal of Equine Veterinary Science 雑誌   50   2017.01

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  • 過剰排卵処置による採胚性が低い牛における経腟採卵の有効性 Reviewed

    高橋正弘, 平田統一, 山岸則夫

    Journal of Mammalian Ova Research 雑誌   32 ( 4 )   2016.04

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  • Correlation of blood metabolite concentrations and body condition scores with persistent postpartum uterine bacterial infection in dairy cows Reviewed

    Ghanem, M.E., Tezuka, E., Sasaki, K., Takahashi, M., Yamagishi, N., Izaike, Y., Osawa, T.

    J. Reprod. Dev 雑誌   62   2016.04

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    Kind of work：Joint Work  

  • Cytochrome P450 2D14 (CYP2D14) gene deletion variants in the Japanese Black cattle and characterization of their effects on metoclopramide pharmacokinetics Reviewed

    Hamamoto, K., Mizuno, Y., Kijima, M., Abe, T., Kobayashi, E., Kato, M., Yamagishi, N., Furuhama, K

    J. Vet. Sci. Technol 雑誌   7   2016.02

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  • Changes in the plasma levels of several bone markers in newborn calves during the first two days of life Reviewed

    Hatate, K., Shinya, K., Mastsuo-Sato, A., Sasaki, S., Devkota, B., Takahashi, M., Hirata, T., Yamagishi, N

    Journal of Veterinary Medical Science 雑誌   78 ( 2 )   2016.02

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    Kind of work：Joint Work  

  • Plasma fluctuation in estradiol-17β and bone resorption markers around parturition in dairy cows Reviewed

    Devkota, B., Takahashi, M., Sato, S., Sasaki, K., Ueki, A., Osawa, T., Takahashi, M., Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   77 ( 7 )   2015.07

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    Kind of work：Joint Work  

  • Outpatient treatment for humeral fractures in five calves Reviewed

    Yamagishi, N., Devkota, B., Takahashi, M.

    Journal of Veterinary Medical Science 雑誌   76(11)   2014.11

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    Kind of work：Joint Work  

  • Molecular epidemiology and identification of a Staphylococcus aureus clone causing food poisoning outbreaks in Japan Reviewed

    Sato'o, Y., Omoe, K., Naito, I., Ono, H. K., Nakane, A., Sugai, M., Yamagishi, N., Hu, D.-L.

    Journal of Clinical Microbiology 雑誌   52(7)   2014.07

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    Kind of work：Joint Work  

  • Diurnal variation of plasma bone markers in Japanese Black calves Reviewed

    Matsuo, A., Togashi, A., Sasaki, S., Devkota, B., Hirata, T., Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   76(7)   2014.07

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    Kind of work：Joint Work  

  • Microarray-based gene expression profiling of peripheral blood mononuclear cells in dairy cows with experimental hypocalcemia and milk fever Reviewed

    Sasaki, K., Yamagishi, N., Kizaki, K., Sasaki, K., Devkota, B., Hashizume, K.

    Journal of Dairy Science 雑誌   97(1)   2014.01

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    Kind of work：Joint Work  

  • Effects of treatment for anestrus in water buffaloes with PGF and GnRH in comparison with vitamin-mineral supplement, and some factors influencing treatment effects Reviewed

    Devkota, B., Nakao, T., Kobayashi, K., Sato, H., Sah, S. K., Singh, D. K., Dhakal, I. P., Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   75(12)   2013.12

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  • Fluctuation in plasma bone metabolic markers in multiparous and primiparous holstein cows during early to peak lactation Reviewed

    Devkota, B., Takahashi, M., Sasaki, K., Osawa, T., Izaike, Y. and Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   75(9)   2013.09

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    Kind of work：Joint Work  

  • Simple and sensitive method for measurement of metoclopramide in cattle plasma by LC-MS/MS using a multimode chromatography Reviewed

    Simple and sensitive method for measurement of metoclopramide in cattle plasma by LC-MS/MS using a multimode chromatography

    Journal of Veterinary Medical Science 雑誌   75(4)   2013.09

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  • Response of Holstein cows with milk fever to first treatment using two calcium regimens: a retrospective clinical study Reviewed

    Sasaki, K., Sasaki, K., Sato, Y., Devkota, B., Furuhama, K. and Yamagishi, N.

    Journal of Veterinary Medical Science 雑誌   75(3)   2013.03

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    Kind of work：Joint Work  

  • A single-blood-sample method using inulin for estimating feline glomerular filtration rate Reviewed

    Katayama, M., Saito, J., Katayama, R., Yamagishi, N. and Furuhama, K.

    Journal of Veterinary Internal Medicine 雑誌   27(1)   2013.01

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  • 黒毛和種新生子牛における膀胱破裂の1例 Reviewed

    菊地利紀, 懸田和子,菊地 薫, 佐々木恒弥, Danil Kim, Bhuminand Devkota, 宮野安奈, 山岸則夫

    日本獣医師会雑誌 雑誌   65(12)   2012.12

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  • Estimation of glomerular filtration rate in rabbits by a single-sample method using iodixanol Reviewed

    Michigoshi, Y., Katayama, R., Yamagishi, N., Kato, M., Saito, J., Satoh, H. and Furuhama, K.

    Laboratory Animals 雑誌   46(4)   2012.10

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  • Seasonal variation of anestrus conditions in buffaloes (Bubalus bubalis) in Southern Nepal Reviewed

    Devkota, B., Bohora, T. P. and Yamagishi, N.

    Asian Journal of Animal and Veterinary Advances 雑誌   7   2012.09

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  • Simplified procedure for the estimation of feline glomerular filtration rate using iodixanol Reviewed

    Katayama, R., Saito, J., Katayama, M., Yamagishi, N., Yamashita, T. and Furuhama, K.

    American Journal of Veterinary Research 雑誌   73(9)   2012.09

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  • Relationship between pH and temperature in the ruminal fluid of cows, based on a radio-transmission pH-measurement system Reviewed

    Kimura, A., Sato, S., Kato, T., Ikuta, K., Yamagishi, N., Okada, K., Mizuguchi, H. and Ito, K.

    Journal of Veterinary Medical Science 雑誌   74(8)   2012.08

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  • A novel technique of ultrasound-guided brachial plexus block in calves Reviewed

    Iwamoto, J., Yamagishi, N., Sasaki, K., Kim, D., Devkota, B. and Furuhama, K.

    Research in Veterinary Science 雑誌   93(3)   2012.06

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  • Relationship between sex steroid fluctuation and biomarkers of bone resorption in bovine plasma during the estrous cycle Reviewed

    Devkota, B., Itagaki, K., Kim, D., Sasaki, K., Osawa, T., Furuhama, K. and Yamagishi, N.

    The Veterinary Journal 雑誌   194(2)   2012.05

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  • Effects of cortisol secreted via a 12-hour adrenocorticotropic hormone on mineral homeostasis and bone metabolism in ovariectomised cows Reviewed

    Kim, D., Yamagishi, N., Devkota, B. and Furuhama, K.

    Domestic Animal Endocrinology 雑誌   43(3)   2012.05

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  • 外尿道口閉塞と尿膜管遺残構造の高度拡張を呈した尿膜管開存の子牛の1例 Reviewed

    高橋聖大, 石川　弘, Kim, Danil, 佐々木恒弥, Devkota, Bhuminand, 山岸則夫

    産業動物臨床医学雑誌 雑誌   3(1)   2012.04

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  • Dose-response effects of an aqueous formulation of calcitriol and evaluation of renal function in nonpregnant cows Reviewed

    Kim, D., Yamagishi, N., Kawakami, Y., Abe, I., Furuhama, K., Devkota, B., Sasaki, K., Okura, N., Sato, S., and Ohashi, S.

    Journal of Veterinary Medical Science 雑誌   74(4)   2012.04

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  • Simultaneous estimation of the pH of rumen and reticulum fluids of cows using a radio-transmission pH-measurement system Reviewed

    Kimura, A., Sato, S., Goto, H., Yamagishi, N., Okada, K., Mizoguchi, H. and Ito, K.

    Journal of Veterinary Medical Science 雑誌   74(4)   2012.04

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  • A radio transmission pH measurement system for continuous evaluation of fluid pH in the rumen of cows Reviewed

    Sato, S., Kimura, A., Anan, T., Yamagishi, N., Okada, K., Mizuguchi, H. and Ito, K.

    Rveterinary Research Communication 雑誌   36(1)   2012.03

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  • Estimation of glomerular filtration rate in calves using the contrast medium iodixanol Reviewed

    Imai, K., Yamagishi, N., Okura, N., Fukuda, T., Hirata, T., Okada, K., Sato, S. and Furuhama, K.

    The Veterinary Journal 雑誌   193(1)   2012.01

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  • Serum clearance of iodixanol for estimating glomerular filtration rate in calves Reviewed

    Imai, K., Yamagishi, N., Kim, D., Devkota, B., Sato, S., Murayama, I. and Furuhama, K.

    Journal of Veterinary Medical Science 雑誌   73(12)   2011.12

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  • 子牛ならびに育成牛における肢骨折25例の臨床概要：症例報告 Reviewed

    板垣幸樹, 金　檀一, 佐々木恒弥, デブコタ・ブミナンド, 山岸則夫

    産業動物臨床医学雑誌 雑誌   2(4)   2011.11

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  • Colorimetric assay for the quantification of serum iodixanol concentration and its application on estimation of glomerular filtration rate in cattle Reviewed

    Miura, M., Yamagishi, N., Sasaki, K., Kim, D., Devkota, B. and Furuhama, K.

    Research in Veterinary Science 雑誌   93(1)   2011.09

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  • Sequential measurements of glomerular filtration rate in conscious rats by a bolus injection of iodixanol and a single blood sample Reviewed

    Katayama, R., Watanabe, K., Yamagishi, N., Abe, A., Satoh, H., Hazuhisa, K. and Furuhama, K.

    Journal of Applied Toxicology 雑誌   31(4)   2011.05

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  • Using a single blood sample and inulin to estimate glomerular filtration rate in rabbits Reviewed

    Michigoshi, Y., Yamagishi, N., Satoh, H, Kato, M. and Furuhama, K.

    Journal of the American Association for Laboratory Animal Science 雑誌   50(5)   2011.05

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  • Possible role of cysteine-S-conjugate β-lyase in species differences in cisplatin nephrotoxicity Reviewed

    Katayama, R., Nagata, S., Iida, H., Yamagishi, N., Yamashita, T. and Furuhama, K.

    Food and Chemical Toxicology: an International Journal Published for the British Industrial Biological Research Association 雑誌   49(9)   2011.05

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  • Fibrolipoma of a cryptorchid testis in a young bull Reviewed

    Osawa, T., Miura, M., Yamagishi, N., Kim, D., Fukuda, N., Fukuoka, H., Sasaki, J. and Goryo, M.

    Journal of Veterinary Medical Science 雑誌   73(9)   2011.05

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  • Response of plasma bone markers to a single intramuscular administration of calcitriol in dairy cows Reviewed

    Kim, D., Kawakami, Y., Yamagishi, N., Abe, I., Furuhama, K., Devkota, B., Okura, N., Sato, S. and Ohashi, S.

    Research in Veterinary Science 雑誌   90(1)   2011.02

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  • Basal levels and GnRH-induced responses of peripheral testosterone and estrogen in holstein bulls with poor semen quality Reviewed

    Devkota, B., Takahashi, K., Matsuzaki, S., Matsui, M., Miyamoto, A., Yamagishi, N., Osawa, T., Hashizume, T., Izaike, Y. and Miyake, Y.

    Journal of Reproduction and Development 雑誌   57(3)   2011.02

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  • Effects of an oleaginous calcitriol on changes in plasma calcitriol, calcium and bone metabolic markers in dairy cows Reviewed

    Kim, D., Yamagishi, N., Abe, I., Furuhama, K., Devkota, B. and Ohashi, S.

    Journal of Veterinary Medical Science 雑誌   73(2)   2011.02

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  • 臨床症状の回復を示した子牛の不完全重複脊髄症 Reviewed

    關茉莉絵, 佐々木淳, 神志那弘明, 山岸則夫, 岡田啓司, 佐藤　繁, 渡辺　崇, 御領政信

    日本獣医師会雑誌 雑誌   63(9)   2010.09

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  • Changes in plasma bone metabolic markers in periparturient dairy cows Reviewed

    Kim, D., Yamagishi, N., Ueki, A., Miura, M., Saito, F., Sato, S. and Furuhama, K.

    Journal of Veterinary Medical Science 雑誌   72(6)   2010.06

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  • Clinicopathological aspect of dysglycemia in naive and diabetic rats induced by the fluoroquinolone antibacterial gatifloxacin Reviewed

    Nagai, M., Nagata, S., Yamagishi, N., Satoh, H. and Furuhama, K.

    Journal of Veterinary Medical Science 雑誌   72(5)   2010.05

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    Kind of work：Joint Work  

  • Fluorometric method for measuring plasma tartrate-resistant acid phosphatase isoform 5b and its application in cattle Reviewed

    Yamagishi, N., Takehana, K., Kim, D., Miura, M., Hirata, T., Devkota, B., Sato, S. and Furuhama, K.

    Journal of Veterinary Medical Science 雑誌   71(12)   2009.12

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    Kind of work：Joint Work  

  • 黒毛和種子牛における浅趾および深趾屈腱全断裂の1例 Reviewed

    池田亜耶, 大野千明, 池ヶ谷あすか, 三浦 萌, 阿南智顕, 竹鼻一也, 山口英一郎, 金 檀一, 山岸則夫, 佐藤　繁

    日本家畜臨床学会誌 雑誌   32(3)   2009.11

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    Kind of work：Joint Work  

  • Calculation of glomerular filtration rate in conscious rats by the use of a bolus injection of iodixanol and a single blood sample Reviewed

    Katayama, R., Yamaguchi, N., Yamashita, T., Watanabe, S., Satoh, H., Yamagishi, N. and Furuhama, K.

    Journal of pharmacological and toxicological methods 雑誌   61(1)   2009.10

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    Kind of work：Joint Work  

  • Application of a reservoir-type calcitriol transdermal patch in dairy cattle Reviewed

    Yamagishi, N., Namioka, T., Okura, N., Sato, S., Kim, D., Furuhama, K. and Naito, Y.

    Journal of Veterinary Medical Science 雑誌   71(6)   2009.07

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    Kind of work：Joint Work  

  • 11ヵ月齢黒毛和種牛における脛骨骨折の1例 Reviewed

    池ヶ谷あすか, 小笠原裕喜, 池田亜耶, 三浦　萌, 阿南智顕, 竹鼻一也, 山口英一郎, 金　檀一, 佐藤　繁, 山岸則夫

    日本家畜臨床学会誌 雑誌   32(19   2009.05

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    Kind of work：Joint Work  

  • 黒毛和種子牛における痙攣性不全麻痺の１例 Reviewed

    三浦　萌, 福田稔彦, 植木淳史, 池ヶ谷あすか, 池田亜耶, 阿南智顕, 竹鼻一也, 山口英一郎, 金　檀一, 佐藤　繁, 山岸則夫

    日本家畜臨床学会誌 雑誌   32(1)   2009.05

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    Kind of work：Joint Work  

  • 牛における1,25-dihydroxyvitaminD3の経皮吸収 Reviewed

    浪岡　徹, 山岸則夫, 大倉徳太, 赤坂　茂, 阿部　岳, 千田広幸, 佐藤　繁, 内藤善久

    日本家畜臨床学会誌 雑誌   31(1)   2008.04

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    Kind of work：Joint Work  

  • うっ血性心不全の症状を呈した乳牛の2例 Reviewed

    山岸則夫, 大越なつき, 江原和則, 久保田学, 古岡秀文, 古林与志安, 羽田真悟, 宮原和郎, 小岩政照, 大星健治

    日本家畜臨床学会誌 雑誌   31(3)   2008.03

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    Kind of work：Joint Work  

  • Sensitive test for screening Staphylococcus aureus in bovine mastitis by broth cultivation and PCR Reviewed

    Yamagishi, N., Jinkawa, Y., Omoe, K., Makino, S. and Oboshi, K.

    The Veterinary Record 雑誌   161(11)   2007.10

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    Kind of work：Joint Work  

  • 黒毛和種子牛における腸管脱出を伴った臍ヘルニア破裂 Reviewed

    山岸則夫, 大野千明, 浪岡　徹, 入江陽一, 能登はる菜

    日本家畜臨床学会誌 雑誌   30(1)   2007.08

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    Kind of work：Joint Work  

  • Dose response to vaginal administration of 1,25-dihydroxyvitamin D3 to cows Reviewed

    Okura, N., Yamagishi, N., Naito, Y. and Koiwa, M.

    The Veterinary Journal 雑誌   174(1)   2007.08

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    Kind of work：Joint Work  

  • 妊娠末期の乳牛における1,25-dihydroxyvitamin D3の膣粘膜吸収 Reviewed

    大倉徳太, 山岸則夫, 内藤善久, 村中　完, 佐藤　繁, 小岩政照

    日本獣医師会雑誌 雑誌   60(6)   2007.06

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    Kind of work：Joint Work  

  • Calcium metabolism of pregnant rats fed vitamin D-depleted diet Reviewed

    Yamagishi, N., Sassa, H., Sato, R., Taniguchi, K., Okura, N., Sato, S. and Naito, Y.

    Journal of Veterinary Medical Science 雑誌   69(4)   2007.05

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    Kind of work：Joint Work  

  • 乳熱発生率の異なる２牛群における飼料中陽陰イオン差および分娩前後の血中カルシウム濃度 Reviewed

    佐藤　繁, 小門康晃, 佐藤　淳, 佐藤れえ子, 山岸則夫, 大倉徳太, 内藤善久

    日本獣医師会雑誌 雑誌   60(4)   2007.04

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    Kind of work：Joint Work  

  • Tubulointerstitial nephritis causes decreased renal expression and urinary excretion of cauxin, a major urinary protein of the domestic cat Reviewed

    Miyazaki, M., Soeta, S., Yamagishi, N., Taira, T., Suzuki, A. and Yamashita, T

    Research in Veterinary Science 雑誌   82(1)   2007.03

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    Kind of work：Joint Work  

  • Relationship between the first ovulation within three weeks postpartum and subsequent ovarian cycles and fertility in high producing dairy cows. Reviewed

    Kawashima, C., Kaneko, E., Montoya, C. A., Matsui, M., Yamagishi, N., Matsunaga, N., Ishii, M., Kida, K., Miyake, Y. and Miyamoto, A.

    Journal of Reproduction and Development 雑誌   52(4)   2006.09

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    Kind of work：Joint Work  

  • 子牛における腸間膜の長軸捻転の1例 Reviewed

    山岸則夫, 入江陽一, 能登はる菜, 浪岡　徹, 岡田啓司, 大澤健司, 内藤善久

    日本家畜臨床学会誌 雑誌   29(1)   2006.08

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    Kind of work：Joint Work  

  • The expression of genes for transepithelial calcium-transporting proteins in the bovine duodenum Reviewed

    Yamagishi, N., Miyazaki, M. and Naito, Y.

    The Veterinary Journal 雑誌   171(2)   2006.04

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    Kind of work：Joint Work  

  • Practical tips for modified dorsolumbar epidural anesthesia in cattle Reviewed

    Lee, I, Yamagishi, N., Oboshi, K., Sasaki, N. and Yamada, H.

    Journal of Veterinary Science 雑誌   7(1)   2006.04

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    Kind of work：Joint Work  

  • 乳牛の移行期における臨床検査成績とその後の繁殖成績との関係 Reviewed

    江口理香, 山岸則夫, 李仁炯, 大星健治, 高木光博, 中川昭

    日本家畜臨床学会誌 雑誌   28(2)   2005.11

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    Kind of work：Joint Work  

  • Effect of positioning in dorsal recumbency on venous return from the vertebral venous system of a dog Reviewed

    Iseri, T., Yamada, K., Lee, I., Yamagishi, N., Ueno, H. and Wisner, E. R.

    Australian Veterinary Journal 雑誌   83(8)   2005.09

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    Kind of work：Joint Work  

  • Calcium metabolism in cows receiving an intramuscular injection of 1,25-dihydroxyvitamin D3 combined with prostaglandin F2α closely before parturition Reviewed

    Yamagishi, N., Ayukawa, Y., Lee, I., Oboshi, K. and Naito, Y.

    Journal of Veterinary Science 雑誌   6(2)   2005.07

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    Kind of work：Joint Work  

  • Reproductive management with ultrasound scanner-monitoring system for a high-yielding commercial dairy herd reared under stanchion management style Reviewed

    Takagi, M., Yamagishi, N., Lee, I. H., Oboshi, K., Tsuno, M. and Wijayagunawardane, M. P. B.

    Asian Australasian Journal of Animal Sciences 雑誌   18(7)   2005.07

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    Kind of work：Joint Work  

  • Distribution of new methylene blue injected into the caudal epidural space in cattle Reviewed

    Lee, I., Yamagishi, N., Oboshi, K., Ayukawa, Y., Sasaki, N. and Yamada, H.

    The Veterinary Journal 雑誌   169(2)   2005.04

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    Kind of work：Joint Work  

  • A female pseudohermaphrodite Holstein heifer with gonadal mosaicism Reviewed

    Takagi, M., Yamagishi, N., Oboshi, K., Kageyama, S., Hirayama, H., Minamihashi, A., Sasaki, M. and Wijayagunawardane, M. P. B.

    Theriogenology 雑誌   63(1)   2005.02

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    Kind of work：Joint Work  

  • Vaginal absorption of 1,25(OH)2D3 in cattle Reviewed

    Okura, N., Yamagishi, N., Naito, Y., Kanno, K. and Koiwa, M.

    Journal of Dairy Science 雑誌   87(7)   2004.09

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    Kind of work：Joint Work  

  • 乳牛の乾乳後期における第一胃内容および尿性状の簡易臨床検査所見と各種周産期疾病発生との関係 Reviewed

    山岸 則夫, 李 仁炯, 大星 健治, 安藤 道雄, 高木 光博, 中川 昭

    日本家畜臨床学会誌 雑誌   27(1)   2004.08

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    Kind of work：Joint Work  

  • Distribution of new methylene blue injected into the lumbosacral epidural space in cats Reviewed

    Lee, I., Yamagishi, N., Oboshi, K. and Yamada, H.

    Veterinary Anaesthesia and Analgesia 雑誌   31(3)   2004.08

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    Kind of work：Joint Work  

  • Eliminating the effect of epidural fat during dorsolumbar epidural analgesia in cattle Reviewed

    Lee, I., Yamagishi, N., Oboshi, K. and Yamada, H.

    Veterinary Anaesthesia and Analgesia 雑誌   31(2)   2004.05

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    Kind of work：Joint Work  

  • Comparison of xylazine, lidocaine and the two drugs combined for modified dorsolumbar epidural anaesthesia in cattle Reviewed

    Lee, I., Yamagishi, N., Oboshi, K., Ayukawa, Y., Sasaki, N. and Yamada, H.

    The Veterinary Record 雑誌   155(25)   2004.01

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    Kind of work：Joint Work  

  • Antagonistic effects of intravenous or epidural atipamezole on xylazine-induced dorsolumbar epidural analgesia in cattle Reviewed

    Lee, I., Yamagishi, N., Oboshi, K. and Yamada, H.

    The Veterinary Journal 雑誌   166(2)   2003.12

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    Kind of work：Joint Work  

  • Analgesic effect of caudal epidural ketamine in cattle Reviewed

    Lee, I., Yoshiuchi, T., Yamagishi, N., Oboshi, K., Ayukawa, Y., Sasaki, N. and Yamada, H.

    Journal of Veterinary Science 雑誌   4(3)   2003.12

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    Kind of work：Joint Work  

  • Effect of epidural fat on xylazine-induced dorsolumbar epidural analgesia in cattle Reviewed

    Lee, I., Yamagishi, N., Oboshi, K. and Yamada, H.

    The Veterinary Journal 雑誌   165(3)   2003.06

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    Kind of work：Joint Work  

  • Comparative histology of the laminar bone between young calves and foals Reviewed

    Mori, R., Kodaka, T., Sano, T., Yamagishi, N., Asari, M. and Naito, Y.

    Cells Tissues Organs 雑誌   175(1)   2003.02

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    Kind of work：Joint Work  

  • Effect of postural change on lumbar epidural pressure in cattle Reviewed

    Lee, I. H., Yamagishi, N., Oboshi, K. and Yamada, H.

    The Veterinary Journal 雑誌   164(3)   2002.12

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    Kind of work：Joint Work  

  • Expression of calbindin-D9k messenger ribonucleic acid in the gastrointestinal tract of dairy cattle Reviewed

    Yamagishi, N., Yukawa, Y. A., Ishiguro, N., Soeta, S., Lee, I. H., Oboshi, K. and Yamada, H.

    Journal of Veterinary Medicine, Series A 雑誌   49(9)   2002.12

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    Kind of work：Joint Work  

  • Multivariate regression analysis of epidural pressure in cattle Reviewed

    Lee, I., Yamagishi, N., Oboshi, K., Yamada, H. and Ohtani, M.

    American Journal of Veterinary Research 雑誌   63(7)   2002.08

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    Kind of work：Joint Work  

  • Urinary excretion of N-acetyl-β-D-glucosaminidase and its isoenzymes in cats with urinary disease Reviewed

    Sato, R., Soeta, S., Syuto, B., Yamagishi, N., Sato, J. and Naito, Y.

    Journal of Veterinary Medical Science 雑誌   64(4)   2002.04

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    Kind of work：Joint Work  

  • Left paramedian abomasopexy in cattle Reviewed

    Lee, I., Yamagishi, N., Oboshi, K. and Yamada, H.

    Journal of Veterinary Science 雑誌   3(1)   2002.04

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    Kind of work：Joint Work  

  • An immunohistochemical study of endocrine cells in the abomasum of vagotomized calf Reviewed

    Soehartono, R. H., Kitamura, N., Yamagishi, N., Taguchi, K., Yamada, J. and Yamada, H.

    Journal of Veterinary Medical Science 雑誌   64(1)   2002.02

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    Kind of work：Joint Work  

  • Distribution of new methylene blue injected into the dorsolumbar epidural space in cows Reviewed

    Lee, I., Soehartono, R. H., Yamagishi, N., Taguchi, K. and Yamada, H.

    Veterinary Anaesthesia and Analgesia 雑誌   28(3)   2001.12

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    Kind of work：Joint Work  

  • Distribution of new methylene blue injected into the dorsolumbar epidural space in cows Reviewed

    Lee, I. H., Yamagishi, N. and Yamada, H.

    The Veterinary Record 雑誌   149(17)   2001.11

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    Kind of work：Joint Work  

  • The effects of vagotomy on the abomasum in calves: radiography and protein gene product 9.5 immunohistochemistry Reviewed

    Soehartono, R. H., Yamada, H., Yamagishi, N., Kitamura, N. and Taguchi, K.

    Journal of Veterinary Medical Science 雑誌   63(6)   2001.07

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    Kind of work：Joint Work  

  • Plasma atrial natriuretic peptide concentrations in hypocalcaemic cows Reviewed

    Yamagishi, N., Kobayashi, S., Miyamoto, A., Soehartono, R. H., Lee, I. H., Miyahara, K., Naito, Y. and Yamada, H.

    The Veterinary Record 雑誌   148(20)   2001.06

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    Kind of work：Joint Work  

  • Bronchocutaneous fistula in a dog Reviewed

    Yamagishi, N., Yamada, K., Ishikawa, H. and Yamada, H.

    Veterinary Radiology &amp Ultrasound 雑誌   41(5)   2000.09

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    Kind of work：Joint Work  

  • Effects of oral administration of “rumen-bypass” vitamin D3 on vitamin D and calcium metabolism in periparturient cows Reviewed

    Yamagishi, N., Dohmae, H., Shirato, A., Sato, J., Sato, R., and Naito, Y

    Journal of Veterinary Medical Science 雑誌   62(4)   2000.05

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    Kind of work：Joint Work  

  • 子馬の喉嚢鼓張症の1例 Reviewed

    山田明夫, 山岸則夫, 李　仁炯, ラーデン・ハリー・スハルトノ, 田口　清, 大島茂幸

    動物臨床医学 雑誌   9(3)   2000.04

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    Kind of work：Joint Work  

  • Experimental hypocalcemia induced by hemodialysis in goats Reviewed

    Yamagishi, N., Oishi, A., Sato, J., Sato, R., and Naito, Y.

    Journal of Veterinary Medical Science 雑誌   61(12)   1999.12

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    Kind of work：Joint Work  

  • 乳熱の既往歴を持ち心筋壊死性病変を有した分娩後低Ca血症乳牛の1例 Reviewed

    山岸則夫, 佐々木一弥, 佐藤　淳, 佐藤れえ子, 内藤善久

    動物臨床医学 雑誌   8(3)   1999.12

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    Kind of work：Joint Work  

  • フリーストール牛舎飼養乳牛における後肢蹄外旋と蹄底潜在病変との関係 Reviewed

    田口　清, 佐川重信, 山岸則夫, Soehartono, R. H., 山田明夫

    日本獣医師会雑誌 雑誌   52(10)   1999.10

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    Kind of work：Joint Work  

  • 乳牛の心筋壊死病変を伴う低カルシウム血症の臨床所見 Reviewed

    山岸則夫, 佐藤　淳, 佐藤れえ子, 内藤善久

    日本獣医師会雑誌 雑誌   52(8)   1999.08

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    Kind of work：Joint Work  

  • フリーストール牛舎飼養乳牛における削蹄後の後肢蹄形状変化と蹄底潜在病変 Reviewed

    田口　清, 山下真彦, 山岸則夫, 大谷昌之, 池滝　孝, 山田明夫

    日本獣医師会雑誌 雑誌   52(7)   1999.07

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    Kind of work：Joint Work  

  • Pathological changes in the myocardium of hypocalcaemic parturient cows Reviewed

    Yamagishi, N., Ogawa, K., and Naito, Y.

    The Veterinary record 雑誌   144(3)   1999.02

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    Kind of work：Joint Work  

  • 成牛の胸腺型白血病の1例 Reviewed

    山岸則夫, 田口　清, 松下卓見, 古岡秀文, 松井高峰, 山田明夫

    動物臨床医学 雑誌   7(1)   1998.06

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    Kind of work：Joint Work  

  • Calcium metabolism in hypocalcemic cows with myocardial lesion Reviewed

    Yamagishi, N., and Naito, Y.

    Journal of Veterinary Medical Science 雑誌   59(1)   1997.01

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    Kind of work：Joint Work  

  • 乳熱病歴を有する乳牛の分娩前後における血漿中上皮小体ホルモンおよび1,25-dihydroxyvitamin D濃度の変動 Reviewed

    山岸則夫, 大泉俊昭, 佐藤れえ子, 内藤善久

    日本獣医師会雑誌 雑誌   49(10)   1996.10

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    Kind of work：Joint Work  

  • Peripartum heart disease in cows Reviewed

    Yamagishi, N., Okada, H., Koiwa, M., Kudo, K., Matsuo, N., and Naito, Y.

    Journal of Comparative Pathology 雑誌   113(4)   1995.11

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    Kind of work：Joint Work  

▼display all

Books and Other Publications

  • 周産期疾から牛を守る

    山岸則夫（ Role： Contributor ,  低カルシウム血症）

    デーリィマン社  2022.10  （ ISBN:9784864530873 ）

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    Total pages：6   Responsible for pages：17-21  

  • 周産期疾から牛を守る

    山岸則夫（ Role： Contributor ,  低カルシウム血症）

    デーリィマン社  2022.10  （ ISBN:9784864530873 ）

    　More details

    Total pages：6   Responsible for pages：17-21  

  • 獣医内科学　第3版　産業動物編

    山岸則夫（ Role： Edit）

    文永堂  2022.03  （ ISBN:978-4-8300-3283-7 ）

  • 獣医内科学 第3版 産業動物編

    山岸則夫（ Role： Edit）

    文永堂  2022.03  （ ISBN:9784830032837 ）

  • 主要症状を基礎にした牛の臨床３

    山岸則夫（分担）

    デーリィマン社  2020.05 

  • 主要症状を基礎にした牛の臨床３

    山岸則夫

    デーリィマン社  2020.05 

  • 獣医学教育モデル・コア・カリキュラム準拠・獣医臨床薬理学

    山岸則夫（分担）

    近代出版  2017.12 

  • テレビ・ドクター 4 よく分かる乳牛の病気100選（DAIRYMAN臨時増刊号

    山岸則夫（分担）

    デーリィマン社  2017.10 

  • コアカリ産業動物臨床学［コアカリ獣医内科学（産業動物臨床学）編集委員会編集］

    山岸則夫（分担）

    文永堂出版  2016.12 

  • 獣医内科学・大動物編・第2版

    山岸則夫（分担）

    文永堂出版  2014.05 

  • 子牛の医学

    山岸則夫（分担）

    緑書房  2014.03 

  • ６． テレビ・ドクター３：乳牛の病気と対処100選

    山岸則夫（分担）

    デーリィマン社  2007.10 

  • 獣医内科学・大動物編（日本獣医内科学アカデミー編）

    山岸則夫（分担）

    文永堂出版  2005.05 

  • 新版主要症状を基礎にした牛の臨床

    山岸則夫（分担）

    デーリィマン社  2002.08 

  • 犬の尿路結石症（獣医臨床シリーズ2001年版, C. A. Osborneら著, 宇塚雄次監訳）

    山岸則夫（分担）

    学窓社  2001.01 

▼display all

MISC

  • 子牛の下肢骨折における診断と治療の原則

    山岸 則夫

    家畜診療   68 ( 8 )   411 - 418   2021.08（ ISSN:0287-0754 ）

  • 貫通固定ピンキャスト(TPC)で治療したホルスタイン育成牛の橈尺骨骨折の1例

    森山 友恵, 後藤 聡, 都築 直, 川島 秀平, 近藤 拓, 山岸 則夫

    産業動物臨床医学雑誌   12 ( 2 )   78 - 84   2021.08（ ISSN:1884-684X ） （ eISSN:2187-2805 ）

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    ホルスタイン種の雌育成牛(238日齢、体重247kg)における左橈尺骨骨幹の非開放性斜骨折と診断した症例について、貫通固定ピンとフルリムキャストを用いた貫通固定ピンキャスト(TPC)法による治療を行った。術中は塩酸キシラジンの静脈内投与(0.2mg/kg)で仰臥位保定後、塩酸メデトミジンの定量持続点滴(20μg/kg/hr)にて鎮静を維持し、2%リドカイン10mlによる腕神経叢ブロックで疼痛管理した。患肢の牽引と骨把持鉗子により骨折端を合わせて固定し、整形外科用パワードリルを用いて直径4.0mmの貫通固定ピンを、骨折端を挟む遠位および近位側橈骨骨幹にピンを各2本、近位および遠位骨の骨折端および骨折面を貫通するようにピン3本をそれぞれ貫通させた。さらにその上からフルリムキャストを巻き、キャスティングテープ表面から露出したピンは約4cmで切断し、即時重合レジンで各ピンの切断部を被覆・結合した。手術時間は80分であった。症例は覚醒後すぐに起立歩行可能であり同日中に退院、単房で個別飼育とし、術後1週間の抗生物質製剤投与を行った。術後48日目にX線所見にて明瞭な仮骨形成を認めたため、手根関節以下の遠位側のキャスティングテープ部分を切断・除去した。術後81日目にキシラジン鎮静下でTPC全てを除去し治癒とした。治療期間中および治療後の起立歩行は問題なく、その後の発育も順調であった。牛の橈骨骨折では内固定で高い治癒率が報告されているが治療にかかるコスト、手術時間および難易度、術後合併症のリスクにおいてTPCは内固定よりも生産動物である本症例にメリットを与えた。牛の骨折治療では体重が予後に影響を与え、さらにTPCでは使用する貫通固定ピンの太さ・本数・配置ならびにフレームであるキャストの長さが、骨折端の安定性や固定の強度に影響を与える。体重が重い個体の橈骨骨折をTPCにて治療した報告は限られており、本症例は今後の治療の際の良いモデルとなった。(著者抄録)

  • 子牛の下肢骨折における診断と治療の原則

    山岸 則夫

    家畜診療   68 ( 8 )   411 - 418   2021.08（ ISSN:0287-0754 ）

  • 子牛の下肢骨折における診断と治療の原則

    山岸則夫

    家畜診療   68 ( 8 )   2021.07

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  • 牛の臨床外科学：術前準備（手術者・術野の準備）−後編−

    山岸則夫

    臨床獣医   39 ( 6 )   2021.06

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  • 牛の臨床外科学(第11回) 術前準備(手術者・術野の準備)(後編)

    山岸 則夫

    臨床獣医   39 ( 6 )   43 - 47   2021.06（ ISSN:0912-1501 ）

  • 牛の臨床外科学(第11回)　術前準備(手術者・術野の準備)(後編)

    山岸 則夫

    臨床獣医   39 ( 6 )   43 - 47   2021.06（ ISSN:0912-1501 ）

  • 牛の臨床外科学：術前準備（手術者・術野の準備）−前編−

    山岸則夫

    臨床医学   39 ( 5 )   2021.05

  • 乾乳牛へのペレット状グリセリン給与が分娩前後の栄養代謝状態および分娩後の疾病発生や乳量、繁殖機能回復へ及ぼす影響

    川島 千帆, 近藤 萌里, 長谷川 類, 畔上 正晴, 大井 樹里, 澁谷 俊樹, 杉本 優香, 山岸 則夫

    日本畜産学会報   92 ( 2 )   159 - 168   2021.05（ ISSN:1346-907X ） （ eISSN:1880-8255 ）

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    乾乳牛へのペレット状グリセリン給与が分娩前後の栄養代謝状態と分娩後の疾病発生や生産性へ及ぼす影響を調査した。分娩予定3週前から分娩までグリセリン80g含有ペレット(Gly、20頭)またはプラセボペレット(Cnt、21頭)を毎日給与した。Cntのルーメンフィルスコアは分娩前に低下したが(P<0.05)、Glyで変化せず、分娩前の血中β-ヒドロキシ酪酸(BHBA)濃度はGlyで低かった(P<0.05)。分娩前後のボディコンディションスコア(BCS)はGlyで高かった(前;P<0.05、後;P=0.06)。ケトーシス発症頭数に差はないが治療牛の血中BHBA濃度はGlyで低い傾向にあった(P=0.07)。以上より、分娩予定3週前からのグリセリンペレット給与は給与中の採食量を一定に保ち脂質代謝を改善させ、分娩前後のBCSの適切な維持やケトーシスの症状を緩和させる可能性が示された。(著者抄録)

    Other URL： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2021&ichushi_jid=J01149&link_issn=&doc_id=20210531220004&doc_link_id=10.2508%2Fchikusan.92.159&url=https%3A%2F%2Fdoi.org%2F10.2508%2Fchikusan.92.159&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  • 牛の臨床外科学(第10回)　術前準備(手術者・術野の準備)(前編)

    山岸 則夫

    臨床獣医   39 ( 5 )   35 - 39   2021.05（ ISSN:0912-1501 ）

  • 牛の臨床外科学(第10回) 術前準備(手術者・術野の準備)(前編)

    山岸 則夫

    臨床獣医   39 ( 5 )   35 - 39   2021.05（ ISSN:0912-1501 ）

  • 観血去勢後の手術部位感染により陰嚢膿瘍を形成した黒毛和種去勢牛の3例

    後藤 聡, 千葉 暁子, 森山 友恵, 飯野 君枝, 山岸 則夫

    産業動物臨床医学雑誌   11 ( 2 )   82 - 86   2020.08（ ISSN:1884-684X ） （ eISSN:2187-2805 ）

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    国内の肉牛生産現場において、去勢は最も頻繁に行われる外科処置の1つである。去勢は生産性向上の観点から畜産現場で広く実施され、なかでも観血法による精巣摘出が主流とされている。今回、観血去勢後の手術部位感染(surgical site infection:SSI)により陰嚢膿瘍を形成した黒毛和種去勢牛3頭に対して、一般身体検査および超音波診断装置を用いて陰嚢や精索の形状、膿様物の有無を精査した後、外科的治療を行った。局所的な陰嚢膿瘍と診断した2例において、膿瘍は非感染部との境界が明瞭であったことから陰嚢の全切除を行った。1例において精索は膿瘍として大きく腫大したまま腹腔内深部へと連絡していたことから、陰嚢切除ならびに精索瘻による腹腔内膿瘍の排膿処置を行った。術後には継続的な精索瘻の内腔の洗浄を行い、精索の大きさは退縮、排膿の量も減少、手術後42日目には精索瘻の炎症消退と創傷収縮を認めた。いずれの症例も治癒転帰となったことから、陰嚢切除ならびに精索瘻による腹腔内膿瘍の排膿は有効な治療法であったと考えられた。今回の3例は、獣医師ならびに畜産関係者に対して、簡易外科手技である去勢術の衛生的な手技実施ならびにSSI予防対策に努めることの必要を再認識させる重要な症例であった。(著者抄録)

  • 観血去勢後の手術部位感染により陰嚢膿瘍を形成した黒毛和種去勢牛の3例

    後藤 聡, 千葉 暁子, 森山 友恵, 飯野 君枝, 山岸 則夫

    産業動物臨床医学雑誌   11 ( 2 )   82 - 86   2020.08（ ISSN:1884-684X ） （ eISSN:2187-2805 ）

    　More details

    国内の肉牛生産現場において、去勢は最も頻繁に行われる外科処置の1つである。去勢は生産性向上の観点から畜産現場で広く実施され、なかでも観血法による精巣摘出が主流とされている。今回、観血去勢後の手術部位感染(surgical site infection:SSI)により陰嚢膿瘍を形成した黒毛和種去勢牛3頭に対して、一般身体検査および超音波診断装置を用いて陰嚢や精索の形状、膿様物の有無を精査した後、外科的治療を行った。局所的な陰嚢膿瘍と診断した2例において、膿瘍は非感染部との境界が明瞭であったことから陰嚢の全切除を行った。1例において精索は膿瘍として大きく腫大したまま腹腔内深部へと連絡していたことから、陰嚢切除ならびに精索瘻による腹腔内膿瘍の排膿処置を行った。術後には継続的な精索瘻の内腔の洗浄を行い、精索の大きさは退縮、排膿の量も減少、手術後42日目には精索瘻の炎症消退と創傷収縮を認めた。いずれの症例も治癒転帰となったことから、陰嚢切除ならびに精索瘻による腹腔内膿瘍の排膿は有効な治療法であったと考えられた。今回の3例は、獣医師ならびに畜産関係者に対して、簡易外科手技である去勢術の衛生的な手技実施ならびにSSI予防対策に努めることの必要を再認識させる重要な症例であった。(著者抄録)

    Other URL： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2020&ichushi_jid=J05640&link_issn=&doc_id=20200911450004&doc_link_id=%2Fdd7sador%2F2020%2F001102%2F004%2F0082-0086%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fdd7sador%2F2020%2F001102%2F004%2F0082-0086%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

  • ウシの脛骨骨折における貫通ピンキャスト(TPC)のフレーム形状と治療結果

    羽立薫, 羽立薫, 羽立薫, 都築直, 加治原彩子, 竹鼻一也, 竹鼻一也, 佐藤礼一郎, 飯野君枝, 山岸則夫, 山岸則夫, 山岸則夫

    日本獣医学会学術集会講演要旨集   162回   448 - 448   2019.08（ ISSN:1347-8621 ）

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  • 研修 参加型臨床実習〜臨床実習は参加型になってどう変わったのか〜 北海道大学-帯広畜産大学共同獣医学課程における産業動物臨床実習の取組み

    山岸 則夫

    日本獣医学会学術集会講演要旨集   162回   273 - 273   2019.08（ ISSN:1347-8621 ）

  • 泌乳後期の乳牛へのDifructose anhydride(DFA)III給与が骨密度に与える影響

    前谷 文美, 大谷 昌之, 羽立 薫, 松本 高太郎, 山岸 則夫

    日本獣医学会学術集会講演要旨集   162回   448 - 448   2019.08（ ISSN:1347-8621 ）

  • 乳牛の分娩前後における血清アルカリフォスファターゼ分画活性値の推移

    大呑 瑠莉花, 羽立 薫, 川島 千帆, 花田 正明, 山岸 則夫

    日本獣医学会学術集会講演要旨集   162回   454 - 454   2019.08（ ISSN:1347-8621 ）

  • 胎子品種が異なる乳用未経産牛の妊娠末期や分娩直後,臍帯および産子の血液性状の差異

    川島千帆, 粂咲良, 山岸則夫

    日本畜産学会大会講演要旨   125回   215 - 215   2019.03（ ISSN:1342-4688 ）

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  • 乳牛の分娩後低カルシウム血症の病因と病態

    山岸則夫

    産業動物臨床医学雑誌   5 ( 3 )   2014.03

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  • 乳熱の病態

    山岸則夫

    日本獣医師会雑誌   68   2012.04

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Presentations

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Works

  • 乳牛の消化管におけるECaC遺伝子の発現解析

    2006

Industrial Property Rights

  • METHOD OF PREVENTING, MEDICATING AND/OR TREATING HYPOCALCAEMIA OF DOMESTIC MAMMAL

    Yoshihisa Naito, Norio Yamagishi, Norimoto Okura

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    property_type：Patent 

    Application no：EP1719513A1 

Collaborative research (seeds) keywords

  • 動物の臨床血液生化学、とくにアガロース電気泳動装置を用いた解析

  • Stress and welfare assessment of rare captive small ruminants in Japan

Grant-in-Aid for Scientific Research

  • Establishment of a clinical chemistry test method using a medical agarose electrophoresis kit for captive Asian elephants.

    Grant-in-Aid for Scientific Research(C)  2024

  • 乳牛の消化管におけるvitamin D receptor遺伝子の解析

    2007

Acceptance of Researcher

  • 2023  Number of researchers：1

Outline of education staff

  • Lectures and practical training on veterinary education, especially large animal clinical medicine (internal medicine and surgery)

Charge of on-campus class subject

  • 小動物基礎臨床実習

    2024   Intensive lecture   Undergraduate

  • 獣医学概論

    2024   Weekly class   Undergraduate

  • 初年次ゼミナール

    2024   Weekly class   Graduate school

  • 産業動物生産獣医療

    2024   Weekly class   Undergraduate

  • 獣医科学英語演習

    2024   Intensive lecture   Undergraduate

  • 獣医学関連法規

    2024   Weekly class   Undergraduate

  • 獣医学概論

    2024   Intensive lecture   Undergraduate

  • 獣医臨床栄養学

    2024   Weekly class   Undergraduate

  • 獣医科学特別演習1

    2022   Intensive lecture   Graduate school

  • 産業動物生産獣医療

    2022   Weekly class   Undergraduate

  • 獣医臨床栄養学

    2022   Weekly class   Undergraduate

  • 獣医科学特別演習1

    2022   Intensive lecture   Graduate school

  • 国際・国内インターンシップ

    2022   Intensive lecture   Graduate school

  • 獣医科学特別研究1

    2022   Intensive lecture   Graduate school

  • 獣医科学特別研究1

    2022   Intensive lecture   Graduate school

  • 大動物診断治療学A

    2022   Intensive lecture   Undergraduate

  • 大動物臨床A

    2022   Intensive lecture   Undergraduate

  • 大動物臨床B

    2022   Intensive lecture   Undergraduate

  • 牧場実習

    2022   Intensive lecture   Undergraduate

  • 大動物野外診療実習

    2022   Intensive lecture   Undergraduate

  • 大動物診療実習

    2022   Intensive lecture   Undergraduate

  • 臨床基礎実習

    2022   Weekly class   Undergraduate

  • 畜産学実習

    2022   Intensive lecture   Undergraduate

  • 獣医体験演習

    2022   Weekly class   Undergraduate

  • 食料生産実習

    2022   Intensive lecture   Undergraduate

  • 食料生産実習

    2022   Intensive lecture   Undergraduate

  • Practical Training for Food  production

    2021   Practical Training  

  • Practice for Large Animal Clinics

    2021   Practical Training  

  • Field Practice for Large Animal Clinics

    2021   Practical Training  

  • Stock Farm Practice

    2021   Practical Training  

  • Large Animal Practice B

    2021    

  • Large Animal Practice A

    2021   Practical Training  

  • Diagnosis and Treatment in Large Animals A

    2021    

  • Veterinary Clinical Nutrition

    2021    

  • Introduction to Life, Environment, and Advanced Sciences

    2021    

  • Farm Animal Production Medicine

    2021    

  • Basic clinical practices

    2021   Practical Training  

▼display all

Charge of off-campus class subject

  • 臨床基礎実習

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

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    Country：Japan

  • 畜産学実習

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 産業動物生産獣医療

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 獣医臨床栄養学

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 獣医科学特別研究1

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 獣医科学特別演習1

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 獣医体験演習

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 牧場実習

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 大動物野外診療実習

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 大動物診療実習

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 大動物診断治療学A

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 大動物臨床B

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

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    Country：Japan

  • 大動物臨床A

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 国際・国内インターンシップ

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • 食料生産実習

    2022.04
    -
    2023.03
    Institution：Osaka Metropolitan University

    　More details

    Country：Japan

  • Large Animal Practice A

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Farm Animal Production Medicine

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Introduction to Life, Environment, and Advanced Sciences

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Veterinary Clinical Nutrition

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Stock Farm Practice

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Field Practice for Large Animal Clinics

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Practice for Large Animal Clinics

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Diagnosis and Treatment in Large Animals A

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Large Animal Practice B

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Basic clinical practices

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

    　More details

    Country：Japan

  • Practical Training for Food  production

    2021.04
    -
    2022.03
    Institution：Osaka Prefecture University

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    Country：Japan

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Number of instructed thesis, researches

  • 2023

    Number of instructed the graduation thesis：1  Number of graduation thesis reviews：3

    [Number of instructed the Master's Program] (previous term)：0 

    [Number of master's thesis reviews] (chief)：0  [Number of master's thesis reviews] (vice-chief)：0

    [Number of doctoral thesis reviews] (chief)：0  [Number of doctoral thesis reviews] (vice-chief)：1

  • 2022

    Number of instructed the graduation thesis：0  Number of graduation thesis reviews：0

    [Number of instructed the Master's Program] (previous term)：0  [Number of instructed the Master's Program] (letter term)：0

    [Number of master's thesis reviews] (chief)：0  [Number of master's thesis reviews] (vice-chief)：0

    [Number of doctoral thesis reviews] (chief)：0  [Number of doctoral thesis reviews] (vice-chief)：1

Social Activities　⇒ Link to the list of Social Activities

  • 獣医学教育支援機構　幹事 共用試験センター統括委員会　委員

    2018.10 - Now

  • 獣医学教育支援機構　獣医学共用試験センター長

    2018.10 - Now

  • 獣医学教育支援機構 幹事 共用試験センター統括委員会 委員

    2018.10 - Now

  • 獣医学教育支援機構 獣医学共用試験センター長

    2018.10 - Now

Academic Activities

  • Journal of Veteriary Medical Science, Section Editor

    2021.01 - Now

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    Type：Peer review 

  • Journal of Veteriary Medical Science, Section Editor

    2021.01 - Now

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    Type：Peer review 

Job title

  • Job title within the department

    Graduate School of Veterinary Science 

    研究科長  2024.04

  • Job title within the department

    Graduate School of Veterinary Science 

    研究院長  2024.04

  • Job title within the department

    School of Veterinary Science 

    学部長  2024.04

Original item / Special report (Management administration)

  • 2023

    　 More details

    Original item：教育研究審議会委員（獣医学研究科）

  • 2022

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    Original item：教育研究審議会委員（獣医学研究科）